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4 years institutional experience in the management of Trichobezoar: About 5 Cases 4 年管理三叶虫的机构经验:约 5 个病例
Pub Date : 2023-08-30 DOI: 10.18535/jmscr/v11i8.04
Nitin Jain
Background: Trichobezoar is an uncommon clinical entity in which ingested hair mass accumulates within the digestive tract. Trichobezoars are usually located in the stomach, but may extend through the pylorus into the duodenum and small bowel (Rapunzel syndrome). This entity is usually associated with trichotillomania and trichophagia or other psychiatric disorders. It is generally observed in children and young females with psychological disorders. Untreated cases may lead to grave complications. We present our experience with five patients and provide a review of the recent literature. Material and Methods: We retrospectively analysed the clinical data of five patients treated for trichobezoar in pediatric surgery department during 4-year-period between 2018 and 2022. Their medical charts were reviewed with respect to symptoms, diagnostic procedures including any Imaging (abdominal ultrasonography and abdominal computed tomography) or upper GI endoscopy and treatment.
背景:三叶虫是一种不常见的临床病症,患者摄入的毛发块会在消化道内积聚。三叶虫通常位于胃部,但也可能通过幽门进入十二指肠和小肠(长发公主综合征)。这种病症通常与毛手毛脚症、毛食癖或其他精神疾病有关。它通常发生在有心理障碍的儿童和年轻女性身上。未经治疗的病例可能会导致严重的并发症。我们将介绍五例患者的治疗经验,并对近期文献进行回顾。材料和方法:我们回顾性分析了 2018 年至 2022 年 4 年间在小儿外科接受治疗的 5 名三叶虫患者的临床数据。我们回顾了他们的病历,包括症状、诊断程序(包括任何影像学检查(腹部超声波检查和腹部计算机断层扫描)或上消化道内窥镜检查)和治疗。
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引用次数: 0
Left Ventricular Myocardial Deformation Assessment by 4Dimensional XStrain Speckle Tracking Echocardiography: An Innovative Technology 通过四维 X 应变斑点追踪超声心动图评估左心室心肌变形:一项创新技术
Pub Date : 2023-08-30 DOI: 10.18535/jmscr/v11i8.09
Akhil Mehrotra
Strain based imaging techniques, particularly speckle tracking echocardiography (STE) have been shown to have clinical utility in a variety of clinical settings. Currently, STE is being embraced and increasingly adopted in numerous echocardiographic laboratories worldwide. In context with contemporary non invasive cardiovascular procedures, 2Dimensional STE is most sought-after method to evaluate LV strain, rotation, twist and torsion. Two dimensional (2D), three dimensional (3D) and 4Dimensional (4D) deformation assessment by STE is inherently associated with certain limitations. For better appraisal of LV contractile properties recently introduced updated version of 4D XStrain STE has been employed to analyse the various complex multidimensional LV mechanics. This novel technology is a reliable, affordable and a simple tool for estimation of regional and global myocardial function. Furthermore, 4D XStrain STE can accurately quantify the 4D LV ejection-fraction, end-diastolic and end-systolic volumes and sphericity index (SI). However, this distinctive technology has not been widely adopted and its assessment is still limited to research applications. Hence we aimed to familiarize this innovative technology by comprehensively addressing its technique, advantages and limitations, with the intent that it may serve a more meaningful purpose in the current volatile scenario of cardio-vascular disease. Keywords: 4Dimensional XStrain Echocardiography, LV strain, LV rotation, LVtwist, LV untwist, LV torsion.
基于应变的成像技术,尤其是斑点追踪超声心动图(STE)已被证明在各种临床环境中具有临床实用性。目前,STE 已被全球众多超声心动图实验室所接受,并被越来越多地采用。在当代无创心血管手术中,二维 STE 是评估左心室应变、旋转、扭曲和扭转的最受欢迎的方法。用 STE 评估二维(2D)、三维(3D)和四维(4D)变形有其固有的局限性。为了更好地评估左心室收缩特性,最近推出的更新版 4D XStrain STE 被用来分析各种复杂的多维左心室力学。这项新技术是一种可靠、经济、简单的工具,可用于评估区域和整体心肌功能。此外,4D XStrain STE 还能准确量化 4D 左心室射血分数、舒张末期和收缩末期容积以及球形指数(SI)。然而,这项独特的技术尚未被广泛采用,其评估仍仅限于研究应用。因此,我们旨在通过全面探讨其技术、优势和局限性来熟悉这一创新技术,以期它能在当前心血管疾病的多变形势下发挥更有意义的作用。关键词四维 X 应变超声心动图 左心室应变 左心室旋转 左心室扭转 左心室解旋 左心室扭转
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引用次数: 0
Determination of Prostate Specific Antigen Level among Male Patients with Bacterial Urinary Tract Infections Attending Kuje General Hospital Abuja, Nigeria 尼日利亚阿布贾库杰总医院细菌性尿路感染男性患者前列腺特异抗原水平的测定
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.03
Ajang, A. Y., Ogaji
Recent hospital and cancer registry data shows increasing prostate cancer incidence in Nigeria, which was previously regarded as a low incidence region. Prostate cancer is the leading cause of cancer death among men in Nigeria and second most common cancers of men worldwide and sexual history has been a consistent risk factor. Prostate specific antigen (PSA) test is still the single most important test for early detection of prostate cancer worldwide. However, not much is reported about prostate cancer in relation to urinary tract infections in Africa. This study investigates the prevalence of prostate cancer risk in and bacterial urinary tract infections among men in Abuja, Nigeria. One Hundred (100) samples each of blood and urine were collected, from fifty (50) male patients suffering from urinary tract infections and fifty (50) apparently healthy males attending Kuje General Hospital Abuja, Nigeria. All the blood samples were subjected to PSA analysis using Enzyme-linked Immunosorbent Assay procedure (Diagnostic Automation/ Cortez Diagnostics, Inc, USA) while urine analysis (microscopy, culture and biochemical identification) was performed on the urine to isolate and identify the common bacteria associated with urinary tract infections among the study population.
最近的医院和癌症登记数据显示,尼日利亚的前列腺癌发病率在不断上升,而尼日利亚以前被认为是低发病率地区。前列腺癌是尼日利亚男性癌症死亡的主要原因,也是全球第二大男性常见癌症,性史一直是一个风险因素。前列腺特异性抗原(PSA)检测仍然是全球早期发现前列腺癌的最重要检测方法。然而,非洲有关前列腺癌与尿路感染关系的报道并不多。本研究调查了尼日利亚阿布贾男性患前列腺癌的风险和细菌性尿路感染的流行情况。研究人员从五十(50)名尿路感染男性患者和五十(50)名在尼日利亚阿布贾 Kuje 综合医院就诊的表面健康男性中各采集了一百(100)份血液和尿液样本。所有血样均采用酶联免疫吸附试验程序(美国诊断自动化公司/Cortez Diagnostics, Inc)进行 PSA 分析,同时对尿液进行分析(显微镜检查、培养和生化鉴定),以分离和鉴定研究人群中与尿路感染有关的常见细菌。
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引用次数: 0
Preservation of Vaginal Length by Vertical vs Horizontal Vault Closure Technique after Vaginal Hystrectomy 阴道子宫切除术后采用垂直与水平穹隆闭合技术保留阴道长度的比较
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.02
S. Jeelani
Objective: To compare vaginal length preservation between vertical and horizontal vault closure technique after vaginal hystrectomy. Methods: Randomized prospective Study was conducted at two private hospitals in Kashmir valley. 46 women who attended gynecology clinic between Jan 2016 to Jan 2021 with POPQ grade 1 prolapse were randomized into two groups according to vaginal vault closure technique (horizontal 23 vs vertical 23). Results: Vaginal length measured pre-operatively between horizontal and vertical group was similar with mean ±SD (7.6±0.82) and 7.79±0.80). Immediate postoperative vaginal length was significantly short in horizontal group as compared to vertical closure group with mean±SD (6.4±0.88) and 7.31±0.72). Mean difference in vaginal length between two groups before and after surgery was 1.2(0.12) centimeters (horizontal) and 0.4(0.11) centimeters vertical group. P<.001 Conclusion: vertical vaginal vault closure preserves vaginal length as compared to horizontal vault closure. Keywords: vault closure, vaginal hystrectomy, vaginal length, vertical, horizontal.
目的比较阴道子宫切除术后垂直和水平穹隆闭合技术对阴道长度的保留。方法: 在克什米尔山谷的两家私立医院进行了随机前瞻性研究:随机前瞻性研究在克什米尔山谷的两家私立医院进行。根据阴道穹窿闭合技术(水平 23 与垂直 23),将 46 名在 2016 年 1 月至 2021 年 1 月期间到妇科门诊就诊、患有 POPQ 1 级脱垂的女性随机分为两组。结果:水平组和垂直组术前测量的阴道长度相似,平均值(±SD)分别为(7.6±0.82)和(7.79±0.80)。术后即刻阴道长度水平组明显短于垂直闭合组(平均值±SD(6.4±0.88)和 7.31±0.72)。两组术前和术后阴道长度的平均差异为:水平组 1.2(0.12)厘米,垂直组 0.4(0.11)厘米。P<.001 结论:与水平穹隆闭合术相比,垂直穹隆闭合术可保留阴道长度。关键词:穹隆关闭术;阴道子宫切除术;阴道长度;垂直;水平。
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引用次数: 0
Prospective Study to Compare Outcomes Following Hypofractionated Radiotherapy versus Conventional Radiotherapy in Carcinoma Breast 比较乳腺癌超分割放疗与传统放疗疗效的前瞻性研究
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.04
Dr Vivek Kumar Pandey
Background: Breast cancer is now the most common cancer worldwide (GLOBOCAN, 2020). It is the most common cancer among women in developed countries. The age standardized incidence rate of breast cancer in India is 25.8% per 100,000 women (GLOBOCAN, 2020). By 2020, breast cancer overtook cervical cancer as the most common type of cancer among all women in India. Breast irradiation has been shown to reduce the risk of local recurrence after breast-conserving surgery from about 30% to <10% at 10 years. Aims & Objectives: Randomize Breast carcinoma into two arms - Arm A :- 39GY in 13 fractions over 2.3 weeks & Arm B:- 50 GY in 25 fractions over 5weeks. Compare locoregional response in two arms 4 weeks after completion of radiation therapy and at the end of six months of follow up. Compare acute and chronic toxicities in the two arms.
背景:乳腺癌是目前全球最常见的癌症(GLOBOCAN,2020 年)。它是发达国家妇女中最常见的癌症。在印度,乳腺癌的年龄标准化发病率为每 10 万名妇女 25.8%(GLOBOCAN,2020 年)。到 2020 年,乳腺癌将超过宫颈癌,成为印度妇女最常见的癌症类型。事实证明,乳房照射可将保乳手术后局部复发的风险从 30% 左右降至 10 年后的 <10%。目的与目标:将乳腺癌患者随机分为两组--A组:39GY,13次,2.3周;B组:50GY,25次,5周。比较两组患者在放疗结束 4 周后和 6 个月随访结束时的局部反应。比较两组患者的急性和慢性毒性反应。
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引用次数: 0
To Study Hematological Features in Various Etiologies of Macrocytic Anemias 研究巨幼红细胞性贫血各种病因的血液学特征
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.05
Mamatha G
Background: Mean corpuscular volume (MCV) increases by more than 100 fl. in macrocytosis, a condition in which erythrocytes are larger than normal. The purpose of this study was to evaluate the haematological characteristics in various aetiologies and to determine the underlying reasons of macrocytosis, which was found in regular hemograms. In addition to doing full blood counts, renal function tests, liver function tests, vitamin B12 assays, folate assays, and peripheral smear evaluations and few case were bone marrow examination. Material and Methods: In this prospective observational study conducted over a period of one-year, medical records of 250 subjects were evaluated. Data was compiled of Megaloblastic, Non-megaloblastic Macrocytosis levels, along with clinical diagnosis and other biochemical parameters. Based on clinical evaluation and hematological and biochemeical evidence, patients were diagnosed as positive cases of Megaloblastic(166), Non-Megaloblastic (133).Among this two variable group Mean ±SD were also calculated .
背景:大红细胞症是一种红细胞大于正常值的病症,大红细胞症患者的平均血球容积(MCV)会增加 100 多毫升。本研究的目的是评估各种病因的血液学特征,并确定在常规血象图中发现的大红细胞症的根本原因。除了进行全血细胞计数、肾功能检测、肝功能检测、维生素 B12 检测、叶酸检测和外周涂片评估外,少数病例还进行了骨髓检查。材料和方法:在这项为期一年的前瞻性观察研究中,对 250 名受试者的病历进行了评估。研究人员收集了巨幼红细胞症、非巨幼红细胞症患者的数据,以及临床诊断和其他生化指标。根据临床评估、血液学和生物化学证据,患者被诊断为巨幼红细胞症阳性病例(166 例)和非巨幼红细胞症阳性病例(133 例)。
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引用次数: 0
Double Outlet Right Ventricle with Pulmonary Atresia and Antero-Posterior Malposition of Great Arteries: Transthoracic Echocardiographic Evaluation of a rare cyanotic congenital heart disorder 双出口右心室伴肺动脉闭锁和大动脉前后错位:对一种罕见紫绀型先天性心脏病的经胸超声心动图评估
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.08
Akhil Mehrotra
Double outlet right ventricle (DORV) is a heterogeneous group of abnormal ventriculoarterial connections where, by definition, both great arteries (pulmonary artery and aorta) arise primarily from the morphologically right ventricle, This condition affects 1-1.5% of the patients with congenital heart diseases, with a frequency of 1 in each 10,000 live births. We are reporting a case of seven year old deeply cyanotic child with DORV, subaortic VSD with rare anatomic features of antero-posterior malposition of great arteries (GA) and pulmonary vavular atresia, with conspicuous absence of patent ductusarteriosus (PDA) or major aorto-pulmonary collaterals (MAPCAs), despite the presence of atretic pulmonary valve. Keywords: DORV, Pulmonary atresia, TGA, VSD, subaortic VSD, overriding of Aorta, cyanotic congenital heart defects.
双出口右心室(DORV)是一类异常的心室-动脉连接,顾名思义,双侧大动脉(肺动脉和主动脉)主要来自形态上的右心室。这种情况影响 1-1.5% 的先天性心脏病患者,发生率为每 10,000 例活产中就有 1 例。我们报告了一例七岁的深紫绀患儿,他患有 DORV、主动脉瓣下 VSD,并伴有罕见的大动脉前后位置不正(GA)和肺动脉瓣闭锁的解剖学特征,尽管存在闭锁的肺动脉瓣,但没有明显的动脉导管未闭(PDA)或大动脉-肺动脉袢(MAPCAs)。关键词DORV、肺动脉闭锁、TGA、VSD、主动脉瓣下VSD、主动脉覆膜、紫绀型先天性心脏缺陷。
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引用次数: 0
Retrospective study of Mortality analysis in different Waves during COVID-19 in tertiary care centre of Delhi 德里三级医疗中心 COVID-19 期间不同波段死亡率分析的回顾性研究
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.06
Dr Ankush Bansal
COVID 19 is a communicable disease which has spread all over the world due to human-to-human transmission. The initial symptoms are non specific, and it presents with fever and cough, which can then resolve spontaneously or progress to acute respiratory distress syndrome (ARDS), multiple organ failure, and death. This is a retrospective study conducted in a tertiary care center in Delhi to find out association of factors like age, gender and various co morbidities on COVID-19 mortality. Male patients with older age and having co morbidities were found to have higher mortality and results were statistically significant.
COVID 19 是一种传染性疾病,通过人际传播在世界各地蔓延。初期症状无特异性,表现为发热和咳嗽,随后可自行缓解或发展为急性呼吸窘迫综合征(ARDS)、多器官功能衰竭和死亡。这是一项在德里一家三级护理中心进行的回顾性研究,旨在找出年龄、性别和各种并发症等因素与 COVID-19 死亡率的关系。研究发现,年龄较大且合并多种疾病的男性患者死亡率较高,且结果具有统计学意义。
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引用次数: 0
A Comparative Study of Serum Calcium and Magnesium in Post-Menopausal and Pre- Menopausal Women 绝经后和绝经前妇女血清钙和镁的比较研究
Pub Date : 2023-07-30 DOI: 10.18535/jmscr/v11i7.09
Dr Lanke Vani
Background: Menopause is marked by decreased female sex hormones and many of the symptoms experienced during this phase may be related to changes in serum levels of certain trace minerals especially calcium and magnesium. Aim: The main purpose of the study was to measure serum calcium and magnesium in postmenopausal women and to compare with that in pre-menopausal women. Methods: Serum calcium and magnesium were estimated in 30 postmenopausal women and 30 premenopausal women, who were selected following inclusion and exclusion criteria. Statistical analysis was done by using Graph pad Quickcalcs calculator. Student's unpaired t test was done to compare between both groups and p-value was determined to know the statistical significance. Results: Postmenopausal women were found to have lower serum calcium (8.659±0.91) and serum magnesium (1.63±0.16) when compared to premenopausal women who had serum calcium of (9.604 ± 0.70) and serum magnesium (2.48±0.55). The lowered calcium and magnesium levels were found to be extremely statistically significant with a p-value of <0.0001. Conclusion: Serum calcium and magnesium were decreased in post-menopausal women when compared to pre-menopausal women, which needs to be corrected to avoid certain postmenopausal symptoms and other serious health problems. This may improve cardiovascular and bone health in post menopausal women.
背景:绝经的特点是女性性激素减少,在这一阶段出现的许多症状可能与血清中某些微量元素(尤其是钙和镁)水平的变化有关。目的:本研究的主要目的是测量绝经后妇女的血清钙和镁含量,并与绝经前妇女的血清钙和镁含量进行比较。方法:测量绝经后妇女的血清钙和镁:按照纳入和排除标准,对 30 名绝经后妇女和 30 名绝经前妇女的血清钙和镁进行了估计。使用 Graph pad Quickcalcs 计算器进行统计分析。采用学生非配对 t 检验对两组进行比较,并确定 p 值以了解统计意义。结果与绝经前妇女的血清钙(9.604 ± 0.70)和血清镁(2.48±0.55)相比,绝经后妇女的血清钙(8.659±0.91)和血清镁(1.63±0.16)更低。研究发现,钙和镁水平的降低具有极其显著的统计学意义,P 值小于 0.0001。结论与绝经前相比,绝经后妇女的血清钙和镁含量有所下降,这需要加以纠正,以避免出现某些绝经后症状和其他严重的健康问题。这可能会改善绝经后妇女的心血管和骨骼健康。
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引用次数: 0
Building Nurse Competence to Address Global Health and Global Era Challenges 培养护士应对全球健康和全球时代挑战的能力
Pub Date : 2023-06-30 DOI: 10.18535/jmscr/v11i6.18
Widjijati Herry Prasetyo
Introduction: Globalization is a fact of life. In addition to having an impact on the economic, social, political, technological, environmental, and cultural spheres of human life, globalization also affects the health care and educational systems. Health-related educational institutions, particularly nursing programs, must be able to turn out graduates who can compete in the modern world. Methods: Studies are systematically found utilizing electronic databases that have been Scopus indexed, such as ProQuest, Science Direct, CINALH, and PubMed. The Medical Subject Heading (MeSH) search terms for the papers in this investigation are globalization AND global health AND nursing. Four articles that fulfill the requirements were left after articles were found using an electronic database search and then chosen based on the inclusion and exclusion criteria. Results: This review study discovered that in order for nursing students to successfully navigate the issues of globalization and global health, they must increase their global health nursing competences. Conclusions: The best available data is compiled in this study to help universities and other interested parties create and assess global health nursing competency-strengthening programs for nursing students. Keywords: globalization; global health; nursing
导言全球化是一个不争的事实。除了对人类生活的经济、社会、政治、技术、环境和文化领域产生影响外,全球化还影响到医疗保健和教育系统。与健康相关的教育机构,尤其是护理专业,必须能够培养出能够在现代世界中竞争的毕业生。研究方法:利用已被 Scopus 索引的电子数据库,如 ProQuest、Science Direct、CINALH 和 PubMed,系统地查找相关研究。本调查论文的医学主题词(MeSH)检索词为全球化、全球健康和护理。在使用电子数据库搜索到符合要求的文章后,根据纳入和排除标准选择了四篇符合要求的文章。研究结果本综述研究发现,为了让护理专业学生成功应对全球化和全球健康问题,他们必须提高全球健康护理能力。结论:本研究汇编了现有的最佳数据,以帮助大学和其他相关方为护理专业学生创建和评估全球健康护理能力强化项目。关键词:全球化;全球健康;护理
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引用次数: 0
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Journal of Medical Science And clinical Research
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