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A Comprehensive Approach to the Treatment of Dentofacial Deformities 牙面畸形的综合治疗方法
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 DOI: 10.1016/j.joms.2024.09.003
Leonard B. Kaban DMD, MD , Jeffrey C. Posnick DMD, MD
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引用次数: 0
The American Dream in Oral and Maxillofacial Surgery Residency: A Path Less Taken 口腔颌面外科住院医师的美国梦:一条少有人走的路
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 DOI: 10.1016/j.joms.2024.07.019
Sayyed Ourmazd Mohseni DDS , Asal Saeid BS , Thomas Schlieve DDS, MD
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引用次数: 0
Does Mandibular Distraction Osteogenesis for Robin Sequence Create Altered Craniofacial Morphology and Disrupt Tooth Development? 罗宾序列下颌骨牵引成骨术是否会改变颅面形态并破坏牙齿发育?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 DOI: 10.1016/j.joms.2024.08.001
Geoffrey M. Greenlee DDS, MSD, MPH , Emily Willett DMD, MSD , Srinivas Susarla DDS, MD, MPH , Kelly N. Evans MD , Lloyd Mancl PhD , Barbara Sheller DDS, MSD

Background

Robin Sequence (RS) infant patients may require mandibular distraction osteogenesis (MDO) to improve airway. The distracted mandible may grow vertically and the developing dentition may be disrupted.

Purpose

The study purpose was to measure the association of MDO on craniofacial morphology and tooth development in RS subjects.

Study Design, Setting, Sample

This was a retrospective cohort study of RS infants treated with or without MDO. Inclusion criteria were RS diagnosis, complete imaging, and treatment at our pediatric regional hospital. Exclusion criteria were treatment elsewhere and insufficient imaging.

Exposure Variable

Exposure was airway management; subjects were grouped by use of MDO or not. Subjects were compared to age-matched normal infants presurgically and to age-matched normal controls at follow-up.

Main Outcome Variables

Main outcome variables were craniofacial morphology measured using cephalometric gonial angle and ramus height to mandibular body length ratio presurgically (T1), postsurgically (T2), and at the mixed dentition (T3). Disrupted tooth development was assessed by absence/abnormality of teeth on radiographs at T3.

Covariates

Covariates were age, sex, body mass index, comorbidities, and cephalometric measurements.

Analyses

Appropriate univariate, bivariate, and regression models were computed, and significance level was set at P < .05.

Results

The sample contained 14 RS-MDO subjects with median age of 1.1 months and 10 (71.4%) were female. Presurgery, RS-MDO subjects had significantly more obtuse gonial angles (145° vs 137°, P = .04) and shorter mandibular bodies (32 vs 41 mm, P < .01) than the 37 unaffected controls. Increased ramus height (P < .01) and mandibular body length (P < .01) and forward rotation of the mandible were seen in 12 subjects with post-MDO imaging compared to their presurgical condition.
At mixed dentition, 12 post-MDO subjects had more obtuse gonial angles (P < .01) and steeper mandibular planes (P < .01) than 19 non-MDO RS subjects. Both RS groups had different cephalometric values and more vertical measures than matched cephalometric norms.
Thirty-one percent of 12 RS-MDO subjects had ≥1 teeth with abnormal development compared to none of 19 RS subjects without MDO (P = .02).

Conclusion and Relevance

MDO increased mandibular size in infants but can disrupt the developing dentition. Postdistraction growth may result in more vertical mandibular morphology with large gonial angles.
背景:罗宾序列(RS)婴儿患者可能需要下颌骨牵引成骨术(MDO)来改善气道。研究目的:本研究旨在测量MDO对RS受试者颅面形态和牙齿发育的影响:这是一项回顾性队列研究,研究对象为接受/未接受MDO治疗的RS婴儿。纳入标准为 RS 诊断、完整的影像学检查和在本地区儿科医院接受治疗。排除标准为在其他地方接受治疗且影像学检查不充分:暴露变量:暴露变量为气道管理;受试者按是否使用 MDO 进行分组。受试者在手术前与年龄匹配的正常婴儿进行比较,在随访时与年龄匹配的正常对照组进行比较:主要结果变量是头面部形态,使用头面部测量法测量手术前(T1)、手术后(T2)和混合牙时(T3)的颌角和颌骨高度与下颌骨体长之比。在 T3 阶段,牙齿发育中断的评估标准是射线照片上牙齿的缺失/异常:协变量包括年龄、性别、体重指数、合并症和头颅测量:分析:计算适当的单变量、双变量和回归模型,显著性水平设定为 P 结果:样本中有 14 名 RS-MDO 受试者,中位年龄为 1.1 个月,其中 10 名(71.4%)为女性。手术前,RS-MDO 受试者的盂角明显更钝(145° vs 137°,P = .04),下颌骨体更短(32 mm vs 41 mm,P 结论及相关性:MDO 增加了婴儿的下颌骨大小,但会破坏正在发育的牙列。牵引后的生长可能导致下颌骨形态更垂直,盂角更大。
{"title":"Does Mandibular Distraction Osteogenesis for Robin Sequence Create Altered Craniofacial Morphology and Disrupt Tooth Development?","authors":"Geoffrey M. Greenlee DDS, MSD, MPH ,&nbsp;Emily Willett DMD, MSD ,&nbsp;Srinivas Susarla DDS, MD, MPH ,&nbsp;Kelly N. Evans MD ,&nbsp;Lloyd Mancl PhD ,&nbsp;Barbara Sheller DDS, MSD","doi":"10.1016/j.joms.2024.08.001","DOIUrl":"10.1016/j.joms.2024.08.001","url":null,"abstract":"<div><h3>Background</h3><div>Robin Sequence (RS) infant patients may require mandibular distraction osteogenesis (MDO) to improve airway. The distracted mandible may grow vertically and the developing dentition may be disrupted.</div></div><div><h3>Purpose</h3><div>The study purpose was to measure the association of MDO on craniofacial morphology and tooth development in RS subjects.</div></div><div><h3>Study Design, Setting, Sample</h3><div>This was a retrospective cohort study of RS infants treated with or without MDO. Inclusion criteria were RS diagnosis, complete imaging, and treatment at our pediatric regional hospital. Exclusion criteria were treatment elsewhere and insufficient imaging.</div></div><div><h3>Exposure Variable</h3><div>Exposure was airway management; subjects were grouped by use of MDO or not. Subjects were compared to age-matched normal infants presurgically and to age-matched normal controls at follow-up.</div></div><div><h3>Main Outcome Variables</h3><div>Main outcome variables were craniofacial morphology measured using cephalometric gonial angle and ramus height to mandibular body length ratio presurgically (T1), postsurgically (T2), and at the mixed dentition (T3). Disrupted tooth development was assessed by absence/abnormality of teeth on radiographs at T3.</div></div><div><h3>Covariates</h3><div>Covariates were age, sex, body mass index, comorbidities, and cephalometric measurements.</div></div><div><h3>Analyses</h3><div>Appropriate univariate, bivariate, and regression models were computed, and significance level was set at <em>P</em> &lt; .05.</div></div><div><h3>Results</h3><div>The sample contained 14 RS-MDO subjects with median age of 1.1 months and 10 (71.4%) were female. Presurgery, RS-MDO subjects had significantly more obtuse gonial angles (145° vs 137°, <em>P</em> = .04) and shorter mandibular bodies (32 vs 41 mm, <em>P</em> &lt; .01) than the 37 unaffected controls. Increased ramus height (<em>P</em> &lt; .01) and mandibular body length (<em>P</em> &lt; .01) and forward rotation of the mandible were seen in 12 subjects with post-MDO imaging compared to their presurgical condition.</div><div>At mixed dentition, 12 post-MDO subjects had more obtuse gonial angles (<em>P</em> &lt; .01) and steeper mandibular planes (<em>P</em> &lt; .01) than 19 non-MDO RS subjects. Both RS groups had different cephalometric values and more vertical measures than matched cephalometric norms.</div><div>Thirty-one percent of 12 RS-MDO subjects had ≥1 teeth with abnormal development compared to none of 19 RS subjects without MDO (<em>P</em> = .02).</div></div><div><h3>Conclusion and Relevance</h3><div>MDO increased mandibular size in infants but can disrupt the developing dentition. Postdistraction growth may result in more vertical mandibular morphology with large gonial angles.</div></div>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":"82 12","pages":"Pages 1549-1558"},"PeriodicalIF":2.3,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142055877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zoledronic Acid-Treated Rats Show Altered Jaw Histology and Gene Expression in Nonexposed Medication-Related Osteonecrosis of the Jaws 唑来膦酸处理的大鼠在未接触药物导致的颌骨骨坏死中表现出颌骨组织学和基因表达的改变
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-12-01 DOI: 10.1016/j.joms.2024.08.067
Lijun Sun MDS , Rui Dong MDS , Shihan Zhang MDS , Jiaqi Zhu MDS , Lingjie Zheng MDS , Jian Zhang DDS, PhD

Background

Diagnosis and management of medication-related osteonecrosis of the jaws (MRONJ) prior to clinical exposure induced by trauma may lead to improved patient management. Currently, few studies have examined early histologic and molecular MRONJ-related changes in the jaws.

Purpose

This study aimed to identify histological and gene expression changes in the maxilla and mandible of Sprague-Dawley (SD) rats after zoledronic acid (ZA) treatment.

Study Design, Setting, and Sample

This was an in vivo animal study. The experiments were conducted in the laboratory at the Stomatology Hospital of Tianjin Medical University. A total of 12 SD rats were included.

Predictor Variable

The predictor variable was ZA exposure. Twelve SD rats were divided into 2 groups: experimental (n = 6) and control (n = 6), and they were intraperitoneally injected with ZA and saline, respectively.

Main Outcome Variable

The outcome variables were histological and molecular changes. The maxilla, mandible, and ilium bone tissue samples were examined using Masson's trichrome and hematoxylin-eosin staining. Gene expression changes were identified using transcriptome sequencing, the Kyoto encyclopedia of genes and genomes, and gene interactome network analysis. The key changes were validated using the quantitative real-time polymerase chain reaction and immunohistochemistry.

Covariates

None.

Analyses

The t-test, χ2 test, and Fisher's exact probability method were used for statistical analyses using the Statistical Package for the Social Sciences software (version 26.0).

Results

All animals remained healthy during the experiments. Histological staining revealed that the percentage of empty bone lacunae in the maxilla and mandible was significantly higher than that in the ilium (P < .01). In total, 552 genes were screened using transcriptome sequencing. The sonic hedgehog (Shh) signaling pathway was highly enriched. The key gene for the Shh interaction was distal-less homeobox 5. The Shh, distal-less homeobox 5, and bone morphogenetic protein 2 genes and protein expression levels in the maxilla and mandible were higher in the experimental group than in the control group (P < .05).

Conclusion and Relevance

MRONJ-induced osteonecrosis and gene expression changes precede trauma-induced clinical changes in the SD rat model. These findings may provide additional support for timely and clinically early diagnosis and intervention.
背景:在创伤引起的临床暴露之前诊断和处理与药物相关的颌骨骨坏死(MRONJ)可能会改善对患者的管理。目的:本研究旨在确定唑来膦酸(ZA)治疗后Sprague-Dawley(SD)大鼠上颌骨和下颌骨的组织学和基因表达变化:这是一项体内动物研究。实验在天津医科大学口腔医院实验室进行。共纳入 12 只 SD 大鼠:预测变量:ZA 暴露。12只SD大鼠分为两组:实验组(n = 6)和对照组(n = 6),分别腹腔注射ZA和生理盐水:主要结果变量:结果变量为组织学和分子变化。采用马森三色染色法和苏木精-伊红染色法检查上颌骨、下颌骨和髂骨组织样本。通过转录组测序、京都基因和基因组百科全书以及基因相互作用组网络分析,确定了基因表达的变化。关键变化通过实时定量聚合酶链反应和免疫组化进行验证:分析统计分析采用 t 检验、χ2 检验和费雪精确概率法,使用社会科学统计软件包(26.0 版):所有动物在实验期间均保持健康。组织学染色显示,上颌骨和下颌骨空骨裂的百分比明显高于髂骨(P 结论和相关性):在 SD 大鼠模型中,MRONJ 诱导的骨坏死和基因表达变化先于创伤诱导的临床变化。这些发现可为及时和临床早期诊断和干预提供更多支持。
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引用次数: 0
Patterns of Orbital Fractures Caused by Sports Injuries in Children. 儿童运动损伤所致眼眶骨折的类型。
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-30 DOI: 10.1016/j.joms.2024.11.011
Joyce Xu, Shelly Abramowicz

Background: Sports injuries account for 11.3 to 42.1% of the facial fractures. Injuries from contact with a ball, a bat or stick, or another player raise safety concerns.

Purpose: The purpose of this study was to assess the patterns of sports-related maxillofacial injuries involving orbital bone fractures in children.

Study design, setting, and sample: This was a retrospective case series of children who presented to Children's Healthcare of Atlanta from 2015 to 2021, with orbital injuries resulting from sports.

Independent variable: None.

Outcome variable: The outcome variables, including the fracture location, pattern, and the management of injury.

Covariates: The medical record were reviewed for the following variables: 1) demographic information, 2) mechanism of injury, 3) type of sport, 4) symptoms, 5) length of inpatient stay, and 6) duration of follow-up.

Analysis: Data were collected using a standardized collection form. Descriptive statistics were calculated.

Results: Overall, 101 patients (92 males) with an age of 13 ± 3 met the inclusion criteria. The most common sport was baseball or softball (n = 78, 77.2%). The mechanisms of injuries were largely due to collision with the ball (n = 79, 78.2%) or with another player (n = 13, 12.9%). Orbital fractures occurred mostly in the floor (n = 87, 86.1%), followed by the medial wall (n = 22, 21.8%), with an average of 1 surface involved. Maxillary sinus (n = 23, 22.8%) and/or nasal bone (n = 17, 16.8%) were the other facial bones outside of orbit commonly injured. The fractures patterns are minimally/nondisplaced (n = 68, 67.3%), displaced (n = 30, 29.7%), or comminuted (n = 3, 3%). The managements include surgical and nonsurgical. Twenty-three patients (22.8%) underwent surgical intervention. Twelve of them had an emergent operation due to extraocular muscle entrapment.

Conclusion: Sports injuries are a common cause of orbital trauma in children. Most injuries are due to baseball/softball from collision with the ball. They were mostly managed without surgery, except for the individuals that presented with entrapment, oculocardiac reflex, and a large-size defect. The information from this project could be utilized in implementing safety equipment use for participants to further prevent such injuries.

背景:运动损伤占面部骨折的11.3 ~ 42.1%。与球、球棒或球棒或其他球员接触造成的伤害引起了人们对安全的关注。目的:本研究的目的是评估儿童眶骨骨折的运动相关颌面损伤的模式。研究设计、环境和样本:这是一个回顾性的病例系列,研究对象是2015年至2021年在亚特兰大儿童医疗中心就诊的因运动导致眼眶损伤的儿童。自变量:无。结果变量:结果变量,包括骨折位置、模式和损伤处理。协变量:对医疗记录进行以下变量的审查:1)人口统计信息,2)损伤机制,3)运动类型,4)症状,5)住院时间,6)随访时间。分析:使用标准化的收集表格收集数据。进行描述性统计。结果:101例患者(男性92例)符合纳入标准,年龄13±3岁。最常见的运动是棒球或垒球(n = 78, 77.2%)。损伤机制主要是与球碰撞(n = 79, 78.2%)或与其他球员碰撞(n = 13, 12.9%)。眼眶骨折多发生于眶底(n = 87, 86.1%),其次为眶内侧壁(n = 22, 21.8%),平均1个面受累。上颌窦(n = 23, 22.8%)和/或鼻骨(n = 17, 16.8%)是眼眶外常见的面骨。骨折类型为轻度/非移位(n = 68, 67.3%)、移位(n = 30, 29.7%)和粉碎性(n = 3.3, 3%)。治疗方法包括手术治疗和非手术治疗。手术干预23例(22.8%)。其中12例因眼外肌夹持而行紧急手术。结论:运动损伤是儿童眼眶外伤的常见原因。大多数伤害是由于棒球/垒球与球的碰撞造成的。除了出现夹持、心房反射和大尺寸缺损的个体外,他们大多不需要手术。该项目提供的信息可用于实施安全设备的使用,以进一步防止此类伤害。
{"title":"Patterns of Orbital Fractures Caused by Sports Injuries in Children.","authors":"Joyce Xu, Shelly Abramowicz","doi":"10.1016/j.joms.2024.11.011","DOIUrl":"10.1016/j.joms.2024.11.011","url":null,"abstract":"<p><strong>Background: </strong>Sports injuries account for 11.3 to 42.1% of the facial fractures. Injuries from contact with a ball, a bat or stick, or another player raise safety concerns.</p><p><strong>Purpose: </strong>The purpose of this study was to assess the patterns of sports-related maxillofacial injuries involving orbital bone fractures in children.</p><p><strong>Study design, setting, and sample: </strong>This was a retrospective case series of children who presented to Children's Healthcare of Atlanta from 2015 to 2021, with orbital injuries resulting from sports.</p><p><strong>Independent variable: </strong>None.</p><p><strong>Outcome variable: </strong>The outcome variables, including the fracture location, pattern, and the management of injury.</p><p><strong>Covariates: </strong>The medical record were reviewed for the following variables: 1) demographic information, 2) mechanism of injury, 3) type of sport, 4) symptoms, 5) length of inpatient stay, and 6) duration of follow-up.</p><p><strong>Analysis: </strong>Data were collected using a standardized collection form. Descriptive statistics were calculated.</p><p><strong>Results: </strong>Overall, 101 patients (92 males) with an age of 13 ± 3 met the inclusion criteria. The most common sport was baseball or softball (n = 78, 77.2%). The mechanisms of injuries were largely due to collision with the ball (n = 79, 78.2%) or with another player (n = 13, 12.9%). Orbital fractures occurred mostly in the floor (n = 87, 86.1%), followed by the medial wall (n = 22, 21.8%), with an average of 1 surface involved. Maxillary sinus (n = 23, 22.8%) and/or nasal bone (n = 17, 16.8%) were the other facial bones outside of orbit commonly injured. The fractures patterns are minimally/nondisplaced (n = 68, 67.3%), displaced (n = 30, 29.7%), or comminuted (n = 3, 3%). The managements include surgical and nonsurgical. Twenty-three patients (22.8%) underwent surgical intervention. Twelve of them had an emergent operation due to extraocular muscle entrapment.</p><p><strong>Conclusion: </strong>Sports injuries are a common cause of orbital trauma in children. Most injuries are due to baseball/softball from collision with the ball. They were mostly managed without surgery, except for the individuals that presented with entrapment, oculocardiac reflex, and a large-size defect. The information from this project could be utilized in implementing safety equipment use for participants to further prevent such injuries.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is Postoperative Nausea and Vomiting Associated With Increased Postoperative Pain in Patients Undergoing Minor Oral and Maxillofacial Surgery Under General Anesthesia? 在全身麻醉下接受口腔小手术的患者,术后恶心和呕吐是否与术后疼痛加剧有关?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-30 DOI: 10.1016/j.joms.2024.11.012
Tina Nakamura, Fumika Ogata, Hiroshi Hoshijima, Hiroshi Nagasaka, Katsushi Doi, Tsutomu Mieda

Background: Whether postoperative nausea and vomiting (PONV) contributes to increased postoperative pain (POP) remains unclear, although POP is reported to cause PONV.

Purpose: This study aimed to determine whether PONV following minor oral and maxillofacial surgery (OMS) under general anesthesia increases POP.

Study design, setting, sample: The researchers implemented a retrospective cohort study. Patients who presented to Saitama Medical University Hospital between January 2021 and August 2022 and who required minor OMS under general anesthesia were identified from a review of electronic records. The inclusion criteria were patients aged between 16 and 65 years and nasal intubation via inhalational or propofol-based total intravenous general anesthesia. The exclusion criterion was patients who had diseases affecting POP or PONV.

Predictor variables: The primary predictor variable was the occurrence of PONV (yes/no) at 2 hours postoperatively.

Main outcome variables: The main outcome variable was POP measured on a 100 mm visual analog scale (VAS) at 2 hours postoperatively. The secondary outcome was the timing of POP, which was measured at 6 hours.

Covariates: Covariates included patient-related factors (age, body mass index, American Society of Anesthesiologists Physical Status, smoking status, and history of PONV or motion sickness), anesthesia-related factors (intraoperative analgesics, intraoperative antiemetics, duration of anesthesia, and anesthesia type), and surgery-related factors (surgery type and duration of surgery).

Analyses: Analyses were used for ordinal, categorical, and continuous variables. The POP VAS values were compared between each measurement time with repeated-measures analysis of variance. A P value < .05 indicated statistical significance.

Results: The sample included 148 patients with a mean age of 40 ± 16.5 years, 66 (44.6%) of whom were male. The incidence of PONV was 31 (20.9%) at 0 to 2 hours, 7 (4.7%) at 2 to 6 hours, and 0 (0%) at 6 to 24 hours. POP VAS scores were significantly higher in the PONV group than in the non-PONV group at 2 hours. The mean VAS score at 2 hours was 40.5 ± 29.2 (PONV group) versus 29.8 ± 23.7 (non-PONV group) (P = .03); the VAS score at 6 hours was 41.0 ± 29.4 (PONV group) compared with 25.4 ± 26.4 (non-PONV group) (P = .13).

Conclusion: Our present study revealed that PONV is associated with increased POP in patients undergoing minor OMS under general anesthesia.

背景:术后恶心和呕吐(PONV)是否导致术后疼痛(POP)增加尚不清楚,尽管有报道称POP会导致PONV。目的:本研究旨在确定全身麻醉下小口腔手术(MOS)后PONV是否会增加POP。研究设计、环境、样本:研究人员采用回顾性队列研究。在2021年1月至2022年8月期间到埼玉医科大学医院就诊并在全身麻醉下需要MOS的患者通过对电子记录的审查确定。纳入标准为年龄在16 - 65岁之间的患者,通过吸入或以异丙酚为基础的全静脉全身麻醉进行鼻插管。排除标准为有影响POP或PONV疾病的患者。预测变量:主要预测变量为术后2小时PONV的发生(是/否)。主要结果变量:主要结果变量为术后2小时100 mm视觉模拟量表(VAS)测得的POP。次要结果是POP的时间,在6小时测量。协变量:协变量包括患者相关因素(年龄、体重指数、美国麻醉医师协会身体状况、吸烟状况、PONV或晕动病病史)、麻醉相关因素(术中镇痛药、术中止吐药、麻醉持续时间、麻醉类型)和手术相关因素(手术类型和手术持续时间)。分析:对顺序变量、分类变量和连续变量进行分析。采用重复测量方差分析比较各测量时间间的POP VAS值。P值< 0.05为有统计学意义。结果:148例患者,平均年龄40±16.5岁,其中男性66例(44.6%)。0 ~ 2小时PONV发生率为31例(20.9%),2 ~ 6小时发生率为7例(4.7%),6 ~ 24小时发生率为0例(0%)。2小时时,PONV组的POP VAS评分明显高于非PONV组。2小时VAS评分(PONV组)为40.5±29.2分,非PONV组为29.8±23.7分(P = 0.03);6 h VAS评分:PONV组(41.0±29.4),非PONV组(25.4±26.4),差异有统计学意义(P = 0.13)。结论:我们目前的研究表明,在全麻下接受MOS的患者中,PONV与POP增加有关。
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引用次数: 0
Does Social Media Increase Perioperative Anxiety in Patients Undergoing Impacted Third Molar Surgery? 社交媒体会增加第三磨牙手术患者围手术期焦虑吗?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-22 DOI: 10.1016/j.joms.2024.11.010
Ufuk Tatli, Tahayasin Kalkan

Background: In anticipation of third molar surgery, patients may experience increased anxiety. Patients frequently access social media platforms and view content about surgical treatments.

Purpose: The study purpose was to measure the level of perioperative anxiety of patients scheduled for third molar surgery exposed to social media and identify factors associated with patient anxiety.

Study design, setting, sample: This is a prospective cohort study of patients undergoing impacted mandibular third molar surgery from September 2021 to August 2022 at the outpatient clinic of Cukurova University School of Dentistry.

Predictor variable: The predictor variable was level of exposure to viewing third molar surgery-related social media before the surgery. Subjects were divided into 2 groups based on social media viewing preferences at their own discretion: the control group involved patients who did not view social media and study group involved patients who viewed social media before the surgery.

Main outcome variables: The outcome variables were patients' anxiety levels assessed using Modified Dental Anxiety Scale and Spielberger State Anxiety Inventory.

Covariates: Covariates were age, sex, education level, history of previous dentist visit, and impacted third molar surgery.

Analyses: Student t-test, Mann-Whitney U test, χ2 test, Kruskal-Wallis test, one-way analysis of variance, and post hoc tests were used according to data. Level of significance was set at P < .05.

Results: The study sample comprised 162 patients; 82 (50.6%) patients were in the control group and 80 (49.4%) were in the social media group. The Modified Dental Anxiety Scale scores of the social media group (11.95 ± 4.50) were statistically higher than the control group (9.66 ± 4.28) (P = .001). The Spielberger State Anxiety Inventory scores of the social media group (46.43 ± 5.80) were statistically higher than the control group (44.52 ± 5.53) (P = .03). There were statistical differences in anxiety levels considering some covariates. In social media group, there were some statistical differences in anxiety levels of patients who viewed different social media type and content.

Conclusion and relevance: Patients who viewed social media on their own preferences before the surgery had higher perioperative anxiety compared to those who did not. The effects of demographic variables, different social media types and content on perioperative anxiety should be taken into account during stress management of the patients.

背景:在第三磨牙手术的预期中,患者可能会感到焦虑增加。患者经常访问社交媒体平台,查看有关手术治疗的内容。目的:研究目的是测量第三磨牙手术患者暴露于社交媒体的围手术期焦虑水平,并确定与患者焦虑相关的因素。研究设计、环境、样本:这是一项前瞻性队列研究,研究对象是2021年9月至2022年8月在库库罗娃大学牙科学院门诊接受下颌第三磨牙阻生手术的患者。预测变量:预测变量是在手术前观看第三磨牙手术相关社交媒体的水平。受试者根据自己的社交媒体浏览偏好分为两组:对照组患者不浏览社交媒体,研究组患者在手术前浏览社交媒体。主要结果变量:结果变量为患者的焦虑水平,采用改良牙科焦虑量表和Spielberger状态焦虑量表评估。协变量:年龄、性别、受教育程度、既往牙医就诊史、影响第三磨牙手术。分析:根据资料采用学生t检验、Mann-Whitney U检验、χ2检验、Kruskal-Wallis检验、单因素方差分析和事后检验。结果:研究样本包括162例患者;对照组82例(50.6%),社交媒体组80例(49.4%)。社交媒体组患者改良牙科焦虑量表得分(11.95±4.50)分高于对照组(9.66±4.28)分(P = .001)。社交媒体组患者斯皮尔伯格状态焦虑量表得分(46.43±5.80)高于对照组(44.52±5.53),差异有统计学意义(P = .03)。考虑到一些协变量,焦虑水平存在统计学差异。在社交媒体组中,浏览不同社交媒体类型和内容的患者焦虑水平存在统计学差异。结论和相关性:在手术前根据自己的喜好浏览社交媒体的患者比不这样做的患者有更高的围手术期焦虑。在患者压力管理中应考虑人口统计学变量、不同社交媒体类型和内容对围手术期焦虑的影响。
{"title":"Does Social Media Increase Perioperative Anxiety in Patients Undergoing Impacted Third Molar Surgery?","authors":"Ufuk Tatli, Tahayasin Kalkan","doi":"10.1016/j.joms.2024.11.010","DOIUrl":"10.1016/j.joms.2024.11.010","url":null,"abstract":"<p><strong>Background: </strong>In anticipation of third molar surgery, patients may experience increased anxiety. Patients frequently access social media platforms and view content about surgical treatments.</p><p><strong>Purpose: </strong>The study purpose was to measure the level of perioperative anxiety of patients scheduled for third molar surgery exposed to social media and identify factors associated with patient anxiety.</p><p><strong>Study design, setting, sample: </strong>This is a prospective cohort study of patients undergoing impacted mandibular third molar surgery from September 2021 to August 2022 at the outpatient clinic of Cukurova University School of Dentistry.</p><p><strong>Predictor variable: </strong>The predictor variable was level of exposure to viewing third molar surgery-related social media before the surgery. Subjects were divided into 2 groups based on social media viewing preferences at their own discretion: the control group involved patients who did not view social media and study group involved patients who viewed social media before the surgery.</p><p><strong>Main outcome variables: </strong>The outcome variables were patients' anxiety levels assessed using Modified Dental Anxiety Scale and Spielberger State Anxiety Inventory.</p><p><strong>Covariates: </strong>Covariates were age, sex, education level, history of previous dentist visit, and impacted third molar surgery.</p><p><strong>Analyses: </strong>Student t-test, Mann-Whitney U test, χ<sup>2</sup> test, Kruskal-Wallis test, one-way analysis of variance, and post hoc tests were used according to data. Level of significance was set at P < .05.</p><p><strong>Results: </strong>The study sample comprised 162 patients; 82 (50.6%) patients were in the control group and 80 (49.4%) were in the social media group. The Modified Dental Anxiety Scale scores of the social media group (11.95 ± 4.50) were statistically higher than the control group (9.66 ± 4.28) (P = .001). The Spielberger State Anxiety Inventory scores of the social media group (46.43 ± 5.80) were statistically higher than the control group (44.52 ± 5.53) (P = .03). There were statistical differences in anxiety levels considering some covariates. In social media group, there were some statistical differences in anxiety levels of patients who viewed different social media type and content.</p><p><strong>Conclusion and relevance: </strong>Patients who viewed social media on their own preferences before the surgery had higher perioperative anxiety compared to those who did not. The effects of demographic variables, different social media types and content on perioperative anxiety should be taken into account during stress management of the patients.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photobiomodulation With Infrared and Dual-Wavelength Laser Induces Similar Repair and Control of Inflammation After Third Molar Extraction: A Double-Blinded Split-Mouth Randomized Controlled Trial. 红外和双波长激光的光生物调节诱导第三磨牙拔除后类似的修复和炎症控制:双盲裂口随机对照试验。
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-20 DOI: 10.1016/j.joms.2024.11.009
Davisson Alves Pereira, Mariana Silva Bonatto, Eduvaldo Campos Soares, Pedro Gomes Junqueira Mendes, Roberto Sales E Pessoa, Guilherme José Pimentel Lopes de Oliveira

Background: Photobiomodulation therapy (PBMT) has been showed to have beneficial effects on the healing and control of inflammation associated with oral surgical wounds. However, different PBMT protocols have been proposed and it is not clear if different protocols impact the hard and soft tissues healing equally.

Purpose: To compare the tissue repair of postextraction alveoli of third molars between treated with dual-wavelength PBMT (red and infrared) or PBMT with infrared laser (IRL) alone.

Study design, setting, sample: This split mouth randomized controlled trial enrolled 20 patients, who were submitted to the extraction of the 4 partially erupted or fully impacted third molars between August 2023 and December 2023 at the clinic of the INPES postgraduate school (Institute for Clinical Health Research), and at the Federal University of Uberlândia. Adult with all the 4 molars were included in this study, while patients with systemic diseases/conditions, with less than 4 third molars were excluded of this study.

Exposure variable: The exposure variable is PBMT treatment. Treatment side was randomly allocated to according to the PBMT protocol applied on the postextraction sockets: IRL-PBMT: irradiation with PBMT with an IRL (808 nm) and IRL-RL-PBMT: irradiation with dual-wavelength PBMT (660 and 808 nm).

Main outcome variable(s): The primary outcome variable was the bone tissue healing that was measured using the fractal analysis and bone tissue density assessed using the radiographic images. The secondary outcome variable was soft tissue healing measured assessing the facial dimensions variations and a healing index that assessed the tissue consistence, color, exudation, bleeding, and edema. Additionally, the analyses centered on the patients' perceptions was assessed by the application of a visual analogic scale to assess pain, bleeding, edema, difficulty in chewing, and mouth opening conditions. Subjects were clinically evaluated at 3, 7, 14, 30, and 90 days after the surgical procedure.

Covariates: The covariates are the tooth position, and the demographic data (age and sex).

Analyses: The evaluation of the effects of the independent variables (Treatment and period of evaluation) on the primary and secondary outcomes was performed through the application of the repeated measures ANOVA (P < .05).

Results: The sample was composed of 20 subjects with a mean age of 28.58 ± 8.94 years, and 12 (60%) were females. There were no statistically significant differences between the 2 treatments for any outcome variables (P > .10).

Conclusion and relevance: It can be concluded that PBMT with dual wavelengths (red and infrared) and an IRL alone induced similar postoperative clinical results after third molar extraction surgeries.

背景:光生物调节疗法(PBMT)已被证明对口腔外科伤口相关炎症的愈合和控制有有益的作用。然而,不同的PBMT方案已经被提出,并且不清楚不同的方案对硬组织和软组织愈合的影响是否相同。目的:比较双波长PBMT(红色和红外线)与单独使用红外激光(IRL)治疗第三磨牙拔牙后牙槽的组织修复效果。研究设计、环境、样本:这项裂口随机对照试验招募了20名患者,他们于2023年8月至2023年12月在INPES研究生院(临床健康研究所)和印度uberl联邦大学的诊所接受了4颗部分萌出或完全阻生的第三磨牙的拔除。所有4颗磨牙的成年人被纳入本研究,而患有全身性疾病/病症的患者,少于4颗三分之一磨牙被排除在本研究之外。暴露变量:暴露变量是PBMT治疗。根据拔牙后插槽上应用的PBMT方案,随机分配治疗侧:IRL-PBMT:用IRL PBMT照射(808 nm), IRL- rl -PBMT:双波长PBMT照射(660和808 nm)。主要结局变量:主要结局变量为骨组织愈合,使用分形分析测量骨组织愈合,使用x线图像评估骨组织密度。次要结果变量是评估面部尺寸变化的软组织愈合测量和评估组织一致性、颜色、渗出、出血和水肿的愈合指数。此外,通过应用视觉类比量表评估患者的感知,以评估疼痛、出血、水肿、咀嚼困难和张嘴状况。在手术后3、7、14、30和90天对受试者进行临床评估。协变量:协变量是牙齿位置和人口统计数据(年龄和性别)。分析:采用重复测量方差分析(P)评价自变量(治疗方法和评价期)对主要和次要结局的影响。结果:样本由20名受试者组成,平均年龄28.58±8.94岁,其中12名(60%)为女性。两种治疗在任何结局变量上均无统计学差异(P < 0.05)。结论及相关性:在第三磨牙拔牙术后,双波长(红光和红外线)PBMT与单独使用IRL的临床效果相似。
{"title":"Photobiomodulation With Infrared and Dual-Wavelength Laser Induces Similar Repair and Control of Inflammation After Third Molar Extraction: A Double-Blinded Split-Mouth Randomized Controlled Trial.","authors":"Davisson Alves Pereira, Mariana Silva Bonatto, Eduvaldo Campos Soares, Pedro Gomes Junqueira Mendes, Roberto Sales E Pessoa, Guilherme José Pimentel Lopes de Oliveira","doi":"10.1016/j.joms.2024.11.009","DOIUrl":"10.1016/j.joms.2024.11.009","url":null,"abstract":"<p><strong>Background: </strong>Photobiomodulation therapy (PBMT) has been showed to have beneficial effects on the healing and control of inflammation associated with oral surgical wounds. However, different PBMT protocols have been proposed and it is not clear if different protocols impact the hard and soft tissues healing equally.</p><p><strong>Purpose: </strong>To compare the tissue repair of postextraction alveoli of third molars between treated with dual-wavelength PBMT (red and infrared) or PBMT with infrared laser (IRL) alone.</p><p><strong>Study design, setting, sample: </strong>This split mouth randomized controlled trial enrolled 20 patients, who were submitted to the extraction of the 4 partially erupted or fully impacted third molars between August 2023 and December 2023 at the clinic of the INPES postgraduate school (Institute for Clinical Health Research), and at the Federal University of Uberlândia. Adult with all the 4 molars were included in this study, while patients with systemic diseases/conditions, with less than 4 third molars were excluded of this study.</p><p><strong>Exposure variable: </strong>The exposure variable is PBMT treatment. Treatment side was randomly allocated to according to the PBMT protocol applied on the postextraction sockets: IRL-PBMT: irradiation with PBMT with an IRL (808 nm) and IRL-RL-PBMT: irradiation with dual-wavelength PBMT (660 and 808 nm).</p><p><strong>Main outcome variable(s): </strong>The primary outcome variable was the bone tissue healing that was measured using the fractal analysis and bone tissue density assessed using the radiographic images. The secondary outcome variable was soft tissue healing measured assessing the facial dimensions variations and a healing index that assessed the tissue consistence, color, exudation, bleeding, and edema. Additionally, the analyses centered on the patients' perceptions was assessed by the application of a visual analogic scale to assess pain, bleeding, edema, difficulty in chewing, and mouth opening conditions. Subjects were clinically evaluated at 3, 7, 14, 30, and 90 days after the surgical procedure.</p><p><strong>Covariates: </strong>The covariates are the tooth position, and the demographic data (age and sex).</p><p><strong>Analyses: </strong>The evaluation of the effects of the independent variables (Treatment and period of evaluation) on the primary and secondary outcomes was performed through the application of the repeated measures ANOVA (P < .05).</p><p><strong>Results: </strong>The sample was composed of 20 subjects with a mean age of 28.58 ± 8.94 years, and 12 (60%) were females. There were no statistically significant differences between the 2 treatments for any outcome variables (P > .10).</p><p><strong>Conclusion and relevance: </strong>It can be concluded that PBMT with dual wavelengths (red and infrared) and an IRL alone induced similar postoperative clinical results after third molar extraction surgeries.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is the Complexity of Arthroscopic Temporomandibular Joint Surgery Associated With Short-Term Complication Rates? 关节镜下颞下颌关节手术的复杂性与短期并发症发生率有关吗?
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-20 DOI: 10.1016/j.joms.2024.11.008
Daniel Jerez-Frederick, Daniela Albers, Carlos Fuenzalida, German Laissle, Camila Ávila-Oliver

Background: Arthroscopy is regarded as a minimally invasive surgical procedure, with complication rates ranging from 1.7 to 4.4%. It remains unclear whether the complexity of the arthroscopic procedure is associated with the frequency of complications.

Purpose: The study purpose was to measure the association between the level of arthroscopic complexity and short-term postoperative complications.

Study design, setting, sample: The researchers implemented a prospective cohort study. Subjects presenting to Clinica Bupa Santiago, a tertiary care hospital in Chile between 2022 and 2023 who requires arthroscopy were enrolled. Inclusion criteria required subjects to have a history of joint disorder and a preoperative magnetic resonance imaging (MRI) to be scheduled for an arthroscopic surgery with a 6-month follow-up. Subjects lacking 6-month follow-up were excluded.

Predictor variable: The predictor variable was the arthroscopy complexity level: level I (single puncture diagnostic sweep), level II (double puncture with instrumentation or shaver), and level III (discopexy or discectomy).

Main outcome variable: The main outcome variable was intraoperative and postoperative complications, which were defined as any unwanted development resulting in lasting consequences, additional surgeries, or unresolved issues, and these were coded as either present or absent.

Covariates: The covariates included age, sex, duration of symptoms, prior conservative therapies, history of previous open joint surgery, and Wilkes stage.

Analyses: Data were analyzed using descriptive statistics with statistical significance set at P value <.05. χ2 or Fisher's exact test was used depending on the variable type.

Results: A total of 165 subjects (285 joints) with a mean age of 28.9 years (SD 13.0) were included. Of these, 149 (90.3%) were female and 16 (9.7%) were male. Level I procedures were performed on 37 joints (13.0%) in 23 subjects (16.3%), level II on 53 joints (18.6%) in 27 subjects (16.3%), and level III on 195 joints (68.4%) in 116 subjects (69.9%). Complications occurred only in level III (7 procedures, 2.5%, P = .33), affecting 5 subjects (3.0%). Observed complications included transient frontal facial paresis, mouth floor edema, transient neuropathic pain, suture rejection, and emphysema.

Conclusion and relevance: The postoperative complication rate after arthroscopy was 2.5%, with no statistically significant association with operative complexity. Although more complications were observed in advanced arthroscopies, this increase was not significant.

背景:关节镜检查被认为是一种微创手术,其并发症发生率为1.7 - 4.4%。目前尚不清楚关节镜手术的复杂性是否与并发症的发生频率有关。目的:研究目的是测量关节镜复杂性水平与术后短期并发症之间的关系。研究设计、环境、样本:研究人员实施了一项前瞻性队列研究。研究纳入了2022年至2023年间到智利三级护理医院圣地亚哥临床保柏医院就诊并需要关节镜检查的受试者。纳入标准要求受试者有关节疾病史,术前进行磁共振成像并随访6个月进行关节镜手术。缺少6个月随访的受试者被排除在外。预测变量:预测变量为关节镜复杂性水平:I级(单穿刺诊断扫描),II级(器械或刮刀双重穿刺),III级(椎间盘切除术或椎间盘切除术)。主要结局变量:主要结局变量为术中和术后并发症,其定义为任何导致持久后果的不良发展,额外的手术或未解决的问题,这些被编码为存在或不存在。协变量:协变量包括年龄、性别、症状持续时间、既往保守治疗、既往开放关节手术史和Wilkes分期。分析:根据变量类型,采用P值为2的描述性统计或Fisher精确检验对数据进行分析。结果:共纳入165例患者(285个关节),平均年龄28.9岁(SD 13.0)。其中女性149例(90.3%),男性16例(9.7%)。一级手术治疗了23例(16.3%)患者的37个关节(13.0%),二级手术治疗了27例(16.3%)患者的53个关节(18.6%),三级手术治疗了116例(69.9%)患者的195个关节(68.4%)。并发症仅发生在III级(7例,2.5%,P = 0.33),影响5例(3.0%)。观察到的并发症包括短暂性额面轻瘫、口底水肿、短暂性神经性疼痛、缝合排斥反应和肺气肿。结论及意义:关节镜术后并发症发生率为2.5%,与手术复杂性无统计学意义。虽然在晚期关节镜检查中观察到更多的并发症,但这种增加并不显著。
{"title":"Is the Complexity of Arthroscopic Temporomandibular Joint Surgery Associated With Short-Term Complication Rates?","authors":"Daniel Jerez-Frederick, Daniela Albers, Carlos Fuenzalida, German Laissle, Camila Ávila-Oliver","doi":"10.1016/j.joms.2024.11.008","DOIUrl":"10.1016/j.joms.2024.11.008","url":null,"abstract":"<p><strong>Background: </strong>Arthroscopy is regarded as a minimally invasive surgical procedure, with complication rates ranging from 1.7 to 4.4%. It remains unclear whether the complexity of the arthroscopic procedure is associated with the frequency of complications.</p><p><strong>Purpose: </strong>The study purpose was to measure the association between the level of arthroscopic complexity and short-term postoperative complications.</p><p><strong>Study design, setting, sample: </strong>The researchers implemented a prospective cohort study. Subjects presenting to Clinica Bupa Santiago, a tertiary care hospital in Chile between 2022 and 2023 who requires arthroscopy were enrolled. Inclusion criteria required subjects to have a history of joint disorder and a preoperative magnetic resonance imaging (MRI) to be scheduled for an arthroscopic surgery with a 6-month follow-up. Subjects lacking 6-month follow-up were excluded.</p><p><strong>Predictor variable: </strong>The predictor variable was the arthroscopy complexity level: level I (single puncture diagnostic sweep), level II (double puncture with instrumentation or shaver), and level III (discopexy or discectomy).</p><p><strong>Main outcome variable: </strong>The main outcome variable was intraoperative and postoperative complications, which were defined as any unwanted development resulting in lasting consequences, additional surgeries, or unresolved issues, and these were coded as either present or absent.</p><p><strong>Covariates: </strong>The covariates included age, sex, duration of symptoms, prior conservative therapies, history of previous open joint surgery, and Wilkes stage.</p><p><strong>Analyses: </strong>Data were analyzed using descriptive statistics with statistical significance set at P value <.05. χ<sup>2</sup> or Fisher's exact test was used depending on the variable type.</p><p><strong>Results: </strong>A total of 165 subjects (285 joints) with a mean age of 28.9 years (SD 13.0) were included. Of these, 149 (90.3%) were female and 16 (9.7%) were male. Level I procedures were performed on 37 joints (13.0%) in 23 subjects (16.3%), level II on 53 joints (18.6%) in 27 subjects (16.3%), and level III on 195 joints (68.4%) in 116 subjects (69.9%). Complications occurred only in level III (7 procedures, 2.5%, P = .33), affecting 5 subjects (3.0%). Observed complications included transient frontal facial paresis, mouth floor edema, transient neuropathic pain, suture rejection, and emphysema.</p><p><strong>Conclusion and relevance: </strong>The postoperative complication rate after arthroscopy was 2.5%, with no statistically significant association with operative complexity. Although more complications were observed in advanced arthroscopies, this increase was not significant.</p>","PeriodicalId":16612,"journal":{"name":"Journal of Oral and Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating Artificial Intelligence Chatbots in Oral and Maxillofacial Surgery Board Exams: Performance and Potential. 评估人工智能聊天机器人在口腔颌面外科委员会考试中的表现和潜力。
IF 2.3 3区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-11-19 DOI: 10.1016/j.joms.2024.11.007
Reema Mahmoud, Amir Shuster, Shlomi Kleinman, Shimrit Arbel, Clariel Ianculovici, Oren Peleg

Background: While artificial intelligence has significantly impacted medicine, the application of large language models (LLMs) in oral and maxillofacial surgery (OMS) remains underexplored.

Purpose: This study aimed to measure and compare the accuracy of 4 leading LLMs on OMS board examination questions and to identify specific areas for improvement.

Study design, setting, and sample: An in-silico cross-sectional study was conducted to evaluate 4 artificial intelligence chatbots on 714 OMS board examination questions.

Predictor variable: The predictor variable was the LLM used - LLM 1 (Generative Pretrained Transformer 4o [GPT-4o], OpenAI, San Francisco, CA), LLM 2 (Generative Pretrained Transformer 3.5 [GPT-3.5], OpenAI, San Francisco, CA), LLM 3 (Gemini, Google, Mountain View, CA), and LLM 4 (Copilot, Microsoft, Redmond, WA).

Main outcome variables: The primary outcome variable was accuracy, defined as the percentage of correct answers provided by each LLM. Secondary outcomes included the LLMs' ability to correct errors on subsequent attempts and their performance across 11 specific OMS subject domains: medicine and anesthesia, dentoalveolar and implant surgery, maxillofacial trauma, maxillofacial infections, maxillofacial pathology, salivary glands, oncology, maxillofacial reconstruction, temporomandibular joint anatomy and pathology, craniofacial and clefts, and orthognathic surgery.

Covariates: No additional covariates were considered.

Analyses: Statistical analysis included one-way ANOVA and post hoc Tukey honest significant difference (HSD) to compare performance across chatbots. χ2 tests were used to assess response consistency and error correction, with statistical significance set at P < .05.

Results: LLM 1 achieved the highest accuracy with an average score of 83.69%, statistically significantly outperforming LLM 3 (66.85%, P = .002), LLM 2 (64.83%, P = .001), and LLM 4 (62.18%, P < .001). Across the 11 OMS subject domains, LLM 1 consistently had the highest accuracy rates. LLM 1 also corrected 98.2% of errors, while LLM 2 corrected 93.44%, both statistically significantly higher than LLM 4 (29.26%) and LLM 3 (70.71%) (P < .001).

Conclusion and relevance: LLM 1 (GPT-4o) significantly outperformed other models in both accuracy and error correction, indicating its strong potential as a tool for enhancing OMS education. However, the variability in performance across different domains highlights the need for ongoing refinement and continued evaluation to integrate these LLMs more effectively into the OMS field.

背景:虽然人工智能对医学产生了重大影响,但大语言模型(LLMs)在口腔颌面外科(OMS)中的应用仍未得到充分探索。目的:本研究旨在衡量和比较4位领先法学硕士在OMS董事会考试问题上的准确性,并确定需要改进的具体领域。研究设计、设置和样本:通过计算机横断面研究,对4个人工智能聊天机器人在714道OMS考题上的表现进行评估。预测变量:预测变量是使用的LLM - llm1(生成式预训练的Transformer 40 [gpt - 40], OpenAI,旧金山,CA), llm2(生成式预训练的Transformer 3.5 [GPT-3.5], OpenAI,旧金山,CA), llm2 3 (Gemini,谷歌,Mountain View, CA)和llm2 4 (Copilot, Microsoft, Redmond, WA)。主要结果变量:主要结果变量为准确性,定义为每个LLM提供的正确答案的百分比。次要结果包括llm在后续尝试中纠正错误的能力,以及他们在11个特定OMS学科领域的表现:医学和麻醉、牙槽牙和种植外科、颌面创伤、颌面感染、颌面病理学、唾腺、肿瘤学、颌面重建、颞下颌关节解剖学和病理学、颅面和腭裂以及正颌外科。协变量:未考虑其他协变量。分析:统计分析包括单因素方差分析和事后Tukey HSD来比较聊天机器人的性能。结果:llm1的准确率最高,平均得分为83.69%,显著优于llm1 (66.85%, P = 0.002)、llm2 (64.83%, P = 0.001)和llm1(62.18%)。结论及相关性:llm1 (gpt - 40)在准确率和纠错率方面均显著优于其他模型,表明其作为OMS教育工具的潜力巨大。然而,不同领域的性能差异凸显了持续改进和持续评估的必要性,以便将这些llm更有效地整合到OMS领域。
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引用次数: 0
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Journal of Oral and Maxillofacial Surgery
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