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Internal Hydrocephalus Caused by Coenurus Cerebralis in a Ewe: A Case Report 母羊颅内脑积水1例
Pub Date : 2016-01-01 DOI: 10.5455/jva.19691231041
A. E. A. Sary, K. Hassanein
Objective: Coenurosis is a parasitic disease that particularly affects sheep and goats. The disease is caused by Coenurus cerebralis which is the larval stage of Taenia multiceps. The objective of this study was to investigate the clinical and the pathological lesions caused by C. cerebralis in a ewe. Materials and methods: Two-and-a-half year-old female ewe showing neurological signs was presented to the Veterinary Teaching Hospital, Assiut University, Egypt. Postmortem and histopathological examinations were done to investigate the pathological lessions caused by C. cerebralis. Results: Postmortem examination of the brain revealed Coenurus cyst measuring 5×3 cm associated with dilated lateral ventricle. Histopathological examination revealed extensive areas of liquefactive necrosis in the cerebrum. The necrotic area was infiltrated with lymphocytes, microglia cells and eosinophils. Internal hydrocephalus and atrophy of the ependymal cells of both lateral ventricle and choroid plexus were also seen. Conclusion: It was concluded that coenurosis might be associated with internal hydrocephalus along with some clinical and pathological findings.
目的:长尾尿病是一种寄生虫病,特别影响绵羊和山羊。该病由多头带绦虫的幼虫期脑小绦虫引起。本研究旨在探讨脑棘球蚴对母羊的临床及病理损害。材料和方法:两岁半的母羊出现神经症状,被送到埃及阿西尤特大学兽医教学医院。通过尸检和组织病理学检查,探讨脑棘球蚴引起的病理损害。结果:脑尸检显示脑脊液囊肿,尺寸为5×3 cm,伴侧脑室扩张。组织病理学检查显示大脑内有大面积液化性坏死。坏死区浸润淋巴细胞、小胶质细胞和嗜酸性粒细胞。脑积水,侧脑室室管膜细胞萎缩,脉络膜丛也可见。结论:结合一些临床和病理表现,认为小脑瘫可能与颅内脑积水有关。
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引用次数: 0
Lymphatic Filariasis Baseline Survey in Osun State, Nigeria - 尼日利亚奥孙州淋巴丝虫病基线调查
Pub Date : 2016-01-01 DOI: 10.5455/jva.20160916044926
L. Usip, E. Davies, Y. Saka, B. Okoeguale, E. Nwosu, C. Ityonzughul
The LF Baseline Surveys were carried out in three LGAs (Sentinel Sites) of three Senatorial Districts. These are: Olorunda LGA (Ilie communities) of Osun Central Senatorial District, Ife North LGA (Akinladu community) of Osun East Senatorial District and Ejigbo (Ifeodan community) of Osun West Senatorial district. A total of 967 human blood samples and 931 mosquitoes were collected during the survey in 3 LGAs (Sentinel sites). Blood samples were collected according to WHO prescribed protocol. Thick film method was used for the examination of the mocrofileria. The parasitological result showed microfilaria (mf) prevalence (%) of 1.2 % (Ife North LGA), 1.6% (Olorunda LGA) & 1.6% (Ejigbo LGA). Pyrethrum spray sheet methods was used for collection of mosquitoes. The mosquitoes were identifies and were dissected for prevalent of Wuchereria bancrofti larval stages. The entomological result revealed that out of 931 mosquitoes collected, 725 (77.9%) were Anopheles species, 201 (21.6%) were Culex quinquefasciatus while 10(1.1%) were Mansonia Africana and their prevalence of evections were 17(2.4%), 4(1.9%) and 0(0.0%). Treatment for Onchocerciasis has been ongoing in the past 16 year in Ife north and Olorunda LGAs and 7 years in Ejigbo LGA. The results from the survey have shown that despite the number of years of treatment with ivermectin, LF transmission is ongoing in all endemic LGAs of Osun State. The big challenge of the State health workers is inadequate resources (human, materials & transport) to effectively scale-up treatment in the State. Therefore, it is recommended that the Osun State Ministry of Health collaborates with the relevant Stakeholders to ensure availability of adequate logistics to upscale LF treatment in the State.
基线调查在三个参议院选区的三个哨点进行。它们是:奥松中部参议院区的Olorunda LGA(伊利族社区),奥松东部参议院区的Ife North LGA (Akinladu社区)和奥松西部参议院区的Ejigbo(伊菲丹族社区)。在3个哨点共采集人血967份,蚊虫931只。按照世卫组织规定的程序采集血样。采用厚膜法对微丝蚴进行检查。微丝虫(mf)阳性率分别为1.2% (Ife North LGA)、1.6% (Olorunda LGA)和1.6% (Ejigbo LGA)。蚊虫采集采用除虫菊喷雾片法。对蚊虫进行鉴定和解剖,确定班氏乌切里氏菌幼虫流行期。昆虫学结果显示,共捕获蚊虫931只,按蚊725只(77.9%),致倦库蚊201只(21.6%),非洲曼蚊10只(1.1%),其产卵率分别为17只(2.4%)、4只(1.9%)和0只(0.0%)。在过去16年中,北伊夫州和奥洛伦达州一直在进行盘尾丝虫病治疗,在埃希波州进行了7年治疗。调查结果表明,尽管用伊维菌素治疗多年,但在奥松州所有地方性地方感染中,LF传播仍在继续。国家卫生工作者面临的巨大挑战是资源(人力、物资和运输)不足,无法有效扩大国家的治疗规模。因此,建议奥松州卫生部与相关利益攸关方合作,确保在该州提供足够的后勤保障,以提高LF治疗水平。
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引用次数: 0
PREVALENCE OF GASTROINTESTINAL PARASITES IN PIGS LOCATED IN UMUAHIA, SOUTH - EAST NIGERIA 尼日利亚东南部乌穆阿希亚猪胃肠道寄生虫流行情况
Pub Date : 2016-01-01 DOI: 10.5455/JVA.20161227094149
A. Onyeabor, M. Wosu
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引用次数: 0
Canine Trypanosomosis in the University of Nigeria Veterinary Teaching Hospital (UNVTH), Enugu State, Nigeria, Sub-Saharan Africa - 撒哈拉以南非洲尼日利亚埃努古州尼日利亚大学兽医教学医院(UNVTH)犬锥虫病
Pub Date : 2016-01-01 DOI: 10.5455/JVA.19691231040001
P. U. Umeakuana, B. R. Mohammed, B. Anene
Trypanosomosis is an insect-borne protozoan disease and a serious constraint to livestock production. The incidence of this disease in dogs at the University of Nigeria Veterinary Teaching Hospital (UNNVTH) has not been reported. This study is designed to determine the incidence of canine trypanomosis presented to the (UNNVTH) between June to August, 1998. The incidence of trypanosome species infecting dogs was also determined. Standard trypanosome detection methods comprising of wet blood films, thin films and microhaematocrit centrifugation technique were used; while the degree of anemia was determined through the use of FAMACHA eye color chart and packed cell volume (PCV) values. Results indicate that of the 55 dogs, fifteen (15) were confirmed infected. The highest incidence was recorded in July (54%) whilst those of June and August were 19% each. Of the species of trypanosomes isolated, all but one Trypanososma congelense were Trypanosoma brucei. All the infections were associated with anaemia. There is a significant difference (PKey words: Canine trypanosomosis, dogs, Nigeria, Nsukka, Trypanosoma brucei, Trypanosoma congelense.
锥虫病是一种虫媒原生动物疾病,严重制约着畜牧生产。尼日利亚大学兽医教学医院(UNNVTH)的狗中此病的发病率尚未报告。本研究旨在确定1998年6月至8月期间向UNNVTH提交的犬锥虫病的发病率。同时测定了犬感染锥虫的发生率。采用湿血膜、薄膜和微红细胞压积离心技术等标准的锥虫检测方法;通过FAMACHA眼色图和堆积细胞体积(PCV)值测定贫血程度。结果55只犬中确诊感染15只。7月发病率最高(54%),6月和8月各为19%。分离到的锥虫种中,除1种锥虫外,其余均为布鲁氏锥虫。所有的感染都与贫血有关。关键词:犬锥虫病,犬,尼日利亚,恩苏卡,布鲁氏锥虫,锥虫。
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引用次数: 6
Variation in testicular morphometric traits in Djallonke sheep of North and South ecotypes of Benin and their relationships with body weight and Characteristics 贝宁北部和南部生态型贾伦克羊睾丸形态计量性状的变异及其与体重和性状的关系
Pub Date : 2016-01-01 DOI: 10.5455/JVA.1969123104000011
A. G. Adjibode, G. Koutinhouin, U. Tougan, M. Zannou, C. Hanzen, A. Théwis
The study aims to determine the variability of testicular morphometric traits in Djallonke sheep reared under traditional system in Benin according to the ecotype and their relationships with their body traits. Data were collected from November 2014 to December 2015 on 21 rams of North ecotype and 24 rams of South ecotype of 12 months old. It appears that chest circumference, back width, pelvis length, paired testes weight, testes length, testes diameter, testes volume, testes density, paired epididymal weight, epididymal length, epididymal volume, and the epididymal density depend on ecotype (P˂0.05). The highest chest circumference (69.24 vs 73.29 cm), back width (15.78 vs 14 cm) and pelvis length (23.03 vs 16.8 cm) were recorded in the animals of North ecotype (P˂0.05). similarly, the highest values (P˂0.05) of paired testes weight, testes length, testes diameter, testes volume, testes density, paired epididymal weight, epididymal length, epididymal volume, and the epididymal density were found in rams of North ecotype (respectively of 300.86g, 6.91 cm, 4.82cm, 146.14 ml, 1.02 g/cm3, 27.8 g and 20.1 cm). However, the head length, whither’s height, scapulo-ischium length, scrotal length, scrotal circumference, epididymal volume and the epididymal density were similar among ecotypes and was respectively on average 18.21 cm; 54.64 cm; 60.61 cm; 14.09 cm; 22.17cm; 15.35ml and 0.87g/cm3. In sheep of South ecotype, the live weight was strongly and positively associated with scrotal length, scrotal circumference, paired testes weight, testes length, testes diameter, testes volume, paired epididymal weight, epididymal length and epididymal volume (0.80≤ r ≤0.90; P
本研究旨在根据生态型及其与体性状的关系,确定贝宁传统饲养体系下的贾隆克羊睾丸形态计量性状的变异。2014年11月至2015年12月采集12月龄北方生态型公羊21只,南方生态型公羊24只。胸围、背部宽度、骨盆长度、成对睾丸重量、睾丸长度、睾丸直径、睾丸体积、睾丸密度、成对附睾重量、附睾长度、附睾体积和附睾密度与生态型有关(P值小于0.05)。North生态型动物胸围(69.24 vs 73.29 cm)、背部宽度(15.78 vs 14 cm)和骨盆长度(23.03 vs 16.8 cm)最高(P值小于0.05)。配对睾丸重量、配对睾丸长度、配对睾丸直径、配对睾丸体积、配对睾丸密度、配对附睾重量、配对附睾长度、配对附睾体积、配对附睾密度以北方生态型公羊最高(分别为300.86g、6.91 cm、4.82cm、146.14 ml、1.02 g/cm3、27.8 g和20.1 cm)。不同生态型的头长、头高、肩胛骨长、阴囊长、阴囊围、附睾体积和附睾密度相似,平均为18.21 cm;54.64厘米;60.61厘米;14.09厘米;22.17厘米;15.35ml和0.87g/cm3。南方生态型羊的活重与阴囊长度、阴囊周长、成对睾丸重量、睾丸长度、睾丸直径、睾丸体积、成对附睾重量、附睾长度、附睾体积呈显著正相关(0.80≤r≤0.90;P
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引用次数: 0
Clinical and Hematological Effects of Glyphosate Herbicide on Clarias gariepinus Juvenilles 草甘膦除草剂对小Clarias gariepinus的临床和血液学影响
Pub Date : 2016-01-01 DOI: 10.5455/jva.20160323060011
N. Okwara, G. Ibekwe
Juveniles of Clarias gariepinus were exposed to 0.00mg/l (control) 20mg/l, 40mg/l and 60mg/l of glyphosate solution for 96 hours. Clinical signs were observed and blood was analyzed for hematological parameters such as haemoglobin (Hb), packed cell volume (PCV), white blood cell (WBC), red blood cell (RBC) and its indices: mean corpuscular haemoglobin concentration (MCHC), mean corpuscular haemoglobin (MCH) and mean corpuscular volume (MCV). The results from the study indicated a significant (P
分别用0.00mg/l(对照)、20mg/l、40mg/l和60mg/l草甘膦溶液对加里平Clarias gariepinus幼鱼处理96小时。观察临床体征,分析血液血液学参数,如血红蛋白(Hb)、堆积细胞体积(PCV)、白细胞(WBC)、红细胞(RBC)及其指标:平均红细胞血红蛋白浓度(MCHC)、平均红细胞血红蛋白(MCH)和平均红细胞体积(MCV)。研究结果表明,两组间的差异有显著性(P
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引用次数: 0
Evaluation of Serial Measurements of Selected Biomarkers in Serum and Peritoneal Fluid for the Diagnosis of Intestinal Ischemia in Donkeys: An Experimental Study 评价血清和腹膜液中选定生物标志物的一系列测量对驴肠缺血诊断的实验研究
Pub Date : 2016-01-01 DOI: 10.5455/JVA.1969123104000010
Y. Hamad, M. El-Ashker, H. Ibrahim, K. Abouelnasr, M. Youssef
Up to now, there has been limited evidence relating to the early diagnostic approach of colic in equine patients. The purpose of this study was to evaluate serial measurements of selected biomarkers in both serum and peritoneal fluid (PF) in donkeys underwent experimental intestinal obstruction owing to early detection of intestinal. For this purpose, four apparently healthy male donkeys (Equus asinus) were randomly purchased based on their health condition and were thoroughly examined to rule out concurrent or even previous ailments. Following a standard pre-surgical and surgical precautions, these animals were subjected to intestinal ischemia via complete ligation of ileum and its mesentery. The animals were clinically and ultrasonographically monitored for 72 hours. Paired samples of blood and PF were collected from each animal before surgery (T0) and following surgical intervention at the following time points: T12, T24, T48 and T72 to measure the respective levels of L-lactate, nitric oxide (NO), total alkaline phosphatase (TAP), lipase and cardiac troponin I (CTnI). The results herein demonstrated that the pattern of both PF and blood lactate were significantly higher at T72 than those at other time points (P< 0.05). Serum values of NO, AP, lipase and CTnI, despite being not significantly changed among the different time points, their respective levels in the PF were altered significantly when compared with their levels in serum (P
到目前为止,有关马绞痛患者的早期诊断方法的证据有限。本研究的目的是评估早期发现的实验性肠梗阻驴血清和腹膜液(PF)中选定的生物标志物的一系列测量结果。为此,研究人员根据健康状况随机购买了4头明显健康的公驴(Equus asinus),并对其进行了彻底检查,以排除并发或甚至以前的疾病。按照标准的术前和手术预防措施,这些动物通过完全结扎回肠及其肠系膜进行肠缺血。对这些动物进行临床和超声监测72小时。分别于术前(T0)和术后(T12、T24、T48、T72)采集各组动物的成对血液和PF样本,分别测定l -乳酸、一氧化氮(NO)、总碱性磷酸酶(TAP)、脂肪酶和心肌肌钙蛋白I (CTnI)的水平。结果表明,T72时PF和血乳酸水平均显著高于其他时间点(P< 0.05)。血清NO、AP、脂肪酶和CTnI值虽然在不同时间点间变化不显著,但其在PF中的水平与血清中的水平相比有显著变化(P
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引用次数: 0
Clinicopathological and Bacteriological Studies on Pneumonia in Camel (Camelus dromedarius) 骆驼肺炎的临床病理及细菌学研究
Pub Date : 2016-01-01 DOI: 10.5455/JVA.20160409123446
S. Nahed, E. Tarek, H. Amani, E. Iman, D. Asmaa
This study aimed to isolate the most common bacterial pathogens causing respiratory diseases in camel in addition to studying the hematological, biochemical and histopathological changes associated with the disease. Forty apparently healthy she-camels and 60 respiratory-distressed cases were used in this study. Nasopharyngeal swabs and blood and tissue samples were collected from both groups. The results implicated that Klebsiella pneumonia and Staphylococcus aureus were the most common bacterial pathogens isolated from both healthy and diseased animals. Hematological parameters showed a significant decrease in red cell parameters and a significant increase in total leukocytic counts in the diseased group. Significant decreases were observed in serum concentrations of albumin, calcium, inorganic phosphorus, sodium and chloride, whereas a significant increase were seen in serum levels of total protein, globulin, urea, creatinine, potassium and activities of hepatic enzymes. There was a significant decrease in blood pH and Po2 and a significant increase in Pco2 and bicarbonate levels in the pneumonic animals. The main histopathological alterations included chronic bronchitis, lung fibrosis and interstitial pneumonia. We can conclude that Klebsiella pneumonia and Staphylococcus aureus appeared to be the main bacterial causes of pneumonia in camel. The disease is associated with significant hematological, and biochemical alterations which upon understanding can provide a good knowledge of the pathogenesis and thus controlling the condition in camel.Key words: Acid-base status, bacteriology, Camelus dromedarius, clinical pathology, pneumonia.
本研究旨在分离引起骆驼呼吸道疾病最常见的细菌病原体,并研究与该疾病相关的血液学、生化和组织病理学变化。本研究选用40只表面健康的母骆驼和60只呼吸窘迫的母骆驼。两组均采集鼻咽拭子、血液和组织样本。结果表明,肺炎克雷伯菌和金黄色葡萄球菌是从健康和患病动物中分离出的最常见的细菌病原体。血液学参数显示病变组红细胞参数明显下降,白细胞总数明显增加。血清白蛋白、钙、无机磷、钠和氯化物浓度显著降低,血清总蛋白、球蛋白、尿素、肌酐、钾和肝酶活性显著升高。肺炎动物的血液pH值和Po2显著降低,二氧化碳分压和碳酸氢盐水平显著升高。主要病理改变为慢性支气管炎、肺纤维化和间质性肺炎。由此可见,肺炎克雷伯菌和金黄色葡萄球菌是引起骆驼肺炎的主要细菌。该疾病与显著的血液学和生化改变有关,一旦了解,就可以很好地了解发病机制,从而控制骆驼的病情。关键词:酸碱状态,细菌学,骆驼,临床病理,肺炎
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引用次数: 4
Preliminary Study on the Contractile Effects of the Aqueous Extract of Leptadenia Hastata Leaf (Pers Decne) on Rat Uterus 荆芥叶水提物对大鼠子宫收缩作用的初步研究
Pub Date : 2016-01-01 DOI: 10.5455/jva.20160323055939
I. J. Omeh, I. D. Peter, V. Maina, U. Sandabe, A. William, P. Mshelia, G. Egwu
The effect of the aqueous leaf extract of Leptadenia hastata on the contractile activity of the female uterus in rats was studied. The aqueous leaf extract was extracted with distilled water using a Soxhlet extractor and this yielded 24.1% w/w of the extract. The phytochemical study of Leptadenia hastata leaf was also determined and this revealed the presence of alkaloids, tannins, anthraquinones, phlobatannins, saponins, cardiac glycosides, flavonoids, carbohydrates and terpenoids. The uterus of seven adult intact/non-pregnant virgin female rats were isolated and the effect of the extract on rat uterus was studied and measured on a kymograph. Uterine contractile activity was demonstrated by different doses of the extract. The results also show that the extract increases the length of uterine segments. It was thus concluded that the aqueous leaf extract of Leptadenia hastata has uterotonic principles which could be responsible for the oxytocic effects on the uterus and could therefore be used as an ecbolic. The identification of this phytochemical constituent would certainly be the focus of future studies.
研究了虎爪藤叶水提物对大鼠雌性子宫收缩活性的影响。用索氏提取器用蒸馏水提取叶片水提物,提取率为24.1%。同时,还测定了其植物化学成分,发现其主要成分有生物碱、单宁、蒽醌、酞菁、皂苷、心苷、黄酮类化合物、碳水化合物和萜类化合物。以7只未怀孕的成年雌性大鼠为实验对象,研究了提取物对子宫的影响。子宫收缩活动表现为不同剂量的提取物。结果还表明,该提取物增加了子宫段的长度。综上所述,细叶水提物具有促子宫作用,可作为促子宫剂使用。这种植物化学成分的鉴定肯定是未来研究的重点。
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引用次数: 2
Evaluation of the Protective Effects of Savliv Drops in CCL4- Induced Hepatic Fibrosis Albino Rats - Savliv滴剂对CCL4诱导的白化大鼠肝纤维化保护作用的评价
Pub Date : 2016-01-01 DOI: 10.5455/JVA.20150903025602
F. Ashour, F. A. Alnagar, S. Treesh, Walid M. Husien, M. A. Alssaie, M. A. Alkholi
Savliv® suspension, is an herbal drug for liver cirrhosis treatment developed by Indian scientists, used to prevent the liver fibrosis induced by carbon tetrachloride (CCL4) in male albino rats. This study provides further evidence on its role as a hepato-therapeutic agent in the experimental rats with CCL4 -induced liver fibrosis. Then Liver tissue and serum were collected. Oral administration of savliv®) drops (750 and 500µl /rat) after CCL4-fibrosis induction showed a significant decrease in the collagen fibre formation and cell membrane destruction. Histopathological examination revealed the regression of collagen fiber and connective tissues percentage between the liver lobules in the CCL4- induced liver fibrotic rats (G4&5) and reconstruction - regeneration of the damaged liver cells after treated rats (G4&5) with savliv drops (750 and 500µl /rat) at week 8, in a dose dependent manner. The serum levels of Glutamic-Oxaloacetic Transaminase (GOT), Glutamic Pyruvic Transaminase (GPT), and alkaline phosphatse (ALP) enzymes were significantly increased in the CCL4-model group in comparison with the control groups (oil: vehicle). Treatment with savliv® drops showed a marked reduction in the above condition. These results further support that the Savliv® drops has the potency of curative effects for liver fibrotic cells induced by toxic agent.
Savliv®悬浮液,是印度科学家开发的治疗肝硬化的中草药,用于预防四氯化碳(CCL4)引起的雄性白化大鼠肝纤维化。本研究进一步证明了其作为肝治疗剂在CCL4诱导的肝纤维化实验大鼠中的作用。然后采集肝组织和血清。ccl4纤维化诱导后口服savliv®滴剂(750和500µl /大鼠)可显著减少胶原纤维形成和细胞膜破坏。组织病理学检查显示,CCL4诱导的肝纤维化大鼠(G4&5)在第8周用savliv滴剂(750和500 μ l /大鼠)处理大鼠(G4&5)后,肝小叶间胶原纤维和结缔组织百分比下降,受损肝细胞重建-再生,并呈剂量依赖性。ccl4模型组大鼠血清谷草转氨酶(GOT)、谷丙转氨酶(GPT)、碱性磷酸酶(ALP)水平较对照组(油:对照)显著升高。用savliv®滴剂治疗可显著减轻上述症状。这些结果进一步支持了Savliv®滴剂对毒性物质诱导的肝纤维化细胞具有治疗作用。
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引用次数: 1
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Journal of Veterinary Advances
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