首页 > 最新文献

JOURNAL OF SCIENTIFIC RESEARCH最新文献

英文 中文
Design of Experimental Lab Scale Vertical Mass Flow Type Bioreactor for Bioethanol Production by Co-Culture Strategy from Cassava Waste 立式质量流型木薯废弃物共培养生物乙醇反应器的设计
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59095
R. Prasad, C. Jijina, A. Akhila, T. Johnson, S. Ajayan
Due to a surge in demand and cost, there is a requirement for alternative energy sources by devising strategies for the efficient production of biofuels. Immobilized microbial systems for the conversion of biomass to fuels have become progressively important. Cassava (Manihot esculentum) processing waste, a massive byproduct of starch processing is utilized in this work for bioethanol production. This study was an attempt to design and develop an experimental lab-scale Vertical Mass-Flow type Bioreactor (VMFB) demarcated into aerobic and anaerobic zones to produce bioethanol. The upper aerobic zone was meant for saccharification and the lower anaerobic zone for fermentation, the technique is called Simultaneous Saccharification and Fermentation (SSF). The feasibility of co-immobilizing saccharification strains (A. awamori and D. bruxellensis) and fermentation strains (Z. mobilis) for bioethanol production through SSF from cassava agro-waste were tested. Polyurethane foam was used in the aerobic reaction zone and calcium-alginate beads immobilized microorganisms in the anaerobic reaction zone were employed as carriers for the immobilization. The main objective of this study was to understand the usability of agricultural waste, especially cassava processing waste as raw material for bioethanol production, using SSF technology a concentration of 8 % w/w ethanol was obtained.
由于需求和成本的激增,需要通过制定有效生产生物燃料的战略来替代能源。将生物质转化为燃料的固定化微生物系统已变得越来越重要。木薯(Manihot esculentum)加工废料是淀粉加工的大量副产品,在这项工作中用于生产生物乙醇。本研究旨在设计和开发一个实验室规模的垂直质量流型生物反应器(VMFB),该反应器分为好氧区和厌氧区,用于生产生物乙醇。上部好氧区用于糖化,下部厌氧区用于发酵,该技术称为同时糖化和发酵(SSF)。以木薯为原料,研究了联合固定化糖化菌(A. awamori和D. bruxellensis)和发酵菌(Z. mobilis)利用木薯废弃物生产生物乙醇的可行性。好氧反应区采用聚氨酯泡沫塑料,厌氧反应区采用海藻酸钙微球固定化微生物作为载体进行固定化。本研究的主要目的是了解农业废弃物,特别是木薯加工废弃物作为生物乙醇生产原料的可用性,使用SSF技术获得了浓度为8% w/w的乙醇。
{"title":"Design of Experimental Lab Scale Vertical Mass Flow Type Bioreactor for Bioethanol Production by Co-Culture Strategy from Cassava Waste","authors":"R. Prasad, C. Jijina, A. Akhila, T. Johnson, S. Ajayan","doi":"10.3329/jsr.v15i1.59095","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59095","url":null,"abstract":"Due to a surge in demand and cost, there is a requirement for alternative energy sources by devising strategies for the efficient production of biofuels. Immobilized microbial systems for the conversion of biomass to fuels have become progressively important. Cassava (Manihot esculentum) processing waste, a massive byproduct of starch processing is utilized in this work for bioethanol production. This study was an attempt to design and develop an experimental lab-scale Vertical Mass-Flow type Bioreactor (VMFB) demarcated into aerobic and anaerobic zones to produce bioethanol. The upper aerobic zone was meant for saccharification and the lower anaerobic zone for fermentation, the technique is called Simultaneous Saccharification and Fermentation (SSF). The feasibility of co-immobilizing saccharification strains (A. awamori and D. bruxellensis) and fermentation strains (Z. mobilis) for bioethanol production through SSF from cassava agro-waste were tested. Polyurethane foam was used in the aerobic reaction zone and calcium-alginate beads immobilized microorganisms in the anaerobic reaction zone were employed as carriers for the immobilization. The main objective of this study was to understand the usability of agricultural waste, especially cassava processing waste as raw material for bioethanol production, using SSF technology a concentration of 8 % w/w ethanol was obtained.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88731673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability of Cosmological Model in Self-Creation Theory of Gravitation 自我创造引力理论中宇宙模型的稳定性
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59676
A. S. Nimkar, S. Hadole
In the present paper, we considered Bianchi type-II space-time in the presence of a macroscopic body in the self-creation theory formulated by Barber. The relation between metric coefficient and state equation has helped present the exact cosmological model in theory. The features, stability, and some physical & kinematical properties of the obtained model are also discussed.
在本文中,我们考虑了由Barber提出的自我创造理论中存在宏观物体的Bianchi - ii型时空。度规系数与状态方程之间的关系有助于在理论上提出精确的宇宙学模型。讨论了所得到的模型的特征、稳定性以及一些物理和运动特性。
{"title":"Stability of Cosmological Model in Self-Creation Theory of Gravitation","authors":"A. S. Nimkar, S. Hadole","doi":"10.3329/jsr.v15i1.59676","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59676","url":null,"abstract":"In the present paper, we considered Bianchi type-II space-time in the presence of a macroscopic body in the self-creation theory formulated by Barber. The relation between metric coefficient and state equation has helped present the exact cosmological model in theory. The features, stability, and some physical & kinematical properties of the obtained model are also discussed.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91328439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Developments on Brønsted Acid Catalyzed Asymmetric Aldol Reactions and the Fate of the Catalysts Brønsted酸催化不对称醛醇反应的研究进展及催化剂的命运
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59614
J. Das
Since the innovative work of Terada and Akiyama, asymmetric reaction using chiral Brønsted acid has attracted great attention. Asymmetric aldol reactions are extensively studied in different organocatalysis. Brønsted acid-catalyzed aldol reaction may be carried out directly without modification of the substrates or Mukaiyama type aldol reaction using silyl enol ether as nucleophiles. The reaction may proceed through the formation of enol intermediate followed by the attack to the electrophile while Mukaiyama type aldol reactions may follow two mechanistic pathways- Brønsted acidic pathways where Brønsted acid directly activates the substrate or Lewis acid pathways where Brønsted acid acts as pre-catalyst. Here, the recent advancement of asymmetric aldol reactions using chiral Brønsted acid as a catalyst and the fate of the catalysts in the reaction has been discussed in this review. It is observed that some kinds of aldol reactions have rarely been studied and need more attention.
自Terada和Akiyama的创新工作以来,手性Brønsted酸的不对称反应引起了人们的广泛关注。不对称醛醇反应在不同的有机催化中被广泛研究。Brønsted酸催化的醛醇反应可以直接进行,不需要对底物进行修饰,也可以使用硅烯醇醚作为亲核试剂进行Mukaiyama型醛醇反应。该反应可能通过形成烯醇中间体然后攻击亲电试剂进行,而Mukaiyama型醛醇反应可能通过两种机制途径进行:Brønsted酸途径,其中Brønsted酸直接激活底物;或Lewis酸途径,其中Brønsted酸作为预催化剂。本文综述了近年来以手性Brønsted酸为催化剂的不对称醛醇反应的研究进展及催化剂在该反应中的作用。观察到一些类型的醛醇反应很少被研究,需要更多的关注。
{"title":"Recent Developments on Brønsted Acid Catalyzed Asymmetric Aldol Reactions and the Fate of the Catalysts","authors":"J. Das","doi":"10.3329/jsr.v15i1.59614","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59614","url":null,"abstract":"Since the innovative work of Terada and Akiyama, asymmetric reaction using chiral Brønsted acid has attracted great attention. Asymmetric aldol reactions are extensively studied in different organocatalysis. Brønsted acid-catalyzed aldol reaction may be carried out directly without modification of the substrates or Mukaiyama type aldol reaction using silyl enol ether as nucleophiles. The reaction may proceed through the formation of enol intermediate followed by the attack to the electrophile while Mukaiyama type aldol reactions may follow two mechanistic pathways- Brønsted acidic pathways where Brønsted acid directly activates the substrate or Lewis acid pathways where Brønsted acid acts as pre-catalyst. Here, the recent advancement of asymmetric aldol reactions using chiral Brønsted acid as a catalyst and the fate of the catalysts in the reaction has been discussed in this review. It is observed that some kinds of aldol reactions have rarely been studied and need more attention.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87162866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro Micropropagation of Bergenia ligulata (Hook. f. & Thomson) Engl. through Leaf Explant 柳根草(Bergenia ligulata)的离体微繁。f. &汤姆森)英国透叶外植体
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59313
S. Padma Rani, R. Puri, A. Qasim, P. Boora, D. Angmo
Berginia ligulata is medicinally significant and endangered plant of the western Himalayan Region. This plant is used to treat many diseases such as urinary problems and heart problems. By using leaf explant, an efficient and rapid micropropagation protocol was developed. In in-vitro propagation, MS medium was supplemented with benzyl amino purine (BAP), 1-naphthalene acetic acid (NAA) and indol-3-acetic acid (IAA) to induce multiple shoots from leaf explants. The most positive response for the formation of calluses was observed on MS media supplemented with MS medium + BAP(1 mg/L) + NAA(1 mg/L) followed by MS medium + BAP (0.5 mg/L) + NAA (1 mg/L) after 3 weeks. Maximum number of shoots were obtained on MS medium + BAP (2 mg/L) +IAA (2 mg/L). Maximum % shoot response was obtained on MS medium + Kn (2.5 mg/L) concentration. The maximum number of roots was observed on MS medium without growth regulators. These well-rooted plants were established in pots and acclimatized in the lab and transferred to field conditions. This process is useful to produce endangered plants on large scale.
柳杉是喜马拉雅西部地区一种具有重要药用价值的濒危植物。这种植物被用来治疗许多疾病,如泌尿系统问题和心脏问题。利用叶片外植体,开发了一种高效、快速的微繁方案。在离体繁殖中,在MS培养基中添加苯氨基嘌呤(BAP)、1-萘乙酸(NAA)和吲哚-3-乙酸(IAA),诱导叶片外植体多芽。MS培养基中添加MS + BAP(1mg /L) + NAA(1mg /L)对愈伤组织的形成最有利,3周后再添加MS + BAP(0.5 mg/L) + NAA(1mg /L)。MS + BAP (2 mg/L) +IAA (2 mg/L)处理的芽数最多。在MS培养基+ Kn (2.5 mg/L)浓度下,茎部响应最大。在不添加生长调节剂的MS培养基上,根数最多。这些根系良好的植物在盆栽中培养,在实验室中驯化,然后转移到田间条件下。该工艺可用于濒危植物的大规模生产。
{"title":"In vitro Micropropagation of Bergenia ligulata (Hook. f. & Thomson) Engl. through Leaf Explant","authors":"S. Padma Rani, R. Puri, A. Qasim, P. Boora, D. Angmo","doi":"10.3329/jsr.v15i1.59313","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59313","url":null,"abstract":"Berginia ligulata is medicinally significant and endangered plant of the western Himalayan Region. This plant is used to treat many diseases such as urinary problems and heart problems. By using leaf explant, an efficient and rapid micropropagation protocol was developed. In in-vitro propagation, MS medium was supplemented with benzyl amino purine (BAP), 1-naphthalene acetic acid (NAA) and indol-3-acetic acid (IAA) to induce multiple shoots from leaf explants. The most positive response for the formation of calluses was observed on MS media supplemented with MS medium + BAP(1 mg/L) + NAA(1 mg/L) followed by MS medium + BAP (0.5 mg/L) + NAA (1 mg/L) after 3 weeks. Maximum number of shoots were obtained on MS medium + BAP (2 mg/L) +IAA (2 mg/L). Maximum % shoot response was obtained on MS medium + Kn (2.5 mg/L) concentration. The maximum number of roots was observed on MS medium without growth regulators. These well-rooted plants were established in pots and acclimatized in the lab and transferred to field conditions. This process is useful to produce endangered plants on large scale.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89523173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engineering of Aberrated PSF by Asymmetric Apodization with the Complex Shaded Aperture 复合遮光孔径不对称离形的像差PSF工程
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.60366
M. Venkanna, N. Sabitha, D. K. Sagar
The point spread function (PSF) produced by a coherent optical system under the influence of defocus, coma, and primary spherical aberration (PSA) is examined in this work. This paper deals with asymmetric apodization and pupil engineering to control monochromatic aberrations. To reduce the influence of monochromatic aberrations on the diffracted PSF, this approach uses amplitude and phase apodization. Analytical investigations on intensity PSF are carried out with varying amounts of aberrations and degrees of amplitude and phase apodization. Computed central peak intensity and full width at half maxima (FWHM) and analyzed. The resolution of a diffraction-limited optical imaging system is improved by using an asymmetric optical filter that minimizes the effect of defocus.
本文研究了相干光学系统在离焦、彗差和初级球差影响下产生的点扩展函数(PSF)。本文讨论了控制单色像差的非对称消瞳和瞳工程。为了减少单色像差对衍射PSF的影响,该方法采用幅度和相位消去。分析研究了不同程度的像差和振幅和相位apoification的强度PSF。计算中心峰强度和半峰全宽(FWHM)并进行分析。通过使用非对称滤光片来减小离焦的影响,提高了衍射受限光学成像系统的分辨率。
{"title":"Engineering of Aberrated PSF by Asymmetric Apodization with the Complex Shaded Aperture","authors":"M. Venkanna, N. Sabitha, D. K. Sagar","doi":"10.3329/jsr.v15i1.60366","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.60366","url":null,"abstract":"The point spread function (PSF) produced by a coherent optical system under the influence of defocus, coma, and primary spherical aberration (PSA) is examined in this work. This paper deals with asymmetric apodization and pupil engineering to control monochromatic aberrations. To reduce the influence of monochromatic aberrations on the diffracted PSF, this approach uses amplitude and phase apodization. Analytical investigations on intensity PSF are carried out with varying amounts of aberrations and degrees of amplitude and phase apodization. Computed central peak intensity and full width at half maxima (FWHM) and analyzed. The resolution of a diffraction-limited optical imaging system is improved by using an asymmetric optical filter that minimizes the effect of defocus.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89070198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microwave Assisted Synthesis, Characterisation and Biological Activities of Cu(II) Complexes of Few Thiosemicarbazones Ligands 几种硫代氨基脲配体Cu(II)配合物的微波合成、表征及生物活性研究
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.60772
K. Verma, N. Nirwan, R. Singh, N. Bhojak
Thiosemicarbazones are class of compounds which are obtained by the condensation of thiosemicarbazide with carbonyl compounds. The transition metal complexes of thiosemicarbazones are widely considered due to their broad spectrum of biological activities such as antibacterial, antitumor and antifungal activities. In present research work a series of four novel Cu(II) aryl thiosemicarbazones complexes having the general composition [Cu(L1)2Cl2], [Cu(L2)2Cl2], [Cu(L3)2Cl2] and [Cu(L4)2Cl2]{where L1= 4-nitroacetophenone thiosemicarbazones (4NAT), L2 = 3-nitrobenzaldehyde thiosemicarbazone (3NBT), L3 = 4-hydroxybenzaldehyde thiosemicarbazone (4HBT) and L4 = 4-aminoacetophenone thiosemicarbazone (4AAT)} have been synthesized by the reaction of thiosemicarbazide with substituted aromatic aldehydes and ketones by conventional heating as well as microwave irradiations method followed by complexation with Cu(II) metal. The synthesized compounds have been characterised by elemental analysis, melting point determination, FTIR, UV-visible spectral analysis. Thiosemicarbazone ligands behave as bidentate ligand and forms octahedral complexes with Cu(II). The synthesized ligands and their new metal complexes have been screened in vitro for antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis bacteria. The result shows that all the Cu(II) complexes are potent antibacterial agents against these bacteria.
硫代氨基脲是由硫代氨基脲与羰基化合物缩合而成的一类化合物。硫代氨基脲类过渡金属配合物因其广泛的抗菌、抗肿瘤、抗真菌等生物活性而受到广泛的关注。本文研究了四种新型的Cu(II)芳基硫代氨基脲配合物,其一般组成为[Cu(L1)2Cl2], [Cu(L2)2Cl2], [Cu(L3)2Cl2]和[Cu(L4)2Cl2]{其中L1= 4-硝基苯乙酮硫代氨基脲(4NAT), L2 = 3-硝基苯甲醛硫代氨基脲(3NBT),以硫代氨基脲为原料,采用常规加热法和微波辐照法,与金属铜络合,合成了L3 = 4-羟基苯甲醛硫代氨基脲(4HBT)和L4 = 4-氨基苯乙酮硫代氨基氨基脲(4AAT)。对合成的化合物进行了元素分析、熔点测定、红外光谱、紫外可见光谱等表征。硫代氨基脲配体表现为双齿配体,与Cu(II)形成八面体配合物。合成的配体及其新的金属配合物对大肠杆菌、金黄色葡萄球菌和枯草芽孢杆菌的体外抗菌活性进行了筛选。结果表明,所有Cu(II)配合物都是有效的抑菌剂。
{"title":"Microwave Assisted Synthesis, Characterisation and Biological Activities of Cu(II) Complexes of Few Thiosemicarbazones Ligands","authors":"K. Verma, N. Nirwan, R. Singh, N. Bhojak","doi":"10.3329/jsr.v15i1.60772","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.60772","url":null,"abstract":"Thiosemicarbazones are class of compounds which are obtained by the condensation of thiosemicarbazide with carbonyl compounds. The transition metal complexes of thiosemicarbazones are widely considered due to their broad spectrum of biological activities such as antibacterial, antitumor and antifungal activities. In present research work a series of four novel Cu(II) aryl thiosemicarbazones complexes having the general composition [Cu(L1)2Cl2], [Cu(L2)2Cl2], [Cu(L3)2Cl2] and [Cu(L4)2Cl2]{where L1= 4-nitroacetophenone thiosemicarbazones (4NAT), L2 = 3-nitrobenzaldehyde thiosemicarbazone (3NBT), L3 = 4-hydroxybenzaldehyde thiosemicarbazone (4HBT) and L4 = 4-aminoacetophenone thiosemicarbazone (4AAT)} have been synthesized by the reaction of thiosemicarbazide with substituted aromatic aldehydes and ketones by conventional heating as well as microwave irradiations method followed by complexation with Cu(II) metal. The synthesized compounds have been characterised by elemental analysis, melting point determination, FTIR, UV-visible spectral analysis. Thiosemicarbazone ligands behave as bidentate ligand and forms octahedral complexes with Cu(II). The synthesized ligands and their new metal complexes have been screened in vitro for antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis bacteria. The result shows that all the Cu(II) complexes are potent antibacterial agents against these bacteria.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72480379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Haematological, Serum Biochemical and Histopathological Changes in Acute and Sub-Chronic Aqueous Extract of Oyster Mushroom in Male Wistar Rats 平菇水提液急性和亚慢性对雄性Wistar大鼠血液学、血清生化和组织病理学的影响
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59309
T. Garuba, I. T. Olabanji, O. M. Awogboro, G. Olahan, S. Atunwa, O. A. Ahmed, A. Aremu, M. Bolaji, A. A. Adegboye, S. Sabiu
This study aimed at evaluating toxicological implications of aqueous P. ostreatus extract (POE) in male Wistar rats. POE was prepared in 1:10 (pulverized P. ostreatus : distilled water). In  acute toxicity test, single oral dose of 2 mL/kg of POE was administered and observed for 28 days. The sub-chronic toxicity study was conducted by daily oral administration of graded doses (0.25, 0.50 and 0.75 mL/kg b.w) of the extract for 28 days. Clinical signs of toxicity, hematological, serum biochemical parameters and histopathological studies were subsequently evaluated. No treatment-related signs of toxicity or mortality in the animals were recorded in both toxicity tests. Rats administered with lowest dose of POE (25 mL/kg) had highest percentage weight gain. POE had no significant difference (P>0.05) on Red Blood Cell, White Blood Cell (WBC) and differential WBC, and serum biochemistry across all the treated groups when compared to the controls. The result of photomicrographs of stomach, spleen, heart, lung, kidney and liver showed a well outlined arrays of normal tissues in both acute and sub-chronic doses connoting that POE had no toxic effect on them. In view of these, POE may be concluded to be non-toxic within the tested doses and period of investigation.
本研究旨在评价水提物(POE)对雄性Wistar大鼠的毒理学影响。POE以1:10的比例(山参粉:蒸馏水)制备。急性毒性试验,单次口服2 mL/kg POE,观察28 d。亚慢性毒性研究采用分级剂量(0.25、0.50和0.75 mL/kg b.w)每日口服,持续28天。随后评估临床毒性症状、血液学、血清生化参数和组织病理学研究。在两次毒性试验中均未记录到与治疗相关的毒性或死亡迹象。给予最低剂量POE (25 mL/kg)的大鼠体重增加百分比最高。与对照组相比,各治疗组的红细胞、白细胞(WBC)、差异白细胞(WBC)及血清生化指标均无显著差异(P>0.05)。胃、脾、心、肺、肾和肝的显微照片显示,急性和亚慢性剂量下的正常组织排列良好,这意味着POE对它们没有毒性作用。鉴于这些,POE可以在测试剂量和调查期间内得出无毒的结论。
{"title":"Haematological, Serum Biochemical and Histopathological Changes in Acute and Sub-Chronic Aqueous Extract of Oyster Mushroom in Male Wistar Rats","authors":"T. Garuba, I. T. Olabanji, O. M. Awogboro, G. Olahan, S. Atunwa, O. A. Ahmed, A. Aremu, M. Bolaji, A. A. Adegboye, S. Sabiu","doi":"10.3329/jsr.v15i1.59309","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59309","url":null,"abstract":"This study aimed at evaluating toxicological implications of aqueous P. ostreatus extract (POE) in male Wistar rats. POE was prepared in 1:10 (pulverized P. ostreatus : distilled water). In  acute toxicity test, single oral dose of 2 mL/kg of POE was administered and observed for 28 days. The sub-chronic toxicity study was conducted by daily oral administration of graded doses (0.25, 0.50 and 0.75 mL/kg b.w) of the extract for 28 days. Clinical signs of toxicity, hematological, serum biochemical parameters and histopathological studies were subsequently evaluated. No treatment-related signs of toxicity or mortality in the animals were recorded in both toxicity tests. Rats administered with lowest dose of POE (25 mL/kg) had highest percentage weight gain. POE had no significant difference (P>0.05) on Red Blood Cell, White Blood Cell (WBC) and differential WBC, and serum biochemistry across all the treated groups when compared to the controls. The result of photomicrographs of stomach, spleen, heart, lung, kidney and liver showed a well outlined arrays of normal tissues in both acute and sub-chronic doses connoting that POE had no toxic effect on them. In view of these, POE may be concluded to be non-toxic within the tested doses and period of investigation.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82342280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A SOA and DBUS-based Robotic Component Interaction 基于SOA和dbus的机器人组件交互
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.57545
R. P. Srivastava, L. S. Umrao, R. Yadav
Rewriting and executing codes violate the SOLID principle of object-oriented programming. Robotics being an emerging platform, it becomes hard to write the code from scratch. We focus on using what is already built in as a Robotics Component instead of writing something from scratch. The intention is to minimize development effort and produce the desired result on time without rewriting the software components. By allowing functionalities of different components to be brought into a single component, we are saving the time required for code conversion or replication of functionality written in one language to another. So an architecture with these properties seems ideal for integrating different components. Integration is one of the most fundamental problems in designing autonomous mobile robots, especially those interacting with people in real-life settings. This paper presents an approach to building complex systems from different robotics packages available as open source components (PLAYER, STAGE, GAZEBO, CARMEN). DBUS is a message-oriented protocol for communicating among processes running on the same desktop. SOA provides access to the services over the network and adds novelty to our application.
重写和执行代码违反了面向对象编程的SOLID原则。机器人技术是一个新兴的平台,从头开始编写代码变得很困难。我们专注于使用已经内置的机器人组件,而不是从头开始编写。这样做的目的是尽量减少开发工作量,并在不重写软件组件的情况下按时产生所需的结果。通过允许将不同组件的功能整合到一个组件中,我们节省了代码转换或将用一种语言编写的功能复制到另一种语言所需的时间。因此,具有这些属性的体系结构似乎非常适合集成不同的组件。集成是设计自主移动机器人的最基本问题之一,尤其是那些在现实生活中与人互动的机器人。本文提出了一种从不同的机器人软件包构建复杂系统的方法,这些软件包可用作开源组件(PLAYER, STAGE, GAZEBO, CARMEN)。DBUS是一种面向消息的协议,用于在同一桌面上运行的进程之间进行通信。SOA通过网络提供对服务的访问,并为我们的应用程序增加了新颖性。
{"title":"A SOA and DBUS-based Robotic Component Interaction","authors":"R. P. Srivastava, L. S. Umrao, R. Yadav","doi":"10.3329/jsr.v15i1.57545","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.57545","url":null,"abstract":"Rewriting and executing codes violate the SOLID principle of object-oriented programming. Robotics being an emerging platform, it becomes hard to write the code from scratch. We focus on using what is already built in as a Robotics Component instead of writing something from scratch. The intention is to minimize development effort and produce the desired result on time without rewriting the software components. By allowing functionalities of different components to be brought into a single component, we are saving the time required for code conversion or replication of functionality written in one language to another. So an architecture with these properties seems ideal for integrating different components. Integration is one of the most fundamental problems in designing autonomous mobile robots, especially those interacting with people in real-life settings. This paper presents an approach to building complex systems from different robotics packages available as open source components (PLAYER, STAGE, GAZEBO, CARMEN). DBUS is a message-oriented protocol for communicating among processes running on the same desktop. SOA provides access to the services over the network and adds novelty to our application.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82703885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Affirmative Fixed Point Result on b-Metric Spaces using (CLR) Property 利用(CLR)性质在b-度量空间上的一个肯定不动点结果
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.59988
V. Rao, U. Dixit
This study aims to show that four maps in a b-metric space that satisfy pairwise weak compatibility have common fixed points under certain conditions. In the main results of this paper, (CLR) property is employed, and common fixed points for four weakly compatible mappings are established. All our findings are backed up by befitting examples. Our results generalize and extend certain previous findings in the literature.
本研究旨在证明b-度量空间中满足成对弱相容的四个映射在一定条件下具有公共不动点。在本文的主要结果中,利用(CLR)性质,建立了4个弱相容映射的公共不动点。我们所有的发现都有合适的例子支持。我们的结果概括和扩展了文献中某些先前的发现。
{"title":"An Affirmative Fixed Point Result on b-Metric Spaces using (CLR) Property","authors":"V. Rao, U. Dixit","doi":"10.3329/jsr.v15i1.59988","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.59988","url":null,"abstract":"This study aims to show that four maps in a b-metric space that satisfy pairwise weak compatibility have common fixed points under certain conditions. In the main results of this paper, (CLR) property is employed, and common fixed points for four weakly compatible mappings are established. All our findings are backed up by befitting examples. Our results generalize and extend certain previous findings in the literature.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90105304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shannon Information Entropy Sum of a Free Particle in Three Dimensions Using Cubical and Spherical Symmetry 三维自由粒子的三次和球面对称Shannon信息熵和
Pub Date : 2023-01-01 DOI: 10.3329/jsr.v15i1.60067
S. Singh, A. Saha
In this paper, the plane wave solutions of a free particle in three dimensions for Cubical and Spherical Symmetry have been considered. The coordinate space wave functions for the Cubical and Spherical Symmetry are obtained by solving the Schrdinger differential equation. The momentum space wave function is obtained by using the operator form of an observable in the case of Cubical Symmetry. For Spherical Symmetry, the same is obtained by taking the Fourier transform of the respective coordinate space wave function. The wave functions have been used to constitute probability densities in coordinate and momentum space for both the symmetries. Further, the Shannon information entropy has been computed both in coordinate and momentum space respectively for  (L is the length of the side of the cubical box) values for Cubical Symmetry and for  values in Spherical Symmetry keeping (k is the wave vector and p is the momentum of the free particle) constant. The values obtained for the Shannon information entropies are found to satisfy the Bialynicki-Birula and Myceilski (BBM) inequality at larger  values () in case of Cubical Symmetry and for values of  and  in Spherical Symmetry.
本文研究了三次对称和球对称的三维自由粒子的平面波解。通过求解薛定谔微分方程,得到了三次对称和球次对称的空间坐标波函数。在立方对称的情况下,利用可观测值的算子形式得到了动量空间波函数。对于球对称,通过对各自的坐标空间波函数进行傅里叶变换可以得到相同的结果。用波函数在坐标空间和动量空间中构成两种对称的概率密度。此外,在坐标空间和动量空间中分别计算了立方体对称(L为立方箱边的长度)值和球对称(k为波矢量,p为自由粒子的动量)保持常数的香农信息熵。得到的Shannon信息熵值在立方体对称和球对称的情况下满足Bialynicki-Birula和Myceilski (BBM)不等式。
{"title":"Shannon Information Entropy Sum of a Free Particle in Three Dimensions Using Cubical and Spherical Symmetry","authors":"S. Singh, A. Saha","doi":"10.3329/jsr.v15i1.60067","DOIUrl":"https://doi.org/10.3329/jsr.v15i1.60067","url":null,"abstract":"In this paper, the plane wave solutions of a free particle in three dimensions for Cubical and Spherical Symmetry have been considered. The coordinate space wave functions for the Cubical and Spherical Symmetry are obtained by solving the Schrdinger differential equation. The momentum space wave function is obtained by using the operator form of an observable in the case of Cubical Symmetry. For Spherical Symmetry, the same is obtained by taking the Fourier transform of the respective coordinate space wave function. The wave functions have been used to constitute probability densities in coordinate and momentum space for both the symmetries. Further, the Shannon information entropy has been computed both in coordinate and momentum space respectively for  (L is the length of the side of the cubical box) values for Cubical Symmetry and for  values in Spherical Symmetry keeping (k is the wave vector and p is the momentum of the free particle) constant. The values obtained for the Shannon information entropies are found to satisfy the Bialynicki-Birula and Myceilski (BBM) inequality at larger  values () in case of Cubical Symmetry and for values of  and  in Spherical Symmetry.","PeriodicalId":16984,"journal":{"name":"JOURNAL OF SCIENTIFIC RESEARCH","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72976596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
JOURNAL OF SCIENTIFIC RESEARCH
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1