首页 > 最新文献

Journal of Cancer and Tumor International最新文献

英文 中文
Persistent Postmastectomy Pain in Breast Cancer Patients: Incidence, Pain Characteristics and Effects on Quality of Life 乳腺癌术后持续性疼痛的发生率、疼痛特征及对生活质量的影响
Pub Date : 2018-12-08 DOI: 10.9734/JCTI/2018/44781
R. Arslan, E. Obuz, Y. Erhan, E. Erhan, H. Aydede, E. Kara
{"title":"Persistent Postmastectomy Pain in Breast Cancer Patients: Incidence, Pain Characteristics and Effects on Quality of Life","authors":"R. Arslan, E. Obuz, Y. Erhan, E. Erhan, H. Aydede, E. Kara","doi":"10.9734/JCTI/2018/44781","DOIUrl":"https://doi.org/10.9734/JCTI/2018/44781","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126750372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Histopathologic Patterns of Urological Malignancies in Calabar, South-Southern Nigeria: A Ten-Year Review 尼日利亚南部卡拉巴市泌尿系统恶性肿瘤的组织病理学模式:十年回顾
Pub Date : 2018-11-17 DOI: 10.9734/JCTI/2018/43949
E. Isiwele, I. Bassey, E. Ikpi, G. Enakirerhi, F. Otobo, A. Essiet, P. D. Ekwere
Background: Malignant diseases have become more prominent in Nigeria over the past years with urological malignancies contributing significantly to cancer related morbidity and mortality. Cancers of the prostate, bladder, kidney, testis and penis are documented as the most common group of non-cutaneous cancers. This study was carried out to document the pattern and distribution of urological malignancies seen in a tertiary hospital in Calabar, South-southern Nigeria over a 10-year period. Materials and Methods: This was a retrospective study carried out in the Department of Urology, University of Calabar Teaching Hospital, Nigeria. Cases of all pathologically proven urological malignancies managed between January 2006 and December 2015 were included. Data were retrieved from patients' case notes, operation registers and histopathology records. The histological slides of all cases were retrieved and reviewed. Patients' demographic data, tumour Original Research Article Isiwele et al.; JCTI, 8(1): 1-10, 2018; Article no.JCTI.43949 2 site, histologic diagnoses as well as pathologic grades of malignancies were extracted and analysed. Results: A total of 617 cases of urological malignancies were included in the study over the 10 years under review, comprising of 598 (96.9%) males and 19 (3.1%) females giving a male: female ratio of 31.5:1. There were 600 adults (97.2%) and 17 children (2.8%). The median age was 43 years with range of 1-100 years. The frequency of urological cancers showed prostate cancer to be the most common urologic cancer as follows: Prostate cancer constituted 564 (91.4%), Kidneys 27 (4.4%), Urinary bladder 9 (1.5%), Testis 8 (1.3%), Scrotum 5 (0.8%), Penis 2 (0.3%) and Urethra 2 (0.3%). The most common histologic type of prostate cancer was adenocarcinoma with Gleason Grade III being the commonest grade. Out of the 17 childhood urological malignancies recorded, 13(76.47%) were kidney malignancies, 3 (17.65%) were testicular malignancies and 1 (5.88%) was bladder malignancy. Conclusion: Prostate cancer is by far the commonest urological malignancy, with renal cancer being a distant second in Calabar, ahead of bladder cancers. Childhood urological malignancies in Calabar are predominantly nephroblastomas. The need for increased effort in creating awareness about prostate cancer and for routine screening is reiterated.
背景:在过去几年中,恶性疾病在尼日利亚变得更加突出,泌尿系统恶性肿瘤对癌症相关的发病率和死亡率起着重要作用。前列腺癌、膀胱癌、肾癌、睾丸癌和阴茎癌是最常见的非皮肤癌症。本研究旨在记录尼日利亚南部卡拉巴尔一家三级医院10年来泌尿系统恶性肿瘤的模式和分布。材料与方法:本研究是在尼日利亚卡拉巴尔大学教学医院泌尿外科进行的回顾性研究。纳入2006年1月至2015年12月期间病理证实的所有泌尿系统恶性肿瘤病例。数据来源于患者的病例记录、手术记录和组织病理学记录。对所有病例的组织学切片进行检索和复习。患者人口统计资料,肿瘤;生物工程学报,8(1):1-10,2018;文章no.JCTI。提取并分析肿瘤的部位、组织学诊断及病理分级。结果:10年间共纳入617例泌尿系统恶性肿瘤,其中男性598例(96.9%),女性19例(3.1%),男女比例为31.5:1。成人600人(97.2%),儿童17人(2.8%)。中位年龄43岁,范围1 ~ 100岁。泌尿系统肿瘤的发生频率显示,前列腺癌是最常见的泌尿系统肿瘤:前列腺癌564例(91.4%),其次是肾脏27例(4.4%),膀胱9例(1.5%),睾丸8例(1.3%),阴囊5例(0.8%),阴茎2例(0.3%),尿道2例(0.3%)。前列腺癌最常见的组织学类型是腺癌,Gleason III级是最常见的级别。17例小儿泌尿系统恶性肿瘤中,肾恶性肿瘤13例(76.47%),睾丸恶性肿瘤3例(17.65%),膀胱恶性肿瘤1例(5.88%)。结论:前列腺癌是迄今为止最常见的泌尿系统恶性肿瘤,其次是肾癌,排在膀胱癌之前。儿童泌尿系统恶性肿瘤主要是肾母细胞瘤。重申需要加大努力,提高人们对前列腺癌的认识,并进行常规筛查。
{"title":"Histopathologic Patterns of Urological Malignancies in Calabar, South-Southern Nigeria: A Ten-Year Review","authors":"E. Isiwele, I. Bassey, E. Ikpi, G. Enakirerhi, F. Otobo, A. Essiet, P. D. Ekwere","doi":"10.9734/JCTI/2018/43949","DOIUrl":"https://doi.org/10.9734/JCTI/2018/43949","url":null,"abstract":"Background: Malignant diseases have become more prominent in Nigeria over the past years with urological malignancies contributing significantly to cancer related morbidity and mortality. Cancers of the prostate, bladder, kidney, testis and penis are documented as the most common group of non-cutaneous cancers. This study was carried out to document the pattern and distribution of urological malignancies seen in a tertiary hospital in Calabar, South-southern Nigeria over a 10-year period. Materials and Methods: This was a retrospective study carried out in the Department of Urology, University of Calabar Teaching Hospital, Nigeria. Cases of all pathologically proven urological malignancies managed between January 2006 and December 2015 were included. Data were retrieved from patients' case notes, operation registers and histopathology records. The histological slides of all cases were retrieved and reviewed. Patients' demographic data, tumour Original Research Article Isiwele et al.; JCTI, 8(1): 1-10, 2018; Article no.JCTI.43949 2 site, histologic diagnoses as well as pathologic grades of malignancies were extracted and analysed. Results: A total of 617 cases of urological malignancies were included in the study over the 10 years under review, comprising of 598 (96.9%) males and 19 (3.1%) females giving a male: female ratio of 31.5:1. There were 600 adults (97.2%) and 17 children (2.8%). The median age was 43 years with range of 1-100 years. The frequency of urological cancers showed prostate cancer to be the most common urologic cancer as follows: Prostate cancer constituted 564 (91.4%), Kidneys 27 (4.4%), Urinary bladder 9 (1.5%), Testis 8 (1.3%), Scrotum 5 (0.8%), Penis 2 (0.3%) and Urethra 2 (0.3%). The most common histologic type of prostate cancer was adenocarcinoma with Gleason Grade III being the commonest grade. Out of the 17 childhood urological malignancies recorded, 13(76.47%) were kidney malignancies, 3 (17.65%) were testicular malignancies and 1 (5.88%) was bladder malignancy. Conclusion: Prostate cancer is by far the commonest urological malignancy, with renal cancer being a distant second in Calabar, ahead of bladder cancers. Childhood urological malignancies in Calabar are predominantly nephroblastomas. The need for increased effort in creating awareness about prostate cancer and for routine screening is reiterated.","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128482678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
The Therapeutic Impact of Lymphadenectomy in the Management of Epithelial Ovarian Cancer: A Single Institution Experience 淋巴切除术对上皮性卵巢癌治疗的影响:单一机构的经验
Pub Date : 2018-11-08 DOI: 10.9734/jcti/2018/44996
K. A. Kulkarni, T. Premalatha, G. Sumangala, Geeta Acharya, S. Selvam, Vishakha C. Bidkar, J. Crasta, E. Vallikad
{"title":"The Therapeutic Impact of Lymphadenectomy in the Management of Epithelial Ovarian Cancer: A Single Institution Experience","authors":"K. A. Kulkarni, T. Premalatha, G. Sumangala, Geeta Acharya, S. Selvam, Vishakha C. Bidkar, J. Crasta, E. Vallikad","doi":"10.9734/jcti/2018/44996","DOIUrl":"https://doi.org/10.9734/jcti/2018/44996","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132029419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Women’s Awareness and Factors Affecting Utilization of Cervical Cancer Screening Services in the Ejisu-Juaben Municipality of Ghana 加纳Ejisu-Juaben市妇女对宫颈癌筛查服务利用的认识和影响因素
Pub Date : 2018-10-05 DOI: 10.9734/jcti/2018/43971
Esther Akua Konadu Prempeh
{"title":"Women’s Awareness and Factors Affecting Utilization of Cervical Cancer Screening Services in the Ejisu-Juaben Municipality of Ghana","authors":"Esther Akua Konadu Prempeh","doi":"10.9734/jcti/2018/43971","DOIUrl":"https://doi.org/10.9734/jcti/2018/43971","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129058430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Knowledge of Cervical Cancer and Its Risk Factors, Attitudes and Practices towards Pap Smear Screening among Students in the University of Buea, Cameroon 喀麦隆布埃亚大学学生对宫颈癌及其危险因素的认识、对子宫颈抹片检查的态度和做法
Pub Date : 2018-09-27 DOI: 10.9734/JCTI/2018/43965
G. Halle-Ekane, Derick Nembulefack, G. E. Orock, P. N. Fon, A. Tazinya, P. Tebeu
Introduction: Cancer of the cervix is the second most common gynaecological malignancy and the leading cause of cancer mortality among women in Cameroon. Knowledge and attitudes toward cervical cancer screening depend largely on gender and educational level. The objective of Original Research Article Halle-Ekane et al.; JCTI, 7(4): 1-11, 2018; Article no.JCTI.43965 2 this study was to determine the knowledge of cervical cancer and the attitudes and practices towards Pap smear screening among male and female university students. Methods: This was a cross-sectional study that involved 416 students, carried-out from February to May 2017 among students of the University of Buea, Cameroon. Data was collected using a pretested questionnaire and analysed using Epi-Info version 7. Statistical significance was set at Pvalue <0.05. Results: The mean age of the participants was 22.08 (± 4.03) years. Up to 82.2% of participants had heard about cervical cancer. Only 25.2% of participants had “good” knowledge of cervical cancer. There was no statistically significant difference in the overall knowledge between gender (P=0.81); however, there was an association between having “good” knowledge and being a health science student (P<0.001). About two-thirds of the students knew that having multiple sexual partners was a risk factor of cervical cancer, while more than 50%, could not identify early sexual intercourse, smoking, family history, and multiple deliveries as risk factors. Only 4.8% of the female students had had a Pap smear. The low uptake was attributed to barriers: the cost of screening, lack of information on screening programs, fear, and beliefs that pap smear screening is painful. Conclusions: Knowledge of cervical cancer among university students was poor without a gender difference. Uptake of Pap smear screening was very low. We, therefore, recommend more health education and prevention programs targeting male and female students.
引言:子宫颈癌是喀麦隆第二大常见妇科恶性肿瘤,也是妇女癌症死亡的主要原因。对子宫颈癌筛查的认识和态度主要取决于性别和教育水平。Halle-Ekane et al.;岩石学报,7(4):1-11,2018;文章no.JCTI。43965 2本研究旨在了解男女大学生对宫颈癌的认知及对子宫颈抹片检查的态度和做法。方法:这是一项横断面研究,涉及416名学生,于2017年2月至5月在喀麦隆布埃亚大学的学生中进行。使用预测问卷收集数据,并使用Epi-Info version 7进行分析。p值<0.05,差异有统计学意义。结果:参与者平均年龄为22.08(±4.03)岁。高达82.2%的受访者听说过子宫颈癌。只有25.2%的受访者对子宫颈癌有“良好”的认识。性别间总体知识差异无统计学意义(P=0.81);然而,拥有“良好”知识与成为健康科学学生之间存在关联(P<0.001)。大约三分之二的学生知道有多个性伴侣是宫颈癌的危险因素,而超过50%的学生不知道过早性交、吸烟、家族史和多次分娩是危险因素。只有4.8%的女学生做过子宫颈抹片检查。低吸收率归因于障碍:筛查的成本,缺乏筛查计划的信息,恐惧,以及认为子宫颈抹片检查是痛苦的。结论:大学生对宫颈癌的认知水平较低,性别差异不大。巴氏涂片筛查的接受率非常低。因此,我们建议更多针对男女学生的健康教育和预防计划。
{"title":"Knowledge of Cervical Cancer and Its Risk Factors, Attitudes and Practices towards Pap Smear Screening among Students in the University of Buea, Cameroon","authors":"G. Halle-Ekane, Derick Nembulefack, G. E. Orock, P. N. Fon, A. Tazinya, P. Tebeu","doi":"10.9734/JCTI/2018/43965","DOIUrl":"https://doi.org/10.9734/JCTI/2018/43965","url":null,"abstract":"Introduction: Cancer of the cervix is the second most common gynaecological malignancy and the leading cause of cancer mortality among women in Cameroon. Knowledge and attitudes toward cervical cancer screening depend largely on gender and educational level. The objective of Original Research Article Halle-Ekane et al.; JCTI, 7(4): 1-11, 2018; Article no.JCTI.43965 2 this study was to determine the knowledge of cervical cancer and the attitudes and practices towards Pap smear screening among male and female university students. Methods: This was a cross-sectional study that involved 416 students, carried-out from February to May 2017 among students of the University of Buea, Cameroon. Data was collected using a pretested questionnaire and analysed using Epi-Info version 7. Statistical significance was set at Pvalue <0.05. Results: The mean age of the participants was 22.08 (± 4.03) years. Up to 82.2% of participants had heard about cervical cancer. Only 25.2% of participants had “good” knowledge of cervical cancer. There was no statistically significant difference in the overall knowledge between gender (P=0.81); however, there was an association between having “good” knowledge and being a health science student (P<0.001). About two-thirds of the students knew that having multiple sexual partners was a risk factor of cervical cancer, while more than 50%, could not identify early sexual intercourse, smoking, family history, and multiple deliveries as risk factors. Only 4.8% of the female students had had a Pap smear. The low uptake was attributed to barriers: the cost of screening, lack of information on screening programs, fear, and beliefs that pap smear screening is painful. Conclusions: Knowledge of cervical cancer among university students was poor without a gender difference. Uptake of Pap smear screening was very low. We, therefore, recommend more health education and prevention programs targeting male and female students.","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116401138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Primary Gastrointestinal Non-Hodgkin Lymphoma Diagnosed after Emergency Surgery 急诊手术后诊断的原发性胃肠道非霍奇金淋巴瘤
Pub Date : 2018-09-25 DOI: 10.9734/JCTI/2018/43771
Murat Akıcı, C. Ozdemir, M. Çilekar, R. Arslan
{"title":"Primary Gastrointestinal Non-Hodgkin Lymphoma Diagnosed after Emergency Surgery","authors":"Murat Akıcı, C. Ozdemir, M. Çilekar, R. Arslan","doi":"10.9734/JCTI/2018/43771","DOIUrl":"https://doi.org/10.9734/JCTI/2018/43771","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132298194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Intervention in Children Undergoing Chemotherapy for Cancer 儿童癌症化疗的营养干预
Pub Date : 2018-08-24 DOI: 10.9734/JCTI/2018/43197
C. Apprey, R. Annan, F. Arthur, Christopher Larbie, A. Akoto
A thesis submitted to the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology in partial fulfilment of the Requirements for the degree of DOCTOR OF PHILOSOPHY. 2015
提交给Kwame Nkrumah科技大学生物化学和生物技术系的论文,部分满足哲学博士学位的要求。2015
{"title":"Nutritional Intervention in Children Undergoing Chemotherapy for Cancer","authors":"C. Apprey, R. Annan, F. Arthur, Christopher Larbie, A. Akoto","doi":"10.9734/JCTI/2018/43197","DOIUrl":"https://doi.org/10.9734/JCTI/2018/43197","url":null,"abstract":"A thesis submitted to the Department of Biochemistry and Biotechnology, Kwame Nkrumah University of Science and Technology in partial fulfilment of the Requirements for the degree of \u0000DOCTOR OF PHILOSOPHY. 2015","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122169163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast Cancer Awareness, Knowledge and Screening Uptake among Female Secondary Schools Teachers in Owerri, Nigeria 尼日利亚奥韦里女中学教师对乳腺癌的认识、知识和筛查
Pub Date : 2018-08-20 DOI: 10.9734/jcti/2018/42635
C. Nnebue, U. Umeh, Prince Ekezie, G. Ekeh, Augustine Ekpe, Emmanuel Okodo
{"title":"Breast Cancer Awareness, Knowledge and Screening Uptake among Female Secondary Schools Teachers in Owerri, Nigeria","authors":"C. Nnebue, U. Umeh, Prince Ekezie, G. Ekeh, Augustine Ekpe, Emmanuel Okodo","doi":"10.9734/jcti/2018/42635","DOIUrl":"https://doi.org/10.9734/jcti/2018/42635","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126136711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
To Study and Compare the Relationship between Preoperative Serum TSH and Frequency of Differentiated Thyroid Cancer 探讨和比较术前血清TSH与分化型甲状腺癌发病频率的关系
Pub Date : 2018-08-09 DOI: 10.9734/JCTI/2018/42759
S. Hussain, M. Ayub, M. Kumaran, S. Vishnupriya
{"title":"To Study and Compare the Relationship between Preoperative Serum TSH and Frequency of Differentiated Thyroid Cancer","authors":"S. Hussain, M. Ayub, M. Kumaran, S. Vishnupriya","doi":"10.9734/JCTI/2018/42759","DOIUrl":"https://doi.org/10.9734/JCTI/2018/42759","url":null,"abstract":"","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114168585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Chemoports in a Comprehensive Cancer Care Center, a Retrospective Study 综合癌症护理中心化疗方案的回顾性研究
Pub Date : 2018-07-16 DOI: 10.9734/JCTI/2018/42732
M. Pattanayak, A. Arora, S. Saini, A. Gaind, U. Baruah, S. Verma, Meenu Gupta
Aim of the Study: Treatment protocols that use intravenous cytotoxic agents need long term access to large veins, that can be maintained for a prolonged period in a sterile way. Use of implantable devices for this purpose have become the preferred choice these days, but they have their own set of problem s, starting from difficulties in cannulation to safely maintaining the access for a prolonged period of time in a sterile way. Moreover, the patient population undergoing these treatments are mostly immunosuppressed and prone to systemic infections making the care of any Original Research Article Pattanayak et al.; JCTI, 7(3): 1-8, 2018; Article no.JCTI.42732 2 implanted device more difficult. The present study evaluates the experience of using chemoports in a comprehensive cancer care center. Subjects and Methods: We retrospectively reviewed our experience in handling Chemoports inserted at our own hospital over a period of three years, as regards to difficulties during insertion and during administration of venotoxic agents. All patients who were advised more than 4 cycles of cytotoxic drugs were included and approval of the university research and ethics committee was taken prior to data analysis. Results: Retrospective data of a total of 120 chemoports was evaluated for the study. The most common malignancy was breast cancer, and the commonest chemotherapeutic regimen was Adriamycin/Epirubicin and Cyclophosphamide followed by Taxanes. The preferred site of insertion was right subclavian vein in 52.5% of cases. The average time taken for the procedure ranged from 25 mins to 2 hrs. Procedural difficulties were documented in 48 [40%] insertions, the most common being multiple punctures for venous access. 3 patients developed hematoma during the procedure and, one patient had puncture of carotid artery. Passage of the catheter to the opposite jugular vein was an interesting happening and occurred in 3 patients. None of the patients who had subclavian vessel cannulation had pneumothorax. All the complications were managed conservatively. The median days of catheter life was 265 days. In the follow up period 30 patients [25%] had events related to difficulty of use and port related infection,12 patients had difficulties in canulation of the Chemo port reservoir and 6 Ports could not be used for further chemotherapy and were removed. Infectious complications were seen in 12 ports, the commonest being pocket site infection. We had a policy of recommending removal of the chemoport 6 months after completion of the planned chemotherapy protocol or 2 years after placement of the port, whichever is earlier. At the end of the study period, 47 of the patients had their chemoports removed, 10 patients were lost to follow up and hopefully got the devices removed elsewhere. Conclusion: The present day chemoports are simple to insert, and easy to manage with proper asepsis expected in an immunosupressed patient. However, a dedicated team of trained personnel vi
研究目的:使用静脉注射细胞毒性药物的治疗方案需要长期进入大静脉,这可以在无菌方式下维持较长时间。使用植入式装置来实现这一目的已成为目前的首选,但它们也有自己的一系列问题,从插管困难到以无菌方式长时间安全维持通道。此外,接受这些治疗的患者群体大多免疫抑制,容易发生全身性感染,这使得任何原始研究文章的护理Pattanayak等人;岩石学报,7(3):1-8,2018;文章no.JCTI。42732植入器械比较困难。本研究评估在综合癌症护理中心使用化疗机会的经验。对象和方法:我们回顾性地回顾了我们在本院近三年来处理化学插孔插入的经验,包括在插入和静脉毒性药物施用过程中遇到的困难。所有建议使用细胞毒性药物超过4个周期的患者均纳入研究,并在数据分析前获得大学研究和伦理委员会的批准。结果:本研究对120例化疗患者的回顾性数据进行了评估。最常见的恶性肿瘤是乳腺癌,最常见的化疗方案是阿霉素/表柔比星和环磷酰胺,其次是紫杉烷。52.5%的患者优先选择右锁骨下静脉。手术的平均时间从25分钟到2小时不等。在48例(40%)插入中记录了操作困难,最常见的是多次穿刺静脉通路。术中出现血肿3例,颈动脉穿刺1例。导管通过颈静脉对面是一个有趣的现象,发生在3例患者中。锁骨下血管插管的患者均无气胸。所有并发症均予保守处理。导管寿命中位数为265天。随访期间,30例(25%)患者出现使用困难和端口相关感染事件,12例患者出现Chemo端口储液困难,6例患者因无法继续化疗而被切除。感染并发症出现在12个端口,最常见的是口袋部位感染。我们的政策建议在完成计划的化疗方案6个月后或放置化疗端口2年后取出化疗端口,以较早者为准。在研究期结束时,47名患者移除了他们的化学端口,10名患者失去了随访,希望他们在其他地方移除了设备。结论:对于免疫抑制的患者,目前的化疗孔插入简单,易于操作,并可进行适当的无菌处理。但是,需要一支由外科医生、麻醉师、临床肿瘤学家和护理人员组成的专业团队,以便将与这些设备相关的并发症降至最低。这在资源贫乏的国家也很重要,因为这些昂贵的装置很难开处方,所以一旦插入,它们可以持续到化疗结束。
{"title":"Use of Chemoports in a Comprehensive Cancer Care Center, a Retrospective Study","authors":"M. Pattanayak, A. Arora, S. Saini, A. Gaind, U. Baruah, S. Verma, Meenu Gupta","doi":"10.9734/JCTI/2018/42732","DOIUrl":"https://doi.org/10.9734/JCTI/2018/42732","url":null,"abstract":"Aim of the Study: Treatment protocols that use intravenous cytotoxic agents need long term access to large veins, that can be maintained for a prolonged period in a sterile way. Use of implantable devices for this purpose have become the preferred choice these days, but they have their own set of problem s, starting from difficulties in cannulation to safely maintaining the access for a prolonged period of time in a sterile way. Moreover, the patient population undergoing these treatments are mostly immunosuppressed and prone to systemic infections making the care of any Original Research Article Pattanayak et al.; JCTI, 7(3): 1-8, 2018; Article no.JCTI.42732 2 implanted device more difficult. The present study evaluates the experience of using chemoports in a comprehensive cancer care center. Subjects and Methods: We retrospectively reviewed our experience in handling Chemoports inserted at our own hospital over a period of three years, as regards to difficulties during insertion and during administration of venotoxic agents. All patients who were advised more than 4 cycles of cytotoxic drugs were included and approval of the university research and ethics committee was taken prior to data analysis. Results: Retrospective data of a total of 120 chemoports was evaluated for the study. The most common malignancy was breast cancer, and the commonest chemotherapeutic regimen was Adriamycin/Epirubicin and Cyclophosphamide followed by Taxanes. The preferred site of insertion was right subclavian vein in 52.5% of cases. The average time taken for the procedure ranged from 25 mins to 2 hrs. Procedural difficulties were documented in 48 [40%] insertions, the most common being multiple punctures for venous access. 3 patients developed hematoma during the procedure and, one patient had puncture of carotid artery. Passage of the catheter to the opposite jugular vein was an interesting happening and occurred in 3 patients. None of the patients who had subclavian vessel cannulation had pneumothorax. All the complications were managed conservatively. The median days of catheter life was 265 days. In the follow up period 30 patients [25%] had events related to difficulty of use and port related infection,12 patients had difficulties in canulation of the Chemo port reservoir and 6 Ports could not be used for further chemotherapy and were removed. Infectious complications were seen in 12 ports, the commonest being pocket site infection. We had a policy of recommending removal of the chemoport 6 months after completion of the planned chemotherapy protocol or 2 years after placement of the port, whichever is earlier. At the end of the study period, 47 of the patients had their chemoports removed, 10 patients were lost to follow up and hopefully got the devices removed elsewhere. Conclusion: The present day chemoports are simple to insert, and easy to manage with proper asepsis expected in an immunosupressed patient. However, a dedicated team of trained personnel vi","PeriodicalId":161223,"journal":{"name":"Journal of Cancer and Tumor International","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121847977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Cancer and Tumor International
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1