Journal of the Indian Chemical Society最新文献

{"title":"Chalcone-based bioactive scaffolds: Comparative antioxidant, antibacterial, and anti-Alzheimer activities supported by docking analysis","authors":"Cansu Öztürk ,&nbsp;Songül Bayrak ,&nbsp;Serpil Gerni ,&nbsp;Ufuk Atmaca ,&nbsp;Cetin Bayrak ,&nbsp;Hatice Kızıltaş","doi":"10.1016/j.jics.2026.102435","DOIUrl":"10.1016/j.jics.2026.102435","url":null,"abstract":"<div><div>Chalcone derivatives constitute an important pharmacophore class with a broad spectrum of biological activities, including antibacterial, antifungal, antimutagenic, antitumoral, and anti-inflammatory effects. In this study, the inhibitory potentials of a series of chalcone derivatives against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were comprehensively evaluated through enzyme inhibition assays, antibacterial and antioxidant analyses, and molecular docking simulations. Among the tested derivatives, compound <strong>7</strong> demonstrated the most potent inhibitory activity against AChE (K_i = 4.12 ± 0.84 nM) and BChE (K_i = 6.87 ± 2.61 nM). The molecular docking results further substantiated the in vitro findings, revealing that compound 7 and compound 1 displayed the highest binding affinities toward AChE (−11.3 kcal/mol). In contrast, compound 1 exhibited the strongest interaction with BChE (−9.9 kcal/mol). Detailed interaction mapping showed that compound 7 engages in multiple stabilizing π–π stacking, π–π- alkyl, and hydrogen-bonding interactions with key catalytic residues of AChE, including TRP86, TYR341, TYR337, PHE295, and TRP286, supporting its high inhibitory efficiency. Similarly, the strong BChE affinity of compound 1 was attributed to pronounced π–π stacking interactions with TRP82 and TYR332, highlighting the structural suitability of chalcone scaffolds for cholinesterase binding.</div><div>In addition to its cholinesterase inhibition potential, compound 7 also exhibited superior antioxidant performance, surpassing standard antioxidants in both DPPH (RSE%: 87.43; IC₅₀: 14.57 μM) and ABTS (RSE%: 93.93; IC₅₀: 4.34 μM) assays. Antibacterial screening indicated that the electronic and steric influences of substituent type and position on the chalcone backbone are critical determinants of antibacterial potency. Notably, compounds 1 (zone diameter: 22.13–23.43 mm) and 2 (zone diameter: 22.06–23.06 mm) displayed greater antibacterial effects than the standard reference drug against all tested bacterial strains.</div><div>Overall, the integrated biological, biochemical, and computational results highlight chalcone derivatives, particularly compound 7, as promising multifunctional candidates with therapeutic relevance for diseases associated with cholinergic dysfunction, including Alzheimer's disease, while also offering valuable structural features for the development of antibacterial and antioxidant drugs.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102435"},"PeriodicalIF":3.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative utilization of leather waste for chromium-doped ZnO photocatalysts: Advanced modeling and MATLAB optimization for effective wastewater treatment","authors":"Hadjar Belkacemi ,&nbsp;Amel Benhadji ,&nbsp;Mourad Taleb Ahmed ,&nbsp;Reguia Boudraa ,&nbsp;Hichem Tahraoui ,&nbsp;Abdeltif Amrane ,&nbsp;Mélanie Mignot ,&nbsp;Alain Ledoux","doi":"10.1016/j.jics.2026.102436","DOIUrl":"10.1016/j.jics.2026.102436","url":null,"abstract":"<div><div>This study focuses on the synthesis and characterization of chromium-doped zinc oxide (Zn₀.₉₇Cr₀.₀₃O) photocatalysts derived from recycled leather waste, targeting the photodegradation of Methyl Orange (MO) dye under visible light irradiation. The Zn₀.₉₇Cr₀.₀₃O catalyst was prepared and characterized through X-ray diffraction (XRD), Raman spectroscopy, scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). A comprehensive parametric study was conducted to examine the effects of pH, initial dye concentration, and catalyst dosage on photodegradation performance. Under optimized conditions (pH 6.3, 1 g/L catalyst, 20 ppm dye concentration), the Zn₀.₉₇Cr₀.₀₃O catalyst achieved an 94.8 % degradation efficiency and 87.66 % mineralization within 120 min. Scavengers studies indicate that, photogenerated holes were the most influential species, contributing to a 28 % reduction in degradation efficiency, followed by hydroxyl radicals (30 %) and superoxide radical anions (39 %), while photoelectrons showed the least impact (52 %). The catalyst exhibited high recyclability, maintaining over 82 % efficiency after sixth cycles, demonstrating its robustness. To enhance predictive accuracy of the photocatalytic process, a Gaussian Process Regression (GPR) model coupled with an Improved Lévy Flight Distribution (FDB-LFD) algorithm was employed. This advanced model provided an accurate prediction of the degradation rate, with a predicted value of 95.2810 %, closely aligning with the experimental results (94.8 %), and an error margin of just 1.2810 %. This modeling approach allowed for precise optimization of the process parameters, further showcasing the efficacy of the Zn₀.₉₇Cr₀.₀₃O catalyst in real-world applications. The integration of recycled chromium from leather waste into the ZnO lattice represents a novel approach to sustainable waste valorization and photocatalyst development. The superior photocatalytic performance of Zn₀.₉₇Cr₀.₀₃O under visible light offers a promising solution for the treatment of industrial wastewater, particularly in textile dye removal, while contributing to circular economy objectives.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 3","pages":"Article 102436"},"PeriodicalIF":3.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of graphene and turmeric extract concentration toward photovoltaic efficiency of Dye-Sensitized Solar Cell (DSSC)","authors":"Arief Rahmatulloh,&nbsp;Mutia Devi Hidayati,&nbsp;Refrina Charissadi Firdaus,&nbsp;Shera Angelista Salsha Bella","doi":"10.1016/j.jics.2026.102421","DOIUrl":"10.1016/j.jics.2026.102421","url":null,"abstract":"<div><div>One promising alternative energy source that can replace fossil fuel energy is photon energy derived from sunlight. A device capable of converting this photon energy into electrical power is known as a solar cell, with the Dye-Sensitized Solar Cell (DSSC) representing the third generation of this technology. This research aims to study the performance of turmeric extract as a dye sensitizer and graphene as a counter electrode in DSSC. FTIR characterization is conducted to determine the interaction between the dye sensitizer, TiO₂, and the ITO glass. The appearance of a new absorption at wave number 1500.67 cm⁻¹ shows the interaction between the dye sensitizer, graphene, and TiO₂–ITO glass. In addition, the emergence of absorption at wave numbers 630.74 and 459.07, which represent Ti–O and In–O, respectively, strengthens the interaction between the dye and TiO₂–ITO glass. The interaction between the dye sensitizer, graphene, and TiO₂–ITO glass is also demonstrated by the uniform surface as observed in FESEM topography analysis. The band gap energy between the valence and conduction bands is also analyzed and calculated using UV–Vis spectrophotometry. Further, the presence of graphene in the DSSC reduces the band gap energy from 3.203 to 2.997 eV. While the dye sensitizer significantly reduced the band gap from 3.203 to 2.300 eV. The highest photovoltaic efficiency values of DSSC are obtained with 5 %, %w/v of dye sensitizer and 1 %, %w/v of graphene. The values are 1.66 % in the room and 3.54 % under the sunlight.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102421"},"PeriodicalIF":3.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifunctional SrFe2O4 Nanoparticles: Structural, Optical, and Magnetic Insights with Potent Cytotoxicity Against MCF-7 Breast Cancer Cells","authors":"Manpreet Kaur ,&nbsp;Amanpreet Singh ,&nbsp;Mahipal Singh Sankhla ,&nbsp;Ankush Kumar Tangra","doi":"10.1016/j.jics.2026.102430","DOIUrl":"10.1016/j.jics.2026.102430","url":null,"abstract":"<div><div>Magnetic nanomaterial SrFe₂O₄ with excellent biocompatibility has emerged as a promising candidate for biomedical applications, particularly in cancer diagnostics and therapy. The structural, optical, magnetic, and biocompatible characteristics of the SrFe₂O₄ nanoparticles, which were synthesized by using sol-gel process, were thoroughly examined. The monoclinic crystal structure of the sample, belonging to the P2₁/c:c2 space group, was confirmed by X-ray diffraction (XRD) analysis. Morphological analysis of the syntheized nanoparticle is done by using Transmission electron microscopy (TEM) showed that the nanoparticles possessed a spherical shape, with an average particle size of ∼24 nm. Magnetic measurements confirmed superparamagnetic behaviour at 300 K temperature, with a saturation magnetisation of 43 emu/g. Optical studies complemented structural insights by revealing band gap of ∼2.84 eV which is correlating the crystallinity with the results obtained from TEM and XRD analysis. Furthermore, the SRB assay was used to evaluate biocompatibility in MCF-7 breast cancer cells treated with SrFe₂O₄ nanoparticles, which showed a concentration dependent decrease of cell viability, suggesting low cytotoxicity and favourable interaction with biological systems. These multifunctional properties make SrFe₂O₄ nanoparticles highly attractive for future applications for biomedical applications.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102430"},"PeriodicalIF":3.4,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of biocompatible cinnamon extract loaded carrageenan/polyvinyl alcohol film: Antimicrobial wound dressing for skin infection control","authors":"Mai M. Khalaf ,&nbsp;Mohamed Gouda ,&nbsp;Manal F. Abou Taleb ,&nbsp;Mahmoud A. Abdelaziz ,&nbsp;Hany M. Abd El-Lateef","doi":"10.1016/j.jics.2026.102429","DOIUrl":"10.1016/j.jics.2026.102429","url":null,"abstract":"<div><div>This study aims to evaluate the antimicrobial, antioxidant, and toxicological properties of a biocompatible wound dressing film composed of crude ethanolic cinnamon (CEC) extract- infused carrageenan (CAR)/polyvinyl alcohol (PVA). The CEC showed potent antibacterial activity against <em>Pseudomonas aeruginosa</em> (23 mm inhibition zone) and <em>Acinetobacter baumannii</em> (21 mm). Antioxidant activity results proved the CEC extract's free radical scavenger ability (93 % inhibition). The prepared films demonstrated wider inhibition zones than the CAR/PVA films alone, demonstrating enhanced antimicrobial activity against tested microbes. Furthermore, the inclusion of CEC in CAR/PVA films enhanced the antibacterial activity, achieving a total bacterial log reduction for MRSA and <em>C</em><em>andida</em> <em>albicans</em> within 150 min. The results of the toxicity assessment confirmed that the films were biocompatible, with EC₅₀_% values exceeding 100. The findings of the study confirmed the promise of CEC loaded CAR/PVA films to be used as efficient biocompatible and non-toxic wound dressings.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102429"},"PeriodicalIF":3.4,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of chlorination time and storage conditions on the aging resistance of AgCl electrodes for hyperhidrosis treatment","authors":"Melike Çalık,&nbsp;İlyas Aktaş,&nbsp;Meltem Gör Bölen","doi":"10.1016/j.jics.2026.102427","DOIUrl":"10.1016/j.jics.2026.102427","url":null,"abstract":"<div><div>In this study, AgCl electrodes used in the iontophoresis method to treat hyperhidrosis were produced for different chlorination times of Ag (5,10,15 and 30 min). This study aims to examine the performance of the produced electrodes against aging under two different storage conditions (KCl and NaCl solutions). For this purpose, the effects of aging and storage conditions on the electrodes aged for 5, 15, and 30 days were examined, and the potential differences between the produced electrodes and the reference electrode were measured. According to the results obtained, the electrodes stored in the NaCl solution were found to be more resistant to aging. In addition, the potential difference between these electrodes and the reference electrode was within acceptable limits and showed a high stability. This suggests that NaCl is the most suitable storage condition for the AgCl electrodes. After 5 days of aging in NaCl solution, the AgCl electrode was produced with a chlorination time of 5 min, and the potential difference with the reference electrode was measured as 8.40 mV. The potential difference between the AgCl electrodes produced and aged under the same conditions but stored in KCl solution during the aging period was measured as 100.10 mV. The chlorination times at which the potential difference between the AgCl electrodes and the reference electrode was the lowest were 15 min when stored in the NaCl solution and 30 min when stored in the KCl solution. The findings clarify the design principles of medical-grade electrodes and provide important outcomes for enhancing the reliability and consistency of iontophoresis-based therapies.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102427"},"PeriodicalIF":3.4,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence laws of jump density on Stefan phase change model of thermal dissociation hydrate","authors":"Mingchuan Li ,&nbsp;Shuanshi Fan","doi":"10.1016/j.jics.2026.102418","DOIUrl":"10.1016/j.jics.2026.102418","url":null,"abstract":"<div><div>For a one-dimensional slab hydrate reservoir, a generalized heat-conduction equation with velocity term was built. By solving the uniform divergence equation with a jump density, a Rankine-Hugoniot jump relation in general form was derive in detail. The Stefan's model in cubic form with respect to velocity term coupled at the dissociation interface was established, and the cubic term could often be ignored within the allowable error range of engineering. By substituting mass as a space variable into, and eliminating the velocity term in the heat conduction equation, the Stefan's model with jump density was transformed into a classical Stefan-like's model, and the analytical solution of this model could be obtained successfully. By an example, the influence laws of constant/jump density on the Stefan's model solution were compared and analysed, the temperature distribution and the interface position during the thermal dissociation hydrate were studied. It was discussed that the maximum error due to the jump density was 1.897 %, which was within the allowable error range for engineering applications.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102418"},"PeriodicalIF":3.4,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of biodiesel and fusel oil blends on exhaust gas and particulate emissions in a diesel engine","authors":"Pichitpon Neamyou ,&nbsp;Pomprab Sriumpunpuk ,&nbsp;Jerameth Yodsakul ,&nbsp;Nataphon Phupewkeaw ,&nbsp;Xun Shen ,&nbsp;Punya Promhuad ,&nbsp;Warirat Temwutthikun ,&nbsp;Chanyut Khajorntraidet","doi":"10.1016/j.jics.2026.102431","DOIUrl":"10.1016/j.jics.2026.102431","url":null,"abstract":"<div><div>Fusel oil (FO), an oxygenated by-product of bioethanol fermentation rich in higher alcohols and containing measurable water, is a promising renewable blending component for partial diesel substitution. This study quantifies how FO addition to commercial B7 affects combustion phasing, regulated gaseous emissions, NO/NO₂ speciation, and particle number–size distributions in a stock 2.5-L turbocharged compression-ignition engine under oxygen-rich operation (EGR deactivated). Steady-state tests were conducted at 1200–2000 rpm and 25–75 % load (2000 rpm up to 50 % load) using B7, B7FO10 (10 vol% FO), and B7FO20 (20 vol% FO). In-cylinder pressure (20 cycles, ensemble-averaged) was used to derive apparent heat release rate (HRR). CO, NO, NO₂, NO_x, O₂, and CO₂ were measured using Testo 350 and HC using Horiba MEXA-441ME. Particle number–size distributions (5.6–560 nm) were measured by an EEPS (TSI 3090) under a fixed two-stage dilution protocol (DF₁ = 8, DF₂ = 8; DF total = 64) maintained constant for all fuels and operating points.</div><div>Uniquely, this work simultaneously reports (i) NO/NO₂ partitioning and (ii) particle number–size distributions under a controlled dilution history across a systematic speed–load matrix and links these outcomes to pressure-derived combustion phasing in a stock turbocharged CI engine. FO blending consistently retarded combustion phasing, indicating longer ignition delay and a shift of heat release toward the main combustion stage, most clearly at low speed/load. The largest gaseous-emission penalties occurred at low load (25 % load): relative to B7, CO (≈100–350 ppm) increased by ∼0–30 % for B7FO10 and ∼10–60 % for B7FO20, while HC (≈5–18 ppm) increased by ∼8–100 % and ∼25–125 %, depending on speed. Total NO_x remained broadly comparable to B7 (≈500–1800 ppm; typically, within ±100–300 ppm), whereas FO increased the NO₂ share (NO₂/NO_x ≈ 2–16 %) across the matrix. Particle number increased monotonically with FO fraction and the distribution shifted toward a stronger nucleation-mode contribution (typically ∼7–30 nm), with the maximum total particle concentration reaching 5.6 × 10⁷ cm⁻³ at 2000 rpm and 50 % load for B7FO20 within the tested window. Overall, FO enables partial diesel substitution with limited change in total NO_x but increases ultrafine particle number, highlighting a number–size trade-off that should be evaluated alongside conventional mass-based PM indicators and motivates future chemical characterization of organic-rich nanoparticles.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102431"},"PeriodicalIF":3.4,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative computational design of paracetamol based supramolecular cocrystals: Comparative DFT, surface characterization, docking, and dynamics toward therapeutic applications","authors":"D. Shilpa,&nbsp;K. Vanitha,&nbsp;K. Sadasivam","doi":"10.1016/j.jics.2026.102434","DOIUrl":"10.1016/j.jics.2026.102434","url":null,"abstract":"<div><div>Cocrystals are gaining momentum recent times for the purpose of modulating the physical and chemical properties of the chosen compounds along with the active pharmaceutical ingredient (API) which are dynamically accessible as a drug candidate in various pharmaceutical applications. The formation of heteromolecular H bond plays an important role in the design of the required cocrystal. In this article, three biomolecules such as ethanedioic acid, <em>cis</em>-butenedioic acid and propanedioic acid which are commonly known as oxalic acid (OX), maleic acid (MA) and malonic acid (MAL) are chosen to form cocrystal structures with the API compound tylenol (paracetamol) using quantum computations. Owing to the prompt pharmaceutical desires (antioxidant ability), suitable drug candidate of cocrystals are designed successfully by N–H⋯O and C<img>O⋯H bonding interactions between PA with the foresaid biomolecules, appropriate for effective medicinal approaches by quantum mechanical studies at molecular levels.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102434"},"PeriodicalIF":3.4,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methane adsorption on cobalt-glutamate-based bio-metal-organic-framework for methane storage application","authors":"Awaludin Martin ,&nbsp;Reza Asrian ,&nbsp;Torridho Ricky ,&nbsp;Fayza Yulia ,&nbsp;Kyaw Thu ,&nbsp;Arif Rahman ,&nbsp;Tokumasu Takashi ,&nbsp;N. Nasruddin ,&nbsp;Bianca Natasha Prasetya","doi":"10.1016/j.jics.2026.102432","DOIUrl":"10.1016/j.jics.2026.102432","url":null,"abstract":"<div><div>This study investigates Bio-Metal–Organic Frameworks (Bio-MOFs) based on cobalt-glutamate (Co-Glu) as a potential adsorbent for methane storage, offering insights into sustainable production pathways. The Bio-MOF Co-Glu, synthesized using <span>l</span>-glutamic acid, exhibits promising methane adsorption properties, with a maximum capacity of 0.12 kg/kg at 293 K and 1487 kPa. Although this falls below the U.S. Department of Energy's target of 0.5 kg/kg at 3.5 MPa, the material's favorable enthalpic properties allow for effective thermal management during adsorption, making it a competitive option for practical applications requiring thermal delicacy. The study compares ultrasonic synthesis of Bio-MOF Co-Glu with conventional solvothermal methods, finding that ultrasonic synthesis is more environmentally friendly and energy-efficient. A Cradle-to-Gate Life Cycle Assessment (LCA), conducted using GaBi Sphera and Ecoinvent 3.7, reveals that the production of the cobalt precursor is a major contributor to electricity consumption. However, by integrating renewable energy sources, such as photovoltaics (PV), the process could achieve a 27 % reduction in emissions. Sensitivity analysis suggests further improvements in adsorption performance through doping, ligand modifications, or utilizing mixed-metal frameworks. This work highlights Bio-MOF Co-Glu's potential as a sustainable methane adsorbent, offering pathways for optimization in energy storage applications aligned with green chemistry principles.</div></div>","PeriodicalId":17276,"journal":{"name":"Journal of the Indian Chemical Society","volume":"103 2","pages":"Article 102432"},"PeriodicalIF":3.4,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146023711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}