Pub Date : 2023-12-23DOI: 10.9734/jpri/2023/v35i337476
Mohammed Abdulaziz Kareem, Khalid Mohammed Alzahrani, A. S. Alshehri, Nedal Jamal A. Almasri, Wael Abdi Almutairi, Adel Saed Alghamdi
Background: Chemical poisoning is a major health issue. This study aimed to assess and evaluate the reporting system of chemical poisoning and drug safety program (CSP) in the governmental and private hospitals in Jeddah city, Saudi Arabia. Methods: This descriptive and analytical cross-sectional study was conducted in Jeddah city, Saudi Arabia in the period from January to June 2022. we included 30 governmental and private hospitals that included more than 150 beds. To collect data, this study used a 17-item evaluation form that was approved and used by the Saudi Ministry of Health to evaluate the reporting systems in the hospitals in the country. Results: Regarding the Reporting system in the public health departments (PHD), the Ministry of Health (MOH) memo for reporting cases of chemical and drug overdose is present in 80% of the hospitals, 30% reported that samples sent to the toxicology center are received. Regarding the Reporting system in the emergency department, 46.7% reported that death cases are immediately reported to the PHD. Regarding the Reporting system in hospital laboratory, 46.5% reported that chemical and drug overdose samples are sent to the Toxicology Center. Reporting system in the public health department and Reporting system in the emergency department were better in the Private hospitals (p =0.042 and p=0.045, respectively). Conclusion: Low adherence was found in the recruited hospitals. Less adherence was found in the governmental hospitals, particularly in the reporting system in the public health departments and the reporting system in the emergency departments. Some hospitals scored low in the three domains of the evaluation form.
{"title":"Evaluation of the Reporting System of Chemical Poisoning and Drug Safety Program in the Governmental and Private Hospitals in Jeddah City, Saudi Arabia, A Cross-Sectional Study","authors":"Mohammed Abdulaziz Kareem, Khalid Mohammed Alzahrani, A. S. Alshehri, Nedal Jamal A. Almasri, Wael Abdi Almutairi, Adel Saed Alghamdi","doi":"10.9734/jpri/2023/v35i337476","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i337476","url":null,"abstract":"Background: Chemical poisoning is a major health issue. This study aimed to assess and evaluate the reporting system of chemical poisoning and drug safety program (CSP) in the governmental and private hospitals in Jeddah city, Saudi Arabia. Methods: This descriptive and analytical cross-sectional study was conducted in Jeddah city, Saudi Arabia in the period from January to June 2022. we included 30 governmental and private hospitals that included more than 150 beds. To collect data, this study used a 17-item evaluation form that was approved and used by the Saudi Ministry of Health to evaluate the reporting systems in the hospitals in the country. Results: Regarding the Reporting system in the public health departments (PHD), the Ministry of Health (MOH) memo for reporting cases of chemical and drug overdose is present in 80% of the hospitals, 30% reported that samples sent to the toxicology center are received. Regarding the Reporting system in the emergency department, 46.7% reported that death cases are immediately reported to the PHD. Regarding the Reporting system in hospital laboratory, 46.5% reported that chemical and drug overdose samples are sent to the Toxicology Center. Reporting system in the public health department and Reporting system in the emergency department were better in the Private hospitals (p =0.042 and p=0.045, respectively). Conclusion: Low adherence was found in the recruited hospitals. Less adherence was found in the governmental hospitals, particularly in the reporting system in the public health departments and the reporting system in the emergency departments. Some hospitals scored low in the three domains of the evaluation form.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"15 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139162519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-22DOI: 10.9734/jpri/2023/v35i337473
Mahmoud S. Babiker, Awatif M Omer, Amel F. Alzain, Meaad Elbashir, Rufida E. Ahmed, Omima Adam Ahmed, Esra Salam Mohamed
Objective: To assess the incidence of the associated meniscal ligament (ML) with the anterior cruciate ligament (ACL) tears in hospital A in Medina-KSA. And to see the effect of sports activities in comparison between males and females. Materials and Methods: In a retrospective study, ninety-nine patients' knee magnetic resonance imaging (MRI) records were selected conveniently from the (A) hospital's picture archiving and communication system (PACS). Patients with suspected anterior cruciate and meniscal ligament' tears were included. Patients with posterior cruciate ligament (PCL) tear, medial collateral ligament (MCL) or lateral collateral ligament (LCL) injury, and previously operated index knees were excluded. All patients were scanned by a 1.5T MRI machine using standard MRI knee scanning protocol. The categorical and continuous variables were presented as percentages, frequencies, and descriptive statistics. The cross-tabulations and chi-square test were applied to obtain the statistical associations between the study variables. A statistical association was considered significant if the P-value was < 0.05. Results: 72 males and 27 females were included, with a mean age of 33 ± 2.43. 42.4% of the knee tears were ML tears, followed by associated (ACL with ML) tears, noted in 31.3%, and 26.3% were ACL tears. The tears were more frequent in the age group (31-40), reported in 35.3% (out of 99). There was no statistical association between the tears and the participants' age, gender, or sports activities; P value = 0.3, 0.5, and 0.9, respectively. Conclusion: The study concluded that the isolated ML tears were more frequent than the associated (ACL with ML) tears—moreover, there was no significant statistical association between the participants' age, gender, or sports activities.
{"title":"The Incidence of the Associated Meniscal Ligament (ML) With the Anterior Cruciate Ligament (ACL) Tears","authors":"Mahmoud S. Babiker, Awatif M Omer, Amel F. Alzain, Meaad Elbashir, Rufida E. Ahmed, Omima Adam Ahmed, Esra Salam Mohamed","doi":"10.9734/jpri/2023/v35i337473","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i337473","url":null,"abstract":"Objective: To assess the incidence of the associated meniscal ligament (ML) with the anterior cruciate ligament (ACL) tears in hospital A in Medina-KSA. And to see the effect of sports activities in comparison between males and females. Materials and Methods: In a retrospective study, ninety-nine patients' knee magnetic resonance imaging (MRI) records were selected conveniently from the (A) hospital's picture archiving and communication system (PACS). Patients with suspected anterior cruciate and meniscal ligament' tears were included. Patients with posterior cruciate ligament (PCL) tear, medial collateral ligament (MCL) or lateral collateral ligament (LCL) injury, and previously operated index knees were excluded. All patients were scanned by a 1.5T MRI machine using standard MRI knee scanning protocol. The categorical and continuous variables were presented as percentages, frequencies, and descriptive statistics. The cross-tabulations and chi-square test were applied to obtain the statistical associations between the study variables. A statistical association was considered significant if the P-value was < 0.05. Results: 72 males and 27 females were included, with a mean age of 33 ± 2.43. 42.4% of the knee tears were ML tears, followed by associated (ACL with ML) tears, noted in 31.3%, and 26.3% were ACL tears. The tears were more frequent in the age group (31-40), reported in 35.3% (out of 99). There was no statistical association between the tears and the participants' age, gender, or sports activities; P value = 0.3, 0.5, and 0.9, respectively. Conclusion: The study concluded that the isolated ML tears were more frequent than the associated (ACL with ML) tears—moreover, there was no significant statistical association between the participants' age, gender, or sports activities.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"86 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139163262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-21DOI: 10.9734/jpri/2023/v35i327471
Akash Sharma, Chandra Prakash, Ankur Vora
This paper explores the pivotal role of syringes in the era of precision medicine, shedding light on their historical significance, technological advancements, and the profound impact they have on healthcare quality. By delving into the design features of precision syringes and their application in various medical fields, this paper aims to underline the critical role these instruments play in achieving optimal patient outcomes. The discussion also addresses challenges, solutions, and the regulatory landscape, offering a comprehensive overview of the synergy between syringes and precision medicine.
{"title":"Injecting Quality Care: Syringes and their Impact on Precision Medicine in Healthcare","authors":"Akash Sharma, Chandra Prakash, Ankur Vora","doi":"10.9734/jpri/2023/v35i327471","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i327471","url":null,"abstract":"This paper explores the pivotal role of syringes in the era of precision medicine, shedding light on their historical significance, technological advancements, and the profound impact they have on healthcare quality. By delving into the design features of precision syringes and their application in various medical fields, this paper aims to underline the critical role these instruments play in achieving optimal patient outcomes. The discussion also addresses challenges, solutions, and the regulatory landscape, offering a comprehensive overview of the synergy between syringes and precision medicine.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"25 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139166108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-21DOI: 10.9734/jpri/2023/v35i337472
Sarangal Vandana, Goyal Pankaj, S. Tej, Kaur Supreet, Suchdev Vasudha
Aim: The present study was conducted to assess the role of vitamin C in wound healing following dental implant surgery. Materials and Methods: 60 patients receiving dental implants were divided into two groups of 30 each. group A and group B. Group A included 30 patients who underwent dental implant surgery along with vitamin C supplementation, 500 mg twice a day post-surgery for 5 days and group B included 30 patients who underwent dental implant surgery alone. The Wound Healing Index, Wound Evaluation score and Visual Analog Scale were the following indices evaluated. Results: The results of the present study showed that there was a significant improvement in all indices in both group A and group B, but results in group A were statistically more significant than group B and indicating that maximum healing was seen in the first 7 days post-operative, thereafter, remaining more or less the same. In reference to vitamin C for pain relief, there was no statistically difference between the study groups. Conclusion: Using vitamin C supplementation post-operative healing following dental implant surgery in patients given vitamin C. However, vitamin C supplementation does not decrease the post operative pain associated with dental pain and anxiety.
目的：本研究旨在评估维生素 C 在牙科种植手术后伤口愈合中的作用。 材料和方法：将 60 名接受牙科种植手术的患者分为两组，每组 30 人，A 组和 B 组。A 组包括 30 名接受牙科种植手术的患者，他们在接受手术的同时补充维生素 C，每天两次，每次 500 毫克，连续 5 天；B 组包括 30 名仅接受牙科种植手术的患者。评估指标包括伤口愈合指数、伤口评估评分和视觉模拟量表。 结果显示本研究结果显示，A 组和 B 组的所有指数均有明显改善，但 A 组的结果在统计学上比 B 组更为显著，表明术后头 7 天的愈合程度最高，此后则基本保持不变。至于维生素 C 的止痛作用，研究组之间没有统计学差异。 结论但补充维生素 C 并不能减轻与牙痛和焦虑相关的术后疼痛。
{"title":"Evaluation of Effects of Vitamin C Supplementation in Wound Healing Post Dental Implant Surgery: A Clinical Study","authors":"Sarangal Vandana, Goyal Pankaj, S. Tej, Kaur Supreet, Suchdev Vasudha","doi":"10.9734/jpri/2023/v35i337472","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i337472","url":null,"abstract":"Aim: The present study was conducted to assess the role of vitamin C in wound healing following dental implant surgery. Materials and Methods: 60 patients receiving dental implants were divided into two groups of 30 each. group A and group B. Group A included 30 patients who underwent dental implant surgery along with vitamin C supplementation, 500 mg twice a day post-surgery for 5 days and group B included 30 patients who underwent dental implant surgery alone. The Wound Healing Index, Wound Evaluation score and Visual Analog Scale were the following indices evaluated. Results: The results of the present study showed that there was a significant improvement in all indices in both group A and group B, but results in group A were statistically more significant than group B and indicating that maximum healing was seen in the first 7 days post-operative, thereafter, remaining more or less the same. In reference to vitamin C for pain relief, there was no statistically difference between the study groups. Conclusion: Using vitamin C supplementation post-operative healing following dental implant surgery in patients given vitamin C. However, vitamin C supplementation does not decrease the post operative pain associated with dental pain and anxiety.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"20 S5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139167119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.9734/jpri/2023/v35i327470
Trupthi N. Rane, Rama Bhat P.
Mammea suriga is a familiar endemic medicinal plant belonging to the family Guttiferae/Clusiaceae, grows abundantly in the Western Ghats of India. The present investigation focuses on studying the phytoconstituents as well as antioxidant and antimicrobial properties of bark and leaf extracts. Phytochemical screening showed the presence of carbohydrates, phenolics, flavonoids, alkaloids, cardiac glycosides, terpenoids, triterpenoids, steroids and saponins. The carbohydrate contents were highest in leaf methanol (140.90 ± 1.19 mg/g), phenolic contents highest in leaf methanol (154.32 ± 1.80 mg/g), the highest flavonoid content were observed in bark aqueous extract (437.3878 ± 0.09mg/g). In the antioxidant screening assay, the highest inhibition concentration was found to be IC50 (53.33 ± 0.13) for leaf methanol for DPPH, highest ferric reducing activity was observed in both the bark extracts at 300μg/mL concentrations, antioxidant activity for phoshomolybdenum assay was observed highest (75%) in leaf methanol extract at 300μg/mL. Antibacterial activity was carried out by agar well diffusion method using extracts against E. coli, K. pneumoniae, P. aeruginosa and S. aureus which showed inhibition zone diameter ranging from 12-22mm. Antifungal test by poison bait method against Fusarium solani and Colletotrichum gloeosporioides have shown good results.
{"title":"Pharmaceutical Studies of Leaf and Bark Extracts of Mammea suriga (Buch.-Ham. ex Roxb.) Kosterm.","authors":"Trupthi N. Rane, Rama Bhat P.","doi":"10.9734/jpri/2023/v35i327470","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i327470","url":null,"abstract":"Mammea suriga is a familiar endemic medicinal plant belonging to the family Guttiferae/Clusiaceae, grows abundantly in the Western Ghats of India. The present investigation focuses on studying the phytoconstituents as well as antioxidant and antimicrobial properties of bark and leaf extracts. Phytochemical screening showed the presence of carbohydrates, phenolics, flavonoids, alkaloids, cardiac glycosides, terpenoids, triterpenoids, steroids and saponins. The carbohydrate contents were highest in leaf methanol (140.90 ± 1.19 mg/g), phenolic contents highest in leaf methanol (154.32 ± 1.80 mg/g), the highest flavonoid content were observed in bark aqueous extract (437.3878 ± 0.09mg/g). In the antioxidant screening assay, the highest inhibition concentration was found to be IC50 (53.33 ± 0.13) for leaf methanol for DPPH, highest ferric reducing activity was observed in both the bark extracts at 300μg/mL concentrations, antioxidant activity for phoshomolybdenum assay was observed highest (75%) in leaf methanol extract at 300μg/mL. Antibacterial activity was carried out by agar well diffusion method using extracts against E. coli, K. pneumoniae, P. aeruginosa and S. aureus which showed inhibition zone diameter ranging from 12-22mm. Antifungal test by poison bait method against Fusarium solani and Colletotrichum gloeosporioides have shown good results.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138994771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-16DOI: 10.9734/jpri/2023/v35i327469
Waseem Mohammed Alkhaldi, Ohoud Fouad Abuatallah, Nesreen Abdullah AL-Ghamdi, Bandar Allahyani, Salman Safar Alghamdi, Mohammed Ali Alqarni, Ibrahim Abdullah Alzahrani
Aim: This study aims to investigate the influence of social work services on the quality of care at Eradah and Mental Health Complex in Jeddah. Duration of the Study: This study employs one year of conduction from December 2022 to November 2023. Methods: A cross-sectional study was conducted using the SERVQUL questionnaire as the main scale to assess the degree of social work influence on the overall quality of the healthcare setting to be distributed among selected healthcare workers. Results: Among randomly selected 240 healthcare workers, among these, 20.8% were aged between 25 and 30 years, the majority (68.3%) were male, about 45.4% had a bachelor’s degree, also, about 67.5% of them were married, 52.5% were laboratory technicians. The results indicated a moderate healthcare rating with a mean score of 58.29 and a moderate healthcare adherence rating with a mean score of 98.37. The results revealed a significant difference in the quality of healthcare among patients due to education (P-value =0.012) and there was a significant difference with job title (p-value = 0.001). However, no significant differences were observed about age, or marital status. Conclusion: It can be concluded that social work is a crucial type of work that must be implemented among healthcare workers to enhance cooperation and serve society, it has been found that healthcare adherence was rated as moderate. Nevertheless, variables such as age, gender, education level, and marital status did not exert a substantial impact.
{"title":"The Impact of Social Work Services on the Quality of Care in Mental Health Complex in Jeddah: A Study of Healthcare Professionals’ Perceptions","authors":"Waseem Mohammed Alkhaldi, Ohoud Fouad Abuatallah, Nesreen Abdullah AL-Ghamdi, Bandar Allahyani, Salman Safar Alghamdi, Mohammed Ali Alqarni, Ibrahim Abdullah Alzahrani","doi":"10.9734/jpri/2023/v35i327469","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i327469","url":null,"abstract":"Aim: This study aims to investigate the influence of social work services on the quality of care at Eradah and Mental Health Complex in Jeddah. \u0000Duration of the Study: This study employs one year of conduction from December 2022 to November 2023. \u0000Methods: A cross-sectional study was conducted using the SERVQUL questionnaire as the main scale to assess the degree of social work influence on the overall quality of the healthcare setting to be distributed among selected healthcare workers. \u0000Results: Among randomly selected 240 healthcare workers, among these, 20.8% were aged between 25 and 30 years, the majority (68.3%) were male, about 45.4% had a bachelor’s degree, also, about 67.5% of them were married, 52.5% were laboratory technicians. The results indicated a moderate healthcare rating with a mean score of 58.29 and a moderate healthcare adherence rating with a mean score of 98.37. The results revealed a significant difference in the quality of healthcare among patients due to education (P-value =0.012) and there was a significant difference with job title (p-value = 0.001). However, no significant differences were observed about age, or marital status. \u0000Conclusion: It can be concluded that social work is a crucial type of work that must be implemented among healthcare workers to enhance cooperation and serve society, it has been found that healthcare adherence was rated as moderate. Nevertheless, variables such as age, gender, education level, and marital status did not exert a substantial impact.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"56 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.9734/jpri/2023/v35i327468
Wajdi Alansari, Abdullah Hasan Alshaikhi, Mohanna Almutairi, Dalia Khalid H. Kaki, Ali Ghurmullah Alzahrani
Aim: This review aimed to assess the correlation between nurses’ exposure to psychosocial stressors and the occurrence of medical and medication errors in some hospitals of Jeddah and its correlation to other hospitals. Methods: The study utilized a range of approaches. To conduct a thorough literature search, a total of five databases CINAHL, PubMed, COCHRANE, Google Scholar and Web of Science were employed. Results: Using date filters, we ensured that the literature we retrieved was accurate and up to date for the last 5 years across all databases to ensure updated deep analysis evidence to find that from a total of 6019 studies, only seventeen studies were relevant to this review to be analyzed and discussed to find that to mitigate the likelihood of medical incidents/errors, it is imperative to consider factors such as current/recent illness, bodily discomfort, and emotional role as personal challenges for nurses. Additionally, addressing break periods during the night shift and working conditions as administrative concerns is crucial. Conclusion: Research has demonstrated that medical errors constitute the most widespread kind of errors, posing a significant risk to patient safety. Many psychological factors are concerned with rising rates of errors among nurses. The implementation of proactive methods is a successful approach to mitigating medical errors within healthcare settings.
目的：本综述旨在评估吉达一些医院的护士所面临的社会心理压力与医疗和用药错误发生率之间的相关性及其与其他医院的相关性。研究方法：本研究采用了一系列方法。为了进行全面的文献检索，共使用了 CINAHL、PubMed、COCHRANE、Google Scholar 和 Web of Science 五个数据库。结果通过使用日期过滤器，我们确保检索到的所有数据库中过去 5 年的文献都是准确的、最新的，以确保获得最新的深度分析证据，结果发现，在总共 6019 项研究中，只有 17 项研究与本综述相关，我们对这些研究进行了分析和讨论，发现要降低医疗事故/差错发生的可能性，必须考虑护士当前/近期的疾病、身体不适和情感角色等因素，将其视为个人挑战。此外，解决夜班休息时间和工作条件等行政问题也至关重要。结论：研究表明，医疗差错是最普遍的差错类型，对患者安全构成重大风险。护士出错率的上升与许多心理因素有关。采取积极主动的方法是减少医疗机构医疗差错的成功途径。
{"title":"Medical Error’ Incidence and Its Relation to Psychological Stressors among Nurses in Jeddah, Saudi Arabia","authors":"Wajdi Alansari, Abdullah Hasan Alshaikhi, Mohanna Almutairi, Dalia Khalid H. Kaki, Ali Ghurmullah Alzahrani","doi":"10.9734/jpri/2023/v35i327468","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i327468","url":null,"abstract":"Aim: This review aimed to assess the correlation between nurses’ exposure to psychosocial stressors and the occurrence of medical and medication errors in some hospitals of Jeddah and its correlation to other hospitals. \u0000Methods: The study utilized a range of approaches. To conduct a thorough literature search, a total of five databases CINAHL, PubMed, COCHRANE, Google Scholar and Web of Science were employed. \u0000Results: Using date filters, we ensured that the literature we retrieved was accurate and up to date for the last 5 years across all databases to ensure updated deep analysis evidence to find that from a total of 6019 studies, only seventeen studies were relevant to this review to be analyzed and discussed to find that to mitigate the likelihood of medical incidents/errors, it is imperative to consider factors such as current/recent illness, bodily discomfort, and emotional role as personal challenges for nurses. Additionally, addressing break periods during the night shift and working conditions as administrative concerns is crucial. \u0000Conclusion: Research has demonstrated that medical errors constitute the most widespread kind of errors, posing a significant risk to patient safety. Many psychological factors are concerned with rising rates of errors among nurses. The implementation of proactive methods is a successful approach to mitigating medical errors within healthcare settings.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"15 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139001255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-14DOI: 10.9734/jpri/2023/v35i327467
Abeer Alanazi, Reema Albakheit, Hamad Alzahrani
Introduction: Cognitive decline is one of Parkinson's disease's (PD) non-motor symptoms that is most frequently observed. Patients with PD exhibit quick cognitive decline in a variety of cognitive domains, particularly in the areas of executive functions, attention, language, memory, and visuospatial abilities. The scope of PD patients with normal cognition (PD-NC) and its relationship to specific regions of the brain as shown by neuroimaging, have not received much attention in the literature. Objective: This review was to summarise the existing literature that explored cognitive performance in PD-NC using different neuroimaging techniques. Methods: A comprehensive search was conducted on PubMed and Web of Science databases. This review focused on papers that investigated neuroimaging and neuropsychological performance in patients with PD. A total of 17 articles have met the criteria. Results: The findings of this review were that executive functions appear to be the most critical cognitive domain to be damaged in PD-NC. Global cognitive ability was found to have insignificant decline overall between PD-NC and healthy controls (HC). Attention and executive functions were associated with the prefrontal cortex. Memory was mainly associated with hippocampal atrophy. Language was associated with cerebrospinal fluid and grey matter. Visuospatial ability was associated with the anterior cingulate cortex. Conclusion: This review illustrated that PD-NC seemed to experience different cognitive patterns and neuroanatomical changes compared with HC. These results suggested that PD-NC may develop specific cognitive impairments associated with specific brain regions. Therefore, it indicated that PD-NC may need to have specific treatments tailored to their needs.
导言：认知能力下降是帕金森病（PD）最常见的非运动症状之一。帕金森病患者在多个认知领域，尤其是在执行功能、注意力、语言、记忆力和视觉空间能力方面，都表现出快速的认知能力下降。神经影像学显示，认知正常的帕金森氏症患者（PD-NC）的范围及其与大脑特定区域的关系在文献中并未得到广泛关注。研究目的本综述旨在总结利用不同神经影像学技术探讨 PD-NC 认知表现的现有文献。研究方法在 PubMed 和 Web of Science 数据库中进行了全面检索。本综述侧重于研究帕金森病患者神经影像学和神经心理学表现的论文。共有 17 篇文章符合标准。研究结果综述结果表明，执行功能似乎是帕金森病-慢性阻塞性肺病患者受损最严重的认知领域。研究发现，总体认知能力的下降在帕金森综合症晚期患者和健康对照组（HC）之间并不明显。注意力和执行功能与前额叶皮层有关。记忆力主要与海马体萎缩有关。语言与脑脊液和灰质有关。视觉空间能力与前扣带回皮层有关。结论 本综述表明，与 HC 相比，PD-NC 似乎经历了不同的认知模式和神经解剖学变化。这些结果表明，PD-NC 可能会出现与特定脑区相关的特定认知障碍。因此，这表明 PD-NC 可能需要根据他们的需要进行特定的治疗。
{"title":"Neuroimaging and Neuropsychological Performance in Parkinson's Disease Patients with Normal Cognition: A Systematic Review","authors":"Abeer Alanazi, Reema Albakheit, Hamad Alzahrani","doi":"10.9734/jpri/2023/v35i327467","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i327467","url":null,"abstract":"Introduction: Cognitive decline is one of Parkinson's disease's (PD) non-motor symptoms that is most frequently observed. Patients with PD exhibit quick cognitive decline in a variety of cognitive domains, particularly in the areas of executive functions, attention, language, memory, and visuospatial abilities. The scope of PD patients with normal cognition (PD-NC) and its relationship to specific regions of the brain as shown by neuroimaging, have not received much attention in the literature. \u0000Objective: This review was to summarise the existing literature that explored cognitive performance in PD-NC using different neuroimaging techniques. \u0000Methods: A comprehensive search was conducted on PubMed and Web of Science databases. This review focused on papers that investigated neuroimaging and neuropsychological performance in patients with PD. A total of 17 articles have met the criteria. \u0000Results: The findings of this review were that executive functions appear to be the most critical cognitive domain to be damaged in PD-NC. Global cognitive ability was found to have insignificant decline overall between PD-NC and healthy controls (HC). Attention and executive functions were associated with the prefrontal cortex. Memory was mainly associated with hippocampal atrophy. Language was associated with cerebrospinal fluid and grey matter. Visuospatial ability was associated with the anterior cingulate cortex. \u0000Conclusion: This review illustrated that PD-NC seemed to experience different cognitive patterns and neuroanatomical changes compared with HC. These results suggested that PD-NC may develop specific cognitive impairments associated with specific brain regions. Therefore, it indicated that PD-NC may need to have specific treatments tailored to their needs.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"21 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139002594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-12DOI: 10.9734/jpri/2023/v35i317466
Madhura Titar, P. Sanyal, Shubha Joshi
Eye defects are surgically classified as evisceration, enucleation, and exenteration. It causes psychological trauma as an individual is visually and esthetically compromised. Eye defects can be restored with silicone or acrylic-based prosthesis. This is a case report of a patient with a customized ocular prosthesis where emphasis has been given to securing the iris shell during the laboratory process. A surface sealant has been used to provide glossiness to the prosthesis. The appearance of the patient was enhanced with the eye prosthesis.
{"title":"Fabrication of Customized Ocular Prosthesis using a Surface Sealant and Modified Laboratory Technique Using Stainless Steel Wire","authors":"Madhura Titar, P. Sanyal, Shubha Joshi","doi":"10.9734/jpri/2023/v35i317466","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i317466","url":null,"abstract":"Eye defects are surgically classified as evisceration, enucleation, and exenteration. It causes psychological trauma as an individual is visually and esthetically compromised. Eye defects can be restored with silicone or acrylic-based prosthesis. This is a case report of a patient with a customized ocular prosthesis where emphasis has been given to securing the iris shell during the laboratory process. A surface sealant has been used to provide glossiness to the prosthesis. The appearance of the patient was enhanced with the eye prosthesis.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"13 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-27DOI: 10.9734/jpri/2023/v35i317465
Hua Wang, Hui Ding
A novel and simple hyphenated method was applied for the screening of alkaloids in S. flavescens. The approach combined easy sample extraction with an ultra-high-performance liquid chromatography (UPLC) and a high-resolution mass spectrometry (HRMS) in the data-dependent acquisition (DDA) method. With the optimized chromatographic program, ten alkaloids were screened. Among them, matrine, oxymatrine, oxysophoridine, sophocarpine, and oxysophocarpine were identified and quantified. The other five alkaloids were identified with accurate m/z value in MS1 and product ions in MS2. The quantification method was validated with specificity, linearity, recovery, and precision. The LOD and LOQ were determined. In twelve batches of collected S. flavescens roots, the identified ten alkaloids were all observed. The oxymatrine was the most abundant component, and sophocarpine was the least abundant in these samples. This comprehensive method is a powerful tool for the biochemical and clinical research of S. flavescens. It can also be adopted in resource utilization and related medicine quality control.
{"title":"Screening of Alkaloids in Sophora Flavescens with Liquid Chromatography Tandem Data-Dependent Acquisition Mass Spectrometry","authors":"Hua Wang, Hui Ding","doi":"10.9734/jpri/2023/v35i317465","DOIUrl":"https://doi.org/10.9734/jpri/2023/v35i317465","url":null,"abstract":"A novel and simple hyphenated method was applied for the screening of alkaloids in S. flavescens. The approach combined easy sample extraction with an ultra-high-performance liquid chromatography (UPLC) and a high-resolution mass spectrometry (HRMS) in the data-dependent acquisition (DDA) method. With the optimized chromatographic program, ten alkaloids were screened. Among them, matrine, oxymatrine, oxysophoridine, sophocarpine, and oxysophocarpine were identified and quantified. The other five alkaloids were identified with accurate m/z value in MS1 and product ions in MS2. The quantification method was validated with specificity, linearity, recovery, and precision. The LOD and LOQ were determined. In twelve batches of collected S. flavescens roots, the identified ten alkaloids were all observed. The oxymatrine was the most abundant component, and sophocarpine was the least abundant in these samples. This comprehensive method is a powerful tool for the biochemical and clinical research of S. flavescens. It can also be adopted in resource utilization and related medicine quality control.","PeriodicalId":16718,"journal":{"name":"Journal of Pharmaceutical Research International","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139229027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：