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Abstracts of randomized controlled trials in splint therapy for temporomandibular disorders: Reporting quality and spin 颞下颌关节紊乱夹板疗法随机对照试验摘要:报告质量和旋转。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-08-02 DOI: 10.1111/joor.13824
Liandi Cheng, Yunhao Zheng, Yaxin Weng, Yating Yi, Xueman Zhou, Nan Jiang, Xin Xiong

Background

Poor reporting quality and spin in randomized controlled trial (RCT) abstracts can lead to misinterpretation and distorted interpretation of results.

Objectives

This methodological study aimed to assess the reporting quality and spin among RCT abstracts on splint therapy for temporomandibular disorders (TMD) and explore the association between spin and potentially related factors.

Methods

The authors searched PubMed for RCTs on splint therapy for TMD. The reporting quality of each abstract was assessed using the original 16-item CONSORT for abstracts checklist. The authors evaluated the presence and characteristics of spin only in abstracts with nonsignificant primary outcomes according to pre-determined spin strategies. Logistic regression analyses were performed to identify factors associated with the presence of spin.

Results

A total of 148 abstracts were included in the reporting quality evaluation. The mean overall CONSORT score (OCS) was 5.86 (score range: 0–16). Only interventions, objectives and conclusions were adequately reported. Of the 61 RCT abstracts included for spin analysis, spin was identified in 38 abstracts (62.3%), among which 32 abstracts (52.3%) had spin in the Results section and 21 (34.4%) had spin in the Conclusions section. A significantly lower presence of spin was found in studies with exact p-value reporting (OR: 0.170; 95% CI: 0.032–0.887; p = .036) and a two-arm comparison design (OR: 11.777; 95% CI: 2.171–63.877; p = .004).

Conclusions

The reporting quality of RCT abstracts on splint therapy for TMD is suboptimal and the prevalence of spin is high. More awareness and joint efforts are needed to improve reporting quality and minimize spin.

背景:随机对照试验(RCT)摘要的报告质量不高和自旋会导致对结果的误读和曲解:本方法学研究旨在评估有关颞下颌关节紊乱(TMD)夹板疗法的 RCT 摘要的报告质量和自旋性,并探讨自旋性与潜在相关因素之间的关联:作者在 PubMed 上检索了有关 TMD 夹板疗法的 RCT。使用原始的 16 项 CONSORT 摘要核对表评估了每篇摘要的报告质量。作者根据预先确定的自旋策略,仅对主要结果不显著的摘要中是否存在自旋以及自旋的特征进行了评估。作者进行了逻辑回归分析,以确定与是否存在自旋相关的因素:共有 148 篇摘要纳入了报告质量评估。平均 CONSORT 总分 (OCS) 为 5.86(得分范围:0-16)。只有干预措施、目标和结论得到了充分报告。在纳入进行自旋分析的 61 篇 RCT 摘要中,有 38 篇摘要(62.3%)发现了自旋,其中 32 篇摘要(52.3%)在结果部分有自旋,21 篇摘要(34.4%)在结论部分有自旋。在报告精确P值(OR:0.170;95% CI:0.032-0.887;p = .036)和两臂对比设计(OR:11.777;95% CI:2.171-63.877;p = .004)的研究中,自旋现象明显较少:结论:有关夹板疗法治疗 TMD 的 RCT 摘要的报告质量不尽如人意,旋转的发生率很高。需要提高认识,共同努力,提高报告质量,尽量减少自旋。
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引用次数: 0
Effect of home-based tongue-strengthening exercise using a portable tool on oropharyngeal muscles in older adults with sarcopenic dysphagia: A randomised controlled study 一项随机对照研究:使用便携式工具在家中对患有肌肉萎缩性吞咽困难的老年人的口咽肌肉进行舌头强化训练的效果。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-29 DOI: 10.1111/joor.13818
Tae-Hyung Yoon, Motoyoshi Morishita, Na-Mi Han, Ji-Su Park

Background

Tongue-strengthening exercises may be used at home to strengthen swallowing-related oropharyngeal muscles in community-dwelling older adults with sarcopenic dysphagia; however, evidence of their effectiveness remains unclear.

Objective

This study aimed to investigate the effects of a home-based tongue-strengthening exercise (hTSE) using portable tool on swallowing-related oropharyngeal muscles in community-dwelling older adults with sarcopenic dysphagia.

Methods

Forth community-dwelling older adults with sarcopenic dysphagia were enrolled in the study. The participants were randomly assigned to the experimental and control groups. 1-Repetition Maximum (1-RM) of tongue muscle was measured in the experimental group using the Iowa Oral Performance Instrument, and hTSE was performed using a portable tool with an intensity corresponding to approximately 70%–80% of the range based on the 1-RM value (90 times/day, 5 days/week, for 8 weeks). The control group did not perform any tongue exercises. The primary outcome measures were tongue strength and thickness. The secondary outcome measure was suprahyoid muscle strength (digastric and mylohyoid muscles).

Results

The experimental group showed significantly greater increases in suprahyoid muscle (mylohyoid and digastric) thickness (p = .01 and .011, d = 1.0 and .55), as well as tongue strength and thickness (p < .001 and .029, d = 2.2 and .6) than the control group.

Conclusion

This study confirmed that hTSE using a portable tool is effective in increasing swallowing-related oropharyngeal muscle activity in older adults with sarcopenic dysphagia. Therefore, hTSE is recommended as an inexpensive, safe, and easy-to-use therapy for sarcopenic dysphagia in older adults.

背景:对于患有肌肉疏松性吞咽困难的社区居住老年人,可在家中进行舌部强化训练,以增强与吞咽相关的口咽肌肉;然而,其有效性的证据仍不明确:本研究旨在探讨使用便携式工具在家中进行舌部强化训练(hTSE)对患有肌肉疏松性吞咽困难的社区老年人吞咽相关口咽肌肉的影响:研究对象为患有肌肉疏松性吞咽困难的社区老年人。参与者被随机分配到实验组和对照组。实验组使用爱荷华州口腔能力测试仪测量舌肌的1-重复最大值(1-RM),并使用便携式工具进行hTSE训练,训练强度约为1-RM值范围的70%-80%(90次/天,5天/周,持续8周)。对照组不进行任何舌头练习。主要结果指标为舌头的力量和厚度。次要结果指标是舌上肌力(舌骨肌和舌骨肌):结果:实验组的舌上肌(肌舌肌和掘舌肌)厚度明显增加(p = .01 和 .011, d = 1.0 和 .55),舌的力量和厚度也明显增加(p 结论:实验组的舌上肌(肌舌肌和掘舌肌)厚度明显增加(p = .01 和 .011, d = 1.0 和 .55):本研究证实,使用便携式工具进行 hTSE 可以有效提高患有肌肉疏松性吞咽困难的老年人吞咽相关口咽肌肉的活动能力。因此,建议将 hTSE 作为治疗老年人肌肉疏松性吞咽困难的一种廉价、安全且易于使用的疗法。
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引用次数: 0
Pilot study on the relationship between oral function or subjective symptoms and appetite 关于口腔功能或主观症状与食欲之间关系的试点研究。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-26 DOI: 10.1111/joor.13811
Ryosuke Yamaga, Masato Chikaishi, Toshihiro Iwasaki, Akira Tada, Saki Mizutani, Kota Amano, Yoko Iwase, Hiroshige Taniguchi

Objective

This pilot study evaluated the relationships between appetite and oral function, and between appetite and the subjective symptoms of decreased oral function.

Methods

Seventy-one adult dental clinic patients (22 males, 66.0 ± 14.0 years) participated in this study. A Council on Nutrition Appetite Questionnaire score of ≤28 indicated anorexia, and the Mini Nutritional Assessment Short-form, body mass index and skeletal muscle mass index were used to define subject characteristics. Seven oral function tests and seven subjective symptoms related to oral function were evaluated. The relationship between subject characteristics, oral function tests, subjective symptoms and anorexia was analysed using the chi-square test and univariate and multivariate logistic regression.

Result

There were significant differences between the normal appetite group and the anorexia group for the 10-item Eating Assessment Tool (EAT-10) survey and the question ‘Food remains in the oral cavity after eating’ (p < .05). Univariate logistic regression found significant differences in the items of masticatory function, the EAT-10 survey and the question ‘Food remains in the oral cavity after eating’. Multivariate logistic regression revealed significant differences in masticatory function (AOR 4.35; 95% CI: 1.03–18.35; p = .045) and EAT-10 (AOR 6.27; 95% CI: 1.40–24.02; p = .016).

Conclusion

This pilot study investigated the influence of factors related to oral function on appetite. Relationships were found among poor masticatory function, poor swallowing function and anorexia.

目的: 本试验性研究评估了食欲与口腔功能之间的关系,以及食欲与口腔功能下降的主观症状之间的关系:这项试验性研究评估了食欲与口腔功能之间的关系,以及食欲与口腔功能下降的主观症状之间的关系:71名成年牙科诊所患者(22名男性,66.0 ± 14.0岁)参加了此次研究。营养委员会食欲问卷得分≤28分表示厌食,迷你营养评估简表、体重指数和骨骼肌质量指数用于确定受试者特征。对七项口腔功能测试和七项与口腔功能相关的主观症状进行了评估。采用卡方检验、单变量和多变量逻辑回归分析了受试者特征、口腔功能测试、主观症状和厌食之间的关系:结果:正常食欲组与厌食症组在 10 项进食评估工具(EAT-10)调查和 "进食后食物残留在口腔中 "问题上存在明显差异(p 结论:这项试验性研究调查了食欲正常组与厌食症组之间的影响因素:这项试点研究调查了与口腔功能有关的因素对食欲的影响。研究发现,咀嚼功能差、吞咽功能差与厌食之间存在关系。
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引用次数: 0
Non-coding RNA alterations in occlusal disharmony-induced anxiety-like behaviour 非编码 RNA 在咬合不协调诱发焦虑样行为中的改变
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-25 DOI: 10.1111/joor.13816
Mi Zhang, Ling Wu, Sihui Zhang, Yuxuan Li, Jiang Chen

Background

Occlusal disharmony (OD) may induce anxiety-like behaviours; however, the underlying mechanism remains unclear. Herein, we explored the expression profiles of non-coding RNAs (ncRNAs), along with their biological function and regulatory network, in anxiety-like behaviour induced by OD.

Materials and Methods

Occlusal disharmony was produced by anterior crossbite of C57BL/6 mice. Behavioural tests, corticosterone (CORT) and serotonin (5-HT) levels were used to measure anxiety. In addition, RNA sequencing was used to screen all differentially expressed (DE) ncRNAs. Moreover, the RNA-binding proteins interacting with ncRNAs were predicted by the ENCORI database and confirmed using western blots.

Results

The significant differences in behavioural tests and CORT suggested the successful induction of anxiety-like behaviour by OD. In OD mice, ncRNAs were significantly dysregulated. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses suggested that the DE ncRNAs were enriched in anxiety-related pathways. CircRNA10039 was upregulated, and PTBP1 was predicted to interact with circRNA10039. In addition, KEGG pathway analysis showed that PTBP1 may be associated with messenger RNA biogenesis and spliceosomes.

Conclusion

OD induced by anterior crossbite can lead to the anxiety-like behaviours. During this process, ncRNA also changes. CircRNA10039 and PTBP1 may play a role in OD-induced anxiety-like behaviours.

背景:咬合不协调(OD)可能诱发焦虑样行为,然而其潜在机制仍不清楚。在此,我们探讨了非编码 RNA(ncRNA)在 OD 诱导的焦虑样行为中的表达谱及其生物学功能和调控网络:C57BL/6小鼠前交叉咬合产生咬合不协调。行为测试、皮质酮(CORT)和血清素(5-HT)水平用于测量焦虑。此外,还使用 RNA 测序筛选所有差异表达(DE)的 ncRNA。此外,还通过 ENCORI 数据库预测了与 ncRNAs 相互作用的 RNA 结合蛋白,并使用 Western 印迹进行了确认:结果:行为测试和 CORT 的显着差异表明,OD 成功诱导了焦虑样行为。在 OD 小鼠中,ncRNA 明显失调。基因本体(GO)和京都基因组百科全书(KEGG)分析表明,DE ncRNA富集于焦虑相关通路。circRNA10039被上调,PTBP1被预测与circRNA10039相互作用。此外,KEGG通路分析表明,PTBP1可能与信使RNA生物发生和剪接体有关:结论:前交叉咬合诱发的 OD 可导致焦虑样行为。在此过程中,ncRNA也会发生变化。CircRNA10039和PTBP1可能在OD诱导的焦虑样行为中发挥作用。
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引用次数: 0
Oral hypofunction and social aspects in older adults visiting frailty outpatient clinic 在虚弱门诊就诊的老年人口腔功能低下和社交方面的问题。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-23 DOI: 10.1111/joor.13803
Koki Kawamura, Keisuke Maeda, Shuzo Miyahara, Akio Shimizu, Tatsuma Sakaguchi, Yuria Ishida, Hitoshi Kagaya, Yasumoto Matsui, Hidenori Arai, Naoharu Mori

Background

Oral and social problems can exacerbate long-term care. Understanding the relationship between social aspects and oral hypofunction can help identify high-risk factors for long-term care.

Objective

This study aimed to investigate the social aspects of oral hypofunction among medical outpatients.

Methods

This retrospective cross-sectional study included patients who visited an outpatient clinic for frailty. The oral function was assessed using seven items: oral hygiene, occlusal force, masticatory function, tongue-lip motor function, tongue pressure, oral dryness and swallowing function. Participants with three or more functional declines were classified as having ‘oral hypofunction’. Social aspects were assessed using 21 items in four categories: general resources, basic social needs, social resources and social behaviours/activities. We analysed the relationship between oral hypofunction and each social aspect.

Results

A total of 316 participants (age 78.5 ± 6.4 years) were included, and 128 (41%) had oral hypofunction. Participants with oral hypofunction were significantly more likely to have limited education, require long-term care, not use transportation, depend on others for shopping, not participate in events, lack association membership and not engage in charity or volunteer work. After logistic regression analysis, ‘long-term care’ and ‘no association membership’ remained significantly associated with oral hypofunction (odds ratios 2.3, 2.3; 95% CI 1.1–5.0, 1.1–4.7, respectively).

Conclusion

Participants with oral hypofunction faced challenges in ‘general resources’ and ‘social behaviour/activities’, which were linked to oral function issues. Future longitudinal studies are necessary to further investigate this relationship.

背景:口腔和社会问题会加剧长期护理。了解社会因素与口腔功能低下之间的关系有助于识别长期护理的高风险因素:本研究旨在调查门诊患者口腔功能低下的社会因素:这项回顾性横断面研究纳入了因体弱而到门诊就诊的患者。口腔功能通过七个项目进行评估:口腔卫生、咬合力、咀嚼功能、舌唇运动功能、舌压、口腔干燥和吞咽功能。有三项或三项以上功能下降的参与者被归类为 "口腔功能低下"。社会方面的评估使用了 21 个项目,分为四个类别:一般资源、基本社会需求、社会资源和社会行为/活动。我们分析了口腔功能减退与各社会方面之间的关系:共纳入 316 名参与者(年龄为 78.5 ± 6.4 岁),其中 128 人(41%)患有口腔功能低下。患有口腔功能低下的参与者更有可能受教育程度有限、需要长期护理、不使用交通工具、购物依赖他人、不参加活动、没有协会会员资格、不从事慈善或志愿者工作。经过逻辑回归分析,"需要长期护理 "和 "没有协会会员身份 "仍与口腔功能低下有显著关联(几率比分别为 2.3、2.3;95% CI 分别为 1.1-5.0、1.1-4.7):口腔功能低下的参与者在 "一般资源 "和 "社会行为/活动 "方面面临挑战,这与口腔功能问题有关。今后有必要开展纵向研究,进一步探究这种关系。
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引用次数: 0
Comparative evaluation of cognitive behavioural therapy versus standard treatment in temporomandibular disorders: A systematic review. 认知行为疗法与颞下颌关节紊乱症标准疗法的比较评估:系统综述。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-23 DOI: 10.1111/joor.13792
Sahana Shivakumar, Nishath Sayed Abdul, Bhuvan Jyoti, Veena Kalburgi, Marco Cicciù, Giuseppe Minervini

Background: Temporomandibular disorders (TMDs) are musculoskeletal and neuromuscular conditions affecting the temporomandibular joint and associated structures. Cognitive-behavioural therapy (CBT) has emerged as a potential intervention for TMDs, but its comparative effectiveness against standard treatments remains unclear. This systematic review aimed to evaluate and compare the efficacy of CBT versus standard treatment interventions in managing TMDs.

Methods: A comprehensive search was conducted across multiple databases using MeSH keywords and Boolean operators. Inclusion criteria encompassed clinical trials comparing CBT/CBT in combination with standard treatment interventions or a control group in individuals with TMDs. The primary outcome measured was pain. Secondary outcomes such as disability, depression and jaw function were also looked into. Two reviewers independently assessed for the eligibility of the articles and conducted data extraction. Quality assessments were performed using RoB 2.0 for randomised clinical trials.

Results: The initial search identified 623 articles, of which a total of eight clinical studies met the inclusion criteria and were included in the systematic review. Seven out of eight studies demonstrated improvements in outcomes related to TMD. Pain was significantly decreased in studies that showed a positive outcome. Jaw function, quality of life and psychological well-being were superior among individuals receiving CBT alone or in combination with conventional modalities, as well as hypnotic therapy coupled with CBT-based interventions. The quality of studies assessed showed all articles to be of good quality as per RoB-2 evaluation.

Conclusion: This systematic review highlights the potential benefits of CBT in managing TMDs, suggesting its effectiveness in improving pain outcomes and enhancing overall well-being. The findings indicate that CBT may be a valuable adjunct or alternative to standard treatment interventions for individuals with TMDs. However, further research with larger sample sizes and standardised outcome measures is warranted to establish definitive conclusions regarding the comparative efficacy of CBT versus standard treatments in TMD management.

背景:颞下颌关节紊乱症(TMDs)是一种影响颞下颌关节及相关结构的肌肉骨骼和神经肌肉疾病。认知行为疗法(CBT)已成为治疗 TMD 的一种潜在干预措施,但其与标准疗法的比较效果仍不明确。本系统性综述旨在评估和比较 CBT 与标准治疗干预措施在治疗 TMDs 方面的疗效:使用 MeSH 关键字和布尔运算符在多个数据库中进行了全面搜索。纳入标准包括比较 CBT/CBT 与标准治疗干预或对照组对 TMDs 患者的临床试验。测量的主要结果是疼痛。次要结果如残疾、抑郁和下颌功能也在考察之列。两名审稿人独立评估文章的合格性并进行数据提取。采用 RoB 2.0 对随机临床试验进行质量评估:初步检索发现了 623 篇文章,其中共有 8 项临床研究符合纳入标准,并被纳入系统综述。八项研究中的七项证明了与 TMD 相关的结果有所改善。在取得积极成果的研究中,疼痛明显减轻。在单独接受 CBT 治疗或与传统治疗方法相结合,以及在接受催眠治疗的同时接受 CBT 干预治疗的患者中,下颌功能、生活质量和心理健康均有改善。根据RoB-2评估,所有文章的研究质量均为良好:本系统性综述强调了 CBT 在治疗 TMD 方面的潜在益处,表明 CBT 在改善疼痛效果和提高整体健康水平方面非常有效。研究结果表明,CBT 可能是 TMDs 患者标准治疗干预的一种有价值的辅助或替代方法。不过,要想就 CBT 与标准治疗在 TMD 管理中的疗效比较得出明确结论,还需要进行更多的样本量和标准化结果测量的进一步研究。
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引用次数: 0
Risk factors associated with temporomandibular joint disorder: A mendelian randomization analysis 与颞下颌关节紊乱有关的风险因素:孟德尔随机分析
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-23 DOI: 10.1111/joor.13795
Qinghan Yan, Lingzi Liao, Dengqi He

Background

Temporomandibular joint disorder (TMD), a prevalent orofacial disorder with complex aetiologies and considerable socioeconomic costs. This underscores the critical importance of developing a comprehensive understanding of the risk factors associated with TMD, as existing research is hindered by deficiencies in establishing causal relationships and the limitations of traditional research methodologies.

Objectives

This research explores the causal link between certain risk factors and temporomandibular joint disorder (TMD) through Mendelian randomization (MR), providing multidimensional perspectives in addressing this worldwide health issue.

Methods

Utilizing instrumental variables, we applied advanced statistical methods, including the weighted median, inverse variance weighted (IVW) and MR-Egger, to evaluate the impact of twelve potential risk factors on TMD.

Results

Our results identified a significant positive association of TMD with malocclusion (p < .001), sleeping disorders (p = .006), anxiety (p = .002), major depression (p = .0002), daily cigarettes consumption (p = .029) and autoimmune diseases (p = .039). Conversely, a negative association was observed with educational attainment (p = .003).

Conclusion

These findings suggest that malocclusion, sleeping disorders, anxiety, major depression, daily cigarettes consumption and autoimmune diseases, could potentially increase TMD risk while educational attainment might mitigate its increase. No direct causal relationships were established between serum 25-hydroxyvitamin D levels, menopause, frequent alcohol consumption, coffee intake and severely worn dentition and TMD.

背景:颞下颌关节紊乱症(TMD)是一种常见的口腔疾病,病因复杂,社会经济损失巨大。由于现有研究在建立因果关系方面存在缺陷,且传统研究方法存在局限性,因此全面了解与 TMD 相关的风险因素就显得尤为重要:本研究通过孟德尔随机法(MR)探讨了某些风险因素与颞下颌关节紊乱症(TMD)之间的因果关系,为解决这一世界性健康问题提供了多维视角:利用工具变量,我们采用了先进的统计方法,包括加权中位数、反方差加权(IVW)和MR-Egger,来评估12个潜在风险因素对TMD的影响:结果:我们发现 TMD 与错颌畸形有明显的正相关性(p 结论:这些研究结果表明,错颌畸形与 TMD 有明显的正相关性:这些研究结果表明,错牙合畸形、睡眠障碍、焦虑症、重度抑郁症、日常吸烟和自身免疫性疾病可能会增加 TMD 的风险,而教育程度可能会降低其风险的增加。血清中 25- 羟维生素 D 水平、更年期、经常饮酒、咖啡摄入量和严重磨损的牙齿与 TMD 之间没有直接的因果关系。
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引用次数: 0
Sleep-related bruxism, microarousals and oxyhaemoglobin desaturations in sleep stages: A cross-sectional study in a large apnoeic population 与睡眠有关的磨牙症、微量磨牙和睡眠阶段氧合血红蛋白不饱和:一项针对大量呼吸暂停人群的横断面研究。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-21 DOI: 10.1111/joor.13813
Silvana Alkmim de Miranda Diniz, Regina de Magalhães Lopes, Luciana Macedo Guedes, Fábio Fernandes Borém Bruzinga, Karolina Kristian de Aguilar Seraidarian, Vinícius de Magalhães Barros, Maria Letícia de Barros Massahud, Paulo Isaias Seraidarian

Background

Sleep-related bruxism (SB) is the habit of grinding or clenching the teeth during sleep, mediated by the non-peripheral central nervous system.

Purpose

The objectives of this cross-sectional study were to evaluate associations between SB, microarousals and oxyhaemoglobin desaturations and to compare the frequency of SB and microarousals in sleep stages, in an apnoeic population.

Methods

Two hundred and forty individuals composed the sample, who underwent a single full-night polysomnography. Self-reports and clinical inspections were not considered for assessing SB. The polysomnographic assessment of SB was performed using electrodes placed on masseter muscles and chin. SB was defined as more than two events of rhythmic masticatory muscle activity per hour of sleep. Microarousals were considered when there were abrupt changes in electroencephalogram frequencies, without complete awakening, lasting from 3 to 15 s. Oxyhaemoglobin desaturations were defined as significant drops (≥3%) in basal oxygen saturations. With these data, SB, microarousals and oxyhaemoglobin desaturations were evaluated and submitted to statistical analysis.

Results

Statistically significant differences were observed between bruxers and non-bruxers when comparing the rates of microarousals (p < .001) and oxyhaemoglobin desaturations (p = .038). There was a higher number of SB and microarousals in NREM (non-rapid eye movement) two sleep stage (p < 0.001). Bruxers had a greater risk of higher numbers of microarousals (OR = 1.023; p = .003), which did not occur for oxyhaemoglobin desaturations (OR = 0.998; p = .741).

Conclusions

A higher number of microarousals presents relationship with SB; associations between SB and oxyhaemoglobin desaturations remained inconclusive; higher frequency of SB and microarousals was observed in NREM 2 sleep stage.

背景:目的:本横断面研究的目的是评估睡眠相关磨牙症(SB)、微量磨牙和氧合血红蛋白不饱和之间的关联,并比较呼吸暂停人群在睡眠阶段出现 SB 和微量磨牙的频率:方法:抽取 240 人作为样本,对其进行一次整夜多导睡眠监测。评估 SB 时不考虑自我报告和临床检查。对 SB 的多导睡眠图评估是通过放置在颌下肌肉和下巴上的电极进行的。每小时睡眠中出现两次以上有节律的咀嚼肌活动即为SB。如果脑电图频率发生突然变化,但没有完全唤醒,持续时间在 3 到 15 秒之间,则视为微唤醒。氧血红蛋白不饱和是指基础血氧饱和度显著下降(≥3%)。根据这些数据,对 SB、微量哮喘和氧合血红蛋白不饱和进行了评估和统计分析:结果:在比较微量磨牙率时,磨牙者和非磨牙者之间存在明显的统计学差异(p 结论:磨牙者的微量磨牙率更高,而非磨牙者的微量磨牙率更低:较多的微动声与SB有关;SB与氧合血红蛋白不饱和之间的关系仍不确定;在NREM 2睡眠阶段观察到较高频率的SB和微动声。
{"title":"Sleep-related bruxism, microarousals and oxyhaemoglobin desaturations in sleep stages: A cross-sectional study in a large apnoeic population","authors":"Silvana Alkmim de Miranda Diniz,&nbsp;Regina de Magalhães Lopes,&nbsp;Luciana Macedo Guedes,&nbsp;Fábio Fernandes Borém Bruzinga,&nbsp;Karolina Kristian de Aguilar Seraidarian,&nbsp;Vinícius de Magalhães Barros,&nbsp;Maria Letícia de Barros Massahud,&nbsp;Paulo Isaias Seraidarian","doi":"10.1111/joor.13813","DOIUrl":"10.1111/joor.13813","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Sleep-related bruxism (SB) is the habit of grinding or clenching the teeth during sleep, mediated by the non-peripheral central nervous system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The objectives of this cross-sectional study were to evaluate associations between SB, microarousals and oxyhaemoglobin desaturations and to compare the frequency of SB and microarousals in sleep stages, in an apnoeic population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Two hundred and forty individuals composed the sample, who underwent a single full-night polysomnography. Self-reports and clinical inspections were not considered for assessing SB. The polysomnographic assessment of SB was performed using electrodes placed on masseter muscles and chin. SB was defined as more than two events of rhythmic masticatory muscle activity per hour of sleep. Microarousals were considered when there were abrupt changes in electroencephalogram frequencies, without complete awakening, lasting from 3 to 15 s. Oxyhaemoglobin desaturations were defined as significant drops (≥3%) in basal oxygen saturations. With these data, SB, microarousals and oxyhaemoglobin desaturations were evaluated and submitted to statistical analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Statistically significant differences were observed between bruxers and non-bruxers when comparing the rates of microarousals (<i>p</i> &lt; .001) and oxyhaemoglobin desaturations (<i>p</i> = .038). There was a higher number of SB and microarousals in NREM (non-rapid eye movement) two sleep stage (<i>p</i> &lt; 0.001). Bruxers had a greater risk of higher numbers of microarousals (OR = 1.023; <i>p</i> = .003), which did not occur for oxyhaemoglobin desaturations (OR = 0.998; <i>p</i> = .741).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A higher number of microarousals presents relationship with SB; associations between SB and oxyhaemoglobin desaturations remained inconclusive; higher frequency of SB and microarousals was observed in NREM 2 sleep stage.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":"51 10","pages":"2140-2149"},"PeriodicalIF":3.1,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons to be learned when designing comprehensible patient-oriented online information about temporomandibular disorders. 在设计以患者为导向的可理解的颞下颌关节紊乱网上信息时应吸取的经验教训。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-21 DOI: 10.1111/joor.13798
Hande Uzunçıbuk, Maria Maddalena Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: Temporomandibular disorders (TMD) are a prevalent ailment with a global impact, affecting a substantial number of individuals. While some individuals are receiving treatment from orthodontists for TMD, a significant proportion of individuals obtain knowledge through websites.

Objectives: Our purpose had been to evaluate, from a patient-oriented perspective, the readability of home pages of websites scored in the 10 most prominent devoted to TMD. We also determined what level of education would have been needed to get an overview of the information on the websites under scrutiny. This approach ensures that our findings are centred on the patient experience, providing insights into how accessible and understandable websites about TMD.

Methods: We determined the top 10 patient-focused English language websites by searching for 'temporomandibular disorders' in the 'no country redirect' plugin of the Google Chrome browser (www.google.com/ncr). The readability of the texts was assessed using the Gunning fog index (GFI), Coleman Liau index (CLI), Automated readability index (ARI) Simple Measure of Gobbledygook (SMOG), Flesch Kincald grade level (FKGL), Flesh reasing ease (FRE) (https://readabilityformulas.com).

Results: The mean Flesch reading ease index score was determined to be 48.67, accompanied by a standard deviation of 15.04 and these websites require an average of 13.49 years of formal education (GFI), with a standard deviation of 2.62, for ease of understanding.

Conclusion: Our research indicates that a significant proportion of websites related to TMD can be defined as a level of complexity that exceeds the ability to read comprehension of the general population.

背景:颞下颌关节紊乱症(TMD)是一种具有全球性影响的普遍疾病,影响着相当多的人。虽然有些人正在接受正畸医生提供的 TMD 治疗,但很大一部分人是通过网站获得相关知识的:我们的目的是从面向患者的角度出发,对 10 个最著名的 TMD 网站首页的可读性进行评估。我们还确定了需要达到什么样的教育水平才能了解所审查网站的信息概况。这种方法可确保我们的研究结果以患者体验为中心,深入了解有关 TMD 的网站的可访问性和可理解性:我们通过在谷歌 Chrome 浏览器的 "无国家重定向 "插件中搜索 "颞下颌关节紊乱症",确定了前 10 个以患者为中心的英文网站 (www.google.com/ncr)。文章的可读性使用贡宁雾指数(GFI)、科尔曼-廖指数(CLI)、自动可读性指数(ARI)、简单阅读障碍测量法(SMOG)、弗莱什-金卡尔德等级水平(FKGL)、肉体阅读难易度(FRE)(https://readabilityformulas.com)进行评估。结果:这些网站平均需要 13.49 年的正规教育 (GFI),标准差为 2.62,才能易于理解:我们的研究表明,相当一部分与 TMD 相关的网站的复杂程度超出了普通人的阅读理解能力。
{"title":"Lessons to be learned when designing comprehensible patient-oriented online information about temporomandibular disorders.","authors":"Hande Uzunçıbuk, Maria Maddalena Marrapodi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.1111/joor.13798","DOIUrl":"https://doi.org/10.1111/joor.13798","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) are a prevalent ailment with a global impact, affecting a substantial number of individuals. While some individuals are receiving treatment from orthodontists for TMD, a significant proportion of individuals obtain knowledge through websites.</p><p><strong>Objectives: </strong>Our purpose had been to evaluate, from a patient-oriented perspective, the readability of home pages of websites scored in the 10 most prominent devoted to TMD. We also determined what level of education would have been needed to get an overview of the information on the websites under scrutiny. This approach ensures that our findings are centred on the patient experience, providing insights into how accessible and understandable websites about TMD.</p><p><strong>Methods: </strong>We determined the top 10 patient-focused English language websites by searching for 'temporomandibular disorders' in the 'no country redirect' plugin of the Google Chrome browser (www.google.com/ncr). The readability of the texts was assessed using the Gunning fog index (GFI), Coleman Liau index (CLI), Automated readability index (ARI) Simple Measure of Gobbledygook (SMOG), Flesch Kincald grade level (FKGL), Flesh reasing ease (FRE) (https://readabilityformulas.com).</p><p><strong>Results: </strong>The mean Flesch reading ease index score was determined to be 48.67, accompanied by a standard deviation of 15.04 and these websites require an average of 13.49 years of formal education (GFI), with a standard deviation of 2.62, for ease of understanding.</p><p><strong>Conclusion: </strong>Our research indicates that a significant proportion of websites related to TMD can be defined as a level of complexity that exceeds the ability to read comprehension of the general population.</p>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of ultrasonography in the diagnosis of temporomandibular joint disorders: A systematic review and meta-analysis. 超声波检查在诊断颞下颌关节紊乱中的有效性:系统回顾和荟萃分析。
IF 3.1 3区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-07-18 DOI: 10.1111/joor.13807
Mahmud Uz Zaman, Mohammad Khursheed Alam, Nasser Raqe Alqhtani, Mana Alqahtani, Mohammed J Alsaadi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini

Background: Temporomandibular disorders (TMDs) pose diagnostic challenges, and selecting appropriate imaging modalities is crucial for accurate assessment. This study aimed to compare the diagnostic accuracy and efficacy of ultrasonography (US) and magnetic resonance imaging (MRI) in identifying TMDs.

Methods: A comprehensive meta-analysis was conducted, including studies that compared US and MRI for TMJ disorder assessments. Fixed-effects models were utilized to calculate pooled odds ratios (ORs) and relative risks (RRs) with 95% confidence intervals (CIs). Heterogeneity was assessed using the chi-squared test and I2 statistic. Newcastle-Ottawa scale was used to assess the methodological quality of the studies included.

Results: Six studies were included, involving a total of 281 participants. The meta-analysis demonstrated that MRI was statistically somewhat better than US in identifying TMJ disorders. The summary OR was 0.64 (95% CI: 0.46-0.90), and the summary RR was 0.80 (95% CI: 0.68-0.95). Heterogeneity among the studies was low (χ2 = 2.73, df = 5, p = .74; I2 = 0%). Demographic variables revealed variations in sample size, gender ratio and mean age across the studies.

Conclusion: This meta-analysis provides evidence that MRI may be more effective than US in diagnosing TMDs. However, the study is limited by the small number of included studies and variations in demographic variables and study designs. Future research with larger samples and standardised protocols is essential to confirm and strengthen these findings. Understanding the diagnostic accuracy of MRI and US for TMJ disorders will aid clinicians in making informed decisions for effective TMJ disorder assessments and patient management.

背景:颞下颌关节紊乱症(TMD)给诊断带来了挑战,而选择适当的成像方式对于准确评估至关重要。本研究旨在比较超声波成像(US)和磁共振成像(MRI)在识别 TMD 方面的诊断准确性和有效性:方法: 我们进行了一项全面的荟萃分析,包括比较 US 和 MRI 对颞下颌关节紊乱进行评估的研究。采用固定效应模型计算汇总的几率比(ORs)和相对风险(RRs)及95%置信区间(CIs)。异质性采用卡方检验和 I2 统计量进行评估。纽卡斯尔-渥太华量表用于评估纳入研究的方法学质量:结果:共纳入六项研究,涉及 281 名参与者。荟萃分析表明,在识别颞下颌关节紊乱方面,磁共振成像在统计学上略胜于US。总OR为0.64(95% CI:0.46-0.90),总RR为0.80(95% CI:0.68-0.95)。研究之间的异质性较低(χ2 = 2.73, df = 5, p = .74; I2 = 0%)。人口统计学变量显示,各研究的样本量、性别比例和平均年龄存在差异:这项荟萃分析提供的证据表明,磁共振成像在诊断 TMD 方面可能比 US 更有效。结论:这项荟萃分析提供了磁共振成像在诊断 TMD 方面可能比 US 更有效的证据。然而,由于纳入的研究数量较少,且人口统计学变量和研究设计存在差异,因此该研究存在局限性。未来的研究必须使用更多的样本和标准化的方案来证实和加强这些发现。了解 MRI 和 US 对颞下颌关节紊乱的诊断准确性将有助于临床医生做出明智的决定,从而有效地评估颞下颌关节紊乱和管理患者。
{"title":"Effectiveness of ultrasonography in the diagnosis of temporomandibular joint disorders: A systematic review and meta-analysis.","authors":"Mahmud Uz Zaman, Mohammad Khursheed Alam, Nasser Raqe Alqhtani, Mana Alqahtani, Mohammed J Alsaadi, Vincenzo Ronsivalle, Marco Cicciù, Giuseppe Minervini","doi":"10.1111/joor.13807","DOIUrl":"https://doi.org/10.1111/joor.13807","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMDs) pose diagnostic challenges, and selecting appropriate imaging modalities is crucial for accurate assessment. This study aimed to compare the diagnostic accuracy and efficacy of ultrasonography (US) and magnetic resonance imaging (MRI) in identifying TMDs.</p><p><strong>Methods: </strong>A comprehensive meta-analysis was conducted, including studies that compared US and MRI for TMJ disorder assessments. Fixed-effects models were utilized to calculate pooled odds ratios (ORs) and relative risks (RRs) with 95% confidence intervals (CIs). Heterogeneity was assessed using the chi-squared test and I<sup>2</sup> statistic. Newcastle-Ottawa scale was used to assess the methodological quality of the studies included.</p><p><strong>Results: </strong>Six studies were included, involving a total of 281 participants. The meta-analysis demonstrated that MRI was statistically somewhat better than US in identifying TMJ disorders. The summary OR was 0.64 (95% CI: 0.46-0.90), and the summary RR was 0.80 (95% CI: 0.68-0.95). Heterogeneity among the studies was low (χ<sup>2</sup> = 2.73, df = 5, p = .74; I<sup>2</sup> = 0%). Demographic variables revealed variations in sample size, gender ratio and mean age across the studies.</p><p><strong>Conclusion: </strong>This meta-analysis provides evidence that MRI may be more effective than US in diagnosing TMDs. However, the study is limited by the small number of included studies and variations in demographic variables and study designs. Future research with larger samples and standardised protocols is essential to confirm and strengthen these findings. Understanding the diagnostic accuracy of MRI and US for TMJ disorders will aid clinicians in making informed decisions for effective TMJ disorder assessments and patient management.</p>","PeriodicalId":16605,"journal":{"name":"Journal of oral rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of oral rehabilitation
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