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Clinical Characteristics and Genomic Profile of Malignant Proliferating Trichilemmal Tumor: A Systematic Review of the Literature. 恶性增生性三叶虫瘤的临床特征和基因组特征:文献系统回顾
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-13 DOI: 10.1002/jso.27925
Noah Hanson, William Farmer, Matthew Andres, Jan Franko, Viet Le

Malignant proliferating trichilemmal tumors (MPTT) are rare skin lesions arising from the outer sheath of the hair follicle root. Because of their rarity and difficulty in pathologic identification, these skin lesions are often initially misdiagnosed. After a literature review, we found initial clinical or histopathological misdiagnosis has an associated 10.4-fold increase in recurrence and 2.18-fold increase in deaths.

恶性增生性三毛细胞瘤(MPTT)是一种罕见的皮肤病变,产生于毛囊根部的外鞘。由于其罕见性和病理鉴定的困难性,这些皮肤病变最初常常被误诊。经过文献回顾,我们发现最初的临床或组织病理学误诊会导致复发率增加 10.4 倍,死亡率增加 2.18 倍。
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引用次数: 0
The Role of Systemic Chemotherapy in Addition to CRS-HIPEC for Colorectal Peritoneal Metastases: Seeking Clarity Amidst Conflicting Evidence. 系统化疗在结直肠腹膜转移瘤 CRS-HIPEC 治疗中的补充作用:在相互矛盾的证据中寻求明确性。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-13 DOI: 10.1002/jso.27961
Ying Yang, Feng Xu
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引用次数: 0
The role of chemotherapy in the management of pancreatic acinar cell carcinoma. 化疗在胰腺尖细胞癌治疗中的作用。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-12 DOI: 10.1002/jso.27834
Kimberly P Woo, Chase J Wehrle, Daphne Remulla, Jenny H Chang, Robert Naples, Daniel Joyce, Robert Simon, Toms Augustin, R Matthew Walsh, Samer A Naffouje

Introduction: Pancreatic acinar cell carcinoma (pACC) is a rare malignancy with unique clinical and molecular features. The role of chemotherapy in pACC management is not well established.

Methods: The National Cancer Database (NCDB) for pACC was used. Cox regression was used in resected pACC patients to identify significant overall survival (OS) predictors. Patients were then divided based on these risk factors into propensity-matched group of surgery versus surgery + chemotherapy and Kaplan-Meier analysis was performed with log-rank tests to compare OS.

Results: The NCDB 2004-2020 included 1592 pACC patients, 1553 were selected. Median age was 66 and 1090 (70.2%) were males. 622 (40.1%) received chemotherapy only, 257 (16.5%) had surgery only, and 365 (23.5%) had both. 189 Patients who received surgery were only matched to peers who had surgery + chemotherapy. The median OS for surgery only was 57.8 ± 6.0 versus 54.2 ± 9.9 months for surgery + chemotherapy (p = 0.836). Cox regression identified nodal and margin status as independent predictors of OS. Therefore, subgroups of patients with node-negative, node-positive, margin-negative, and margin-positive resections were similarly matched 1:1 for the receipt of surgery only versus surgery + chemotherapy. Only patients with node-positive disease had a significant OS benefit with the addition of chemotherapy (44.2 ± 7.3 vs. 27.5 ± 10.5 months; p = 0.036).

Conclusion: Our analysis suggests that surgical resection remains the cornerstone of therapy for pACC. Node status and margin status are the primary prognosticators. The addition of chemotherapy provides an OS benefit only in node-positive disease.

简介胰腺尖细胞癌(pancreatic acinar cell carcinoma,pACC)是一种罕见的恶性肿瘤,具有独特的临床和分子特征。化疗在胰腺尖细胞癌治疗中的作用尚未明确:方法:使用国家癌症数据库(NCDB)中的 pACC 数据。方法:利用国家癌症数据库(NCDB)中的 pACC 数据,对切除的 pACC 患者进行 Cox 回归,以确定重要的总生存期(OS)预测因素。然后根据这些风险因素将患者分为倾向匹配组(手术组和手术+化疗组),并通过对数秩检验进行卡普兰-梅耶尔分析以比较OS:2004-2020 年国家癌症数据库共纳入 1592 例 pACC 患者,其中 1553 例入选。中位年龄为66岁,1090人(70.2%)为男性。622人(40.1%)只接受了化疗,257人(16.5%)只接受了手术,365人(23.5%)同时接受了化疗和手术。189 接受手术的患者只与接受手术+化疗的患者进行配对。仅接受手术治疗的患者的中位生存期为(57.8 ± 6.0)个月,而接受手术+化疗的患者的中位生存期为(54.2 ± 9.9)个月(P = 0.836)。Cox回归确定结节和边缘状态是预测OS的独立因素。因此,在仅接受手术与接受手术+化疗的患者中,结节阴性、结节阳性、边缘阴性和边缘阳性切除术患者亚组进行了类似的1:1配对。只有结节阳性患者在加用化疗后的OS获益显著(44.2 ± 7.3个月 vs. 27.5 ± 10.5个月;p = 0.036):我们的分析表明,手术切除仍是治疗pACC的基石。结节状态和边缘状态是主要的预后指标。只有在结节阳性的情况下,加用化疗才能使患者在手术后的生存期获益。
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引用次数: 0
Preoperative Anemia and Iron Deficiency in Elective Gastrointestinal Cancer Surgery Patients. 胃肠道癌症择期手术患者术前贫血和缺铁。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-12 DOI: 10.1002/jso.27970
Clarissa P Skorupski, Matthew C Cheung, Julie Hallet, Yosuf Kaliwal, Lena Nguyen, Katerina Pavenski, Jesse S Zuckerman, Yulia Lin

Background and objectives: Preoperative anemia can impact postoperative outcomes, but its importance in gastrointestinal cancer patients, and significance of anemia etiology remains unclear. We aimed to characterize the frequency and impact of preoperative anemia, and iron-deficiency anemia (IDA), on perioperative outcomes.

Methods: We performed a retrospective cohort study of adult patients undergoing elective gastrointestinal cancer surgery. The primary outcome was the incidence of perioperative RBC transfusion. Secondary outcomes included 90-day postoperative major morbidity, ICU admission, and 90-day hospital readmission. Multivariable analyses were performed to assess the association between preoperative anemia and IDA and outcomes.

Results: Preoperative anemia was present in 55.5% of patients (n = 15 414), and 58.3% of anemic patients were iron deficient. Preoperative anemia was independently associated with increased risk of RBC transfusion (RR 2.88, 95% CI 2.60-3.20), and secondary outcomes. For every preoperative hemoglobin decrease of 1 g/dL, the adjusted risk of perioperative RBC transfusion increased by 40% (RR 1.39, 95% CI 1.37-1.42).

Conclusion: Preoperative anemia is prevalent, and an independent risk factor for adverse postoperative outcomes. Decreases in preoperative hemoglobin levels elevate the risk of transfusion and adverse outcomes, supporting further study to optimize management of treatable causes of preoperative anemia including IDA.

背景和目的:术前贫血会影响术后效果,但其在胃肠道癌症患者中的重要性以及贫血病因的重要性仍不清楚。我们旨在描述术前贫血和缺铁性贫血(IDA)的频率及其对围手术期预后的影响:我们对接受择期胃肠道癌症手术的成年患者进行了一项回顾性队列研究。主要结果是围手术期输注红细胞的发生率。次要结果包括术后 90 天主要发病率、入住重症监护室和 90 天再入院率。为评估术前贫血和IDA与预后之间的关系,进行了多变量分析:55.5%的患者(n = 15 414)术前存在贫血,58.3%的贫血患者缺铁。术前贫血与输注红细胞的风险增加(RR 2.88,95% CI 2.60-3.20)和次要结果密切相关。术前血红蛋白每下降 1 g/dL,围手术期输注红细胞的调整风险就会增加 40% (RR 1.39,95% CI 1.37-1.42):结论:术前贫血很普遍,是导致术后不良预后的一个独立风险因素。术前血红蛋白水平下降会增加输血和不良预后的风险,因此需要进一步研究,以优化术前贫血的可治疗原因(包括 IDA)的管理。
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引用次数: 0
Lymphaticovenular Anastomosis as a Treatment for Neurogenic Bladder in Patients With Lower Extremity Lymphedema After Gynecologic Cancer Treatment. 淋巴管吻合术治疗妇科癌症治疗后下肢淋巴水肿患者的神经源性膀胱。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-12 DOI: 10.1002/jso.28000
Yukio Seki, Teruhito Okino, Hitoshi Nemoto, Hirofumi Imai, Ryo Karakawa, Akiyoshi Kajikawa, Rintaro Asai, Mayo Tomochika, Tomoyuki Yano

Background and objectives: Neurogenic bladder (NB), a complication of gynecological cancer treatment, entails significant symptoms such as loss of urinary urgency, incontinence, and renal dysfunction. To investigate whether lymphatic fluid stagnation at the pelvis causes NB, we investigated the effectiveness of lymphaticovenular anastomosis (LVA) for NB.

Methods: In this retrospective study between 2014 and April 2024, LVA was performed on 52 patients complaining of preoperative urinary dysfunction with lower extremity lymphedema following pelvic lymphadenectomy in gynecologic cancer treatment. Pre- and postoperative assessments evaluated NB symptoms and volume reduction of lower extremities.

Results: With an average follow-up period of 35.0 months, the volume of the affected limbs was reduced in all patients. Symptoms of urinary function were improved in 44 out of 52 patients, as improved urinary urgency, disappearance of incontinence, and independence from self-catheterization. Among 15 patients who underwent pre- and postoperative questionnaire assessment of NB, the mean score of NB severity decreased significantly from 16.9 ± 7.1 points preoperatively to 4.3 ± 3.6 points postoperatively (p < 0.01).

Conclusions: The specific reason for NB following gynecologic cancer treatment remains unclear. Our study results suggest that lymphatic fluid stagnation itself might be a reason for NB and LVA could reduce these symptoms.

背景和目的:神经源性膀胱(NB)是妇科癌症治疗的一种并发症,具有尿急、尿失禁和肾功能障碍等显著症状。为了探究盆腔淋巴液淤积是否会导致 NB,我们研究了淋巴孔吻合术(LVA)治疗 NB 的效果:在这项2014年至2024年4月的回顾性研究中,我们对52名妇科癌症盆腔淋巴结切除术后出现术前排尿功能障碍和下肢淋巴水肿的患者进行了淋巴-静脉吻合术。术前和术后评估评估了NB症状和下肢体积缩小情况:结果:在平均 35.0 个月的随访期间,所有患者的患肢体积都有所缩小。52 名患者中有 44 人的排尿功能症状得到改善,如尿急症状改善、尿失禁症状消失、可自行导尿等。在接受术前和术后NB问卷评估的15名患者中,NB严重程度的平均得分从术前的16.9±7.1分显著下降到术后的4.3±3.6分(p 结论:术后NB严重程度的平均得分从术前的16.9±7.1分显著下降到术后的4.3±3.6分(p):妇科癌症治疗后出现 NB 的具体原因仍不清楚。我们的研究结果表明,淋巴液淤积本身可能是导致 NB 的原因之一,而 LVA 可以减轻这些症状。
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引用次数: 0
Barriers to Cancer Care in the LGBTQ+ Community. LGBTQ+ 群体癌症护理的障碍。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-11 DOI: 10.1002/jso.27980
Shebiki Beaton, Tamra McKenzie-Johnson

Individuals that identify as lesbian, gay, bisexual, transgender, queer, intersex, and asexual (LGBTQIA) make up a medically underserved population, that experience disparities in cancer care. Specific cancer incidence and mortality in this population is understudied, as national cancer registries and cancer surveys have limited data about sexual orientation or gender identity. The LGBTQIA community face disparate cancer outcomes in prevention, screening, diagnosis, and treatment due to barriers that limit access to cancer care. To better understand these concerns, we will take a deep dive into the three primary barriers that prevent access to cancer care: personal, provider and systems barriers.

被认定为女同性恋、男同性恋、双性恋、变性人、同性恋者、双性人和无性人(LGBTQIA)的人是医疗服务不足的人群,他们在癌症护理方面存在差异。由于国家癌症登记处和癌症调查中有关性取向或性别认同的数据有限,因此对这一人群的具体癌症发病率和死亡率研究不足。LGBTQIA 群体在癌症预防、筛查、诊断和治疗方面面临着不同的结果,这是因为他们在获得癌症治疗方面存在障碍。为了更好地了解这些问题,我们将深入探讨阻碍获得癌症治疗的三个主要障碍:个人障碍、提供者障碍和系统障碍。
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引用次数: 0
Patient-Reported Goals of Care in the Preoperative Clinic: Barriers to and Facilitators of Patient Values Elicitation and Documentation. 术前门诊中患者报告的护理目标:患者价值观征询和记录的障碍与促进因素》。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-11 DOI: 10.1002/jso.27974
Roni Y Rosen, Christan Bartsch, Errika Thompson, Allison Letika-Kreigel, Yashjot Kaur, Susan Ng, Maksim Vaynrub, William E Rosa, Vance Broach, Andrew S Epstein, Judith E Nelson, Garrett M Nash, Deborah Goldfrank

Background and objectives: Infrequent preoperative goals of care (GOC) documentation leads to challenges in medical decision-making when patients experience postoperative complications. We evaluated the feasibility of enhancing GOC documentation through a patient portal-based values questionnaire.

Methods: A patient values questionnaire (PVQ) was distributed to patients before their Gynecologic Surgical Oncology clinic appointments via an electronic health record (EHR)-based portal from June to October 2023. Surgeons and advanced practice providers were encouraged to address PVQ responses during clinic appointments. Patient acceptability surveys were sent to PVQ respondents and clinicians were interviewed to assess feasibility and acceptability.

Results: PVQ response rate was 225/383 (59%); 29% of all patients had an established cancer diagnosis. Clinicians deemed preoperative GOC documentation important and the PVQ valuable to prepare for unexpected postoperative complications. Accessing questionnaire responses through the EHR was a technical barrier. Clinicians agreed that GOC should be addressed after diagnosis and treatment discussions, but before surgery. Ninety percent of patients felt comfortable discussing GOC at their first clinic appointment.

Conclusion: Patient portals facilitate preoperative GOC documentation, however, clarifying and integrating values into care require ongoing discussions between clinicians and patients. Optimal timing of GOC elicitation is posttreatment planning and before surgery when the patient is most informed.

背景和目的:术前护理目标(GOC)记录不频繁导致患者术后出现并发症时医疗决策面临挑战。我们评估了通过基于患者门户网站的价值观问卷加强 GOC 记录的可行性:从 2023 年 6 月到 10 月,我们通过基于电子病历 (EHR) 的门户网站,在妇科肿瘤外科门诊预约前向患者发放了患者价值观问卷 (PVQ)。鼓励外科医生和高级医疗服务提供者在门诊预约期间处理 PVQ 回复。向 PVQ 应答者发送患者接受度调查表,并对临床医生进行访谈,以评估可行性和接受度:PVQ回复率为225/383(59%);29%的患者已确诊癌症。临床医生认为术前GOC记录很重要,PVQ对术后意外并发症的准备很有价值。通过电子病历获取问卷答复是一个技术障碍。临床医生一致认为,应在诊断和治疗讨论之后、手术之前讨论 GOC 问题。90%的患者认为在首次就诊时讨论GOC问题很合适:患者门户网站为术前记录 GOC 提供了便利,但是,临床医生和患者需要不断讨论,才能明确并将价值观融入护理中。最佳的 GOC 激发时机是治疗计划后和手术前,此时患者最了解情况。
{"title":"Patient-Reported Goals of Care in the Preoperative Clinic: Barriers to and Facilitators of Patient Values Elicitation and Documentation.","authors":"Roni Y Rosen, Christan Bartsch, Errika Thompson, Allison Letika-Kreigel, Yashjot Kaur, Susan Ng, Maksim Vaynrub, William E Rosa, Vance Broach, Andrew S Epstein, Judith E Nelson, Garrett M Nash, Deborah Goldfrank","doi":"10.1002/jso.27974","DOIUrl":"https://doi.org/10.1002/jso.27974","url":null,"abstract":"<p><strong>Background and objectives: </strong>Infrequent preoperative goals of care (GOC) documentation leads to challenges in medical decision-making when patients experience postoperative complications. We evaluated the feasibility of enhancing GOC documentation through a patient portal-based values questionnaire.</p><p><strong>Methods: </strong>A patient values questionnaire (PVQ) was distributed to patients before their Gynecologic Surgical Oncology clinic appointments via an electronic health record (EHR)-based portal from June to October 2023. Surgeons and advanced practice providers were encouraged to address PVQ responses during clinic appointments. Patient acceptability surveys were sent to PVQ respondents and clinicians were interviewed to assess feasibility and acceptability.</p><p><strong>Results: </strong>PVQ response rate was 225/383 (59%); 29% of all patients had an established cancer diagnosis. Clinicians deemed preoperative GOC documentation important and the PVQ valuable to prepare for unexpected postoperative complications. Accessing questionnaire responses through the EHR was a technical barrier. Clinicians agreed that GOC should be addressed after diagnosis and treatment discussions, but before surgery. Ninety percent of patients felt comfortable discussing GOC at their first clinic appointment.</p><p><strong>Conclusion: </strong>Patient portals facilitate preoperative GOC documentation, however, clarifying and integrating values into care require ongoing discussions between clinicians and patients. Optimal timing of GOC elicitation is posttreatment planning and before surgery when the patient is most informed.</p>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Debulking Lymphatic Liposuction: Are the Therapeutic Effects Limited to the Treated Limb? 淋巴脂肪抽吸术:治疗效果仅限于治疗的肢体吗?
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-11 DOI: 10.1002/jso.27985
Shih-Lun Lo, Melis Salman, Wei F Chen

Background and objectives: Lymphedema treatment has traditionally focused on region-specific interventions. However, recent evidence suggests otherwise. This study aims to evaluate whether the benefits of liposuction for lymphedema are confined to the treated limb or extend to other areas of the body.

Methods: Patients who underwent liposuction for extremity lymphedema between January and June 2023 at Cleveland Clinic were included in the study. Patients with less than 1-year follow-up or incomplete post-operative tracking studies were excluded. Pre- and post-operative evaluations included patient report, 3D volumetric measurements, and indocyanine green lymphography (ICGL). Liposuction was performed under general anesthesia with circumferential removal of pathological bulk.

Results: Thirty-eight limbs in 36 patients (33 females, 3 males, mean age 58 years) underwent surgery. All reported marked improvements, with some noting the improvements as "life-changing." Improvements in lymphatic functions were observed in all operative limbs (38) and non-operative contralateral limbs (38), with an average volume reduction of 30.0% and 19.5%, respectively. ICGL further confirmed improved lymphatic drainage in all limbs (76).

Conclusions: Liposuction, traditionally considered a region-specific treatment for lymphedema, exerts therapeutic effects beyond the surgical site, suggesting broader systemic benefits.

背景和目的:淋巴水肿治疗历来侧重于针对特定区域的干预措施。然而,最近的证据表明并非如此。本研究旨在评估抽脂治疗淋巴水肿的益处是否仅限于治疗过的肢体,还是会扩展到身体的其他部位:研究对象包括2023年1月至6月期间在克利夫兰诊所接受肢体淋巴水肿吸脂术的患者。随访时间不足1年或术后追踪研究不完整的患者排除在外。术前和术后评估包括患者报告、三维容积测量和吲哚菁绿淋巴造影(ICGL)。抽脂手术在全身麻醉下进行,并对病理肿块进行环形切除:36 名患者(33 名女性,3 名男性,平均年龄 58 岁)的 38 个肢体接受了手术。所有患者都报告说病情明显好转,其中一些人称这种好转 "改变了生活"。所有接受手术的肢体(38 例)和未接受手术的对侧肢体(38 例)的淋巴功能都得到了改善,平均体积分别减少了 30.0% 和 19.5%。ICGL 进一步证实所有肢体的淋巴引流均得到改善(76):结论:传统上认为淋巴水肿吸脂术是一种针对特定区域的淋巴水肿治疗方法,但它的治疗效果超出了手术部位,这表明它具有更广泛的全身性益处。
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引用次数: 0
Active Surveillance for Pleomorphic Adenomas of the Parotid-Tumor Growth Rate, Potential Malignancy, and Surgical Sequalae. 腮腺多形性腺瘤的主动监测--肿瘤生长率、潜在恶性程度和手术机会。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-11 DOI: 10.1002/jso.27977
Helena Levyn, Tejas Subramanian, Alana Eagan, Daniel W Scholfield, Joseph Lopez, Nora Katabi, Richard J Wong, Jatin P Shah, Babak Givi, Luc G T Morris, Ian Ganly, Snehal G Patel

Objective: The outcomes of active surveillance (AS) for pleomorphic adenomas (PA) as an alternative to upfront parotidectomy have not been previously documented in the literature. This cohort study aims to assess the safety and feasibility of AS for parotid gland PA.

Methods: All patients with of previously untreated PA managed between 1990 and 2015 were reviewed. Patients who underwent AS for a minimum of 1 year from the initial consultation were identified. Patient demographics, the reason for AS, tumor growth rate, indication for surgery in those patients eventually operated, final pathology, and surgical sequelae were analyzed.

Results: During the study period, 610 patients with primary PA were treated in our institution. Of whom, 14 (2.3%) underwent AS for a period between 1 and 10 years with a median of 3.73 years (interquartile range [IQR] 1.3-4.9). Patient comorbidities were the most common reason for opting for AS (n = 6, 43%), followed by patients' preference to delay surgery (n = 4, 29%) and older age (n = 2, 14%). The median growth rate was 0.58 mm/year (IQR 0.04, 3.8, range -5.01 to 4.98 mm/year). In patients who eventually underwent parotidectomy (n = 10, 71.4%), the most common reason for intervention was tumor growth (8/10, 80%). Two patients had postsurgical mild transient facial nerve paresis with full recovery, and no carcinomas were discovered on final pathology.

Conclusion: In this selected cohort of patients with PA, the tumor growth rate was lower than traditionally believed. Patients who eventually underwent surgery did not suffer from serious complications and there was no evidence of clinical or pathological malignancy.

目的:作为腮腺切除术的替代方案,主动监测(AS)治疗多形性腺瘤(PA)的效果尚未见文献记载。这项队列研究旨在评估腮腺多形性腺瘤主动监测的安全性和可行性:方法:对1990年至2015年间接受治疗的所有既往未经治疗的PA患者进行回顾性研究。方法:对 1990 年至 2015 年间接受治疗的所有既往未治疗过的 PA 患者进行回顾性研究,确定自初诊起接受 AS 治疗至少 1 年的患者。分析了患者的人口统计学特征、接受强直性脊柱炎治疗的原因、肿瘤生长率、最终手术患者的手术指征、最终病理结果以及手术后遗症:研究期间,我院共收治了 610 名原发性 PA 患者。其中,14 人(2.3%)接受了为期 1-10 年的 AS 治疗,中位数为 3.73 年(四分位数间距 [IQR] 1.3-4.9)。患者的并发症是选择 AS 的最常见原因(6 例,43%),其次是患者希望推迟手术(4 例,29%)和年龄较大(2 例,14%)。中位增长率为 0.58 毫米/年(IQR 0.04,3.8,范围-5.01 至 4.98 毫米/年)。在最终接受腮腺切除术的患者中(n = 10,71.4%),最常见的干预原因是肿瘤生长(8/10,80%)。两名患者术后出现轻度一过性面神经麻痹,但已完全恢复,最终病理检查未发现癌变:结论:在这批经过筛选的 PA 患者中,肿瘤生长率低于传统观点。结论:在这批精选的 PA 患者中,肿瘤生长率低于传统观点,最终接受手术的患者没有出现严重并发症,也没有临床或病理恶性证据。
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引用次数: 0
Comment On: "Prognostic Impact of the Cholangiolar Component in Combined Hepatocellular-Cholangiocarcinoma: Insights From a Western Single-Center Study". 评论:"肝细胞癌-胆管癌合并症中胆管成分的预后影响:一项西方单中心研究的启示"。
IF 2 3区 医学 Q3 ONCOLOGY Pub Date : 2024-11-11 DOI: 10.1002/jso.27995
Liang Peng, Baodi Cao
{"title":"Comment On: \"Prognostic Impact of the Cholangiolar Component in Combined Hepatocellular-Cholangiocarcinoma: Insights From a Western Single-Center Study\".","authors":"Liang Peng, Baodi Cao","doi":"10.1002/jso.27995","DOIUrl":"https://doi.org/10.1002/jso.27995","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Surgical Oncology
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