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An Unaccustomed Presentation of Besnier-Boeck-Schaumann Disease 贝斯尼尔-博克-肖曼病的非惯常表现
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.11
Dr Vani Raj I
Eliminating other potential causes of granulomatous inflammation helps to diagnose the mysterious sarcoidosis. All clinicians face a diagnostic dilemma because of the clinical polymorphism and the multisystemic sarcoidosis symptoms. After the lungs, the skin is the organ most frequently impacted by sarcoidosis. Before, during, or after systemic involvement, dermatological symptoms can occur, and the kind of skin lesion can have a bearing on the prognosis. Additionally, compared to a biopsy of visceral organs, a skin lesion biopsy is easier to perform and less intrusive. Therefore, there are some instances in which cutaneous symptoms can help with the diagnosis and outlook of a systemic illness. A high index of clinical suspicion is needed for early diagnosis and timely management, which can improve the quality of life for those patients and reduce morbidy and mortality due to this disease. This article has emphasised the prevalence, clinical characteristics, and treatment of the common skin lesions of sarcoidosis.
排除肉芽肿性炎症的其他潜在病因有助于诊断神秘的肉样瘤病。由于临床多态性和多系统肉样瘤病症状,所有临床医生都面临着诊断难题。皮肤是继肺部之后最常受肉样瘤病影响的器官。在全身受累之前、期间或之后,都可能出现皮肤症状,而皮肤病变的类型会对预后产生影响。此外,与内脏器官活检相比,皮肤病变活检更容易进行,侵犯性也更小。因此,在某些情况下,皮肤症状有助于诊断和展望全身性疾病。临床上需要高度怀疑,以便早期诊断和及时处理,这可以提高患者的生活质量,降低该疾病的发病率和死亡率。本文重点介绍了肉样瘤病常见皮肤病变的发病率、临床特点和治疗方法。
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引用次数: 0
Giant Chorioangioma in a Patient with 36 Weeks of Pregnancy: A Case Report 妊娠 36 周患者的巨大绒毛膜血管瘤:病例报告
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.04
B. Mehrotra
Abstract Present report relates to a 40-year-old patient with 36 weeks of pregnancy and non-trophoblastic benign placental neoplasm chorioangioma (placental hemangioma). The incidence of chorioangioma has been described as 0.5 to 1.0 % of all pregnancies. Tumors may be >4 cm in diameter; such tumors are called giant tumors. Smaller tumors are generally asymptomatic. However, clinically-significant chorioangioma occur less frequently; incidence varying from 1 in 3500 to 1 in 9000 pregnancies. Giant chorioangiomas are very rare tumors; only a few cases have been reported. Feto-maternal complications like fetal growth retardation, anemia and hydrops may develop in a patient with chorioangioma. Further, fetal loss may be as high as ~ 40 %. Increased incidence of chorioangiomas may occur at high-altitude pregnancies, suggesting role of hypobaric hypoxia in pathogenesis of chorioangioma. Keywords: Well-circumscribed benign placental neoplasm.
摘要 本报告涉及一名妊娠 36 周、非滋养细胞胎盘良性肿瘤绒毛膜血管瘤(胎盘血管瘤)的 40 岁患者。据描述,绒毛血管瘤的发病率占所有妊娠的 0.5%至 1.0%。肿瘤直径可能大于 4 厘米,这种肿瘤被称为巨大肿瘤。较小的肿瘤一般没有症状。然而,有临床意义的绒毛膜血管瘤发生率较低;发生率从每 3500 例妊娠中 1 例到每 9000 例妊娠中 1 例不等。巨大绒毛膜血管瘤是非常罕见的肿瘤,仅有几例报道。绒毛膜血管瘤患者可能会出现胎儿发育迟缓、贫血和肾积水等母胎并发症。此外,胎儿丢失率可能高达 40%。高海拔地区妊娠可能会增加绒毛膜血管瘤的发病率,这表明低压缺氧在绒毛膜血管瘤的发病机制中起着重要作用。关键词圆形胎盘良性肿瘤。
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引用次数: 0
Graded Epidural Anaesthesia as a Sole Anaesthetic Technique for Lower Limb Surgeries in Patients with Low Ejection Fraction: A Case Series 将硬膜外分级麻醉作为低射血分数患者下肢手术的唯一麻醉技术:病例系列
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.18
Dr Anu Ambooken MD, FICM
In patients with a history of ischemic heart disease with low ejection fraction, it’s always a challenge for the Anaesthesiologist to make a decision on whether to administer General Anaesthesia (GA), central neuraxial blockade, or both. When the Left ventricular ejection fraction (LVEF) percentage reduces to less than 35%, it indicates the presence of severe systolic dysfunction. Both general anaesthesia and regional anaesthesia carry potential risks due to these patients' low cardiac output status. Hemodynamic fluctuations associated with anaesthesia can be detrimental in these patients. A clear intraoperative plan should be designed to manage the hemodynamics of these patients. Here we report two cases of ischemic heart disease with low ejection fraction posted for orthopedic surgeries. Graded epidural anaesthesia was used as a sole anaesthetic technique. The patients were hemodynamically stable in the intraoperative as well as postoperative period. Keywords: Ischemic heart disease, Low Left Ventricular Ejection Fraction, Graded Epidural Anaesthesia, Cemented modular hemiarthroplasty, PFNA2.
对于有低射血分数缺血性心脏病病史的患者,麻醉医生在决定是实施全身麻醉(GA)、中枢神经阻滞还是两者兼用时总是面临挑战。当左心室射血分数(LVEF)百分比降至 35% 以下时,表明存在严重的收缩功能障碍。由于这些患者的心输出量较低,全身麻醉和区域麻醉都存在潜在风险。麻醉引起的血流动力学波动会对这些患者造成损害。应制定明确的术中计划来管理这些患者的血流动力学。在此,我们报告了两例因骨科手术而住院的低射血分数缺血性心脏病患者。分级硬膜外麻醉是唯一的麻醉技术。患者术中和术后血流动力学稳定。关键词缺血性心脏病 低左室射血分数 硬膜外分级麻醉 骨水泥组合半关节成形术 PFNA2
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引用次数: 0
Application Nanobiotech in Neurodegenerative Diseases 纳米生物技术在神经退行性疾病中的应用
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.12
Tukur Zayyanu
Background: An early pathogenic role for mitochondrial dysfunction in affected neurons, which occurs before morphological and functional abnormalities, is being supported by expanding information from studies on neurodegenerative diseases. Age is the primary risk factor for numerous diseases that affect people, the degenerative disorders are characterized by an abnormal protein accumulation, progressive loss of neuron cells, and impaired motor or cognitive abilities. One of the fundamental characteristics of aging is mitochondrial malfunction, especially in organs that need a lot of energy, such the heart, muscles, brain, or liver. Small amounts of ROS are produced by natural cell functions such aerobic respiration and inflammatory response mostly in macrophages and hepatocytes.
背景:神经退行性疾病研究的更多信息支持线粒体功能障碍在受影响神经元中的早期致病作用,这种作用发生在形态和功能异常之前。年龄是影响人类的多种疾病的主要风险因素,退行性疾病的特点是蛋白质异常积累、神经元细胞逐渐丧失以及运动或认知能力受损。衰老的基本特征之一是线粒体功能失调,尤其是在需要大量能量的器官中,如心脏、肌肉、大脑或肝脏。细胞的自然功能(如有氧呼吸和炎症反应)会产生少量的 ROS,主要是在巨噬细胞和肝细胞中。
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引用次数: 0
Rare Neurological Manifestation of Thyroid Disorders – An Interesting Case Series 甲状腺疾病的罕见神经系统表现--有趣的病例系列
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.03
Jenix Nathan, Shobana N, Sacratis
Background & Aims Disorders of thyroid gland are among the most common endocrine disorder. The neurologic disorders associated with thyroid dysfunction span the entire spectrum of neurology. Symptoms range from disorders of emotion and higher cognitive function to movement disorders, neuromuscular diseases and a range of rarer yet significant neurologic sequalae. Myopathy is the most common of the peripheral neurologic manifestations in both hypothyroidism and hyperthyroidism. Compressive mononeuropathies, namely carpal tunnel syndrome, are a major feature in hypothyroidism. At the level of the central nervous system, psychosis, personality change, mood disorder, confusion, dementia, coma, and seizures can occur in either hypothyroidism or hyperthyroidism. Movement disorders occur in hyperthyroidism, whereas ataxia and headaches are associated with hypothyroidism.
背景与目的 甲状腺疾病是最常见的内分泌疾病之一。与甲状腺功能障碍相关的神经系统疾病横跨整个神经病学领域。症状包括情感障碍、高级认知功能障碍、运动障碍、神经肌肉疾病以及一系列罕见但严重的神经系统后遗症。肌病是甲状腺功能减退症和甲状腺功能亢进症最常见的周围神经表现。压迫性单神经病变,即腕管综合征,是甲状腺功能减退症的主要特征。在中枢神经系统方面,甲减和甲亢都可能出现精神病、人格改变、情绪障碍、意识模糊、痴呆、昏迷和癫痫发作。甲状腺功能亢进症会出现运动障碍,而共济失调和头痛则与甲状腺功能减退症有关。
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引用次数: 0
Multiple Sinuses around Umbilical Port Site due to Atypical Mycobacterium after Laparoscopic Cholecystectomy- A Rare Case Report 腹腔镜胆囊切除术后非典型分枝杆菌导致的脐孔周围多发窦道--罕见病例报告
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.15
Vidit Sandeep Verma
Uncommon surgical site infection following laparoscopic cholecystectomy characterized by port site tuberculosis caused by atypical mycobacterium or non tubercular mycobacterium. This infection exhibited an atypical pattern spread of infection occurs within subcutaneous plane and leading to the formation of multiple abscesses and sinuses. Comprehensive management approach by surgical intervention by drainage and debridement of the affected area and long- term multidrug anti-tubercular therapy, resulting in complete healing of the sinuses. This case report highlights the importance of considering atypical pathogens in the differential diagnosis of surgical site infection and comprehensive management strategy. Keywords: Atypical Mycobacterium, Tuberculosis, Multiple sinuses, Anterior abdominal wall, Laparoscopic cholecystectomy
腹腔镜胆囊切除术后的罕见手术部位感染,其特征是由非典型分枝杆菌或非结核分枝杆菌引起的端口部位结核。这种感染表现出非典型模式,感染在皮下平面扩散,导致形成多个脓肿和窦道。通过外科手术对患处进行引流和清创,并长期使用多种药物进行抗结核治疗,最终鼻窦完全愈合。本病例报告强调了在手术部位感染的鉴别诊断和综合治疗策略中考虑非典型病原体的重要性。关键词:非典型分枝杆菌非典型分枝杆菌 结核病 多发性窦道 前腹壁 腹腔镜胆囊切除术
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引用次数: 0
Barriers and Challenges to Adopting Telemedicine in Saudi Arabia: A Systematic Review 沙特阿拉伯采用远程医疗的障碍和挑战:系统回顾
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.16
Dr Anfal Mohammed Aljohani
Background: Telemedicine involves the use of information technology in the delivery of healthcare services. The implementation of telemedicine has increased recently, especially during the COVID-19 pandemic period. There are many barriers to the adoption of telemedicine. Additionally, these barriers showed little focus, and studies didn't specify a great focus on such barriers in Saudi Arabia. Aim: To assess the barriers and challenges restricting the adoption of telemedicine in Saudi Arabia by reviewing the previous studies conducted on this subject.
背景:远程医疗涉及在提供医疗保健服务时使用信息技术。远程医疗的实施近来有所增加,尤其是在 COVID-19 大流行期间。采用远程医疗有许多障碍。此外,这些障碍很少受到关注,沙特阿拉伯的研究也没有明确指出这些障碍。目的:通过回顾之前就该主题开展的研究,评估沙特阿拉伯在采用远程医疗方面遇到的障碍和挑战。
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引用次数: 0
Circumcision by plastibell technique: Boon for Low Income Countries (LIC) - A Case Series 包皮环切术:低收入国家(LIC)的福音--一个案例系列
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.10
Dr Kush Jhunjhunwala
Introduction: Circumcision is a religious practice as well as a surgical procedure having its risks and benefits. There are several surgical methods for circumcision. The choice depends on skill and preference of medical personnel performing the surgery. The plastibell technique is one of the commonly performed procedures done under local anaesthesia, mostly on new-borns, infants and young children. The results of the technique have been evaluated in many studies throughout the world. We have done a large number of cases and present the results of our retrospective descriptive study.
导言:包皮环切术既是一种宗教习俗,也是一种外科手术,既有风险也有益处。包皮环切术有多种手术方法。选择哪种方法取决于执行手术的医务人员的技能和偏好。包皮环切术是在局部麻醉下进行的常用手术之一,主要针对新生儿、婴幼儿。世界各地的许多研究都对该技术的效果进行了评估。我们已经完成了大量病例,并展示了我们的回顾性描述性研究结果。
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引用次数: 0
Contrast Tuned Imaging for Detection of Left Ventricular apical thrombus: A Case Report 用于检测左心室心尖血栓的对比调谐成像:病例报告
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.01
Akhil Mehrotra, Mohammed Shaban, Shubham Kacker
Thrombi represent the most frequently found intracardiac masses. Left ventricular thrombus (LVT) is an important complication in patients with ischemic heart diseases and in those with dilated cardiomyopathy and systolic heart failure. The diagnosis of left ventricular thrombus remains important since anticoagulation will reduce the risk of systemic embolization and stroke. Despite advances in other imaging modalities, echocardiography remains the most important tool for diagnosis and risk stratification in patients predisposed to develop left ventricular thrombi. We are presenting a case report of 62 years old gentleman who had suffered from anterior wall myocardial infarction (AWMI) in the recent past, and now has developed LVT which was detected by contrast tuned imaging (CTI) technology based contrast echocardiography. This is a first case report of detection of LVT by this ingenious technology. Keywords: Thrombus, Left Ventricle, Ischemic Heart Disease, Anterior Wall Myocardial Infarction, Contrast Tuned Imaging, Left Ventricular Opacification.
血栓是最常见的心内肿块。左心室血栓是缺血性心脏病患者以及扩张型心肌病和收缩性心力衰竭患者的重要并发症。左心室血栓的诊断仍然非常重要,因为抗凝可以降低全身栓塞和中风的风险。尽管其他成像方式取得了进步,但超声心动图仍是诊断易患左心室血栓的患者并对其进行风险分层的最重要工具。我们在此报告一例 62 岁男性患者的病例,他在不久前曾患前壁心肌梗死(AWMI),现在通过基于对比调谐成像(CTI)技术的对比超声心动图检查发现了左心室血栓。这是首例利用这一独创技术检测出左心室室间隔缺损的病例报告。关键词血栓 左心室 缺血性心脏病 前壁心肌梗死 对比调强成像 左心室不透明
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引用次数: 0
Assessing the efficacy of medical vs surgical approaches for treating carpal tunnel syndrome: Systematic review 评估药物与手术治疗腕管综合征的疗效:系统回顾
Pub Date : 2023-10-30 DOI: 10.18535/jmscr/v11i10.08
Dr Ahmed Elhamalawy
Background: Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome that is caused by compression of the median nerve at the wrist joint causing variety of signs and symptoms. There are several measures to treat CTS including surgical and non-surgical approaches. Objectives: this systematic review aims to compare and evaluate the efficacy of conservative (non-surgical) and surgical approaches in treatment of CTS. Methods: Using predefined keywords related to this condition, an extensive search of medical databases, including PubMed and Cochrane library, was carried out to find and select randomized controlled clinical trials evaluating the effects of conservative treatment compared to surgical treatment released up to August 2023. The quality of the included research was rigorously evaluated, and data were extracted. After reviewing pertinent papers for relevance and quality, data was gathered for analysis. Key outcome measures included pain reduction and functional improvement
背景:腕管综合征(CTS)是最常见的周围神经卡压综合征,是由于正中神经在腕关节处受到压迫而引起的各种体征和症状。目前有多种治疗 CTS 的方法,包括手术和非手术疗法。目的:本系统综述旨在比较和评估保守(非手术)和手术方法治疗 CTS 的疗效。方法:使用与该病症相关的预定义关键词,对包括 PubMed 和 Cochrane 图书馆在内的医学数据库进行了广泛检索,寻找并筛选出截至 2023 年 8 月发布的评估保守治疗与手术治疗效果的随机对照临床试验。对纳入研究的质量进行了严格评估,并提取了数据。在对相关论文的相关性和质量进行审查后,收集数据进行分析。主要结果指标包括疼痛减轻和功能改善
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引用次数: 0
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Journal of Medical Science And clinical Research
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