Journal of Photochemistry and Photobiology A-chemistry最新文献

{"title":"Keggin-type Polyoxometalate-modified BiOI heterostructures for enhanced photocatalytic oxidation of hazardous organic pollutants","authors":"Nurseli Görener Erdem ,&nbsp;Nergiz Kanmaz ,&nbsp;Özlem Tuna ,&nbsp;Esra Bilgin Simsek","doi":"10.1016/j.jphotochem.2026.117056","DOIUrl":"10.1016/j.jphotochem.2026.117056","url":null,"abstract":"<div><div>Herein, we designed an interface-engineered heterojunction between bismuth oxyiodide (BiOI) and a Keggin-type polyoxometalate (H₃PW₁₂O₄₀, PW, POM) to accelerate interfacial charge transfer for dual photocatalytic functions: pollutant degradation and green H₂ evolution. The BiOI/PW composites were prepared by a hydrothermal route, and comprehensively characterized (XRD, SEM/EDS, XPS, BET, UV–vis DRS, PL, EIS, and Mott–Schottky). Morphological changes and elemental analysis from SEM/EDS together with XPS shifts and BET results, verified the integration of PW and robust its interfacial bonding with BiOI. The coupling of PW preserved the BiOI crystal phase while modulating its optoelectronic properties. EIS analysis revealed a reduced interfacial resistance consistent with faster carrier transport. Mott–Schottky analysis confirmed n-type behavior and the calculated band positions proposed direct <em>Z</em>-scheme charge migration across the interface. In the photocatalytic remediation tests, the optimized BiOI/PW (1: 4) achieved 84.7% degradation of crystal violet (CV) under visible light (vs 55.1% for BiOI) with a 2.72-fold higher apparent rate constant (0.00942 min⁻¹). Beyond CV, the composite exhibited notable versatility against structurally diverse dyes (e.g., 86.5% for allura red, 79.5% for sunset yellow) and pharmaceutical contaminants, such as doxycycline (82.8% vs 72.3% for BiOI), ciprofloxacin (58.1% vs 29.0%), and tetracycline (74.7% vs 70.0%), demonstrating broad-spectrum pollutant removal capability. Moreover, acute <em>Daphnia magna</em> bioassays revealed that the photocatalytic treatment markedly reduced ecotoxicity, with immobilization decreasing to below 50%Finally, the photocatalytic hydrogen evolution reached 6101 μmol g⁻¹ h⁻¹ for BiOI/PW (1, 4), 1.3-times greater than that of BiOI, underscoring the merit of POM-assisted interfacial design for multifunctional photocatalysis.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117056"},"PeriodicalIF":4.7,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excited-state isomerization and spectral reassignment of resveratrone induced by internal conversion","authors":"Mai-Ning Li ,&nbsp;Si-Ying Lu ,&nbsp;Ya-Jing Peng ,&nbsp;Yu Zhao ,&nbsp;Yu-Hui Liu ,&nbsp;Jun Gao ,&nbsp;Chaoyuan Zhu","doi":"10.1016/j.jphotochem.2026.117052","DOIUrl":"10.1016/j.jphotochem.2026.117052","url":null,"abstract":"<div><div>The excited-state isomerization of resveratrone (RES) is computationally investigated in order to reinterpret the spectral features associated with the excited-state proton transfer (ESPT) reaction dynamics in methanol solvents (MeOH). The calculations reveal that the <em>anti</em>-RES:MeOH is more stable than <em>syn</em>-RES:MeOH in the ground state (S₀). Upon excitation of <em>anti</em>-RES:MeOH to the first excited state (S₁), an ESPT reaction is taken place to generate the anionic species <em>anti</em>-1-anion:MeOH that undergoes an isomerization to <em>syn</em>-1-anion:MeOH due to a thermodynamically favorable energy pathway. Both anionic conformers contribute to the observed fluorescence emission. During the isomerization process, an intermediate state characterized by a twisted intramolecular charge transfer (TICT) configuration is encountered, which facilitates efficient non-radiative internal conversion (IC) owing to the small energy gap between the excited and ground states. Overall, hydrogen bonding plays a crucial role in enhancing the isomerization of both RES:MeOH in the S₀ state and 1-anion:MeOH in the S₁ state. These findings confirm the ESPT mechanism of RES:MeOH in methanol, involving the coexistence of radiative and non-radiative decay pathways. The experimentally observed absorption and emission spectra are successfully reassigned, leading to the proposal of a novel fluorescence mechanism for RES:MeOH in methanol.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117052"},"PeriodicalIF":4.7,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure-property relationships in D-π-D hole transport materials: Insights into conjugation, planarity, and interfacial charge dynamics","authors":"Yu Zhang ,&nbsp;Long Zhang ,&nbsp;Xuefei Pan ,&nbsp;Xueling Zhang ,&nbsp;Zifu Zang ,&nbsp;Yuanzuo Li","doi":"10.1016/j.jphotochem.2026.117051","DOIUrl":"10.1016/j.jphotochem.2026.117051","url":null,"abstract":"<div><div>We conducted a systematic investigation on the experimental hole transport material 4,8-bis(N-(4-(methylthio)phenyl)diphenylamino)-O-alkyl-BDT (BM) and three designed D-π-D type molecules (BM1, BP1, and A-BP1) using density functional theory and time-dependent density functional theory. The research content includes geometric structure, frontier molecular orbitals, stability, reorganization energy, excited state properties, hole mobility and interface characteristics. The research results show that compared with BM, the BM1, BP1, and A-BP1 are more compatible with that of the perovskite. Designed molecules exhibit two characteristic absorption peaks, and the charge transfer character was analyzed to reveal the electron-hole coherence in the D-π-D area and electron transfer direction from the two-sided diphenylamine donors to the π bridge. Analysis of the interface between molecules and perovskites shows BP1 and A-BP1 exhibit better interface character than BM, and A-BP1 possesses the highest hole mobility among all studied molecules. This study elucidates how the variation in the length of the π-bridge and the introduction of thiophene groups regulate the charge transport mechanism, providing a useful design guideline for high-performance HTMs in perovskite solar cells.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117051"},"PeriodicalIF":4.7,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of solvent polarity on excited-state proton transfer reaction for 2,5-diethyl-bis(benzoxazolyl)-2,6-dihydroxynaphthalene fluorophore: A theoretical study","authors":"Han Wang ,&nbsp;Jinfeng Zhao ,&nbsp;Jiahe Chen","doi":"10.1016/j.jphotochem.2026.117055","DOIUrl":"10.1016/j.jphotochem.2026.117055","url":null,"abstract":"<div><div>To address the theoretical gaps in the regulatory mechanism of excited-state double proton transfer (ESDPT) of 2,5-diethyl-bis(benzoxazolyl)-2,6-dihydroxynaphthalene (DBBD) – including the existence of ESDPT behaviors, reaction pathway, and how solvent polarity impacts intramolecular hydrogen bonds - this study selected four solvents with increasing polarity (heptane, toluene, tetrahydrofuran, and acetonitrile) to conduct relevant research. Findings demonstrated that in comparison to the ground state (S₀), DBBD in the first excited state (S₁) exhibited markedly strengthened intramolecular hydrogen bonds, evidenced by extended O<img>H bond lengths, shortened H<img>N bond lengths, and enlarged bond angles of Δ(O1H2N3) and Δ(O4H5N6); the stretching vibration frequency of O<img>H bonds in the S₁ state showed a notable redshift, and the redshift degree increased with solvent polarity, facilitating the breaking of O<img>H covalent bonds. Analysis of the core-valence bifurcation (CVB) index and bond critical point (BCP) parameter analysis further confirmed that hydrogen bonds in S₁ state were more robust than those in S₀ state, and solvent polarity could further amplify this effect. Frontier molecular orbital analysis revealed that the S₀ → S₂ transition of DBBD followed the HOMO-1 → LUMO transition (the ππ* type), and photoexcitation induced charge transfer from hydroxyl O atoms to N atoms, providing the core driving force for ESDPT reaction. Potential energy surface (PES) analysis suggested that the S₀ state possessed a high energy barrier for proton transfer, rendering excited-state intramolecular proton transfer (ESIPT) hardly feasible; in contrast, the S₁ state had prominent low-energy regions and low-energy barrier transition zones, and ESDPT proceeded in a stepwise pathway (DBBD → single-proton transfer state DBBD-PT1 → double-proton transfer state DBBD-PT2) with low energy barriers. With the increase of solvent polarity, the solvation effect more significantly stabilized the polar intermediate (DBBD-PT1) and product (DBBD-PT2) in the S₁ state, reduced the energy barriers of each ESDPT step, and improved product stability. This study clearly verifies the mechanism by which solvent polarity regulates the stepwise ESDPT of DBBD, providing a theoretical basis for understanding the environmental response mechanism of double proton transfer systems and offering guidance for the design of solvent polarity-responsive fluorescent materials.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117055"},"PeriodicalIF":4.7,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ultrasensitive Split-Aptasensor for L-selectin: Integrating nicking enzyme-assisted 3D DNA Walker with CRISPR-Cas12a signal amplification","authors":"Li Zhou ,&nbsp;Xianwei Jiao ,&nbsp;Yuting Zhang ,&nbsp;Changling Yan","doi":"10.1016/j.jphotochem.2026.117053","DOIUrl":"10.1016/j.jphotochem.2026.117053","url":null,"abstract":"<div><div>L-selectin, a leukocyte adhesion receptor, is essential in the early step of the adhesion cascade, facilitating the migration of leukocytes into surrounding tissues during inflammation and immune surveillance. Clinical studies have identified L-selectin as a prospective treatment option for many both acute and ongoing inflammatory conditions. Clarifying the cellular signaling pathways that function in the immediate vicinity of L-selectin may yield unique treatments tailored to certain cell types or illnesses. The study describes the development of a precise and sensitive fluorescence biosensor designed for the detection of L-selectin using a split aptamer specific to L-selectin. This biosensor utilizes nicking enzyme-assisted DNA walking together CRISPR-Cas12a for dual-signal multiplication. The calibration curve for L-selectin demonstrates a detection limit of 0.45 ng/mL, with an extensive linear range spanning from 10 to 1280 ng/mL. The fluorometric sensors effectively identified L-selectin in human blood samples, producing excellent outcomes. The fluorometric sensors effectively identified L-selectin in human blood samples, producing excellent outcomes. The original appearance not only validates the concept but also possesses substantial possibilities for identifying diverse targets.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117053"},"PeriodicalIF":4.7,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A-site doping modulates Mn2+ energy level splitting for green luminescence in Cs3MnBr5 perovskites under blue excitation and stacking solar cell application","authors":"Ru-Ping Wang ,&nbsp;Xiao-Song Zhang ,&nbsp;Xiu-Rong Yuan ,&nbsp;Xiao-Kai Gong ,&nbsp;Hai-Bo Ma ,&nbsp;Bao-Zeng Zhou ,&nbsp;Li-Na Kong ,&nbsp;Jian-Ping Xu ,&nbsp;Lan Li","doi":"10.1016/j.jphotochem.2026.117048","DOIUrl":"10.1016/j.jphotochem.2026.117048","url":null,"abstract":"<div><div>Due to their high carrier mobility, tunable bandgaps, narrow emission linewidths and solution-processability, metal halide perovskites demonstrate exceptional promise in photovoltaics, optoelectronics and photodetection. But the toxicity of lead has hindered its practical applications significantly. A series of lead-free perovskites materials have received great attention from researchers, there remains substantial scope for advancing research into the narrowband tunability of such lead-free perovskite materials compared to CsPbBr₃. Bromo‑manganese cesium perovskites can achieve red and green luminescence, but there are still unsatisfactory luminescence efficiency, poor stability, limited green light tunability, and the mechanism by which alkali metal ion doping affects the regulation of energy level splitting by the manganese crystal field remains unclear. This study prepares Cs₃MnBr₅ via thermal injection. A-site doping (partially substituting Cs with Na, K ions) preserves its crystal structure. Doping with Na⁺ and K⁺ enhances the luminescence intensity of the material and enables effective spectral modulation, while also providing insights into the underlying mechanism. Specifically, modifications to the lattice structure tune the electronic properties, induce splitting of the Mn²⁺ energy levels, and increase the splitting energy of the 3d orbitals. The energy required for the electronic transition from the ⁴T₁(G) state to the (Wang et al., 2024⁶⁾A₁(S) energy level increases, leading to the occurrence of a blue shift and achieving the spectral tunability within the green light range. Silicon solar cells exhibit enhanced power conversion efficiency (PCE) when undoped Cs₃MnBr₅ and Na/K-doped Cs₃MnBr₅ are employed as the down-conversion layer. Thus, this material exhibits broad application prospects in lighting, display technology, optoelectronic devices, biomedical.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117048"},"PeriodicalIF":4.7,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simulation-guided modulation of organic photothermal conversion based on pH-responsive molecular photorotation for photothermal antibacterial applications","authors":"Huajing Zhang,&nbsp;Yi Li,&nbsp;Weiqi Yu,&nbsp;Tong Zheng,&nbsp;Xiujun Han,&nbsp;Conghui Si,&nbsp;Mingzhi Wei,&nbsp;Shunwei Chen","doi":"10.1016/j.jphotochem.2026.117049","DOIUrl":"10.1016/j.jphotochem.2026.117049","url":null,"abstract":"<div><div>Stimulus-responsive photothermal materials hold great promise for precise and targeted biomedical applications, including tumor photothermal therapy and photothermal antibacterial treatment. In this work, a pH-sensitive small organic photothermal molecule (HNID) that features a C<img>N-bridged donor-acceptor (D-A) structure stabilized by an intramolecular OH···O hydrogen bond was designed by adopting a photorotation-driven non-radiative decay strategy, guided by both static theoretical calculations and excited-state dynamics simulations. This strategy is based on pH-controlled access to a non-radiative decay channel via a conical intersection (CI) resulting from photoinduced C<img>N rotation. Validated by experiments, HNID exhibits pH-sensitive photothermal conversion, achieving a remarkable two-fold enhancement in photothermal conversion efficiency (PTCE) from 16.8% (pH 7) to 50.8% (pH 10.5). Furthermore, HNID demonstrates significantly improved photothermal antibacterial performance under alkaline conditions compared to that in the neutral environment. This study offers molecular-level insights into the rational design of pH-responsive photothermal materials for relevant applications.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117049"},"PeriodicalIF":4.7,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel spectrofluorimetric method to determine warfarin sodium in serum, urine, and tablets using Eu3+-doxycycline optical sensor","authors":"Amal A. Mohamed","doi":"10.1016/j.jphotochem.2026.117034","DOIUrl":"10.1016/j.jphotochem.2026.117034","url":null,"abstract":"<div><div>A sensitive, simple, and selective spectrofluorimetric approach was created and validated to detect Warfarin sodium (WF) in serum, pharmaceutical, and urine samples. The method was based on utilizing a change in luminescence intensity of europium doxycycline (Eu³⁺-DOX) as an optical sensor. The WF can effectively quench the luminescence intensity of Eu³⁺-DOX in acetonitrile at λ_ex = 395 nm and in a buffered medium at pH 8.0. This quenching, particularly the distinctive peak at λ_em = 616.5 nm, is used to quantify WF in pharmaceutical tablets and biological samples. Under the optimum conditions, the concentration of WF can be determined within a dynamic range of (6.0 × 10⁻⁷-1.9 × 10⁻⁵) mol L⁻¹ and a high correlation coefficient (0.999). The limit of detection (LOD) is 1.86 × 10⁻⁷ mol L⁻¹ and the limit of quantification (LOQ) is 5.6 × 10⁻⁷ mol L⁻¹, respectively. Spectroscopic characterization, including emission and absorption spectra, validated the acquired sensor. Several properties validate the enhanced method, including linearity, precision, robustness, and accuracy.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117034"},"PeriodicalIF":4.7,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined photothermal effect with built-in electric field enhances tetracycline degradation: Mechanism and ecological risks","authors":"Rongyu Zhang ,&nbsp;Yibo Xin ,&nbsp;Qiaozhi Yan ,&nbsp;Xuemin Yin ,&nbsp;Xueying Wang ,&nbsp;Changyu Lu","doi":"10.1016/j.jphotochem.2026.117050","DOIUrl":"10.1016/j.jphotochem.2026.117050","url":null,"abstract":"<div><div>Photothermal-assisted photocatalysis and interfacial bonding have been validated as efficient strategies to modulate charge carrier transfer dynamics within heterojunctions, consequently facilitating the enhancement of photocatalytic performance of the catalysts. In this study, we produced a 0D/3D ZnFe₂O₄/ZnIn₂S₄ heterojunction exhibiting a “superposition-enhanced” photothermal effect. This structure effectively degrades tetracycline (TC) through photothermal-assisted photocatalysis. Density functional theory (DFT) calculations and temperature-controlled experimental analyses demonstrated that the photothermal effects, S-Zn-O bonding, facilitated the interfacial transport of photo-generated carriers. When exposed to visible light, the photothermally assisted photocatalytic system constructed using ZFO/ZIS achieved a degradation rate of 81.18% of TC in 110 min. The TOC removal rates of 3% ZFO/ZIS was 56.31%. Additionally, the ecological risk associated with TC degradation products was assessed using the Ecological Structure Activity Relationship (ECOSAR) model, and the results were further confirmed through a bean sprout cultivation experiment, which demonstrated that the TC degradation products posed a low environmental risk. Additionally, the heterojunction exhibited a low metal ion leaching rate. This research introduced an innovative and practical approach for designing and developing photocatalysts aimed at photothermal-assisted photocatalysis and the breakdown of organic pollutants.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117050"},"PeriodicalIF":4.7,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bis-(phenylselenide) based turn-on fluorescent probe for rapid, perceptible and selective detection of superoxide anion in human colon cancer cells","authors":"Snehal S. Salunkhe ,&nbsp;Divyesh S. Shelar ,&nbsp;Pratik P. Dhavan ,&nbsp;Ray J. Butcher ,&nbsp;Sudesh T. Manjare","doi":"10.1016/j.jphotochem.2026.117033","DOIUrl":"10.1016/j.jphotochem.2026.117033","url":null,"abstract":"<div><div>Superoxide anion is a type of reactive oxygen species (ROS) obtained by one-electron reduction of an oxygen molecule. It temporarily resides in the mitochondria before spreading throughout the cell and in human it regulates many signal transduction processes. Since increased levels of superoxide can cause permanent destruction to human bodies, the discovery of an effective method is significantly important for its selective and sensitive detection. This work explores a new “turn-on” fluorescence probe, Se-BODIPY-Se, which was synthesized and characterized by ¹H, ¹³C, ⁷⁷Se, ¹¹B, and ¹⁹F NMR spectroscopy, LCMS, and single-crystal XRD. The strategy of the probe was based on the photo-induced electron transfer (PET) mechanism between phenylselenide as an electron donor and BODIPY as an electron acceptor moiety. The fluorescence could be restored as a result of the termination of the PET process by the oxidation of selenium when treated with superoxide. The probe presented a high selectivity toward superoxide rather than other ROS, metal ions, biothiols, and amino acids, with a 63-fold marked fluorescence enhancement at 518 nm. The probe operates at physiological pH (7.4), achieving a detection limit down to 31 nM. Furthermore, it selectively detects superoxide anion in the HCT-116 cell line with a 7.4-fold increase in fluorescence intensity, indicating its potential application in live cancer cell imaging.</div></div>","PeriodicalId":16782,"journal":{"name":"Journal of Photochemistry and Photobiology A-chemistry","volume":"475 ","pages":"Article 117033"},"PeriodicalIF":4.7,"publicationDate":"2026-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}