Journal of oral rehabilitation最新文献

Objectives: One approach for improving oral health is focusing on oral health literacy (OHL). In this study, we aimed to investigate the association between OHL and oral health-related quality of life (OHRQoL) and to identify relevant OHL intervention targets that can be used to improve oral health.

Methods: We performed a cross-sectional questionnaire study among 1889 10th grade female students in the Eastern Province of the Kingdom of Saudi Arabia (KSA). We then assessed OHL using the Arabic version of the short version of the Health Literacy in Dentistry scale (A-HeLD-14). OHRQoL was assessed using the 14-item oral health impact profile (OHIP-14). Information on socio-demographics and oral health-related behaviours (e.g., toothbrushing, sugary diet consumption and dental attendance) was also collected. The relationship between OHL and OHRQoL was investigated using binary logistic regression adjusted for sociodemographic information and oral health-related behaviours.

Results: In both the adjusted and unadjusted models, poor OHL was significantly associated with OHRQoL problems (odds ration [OR] = 2.90, p < 0.001). Having any OHL problem was significantly associated with having an OHRQoL problem (p < 0.001). The ORs were highest for the domains of financial barriers (OR = 2.49, p < 0.001) and receptivity (OR = 2.16, p < 0.001).

Conclusion: Interventions targeted at individuals with low OHL are crucial to improving OHRQoL in the population. The most relevant interventions concern (a) dedicating time and attention to oral health and (b) financial barriers.

The idea of classifying and defining bruxism according to ontological principles may be interesting, but currently we just do not have enough information to label in a black or white manner the many facets of bruxism. In an era in which general knowledge on bruxism by the dental communities is surely in need of improvement, efforts to clarify the road map tracked by the current panelists who drafted the definition should be appraised carefully. The recent introduction of a standardized multidimensional evaluation system (i.e., Standardized Tool for the Assessment of Bruxism [STAB]) and a screening instrument for bruxism (i.e., BruxScreen) should be viewed as the starting points to enter a new era in the discipline of bruxism, in which non-hierarchical and non-preconceived approaches are used to collect data. Artificial intelligence strategies to mine data gathered with the above instruments might help building predictive models along the etiology-status-consequences trajectory, as recently suggested in a model for awake bruxism metrics. Until then, proposals to adopt ontological principles to classify bruxism will be merely based on speculations rather than on facts.

Background: Anterior disc displacement (ADD) is the most common type of temporomandibular joint (TMJ) internal derangement and may lead to condylar resorption (CR) during the adolescence period, but the specific malocclusion associated with ADD and CR remains unclear.

Objective: This study aimed to investigate the malocclusion associated with TMJ ADD and CR in adolescents.

Methods: This cross-sectional study included a clinical examination of adolescent patients aged 11-19 years. Magnetic resonance imaging (MRI) was used to diagnose both TMJ ADD and CR. Occlusal measurements were obtained and analysed using 3D scanning models.

Results: A total of 242 adolescent patients (53 males and 189 females) underwent TMJ MRI examination and dental occlusion scanning. The prevalence of anterior disc displacement without reduction (ADDwoR) was higher in females than that in males (OR > 1, p < 0.05). Deep overbite and posterior scissor bite were significantly associated with anterior disc displacement with reduction (ADDwR), while Angle Class II malocclusion, anterior open bite and posterior scissor bite were significantly associated with ADDwoR (OR > 1, p < 0.05). Adolescents with excessive overjet and anterior open bite were at a higher risk of CR (OR > 1, p < 0.05), whereas those with deep overbite and individual crossbite had a lower risk of CR (OR < 1, p < 0.05).

Conclusion: Our study offers valuable insights into the association between deep overbite, posterior scissor bite, Angle Class II malocclusion, anterior open bite, excessive overjet and the ADD and CR in adolescents. Orthodontic treatment for adolescent patients should prioritise the health of the TMJ, particularly for these types of malocclusion.

Background: Sedentary work is a potential health risk factor and may exacerbate painful complaints, while physical activity may serve as a preventive factor for the onset and worsening of musculoskeletal disorders. However, there is scarce evidence on how engaging in leisure physical activity may influence the reporting of temporomandibular dysfunction (TMD) symptoms.

Objective: To assess the association between the level of physical activity and TMD symptoms in office workers.

Methods: This is a cross-sectional study, 225 office workers of both sexes, aged over 18 years, participated in the study. The mean age was 33.65 (± 9.31) years, with a predominantly female sample (67.1%). The TMD Pain Screener determined the presence/absence of TMD symptoms, and the Baecke Habitual Physical Activity Questionnaire (BQHPA) determined the level of physical activity as high/moderate/low.

Results: 25.3% of the total sample presented TMD symptoms, of which 19.1% were women. The total BQHPA score showed that 35.5% of the total sample had a high level of physical activity. Regression analysis revealed no association between TMD symptoms and the level of leisure physical activity.

Conclusion: Office workers exhibited a low prevalence of TMD symptoms, and the presence of TMD symptoms was not associated with the level of physical activity.

Background: Psychosocial health affects oral health-related quality of life. Pregnancy, as a special time for women, produces significant psychological changes. However, the relationship between mental health during pregnancy and oral health-related quality of life is unclear.

Objective: The study aims to explore the association between fear of childbirth and investigate the mediating effect of pregnancy anxiety.

Methods: Using a cross-sectional design, 478 pregnant women were recruited and evaluated using the Fear of Birth Scale, the Pregnancy-Related Anxiety Questionnaire and the Oral Health Impact Profile-14. Multiple linear regressions were performed to evaluate the relationship between fear of childbirth and oral health-related quality of life. PROCESS software was applied to assess the mediating effect of pregnancy anxiety.

Results: Both fear of childbirth and pregnancy anxiety were negative correlation with oral health-related quality. Pregnancy anxiety mediated 40% of the association between fear of childbirth and oral health-related quality of life (β = 0.072, SE = 0.030, 95% CI [0.015, 0.131]).

Conclusions: Pregnancy anxiety mediates the relationship between fear of childbirth and oral health-related quality of life in pregnant women. To improve the oral health-related quality of life among pregnant women, relevant healthcare workers should actively help pregnant women to improve psychological health.

Background: Dental pulp stem cells (DPSCs) are widely used in research on dental tissue regeneration and systemic disease treatment. However, the oxidative microenvironment often causes cellular senescence, leading to decreased function. Our previous study demonstrated that pleiotrophin (PTN), a secreted extracellular matrix-associated protein, could rescue the proliferative capacity and osteogenic differentiation of replicative senescent DPSCs.

Objective: This study aimed to explore the influence and mechanism of PTN on dental pulp stem cells under H₂O₂-induced oxidative microenvironment.

Materials and methods: DPSCs isolated from human third molars were treated with 100 μm H₂O₂ for 4 h, mimicking the oxidative microenvironment. To investigate the influence of PTN on DPSC under H₂O₂-induced oxidative microenvironment, 50 pg/mL PTN was added in the culture medium for 48 h. RT-qPCR, western blotting, SA-β-gal staining, intracellular ROS production and immunofluorescence staining assays were used to analyse the cellular senescence, osteogenic differentiation capacity, oxidative stress conditions and possible mechanism.

Results: H₂O₂ treatment increased the ratio of SA-β-gal-positive DPSCs and upregulated the senescence-related gene expression, including P53, P21 and P16. PTN pretreatment downregulated the ratio of SA-β-gal-positive DPSCs and the expression of these genes. Besides, PTN pretreatment partially reversed the H₂O₂-induced decreased osteogenic differentiation potential of DPSCs, total antioxidant capacity and Nrf2 and HO-1 mRNA expression in DPSCs. Western blotting and immunofluorescent staining results indicated that PTN pretreatment enhanced the Nrf2 nuclear translocation under oxidative stress conditions and observable higher fluorescence signals in the nucleus denoted PTN and Nrf2 colocalisation. Western blotting results showed that PTN reversed the decreased expression of p-AKT in the H₂O_2-induced oxidative environment. However, the PI3K inhibitor LY294002 blocked the upregulated levels of total Nrf2. Immunofluorescence staining displayed that LY294002 also inhibited the nuclear translocation of Nrf2 which was enhanced under PTN pretreatment.

Conclusions: This study demonstrated that PTN could prevent senescent damage induced by H₂O₂ on DPSCs, mainly by combining with Nrf2 and enhancing its nuclear translocation.

Background: Class II occlusion is associated with narrow dimensions of the maxillary dental arch and hard palate (maxillary dimensions), which may increase the risk of narrow upper airways and sleep-disordered breathing (SDB).

Objectives: The aim was to compare maxillary dental arch and hard palate dimensions in children with Class II and large overjet ≥ 6 mm (study group) to a control group with neutral occlusion and to examine the relation between SDB and maxillary dimensions.

Methods: The study group included 37 children (19 boys; 18 girls; median age 12.3 years) and the control group included 32 children (16 boys; 16 girls; median age 12.2 years). SDB was assessed by respiratory polygraphy, the distances between maxillary canines and first permanent molars were measured by intraoral scans and the general relation between SDB and maxillary dimensions was analysed.

Results: Significantly smaller distances between both canines and first molars (p ≤ 0.001) were found in the study group. No significant differences in dimensions of the hard palate or SDB were found between the groups but the snore index tended to be higher in the study group (p = 0.051). No general significant associations between SDB measurements and maxillary dimensions were found in the total group of participants.

Conclusions: Significantly reduced transversal dimensions of the maxillary dental arch were found in the study group with Class II occlusion compared to controls. No significant difference regarding dimensions of the hard palate or SDB between the groups was found nor between SDB and maxillary dimensions. However, intraoral scans may be useful in risk assessment of early signs of paediatric SDB in orthodontic patients.

Trial registration: ClinicalTrials.gov identifier: NCT04964830.

Objective: This study aimed to correlate the bite/occlusal force measurements obtained through two methods: a hydraulic pressure gauge with a biting transducer (GM-10), and a computer-assisted device that records occlusal force on a pressure-sensitive film (Prescale II).

Methods: Healthy, dentate volunteers were recruited. Participants' demographic data included age, sex, number of teeth present, presence of oral pain, history of prior orthodontic treatment and presence of parafunction. Bite/occlusal force measurements were recorded for each participant using the GM-10 and the Prescale II devices. Linear Mixed-effect model regression was performed with the significance set at p < 0.05.

Results: Forty-six volunteers (women = 25, men = 21; mean-age = 30.9 ± 9.3 years) participated. 54.3% and 34.8% presented with 28 and 29-32 teeth, respectively. 60.9% and 26.1% of the participants reported previous orthodontic treatment and oral parafunction. The overall mean GM-10 measurements recorded were 333.0 ± 192, 276 ± 167, 208 ± 134, 142 ± 103 Newtons, for the 2nd and 1st molars, 2nd and 1st premolars, respectively. GM-10 measurements were associated with the tooth position (p < 0.001) and the number of teeth (p < 0.001). The mean Prescale II measurements obtained with and without filter were 826 ± 594 and 1049 ± 595 Newtons, respectively, which were positively correlated with the occlusal contact area (r = 0.765; p < 0.001) and GM-10 (r = 0.245; p = 0.019). The regression analysis for dependent repeated data confirmed the significant effect of the GM-10 measurements (bite force) and the occlusal contact area on the Prescale II measurements.

Conclusion: Within the limitations of this study, it can be concluded that the correlation between bite force measurements carried out by GM-10 and Dental Prescale II was low and may not be considered interchangeable methods. The maximum bite force measured in isolated point contacts was a predictive factor of the occlusal force distributed over the entire arch. Further studies are warranted to explore this influence in the clinical implications of these findings.

Background: Literature searching is one of the main determinants of a systematic review (SR)'s reliability. Thus, adequate reporting of search strategy is essential for the critical appraisal of SRs and evidence-based practice.

Objectives: To assess the reporting quality of search strategy among SRs in leading dental specialty journals, and to identify factors associated with quality of reporting.

Materials and methods: Six leading dental journals with the highest 5-year impact factors in their respective specialty were included. A hand search was undertaken to identify SRs published between 2017 and 2022. Full texts were reviewed by two authors to identify eligible SRs. Reporting quality was assessed and scored using a modified 15-item checklist based on Preferred Reporting Items for Systematic reviews and Meta-Analyses literature search extension (PRISMA-S). Univariable and multivariable linear regression analyses were then performed.

Settings and sample population: A total of 152 reviews were included and assessed.

Results: As for information sources, only 'citation searching' was adequately reported in most reviews 110 (72.4%). Only 23 (15.1%) of the included reviews clearly reported search strategies. Information about peer review was provided in only 10 reviews (6.6%). Only 91 (59.9%) of the included reviews documented the total records clearly. According to multivariable regression analysis, industrial funding (p = 0.012), registration (p = 0.013) and librarian involvement (p = 0.004) were significantly associated with higher reporting quality.

Conclusions: The reporting quality of search strategy among SRs in leading dental specialty journals is suboptimal. Researchers, librarians, reviewers and journal editors in dentistry need to be familiar with the PRISMA-S checklist, and make concerted efforts to improve the reporting of search strategy in SRs.