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Considering the ethics of live tissue training in trauma surgery. 创伤外科活体组织训练的伦理思考。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-14 DOI: 10.1136/jme-2023-109761
Cara Swain, Rory Rickard, Klas Karlgren, Gert Helgesson

'Live tissue training', using an anaesthetised live animal substituted for a human patient for the practice of surgical skills, is a controversial topic. Although simulator technologies have developed significantly for inclusion in many areas of surgical education, it is contested that training to manage traumatic injuries requires a model that can bleed and has a dynamic circulation. This article uses the published literature to explore the values at stake regarding live tissue training in the context of trauma with the aim of considering whether such training is ethically justifiable, to any degree. We present criteria for the ethical evaluation of live animal use in trauma simulation alongside descriptions of the pro- and contra-arguments present in the literature. Our conclusion is that justification is challenging and must be considered on a case-by-case basis-it is important that the difference gained from using a live animal compared with the best alternative simulator has to be greater than the clear ethical downside of using animals.

“活体组织训练”是指用麻醉过的活体动物代替人类患者进行手术技巧练习,这是一个有争议的话题。尽管模拟器技术已经在外科教育的许多领域得到了显著的发展,但对于创伤性损伤管理的培训需要一个可以流血和具有动态循环的模型,这是有争议的。本文利用已发表的文献来探讨在创伤背景下进行活体组织训练的价值,目的是考虑这种训练在任何程度上是否在道德上是合理的。我们提出了在创伤模拟中使用活体动物的伦理评估标准,以及文献中存在的赞成和反对观点的描述。我们的结论是,理由是具有挑战性的,必须在个案的基础上考虑——重要的是,与最好的替代模拟器相比,使用活体动物获得的差异必须大于使用动物的明显的道德缺点。
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引用次数: 0
Chat-IRB? How application-specific language models can enhance research ethics review. Chat-IRB吗?应用特定语言模型如何加强研究伦理审查。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-14 DOI: 10.1136/jme-2025-110845
Sebastian Porsdam Mann, Jiehao Joel Seah, Stephen Latham, Julian Savulescu, Mateo Aboy, Brian D Earp

Institutional review boards (IRBs) play a crucial role in ensuring the ethical conduct of human subjects research, but face challenges including inconsistency, delays, and inefficiencies. We propose the development and implementation of application-specific large language models (LLMs) to facilitate IRB review processes. These IRB-specific LLMs would be fine-tuned on IRB-specific literature and institutional datasets, and equipped with retrieval capabilities to access up-to-date, context-relevant information. We outline potential applications, including pre-review screening, preliminary analysis, consistency checking, and decision support. While addressing concerns about accuracy, context sensitivity, and human oversight, we acknowledge remaining challenges such as over-reliance on artificial intelligence and the need for transparency. By enhancing the efficiency and quality of ethical review while maintaining human judgement in critical decisions, IRB-specific LLMs offer a promising tool to improve research oversight. We call for pilot studies to evaluate the feasibility and impact of this approach.

机构审查委员会(IRBs)在确保人类受试者研究的伦理行为方面发挥着至关重要的作用,但面临着包括不一致、延迟和效率低下在内的挑战。我们建议开发和实现特定于应用程序的大型语言模型(llm),以促进IRB审查过程。这些irb特定的法学硕士将根据irb特定的文献和机构数据集进行微调,并配备检索功能,以访问最新的、与上下文相关的信息。我们概述了潜在的应用,包括预审查筛选,初步分析,一致性检查和决策支持。在解决对准确性、上下文敏感性和人为监督的担忧的同时,我们承认仍然存在的挑战,如过度依赖人工智能和对透明度的需求。通过提高伦理审查的效率和质量,同时在关键决策中保持人类的判断,irb特定的法学硕士提供了一个有前途的工具来改善研究监督。我们呼吁进行试点研究,以评估这种做法的可行性和影响。
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引用次数: 0
Harms of the current global anti-FGM campaign. 当前全球反女性生殖器切割运动的危害。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-14 DOI: 10.1136/jme-2025-110961
Fuambai Sia Nyoko Ahmadu, Dina Bader, Janice Boddy, Mamasa Camara, Natasha Carver, Rosie Duivenbode, Brian D Earp, Birgitta Essén, Ellen Gruenbaum, Saida Hodžić, Sara Johnsdotter, Saffron Karlsen, Sophia Koukoui, Cynthia Kraus, MariaCaterina La Barbera, Lori Leonard, Carlos D Londoño Sulkin, Ruth M Mestre I Mestre, Sarah O'Neill, Christina Pantazis, Maree Pardy, Juliet Rogers, Nan Seuffert, Arianne Shahvisi, Richard A Shweder, Lotta Wendel

Traditional female genital practices, though long-standing in many cultures, have become the focus of an expansive global campaign against 'female genital mutilation' (FGM). In this article, we critically examine the harms produced by the anti-FGM discourse and policies, despite their grounding in human rights and health advocacy. We argue that a ubiquitous 'standard tale' obscures the diversity of practices, meanings and experiences among those affected. This discourse, driven by a heavily racialised and ethnocentric framework, has led to unintended but serious consequences: the erosion of trust in healthcare settings, the silencing of dissenting or nuanced community voices, racial profiling and disproportionate legal surveillance of migrant families. Moreover, we highlight a troubling double standard that legitimises comparable genital surgeries in Western contexts while condemning similar procedures in others. We call for more balanced and evidence-based journalism, policy and public discourse-ones that account for cultural complexity and avoid the reductive and stigmatising force of the term 'mutilation'. A re-evaluation of advocacy strategies is needed to ensure that they do not reproduce the very injustices they aim to challenge.

传统的女性生殖器习俗虽然在许多文化中由来已久,但已成为广泛的全球反对“切割女性生殖器”运动的焦点。在本文中,我们批判性地审视了反女性生殖器切割的话语和政策所产生的危害,尽管它们基于人权和健康倡导。我们认为,无处不在的“标准故事”掩盖了受影响者的实践、意义和经验的多样性。在严重种族化和种族中心主义框架的推动下,这种话语导致了意想不到但严重的后果:对医疗机构的信任受到侵蚀,不同意见或细微差别的社区声音被压制,种族貌相以及对移民家庭的不成比例的法律监督。此外,我们强调了一种令人不安的双重标准,即在西方背景下合法化类似的生殖器手术,同时谴责其他国家的类似手术。我们呼吁建立更加平衡和基于证据的新闻、政策和公共话语,这些新闻、政策和公共话语应考虑到文化的复杂性,并避免“残害”一词的贬低和污名化力量。需要重新评价宣传战略,以确保它们不会重现它们旨在挑战的不公正现象。
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引用次数: 0
Just culture as dialogical learning: theoretical foundations and practical implications of restorative justice. 作为对话学习的公正文化:恢复性司法的理论基础与实践意义。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-14 DOI: 10.1136/jme-2025-110761
Eva van Baarle, Guy Widdershoven, Bert Molewijk

Just culture is a recent perspective on responding to accidents or incidents in organisations. It refers to the importance of doing justice to the situation and the people involved, aimed at strengthening safety in the workplace and preventing future harm. There are two main conceptualisations of just culture, implying different views on justice, namely retributive and restorative justice. The concept of retributive justice emphasises individual responsibility for failures and the enforcement of given norms about right vs wrong via sanctions and punishment. Restorative justice emphasises the systemic and cultural dimension of accidents or incidents and aims to foster learning conditions for groups as well as the organisation involved. Elaborating on the theoretical presuppositions of the concept is important, both for theorising about just culture and for fostering just culture in practice. We extend the literature by looking into two approaches in contemporary philosophy and ethics that can deepen our understanding of what a restorative approach to just culture entails and how to foster it in practice: dialogical hermeneutics and care ethics. We show that dialogical hermeneutics and care ethics enable us to specify repair as a relational practice, understanding as an interpretation of the situation and identification of needs and moral learning as dialogical and democratic processes of joint reflection. By providing a concrete example of fostering restorative justice in a healthcare organisation, we demonstrate how the theoretical characteristics of a restorative justice inspired by dialogical hermeneutics and care ethics can be translated into practical processes of organisational moral learning.

Just culture是组织中应对事故或事件的最新视角。它指的是公正对待所涉及的情况和人员的重要性,旨在加强工作场所的安全,防止未来的伤害。正义文化有两种主要的概念,暗示着对正义的不同看法,即报复性正义和恢复性正义。报复性正义的概念强调个人对失败的责任,并通过制裁和惩罚来执行关于对与错的既定规范。恢复性司法强调事故或事件的系统和文化层面,旨在为相关团体和组织创造学习条件。阐述这一概念的理论前提是很重要的,无论是对公正文化的理论建构,还是在实践中培育公正文化。我们通过研究当代哲学和伦理学中的两种方法来扩展文献,这两种方法可以加深我们对正义文化的恢复性方法的理解,以及如何在实践中培养它:对话解释学和关怀伦理学。我们表明,对话解释学和关怀伦理学使我们能够将修复指定为一种关系实践,将理解指定为对情况的解释,将需求的识别和道德学习指定为共同反思的对话和民主过程。通过提供一个在医疗保健组织中培养恢复性正义的具体例子,我们展示了由对话解释学和护理伦理学启发的恢复性正义的理论特征如何可以转化为组织道德学习的实践过程。
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引用次数: 0
Why pregnancy is not a disease: a critique from the perspective of biological trade-offs. 为什么怀孕不是一种疾病:从生物权衡角度的批评。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-09 DOI: 10.1136/jme-2025-111409
Xueshi Wang

This paper aims to critique the argument constructed by Anna Smajdor and Joona Räsänen that pregnancy is a disease. Their argument that pregnancy fits the features of disease they enumerate stems from an analysis based on an ontological framework I term the 'logic of the list'. This framework fails to grasp the essential and pervasive nature of the biological trade-offs that characterise complex phenomena like pregnancy. This paper argues that the generative logic behind many of the negative features of pregnancy differs significantly from that of true pathological processes. They are not signs of pathological dysregulation, but rather the structural costs that a complex adaptive system must pay in its process of reproduction.

本文旨在批判Anna Smajdor和Joona Räsänen提出的怀孕是一种疾病的观点。他们认为怀孕符合他们列举的疾病的特征,这一论点源于一种基于我称之为“清单逻辑”的本体论框架的分析。这一框架未能把握作为怀孕等复杂现象特征的生物权衡的本质和普遍本质。本文认为,怀孕的许多负面特征背后的生成逻辑明显不同于真正的病理过程。它们不是病理性失调的迹象,而是一个复杂的适应系统在繁殖过程中必须付出的结构性代价。
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引用次数: 0
Caution before condemnation: rethinking responsibility for Gaza's healthcare scarcity. 谴责前的谨慎:重新思考加沙医疗短缺的责任。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-09 DOI: 10.1136/jme-2025-111392
Simon Lucas

In a recent exchange in this journal on responsibility for healthcare scarcity in Gaza, McMahan argues that bioethicists should unconditionally condemn Hamas yet insists that the group's actions do not diminish the protections owed to civilians. He further argues that Israel bears the greatest responsibility for civilian suffering, having violated the principles of proportionality, necessity and discrimination. On this basis, he maintains that while all parties must be held accountable for breaches of ethical and humanitarian norms, Israel's conduct should be condemned as unjust, impermissible and as carrying the primary burden of responsibility. In this response, I argue that McMahan's position suffers from several shortcomings: it relies on controversial sources while not engaging with credible alternatives, and it privileges a particular strand of just war theory while failing to present alternative frameworks, many of which are likely unfamiliar to bioethicists. This is unsurprising, given that McMahan has developed one of the most influential contemporary theories of just war. Nevertheless, if bioethicists are to issue judgements on the allocation of responsibility in armed conflict and to condemn the conduct of warring parties, they would be better equipped to do so through rigorous engagement with the full range of available evidence and through measured consideration of the diverse ethical frameworks that govern war and armed conflict.

在本刊最近关于加沙医疗短缺责任的交流中,麦克马汉认为,生物伦理学家应该无条件谴责哈马斯,但坚持认为该组织的行为不会减少对平民的保护。他进一步争辩说,以色列对平民的苦难负有最大的责任,因为它违反了相称性、必要性和歧视原则。在此基础上,他坚持认为,虽然所有各方都必须对违反道德和人道主义准则的行为负责,但以色列的行为应被谴责为不公正、不允许和承担主要责任的行为。在这个回应中,我认为麦克马汉的立场有几个缺点:它依赖于有争议的来源,而没有参与可信的替代方案,它特权于正义战争理论的特定分支,而未能提出替代框架,其中许多可能对生物伦理学家来说是不熟悉的。考虑到麦克马汉提出了当代最有影响力的正义战争理论之一,这并不奇怪。尽管如此,如果生物伦理学家要对武装冲突中的责任分配做出判断,并谴责交战各方的行为,他们将更好地通过对所有可用证据的严格接触,并通过对管理战争和武装冲突的各种道德框架的慎重考虑来做到这一点。
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引用次数: 0
Against the biological account of death. 反对死亡的生物学解释
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-04 DOI: 10.1136/jme-2025-111572
Lane Taylor

Julian Kanu has recently defended a pro-life perspective on abortion by arguing for a novel theory of the badness of death called the biological account of death (BAD). BAD is a deprivationist account similar to Jeff McMahan's time relative interest account (TRIA). Kanu argues that BAD explains our intuitions about the badness of death as well as TRIA, except in one special case regarding a comatose infant. In this case, BAD accommodates our intuition that such an infant would be seriously harmed by death, but TRIA does not. All else being equal, BAD is a better theory than TRIA. I argue that not all is equal between the two theories; TRIA accommodates intuitions that BAD cannot, and there is reason to doubt our intuitions regarding the comatose infant.

朱利安·卡努(Julian Kanu)最近为反对堕胎的观点辩护,他提出了一种关于死亡坏处的新理论,叫做“死亡的生物学解释”(BAD)。BAD是一个类似于Jeff McMahan的时间相对利息账户(TRIA)的剥夺主义账户。卡努认为,除了一个关于昏迷婴儿的特殊情况外,BAD解释了我们对死亡坏处的直觉,也解释了TRIA。在这种情况下,BAD符合我们的直觉,即这样的婴儿会因死亡而受到严重伤害,但TRIA则不然。在其他条件相同的情况下,BAD理论比TRIA更好。我认为这两种理论并非完全相同;TRIA能适应BAD不能适应的直觉,我们有理由怀疑我们对昏迷婴儿的直觉。
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引用次数: 0
Organ markets are always the best option. 器官市场永远是最好的选择。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-12-04 DOI: 10.1136/jme-2025-111578
Perry Hendricks

The world faces an organ shortage, resulting in thousands of deaths each year. By allowing organ markets, we could increase the supply of organs, thereby saving many lives and enriching many organ sellers. One defence of organ markets points out that by prohibiting them, we are taking away what would-be organ sellers regard as their best option, and we thus doom them to stay in their dire circumstances. However, we should not take away what people regard as their best option, and hence we should not prohibit organ markets. Andreas Albersen claims this argument fails because justice requires we offer would-be organ sellers an even better option. However, I show that organ markets are always the best option.

世界面临器官短缺,每年导致数千人死亡。通过允许器官市场,我们可以增加器官供应,从而挽救许多生命,并使许多器官销售商发财。一个为器官市场辩护的人指出,通过禁止器官市场,我们剥夺了潜在器官卖家认为的最佳选择,因此我们注定了他们将继续处于悲惨的境地。然而,我们不应该剥夺人们认为他们最好的选择,因此我们不应该禁止器官市场。安德里亚斯·艾伯森声称,这一论点站不住脚,因为正义要求我们为潜在的器官卖家提供更好的选择。然而,我认为器官市场永远是最好的选择。
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引用次数: 0
Beyond relationalism: distinguishing moral and legal personhood after Jecker and Atuire. 超越关系主义:在杰克和阿图尔之后区分道德人格和法律人格。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-11-28 DOI: 10.1136/jme-2025-111520
Johnny Sakr

In their recent Authors Meet Critics contribution to the Journal of Medical Ethics, Nancy S Jecker and Caesar Alimsinya Atuire invite a re-examination of personhood that extends beyond Western individualism and incorporates relational, cross-cultural insights. Their account effectively recentres moral discourse on community, continuity and mutual recognition. This response agrees with Jecker and Atuire that personhood cannot be reduced to autonomy or cognitive capacity alone, but it argues that a further conceptual distinction is needed to preserve clarity between moral and institutional recognition.I propose a dual-layered framework of personhood. The metaphysical person is the enduring subject of moral concern whose identity persists through time, relation and narrative; the legal person is the socially constructed bearer of rights and duties recognised within juridical and political systems. While the two frequently overlap, conflating them risks conceptual ambiguity and ethical inconsistency, particularly in cases such as dementia, embryonic life and artificial intelligence.Jecker and Atuire's relational model richly captures the metaphysical dimension of personhood but leaves open the question of how legal and moral status diverge and interact. The proposed two-layer approach clarifies this interface: moral personhood provides grounding for respect and care, while legal personhood institutionalises those obligations within normative systems. Recognising these distinct yet complementary layers retains Jecker and Atuire's relational insights while safeguarding conceptual precision across diverse bioethical contexts.

Nancy S . Jecker和Caesar Alimsinya Atuire最近在《医学伦理学杂志》(Journal of Medical Ethics)上发表的《作者与评论家的相遇》(Authors Meet Critics)一文中,邀请人们重新审视超越西方个人主义的人格,并将关系和跨文化的见解结合起来。他们的描述有效地将道德话语集中在社区、连续性和相互承认上。这一回应同意Jecker和Atuire的观点,即人格不能仅仅被简化为自主性或认知能力,但它认为,需要进一步的概念区分,以保持道德和制度认可之间的清晰性。我提出了一个双重人格框架。形而上的人是道德关怀的永恒主体,其身份在时间、关系和叙事中持续存在;法人是社会建构的权利和义务的承担者,在法律和政治制度中得到承认。虽然这两者经常重叠,但将它们混为一谈可能会导致概念模糊和伦理不一致,尤其是在痴呆症、胚胎生命和人工智能等情况下。Jecker和Atuire的关系模型丰富地抓住了人格的形而上维度,但留下了法律和道德地位如何分化和相互作用的问题。拟议的双层方法澄清了这一界面:道德人格为尊重和关怀提供了基础,而法律人格则在规范体系内将这些义务制度化。认识到这些不同而又互补的层面,既保留了Jecker和Atuire的关系洞察力,又保证了不同生物伦理背景下概念的准确性。
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引用次数: 0
Between intention and side effect: evaluation of consciousness diminution under the doctrine of double effect. 意图与副作用之间:双重效应理论下意识削弱的评价。
IF 3.4 2区 哲学 Q1 ETHICS Pub Date : 2025-11-27 DOI: 10.1136/jme-2025-111391
Christos Lazaridis
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引用次数: 0
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Journal of Medical Ethics
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