Journal of the Indian Chemical Society最新文献

A new series of new 4-aminoacetanilide azo derivatives 1–13 were successfully synthesised via a diazo coupling reaction and gave a good to excellent yield of 73 %–93 %. The antioxidant capabilities of the series 1–13 screened through 2,2′-diphenyl-1-picrylhydrazyl (DPPH) assay and ferric reducing antioxidant power (FRAP) assay showed promising data of 12.6–199.4 ppm and 12.65–210.9 mg/ml Trolox equivalent, respectively. The findings supported by in silico docking analysis targeted Heme oxygenase-1 (HO-1) evidenced by a binding score of – 7.2 to – 8.2 kcal/mol outperforming the standard, ascorbic acid scoring only – 5.7 kcal/mol. Among all, compound 11 displayed the highest antioxidant potential with IC₂₅ of 12.6 ppm against DPPH assay and 210.9 mg/ml Trolox for FRAP assay believed owing to the presence of methoxy group at ortho position in the phenolic compound that effectively lowered the ionisation potential and high up energy of highest occupied molecular orbital (HOMO). Nevertheless, the antibacterial potential of the series screened through the Kirby-Bauer disc diffusion method against Escherichia coli and Staphylococcus aureus showed no antibacterial activity postulated due to the presence of amide and acetyl group restricted the ability of the compound to form an interaction with the protein receptor of bacteria tested. This study provided new insight into the development of dual-functional drugs for non-communicable diseases and antimicrobial resistance.

The present study focused on modifying Locust bean gum (LBG) to alter its physical properties, including hydration and cold-water solubility. The chemical modification process for LBG was optimized for scalability by adjusting the reaction medium and mixture of ethanol and water in a ratio of 60:40. The optimized reaction medium had a sufficient amount of water, which allowed the uncoiling of the chains and aided in the scalability of the process. The LBG was subjected to acid modification using various acids with and without the addition of sodium bicarbonate. Results revealed that LBG modified with HCl exhibited enhanced crystallinity, reduced water absorption by 2 folds, reduction in emulsion stability by 20 %, and superior hydrophobicity in comparison to control LBG majorly due to the change in mannose to galactose ratio (9.1:1). On the other hand, the sodium salt of modified LBG exhibited greater amorphousness, increased solubility by 20 %, and a remarkable ∼7-fold increase in surface area. Additionally, there was a ∼5-fold drop in the average pore diameter compared to the control LBG. These results demonstrate the potential for chemical modifications to modify the physical properties of LBG for specific applications.

Our work attempted a green route for provisioning of thallium, lead, and bismuth into cerium oxide nanoparticles (Tl, Pb, and Bi–CeO₂ NP) via the application of Alhagi maurorum. We configured the physicochemical attributes of procured NPs via PXRD, Raman, FESEM/PSA/EDX, and UV–Vis/DRS assessments. Attendance of doped metals in structure of CeO₂ was confirmed by outcomes of PXRD and EDX analyses. Next to the porous morphology, FESEM images also demonstrated the induced alterations in particle size after the doping of different metals. We also tested the photocatalytic function of synthesized NP on Methylene blue (MB) dye on UV light, which displayed the superior degradation functionality of Tl–CeO₂ NP. The toxicity function of synthesized pure and Tl, Pb, and Bi–CeO₂ NP on breast cancer cell (MDA-MB-231) and breast normal cell (MCF-10 A) lines was considered through the results of MTT trial. The outcomes of synthesized NPs displayed no signs of any cytotoxic effects against MCF-10 A and MDA-MB-231 cells, which signified the creation of non-toxic nanoparticles by the introduced doping process. Therefore, we suggest the applicability of our product in drug delivery systems and also industrial implementations similar to dye photodegradation and annihilation of pollution.

We reported synthesis of bis(N-(3-methoxybenzyl)-N-(pyridin-3-ylmethyl)dithiocarbamato-S,S’)M(II) (where M(II) = palladium(II) (1), platinum(II) (2)). Both the complexes were characterized by elemental analysis, FTIR, UV–visible, ¹H and ¹³C NMR spectroscopy. Based on FTIR spectral studies, bidentate coordination of dithiocarbamate ligand was proposed for both complexes. UV–visible spectral data confirm the formation of square planar complexes. The structure properties, frontier molecular orbital (FMO), molecular electrostatic potential (MEP), chemical reactivities and Mulliken charges were investigated using density functional theory (DFT)/B3LYP methods with 6-31+G (d, p) basis sets and LanL2DZ for light atoms and heavy atoms, respectively. FMO and Mulliken charges recognize the chemical active sites of 1 and 2 responsible for its chemical activity. In vitro anticancer activity of complexes 1 and 2 were analyzed on MCF-7 by MTT assay method. Results show that platinum complex 2 has higher activity compared to these of palladium complex 1.

Water pollution is one of the important threats nowadays, to meet the difficulties several studies are being processed. This work aims to improve water quality by breaking dye components from the waste effluents of textile industries. Methylene blue (MB) widely used textile colorant brings several health issues to all living categories aquatic and terrestrial, including humans. All new syntheses of Cerium-doped Titanium dioxide (Ce@TiO₂) nanoparticles have been achieved and proven to be a super-efficient photocatalyst for the photodegradation of MB in wastewater samples. This photocatalyst was prepared using the sol-gel technique without any hazardous chemicals in moderate conditions. The formation of Ce@TiO₂ is confirmed by different characterization using XRD, FTIR, SEM-EDS, and HR-TEM analysis. The photocatalytic efficiency of Ce@TiO₂ photocatalyst is carried out with varying parameters such as pH, contact time, photocatalyst dose, and MB concentration. Ce@TiO₂ is an effective photocatalyst for MB degradation from wastewater at optimized conditions with 92 % removal within 90 min of reaction time. The degradation kinetics follow a pseudo-first-order model, with a rate constant (K) of 0.027min⁻¹, while achieving a remarkable total organic carbon elimination of over 90.0 %. Furthermore, the reusability test showcased the remarkable stability of Ce@TiO₂ over four cycles, with only a minor decline (<8 %) observed in MB degradation efficiency.

The current work deals with the synthesis of polymer modified synthetic clay, composed of Mg–Al layered double hydroxides (LDHs) and using a non-toxic organic polymer polyethylene glycol-400 (PEG400). A series of polymer-composites of Mg–Al LDH (LDHP-400) are prepared by changing concentrations of PEG-400 from 4% to 20 %, to find out the maximum adsorption efficiency for the adsorption of an industrially important anionic azo dye, MO from aqueous. The results depicted that LDH-P400, with 16 % PEG-400 shown the removal efficiency of 99.49 % for 100 ppm solution of MO (20 min). Effect of different factors such as dose of adsorbate, temperature, contact time, and pH of the solution, etc. are systematically investigated using batch experiments and thermodynamics parameters as well as kinetic studies are also carried out for the quick and instantaneous removal of MO from aqueous media. Maximum adsorption capacity of 198 mg/g has been achieved at pH4.2 and at temperature 313K for 100 ppm (mg/l) of MO in aqueous media using 0.5 g/l of adsorbent dose. Desorption studies reveal that prepared LDHP-400 can be reused and recycle up to three successive cycles with achieving 88.23 % recovery of MO, which confirmed that prepared LDHP-400 can be reused effectively for laboratory or industrial wastewater which has MO concentrations up to 100 ppm.

An Asymmetric pseudocapacitor electrodes can achieve higher energy density than carbon-based materials. Ruthenium oxide is the most effective pseudocapacitor material, but it's very expensive and toxic. The use of cerium oxide (CeO₂), which is abundant with good redox properties could be a sustainable alternative for positive electrode. However, CeO₂'s low electronic conductivity limits its performance. To overcome this an asymmetric supercapacitor cell (ASC) was constructed using CeO₂ as the positive electrode and instead of carbon-based materials, MXene (Ti₃C₂T_x) was used as the negative electrode. MXene can deliver better capacitance due to the controllable layer spacing and excellent electronic conduction which can improve the overall conductivity of the ASC. CeO₂//MXene asymmetric cell achieved 122.27 Fg^-1 capacitance with 55.02 Wh Kg⁻¹ energy density, and retained 99.36 % initial capacitance after 10,000 cycles at 20 Ag^-1.

A major environmental issue that contaminates drinking water and endangers human health is nitrate pollution. In this study, goethite, citric acid, tartaric acid was employed to modify Albizia lebbeck seed pod for the biosorption of nitrate ion. The developed unmodified Albizia lebbeck (UALB), citric acid modified Albizia lebbeck (CALB), tartaric acid modified Albizia lebbeck (TALB), and goethite acid modified Albizia lebbeck (GALB) were characterized using scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), and point of zero charge (pH_pzc) to determine the structural morphology, functional group, and adsorbent surface charge. The adsorption nitrate ion onto the biosorbents was found to be dependent on the operating parameters. The findings revealed that the maximum percentage removal of nitrate ion was 80.8 % at pH 7 for UALB, 80.3 % at pH = 4.0 for CALB, 70.30 % at pH = 3.0 for TALB and 76 % at pH 7 for GALB. The adsorption experimental data for nitrate ion adsorption onto ULAB, CALB, TALB, and GALB were best described by the Langmuir isotherm model. The UALB exhibited the highest Langmuir monolayer adsorption capacities with a value of 344.827 mg/g. Therefore, the unmodified form of Albizia lebbeck (UALB) which is economical, and sustainable provides an efficient alternative method for nitrate removal in aqueous environment.