Objectives: In people with multiple sclerosis (PWMS), exercise improves aerobic capacity and muscle strength which are key components of physical function and overall health status. However, the effects diminish after exercise cessation. Therefore, the present study aimed to investigate whether exercise booster sessions (EBS) could preserve the exercise-induced improvements.
Design: Multicentre RCT.
Methods: Ninety-four PWMS performed 12 weeks of aerobic-training (AT) or resistance-training (RT) and were subsequently randomised to receive EBS (two sessions every fifth week) (ATboost n = 24, RTboost n = 24) or usual-care (ATuc n = 20, or RTuc n = 26) for 40 weeks. The primary outcome was physical function measured as a composite score of the six-minute walk test (6MWT) and five-time sit-to-stand test (5STS). Secondary outcomes were aerobic capacity and muscle strength.
Results: No between-group difference was observed in the composite score of 6MWT and 5STS (arbitrary unit) between ATboost and RTboost 0.00 [-0.20; 0.20]. No between-group difference was observed for aerobic capacity (mL O2/kg/min) between ATboost and ATuc 1.1 [-1.9; 4.1], although a within-group change was observed for ATboost -1.9 [-4.0; 0.1], but not for ATuc -3.0 [-5.2; -0.8]. No between-group difference was seen for muscle strength (Nm/kg) between RTboost and RTuc -0.04 [-0.36; 0.28]. Also, no within-group change was observed for neither RTboost -0.07 [-0.30; 0.14] nor RTuc -0.04 [-0.27; 0.20].
Conclusions: EBS had no apparent effect on preservation of physical function, aerobic capacity, or muscle strength in PWMS. Muscle strength was preserved regardless of group, whereas only ATboost preserved exercise-induced improvements in aerobic capacity.
Objectives: To examine the effect of routine physical exercises (PhExs) targeted to the abdomen, compared to general exercises, on clinical outcomes, biomarkers, and quality of life (QoL) in patients with inflammatory bowel diseases.
Methods: This randomized, controlled (1:1), double-blind, pilot study assessed the effect of following 15-minute videos of either a specific abdominally targeted PhEx inspired by yoga or non-targeted general exercise, at least 6 times a week, on the disease activity in patients with IBD. Disease activity, inflammatory indices (CRP and fecal calprotectin), and QoL measures (PROMIS-29) were compared before and after 4 weeks of intervention.
Results: Twenty-six patients with mild-to-moderate IBD activity (15 Crohn's disease [CD], 11 ulcerative colitis [UC]) were included in the analysis. At the end of the intervention, most patients with IBD in both arms exhibited significant improvements in their clinical scores. However, clinical remission rates were significantly higher among patients with CD (intervention-75 % vs. control-14 %; p < 0.05), but not with UC. Fecal calprotectin remained stable in the interventional group, while it increased in the control group (change in calprotectin: -1 μg/g vs. +104 μg/g, respectively, p < 0.05). Some of the QoL measures improved compared to baseline but this was not specific to the abdominally targeted exercises.
Conclusions: Performance of daily abdominally targeted physical exercises demonstrated clinical improvement and biomarker stabilization, particularly among patients with CD, despite small sample size and short duration, underscoring the potential benefits of physical exercises and specifically those that activate the abdomen.
Objectives: This study explores how medical staff in German elite handball interpret their roles in managing athlete health and how they navigate role-related challenges within the performance-driven context of elite sport.
Design: Qualitative study using a constructivist framework, positing that reality is constructed through active engagement with and interpretation of experiences.
Methods: Twenty semi-structured interviews were conducted with doctors and physiotherapists (n = 10 each) working in Germany's elite handball system, including the national team and Bundesliga clubs. A reflexive thematic analysis of the data was conducted, focusing on patterns of meaning to gain a nuanced understanding of the complex role interpretations of medical staff.
Results: We generated five roles for medical staff in elite handball: (1) Decide, (2) Coordinate, (3) Educate, (4) Enable, and (5) Protect. These roles illustrate the interdependence between the visible, compensated work and invisible, often unrecognized work that medical staff perform. Within each role we uncovered tensions between athlete care and performance imperatives. Ethical dilemmas arose in relation to analgesic use and return to sport. Participants described role ambiguity due to unclear boundaries and expectations.
Conclusions: Doctors and physiotherapists in elite handball navigate complex and ethically charged roles. Their unseen labor and boundary work are central to athlete health management but remain under-supported in current sport systems. Recommendations include interdisciplinary communication training, clearer ethical codes, and employing independent medical staffing. Future research should examine cooperative decision-making from multiple perspectives and over time.
Objectives: This study describes core temperature (Tcore) responses during football matches in warm to hot conditions. It aims to identify which physiological, running, and perceptual factors are associated with reaching high Tcore values while controlling for environmental conditions and cooling.
Design: Forty highly trained male youth football players participated in at least two out of four matches held at temperatures between 26 and 42 °C. In three matches, heat mitigation strategies (passive rest and 17 °C drinks, or cold towels and 5 °C drinks) were applied pre-match, at half-time, and in additional breaks per half.
Methods: Match running, heart rates, hydration markers, and perceptual responses were measured and checked for associations with peak Tcore values via linear mixed models accounting for environmental conditions and heat mitigation strategies.
Results: Peak Tcore was 39.2 ± 0.5 °C (range: 37.9-40.1 °C). Higher total distance (β = 0.39 [0.13, 0.64], p = 0.004) and distance at low-to-moderate speeds (β = 0.44 [0.18, 0.69], p = 0.001) were associated with higher peak Tcore, while walking distance was inversely associated (β = -0.42 [-0.69, -0.15], p = 0.003). High-speed and sprinting distances were not associated with peak Tcore. Higher heart rate (β = 0.37 [0.10, 0.64], p = 0.008), sweat loss (β = 0.38 [0.14, 0.62], p = 0.002) and body mass loss (β = 0.20 [0.00, 0.40], p = 0.047) were also associated with higher peak Tcore. Rating-of-fatigue (p = 0.74), perceived exertion (p = 0.78), and thermal sensation (p = 0.98) were not associated with peak Tcore.
Conclusions: High Tcore peaks were observed in all conditions and were associated with higher heart rate, sweat loss, and match running. Covering more distance at low-to-moderate speed was associated with a higher heat strain, whereas walking more (instead of running) was associated with lower Tcore peaks.
Objectives: Swimming-induced pulmonary oedema (SIPE) is a potentially fatal condition associated with open-water swims. We sought to quantify the contribution of cardiac dysfunction to SIPE.
Design: We aimed to assess the incidence of SIPE during an endurance cold water swim. We determined associations between SIPE and changes in cardiac function through a SIPE questionnaire, lung ultrasound (LUS), cardiac biomarkers (N-Terminal pro-B-type natriuretic peptide (NT proBNP) and cardiac troponin I (cTnI)) and transthoracic echocardiograms (TTE).
Methods: Twenty open-water swimmers (10 males) underwent a TTE, LUS for pulmonary oedema and cardiac biomarkers before, 2-hours and 24-hours after an 8-hour swim. Swimmers had an additional LUS and rated their breathlessness upon leaving the water. Participants with breathlessness and 3 or more B-lines present in two or more LUS views were considered SIPE positive.
Results: Five swimmers (25 % of cohort) presenting with post-event breathlessness and evidence of lung water were considered SIPE positive. SIPE had no demonstrable effect on left systolic function (LV ejection fraction, global longitudinal strain [GLS]), diastolic function (left atrial volume, E/e') and right ventricular (RV) function (RV fractional area change and RV free wall GLS). SIPE was associated with a small increase in troponin post-swim (at 2 hours SIPE+ 32.1 ng/L, SIPE- 12.6 ng/L, p = 0.004: at 24 hours SIPE+ 12.6 ng/L, SIPE- 4.8 ng/L, p = 0.04) but had no impact on NT proBNP.
Conclusions: SIPE is common in open-water swimmers following an endurance swim and is identified using LUS. Whilst SIPE was associated with a small increase in post-swim troponin levels, no further evidence of cardiac dysfunction was identified at two hours after the swim to explain the pulmonary oedema.
Objectives: To identify facilitators and barriers to implementing an injury surveillance system for amateur boxing in Australia, and to evaluate an implementation trial of an injury surveillance system.
Design: Mixed methods research.
Methods: (1) Semi-structured interviews of key informants from the Australian amateur boxing community (i.e. athletes, coaches, promoters, referees, medical professionals, and boxing governing body officials) were transcribed and subjected to a reflexive thematic analysis. (2) Implementation trial of an injury surveillance system at five amateur boxing events in Australia was evaluated using the reach, effectiveness, adoption, implementation, and maintenance framework indicators; however, the maintenance domain was not evaluated.
Results: Three primary themes were generated in the reflexive thematic analysis: (1) value of data, which included sub-themes on growing the sport, improving athlete performance, and informing educational activities; (2) trust, which was engendered by a strong sense of rapport and connection between the boxing community and the research team; and (3) barriers to implementation, which included sub-themes on fear, resistance to change, and process requirements. The implementation trial involved five amateur boxing events, which comprised a total of 210 registered athletes, of which 181 were eligible to participate in this research. The reach indicator was 81 %, the four effectiveness indicators ranged from 86 % to 100 %, the adoption indicator was 100 %, and implementation indicator was 100 %.
Conclusions: It is feasible to implement an injury surveillance system and obtain good-quality data in the amateur boxing setting in Australia, but there are potential barriers to implementation at scale.
Objectives: Trail runners often experience illness during event preparation. We aimed to prospectively determine prevalence, incidence, clinical characteristics, severity (time-loss, burden) and associated illness risk factors amongst South African male and female recreational trail runners of different ages over a 30-week training period.
Design: Prospective cohort.
Methods: Illness and training data from 152 trail runners (120 males, 32 females) were collected every 14 days over 30 weeks using the updated OSTRC-H questionnaire. Illness prevalence (%), incidence (I: per 1000 trail running exposure-days), incidence ratio (IR), severity [% time-loss; illness burden (IB: days lost/1000 trail running exposure-days)], and associated risk factors are reported.
Results: Over 30 weeks, 52 % of runners reported illness, with a mean two-week all-illness prevalence of 10.1 %. The overall illness incidence was 7.2 (95 % CI: 5.7-9.2). The winter-to-summer IR was 1.6 (p = 0.022). Illness incidence in females (I = 9.7) was higher than in males (I = 6.6), with a female:male IR of 1.5 (p < 0.05). Most illnesses affected the respiratory (64.3 %), digestive (15.9 %) and musculoskeletal (5.7 %) systems. Moderate illness severity (8-28 days time-loss) occurred in 29.3 % of runners. The overall IB was 43.2 days lost. BMI ≥25 kg/m2 was associated with illness, but no significant illness risk factors were identified via Poisson regression.
Conclusions: During a 30-week training period, 52 % of runners reported illness, with a higher incidence in females. The respiratory tract accounted for >60 % of illnesses. One in three trail runners experienced >one week time-loss. A higher BMI >25 kg/m2 was associated with illness. Further research is needed to identify risk factors and develop prevention strategies.
Objectives: To investigate Australian Football players' perceptions of the safety and performance attributes of artificial turf, considering the influences of gender, surface composition, level of exposure and injury status.
Design: Cross-sectional.
Methods: Senior male and female Australian Football players, 18-35 years, from two clubs training and competing on artificial turf were invited to participate. Players completed a validated and reliable questionnaire assessing their perceptions of physical performance and injury risk on artificial turf.
Results: 118 community-level Australian Football players completed the questionnaire: 68 males and 50 females. Overall, players preferred artificial turf in wet conditions (57.3 %) and natural turf in dry conditions (71.4 %). Natural turf was also favoured for competition (82.2 %) and training (55.0 %). Females and individuals with greater exposure - defined by the frequency of turf interactions - preferred artificial turf for training, and wet conditions (p < 0.05). Gender (p = 0.031) and injury status (p = 0.008) significantly impacted performance-related perceptions. Players' preferences and their perceptions of performance and injury risk were significantly influenced by the surface composition (p < 0.001). Skin-related injuries (48.3 %) were the most commonly self-reported injury. Significant differences in injury likelihood and/or severity statements were found when analysed by gender (p = 0.011), exposure (p < 0.001), injury status (p < 0.05) and surface composition (p < 0.05).
Conclusions: These findings demonstrate that player perceptions of artificial turf are influenced not only by surface composition but also by individual experiences and biases. By recognising and responding to these individual factors, stakeholders in the Australian Football community can refine their approaches to encourage acceptance and adoption of artificial turf.
Objectives: To examine associations between 24-hour movement composition in primary school-aged children and later BMI, quality of life, and behavioural outcomes, and to assess the impact of reallocating time between behaviours.
Design: Longitudinal study.
Methods: Data from waves 3, 6, and 7 of the Longitudinal Study of Australian Children (n = 2064; 47 % girls; aged 5 to 12) were analysed. Movement behaviours (screen time, sleep, and physical activity) assessed at ages 5 and 10 were treated as exposures, and follow-up outcomes at ages 10 and 12 included BMI, health-related quality of life (PedsQL), and behavioural difficulties (SDQ). Compositional data analysis examined the longitudinal associations between movement behaviour composition and these outcomes, whilst isotemporal substitution analysis estimated the effects of reallocating 30 min between behaviours.
Results: Compositional analysis showed that higher screen time at age 5 was associated with higher BMI, lower quality of life, and more behavioural difficulties at ages 10 and 12. In contrast, more physical activity and longer sleep at age 5 were associated with lower BMI, higher quality of life, and fewer behavioural problems later in childhood. Isotemporal substitution analysis revealed that replacing 30 min of screen time with physical activity or sleep improved outcomes: lowering BMI, enhancing quality of life, and reducing behavioural difficulties at follow-up.
Conclusions: Shifts in daily movement behaviour composition are associated with key health outcomes in children. These findings support the need for integrated public health strategies that reduce screen time, encourage physical activity, and promote healthy sleep to improve well-being.

