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COLD INDUCES EXPRESSION OF GENES SPECIFIC TO THERMOGENESIS (PGC-1α, UCP1) AND BEIGE CELLS (TMEM26, SLC27A1) IN MOUSE INGUINAL WHITE ADIPOSE TISSUE 低温诱导小鼠腹股沟白色脂肪组织中产热特异性基因(pgc-1α, ucp1)和米色细胞(tmem26, slc27a1)的表达
Pub Date : 2022-06-01 DOI: 10.18173/2354-1059.2022-0029
Hoan Le Ngoc
Studying adaptive thermogenic responses as being a strategy to protect against several metabolic disorders. The browning process is a crucial point of adaptive thermogenic responses. The present study was carried out to examine whether inguinal white adipose tissue (iWAT) is a candidate for the browning process. Mice were caged in a 4 °C cold chamber (Cold group) for 24 hours and 23 °C room temperature condition (RT group). The result showed that mRNA expression of genes specific to thermogenesis, including peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) and uncoupling protein 1 (UCP1), was markedly upregulated in iWAT of the mice in the Cold group compared to the mice in the RT group. Consistent with this, mRNA expression of the Transmembrane protein 26 (TMEM26) gene, specific to beige cells, was also significantly higher in the iWAT of the cold exposed mice than that in the iWAT of the mice housed at room temperature. Expression of solute carrier family 27member 1 (SLC27A1) gene, another gene coding for a protein of beige cells, was tendency to increase in iWAT of the cold exposed mice compared with that in iWAT of the control mice. However, this change was not significantly differed between the two groups. These data demonstrate that iWAT is an important tissue responding to cold-induced thermogenesis and browning process. Thus, iWAT is a promising candidate for further studies on the mechanism of cold-induced thermogenic responses in white adipose tissues.
研究适应性产热反应作为保护几种代谢紊乱的策略。褐变过程是适应性产热反应的关键环节。本研究旨在探讨腹股沟白色脂肪组织(iWAT)是否为褐变过程的候选组织。将小鼠置于4℃冷室(冷组)24 h, 23℃常温条件(RT组)。结果显示,与RT组小鼠相比,冷组小鼠iWAT中产热特异性基因,包括过氧化物酶体增殖体激活受体γ辅助激活因子1- α (PGC-1α)和解偶联蛋白1 (UCP1)的mRNA表达明显上调。与此一致的是,米色细胞特异性的跨膜蛋白26 (TMEM26)基因的mRNA表达在低温暴露小鼠的iWAT中也显著高于室温小鼠的iWAT。与对照组相比,冷暴露小鼠iWAT中溶质载体家族27成员1 (SLC27A1)基因的表达有增加的趋势。SLC27A1是编码米色细胞蛋白的另一个基因。然而,这一变化在两组之间没有显著差异。这些数据表明,iWAT是响应冷诱导产热和褐变过程的重要组织。因此,iWAT是进一步研究白色脂肪组织冷诱导产热反应机制的一个有希望的候选者。
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引用次数: 0
Research on some biological indicators of ROC10, ROC23, and ROC26 varieties growing in Hoa Binh province 华平地区ROC10、ROC23和ROC26品种部分生物学指标研究
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0011
Trong Le Van, Khanh Nguyen Nhu, Nga Bui Thi Thuy, Phuong Ha Thi
Analysis of some biochemical indicators during the growth and development of 3 sugarcane varieties ROC10, ROC23, ROC26 is one of the methods contributing to the prequalification of sugarcane varieties with good quality. The results showed that the reducing sugar content in the stems of all three sugarcane varieties decreased with age, of which ROC23 and ROC26 were less than that of ROC10. The sucrose content increased gradually, and ROC23, ROC26 had higher sucrose content than ROC10. The starch content in the cane stem decreased gradually with the age of the plant, of which varieties ROC23, ROC26 were less than ROC10. Vitamin C content of ROC23 variety was higher than that of ROC10 variety in the growing period while ROC26 variety at an early stage, vitamin C content was less than that of ROC10 variety but from 9 months old onwards, it was higher than ROC10 variety. The cellulose content of the ROC23 variety was highest, followed by the ROC10, and the lowest was the ROC26 variety. The results of this study are the scientific basis for selecting sugarcane varieties with good quality based on the biochemical changes of the plant during growth and development.
对3个甘蔗品种ROC10、ROC23、ROC26生长发育过程中的部分生化指标进行分析,是优质甘蔗品种预审的方法之一。结果表明,3个甘蔗品种茎秆中还原糖含量均随年龄增长而降低,其中ROC23和ROC26的还原糖含量低于ROC10;蔗糖含量逐渐升高,ROC23、ROC26的蔗糖含量高于ROC10。甘蔗茎中淀粉含量随植株年龄的增长而逐渐降低,其中ROC23、ROC26品种的淀粉含量低于ROC10。ROC23品种在生育期维生素C含量高于ROC10品种,而ROC26品种在生育期维生素C含量低于ROC10品种,但在9月龄以后维生素C含量高于ROC10品种。纤维素含量最高的品种是ROC23,其次是ROC10,最低的品种是ROC26。研究结果为利用植株生长发育过程中的生化变化选育优质甘蔗品种提供了科学依据。
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引用次数: 0
Some applications of Lagrange interpolation polynomials in practice 拉格朗日插值多项式在实践中的一些应用
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0002
Thuy Nguyen Thu, Ha Le Thi
In this paper, we use Lagrange interpolation method to solve some problems in Agriculture and Health in Vietnam. The data used in this paper are extracted from the data of the General Statistics Office of Vietnam. The Lagrange interpolation method is a good model for forecasting agricultural production as well as the correlation between the number of doctors and the number of hospital beds in medical facilities in Vietnam.
本文利用拉格朗日插值法求解越南农业和卫生领域的一些问题。本文使用的数据摘自越南国家统计局的数据。拉格朗日插值方法是预测越南农业生产以及医生数量与医疗设施病床数量之间相关性的良好模型。
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引用次数: 0
Assessing the difference in the temperature trend in the context of climate change in Bac Giang province 气候变化背景下北江省气温趋势差异评估
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0017
Hung Dao Ngoc, Hang Nguyen Thi, Lieu Nguyen Thi, Luan Nguyen Thanh
Bac Giang is a province in the northern midland and mountainous region of Vietnam. Bac Giang has many potentials and advantages in terms of natural conditions and human resources for economic development. However, climate change has been having a great impact on the socio-economic development of the province. The study applied the correlation assessment method and regression analysis to process temperature data at 4 meteorological stations: Bac Giang, Hiep Hoa, Son Dong, and Luc Ngan. The results demonstrate that in 44 years (1970 - 2014) the trend of change in average temperature is from 0.012 oCyear to 0.018 oCyear. On the other hand, the changing trend of the annual absolute maximum temperature is common at a higher level, from 0.028 oCyear to 0.032 oCyear. The variability of extreme temperature values is much broader than that of the average temperature. The trend of temperature variation (average temperature, annual absolute maximum temperature) is highest in the eastern territory of the province, in mountainous districts including Son Dong, Luc Ngan, and lowest in the western lowland areas namely Hiep Hoa district. The research results will be the assisting tool for management agencies to find solutions to develop socio-economic adaptation to climate change.
北江是越南中部和山区北部的一个省。北江在自然条件和人力资源等方面具有发展经济的潜力和优势。然而,气候变化已经对该省的社会经济发展产生了很大影响。利用相关评价方法和回归分析方法对北江、协和、山东和吕岸4个气象站的气温资料进行了处理。结果表明:44 a(1970—2014)平均气温变化趋势为0.012 oC年~ 0.018 oC年。另一方面,年绝对最高气温的变化趋势在较高的水平上是共同的,从0.028 oC年到0.032 oC年。极端温度值的变率比平均温度的变率大得多。温度变化趋势(平均温度、年绝对最高温度)在该省东部地区最高,在山区包括松东、吕根,在西部低地地区如协和地区最低。研究结果将成为管理机构寻找解决方案的辅助工具,以发展适应气候变化的社会经济。
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引用次数: 0
Elastic deformation and elastic wave velocity of ternary alloys FeCrSi and AuCuSi FeCrSi和AuCuSi三元合金的弹性变形和弹性波速
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0005
Hoc Nguyen Quang, Hien Nguyen Duc, Hoa Nguyen Thi, Uyen Pham Phuong, Ngoc Trinh Hong
The paper uses the model of cubic ternary substitutional and interstitial alloy and conditions in which the interstitial atom concentration is very small compared to the substitutional atom concentration, the substitutional atom concentration is very small compared to the main metal atom concentration. On that basis together with the elastic wave and the elastic deformation theory of this alloy obtained by the statistical moment method, we perform numerical calculations for temperature, pressure, the concentration of substitutional atoms, and concentration of interstitial atoms dependences of the elastic moduli E, K, G, the elastic constants C11, C12, C44, the longitudinal wave velocity Vd and the transverse wave velocity Vn of alloys FeCrSi and AuCuSi. Numerical results for FeCrSi and AuCuSi are compared with that of Fe, FeCr, FeSi, Au, AuCu, AuSi, and other calculations, and experiments. Numerical results for ternary alloys predict experimental results in the future.
本文采用立方三元取代和间隙合金模型,在间隙原子浓度与取代原子浓度相比很小的条件下,取代原子浓度与主金属原子浓度相比很小。在此基础上,结合统计矩法得到的合金弹性波和弹性变形理论,对FeCrSi和AuCuSi合金的弹性模量E、K、G、弹性常数C11、C12、C44、纵波速度Vd和横波速度Vn与温度、压力、取代原子浓度和间隙原子浓度的关系进行了数值计算。将FeCrSi和AuCuSi的数值结果与Fe、FeCr、FeSi、Au、AuCu、AuSi等的计算和实验结果进行了比较。三元合金的数值结果预测了未来的实验结果。
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引用次数: 1
Nutritional status of students at Lao Cai City No. 1 High School, Lao Cai province 老蔡市第一中学学生营养状况调查
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0012
Thu Nguyen Thi Trung, Linh Ha Thuy, Tuyet Le Thi, Dao Duong Thi Anh
An adolescence period (15 - 17 years old) is an important stage of body development. Study on the nutritional status of adolescents plays an important role in health care. A cross-sectional study was conducted on 1095 students aged 15 to 18 years old at Lao Cai No. 1 High School in 2019. Results showed that median age was 16.3; weight was 53 kg; height was 163 cm; waist circumference was 68 cm; hip circumference was 80 cm; BMI was 20.0 kgm2; Z-score height for age was -0.6; Z-score BMI for age was -0.3. Anthropometric indicators such as weight, height, and BMI in boys were higher in girls as compared to boys in all grades. The rates of malnutrition, overweight and obesity were 5.4%, 9.1%, and 1.6%, respectively. The malnutrition, overweight and obesity in boys (6.8%, 3.4%, 2.3%, respectively) were significantly higher in girls (4.1%, 5.8%, 1.1%, respectively) as compared to boys (P < 0.05). These parameters of students of grade 10 (2.5%, 16.4% and 2.5%), 11th grade (6.4%, 7.4% and 2.0%) and 12th grade (6.9%, 3.7% and 0.3%) were different (P < 0.001). The results of the current study showed that the rate of stunted students was 3.9%, however, there were no significant differences in gender and grade level (P > 0.05). These results have oriented students, families, and schools to improve the poor nutritional status, and provide the best conditions for the development of adolescents.
青春期(15 - 17岁)是身体发育的重要阶段。青少年营养状况的研究在卫生保健中具有重要作用。对2019年老蔡一中15 ~ 18岁的1095名学生进行了横断面研究。结果:中位年龄为16.3岁;体重53公斤;身高163厘米;腰围68厘米;臀围80 cm;BMI为20.0 kgm2;年龄Z-score身高为-0.6;年龄的Z-score BMI为-0.3。在所有年级,男孩的体重、身高和身体质量指数等人体测量指标,女孩都高于男孩。营养不良率为5.4%,超重率为9.1%,肥胖率为1.6%。男生营养不良、超重和肥胖发生率分别为6.8%、3.4%和2.3%,女生营养不良、超重和肥胖发生率分别为4.1%、5.8%和1.1%,显著高于男生(P < 0.05)。10年级(2.5%、16.4%和2.5%)、11年级(6.4%、7.4%和2.0%)和12年级(6.9%、3.7%和0.3%)学生的这些参数存在差异(P < 0.001)。本研究结果显示,发育不良学生发生率为3.9%,性别、年级差异无统计学意义(P > 0.05)。这些结果为学生、家庭和学校改善营养不良状况提供了指导,为青少年的发展提供了最佳条件。
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引用次数: 0
Expression analysis of the duplicated genes in the NAC transcription factor gene family related to the drought stress response in peanuts (Arachis hypogaea) 花生干旱胁迫响应相关NAC转录因子基因家族重复基因的表达分析
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0010
H. Tran Thi Thanh, Ha Chu Duc, Khoa Tran Dang, Hong La Viet, Loan Hoang Phuong, Tien Tran Van, Huong Bui Thi Thu, Gioi Dong Huy
NAC has been considered one of the largest transcription factor families in plant species. In peanut (Arachis hypogaea), 29 members of the AhNAC gene family have been identified and characterized. However, the information of their functions related to the mechanism of the stress response has been reported. In this study, a total of seven duplication events, which occurred from the segmental duplication, has been predicted in the AhNAC gene family in peanuts. The KaKs ratios revealed that natural selection prevented the presence of the point mutations in the most duplicated genes, consequently, maintaining their structure and function during evolution. Based on the unrooted phylogenetic tree between AhNAC proteins in peanuts and 23 drought-responsive CaNAC in chickpea (Cicer arietinum), we proposed 12 members of the AhNAC that potentially share similar functions with well-characterized NAC in chickpea. Furthermore, various hormone- and drought-responsive cis-regulatory elements have been found in the promoter regions of these candidate genes. Re-analysis of the previous RNA-Seq demonstrated that the majority of the candidate AhNAC genes were responsive to the osmotic stress. Taken together, our study could provide an important foundation for further functional characterization towards the improvement of stress tolerance in peanuts.
NAC被认为是植物中最大的转录因子家族之一。在花生(Arachis hypogaea)中,已经鉴定并鉴定了29个AhNAC基因家族成员。然而,它们的功能与应激反应机制的相关信息已被报道。本研究共预测了花生AhNAC基因家族中7个由片段重复引起的重复事件。KaKs比值表明,自然选择阻止了大多数重复基因中点突变的存在,从而在进化过程中保持了它们的结构和功能。基于花生AhNAC蛋白与鹰嘴豆(Cicer arietinum) 23个干旱响应CaNAC蛋白之间的无根系统发育树,我们提出了12个与鹰嘴豆NAC具有相似功能的AhNAC成员。此外,在这些候选基因的启动子区域发现了各种激素和干旱响应顺式调控元件。对先前RNA-Seq的重新分析表明,大多数候选AhNAC基因对渗透胁迫有反应。综上所述,本研究可为进一步对花生抗逆性进行功能鉴定提供重要基础。
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引用次数: 0
Selecting and determining the weight of indicators in assessing vulnerability on the agricultural sector in Binh Dinh province due to climate change 在评估平定省农业部门因气候变化而遭受的脆弱性时选择和确定指标的权重
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0014
Thuy Hoang Luu Thu
The purpose of this study is to select and determine the weights of indicators in vulnerability assessment on the agricultural sector in Binh Dinh province by AHP - Analytic Hierarchy Process method with the support of Expert choice software. Indicators with large weights show the role and impact of those indicators in determining the value of the component variables: exposure index (E), sensitive index (S), and adaptive capacity index (AC). The results of the index calculation of the component variables taking into account the weights of the indicators will reflect more objective results when no weights are applied. Analysis of the value of the component index and the vulnerability index shows that: The degree of vulnerability to the agricultural sector in the coastal plain districts and near the sea is greater than that in the mountainous and midland districts. The degree of vulnerability to the agricultural sector of Binh Dinh province is low to very high, of which very high vulnerability is concentrated in coastal districts and near the sea including Hoai Nhon, Phu My, Phu Cat, and Tuy Phuoc districts; high vulnerability in An Lao and Hoai An districts; districts in the southwest of the province have low to moderate levels of vulnerability to the agricultural sector.
本研究的目的是在专家选择软件的支持下,采用层次分析法选择和确定平定省农业部门脆弱性评价指标的权重。权重较大的指标显示了这些指标在确定构成变量的作用和影响:暴露指数(E)、敏感指数(S)和适应能力指数(AC)。在不加权重的情况下,考虑各指标权重的组成变量的指数计算结果更能反映客观的结果。对构成指数和脆弱性指数的数值分析表明:沿海平原地区和临海地区农业部门的脆弱性程度大于山区和中部地区。平定省农业部门的脆弱性程度从低到非常高,其中非常高的脆弱性集中在沿海地区和靠近大海的地区,包括会仁、富美、富吉和图福县;安老和会安地区的脆弱性较高;该省西南部地区对农业部门的脆弱性为低至中等水平。
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引用次数: 0
Diffusion in metals Au, Cu, and interstitial alloys AuSi, CuSi 金属中的扩散:Au, Cu和间隙合金AuSi, CuSi
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0004
Hoc Nguyen Quang, Hien Nguyen Duc, Hoa Nguyen Thi, H. Le Lan, Le Nguyen Ngoc
The paper performs numerically the vacancy activation volume, the activation energy, the pre-exponential factor, and the diffusion coefficient for metals Au, Cu, and alloys AuSi, CuSi in the interval of the concentration of interstitial atoms from zero to 4%, in the interval of temperature from 700 to 1873 K, in the interval of pressure from zero to 180 GPa and the interval of strain from zero to 5%. The paper determines the dependence of the diffusion coefficient on pressure and stress for above mentioned metals and alloys. SMM numerical results show that the Arrhenius law is satisfied for metals and interstitial alloys at different pressures and concentrations of interstitial atoms. SMM numerical results for Au at T = 1000 K and T = 1250 K and at zero pressure are in good agreement with experiments for the activation energy (errors are below 10%) and agree in terms of magnitude for the pre-exponential factor and the diffusion coefficient. SMM numerical results of the diffusion coefficient for Au in the interval of temperature from 977 to 1321 K and for Cu in the interval of temperature from 933.95 to 1336.15 K are compared with experiments and other calculations and there are rather good agreement in terms of magnitude. SMM numerical results of the activation volume of Au and Cu agree well with other calculations. SMM numerical results for diffusion quantities of interstitial alloys AuSi, CuSi in different temperatures, pressures, stresses, and concentrations of interstitial atoms anticipate and orient experiments in the future.
本文对Au、Cu和合金AuSi、CuSi在间隙原子浓度0 ~ 4%区间、温度700 ~ 1873 K区间、压力0 ~ 180 GPa区间和应变0 ~ 5%区间的空位活化体积、活化能、指前因子和扩散系数进行了数值计算。本文确定了上述金属和合金的扩散系数对压力和应力的依赖关系。SMM数值结果表明,在不同压力和不同浓度的间隙原子下,金属和间隙合金均满足Arrhenius定律。在T = 1000 K和T = 1250 K和零压力下,Au的SMM数值结果与实验的活化能(误差小于10%)一致,在指数前因子和扩散系数的大小上也一致。对977 ~ 1321 K范围内Au和933.95 ~ 1336.15 K范围内Cu的扩散系数的SMM数值计算结果与实验和其他计算结果进行了比较,在量级上有较好的一致性。Au和Cu活化体积的SMM数值计算结果与其他计算结果吻合较好。在不同温度、压力、应力和间隙原子浓度条件下,间质合金AuSi、CuSi扩散量的SMM数值结果预测和指导了未来的实验。
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引用次数: 0
A study on drought in Hai Duong province during dry months in the context of climate change 气候变化背景下海阳省旱季干旱研究
Pub Date : 2022-03-01 DOI: 10.18173/2354-1059.2022-0015
Hung Dao Ngoc, Thuy Hoang Luu Thu, Thao Nguyen Duong, Thu Hien Doan Thi
Hai Duong is a province in the Red River Delta with a GDP of 3020 USDyear. Its economy depends heavily on natural conditions, especially in the agricultural sector. In the context of climate change, drought will be a natural disaster that greatly affects the economy - especially agriculture. Using the correlation evaluation method and building complex regression equations, a good correlation was found between the total evaporation with the total monthly rainfall, monthly mean temperature, monthly mean maximum temperature, and monthly minimum temperature. This is the basis for calculating potential future evaporation based on climate change and sea level rise scenarios. Using the method of calculating the drought index K using the input data of climate change and sea level rise scenarios for Vietnam, the study has calculated the drought evolution for the three driest months of the year (12, 1, 2) for the period 2021 - 2050 in Hai Duong province. The results show that with both scenarios RCP 4.5 and RCP 8.5, the drought index is at arid and very arid levels. The drought level in the RCP 8.5 scenario is higher than in the RCP 4.5 scenario, the drought level at Chi Linh meteorological station is 1.4 - 1.5 times higher than the drought level at Hai Duong meteorological station and especially, the drought is cyclical with the scenario RCP 8.5, which shows the maximum every 9 - 10 years.
海阳是红河三角洲的一个省,GDP为3020美元/年。它的经济在很大程度上依赖于自然条件,特别是在农业部门。在气候变化的背景下,干旱将是一种严重影响经济——尤其是农业的自然灾害。利用相关评价方法,建立复回归方程,发现总蒸发量与月总降雨量、月平均气温、月平均最高气温、月最低气温具有良好的相关关系。这是根据气候变化和海平面上升情景计算未来潜在蒸发量的基础。利用越南气候变化和海平面上升情景输入数据计算干旱指数K的方法,计算了2021 - 2050年海阳省3个最干旱月份(12、1、2)的干旱演变。结果表明:在RCP 4.5和RCP 8.5情景下,旱情指数均处于干旱和极干旱水平;RCP 8.5情景的干旱水平高于RCP 4.5情景,池林站的干旱水平是海阳站干旱水平的1.4 ~ 1.5倍,特别是RCP 8.5情景的干旱具有周期性,每9 ~ 10年出现一次高峰。
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引用次数: 0
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Journal of Science Natural Science
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