Noor A Barakat, Rama AlGhanem, Bashar Abdulrazeq, Hatim S Alkhatib, S. A. Alryalat, Sana’ Muhsen, Suha A. Almuhaissen
The main objective of our study was to assess the adherence of Jordanian patients to their glaucoma treatment after a brief educational session. The current study was a randomized controlled interventional study. One hundred and ninety open-angle glaucoma patients were divided into control and intervention groups. After baseline assessment, patients in the intervention group received an educational session about glaucoma, while patients in the control group only received the usual care. Adherence to medication, eye drop administration technique, and knowledge about glaucoma were assessed at baseline and at follow-up. The mean MGL adherence scale score baseline value was 0.67 and significantly improved to 0.4 at the follow-up (P-value = .039) for patients in the intervention group. Multivariate regression showed that having less than three kids and experiencing glaucoma medication side effects were negatively correlated with adherence to glaucoma eye drops. The mean Eye Drops Administration scale score for patients in the intervention group improved significantly from 6.25 at baseline to 7.7 at the follow-up (P-value < .001). The mean knowledge scale score for the intervention group patients at baseline was 8.8, which significantly increased to 10 at the follow-up (P-value < .001). The knowledge score was found to be significantly higher for younger patients, those who have higher education levels and health care-related education, patients who rely on the ophthalmologist for glaucoma, and patients with a longer duration glaucoma. A short educational session improves patients’ adherence, knowledge, and eye drop administration technique in the intervention group significantly. Patients in Jordan have a relatively high adherence to glaucoma medications. Educational sessions should be provided to glaucoma patients to help the patients in managing their condition.
{"title":"Improving medication adherence in glaucoma patients: a randomized controlled interventional study","authors":"Noor A Barakat, Rama AlGhanem, Bashar Abdulrazeq, Hatim S Alkhatib, S. A. Alryalat, Sana’ Muhsen, Suha A. Almuhaissen","doi":"10.1093/jphsr/rmae003","DOIUrl":"https://doi.org/10.1093/jphsr/rmae003","url":null,"abstract":"\u0000 \u0000 \u0000 The main objective of our study was to assess the adherence of Jordanian patients to their glaucoma treatment after a brief educational session.\u0000 \u0000 \u0000 \u0000 The current study was a randomized controlled interventional study. One hundred and ninety open-angle glaucoma patients were divided into control and intervention groups. After baseline assessment, patients in the intervention group received an educational session about glaucoma, while patients in the control group only received the usual care. Adherence to medication, eye drop administration technique, and knowledge about glaucoma were assessed at baseline and at follow-up.\u0000 \u0000 \u0000 \u0000 The mean MGL adherence scale score baseline value was 0.67 and significantly improved to 0.4 at the follow-up (P-value = .039) for patients in the intervention group. Multivariate regression showed that having less than three kids and experiencing glaucoma medication side effects were negatively correlated with adherence to glaucoma eye drops. The mean Eye Drops Administration scale score for patients in the intervention group improved significantly from 6.25 at baseline to 7.7 at the follow-up (P-value < .001). The mean knowledge scale score for the intervention group patients at baseline was 8.8, which significantly increased to 10 at the follow-up (P-value < .001). The knowledge score was found to be significantly higher for younger patients, those who have higher education levels and health care-related education, patients who rely on the ophthalmologist for glaucoma, and patients with a longer duration glaucoma.\u0000 \u0000 \u0000 \u0000 A short educational session improves patients’ adherence, knowledge, and eye drop administration technique in the intervention group significantly. Patients in Jordan have a relatively high adherence to glaucoma medications. Educational sessions should be provided to glaucoma patients to help the patients in managing their condition.\u0000","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-28eCollection Date: 2024-03-01DOI: 10.1093/jphsr/rmae002
Yongbo Sim, Clayton F Hausberger, Junling Wang
Objectives: This study examined the effects of the comprehensive medication review of Medicare medication therapy management programs on opioid overuse among Medicare beneficiaries.
Methods: This retrospective study analyzed Medicare data from 2016 to 2017. The intervention group included Medicare beneficiaries who newly received comprehensive medication review in 2017; the control group referred to patients who met the general eligible criteria for the medication therapy management program but did not enroll in 2016 or 2017. Propensity score matching was performed to increase characteristic compatibility between the intervention and control groups. Three measures of opioid overuse were analyzed: use of opioids at a high dosage, use of opioids from multiple providers, and concurrent use of opioids and benzodiazepines. The effects of comprehensive medication review on opioid overuse were analyzed with a multivariate logistic regression with an interaction term between the receipt of comprehensive medication review and the year 2017.
Key findings: The proportion of concurrent use of opioids and benzodiazepines declined at a greater rate among the recipients (2.21%) than non-recipients (1.55%) of the comprehensive medication review. In the adjusted analysis, the odds ratio of no concurrent use of opioids and benzodiazepines was 5% higher (1.05; 95% confidence interval = 1.02-1.09) among recipients than non-recipients. These significant findings were not found for the other two measures of opioid overuse.
Conclusions: Comprehensive medication review is associated with reduced concurrent use of opioids and benzodiazepines among Medicare beneficiaries. Such service should be incorporated into the current approaches for addressing the opioid epidemic.
{"title":"Effects of comprehensive medication review on opioid overuse among medicare beneficiaries.","authors":"Yongbo Sim, Clayton F Hausberger, Junling Wang","doi":"10.1093/jphsr/rmae002","DOIUrl":"10.1093/jphsr/rmae002","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the effects of the comprehensive medication review of Medicare medication therapy management programs on opioid overuse among Medicare beneficiaries.</p><p><strong>Methods: </strong>This retrospective study analyzed Medicare data from 2016 to 2017. The intervention group included Medicare beneficiaries who newly received comprehensive medication review in 2017; the control group referred to patients who met the general eligible criteria for the medication therapy management program but did not enroll in 2016 or 2017. Propensity score matching was performed to increase characteristic compatibility between the intervention and control groups. Three measures of opioid overuse were analyzed: use of opioids at a high dosage, use of opioids from multiple providers, and concurrent use of opioids and benzodiazepines. The effects of comprehensive medication review on opioid overuse were analyzed with a multivariate logistic regression with an interaction term between the receipt of comprehensive medication review and the year 2017.</p><p><strong>Key findings: </strong>The proportion of concurrent use of opioids and benzodiazepines declined at a greater rate among the recipients (2.21%) than non-recipients (1.55%) of the comprehensive medication review. In the adjusted analysis, the odds ratio of no concurrent use of opioids and benzodiazepines was 5% higher (1.05; 95% confidence interval = 1.02-1.09) among recipients than non-recipients. These significant findings were not found for the other two measures of opioid overuse.</p><p><strong>Conclusions: </strong>Comprehensive medication review is associated with reduced concurrent use of opioids and benzodiazepines among Medicare beneficiaries. Such service should be incorporated into the current approaches for addressing the opioid epidemic.</p>","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139996548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. M. Shudifat, Sultan Mosleh, Suhair Almakhzomi, Mohammad Al Shdifat, Malek Alnajar, Ja’far M Alkhawaldeh, L. Al-Halaseh
To assess the level of perception and awareness of health science students towards using over-the-counter (OTC) medicines and reveal any malpractice. A descriptive cross-sectional correlational study employing an internet-based self-administered questionnaire collected data from 342 participants. The study model comprised four compartments: introductory, socio-demographic, utilizing OTC medications, and estimating the perception level. Descriptive statistics were used to describe participants’ demographics and main study variables. Non-parametric descriptive analysis and chi-squared tests were used to determine significance across the three medical schools. The response rate among students in their first academic year (33.9%) was the highest. Most participants rely on OTC to treat minor conditions like pain and the common cold. Nutraceuticals have been used heavily. The participants showed a positive attitude towards self-treatment; the average perception score was 3.45 (SD = 0.60; 95%CI: 3.38–3.51). Besides, participants on regularly prescribed medications still determined the interaction between their treatments and non-prescribed medications. No significant association between attitude average score and participant age (r = −0.06; P = .273). Likewise, no differences were found in perceived attitude towards OTC based on gender (P = .41), academic level (P = .223), and college (P = .84). This study provides an overview of the level of medical student’s perception towards self-treatment; despite the promising levels of knowledge and perception, it is necessitated to introduce interprofessional medical education to get an integrated knowledge and qualified graduates to provide the best health services.
{"title":"Measuring the knowledge and perception of Jordanian health science students towards self-prescribed medications: a descriptive analysis study","authors":"R. M. Shudifat, Sultan Mosleh, Suhair Almakhzomi, Mohammad Al Shdifat, Malek Alnajar, Ja’far M Alkhawaldeh, L. Al-Halaseh","doi":"10.1093/jphsr/rmad049","DOIUrl":"https://doi.org/10.1093/jphsr/rmad049","url":null,"abstract":"To assess the level of perception and awareness of health science students towards using over-the-counter (OTC) medicines and reveal any malpractice. A descriptive cross-sectional correlational study employing an internet-based self-administered questionnaire collected data from 342 participants. The study model comprised four compartments: introductory, socio-demographic, utilizing OTC medications, and estimating the perception level. Descriptive statistics were used to describe participants’ demographics and main study variables. Non-parametric descriptive analysis and chi-squared tests were used to determine significance across the three medical schools. The response rate among students in their first academic year (33.9%) was the highest. Most participants rely on OTC to treat minor conditions like pain and the common cold. Nutraceuticals have been used heavily. The participants showed a positive attitude towards self-treatment; the average perception score was 3.45 (SD = 0.60; 95%CI: 3.38–3.51). Besides, participants on regularly prescribed medications still determined the interaction between their treatments and non-prescribed medications. No significant association between attitude average score and participant age (r = −0.06; P = .273). Likewise, no differences were found in perceived attitude towards OTC based on gender (P = .41), academic level (P = .223), and college (P = .84). This study provides an overview of the level of medical student’s perception towards self-treatment; despite the promising levels of knowledge and perception, it is necessitated to introduce interprofessional medical education to get an integrated knowledge and qualified graduates to provide the best health services.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139209947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study aims to measure pharmacists’ knowledge and perception of celiac disease. A Google form was used to collect data randomly from 283 pharmacists. The effects of each of the following hypotheses towards early diagnosis of celiac disease and patient compliance were studied: pharmacist’s experience in community pharmacies (H1), pharmacist’s knowledge (H2), pharmacist’s participation in continuing learning programmes (H3), and pharmacist’s attitude and practice (H4). A robust relationship between the variables was confirmed and was expressed by the moderate mean effect of H1, H2, H3, and H4 (2.3332, 2.3386, 2.1731, and 2.5717, respectively, and the correlation coefficient [r] of 0.797). Findings suggest that H1 is moderately correlated with H2 and H3 but weakly correlated with H4 (0.568 and 0.518, 0.183, respectively). Around a third of the participants (33.9%) admit their lack of knowledge regarding the symptoms. A third of the participants would refer the patients with recurrent symptoms to the physician. Three-quarters of the participants (78.4%) have not attended any educational programme, but they show a high desire (84.1%) to participate in such events either in person (50.2%) or through distance learning applications (36.4%). Pharmacists have crucial roles in early diagnosis, monitoring patient compliance, and providing counselling regarding celiac disease. Updating their knowledge should contribute to improving the overall health status of the patients and cutting off the expenses for the health sector.
{"title":"Community pharmacists’ perception and role in early diagnosis and health promotion of celiac disease","authors":"Rawan Al-Suhaimat, L. Al-Halaseh, A. Al-Samydai","doi":"10.1093/jphsr/rmad048","DOIUrl":"https://doi.org/10.1093/jphsr/rmad048","url":null,"abstract":"The study aims to measure pharmacists’ knowledge and perception of celiac disease. A Google form was used to collect data randomly from 283 pharmacists. The effects of each of the following hypotheses towards early diagnosis of celiac disease and patient compliance were studied: pharmacist’s experience in community pharmacies (H1), pharmacist’s knowledge (H2), pharmacist’s participation in continuing learning programmes (H3), and pharmacist’s attitude and practice (H4). A robust relationship between the variables was confirmed and was expressed by the moderate mean effect of H1, H2, H3, and H4 (2.3332, 2.3386, 2.1731, and 2.5717, respectively, and the correlation coefficient [r] of 0.797). Findings suggest that H1 is moderately correlated with H2 and H3 but weakly correlated with H4 (0.568 and 0.518, 0.183, respectively). Around a third of the participants (33.9%) admit their lack of knowledge regarding the symptoms. A third of the participants would refer the patients with recurrent symptoms to the physician. Three-quarters of the participants (78.4%) have not attended any educational programme, but they show a high desire (84.1%) to participate in such events either in person (50.2%) or through distance learning applications (36.4%). Pharmacists have crucial roles in early diagnosis, monitoring patient compliance, and providing counselling regarding celiac disease. Updating their knowledge should contribute to improving the overall health status of the patients and cutting off the expenses for the health sector.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Good Pharmacy Practice (GPP) ensures access to quality medicines, a well-trained and adequate workforce of health professionals, and affordable healthcare. The Namibia Medicines Regulatory Council ensures the sale of medicines and the premises in which such sales are carried out comply with the Medicines and Related Substances Control Act of 2003. The purpose of this study was to report facility inspection outcomes. This was a retrospective review of inspection records archived over a period of 5 years (2017–2021) by the Namibia Medicines Regulatory Council. Compliance by facilities to 13 indicators as stipulated in the Namibia Medicines Regulatory Council inspections checklist adopted from international GPP guidelines was the main measure of outcomes. Results were summarized using descriptive statistics such as median, range, and percentages in R. The Mann–Whitney U test was used to compare medians. General compliance by community pharmacies (operated by pharmacists) was statistically higher (P = .0043) than dispensaries at clinics (mostly operated by nurses) with median (range) values of 84% (30.8–100) and 38% (0.0–100), respectively. There was an improvement in compliance over the 5 years for both pharmacies and clinics. The Ministry of Health & Social Services should implement policies that will ensure appropriately trained pharmaceutical cadres are stationed at all levels of the healthcare system to improve the delivery of pharmaceutical services. In addition, more inspectors need to be recruited for more frequent inspections.
{"title":"Outcomes of pharmacy facility inspections: implications on pharmaceutical services","authors":"B. Singu, Priscilla Mutsambiwa, Ester Mvula","doi":"10.1093/jphsr/rmad047","DOIUrl":"https://doi.org/10.1093/jphsr/rmad047","url":null,"abstract":"Good Pharmacy Practice (GPP) ensures access to quality medicines, a well-trained and adequate workforce of health professionals, and affordable healthcare. The Namibia Medicines Regulatory Council ensures the sale of medicines and the premises in which such sales are carried out comply with the Medicines and Related Substances Control Act of 2003. The purpose of this study was to report facility inspection outcomes. This was a retrospective review of inspection records archived over a period of 5 years (2017–2021) by the Namibia Medicines Regulatory Council. Compliance by facilities to 13 indicators as stipulated in the Namibia Medicines Regulatory Council inspections checklist adopted from international GPP guidelines was the main measure of outcomes. Results were summarized using descriptive statistics such as median, range, and percentages in R. The Mann–Whitney U test was used to compare medians. General compliance by community pharmacies (operated by pharmacists) was statistically higher (P = .0043) than dispensaries at clinics (mostly operated by nurses) with median (range) values of 84% (30.8–100) and 38% (0.0–100), respectively. There was an improvement in compliance over the 5 years for both pharmacies and clinics. The Ministry of Health & Social Services should implement policies that will ensure appropriately trained pharmaceutical cadres are stationed at all levels of the healthcare system to improve the delivery of pharmaceutical services. In addition, more inspectors need to be recruited for more frequent inspections.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139256977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background The practice of medication reconciliation by pharmacists is minimal in United Arab Emirates hospitals. Objectives To design an educational module for pharmacists on medication reconciliation and assess its feasibility. Methods The study consisted of three parts: A pre-educational module survey using a validated knowledge, perception, practice, and barriers questionnaire (Cronbach’s α = 0.78), delivery of the educational module, and participants’ feedback. An educational module (general introduction to medication reconciliation, what is medication reconciliation, how to do medication reconciliation, and practicing medication reconciliation) was developed based on Miller’s pyramid and validated by three experts and pilot-tested. The knowledge and perceptions of pharmacists were evaluated by comparing pre-post educational module survey results. Results The module influenced the participants’ knowledge and perception of medication reconciliation. All of the participants gave ‘positive’ feedback on the intervention and the methodology applied, and they agreed on the need for training and workshops related to medication reconciliation. In addition, all ‘agreed’ that a lack of knowledge about medication reconciliation is the biggest barrier to medication reconciliation practices. The results further illustrated that all pharmacists had a ‘positive’ experience and ‘agreed strongly’ on understanding the majority of the content. Conclusion This study was successful in answering the research question by enrolling suitable participants, managing the timeline, and possessing resources for completing the study and hence considered feasible. This module can be utilized in continuous professional development programs to improve pharmacists’ knowledge, perceptions, and practice toward the medication reconciliation process aiming to reduce drug therapy-related problems in hospital settings.
背景在阿联酋的医院中，药剂师进行药物调解的实践很少。目的设计药师用药和解教育模块，并对其可行性进行评估。方法采用经验证的知识、感知、实践和障碍问卷(Cronbach ' s α = 0.78)进行学前教育模块调查，进行教育模块的发放，并听取参与者的反馈。以米勒金字塔理论为基础，开发了一个教育模块(药物和解概论、什么是药物和解、如何进行药物和解、实践药物和解)，并经过三位专家的验证和试点测试。通过前后教育模块调查结果的比较，评价药师的知识和认知。结果该模块影响了被试对药物和解的认知和感知。所有的参与者都对干预措施和应用的方法给出了“积极”的反馈，他们同意需要进行与药物和解相关的培训和讲习班。此外，所有人都“同意”缺乏关于药物和解的知识是药物和解实践的最大障碍。结果进一步表明，所有药剂师都有一个“积极”的经验，并“强烈同意”理解大部分内容。本研究通过招募合适的参与者，管理时间线，拥有完成研究的资源，成功地回答了研究问题，因此认为是可行的。该模块可用于持续的专业发展计划，以提高药剂师的知识，观念和实践的药物调解过程，旨在减少在医院设置药物治疗相关问题。
{"title":"Development and feasibility of an educational module on medication reconciliation for hospital pharmacists in the United Arab Emirates: a pilot study","authors":"Alaa Farajallah, Hadzliana Zainal, Subish Palaian","doi":"10.1093/jphsr/rmad046","DOIUrl":"https://doi.org/10.1093/jphsr/rmad046","url":null,"abstract":"Abstract Background The practice of medication reconciliation by pharmacists is minimal in United Arab Emirates hospitals. Objectives To design an educational module for pharmacists on medication reconciliation and assess its feasibility. Methods The study consisted of three parts: A pre-educational module survey using a validated knowledge, perception, practice, and barriers questionnaire (Cronbach’s α = 0.78), delivery of the educational module, and participants’ feedback. An educational module (general introduction to medication reconciliation, what is medication reconciliation, how to do medication reconciliation, and practicing medication reconciliation) was developed based on Miller’s pyramid and validated by three experts and pilot-tested. The knowledge and perceptions of pharmacists were evaluated by comparing pre-post educational module survey results. Results The module influenced the participants’ knowledge and perception of medication reconciliation. All of the participants gave ‘positive’ feedback on the intervention and the methodology applied, and they agreed on the need for training and workshops related to medication reconciliation. In addition, all ‘agreed’ that a lack of knowledge about medication reconciliation is the biggest barrier to medication reconciliation practices. The results further illustrated that all pharmacists had a ‘positive’ experience and ‘agreed strongly’ on understanding the majority of the content. Conclusion This study was successful in answering the research question by enrolling suitable participants, managing the timeline, and possessing resources for completing the study and hence considered feasible. This module can be utilized in continuous professional development programs to improve pharmacists’ knowledge, perceptions, and practice toward the medication reconciliation process aiming to reduce drug therapy-related problems in hospital settings.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135291673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski
{"title":"Time to treat the climate and nature crisis as one indivisible global health emergency","authors":"Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski","doi":"10.1093/jphsr/rmad045","DOIUrl":"https://doi.org/10.1093/jphsr/rmad045","url":null,"abstract":"","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135219222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zainab M Al-Shammaa, Mohammed I Aladul, Narmin S Essa
Abstract Objectives Neuropathic pain (NP) is a type of chronic pain. Numerous diseases and/or lesions are associated with the development of NP, and diabetes mellitus is the most prevalent cause. Several classes of medications were recommended and/or approved as anti-neuropathic medications. This study aimed to examine the trends in the turnover of anti-neuropathic medications in Iraq. Methods This was a retrospective analysis of the turnover of selected anti-neuropathic medications in the Iraqi market derived from Advanced Marketing Statistics between 2017 and 2021. The sales units were converted to defined daily doses. Regression analysis and correlation analysis were used to compare the turnover of the medications. Key findings The overall volume of turnover of anti-neuropathic medications increased between 2017 and 2021. The anti-neuropathic market domination was shifted from carbamazepine to pregabalin, in which the average increase in pregabalin turnover of 60% [95% CI (confidence interval) 37.6–82.5] quarterly to achieve 42% of the market share (highest sales) by 2021. The overall expenditure on anti-neuropathic medications increased steadily over the study period. Conclusions The market of anti-neuropathic medications’ domination was shifted from the older antiepileptic drug (AED) (carbamazepine) to the newer AED (pregabalin). The availability and affordability of less expensive generic versions of these agents, together with the better safety profiles of the newer agents were the main driver for this shift. This indeed allowed Iraqi physicians to adhere to the latest international guidelines.
{"title":"Trends in anti-neuropathic medications turnover in Iraq","authors":"Zainab M Al-Shammaa, Mohammed I Aladul, Narmin S Essa","doi":"10.1093/jphsr/rmad042","DOIUrl":"https://doi.org/10.1093/jphsr/rmad042","url":null,"abstract":"Abstract Objectives Neuropathic pain (NP) is a type of chronic pain. Numerous diseases and/or lesions are associated with the development of NP, and diabetes mellitus is the most prevalent cause. Several classes of medications were recommended and/or approved as anti-neuropathic medications. This study aimed to examine the trends in the turnover of anti-neuropathic medications in Iraq. Methods This was a retrospective analysis of the turnover of selected anti-neuropathic medications in the Iraqi market derived from Advanced Marketing Statistics between 2017 and 2021. The sales units were converted to defined daily doses. Regression analysis and correlation analysis were used to compare the turnover of the medications. Key findings The overall volume of turnover of anti-neuropathic medications increased between 2017 and 2021. The anti-neuropathic market domination was shifted from carbamazepine to pregabalin, in which the average increase in pregabalin turnover of 60% [95% CI (confidence interval) 37.6–82.5] quarterly to achieve 42% of the market share (highest sales) by 2021. The overall expenditure on anti-neuropathic medications increased steadily over the study period. Conclusions The market of anti-neuropathic medications’ domination was shifted from the older antiepileptic drug (AED) (carbamazepine) to the newer AED (pregabalin). The availability and affordability of less expensive generic versions of these agents, together with the better safety profiles of the newer agents were the main driver for this shift. This indeed allowed Iraqi physicians to adhere to the latest international guidelines.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135218554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofa D Alfian, Qisty A Khoiry, Mochammad A A Pratama, Wawan Wahyudin, Irma M Puspitasari, Ivan S Pradipta, Rizky Abdulah
Abstract Objective To assess the awareness and beliefs of community pharmacists regarding the disposal of expired and unused household medications in Indonesia. Methods A cross-sectional survey was conducted through convenience sampling. All pharmacists participating in a virtual training event were invited to take part in a self-administer voluntary online survey. A translated and validated questionnaire was used to assess awareness about the harm caused by improper disposal and the beliefs of the best location for collecting expired and unused household medications. Subsequently, demographic data such as age, gender, education level, and work experience of pharmacists were obtained through self-reported data. The characteristics of pharmacists and the outcomes were summarized using descriptive analysis. Correlation analysis was carried out to determine the association between sociodemographic variables and outcomes. Key findings A total of 202 pharmacists completed the survey (response rate: 96.2%). The majority were female (83.2%) and the mean work experience was 4.7 years. Approximately 86% of pharmacists were aware of the environmental harm caused by improper disposing of expired and unused household medications, and 98% acknowledged their role in preventing such risks. Approximately 70%–80% of the respondents believed that community pharmacies were the best location for the collection of expired and unused household medications. No significant associations were found among age, gender, education level, and years of experience and the outcomes. Conclusion Almost all pharmacists were aware of the risk of improper disposal of expired and unused household medications and acknowledged their responsibilities to protect the environment. The strong inclination of pharmacists to select pharmacies as collection points for expired and unused medications strongly advocates for the implementation of medication take-back programs in Indonesia.
{"title":"Awareness and beliefs of community pharmacists on disposal of unused and expired household medications in Indonesia: a cross-sectional study","authors":"Sofa D Alfian, Qisty A Khoiry, Mochammad A A Pratama, Wawan Wahyudin, Irma M Puspitasari, Ivan S Pradipta, Rizky Abdulah","doi":"10.1093/jphsr/rmad043","DOIUrl":"https://doi.org/10.1093/jphsr/rmad043","url":null,"abstract":"Abstract Objective To assess the awareness and beliefs of community pharmacists regarding the disposal of expired and unused household medications in Indonesia. Methods A cross-sectional survey was conducted through convenience sampling. All pharmacists participating in a virtual training event were invited to take part in a self-administer voluntary online survey. A translated and validated questionnaire was used to assess awareness about the harm caused by improper disposal and the beliefs of the best location for collecting expired and unused household medications. Subsequently, demographic data such as age, gender, education level, and work experience of pharmacists were obtained through self-reported data. The characteristics of pharmacists and the outcomes were summarized using descriptive analysis. Correlation analysis was carried out to determine the association between sociodemographic variables and outcomes. Key findings A total of 202 pharmacists completed the survey (response rate: 96.2%). The majority were female (83.2%) and the mean work experience was 4.7 years. Approximately 86% of pharmacists were aware of the environmental harm caused by improper disposing of expired and unused household medications, and 98% acknowledged their role in preventing such risks. Approximately 70%–80% of the respondents believed that community pharmacies were the best location for the collection of expired and unused household medications. No significant associations were found among age, gender, education level, and years of experience and the outcomes. Conclusion Almost all pharmacists were aware of the risk of improper disposal of expired and unused household medications and acknowledged their responsibilities to protect the environment. The strong inclination of pharmacists to select pharmacies as collection points for expired and unused medications strongly advocates for the implementation of medication take-back programs in Indonesia.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135779012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bayan M Hijazi, Ioana Popovici, Mohammad B Nusair, Goar Alvarez
Abstract Objectives To assess the patterns and risk factors associated with selective serotonin reuptake inhibitor (SSRI) medication adherence among enrollees of a multiple employer welfare beneficiary association operating in Florida. Methods This study used a pharmacy claims database for beneficiaries of the Independent Colleges and Universities Benefits Association. The sample of 2541 patients were enrollees who filled two or more consecutive SSRI prescriptions during the analysis period 2015–20. Adherence was measured as the proportion of days covered by a medication. Multiple logistic regression analysis was used to explore the relationship between sociodemographic, healthcare access, and clinical and medication-related factors and adherence. Key findings Adherence was associated with higher odds of being female [odds ratio (OR): 1.2, 95% confidence interval (CI): 0.995–1.464, P < .10] and higher pill burden (OR: 1.3, CI: 1.021–1.642, P< 0.05). Patients using only retail pharmacies (OR: 0.356, CI: 0.196–0.645, P < .01), having any out-of-pocket costs (OR: 0.552, CI: 0.348–0.875, P < .50), changing the prescriber over the duration of the treatment (OR: 0.708, CI: 0.589–0.851, P < .01), taking antihypertensive (OR: 0.708, CI: 0.5077–0.988, P < 0.50), and asthma (OR: 0.609, CI: 0.450–0.826, P < .01) medications were less likely to be adherent. Prescriber specialty was not found to be associated with adherence. Conclusion These findings can inform policymakers and healthcare insurance companies on barriers to medication access and recommend strategies to eliminate these barriers and design interventions to improve the adherence of groups at risk for nonadherence. Healthcare providers can identify patients who are less likely to be adherent and customize counseling interventions for these patients.
【摘要】目的评估佛罗里达州一家多雇主福利受益人协会参保人员选择性血清素再摄取抑制剂(SSRI)药物依从性的模式和危险因素。方法本研究使用独立学院和大学福利协会受益人的药房索赔数据库。2541例患者是在2015 - 2020年分析期间连续服用两次或两次以上SSRI处方的入组患者。依从性以服药天数的比例来衡量。采用多元logistic回归分析探讨社会人口学、医疗保健可及性、临床和药物相关因素与依从性之间的关系。依从性与女性的高几率相关[优势比(OR): 1.2, 95%可信区间(CI): 0.995-1.464, P <[10.10]和较高的药丸负担(OR: 1.3, CI: 1.021-1.642, p&p;0.05)。仅使用零售药店的患者(OR: 0.356, CI: 0.196-0.645, P <0.01)，有任何自付费用(OR: 0.552, CI: 0.348-0.875, P <0.50)，在治疗期间改变处方者(OR: 0.708, CI: 0.589-0.851, P <0.01)，服用抗高血压药物(OR: 0.708, CI: 0.5077 ~ 0.988, P <0.50)，哮喘(OR: 0.609, CI: 0.450-0.826, P <.01)药物的依从性较低。未发现处方医师专业与依从性相关。结论这些发现可以为政策制定者和医疗保险公司提供药物获取障碍的信息，并建议消除这些障碍的策略和设计干预措施，以提高有不依从风险群体的依从性。医疗保健提供者可以识别不太可能坚持的患者，并为这些患者定制咨询干预措施。
{"title":"Patterns and factors associated with SSRI medication adherence: a retrospective study using pharmacy claims data","authors":"Bayan M Hijazi, Ioana Popovici, Mohammad B Nusair, Goar Alvarez","doi":"10.1093/jphsr/rmad041","DOIUrl":"https://doi.org/10.1093/jphsr/rmad041","url":null,"abstract":"Abstract Objectives To assess the patterns and risk factors associated with selective serotonin reuptake inhibitor (SSRI) medication adherence among enrollees of a multiple employer welfare beneficiary association operating in Florida. Methods This study used a pharmacy claims database for beneficiaries of the Independent Colleges and Universities Benefits Association. The sample of 2541 patients were enrollees who filled two or more consecutive SSRI prescriptions during the analysis period 2015–20. Adherence was measured as the proportion of days covered by a medication. Multiple logistic regression analysis was used to explore the relationship between sociodemographic, healthcare access, and clinical and medication-related factors and adherence. Key findings Adherence was associated with higher odds of being female [odds ratio (OR): 1.2, 95% confidence interval (CI): 0.995–1.464, P &lt; .10] and higher pill burden (OR: 1.3, CI: 1.021–1.642, P&lt; 0.05). Patients using only retail pharmacies (OR: 0.356, CI: 0.196–0.645, P &lt; .01), having any out-of-pocket costs (OR: 0.552, CI: 0.348–0.875, P &lt; .50), changing the prescriber over the duration of the treatment (OR: 0.708, CI: 0.589–0.851, P &lt; .01), taking antihypertensive (OR: 0.708, CI: 0.5077–0.988, P &lt; 0.50), and asthma (OR: 0.609, CI: 0.450–0.826, P &lt; .01) medications were less likely to be adherent. Prescriber specialty was not found to be associated with adherence. Conclusion These findings can inform policymakers and healthcare insurance companies on barriers to medication access and recommend strategies to eliminate these barriers and design interventions to improve the adherence of groups at risk for nonadherence. Healthcare providers can identify patients who are less likely to be adherent and customize counseling interventions for these patients.","PeriodicalId":16705,"journal":{"name":"Journal of Pharmaceutical Health Services Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135855353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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