Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.562
Q. Lê, Hoang Minh Duc, Thi Tam Quyen Doan, T. Chu, Thu Thao Dao, Thi Thanh Huong Ha
Using information technology and traditional oriental medicine research, we have screened 5 Vietnamese herbs that contain active ingredients with antiviral effects. Andrographispaniculata, Syzygiumaromaum, Zingiber officinale Rose, Houttuyniacordata, Glycyrrhizauralensis Fisch. The active ingredients in herbs are extracted by ultrasound in a water-ethanol solvent system and made in the form of a nanometer complex, then mixed in specified proportions to form the product. The product was evaluated cytotoxicity by MTT (3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay and evaluated the growth inhibition effect of H5N1 virus. Result: The complex of active ingredients in the composition has the nanometer size, the main size is 443 nm, the zeta potential is -11.9 mV. The inhibitory activity of the H5N1 virus was dose-dependent, and a concentration of 3 mg/mL completely inhibited the growth of the H5N1 virus in the erythrocyte agglutination test.
{"title":"Study on screening Vietnamese herbs with antiviral activity to create products to support treatment of some diseases caused by RNA-virus","authors":"Q. Lê, Hoang Minh Duc, Thi Tam Quyen Doan, T. Chu, Thu Thao Dao, Thi Thanh Huong Ha","doi":"10.35248/2157-7439.21.12.562","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.562","url":null,"abstract":"Using information technology and traditional oriental medicine research, we have screened 5 Vietnamese herbs that contain active ingredients with antiviral effects. Andrographispaniculata, Syzygiumaromaum, Zingiber officinale Rose, Houttuyniacordata, Glycyrrhizauralensis Fisch. The active ingredients in herbs are extracted by ultrasound in a water-ethanol solvent system and made in the form of a nanometer complex, then mixed in specified proportions to form the product. The product was evaluated cytotoxicity by MTT (3-(4,5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay and evaluated the growth inhibition effect of H5N1 virus. Result: The complex of active ingredients in the composition has the nanometer size, the main size is 443 nm, the zeta potential is -11.9 mV. The inhibitory activity of the H5N1 virus was dose-dependent, and a concentration of 3 mg/mL completely inhibited the growth of the H5N1 virus in the erythrocyte agglutination test.","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"60 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79228366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.E113
Amedeo Xu
{"title":"Note on Technology of Nanosensor","authors":"Amedeo Xu","doi":"10.35248/2157-7439.21.12.E113","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.E113","url":null,"abstract":"","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"88 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76050357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.E114
Amedeo Xu
{"title":"Note on Nanocomposites in Engineering Applications","authors":"Amedeo Xu","doi":"10.35248/2157-7439.21.12.E114","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.E114","url":null,"abstract":"","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"27 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84598235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.559
Gizaw Mekonnen
Nanotechnology is research and technology development at the atomic, molecular and macromolecular levels at the scale of approximately 1 - 100 nanometer range, to provide a fundamental understanding of phenomena and materials at the Nano scale and to create and use structures, devices and systems that have novel properties and functions because of their small and/or intermediate size. Nanotechnology has the potential to solve many more puzzles related to animal health, products and breeding. The applications of nanotechnology become the proving ground for untried and more controversial techniques from Nano capsule vaccines to sex selection in breeding. There are numerous applications of nanotechnology in veterinary medicine including disease diagnosis, treatment, drug delivery, animal breedingand improving and boosting animal origin food product. It provide variety of new nanomaterial and nanoparticle including Nano chips, nanosenser, liopsoms, quantum dot, gold nanoparticle, magnetic nanoparticle etc for vaccination, pathogen detection, disease diagnosis, animal breeding and provide polymeric nanoparticle, carbon nanotube, Nano shell dendrites, etc for delivering antimicrobial nanoparticle and Nano medicine for treatment of disease. It is swiftly changing the diagnosis and treatment patterns at faster and low cost in less time duration.
{"title":"Review on Application of Nanotechnology in Animal Health and Production","authors":"Gizaw Mekonnen","doi":"10.35248/2157-7439.21.12.559","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.559","url":null,"abstract":"Nanotechnology is research and technology development at the atomic, molecular and macromolecular levels at the scale of approximately 1 - 100 nanometer range, to provide a fundamental understanding of phenomena and materials at the Nano scale and to create and use structures, devices and systems that have novel properties and functions because of their small and/or intermediate size. Nanotechnology has the potential to solve many more puzzles related to animal health, products and breeding. The applications of nanotechnology become the proving ground for untried and more controversial techniques from Nano capsule vaccines to sex selection in breeding. There are numerous applications of nanotechnology in veterinary medicine including disease diagnosis, treatment, drug delivery, animal breedingand improving and boosting animal origin food product. It provide variety of new nanomaterial and nanoparticle including Nano chips, nanosenser, liopsoms, quantum dot, gold nanoparticle, magnetic nanoparticle etc for vaccination, pathogen detection, disease diagnosis, animal breeding and provide polymeric nanoparticle, carbon nanotube, Nano shell dendrites, etc for delivering antimicrobial nanoparticle and Nano medicine for treatment of disease. It is swiftly changing the diagnosis and treatment patterns at faster and low cost in less time duration.","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"75 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77231479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.567
E. Podkorytov, M. Šťastný, M. Chvojkova, L. Cejkova, O. H. Asnaz, J. Benedikt, M. Muller, P. Galář, K. Valeš, K. Herynková
Diseases affecting the central nervous system (CNS) are considered to be some of the most debilitating conditions worldwide. The range of standard therapies for disorders affecting CNS is largely limited for many patients. Nonetheless, nanoparticle-based drug delivery offers itself to be a promising strategy for effective drug delivery into the brain, addressing the frequently arising complications with blood-brain barrier crossing. This study compared the drug adsorption ability and the surface chemistry of two types of silicon nanoparticles (Si-NPs). Si- NPs were prepared using two methods: electrochemical etching of Si wafers (Si-E) and low-pressure plasma synthesis (Si-P). Silicon nanoparticles were characterized by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and nitrogen physisorption (method of Barrett, Joyner, and Halenda (BJH) and method of Brunauer, Emmett and Teller (BET)). The size and morphology were characterized by high-resolution transmission electron microscopy (HRTEM) linked with energy-dispersive X-ray spectroscopy (EDAX) and dynamic light scattering (DLS), respectively. The concentration of the drug substance that was captured by the silicon-based drug delivery system was determined by ultra high-performance liquid-chromatography-diode-array (UHPLC-DAD) method. Results of XPS showed that the Si-E are more oxidized than Si-P. The BET analysis showed us that the Si-E have more surface area, pore volume and grain size then the Si-P, and Si-P have a bigger pore size than Si-E. We also demonstrated by XRD that silicon nanoparticles prepared by both methods have a crystalline structure. The Si-P adsorption analysis of the model compound (ferulic acid) showed better adsorption ability than Si-E. The size of the Si-P (40- 120 nm) was also measured by HRTEM.
影响中枢神经系统(CNS)的疾病被认为是世界上最使人衰弱的疾病之一。对于许多患者来说，影响中枢神经系统疾病的标准治疗范围在很大程度上是有限的。尽管如此，基于纳米颗粒的药物递送为有效的药物递送到大脑提供了一种有前途的策略，解决了频繁出现的血脑屏障穿越并发症。本研究比较了两种硅纳米颗粒(Si-NPs)的药物吸附能力和表面化学性质。采用硅晶片电化学刻蚀(Si- e)和低压等离子体合成(Si- p)两种方法制备了Si- NPs。采用x射线光电子能谱(XPS)、x射线衍射(XRD)和氮物理吸附(Barrett, Joyner, and Halenda法(BJH)和Brunauer, Emmett and Teller法(BET))对硅纳米颗粒进行了表征。利用高分辨率透射电子显微镜(HRTEM)、能量色散x射线能谱(EDAX)和动态光散射(DLS)分别对其尺寸和形态进行了表征。采用超高效液相色谱-二极管阵列(UHPLC-DAD)法测定硅基给药系统捕获的原料药的浓度。XPS结果表明Si-E比Si-P更容易被氧化。BET分析表明，Si-E比Si-P具有更大的比表面积、孔隙体积和晶粒尺寸，Si-P比Si-E具有更大的孔径。通过XRD分析表明，两种方法制备的纳米硅均具有晶体结构。模型化合物(阿魏酸)的Si-P吸附性能优于Si-E。用HRTEM测定了Si-P的尺寸(40 ~ 120 nm)。
{"title":"Comparison of Si Nanoparticle types for use as a Potencial Drug Delivery System for Central Nervous System Diseases","authors":"E. Podkorytov, M. Šťastný, M. Chvojkova, L. Cejkova, O. H. Asnaz, J. Benedikt, M. Muller, P. Galář, K. Valeš, K. Herynková","doi":"10.35248/2157-7439.21.12.567","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.567","url":null,"abstract":"Diseases affecting the central nervous system (CNS) are considered to be some of the most debilitating conditions worldwide. The range of standard therapies for disorders affecting CNS is largely limited for many patients. Nonetheless, nanoparticle-based drug delivery offers itself to be a promising strategy for effective drug delivery into the brain, addressing the frequently arising complications with blood-brain barrier crossing. This study compared the drug adsorption ability and the surface chemistry of two types of silicon nanoparticles (Si-NPs). Si- NPs were prepared using two methods: electrochemical etching of Si wafers (Si-E) and low-pressure plasma synthesis (Si-P). Silicon nanoparticles were characterized by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and nitrogen physisorption (method of Barrett, Joyner, and Halenda (BJH) and method of Brunauer, Emmett and Teller (BET)). The size and morphology were characterized by high-resolution transmission electron microscopy (HRTEM) linked with energy-dispersive X-ray spectroscopy (EDAX) and dynamic light scattering (DLS), respectively. The concentration of the drug substance that was captured by the silicon-based drug delivery system was determined by ultra high-performance liquid-chromatography-diode-array (UHPLC-DAD) method. Results of XPS showed that the Si-E are more oxidized than Si-P. The BET analysis showed us that the Si-E have more surface area, pore volume and grain size then the Si-P, and Si-P have a bigger pore size than Si-E. We also demonstrated by XRD that silicon nanoparticles prepared by both methods have a crystalline structure. The Si-P adsorption analysis of the model compound (ferulic acid) showed better adsorption ability than Si-E. The size of the Si-P (40- 120 nm) was also measured by HRTEM.","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"30 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91038729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.35248/2157-7439.21.12.573
Suruti Gupta, R. Shukla
This paper reviews the expected wide and profound impact of nanotechnology for future wireless devices and communication technologies. This article points out the possibilities of overcoming the same problem set from a device perspective by taking advantage of the merits of nanotechnologies. At the same time, open research issues and challenges are identified to spark new interests and developments in this field. Devices that use wireless communication range from RFID tags to TV receivers, and satellites to mobile phones. The availability of internet access from tablets and mobile phones is growing at an exponential rate, causing increasing demands on the performance of wireless networks and mobile devices. Some passive components necessary in wireless devices, such as inductors and capacitors, cannot be minimized as quickly as transistors and integrated circuits. This imbalance makes it likely that the performance requirements of mobile handsets will exceed the capabilities of current RF technologies within the next 10 to 15 years. As well as the global growth in mobile internet access via tablets and smartphones, wireless sensors, health monitoring systems and other devices dependent on wireless communication are becoming more and more prevalent. Developing more compact, more efficient, and less expensive wireless communication devices will have significant impact on these areas and enable new solutions for healthcare services, logistics and environmental monitoring. The devices that use wireless communication ranges from RFID tags to television set receivers and satellites to mobile phones. The availability of internet access from mobile devices is growing at an exponential rate that causes rising demand on the wireless network and mobile devices' performance. As the type of activities that consumers are engaging in over the wireless connections is changing day in day out, it has been an increased need for the devices to change also. For instance in radios, the increasing quantity of mobile internet traffic there has been increased the need for additional frequency for support. The modern world is becoming an intelligent interactive environment that has needs novel autonomous sensors with wireless communication links that require to be incorporated into an everyday object. This is the reason why sensors that are nanoenabled integrated with small RF transceivers are useful in monitoring air quality, water pollution among other aspects. The main drivers of changing into nanotechnology in wireless devices are needed for high performance, reduced consumption of power as well as reduced compact size.
{"title":"Applications of Nanotechnology for Wireless Sensor Networks","authors":"Suruti Gupta, R. Shukla","doi":"10.35248/2157-7439.21.12.573","DOIUrl":"https://doi.org/10.35248/2157-7439.21.12.573","url":null,"abstract":"This paper reviews the expected wide and profound impact of nanotechnology for future wireless devices and communication technologies. This article points out the possibilities of overcoming the same problem set from a device perspective by taking advantage of the merits of nanotechnologies. At the same time, open research issues and challenges are identified to spark new interests and developments in this field. Devices that use wireless communication range from RFID tags to TV receivers, and satellites to mobile phones. The availability of internet access from tablets and mobile phones is growing at an exponential rate, causing increasing demands on the performance of wireless networks and mobile devices. Some passive components necessary in wireless devices, such as inductors and capacitors, cannot be minimized as quickly as transistors and integrated circuits. This imbalance makes it likely that the performance requirements of mobile handsets will exceed the capabilities of current RF technologies within the next 10 to 15 years. As well as the global growth in mobile internet access via tablets and smartphones, wireless sensors, health monitoring systems and other devices dependent on wireless communication are becoming more and more prevalent. Developing more compact, more efficient, and less expensive wireless communication devices will have significant impact on these areas and enable new solutions for healthcare services, logistics and environmental monitoring. The devices that use wireless communication ranges from RFID tags to television set receivers and satellites to mobile phones. The availability of internet access from mobile devices is growing at an exponential rate that causes rising demand on the wireless network and mobile devices' performance. As the type of activities that consumers are engaging in over the wireless connections is changing day in day out, it has been an increased need for the devices to change also. For instance in radios, the increasing quantity of mobile internet traffic there has been increased the need for additional frequency for support. The modern world is becoming an intelligent interactive environment that has needs novel autonomous sensors with wireless communication links that require to be incorporated into an everyday object. This is the reason why sensors that are nanoenabled integrated with small RF transceivers are useful in monitoring air quality, water pollution among other aspects. The main drivers of changing into nanotechnology in wireless devices are needed for high performance, reduced consumption of power as well as reduced compact size.","PeriodicalId":16532,"journal":{"name":"Journal of Nanomedicine & Nanotechnology","volume":"79 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86200179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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