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Ervebo (Ebola Zaire Vaccine, Live/rVSVΔG-ZEBOV-GP): The First Licensed Vaccine for the Prevention of Ebola Virus Disease Ervebo(埃博拉扎伊尔活疫苗/rVSVΔG-ZEBOV-GP):第一个获得许可的预防埃博拉病毒病的疫苗
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-08-14 DOI: 10.1177/8755122520950692
Chris Piszczatoski, J. Gums
Objective: To review the clinical data regarding the safety and efficacy of the Ervebo (Ebola Zaire vaccine, live/rVSVΔG-ZEBOV-GP) vaccine for the prevention of the Ebola virus disease. Data Sources: A literature search through PubMed, MEDLINE, and Cochrane Library was conducted for clinical trials published between January 2014 and June 2020 in the English language using the keywords Ervebo, rVSVΔG-ZEBOV, rVSVΔG-ZEBOV-GP, Ebola Zaire, and vaccine. Study Selection and Data Extraction: Articles were selected if they were related to the Food and Drug Administration (FDA) approval of Ervebo (Ebola Zaire vaccine, live/rVSVΔG-ZEBOV-GP) or provided novel data regarding this entity. Twelve articles noted in the FDA approval were chosen, along with 2 additional articles identified as providing novel information. Data Synthesis: The findings of the review show that Ervebo (Ebola Zaire vaccine, live/rVSVΔG-ZEBOV-GP) is a safe, immunogenic, and likely effective vaccine for the prevention of Ebola virus disease. Relevance to Patient Care and Clinical Practice: Ebola virus disease is highly infectious and often fatal. There have been multiple large outbreaks in the past 5 years, with no licensed treatments or vaccines. An effective vaccine could largely curtail current outbreaks and prevent further ones. Conclusion: The recent FDA approval of Ervebo (Ebola Zaire vaccine, live/rVSVΔG-ZEBOV-GP) offers the first approved vaccine for the prevention of Ebola virus disease. It has been shown to be safe, immunogenic, and likely effective for use in real-world applications for those at risk of contracting the disease.
目的:综述Ervebo(埃博拉扎伊尔活疫苗,rVSVΔG-ZEBOV-GP)疫苗预防埃博拉病毒病的安全性和有效性的临床资料。数据来源:通过PubMed、MEDLINE和Cochrane图书馆进行文献检索,检索2014年1月至2020年6月期间以英语发表的临床试验,检索关键词为Ervebo、rVSVΔG-ZEBOV、rVSVΔG-ZEBOV-GP、埃博拉扎伊尔和疫苗。研究选择和数据提取:选择与美国食品和药物管理局(FDA)批准的Ervebo(埃博拉扎伊尔疫苗,活疫苗/rVSVΔG-ZEBOV-GP)相关的文章,或提供有关该实体的新数据。FDA批准的12篇文章被选中,另外2篇文章被认为提供了新的信息。数据综合:审查结果表明,Ervebo(埃博拉扎伊尔活疫苗,rVSVΔG-ZEBOV-GP)是一种安全、具有免疫原性且可能有效的埃博拉病毒病预防疫苗。与病人护理和临床实践的相关性:埃博拉病毒病具有高度传染性,往往是致命的。在过去5年里发生了多次大规模疫情,没有获得许可的治疗方法或疫苗。一种有效的疫苗可以在很大程度上遏制目前的疫情,并防止进一步爆发。结论:最近FDA批准了Ervebo(埃博拉扎伊尔活疫苗,rVSVΔG-ZEBOV-GP),这是第一个被批准用于预防埃博拉病毒病的疫苗。它已被证明是安全的,免疫原性的,并且可能对那些有感染疾病风险的人在现实世界中的应用有效。
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引用次数: 12
Defining the Role of the Advanced Pharmacy Technician: Perspective Dissonance 定义高级药学技术人员的角色:视角失调
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-08-08 DOI: 10.1177/8755122520947637
Allison M. Dering-Anderson, Madeline Blaha, J. Neville
Background: Pharmacy technicians serve as pharmacist extenders. Attempts at advancing their practice have not been as rapid as the profession would prefer. We postulated that a barrier to this advancement is lack of agreement between pharmacists and technicians on how advancement should occur and on what it means. Objective: The objectives were to evaluate the differences in definitions and expectations of “technician advancement” between pharmacists and pharmacy technicians as potential impediments to advancement. Methods: Multimodal: An initial questionnaire for pharmacy technicians was collected during the American Association of Pharmacy Technicians Annual Convention to identify major topics for further survey. From those data, a survey was developed to ask pharmacists and pharmacy technicians about “technician advancement.” Surveys were provided to technicians in seminar settings; to members of the Nebraska Pharmacists Association; and via online platforms such as Facebook. Additionally, face-to-face targeted interviews were conducted with pharmacy technicians attending American Association of Pharmacy Technicians conventions and with the pharmacy technician and pharmacist leaders at the Nebraska Pharmacists Association. Results: Responses show that pharmacists’ expectations for advancing the practice of pharmacy technicians and the expectations of the technicians themselves vary widely. A notable finding is that 96% of all technicians responding see technician payment as a significant issue in advancement, while less than 4% of pharmacists commented on rate of pay. Conclusion: While both pharmacists and pharmacy technicians are hopeful for pharmacy technician role advancement, there is substantial disagreement about the definition of advancement that may be a barrier to the process.
背景:药学技术人员是药剂师的延伸者。推进他们的实践的努力并没有像业内人士所希望的那样迅速。我们假设这种进步的障碍是药剂师和技术人员之间缺乏关于进步应该如何发生以及它意味着什么的协议。目的:评价药师和药学技术人员对“技术人员晋升”的定义和期望的差异。方法:多模式:在美国药学技术人员协会年会上收集药学技术人员的初步问卷,以确定进一步调查的主要主题。根据这些数据,研究人员开展了一项调查,询问药剂师和药学技术人员关于“技术进步”的问题。在讨论会中向技术人员提供了调查;内布拉斯加州药剂师协会会员;以及通过Facebook等在线平台。此外,对参加美国药学技术人员协会会议的药学技术人员以及内布拉斯加州药剂师协会的药学技术人员和药剂师领导进行了面对面的有针对性的访谈。结果:调查结果显示,药师对推进药学技术人员实践的期望与药学技术人员自身的期望差异较大。一个值得注意的发现是,96%的技术人员认为技术人员的薪酬是晋升的重要问题,而不到4%的药剂师对薪酬率发表了评论。结论:药师和药学技术人员都对药学技术人员角色提升抱有希望,但对角色提升的定义存在重大分歧,这可能成为阻碍药学技术人员角色提升的障碍。
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引用次数: 0
Evaluation of the Safety and Efficacy of Metformin Use in Hospitalized, Non–Critically Ill Patients 二甲双胍在住院非危重患者中的安全性和有效性评价
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-03-13 DOI: 10.1177/8755122520911689
Tahnia Alauddin, Sarah E. Petite
Background: Contraindications and precautions to metformin have limited inpatient use, and limited evidence exists evaluating metformin in hospitalized patients. Objective: This study aimed to determine the safety and efficacy of inpatient metformin use. Methods: This study was an observational, retrospective, cohort study at an academic medical center between June 1, 2016, and May 31, 2018. Hospitalized adults with type 2 diabetes mellitus receiving at least 1 metformin dose were included. The primary endpoint was to identify hospitalized patients using metformin with at least 1 contraindication or precautionary warning against use. Secondary endpoints included assessing metformin efficacy with glycemic control, characterizing adverse outcomes of inpatient metformin, and comparing the efficacy of metformin-containing regimens. Results: Two hundred patients were included. There were 126 incidences of potentially unsafe use identified in 111 patients (55.5%). The most common reasons were age ≥65 years (47%), heart failure diagnosis (7.5%), and metformin within 48 hours of contrast (6%). Metformin was contraindicated in 2 patients (1%) with an estimated glomerular filtration rate ≤30 mL/min/1.73 m2. The overall median daily blood glucose was 146 mg/dL (interquartile range [IQR] = 122-181). Patients were divided into 3 groups: metformin monotherapy, metformin plus oral antihyperglycemic therapy, and metformin plus insulin. The median daily blood glucoses were 129 mg/dL (IQR = 110-152), 154 mg/dL (IQR = 133-178), and 174 mg/dL (IQR = 142-203; P < .001), respectively. Two patients (1%) developed acute kidney injury, and no patients developed lactic acidosis. Conclusions: Metformin was associated with goal glycemic levels in hospitalized patients with no adverse outcomes. These results suggest the potential for metformin use in hospitalized, non–critically ill patients.
背景:二甲双胍的禁忌症和注意事项限制了住院患者的使用,并且评估二甲双胍在住院患者中的应用证据有限。目的:本研究旨在确定住院患者使用二甲双胍的安全性和有效性。方法:本研究是一项观察性、回顾性、队列研究,于2016年6月1日至2018年5月31日在某学术医学中心进行。接受至少1剂二甲双胍治疗的住院成人2型糖尿病患者被纳入研究。主要终点是确定住院患者使用二甲双胍至少有一个禁忌症或预防性警告。次要终点包括评估二甲双胍与血糖控制的疗效,表征住院二甲双胍的不良结局,以及比较含二甲双胍方案的疗效。结果:纳入200例患者。111例患者中发现126例潜在不安全用药(55.5%)。最常见的原因是年龄≥65岁(47%)、心衰诊断(7.5%)和48小时内使用二甲双胍(6%)。2例(1%)估计肾小球滤过率≤30ml /min/1.73 m2的患者禁用二甲双胍。总体每日血糖中位数为146 mg/dL(四分位数范围[IQR] = 122-181)。患者分为3组:单用二甲双胍治疗、口服二甲双胍联合降糖治疗、二甲双胍联合胰岛素治疗。中位日血糖分别为129 mg/dL (IQR = 110-152)、154 mg/dL (IQR = 133-178)和174 mg/dL (IQR = 142-203;P < 0.001)。2例(1%)患者发生急性肾损伤,无患者发生乳酸酸中毒。结论:二甲双胍与住院患者的目标血糖水平相关,且无不良结局。这些结果提示二甲双胍在住院非危重患者中的应用潜力。
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引用次数: 1
The Efficacy of Flow Restrictors on Children’s Liquid Acetaminophen Products 流量限制器对儿童液体对乙酰氨基酚产品的影响
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-03-13 DOI: 10.1177/8755122520911208
Jacob Budnitz, Stephanie L Hon, J. Punzi
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引用次数: 1
Initiation of Emicizumab Therapy in an Adult Patient With Hemophilia A With Inhibitors and Associated Drug Cost Savings Emicizumab治疗A型血友病成人患者的抑制剂和相关药物成本节约
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-02-21 DOI: 10.1177/8755122520906291
Adam Root, Robert D. Raiff, T. Ortel, Kimberly L. Hodulik
Objective: To report the utilization of emicizumab in a patient with severe hemophilia A with inducible inhibitors and the reduction of drug costs related to decreased on-demand recombinant factor VIIa use. Case Summary: A 65-year-old African American man with established hemophilia A with an inducible factor VIII inhibitor presented with a bleeding hematoma from the right posterior thigh. The patient was historically managed on frequent administration of recombinant factor VIIa to achieve hemostasis and was started on every 2-hour dosing during this admission. Emicizumab, a new therapy for hemophilia A, became available during this admission, and the patient discontinued recombinant factor VIIa and transitioned to weekly emicizumab injections. The patient did not require any recombinant factor VIIa during the following 12 months resulting in substantial drug cost savings. Discussion: After initiation of emicizumab therapy, the patient no longer required on-demand treatment with recombinant factor VIIa for bleeds. Through this reduction in recombinant factor VIIa, there was a large decrease in inpatient drug costs and inpatient admissions for bleeding events. Conclusion: The potential reduction in drug costs and inpatient admissions should be considered when determining if emicizumab therapy is appropriate for hemophilia A patients with inhibitors. Further research is needed to confirm that continued long-term use of emicizumab remains associated with a reduction in on-demand treatment.
目的:报道emicizumab在1例有诱导抑制剂的严重a型血友病患者中的应用,以及与减少按需重组因子VIIa使用相关的药物成本降低。病例总结:一名65岁非裔美国男性血友病A与诱导因子VIII抑制剂表现为右后大腿出血血肿。患者既往经常给予重组VIIa因子以实现止血,并在入院期间每2小时给药一次。Emicizumab是一种治疗血友病a的新疗法,在此入院期间,患者停用重组因子VIIa,并过渡到每周注射Emicizumab。在接下来的12个月里,患者不需要任何重组VIIa因子,从而节省了大量的药物成本。讨论:在开始emicizumab治疗后,患者不再需要按需使用重组VIIa因子治疗出血。通过重组因子VIIa的减少,住院药物费用和出血事件住院率大幅下降。结论:在确定半蜜珠单抗治疗是否适合使用抑制剂的A型血友病患者时,应考虑药物成本和住院率的潜在降低。需要进一步的研究来证实持续长期使用emicizumab仍然与按需治疗的减少有关。
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引用次数: 0
The Impact of Face-to-Face Pharmacist Transitional Care Management Visits on Medication-Related Problems 面对面药师过渡性护理管理访视对药物相关问题的影响
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2020-02-17 DOI: 10.1177/8755122520905582
Bianca Mayzel, Sandra S. Axtell, Carolyn M. Richardson, N. Link
Background: Studies are needed to evaluate medication-related problems (MRPs) to assess the effect of a pharmacist on managing medications postdischarge. Objective: To assess the ability of pharmacist-led medication review and reconciliation to reduce the number of MRPs found in transitional care medicine (TCM) visits, leading to medication optimization. Methods: This study involved a retrospective chart review of standard TCM procedure at a family/internal medicine clinic and a prospective, team-based TCM visit in the same clinic. Inclusion criteria included patients discharged from any hospital within our institution and seen in the clinic. The primary outcome was the difference in the proportion of MRPs found between the prospective and retrospective groups. Secondary outcomes included the number and specific type of MRPs found, classified by the Pharmaceutical Care Network Europe tool, and further subdivided by patient aware or unaware of MRP, only in the prospective group, as well as 30-day readmission rate. Results: Patients in the prospective group (n = 50) had an average age of 67.9 years versus 65.5 years in the retrospective group (n = 50). Four times as many patients in the prospective group were found to have MRPs than the retrospective group. The most common MRP was due to a patient-related factor, meaning the cause is related to a patient’s behavior. Patients were unaware of the MRP in a majority of these cases. Thirty-day readmission rate did not differ between the groups. Conclusion: Team-based TCM visits that included a pharmacist-led medication reconciliation uncovered more MRPs than patients who did not have a pharmacist perform a medication reconciliation.
背景:需要对药物相关问题(MRPs)进行研究,以评估药师对出院后药物管理的效果。目的:评估药师主导的药物审查和调解的能力,以减少在转诊中医(TCM)就诊中发现的mrp数量,从而优化用药。方法:本研究包括对家庭/内科诊所的标准中医程序和同一诊所的前瞻性、基于团队的中医就诊进行回顾性图表回顾。纳入标准包括从我们机构内任何一家医院出院并在诊所就诊的患者。主要结果是在前瞻性组和回顾性组之间发现的mrp比例的差异。次要结局包括发现MRP的数量和具体类型,由欧洲药物护理网络工具分类,并进一步细分为患者知道或不知道MRP,仅在前瞻性组中,以及30天再入院率。结果:前瞻性组(n = 50)患者的平均年龄为67.9岁,而回顾性组(n = 50)的平均年龄为65.5岁。在前瞻性组中发现mrp的患者是回顾性组的四倍。最常见的MRP是由患者相关因素引起的,这意味着原因与患者的行为有关。在大多数病例中,患者不知道MRP。30天再入院率在两组之间没有差异。结论:以团队为基础的中医就诊,包括药剂师主导的药物和解,比没有药剂师进行药物和解的患者发现更多的mrp。
{"title":"The Impact of Face-to-Face Pharmacist Transitional Care Management Visits on Medication-Related Problems","authors":"Bianca Mayzel, Sandra S. Axtell, Carolyn M. Richardson, N. Link","doi":"10.1177/8755122520905582","DOIUrl":"https://doi.org/10.1177/8755122520905582","url":null,"abstract":"Background: Studies are needed to evaluate medication-related problems (MRPs) to assess the effect of a pharmacist on managing medications postdischarge. Objective: To assess the ability of pharmacist-led medication review and reconciliation to reduce the number of MRPs found in transitional care medicine (TCM) visits, leading to medication optimization. Methods: This study involved a retrospective chart review of standard TCM procedure at a family/internal medicine clinic and a prospective, team-based TCM visit in the same clinic. Inclusion criteria included patients discharged from any hospital within our institution and seen in the clinic. The primary outcome was the difference in the proportion of MRPs found between the prospective and retrospective groups. Secondary outcomes included the number and specific type of MRPs found, classified by the Pharmaceutical Care Network Europe tool, and further subdivided by patient aware or unaware of MRP, only in the prospective group, as well as 30-day readmission rate. Results: Patients in the prospective group (n = 50) had an average age of 67.9 years versus 65.5 years in the retrospective group (n = 50). Four times as many patients in the prospective group were found to have MRPs than the retrospective group. The most common MRP was due to a patient-related factor, meaning the cause is related to a patient’s behavior. Patients were unaware of the MRP in a majority of these cases. Thirty-day readmission rate did not differ between the groups. Conclusion: Team-based TCM visits that included a pharmacist-led medication reconciliation uncovered more MRPs than patients who did not have a pharmacist perform a medication reconciliation.","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"64 1","pages":"101 - 95"},"PeriodicalIF":1.0,"publicationDate":"2020-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84149533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Reviewer Acknowledgment 评论家承认
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2019-12-22 DOI: 10.1177/8755122519891261
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引用次数: 0
Reviewer Acknowledgment 评论家承认
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2018-12-30 DOI: 10.1177/8755122518814935
Ahmet Emre Eyler, Rachel F. Faley, Jan M. Kim, Myeong Gyu Knockel, Brooke Stultz, Jeremy Swanson, Joseph M. Takieddine, S. Tanoshima, Reo Tawil, Samah Terrell, Jamie M. Thiboutot
Abeyta, Agnieszka Ackerbauer, Kimberly Adams, Alex Adeola, Mobolaji Akers, Julie Alalawi, Mai Allen, Bryan Alvarez-Risco, Aldo Anders, Stephanie Anderson, Shawn D. Asal, Nicole Bain, Kevin Baker, Michelle Bandy, Veronica T. Barenholtz Levy, Hedva Barros, Michael C. Bishop, Bryan Black, Robin Boisvert, Louis Bright, David Brown, Jacob Bruce, Susan Buchman, Christina Buckel, Whitney Burgess, Sarah Burghardt, Kyle Burka, Abigail Byerly, Wesley Bystrak, Tamara Carter, Chris Cates, Marshall E. Childs-Kean, Lindsey Chiu, Ada Chong, Christopher Colmenares, Evan Colucci, Vincent J. Conway, Stephanie L. Cook, Elizabeth Covington, Elizabeth Cowart, Kevin Coz-Yataco, Angel Dash, Ranjeet D’Astoli, Joseph Dawwas, Ghadeer Dean, Stacey R. Deen, Beth Deming, Paulina Dharia, Sheetal Diec, Sandy DiScala, Sandra Ditch, Kristen Dougherty, John A. Eaves, Shannon Eljaaly, Khalid Enderby, Cher Eskazan, Ahmet Emre Eyler, Rachel F. Faley, Brian Farinola, Nicholas Felix, Daniel Fleming, James Gibson, Mara Gónzalez Álvarez, Isabel Gören, Jessica Hashida, Tohru Hashmi, Furqan Hellenga, Nadia Hockman, Rebecca Haynes Hoke, Kathleen House, Naomi Huang, Yen-Ming Hughes, Jonathan Jackson, Kristy Janzen, Kristin Jellinek-Cohen, Samantha P. Johannesmeyer, Herman Kane, Brenna Keeshin, Susana Keresztes, Jan M. Kim, Myeong Gyu Knockel, Laura Kopcza, Kathleen B. Krantz, Erica Krichbaum, Michelle Krikorian, Susan A. Leffler, Michaela Leo, Andrea Levine, Alexander Liao, Siyun Lilliston, Andrea Michelle Liu, Wenxi Lyles, Adraine Lawrence MacDonald, Nancy C. Macedo, Kelly Mahan, Rebecca Malone, Patrick Mathew, Sheryl Mercuro, Nicholas Merrey, Jessica Molino, Suzanne Mospan, Cortney Muir, Justin Okeahialam, Basil Patel, Hansita Pattie, Stacey Baker Pektezel, Mehmet Petite, Sarah Powers, Mary Redfern, Roberta Rein, Leanne Rhalimi, Mounir Rose, Christina Rosselli, Jennifer Russak, Edward Salerno, David Scherrer, Leigh Seed, Sheila Selvi-Sabater, Pablo Skordallos, Sebastian Slugocki, Malgorzata Smith, Susan Snyder, Scott Spence, Nathan A. Spray, Jeffery Steinberg, Michael Steiner, Chris 814935 PMTXXX10.1177/8755122518814935Journal of Pharmacy Technology other2018
{"title":"Reviewer Acknowledgment","authors":"Ahmet Emre Eyler, Rachel F. Faley, Jan M. Kim, Myeong Gyu Knockel, Brooke Stultz, Jeremy Swanson, Joseph M. Takieddine, S. Tanoshima, Reo Tawil, Samah Terrell, Jamie M. Thiboutot","doi":"10.1177/8755122518814935","DOIUrl":"https://doi.org/10.1177/8755122518814935","url":null,"abstract":"Abeyta, Agnieszka Ackerbauer, Kimberly Adams, Alex Adeola, Mobolaji Akers, Julie Alalawi, Mai Allen, Bryan Alvarez-Risco, Aldo Anders, Stephanie Anderson, Shawn D. Asal, Nicole Bain, Kevin Baker, Michelle Bandy, Veronica T. Barenholtz Levy, Hedva Barros, Michael C. Bishop, Bryan Black, Robin Boisvert, Louis Bright, David Brown, Jacob Bruce, Susan Buchman, Christina Buckel, Whitney Burgess, Sarah Burghardt, Kyle Burka, Abigail Byerly, Wesley Bystrak, Tamara Carter, Chris Cates, Marshall E. Childs-Kean, Lindsey Chiu, Ada Chong, Christopher Colmenares, Evan Colucci, Vincent J. Conway, Stephanie L. Cook, Elizabeth Covington, Elizabeth Cowart, Kevin Coz-Yataco, Angel Dash, Ranjeet D’Astoli, Joseph Dawwas, Ghadeer Dean, Stacey R. Deen, Beth Deming, Paulina Dharia, Sheetal Diec, Sandy DiScala, Sandra Ditch, Kristen Dougherty, John A. Eaves, Shannon Eljaaly, Khalid Enderby, Cher Eskazan, Ahmet Emre Eyler, Rachel F. Faley, Brian Farinola, Nicholas Felix, Daniel Fleming, James Gibson, Mara Gónzalez Álvarez, Isabel Gören, Jessica Hashida, Tohru Hashmi, Furqan Hellenga, Nadia Hockman, Rebecca Haynes Hoke, Kathleen House, Naomi Huang, Yen-Ming Hughes, Jonathan Jackson, Kristy Janzen, Kristin Jellinek-Cohen, Samantha P. Johannesmeyer, Herman Kane, Brenna Keeshin, Susana Keresztes, Jan M. Kim, Myeong Gyu Knockel, Laura Kopcza, Kathleen B. Krantz, Erica Krichbaum, Michelle Krikorian, Susan A. Leffler, Michaela Leo, Andrea Levine, Alexander Liao, Siyun Lilliston, Andrea Michelle Liu, Wenxi Lyles, Adraine Lawrence MacDonald, Nancy C. Macedo, Kelly Mahan, Rebecca Malone, Patrick Mathew, Sheryl Mercuro, Nicholas Merrey, Jessica Molino, Suzanne Mospan, Cortney Muir, Justin Okeahialam, Basil Patel, Hansita Pattie, Stacey Baker Pektezel, Mehmet Petite, Sarah Powers, Mary Redfern, Roberta Rein, Leanne Rhalimi, Mounir Rose, Christina Rosselli, Jennifer Russak, Edward Salerno, David Scherrer, Leigh Seed, Sheila Selvi-Sabater, Pablo Skordallos, Sebastian Slugocki, Malgorzata Smith, Susan Snyder, Scott Spence, Nathan A. Spray, Jeffery Steinberg, Michael Steiner, Chris 814935 PMTXXX10.1177/8755122518814935Journal of Pharmacy Technology other2018","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"2013 1","pages":"45 - 46"},"PeriodicalIF":1.0,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82697409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewer Acknowledgment 评论家承认
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2018-02-01 DOI: 10.1177/8755122517744031
Sakra Saleh, Bandy, L. Jason, Barenholtz Levy, Hedva, Barros, C. Michael, Battaglia, Laura, Kopcza
Abazia, Daniel Adams, Alex Akins, Ronda Al-Shaer, Mohammad Ali, Saadia Alkim, Huseyin Alvarez-Risco, Aldo Bahmaid, Reem Balhareth, Sakra Saleh Bandy, Jason L. Barenholtz Levy, Hedva Barros, Michael C. Battaglia, Jessica N. Bergan, Jennifer Bernknopf, Allison Bonanno, Christina Borja-Hart, Nancy Bork, Sara Brenner, Allison C. Bright, David Britton, Emily Brown, Sherrill J. Bucher, Kasey Burgess, Sarah Burnett, Yvonne Byrnes, Holly Cates, Marshall E. Chaddha, Ashish Chong, Christopher Clements, Jennifer N. Cocchio, Craig Coletti, Daniel Cox, Laura McIntyre Cristofaro, Lisa Dault, Roxanne DeRemer, David DiMondi, Vincent Dunham, Marissa Dunn, Deanna Dutta Choudhury, Shubhasree Ellis, Mary Elsey, Rachel Evans, Shelby Eyler, Rachel F. Faley, Brian Fink, Joseph Fox, Lanae Fuji, Kevin Gillette, Michael Golchin, Negar Goldshtein, Inbal Hahn, Lindsay Hale, Charity Hansen, Kevin Hawks, Kelly Hein, Bradley E. Hill, Jordan Hohmeier, Kenneth Hui, Adrian Hutchison, Lisa Comer Jensen, Leon K. Jordan, Melanie Joseph, Merlyn Justis, Leanne Kang-Birken, Sunghe Lena Kaur, Upinder Keresztes, Jan M. Kliethermes, Mary Ann Knockel, Laura Kopcza, Kathleen B. Kouladjian O’Donnell, Lisa Krajewski, Kristin Lacher, Barbara Laskey, Dayne LaVance, Anne Leonard, Charles Li Ying, Huang Lin, Shin Yi Ling, Hua Lukasiewicz, Ronald H. Manzor Mitrzyk, Beatriz McCoy, Cheryl Merino-Bohórquez, Vicente Morin, Lucas Mruk, Allison Munsour, Emad Eldin Newman, Luke Papadopoulos, Nikolaos Park, Jiehye Patanwala, Asad Pegram, Angela Pervanas, Helen Peterson, Tim Pon, Tiffany Powers, Mary Priano, James Quinn, Andrea Renfro, Chelsea Rice, Kathryn Roberts, Gregory Robinson, Renee F. Rose, Adam J. Rosselli, Jennifer Sargin, Gokhan Scott, James D. Seed, Sheila Serlemitsos-Day, Maritsa Shea, Peter Shin, Maria Sirois, Caroline Skinner, Brian Spooner, Linda M. Stading, Julie A. Stevens, Brooke Stewart, Kyana Stultz, Jeremy Sullivan, Karyn Takieddine, Sheila Tawil, Samah Thompson, Alyssa Thornton, James Thurston, Maria Traeger, Jessica 744031 PMTXXX10.1177/8755122517744031Journal of Pharmacy Technology research-article2017
Abazia,丹尼尔·亚历克斯·亚当斯Akins任务Al-Shaer,穆罕默德·阿里,Saadia Alkim, Huseyin Alvarez-Risco, Aldo Bahmaid, Reem Balhareth Sakra萨利赫武器、杰森·L . Barenholtz Levy,巴罗斯,迈克尔·C .战斗,Jessica Hedva皮娜Bergan号,Jennifer Bernknopf,艾莉森,Christina Borja-Hart,南希的贡献,莎拉·布伦纳艾莉森,C .布莱特,大卫·艾米丽·布朗,Sherrill J . Bucher, Kasey伯吉斯,莎拉·马歇尔Burnett, Yvonne Byrnes,霍莉Cates Chaddha、克里斯托弗·克莱门茨Ashish Chong,,Jennifer Cocchio号,克雷格·Coletti,丹尼尔·考克斯,劳拉McIntyre Cristofaro, Lisa Dault, Roxanne DeRemer、大卫·DiMondi玛丽莎•邓恩,Deanna Vincent Dunham Dutta乔杜里Shubhasree Ellis,玛丽Elsey,蕾切尔·埃文斯,Eyler谢尔比,蕾切尔·F . Faley Brian Fink、约瑟夫·福克斯、Lanae富士、凯文·吉列迈克尔·Golchin剥夺他们Goldshtein,哈恩Inbal,林赛Hale,接生婆慈善Hansen,凯文·凯利Hawks, Hein, Bradley E . Hill,肯尼斯·乔丹Hohmeier詹森Adrian和记黄埔,Lisa Comer,杨辉Leon Merlyn Justis,梅勒妮·约瑟夫·K . Jordan, Leanne Kang-Birken,莉娜Sunghe Kaur, Upinder Keresztes, Jan M . Kliethermes, Mary Ann Knockel劳拉Kopcza、凯瑟琳·B . Kouladjian o ' donnell, Lisa Krajewski, Kristin Lacher,芭芭拉·Laskey, Dayne LaVance,安妮·伦纳德·查尔斯,李英,Huang Lukasiewicz Lin) Shin猫扑Ling,华,罗纳德·H . Manzor Mitrzyk, Beatriz McCoy,谢丽尔Merino-Bohórquez Vicente Morin, Lucas Mruk, Allison Munsour Emad Eldin Newman, Luke Nikolaos朴槿惠,帕帕佐普洛斯Jiehye Patanwala阿萨德Pegram,安吉拉Pervanas、海伦·彼得森,Tim在蒂鲍尔斯、玛丽Priano、詹姆斯·梅特·奎因,安德里亚·Renfro切尔西·凯瑟琳·康多莉扎•赖斯·罗伯茨(Renee ghert F . Rose,格雷戈里·罗宾逊(Mary Robinson)亚当·J . Rosselli,詹妮弗·萨金Gokhan斯科特先生,詹姆斯·D . Seed, Sheila Serlemitsos-Day, cbc Shea,彼得·斯金纳Shin玛丽亚·卡洛琳·Sirois Brian Spooner, Linda M . Stading朱莉。史蒂文斯,布鲁克·斯图尔特、Kyana Stultz,杰里米·沙利文,Karyn Takieddine Sheila Tawil、Samah汤普森Alyssa Thornton, James Thurston, Maria Traeger, Jessica 744040pmtxxx10
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引用次数: 0
Multimorbidity and Polypharmacy in Family Medicine Residency Practices 家庭医学住院医师实践中的多病多药
IF 1 Q4 PHARMACOLOGY & PHARMACY Pub Date : 2017-08-11 DOI: 10.1177/8755122517725327
Kenya Ie, Maria A. Felton, S. Springer, Stephen A. Wilson, S. Albert
Background: Prescription-related problems among older adults have been of great interest. However, few data are available regarding the prevalence of these problems in US family medicine residency practices (FMRPs). Objective: The aim of this research was to examine the prevalence of multimorbidity, polypharmacy, and potentially inappropriate medications (PIMs) use among older adults who visited 5 FMRPs more than once a year. Methods: A cross-sectional hospital record review for patients 65 years or older who visited 1 of the 5 university-affiliated FMRPs at least twice during January 1 to December 31, 2014, was conducted. The prevalence of multimorbidity (24 chronic index conditions), polypharmacy, and PIMs use was examined. Results: A total of 1084 patients were included in the analyses. The most common chronic conditions were hypertension (87.8%), hyperlipidemia (69.7%), and osteoarthritis (56.1%). The mean number of chronic conditions was 5.3 (SD 2.6). The prevalence of multimorbidity (≥2 chronic conditions) was 95.6%. Among these multimorbid older adults (N = 1036), the mean number of medication orders was 9.04 (SD 4.36) and 1.57 (SD 0.92) for PIMs, 86.1% met polypharmacy standards (≥5 medications), and 33.4% were prescribed one or more PIMs. The proportion of patients with fewer prescriptions at the last visit was 45.4% in the polypharmacy group and 38.0% in the PIMs group. Conclusion: Our results suggest a high level of morbidity and complexity among older adults receiving care in FMRPs. Improving the continuity of care as well as promoting interdisciplinary collaboration would have potential to reduce these prescription-related problems. Further research and education to address polypharmacy and PIMs among this population at FMRPs are required.
背景:老年人处方相关问题已引起人们极大的兴趣。然而,关于这些问题在美国家庭医学住院医师实践(FMRPs)中普遍存在的数据很少。目的:本研究的目的是检查每年访问5个以上fmrp的老年人中多病、多药和潜在不适当药物(PIMs)使用的患病率。方法:对2014年1月1日至12月31日期间至少两次访问5所大学附属fmrp中的1所的65岁及以上患者进行横断面医院记录回顾。多重疾病(24种慢性指标疾病)、多重用药和pim使用的患病率进行了检查。结果:共纳入1084例患者。最常见的慢性疾病是高血压(87.8%)、高脂血症(69.7%)和骨关节炎(56.1%)。慢性疾病的平均数量为5.3 (SD 2.6)。多病(≥2种慢性病)患病率为95.6%。在这些多病老年人(N = 1036)中,PIMs的平均用药单次为9.04次(SD 4.36)和1.57次(SD 0.92), 86.1%符合多药标准(≥5种药物),33.4%服用一种或多种PIMs。最后一次就诊时处方较少的比例,综合用药组为45.4%,综合用药组为38.0%。结论:我们的研究结果表明,在fmrp接受护理的老年人中,发病率和复杂性都很高。改善护理的连续性以及促进跨学科合作将有可能减少这些与处方有关的问题。需要进一步的研究和教育来解决FMRPs人群中的多药和pim问题。
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引用次数: 4
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Journal of Pharmacy Technology
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