Journal of oral rehabilitation最新文献

Objective: This review summarises the role of Gli1⁺ (Glioma-associated oncogene homologue 1) mesenchymal stem cells in craniofacial growth and development or tissue repair, and their application in the treatment of some diseases.

Design: The search for this narrative review was conducted in PubMed and Web of Science using relevant keywords, including checking reference lists of journal articles by hand searching.

Results: Gli1⁺ mesenchymal stem cells play an important role in the growth and development of the skull, tooth, periodontium and mandibular condyle. They can be applied to the treatment of pulp and periodontal diseases, temporomandibular joint osteoarthritis and other diseases.

Conclusions: Gli1⁺ mesenchymal stem cells are crucial for the development and repair of craniofacial tissue.

Background: There is limited understanding of how temporomandibular disorder (TMD) symptoms, psychological distress, and well-being are related to each other and to OHRQoL in Chinese young adults.

Objectives: This study aimed to identify correlations between TMD symptom severity, psychological status, and OHRQoL while also examining factors associated with low OHRQoL.

Methods: Participants, recruited from a major university in the capital city, completed a survey that included demographics, the Chinese versions of the expanded five TMD symptoms (5Ts) screener, Depression, Anxiety, Stress Scales-21 (DASS-21), Ryff's Scales of Psychological Well-being-18 (SPWB-18), and Oral Health Impact Profile for TMDs (OHIP-TMD). Data were analysed using Chi-square and Kruskal-Wallis/Mann-Whitney U tests, Spearman's correlation, and logistic regression (α = 0.05).

Results: The study sample consisted of 414 individuals (mean age 22.0 years [SD 2.1], 77.8% female). Among them, 23.4%, 22.2%, 15.7%, and 38.6% had no (NT), intra-articular (IT), pain-related (PT), and combined (CT) TMD symptoms, respectively. Significant differences were observed in global TMD severity (CT>IT, PT>NT), global distress (CT>IT, NT), and OHRQoL (CT>IT, PT, NT), but not global well-being. Global TMD severity was significantly, albeit weakly, correlated with global distress (r_s  = 0.32) and global well-being (r_s  = -0.12). Global distress, in turn, showed a significant but weak negative association with global well-being (r_s  = -0.34). Both global TMD severity and global distress exhibited moderate correlations with global OHIP (r_s  = 0.63/0.42).

Conclusions: Global TMD severity, incorporating symptom duration, frequency, intensity, and interference, was the main determinant of low OHRQoL in Chinese young adults.

Background: Temporomandibular disorder (TMD) is the main chronic pain that affects the face, and it is associated with dietary changes due to pain and dysfunction. However, there is a scarcity of studies on its impact on nutrition and vice versa.

Objectives: To assess and compare the intake of energy and nutrients among chronic TMD myalgia and asymptomatic women and to evaluate data according to dietary reference intakes (DRI) and the World Health Organization (WHO) values.

Methods: In this analytical cross-sectional study, 84 female subjects were evaluated according to the diagnostic criteria of TMD (DC/TMD) and allocated into two groups: asymptomatic group (n = 16) and TMD group (n = 68). Participants were assessed using three 24-h dietary recalls and then analysed for energy, macro and micronutrient content (Nutwin programme). The multiple source method programme was used to estimate participants' usual dietary intake. Usual energy and nutrients intake were also analysed according to the DRI and WHO values. The obtained data were analysed using SPSS 25.0 software. The data were considered significant when the p values were ≤ 0.05.

Results: The TMD group showed lowered usual intake of cholesterol, sodium, omega-3, omega-6, folate, magnesium, selenium and increased usual intake of trans fat. The TMD group showed a higher prevalence of inadequacy of selenium and folate intake.

Conclusion: Dietary intake inadequacies were observed in both groups; however, TMD women showed a significantly lower intake of several nutrients. Long-term dietary assessment is suggested to accurately investigate the relationship between TMD and nutrient deficiencies.

Background: The complex association between COVID-19 and psychological factors may significantly impact oral health, including oral health-related quality of life (OHRQoL). Despite their interconnected nature, literature regarding their collective impact on OHRQoL is limited.

Objective: This study aims to assess the independent and interactive effects of COVID-19 infection and psychological factors on OHRQoL.

Materials and methods: The cross-sectional study included 158 participants from a health centre in Yangon city. Participants were categorised into three groups based on their COVID-19 infection history, hospitalisation and oxygen supply: 'not experienced', 'experienced, non-hospitalised' and 'experienced, hospitalised'. Validated instruments, including Depression, Anxiety and Stress Scale-21 (DASS-21) to measure emotional states and the Oral Health Impact Profile-14 (OHIP-14) to assess OHRQoL, were employed. Descriptive statistics, Mann-Whitney U test, Kruskal-Wallis test, linear regressions and interaction analysis were computed.

Results: The median OHIP-14 score was 7.2. Among 85 confirmed COVID-19 cases, 38.8% (n = 33) received hospitalisation and oxygen supply. Multivariable regression analysis identified 'experienced, hospitalised' (95% CI: 6.36, 11.76), difficulty falling asleep (95% CI: 2.65, 7.18), depressive symptoms (95% CI: 7.38, 12.44), anxiety symptoms (95% CI: 2.93, 7.52) and stress symptoms (95% CI: 4.55, 11.11) as predictors of OHIP-14. Interaction analysis revealed their associations varied by hospitalisation history. In non-hospitalised individuals, depressive symptoms were positively interacted with OHRQoL (95% CI: 1.34, 9.02). Significant associations were observed between 'experienced, hospitalised' × 'depressive, anxiety and stress symptoms' and OHRQoL in both univariable and multivariable analyses.

Conclusion: A COVID-19 infection history and psychological distress significantly affect OHRQoL in Myanmar participants. Moreover, a strong interactive association was observed between hospitalisation during infection and symptoms of psychological distress.

Objective: Sleep bruxism (SB) is associated with alterations in dopamine and serotonin, which are related to increased consumption of added sugar and overuse of screens. The aim of this study was to compare the effect of the interventions 'Food, Fun and Family' (FFF) and Counselling and Education (CE) on the frequency of SB in children.

Methods: A randomised clinical trial was conducted. Forty-eight participants aged between 4 and 8 years, attending the paediatric clinics of Universidad CES (Colombia) and Hospital Elina de la Serna (Argentina) participated in the study. Subjects were randomised into the FFF (experimental) and CE (regular intervention) groups. The frequency of SB was reported with the Children's Sleep Habits Questionnaire (CSHQ), the consumption of added sugar from items with the HBSC-FFQ and the time of use of screens through a diary in baseline (before starting the intervention), at Week 6 and Week 12. Data were analysed with Kruskal-Wallis test followed by Dunn's post hoc, Mann-Whitney test, a linear mixed model and logistic ordinal regression analyses.

Results: The FFF group had a more significant reduction in consumption of added sugar and screen time compared to the CE group (p < 0.05), especially from Week 6 to baseline. Regression analysis showed that reducing TV watching and consumption of added sugar were associated with a decrease in SB frequency, especially in the FFF group (OR < 1, p < 0.05), and the results were consistent across different study environments.

Conclusion: The FFF intervention was more effective in reducing the screen time and sugar consumption and thus decreased the frequency of SB, when compared with the CE intervention.

Trial registration: ClinicalTrials.gov identifier: NCT05310162.

Background: The foramen of Huschke (FH) and the petrotympanic fissure (PTF) are anatomical structures that can influence temporomandibular joint disorders (TMD) by potentially affecting the movement and function of the mandibular condyle.

Objective: This study investigates the relationship between patients with TMD and the presence of FH and PTF to enhance diagnostic and therapeutic approaches.

Methods: This retrospective study analyzed cone beam computed tomography (CBCT) images from 212 patients. Patients were categorised into TMD and control groups based on standardized DC/TMD protocols. An observer, blinded to the patient's clinical status, then analyzed the CBCT images. The CBCT images were evaluated for the presence and characteristics of FH, PTF, and condyle shape and position.

Results: A higher incidence of FH and PTF was observed in patients with TMD than in the control group. FH was present on the right side in 33.3% of patients with TMD and 18% of controls and on the left side in 23.8% of patients with TMD and 10.9% of controls. Open and semi-open FPT statistically differed between the TMD and control groups (p < 0.05). The length of FH in patients with TMD was significantly larger (2.11 ± 0.44 mm) than in the controls (1.67 ± 0.56 mm). The position of the condyle showed a statistically significant difference between the groups (p < 0.05).

Conclusion: FH and PTF subtypes are significantly associated with TMD, underscoring their importance in clinical practice.

Background: There is a physiological association of the neck movements and jaw and tongue movements. However, there are no previous data regarding the performance of the tongue when the neck is under a lack of movement condition.

Objective: To quantify the tongue's maximal strength and mobility under an experimental restriction of cervical mobility.

Methods: This cross-sectional study recruited 33 healthy volunteers. We measured the tongue's mobility and maximal strength reached at the posterior, middle and anterior parts of the tongue; all were performed with and without neck immobilisation. A neck collar was used for the experimental restriction of cervical mobility.

Results: ANOVA revealed no differences in tongue strength between cervical condition (p = 0.84), but differences were found among the three tongue areas' strength (p < 0.001), according to the post hoc results the posterior area of the tongue resulted significantly weaker compared to the anterior (with collar p = 0.006; without collar p = 0.01) and midparts (with collar p = 0.03; without collar p = 0.006). Significant differences were also found in the tongue's range of motion (ROM) between groups for the protraction (p = 0.02). A subclassification of the participants was made according to the greatest strength obtained with (CCI group) or without (WCI group) neck collar, or no difference (NC group). The analysis of variance showed significant changes in tongue strength between groups at the tongue's anterior area (F = 5.28; p = 0.01), middle area (F = 9.83; p < 0.001) and posterior area (F = 4.05; p = 0.02). The post hoc analyses showed strength in the middle area of the tongue changed between neck conditions, obtaining significantly greater results without the neck collar compared with those with the neck collar (p = 0.01; d = 1.10).

Conclusion: The results of this study indicate a trend suggesting that posture induced by experimental cervical fixation may influence tongue strength, with a possible greater effect in the middle area of the tongue compared to the anterior and posterior areas; however, it affects tongue range of motion. These findings suggest that cervical posture could be an important factor to consider in clinical assessments and interventions involving tongue function. Nonetheless, a larger sample size and further studies are needed to draw more definitive conclusions and understand these potential associations.

Background: Anterior disc displacement (ADD) is the most common type of temporomandibular joint (TMJ) internal derangement and may lead to condylar resorption (CR) during the adolescence period, but the specific malocclusion associated with ADD and CR remains unclear.

Objective: This study aimed to investigate the malocclusion associated with TMJ ADD and CR in adolescents.

Methods: This cross-sectional study included a clinical examination of adolescent patients aged 11-19 years. Magnetic resonance imaging (MRI) was used to diagnose both TMJ ADD and CR. Occlusal measurements were obtained and analysed using 3D scanning models.

Results: A total of 242 adolescent patients (53 males and 189 females) underwent TMJ MRI examination and dental occlusion scanning. The prevalence of anterior disc displacement without reduction (ADDwoR) was higher in females than that in males (OR > 1, p < 0.05). Deep overbite and posterior scissor bite were significantly associated with anterior disc displacement with reduction (ADDwR), while Angle Class II malocclusion, anterior open bite and posterior scissor bite were significantly associated with ADDwoR (OR > 1, p < 0.05). Adolescents with excessive overjet and anterior open bite were at a higher risk of CR (OR > 1, p < 0.05), whereas those with deep overbite and individual crossbite had a lower risk of CR (OR < 1, p < 0.05).

Conclusion: Our study offers valuable insights into the association between deep overbite, posterior scissor bite, Angle Class II malocclusion, anterior open bite, excessive overjet and the ADD and CR in adolescents. Orthodontic treatment for adolescent patients should prioritise the health of the TMJ, particularly for these types of malocclusion.

Background: Sedentary work is a potential health risk factor and may exacerbate painful complaints, while physical activity may serve as a preventive factor for the onset and worsening of musculoskeletal disorders. However, there is scarce evidence on how engaging in leisure physical activity may influence the reporting of temporomandibular dysfunction (TMD) symptoms.

Objective: To assess the association between the level of physical activity and TMD symptoms in office workers.

Methods: This is a cross-sectional study, 225 office workers of both sexes, aged over 18 years, participated in the study. The mean age was 33.65 (± 9.31) years, with a predominantly female sample (67.1%). The TMD Pain Screener determined the presence/absence of TMD symptoms, and the Baecke Habitual Physical Activity Questionnaire (BQHPA) determined the level of physical activity as high/moderate/low.

Results: 25.3% of the total sample presented TMD symptoms, of which 19.1% were women. The total BQHPA score showed that 35.5% of the total sample had a high level of physical activity. Regression analysis revealed no association between TMD symptoms and the level of leisure physical activity.

Conclusion: Office workers exhibited a low prevalence of TMD symptoms, and the presence of TMD symptoms was not associated with the level of physical activity.