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Chemical Profiling, Larvicidal Activity and Antihemolytic Property of Allium sativum L. and Allium cepa L. Essential Oil 葱和葱精油的化学特性、杀幼虫活性和抗溶血性能
Pub Date : 2021-09-20 DOI: 10.51201/JUSST/21/09622
P. Durgadevi, P. Sumathi
Essential oils are plant derived concentrates of the secondary metabolites responsible for the aromatic flavor attributing to its various medicinal properties. Fresh Allium sativum ( A. sativum ) and Allium cepa ( A. cepa ) were subjected to steam distillation for isolation of essential oil characterized by performing Gas Chromatography – Mass Spectroscopy (GC-MS). Chromatogram of the essential oil depicted the presence diallyl sulfide (5.35%), 2-(2’-carbamoylphenoxy)-butanoic acid (2.64%), 2-ethyl-5-methylthiophene (0.42%), diallyl disulphide (18.76%), 3-(2-thia-4-pentenyl)-1-thia-cyclohex-5-ene (1.09%) and dimethyl tetrasulphide (0.15%), 2,4-Thiazolidinedione (0.01%), 5-chloro-2-hydroxy-1,3-dinitrobenzene (5.93%), 6-Methoxy-1-methyl-3,4-dihydroisoquinoline (47.91%) in A. sativum and A.cepa respectively. Larvicidal activity against third instar larvae of Anopheles stephensi ( A. Stephensi ) was assessed by following the standard protocol of World Health Organization. The 50% lethality (LC 50 ) of A. stephensi larvae was observed at 265.96 ± 1.88 ppm and 357.14 ± 2.36 ppm of A. sativum and A. cepa essential oil correspondingly. The mortality rate of the larvae was both time and dose dependent. Besides, the in vitro antihemolytic activity of the essential oil was also assessed using Sheep erythrocytes. The erythrocyte lysis was inhibited by the essential oils of both A. sativum and A. cepa in a concentration dependent manner with an IC 50 of 427.35 ± 1.23 µl and 549.45 ± 1.38 µl respectively. On a comparative assessment between the essential oils of A. sativum and A. cepa , the former exhibited better larvicidal activity against the disease-causing vector, A. stephensi . Still, both could serve as potent insecticidal agents after further identification of the responsible chemical compound and its mode of action.
精油是植物衍生的次生代谢物的浓缩物,由于其各种药用特性而产生芳香风味。采用水蒸气蒸馏法分离新鲜大蒜(Allium sativum)和洋葱(Allium cepa)精油,采用气相色谱-质谱联用技术对其进行了表征。香精油色谱分析表明,香精油中分别含有二烯丙基硫化物(5.35%)、2-(2′-氨基甲氧基苯氧基)丁酸(2.64%)、2-乙基-5-甲基噻吩(0.42%)、二烯丙基二硫化物(18.76%)、3-(2-硫-4-戊基)-1-硫-环己-5-烯(1.09%)和二甲基四硫化物(0.15%)、2,4-噻唑烷二酮(0.01%)、5-氯-2-羟基-1,3-二硝基苯(5.93%)、6-甲氧基-1-甲基-3,4-二氢异喹啉(47.91%)。采用世界卫生组织的标准方案,对施氏按蚊三龄幼虫进行了杀幼虫活性评价。苜蓿挥发油浓度为265.96±1.88 ppm,苜蓿挥发油浓度为357.14±2.36 ppm,对斯蒂芬氏夜蛾幼虫的50%致死率(lc50)分别为50%和50%。幼虫的死亡率有时间依赖性和剂量依赖性。此外,还利用绵羊红细胞对其体外抗溶血活性进行了评价。两种精油对红细胞溶解均有抑制作用,其抑制效应均呈浓度依赖性,ic50分别为427.35±1.23µl和549.45±1.38µl。通过对沙芥精油和cepa精油的对比分析,发现沙芥精油具有较好的杀虫活性。尽管如此,在进一步确定其化学成分及其作用方式后,两者都可以作为有效的杀虫剂。
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引用次数: 0
Comparative study between sprayed and inhaled nebulized lidocaine for suppression of hemodynamic response to laryngoscopy and oral endotracheal intubation 雾化与吸入利多卡因抑制喉镜及气管插管血流动力学反应的比较研究
Pub Date : 2021-09-18 DOI: 10.51201/JUSST/21/09599
Ahmed A. Ahmed, Hasan Sarhan Haider, F.I.C.M.S A Ic Consultant anesthetist.
Background: Direct laryngoscopic manipulation and endotracheal intubation are noxious stimuli capable of producing hemodynamic changes characterized by tachycardia, hypertension, and arrhythmias. Which are tolerated in normotensive healthy individuals but had greater impact in patients with cardiovascular and cerebrovascular diseases lead to increased morbidity and mortality. Aim of the study: To compare the efficacy of sprayed and inhaled nebulized lidocaine in suppressing the cardiovascular response to laryngoscopy and tracheal intubation in normotensive patients undergoing general anesthesia. Patient and method: 80 adult patients undergoing elective surgery under general anesthesia with endotracheal intubation were randomly allocated into two equal groups. Patients in nebulized lidocaine (NL) group received pre-induction nebulized (1ml of 10%) lidocaine, while those in sprayed lidocaine (SL) group received pre-induction sprayed (10 puffs of 10%) lidocaine. The general anesthesia technique was standardized for the two groups. The primary outcome measures were hemodynamic response at 1, 3, 6, 9, and 12 min after intubation. The secondary outcome measures were to note down any adverse effects associated with drugs. The statistical package used was SPSS version 25. Results: There was a statistically significant difference ( P < 0.05) between nebulizes and sprayed lidocaine in heart rate, systolic, diastolic and mean arterial pressures at different time points after tracheal intubation with nebulized lidocaine being most effective and better toleration. Conclusion: The hemodynamic instability was lesser with nebulized lidocaine as compared to sprayed lidocaine. The effect was on heart rate and blood pressure. Use of nebulized lidocaine is simple, safe, effective and better patient acceptance.
背景:直接喉镜操作和气管插管是能够产生以心动过速、高血压和心律失常为特征的血流动力学改变的有害刺激。它在血压正常的健康人中是耐受的,但对心脑血管疾病患者的影响更大,导致发病率和死亡率增加。目的:比较雾化利多卡因和雾化吸入利多卡因对正常血压全麻患者喉镜和气管插管时心血管反应的抑制效果。患者与方法:80例经气管插管全麻择期手术的成人患者随机分为两组。雾化利多卡因组(NL)给予诱导前雾化(10%)利多卡因1ml,雾化利多卡因组(SL)给予诱导前雾化(10次,10%)利多卡因。两组均采用标准化的全身麻醉技术。主要结局指标是插管后1、3、6、9和12分钟的血流动力学反应。次要结局指标是记录与药物相关的任何不良反应。统计软件包为SPSS 25。结果:雾化利多卡因与雾化利多卡因在气管插管后不同时间点的心率、收缩压、舒张压及平均动脉压比较,差异均有统计学意义(P < 0.05),雾化利多卡因效果最好,耐受性较好。结论:雾化利多卡因与雾化利多卡因相比,血流动力学不稳定性较低。这对心率和血压有影响。雾化使用利多卡因简便、安全、有效,患者接受度较高。
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引用次数: 0
New Estimator for AR (1) Model with Missing Observations 缺失观测值AR(1)模型的新估计
Pub Date : 2021-09-06 DOI: 10.51201/JUSST/21/09521
M. Issa
: In this paper, new form of the parameters of AR(1) with constant term with missing observations has been derived by using Ordinary Least Squares (OLS) method, Also, the properties of OLS estimator are discussed, moreover, an extension of Youssef [18]has been suggested for AR(1) with constant with missing observations. A comparative study between (OLS), Yule-Walker (YW) and modification of the ordinary least squares (MOLS) is considered in the case of stationary and near unit root time series, using Monte Carlo simulation.
本文利用普通最小二乘(OLS)方法,导出了AR(1)的参数的新形式,讨论了OLS估计量的性质,并对AR(1)提出了Youssef[18]对AR(1)的推广。采用蒙特卡罗模拟方法,对平稳和近单位根时间序列的(OLS)、Yule-Walker (YW)和修正的普通最小二乘(MOLS)进行了比较研究。
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引用次数: 0
Cloud Infrastructure Automation Tools: A Review 云基础设施自动化工具:综述
Pub Date : 2021-06-17 DOI: 10.51201/JUSST/21/05397
Nishchal Shetty, H. Krishnappa
Many businesses have moved their services to the cloud throughout the years. One of the main reasons for this is its less expensive infrastructure and scalability. The necessity for infrastructure automation develops as a result of the increased usage of the cloud. There are multiple cloud automation tools available but there is no single tool suitable for every situation. This paper summarizes the various features offered by the different types of cloud automation tools.
多年来,许多企业已经将他们的服务转移到云端。其主要原因之一是其较便宜的基础设施和可伸缩性。由于云的使用增加,基础设施自动化的必要性也随之增加。有多种可用的云自动化工具,但没有一种工具适合每种情况。本文总结了不同类型的云自动化工具提供的各种功能。
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引用次数: 0
Surgical and clinical aspects of colorectal carcinoma and their correlation with BRAFV600E expression in Iraqi patients 伊拉克患者结直肠癌的外科和临床方面及其与BRAFV600E表达的相关性
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05271
Suroor Abdulkareem Tarkan, Iraq. environment, I. Mohammed, Dr.Thaeer Jawad Kadhim, Baghdad Iraq. environment
background:Colorectal cancer (CRC) the most common gastrointestinal cancer in the world . In Iraq it's fifth of the 5 commonest cancer between male 6.33% and fourth of commonest cancer in between female 4.35% .Co-morbidity ,mortality and the prognosis depended on several factors like age, gender ,stage , grade ,general health of patient , although the stage and grade are the most important factors . That is why different types and modality of diagnostic tools and methods had been liberated to the field of such a serious disease to altering it's progression. The oncogenic mutation in the kinase region of BRAF gene result in abnormal cellular growth , apoptosis ,resistance , tumor progression and metastasis.Objects /To high light on surgical and clinical criteria of colonic tumorsand specially focus on CRC in Iraqi patients .Alsoto analyses the efficacy of use immunohistochemical expression of BRAFV600E biomarker in colorectal tissues of Iraqi patients.Material and Methods/ In this study , a total of 90patients of colonic tumor referring to Al-Yarmouk Teaching Hospital ,all investigations done for them clinical ,laboratory , radiology and endoscopic with biopsy were done to them. Then after all cases with CRC (60 patients) under gone surgery each case according to standard surgical technique he needed and specimen send to histopathological examination , form each case 2 slides was done at a private lab. One For H&E stain and , second one for IHC.Results/In our study the CRC is more common in old age , males , left colon and most cases of high grade (III) and high stage (III and IV) and more than 5cm. The current study shown a correlation of BRAF Journal of University of Shanghai for Science and Technology ISSN: 1007-6735 Volume 23, Issue 6, June 2021 Page -345 expression with age, tumor size , tumor grade and stage of CRC patients is significant value , but with other variables are not significant correlation in CRC pateints.conclucion /According to our result most of the CRC cases occurs in the 7th decade of life and most of the cases were stage 3 tumor . We found significant correlation between BRAF expression and patient's age, tumor site , tumor size , pathological stage and histological grade. Key words/Colorectal cancer (CRC), BRAF and immunohistochemistry ( IHC)
背景:结直肠癌(Colorectal cancer, CRC)是世界上最常见的胃肠道肿瘤。在伊拉克,它在男性最常见的5种癌症中排名第五(6.33%),在女性最常见的癌症中排名第四(4.35%)。共发病、死亡率和预后取决于几个因素,如年龄、性别、分期、分级、患者的一般健康状况,尽管分期和分级是最重要的因素。这就是为什么不同类型和方式的诊断工具和方法被解放到这种严重疾病的领域,以改变它的进展。BRAF基因激酶区域的致癌突变导致细胞异常生长、凋亡、耐药、肿瘤进展和转移。目的:探讨伊拉克结直肠癌患者的外科及临床诊断标准,分析BRAFV600E生物标志物在伊拉克结直肠组织中的免疫组化表达效果。材料和方法:本研究共纳入Al-Yarmouk教学医院的90例结肠肿瘤患者,对他们进行临床、实验室、放射学和内镜活检检查。所有结直肠癌患者(60例)均行手术后,每例患者均按自己需要的标准手术技术,标本送组织病理检查,在私人实验室做2张载玻片。一个用于hiv染色,第二个用于免疫组化。结果/在我们的研究中,结直肠癌多见于老年、男性、左结肠,多数为高分级(III)和高分期(III和IV)及大于5cm。目前的研究显示BRAF在上海理工大学学报ISSN: 1007-6735 vol . 23, Issue 6, June 2021 Page -345表达与CRC患者的年龄、肿瘤大小、肿瘤分级和分期有显著的相关性,但与其他变量在CRC患者中无显著相关性。结论/根据我们的研究结果,大多数结直肠癌病例发生在生命的第70年,大多数病例为3期肿瘤。我们发现BRAF表达与患者年龄、肿瘤部位、肿瘤大小、病理分期和组织学分级有显著相关性。关键词:结直肠癌,BRAF,免疫组化
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引用次数: 0
A Study of Novel Optical Character Recognition Algorithms 新型光学字符识别算法的研究
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05265
Roshan Suvaris, S. Sathyanarayana
The Optical Character Recognition has been the inseparable part of human life during everyday transaction. The OCR has extended its application areas in almost all fields viz. healthcare, finance, banking, entertainment, trading system, digital storage and so on. In the recent past, handwriting recognition is one of the hardeststudy areas in the area of image processing. In this paper the various techniques for converting textual content from number plates, printed, handwritten paper document into machine code have been discussed. The transforming method used in all these techniques is known as OCR. The English OCR system is necessary for the conversion of various published books and other documents in English into human editable computer text files. Latest researches in this area have included the methodologies thatidentify different fonts and styles of English hand written scripts. As of date, even though a number of algorithms are available, it has its own pros and cons. Since, recognition of different styles and fonts in machine printed and handwritten English script is a biggest challenge, this field is open for the researchers to implement new algorithms that would overcome the deficiencies of its predecessors. KeywordsOCR, neural network, segmentation, hidden markov, fuzzy logic
在日常交易中,光学字符识别已经成为人类生活中不可分割的一部分。OCR的应用领域已扩展到医疗、金融、银行、娱乐、交易系统、数字存储等几乎所有领域。近年来,手写识别一直是图像处理领域的研究热点之一。本文讨论了将车牌、印刷、手写纸质文件的文本内容转换为机器代码的各种技术。在所有这些技术中使用的转换方法被称为OCR。英语OCR系统是将各种已出版的英文书籍和其他文档转换为人类可编辑的计算机文本文件所必需的。该领域的最新研究包括识别不同字体和风格的英语手写脚本的方法。到目前为止,尽管有许多算法可用,但它有自己的优点和缺点。由于在机器打印和手写的英语脚本中识别不同的风格和字体是一个最大的挑战,因此该领域对研究人员开放,以实现新的算法,以克服其前辈的不足。关键词socr,神经网络,分割,隐马尔可夫,模糊逻辑
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引用次数: 0
Scenario of Biomedical Waste Management during COVID-19 Pandemic in Delhi, India 2019冠状病毒病大流行期间印度德里生物医学废物管理情景
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05266
Divyanshu Aneja, Anshul Rana, A. Kumari, Anunay A. Gour
The COVID-19 pandemic has resulted in a significant rise in the production of biomedical waste in India's healthcare waste management system. Authorities in Delhi are finding it increasingly difficult to maintain and treat large volumes of biomedical waste as the volume of biomedical waste continues to rise.In addition to the COVID19-related biomedical waste to segregate and dispose of, a huge strain has been imposed on the health-care management system.This research examines the current state of biomedical waste management in Delhi, India as well as the past and present state of biomedical waste generation in various hospitals of Delhi. In this study, the five private hospitals of Delhi have been taken and the data is taken from their websites respectively. The duration of Waste generation has been taken from the year 2016-2020 for each hospital which has been represented graphically. This paper also covers the quantification of biomedical waste ofDelhi and India from June 2020 to December 2020, highlighting thecomparative analysis of the top 5 States of India producing the largest amount of biomedical waste presented graphically. Apart from that, the study covers the current legal status of biomedical waste management in India (Latest Guidelines and Amendments in BMW Rules, 2016 by Central Pollution Control Board for managing COVID-19 based medical wastes) as well as various advances in treatment technologies for handling large amounts of COVID-19 BMW.The consequences of biomedical waste, which can pose a significant threat to both humans and the environment, have also been addressed. Similarly, various effective measures and latest treatment technologies have been listed in the sense of proper waste management in a holistic manner toward a sustainable future. This research will help officials and other organisations ensure that there is no inefficiency in the system and that all activities are carried out efficiently.
2019冠状病毒病大流行导致印度医疗废物管理系统中生物医学废物的产生量大幅增加。随着生物医学废物的数量不断增加,德里当局发现越来越难以维持和处理大量生物医学废物。除了需要隔离和处置与covid - 19相关的生物医学废物外,卫生保健管理系统也面临巨大压力。本研究考察了印度德里生物医学废物管理的现状,以及德里各医院生物医学废物产生的过去和现在的状况。在本研究中,选取了德里的五家私立医院,数据分别取自其网站。每个医院的废物产生时间从2016-2020年开始计算,并以图形形式表示。本文还介绍了2020年6月至2020年12月期间德里和印度生物医学废物的量化情况,重点介绍了对印度产生最多生物医学废物的前5个邦的比较分析。除此之外,该研究还涵盖了印度生物医学废物管理的当前法律状况(中央污染控制委员会2016年关于管理基于COVID-19的医疗废物的最新指南和宝马规则修正案),以及处理大量COVID-19宝马的处理技术的各种进展。生物医学废物可能对人类和环境构成重大威胁,其后果也已得到处理。同样,我们也列出了各种有效的措施和最新的处理技术,以整体方式妥善管理废物,迈向可持续发展的未来。这项研究将有助于官员和其他组织确保系统中没有效率低下,所有活动都有效地进行。
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引用次数: 4
Data Quality Analysis based Machine Learning models for Credit Card Fraud Detection 基于数据质量分析的信用卡欺诈检测机器学习模型
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05263
Amit Pundir, Rajesh Pandey
Misrepresentation of money is a developing issue in monetary business with far-reaching consequences and keeping in mind that many processes have been found. A data quality management with data mining has been effectively applied to data sets to mechanize the investigation of massive amounts of complex information. Data mining has likewise played a notable role in identifying credit card fraud in online exchanges. Fraud detection in credit card is a data quality management issue that considered under data mining, tested for two important reasons — first, the profiles of ordinary and false practices habitually change, and also because of the explanation that charge card fraud information is exceptionally slow. This research paper examines the performance of Decision Trees, Logistics Regression, and Random Forest relies strategically on profoundly skewed credit card fraud data. The dataset of credit card transaction is sourced from Kaggle (a publically accessible dataset repository) with 284,807 transactions. These methods are applied to raw data values and data preprocessing techniques. Assessment of the performance of techniques depends on accuracy, sensitivity, specificity, precision, and recall. Results indicate the optimal accuracy for the decision trees, logistics regression, and random forest classifiers with 90.8%, 98.5%, and 99.1% respectively.
货币的虚假陈述是货币业务中一个发展中的问题,具有深远的影响,并记住许多过程已经被发现。基于数据挖掘的数据质量管理有效地应用于数据集,实现了对海量复杂信息的机械化调查。数据挖掘同样在识别在线交易中的信用卡欺诈方面发挥了显著作用。信用卡欺诈检测是数据挖掘下考虑的一个数据质量管理问题,测试有两个重要原因:一是普通和虚假行为的特征会习惯性地变化,二是签账卡欺诈信息异常缓慢的解释。这篇研究论文考察了决策树、物流回归和随机森林的性能,这些算法在策略上依赖于严重偏斜的信用卡欺诈数据。信用卡事务数据集来源于Kaggle(一个可公开访问的数据集存储库),其中包含284,807个事务。这些方法应用于原始数据值和数据预处理技术。技术性能的评估取决于准确性、敏感性、特异性、精密度和召回率。结果表明,决策树、logistic回归和随机森林分类器的最佳准确率分别为90.8%、98.5%和99.1%。
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引用次数: 0
Metacognitive Proactive Hybrid Learning Model Using ICT Tools 基于ICT工具的元认知主动混合学习模型
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05270
Dr. Kendaganna Swamy S, Dr. Subramanya K N, Prof. Shruthi. P, Dr. Ramaa A
Many aspects characterized novelty. In both practical and theoretical regards, the difficulties observed in technical education are addressed from the psycho-cognitive and the psycho-pedagogical point of view. The modern education system slowly adapts itself to the most powerful educational tools such as Web-based learning, problem-based learning, and collaborative learning methods. Still, they have their scope and limitations, such as difficulty in integrating online and offline, lack of an assessment tool for quality assurance, etc. Hence, the research work's objective was to develop a Metacognitive Hybrid Model (MHM) for enhancement of the transformative potential of outcome-based, blended learning in the higher technical institutions. The MHM model consists of both full-fledged online as well as conventional classroom instructions. Hence, the proposed MHM is highly effective and an efficient model to improve the basic knowledge of the heterogeneous student community and improve their technical knowledge and progression rate. The analysis of the proposed model's results was computed based on C.O. (Course Outcomes) attainments, grading statistics, and the success rate. The research results show that the success rate of students who adopted the MHM improved by ~8% compared to conventional teaching methods. MHM increases Course Outcome-1 and Course Outcome-2 by 18% and 9%, respectively, which leads to the improvement of basic understanding and application of technology. A minimal impact on Course Outcome-3 and Course Outcome-4 was observed, which is less than 6% due to an increase in the design aspects of the respective courses that were adopted. MHM has been progressively recognized as one of the essential components for the faculties to nurture their students in an Outcome-Based Education (OBE) System
许多方面都具有新颖性。在实践和理论方面,从心理认知和心理教学的角度来解决技术教育中观察到的困难。现代教育系统慢慢地适应最强大的教育工具,如基于网络的学习、基于问题的学习和协作学习方法。尽管如此,它们仍有其范围和局限性,例如难以整合线上和线下,缺乏质量保证的评估工具等。因此,研究工作的目标是开发一种元认知混合模型(MHM),以增强高等技术院校基于结果的混合学习的变革潜力。MHM模式既包括完整的在线教学,也包括传统的课堂教学。因此,所提出的MHM是一个非常有效的模型,可以提高异质学生群体的基础知识,提高他们的技术知识和进步率。对所提出模型结果的分析是基于C.O.(课程成果)成绩、评分统计和成功率进行计算的。研究结果表明,与传统教学方法相比,采用MHM的学生的成功率提高了约8%。MHM使课程成果-1和课程成果-2分别提高了18%和9%,从而提高了对技术的基本理解和应用。对课程结果3和课程结果4的影响最小,由于所采用的课程设计方面的增加,影响小于6%。MHM已逐渐被认可为学院培养学生的成果导向型教育(OBE)系统的重要组成部分之一
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引用次数: 1
Does Solfinacin solve the urgency symptoms in postpartum women ? 索尔非那星能解决产后妇女的急症症状吗?
Pub Date : 2021-06-07 DOI: 10.51201/JUSST/21/05248
Anwar Khazal Jafar, Baghdad Iraq. environment, E. M. Shihab, Lewaa Arkan Jabar, I. Ahmed, MSc. pharmacology
Background: It is widely accepted that antimuscarinics are considered first-line treatment for patients with overactive bladder (OAB). However, the mechanism by which antimuscarinics improve the symptoms of OAB remains to be fully elucidated.Patients and methods: This study is a clinical prospective follow up study carried out in Consultancy Clinic of Al-Elwiya Maternity Teaching Hospital in Baghdad-Iraq. duration(November, 2019-April, 2020). inclusion criteria were adult postpartum women at childbearing age with symptoms of overactive bladder treated by Gynecologist with Solifenacin tablets. Results:current study showed 34% of them were in age group 20-29 years. Mean parity history of women with OAB was (3); 32% of them had parity history of 1-3 para and 68% of them had parity history of 4-6 para. delivery mode for 84% of women with OAB was vaginal delivery, as well as 36% of women with OAB had ≤7 times of urinations at day, as well as a significant decline in score 2 observed after treatment with Solifenacin (p=0.01). No significant differences were observed in score 3 before and after Solifenacin treatment (p=0.06). A significant decline in score 4 was observed after treatment with Solifenacin (p=0.001). No significant differences were observed in women with OAB before and after Solifenacin treatment, soa highly significant increase in control of urination after treatment (p<0.001). Conclusion: solifenacin drug is effective in reduction of overactive bladder syndrome score three months after treatment. Journal of University of Shanghai for Science and Technology ISSN: 1007-6735 Volume 23, Issue 6, June 2021 Page -375 keywords:solifenacin ,overactive bladder syndrome , after treatment. ةصلاخلا ةذبن ناك .ىودع دوجو مدع عم لوبلا سلسو لوبتلا ةرثكو يلوبلا حاحللإاب اًیریرس ةناثملا طاشن طرف زیمتت : .اھتایح ةیعونو ةأرملا ةحص ىلع ریبك ءبع طاشنلا ةطرفملا ةناثملل ةساردلا فدھ طاشن طرف ضارعأ نم نوناعی نیذلا ةدلاولا دعب تاغلابلا ءاسنلل نیسانیفیلوس جلاع ةیلاعف مییقت : .ةناثملا ثحبلا قرطو ىضرملا يمیلعتلا ةیولعلا ىفشتسمل ةیراشتسلاا ةدایعلا يف تیرجأ ةیریرس ةیلبقتسم ةعباتم ةسارد : نم ةرتفلا لاوط رھشأ ةتس للاخ قارعلا دادغب يف ةموملأل 1 ربمفون 2019 ىتح 30 لیربأ 2020 ةنیع ىلع نم 50 دمتعی نیسانیفیلوس جلاع مییقت ناك .نیسانیفیلوسب ةجلاعملا ةناثملا طاشن طرف عم ةدلاولا دعب ةغلاب ةأرمأ .جلاعلا دعبو لبق ةناثملا طاشن طرف ضارعأ جئاتن سایق ىلع ا جئاتنل ) نیسانیفیلوسلا جلاع لبق ةناثملا طاشن طرف ضارعأ رایعم ةجیتن لیجست مت : (7.6 جلاعلا دعب ) ىلإ نیسانیفیلوسـب 5.6 ) امھنیب ریبكوزیمتم يئاصحا قرف دوجو عم ( P <0.001 ـل جلاعلا رمتسا .( 84 نم ٪ ـل فقوت امنیب ، ةطرفملا ةناثملاب تاباصملا ءاسنلا 16 ـل جلاعلل ةدیج ةباجتسا تظحولو .نھنم ٪ 88 ءاسنلا نم ٪ ـل ةفیعض ةباجتسا تظحول امنیب ، طاشنلا ةطرفملا ةناثملاب تاباصملا 12 جلاعل ةیبناج راثآ تظحول .نھنم ٪ يف نیسانیفیلوس 16 ، مفلا فافج ةعئاشلا ةیبناجلا راثلآا تناك .طاشنلا ةطرفملا ةناثملاب تاباصملا ءاسنلا نم ٪ .ةیؤرلا حوضو مدعو ، كاسملإاو تاجاتنتسلاا ةمزلاتمب تاباصملا ءاسنلا جلاع يف نمآو لاعف ءاود وھ نیسانیفیلوسلا نیراكسملل داضملا لماعلا : .ةناثم
背景:抗毒蕈素被广泛认为是膀胱过动症(OAB)患者的一线治疗方法。然而,抗蛇毒素改善OAB症状的机制仍未完全阐明。患者与方法:本研究是在伊拉克巴格达Al-Elwiya妇产教学医院会诊门诊进行的临床前瞻性随访研究。时间:2019年11月- 2020年4月。纳入标准为经妇科医生使用索利那新片治疗的有膀胱过动症状的育龄成年产后妇女。结果:目前的研究显示,其中34%的人年龄在20-29岁之间。OAB女性平均产次史为(3);有1 ~ 3段胎次史的占32%,有4 ~ 6段胎次史的占68%。分娩方式为阴道分娩的OAB女性占84%,日排尿次数≤7次的OAB女性占36%,经索利那新治疗后2分明显下降(p=0.01)。索利那新治疗前后3分差异无统计学意义(p=0.06)。索利那新治疗后4分明显下降(p=0.001)。索利那新治疗前后OAB患者排尿控制率无显著性差异,但治疗后排尿控制率显著增高(p<0.001)。结论:索利那星治疗后3个月可有效降低膀胱过度活动综合征患者的评分。上海理工大学学报ISSN: 1007-6735卷23,第6期,2021年6月页-375关键词:索利那新,膀胱过度活动综合征,治疗后。ةصلاخلاةذبنناك。ىودعدوجومدععملوبلاسلسولوبتلاةرثكويلوبلاحاحللإاباًیریرسةناثملاطاشنطرفزیمتت:。اھتایحةیعونوةأرملاةحصىلعریبكءبعطاشنلاةطرفملاةناثمللةساردلافدھطاشنطرفضارعأنمنوناعینیذلاةدلاولادعبتاغلابلاءاسنللنیسانیفیلوسجلاعةیلاعفمییقت:。ةناثملاثحبلاقرطوىضرملايمیلعتلاةیولعلاىفشتسملةیراشتسلااةدایعلايفتیرجأةیریرسةیلبقتسمةعباتمةسارد:نمةرتفلالاوطرھشأةتسللاخقارعلادادغبيفةموملأل1ربمفون2019ىتح30لیرب2020ةأنیعىلعنم50دمتعینیسانیفیلوسجلاعمییقتنانك。یسانیفیلوسبةجلاعملاةناثملاطاشنطرفعمةدلاولادعبةغلابةأرمأ。جلاعلادعبولبقةناثملاطاشنطرفضارعأجئاتنسایقىلعاجئاتنل)نیسانیفیلوسلاجلاعلبقةناثملاطاشنطرفضارعأرایعمةجیتنلیجستمت:(7.6جلاعلادعب)ىلإنیسانیفیلوسـب5.6)امھنیبریبكوزیمتميئاصحاقرفدوجوعم(P < 0.001ـلجلاعلارمتسا。(84نم٪ـلفقوتامنیب،ةطرفملاةناثملابتاباصملاءاسنلا16ـلجلاعللةدیجةباجتساتظحولو。نھنم٪88ءاسنلانم٪ـلةفیعضةباجتساتظحولامنیب،طاشنلاةطرفملاةناثملابتاباصملا12جلاعلةیبناجراثآتظحول。نھنم٪يفنیسانیفیلوس16،مفلافافجةعئاشلاةیبناجلاراثلآاتناك。طاشنلاةطرفملاةناثملابتاباصملاءاسنلانم٪。ةیؤرلاحوضومدعو،كاسملإاوتاجاتنتسلااةمزلاتمبتاباصملاءاسنلاجلاعيفنمآولاعفءاودوھنیسانیفیلوسلانیراكسمللداضملالماعلا:。ةناثملاطاشنطرف:ةیحاتفملاتاملكلانیسانیفیلوس,。ةناثملاطاشنطرفةمزلاتمرھشاثلاثدعبجلاعلا
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