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Hand Osteoarthritis and Subclinical Cardiovascular Disease in Middle-Aged Women. 中年女性手部骨关节炎与亚临床心血管疾病
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1089/jwh.2023.1088
Rodrigo Rafael Flores-Marinelarena, Tatiana Sofia Rodríguez-Reyna, Carlos Cantú-Brito, Martín Lajous, Mario H Flores-Torres, Valeria Valaguez-Moreno, Carlos Eduardo Herrera-Venegas, Andres Catzin-Kuhlmann

Objective: To determine subclinical cardiovascular disease (sCVD) in middle-aged women with clinically manifested hand osteoarthritis (HOA) and to improve the characterization of cardiovascular risk in this population. Design: We cross-sectionally evaluated the relationship between HOA and sCVD in 1,803 volunteers from the Mexican Teachers' Cohort. From 2012 to 2016, a subsample from Mexico City, the Northern state Nuevo León, and the Southern states Chiapas and Yucatán was invited for clinical evaluations, during which neurologists examined carotid arteries using ultrasound, and a standardized HOA questionnaire was also administered. HOA was defined as age ≥45 years, hand joint pain, and morning stiffness that lasted no longer than 30 minutes. sCVD was assessed using the intima-media thickness (IMT) and atherosclerotic plaques. Results: Among participants with a mean age of 51 years (±4), 18.4% met the criteria for HOA, and the prevalence of carotid atherosclerosis was 23.1%. After multivariable adjustment, women diagnosed with HOA had a 1.8% (95% confidence interval [CI] 0.3, 3.3) greater mean IMT than those without this joint disease. Similarly, women with HOA had 36% (95% CI 1.01, 1.84) higher odds of carotid atherosclerosis. Conclusions: HOA is associated with sCVD in middle-aged women. This relationship might be due to low-grade chronic inflammation; however, further research is required to clarify the underlying mechanisms.

目的确定临床表现为手部骨关节炎(HOA)的中年女性的亚临床心血管疾病(sCVD),并改善该人群的心血管风险特征。设计:我们横向评估了墨西哥教师队列中 1803 名志愿者的 HOA 与心血管疾病之间的关系。从 2012 年到 2016 年,我们邀请了墨西哥城、北部新莱昂州、南部恰帕斯州和尤卡坦州的部分志愿者进行了临床评估,期间神经科医生使用超声波检查了颈动脉,并进行了标准化的 HOA 问卷调查。HOA的定义是年龄≥45岁、手部关节疼痛、晨僵持续时间不超过30分钟。结果显示在平均年龄为 51 岁(±4)的参与者中,18.4% 的人符合 HOA 标准,颈动脉粥样硬化的患病率为 23.1%。经多变量调整后,确诊患有 HOA 的女性的平均内径比未患这种关节疾病的女性高 1.8%(95% 置信区间 [CI] 0.3,3.3)。同样,患有 HOA 的女性患颈动脉粥样硬化的几率要高出 36% (95% CI 1.01, 1.84)。结论:HOA 与心血管疾病有关:HOA与中年女性的心血管疾病有关。这种关系可能是由于低度慢性炎症造成的;然而,还需要进一步的研究来阐明其潜在机制。
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引用次数: 0
Should I Stay, or Should I Go? Emotional Exhaustion's Association with Intent to Leave in a National Sample of Female Physician Trainees. 我该留,还是该走?全国女实习医生样本中情感枯竭与离职意向的关联。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-30 DOI: 10.1089/jwh.2024.0470
Tyra Fainstad, Adrienne Mann, Lila Steinberg, Maria A Woodward, Ami Shah

Background: Physician burnout disproportionately affects women and contributes to attrition from the workforce, a costly problem that likely begins in training. Female physicians leave the workforce significantly earlier than male counterparts. The association between burnout and attrition intent in women physician trainees is unknown. Methods: This is a cross-sectional analysis of baseline data from a national sample of female physician trainees in a randomized controlled trial testing a well-being program in 2022. Participants completed surveys on burnout and intent to leave. Associations were analyzed using chi-square testing and univariable linear regression. Results: A total of 1,017 trainees responded. The average standard deviation (SD) age was 30.8 (4.0) years, 959 (94.3%) self-identified as a woman, and 540 (53.1%) as White. One-fifth (207, 20.7%) were in postgraduate year (PGY)-1, 198 (19.8%) PGY-2, and 595 (59.5%) ≥ PGY-3. Most scored positively for burnout; 77.5% experienced high emotional exhaustion (EE). One-fifth (20.6%) reported some intent to leave their program before graduation, and 32.7% reported intent to leave their specialty within 2 years. There was a strong association between EE scores and intent to leave: trainees reporting a high likelihood to leave before graduation had a 22.27 higher EE point average than those reporting no likelihood (95% confidence interval [CI]: 7.80, 36.74, p = 0.003). Conclusions: Attrition intent was associated with burnout. Addressing burnout during training will not only benefit trainees but could impact the retention of women physicians.

背景:医生的职业倦怠对女性的影响尤为严重,并会导致自然减员,这个代价高昂的问题很可能始于培训。女医师离职的时间明显早于男医师。女实习医师的职业倦怠与自然减员意向之间的关系尚不清楚。方法:这是一项横断面分析,研究对象是 2022 年一项随机对照试验中的全国女实习医师样本,该试验测试了一项福利计划。参与者完成了关于职业倦怠和离职意向的调查。采用卡方检验和单变量线性回归分析了两者之间的关联。结果如下共有 1,017 名学员做出了回复。平均标准差 (SD) 年龄为 30.8 (4.0) 岁,959 人 (94.3%) 自认为是女性,540 人 (53.1%) 自认为是白人。五分之一(207 人,占 20.7%)处于研究生年级 (PGY)-1,198 人(占 19.8%)处于研究生年级-2,595 人(占 59.5%)≥研究生年级-3。大多数人在职业倦怠方面得到了积极的评分;77.5%的人经历了高度的情感衰竭(EE)。五分之一(20.6%)的人表示有意在毕业前离开他们的专业,32.7%的人表示有意在两年内离开他们的专业。EE 分数与离职意向之间存在密切联系:报告很有可能在毕业前离职的学员的平均 EE 分数比没有这种可能性的学员高出 22.27 分(95% 置信区间 [CI]:7.80, 36.74, p = 0.003)。结论:自然减员意向与职业倦怠有关。在培训期间解决职业倦怠问题不仅能使学员受益,还能影响女医生的留任。
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引用次数: 0
A Review for Clinical Practice in the Treatment and Prevention of Recurrent Urinary Tract Infections in Women over Age 65. 治疗和预防 65 岁以上女性复发性尿路感染临床实践综述》。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-23 DOI: 10.1089/jwh.2023.0987
Helen Query, Ashley Carroll, Adam P Klausner, Linda S Burkett

Urinary tract infection (UTI) is a pervasive, costly, and dangerous cause of morbidity and mortality worldwide, which can lead to further complications if they become recurrent or progress to urosepsis. Recurrent UTI is a particular concern among postmenopausal females because of increased risk factors and decreased estrogen levels, leading to changes in the urogenital epithelium and subsequently causing alterations in the urogenital microbiome. Prevention strategies for recurrent UTIs are often incorporated into patient-centered care plans, but finding the right management can be difficult for older women since many of the common treatment options have contraindications and adverse side effects. This review aims to describe the diagnosis, treatment, and special considerations for the treatment and prevention of recurrent UTIs in women over 65. Current prevention strategies include both antibiotic and nonantibiotic options. The antibiotic choice for older women presents a few unique challenges, including frequent allergy or intolerance of side effects, renal or liver dysfunction, and polypharmacy or drug interactions. Nonantibiotic options range from readily accessible drugstore remedies to experimental vaccines, which all are accompanied by certain advantages and disadvantages. Appropriate management plans can help to reduce symptoms and poor outcomes among older females. In addition, we hope future studies continue to investigate the proper dosing and routes for optimal management in this aging female population.

尿路感染(UTI)是全球发病率和死亡率的一个普遍、昂贵和危险的原因,如果反复发作或发展为尿毒症,会导致更多并发症。绝经后女性的风险因素增加,雌激素水平下降,导致泌尿生殖道上皮发生变化,进而引起泌尿生殖道微生物组的改变,因此复发性UTI尤其令人担忧。复发性尿路感染的预防策略通常被纳入以患者为中心的护理计划中,但对于老年妇女来说,找到正确的治疗方法可能比较困难,因为许多常见的治疗方案都有禁忌症和不良副作用。本综述旨在介绍 65 岁以上女性复发性尿路感染的诊断、治疗以及治疗和预防的特别注意事项。目前的预防策略包括抗生素和非抗生素两种选择。老年妇女在选择抗生素时面临一些独特的挑战,包括经常过敏或不耐受副作用、肾功能或肝功能不全、多药或药物相互作用。非抗生素的选择范围很广,从药店容易买到的药到实验性疫苗,它们都有一定的优缺点。适当的管理计划有助于减少老年女性的症状和不良后果。此外,我们希望未来的研究能继续探究对这一高龄女性群体进行最佳管理的正确剂量和途径。
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引用次数: 0
From Healing to Hurting: Addressing Sex- and Gender-Based Differences in Chronic Postsurgical Pain. 从治愈到伤害:解决手术后慢性疼痛的性别差异。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-23 DOI: 10.1089/jwh.2024.0701
Lopa Misra, Suneela Vegunta, Tarrah A Folley
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引用次数: 0
Women Have Arrived in Medicine: Successful Institutions Will Adapt. 女性已进入医学界:成功的机构会做出调整。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-23 DOI: 10.1089/jwh.2024.0875
Mary S Hedges, Ebone Hill, Leila Tolaymat
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引用次数: 0
Institutional Culture of Belonging and Attrition Risk Among Women Health Care Professionals. 机构归属感文化与女性医疗保健专业人员的流失风险。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-23 DOI: 10.1089/jwh.2024.0321
Judith D Schaechter, Jacqueline R Starr, Julie K Silver

Objective: Attrition of women health care professionals is high, threatening patient care and advances in health care sciences. Women health care professionals have often reported experiencing challenges in the workplace that lower their sense of belonging and may precipitate their attrition. The current study sought to identify dimensions of workplace belonging in women health care professionals and to determine the relative strength of association of these belonging dimensions with intent to leave (ITL) their institution. Methods: Attendees of a continuing education course on women's leadership skills in health care were surveyed about their ITL and workplace belonging experiences. Dimensions of workplace belonging were identified by factor analysis. The strength of association between ITL and each workplace belonging dimension, as well as their relative strengths of association, were assessed in ordinal regression analyses. Results: Women comprised 99% of survey participants. Three dimensions of workplace belonging were identified: "institutional culture," "interactions with supervisor," and "interpersonal relationships." More frequent experiences of support in any of the three belonging dimensions associated strongly with lower ITL. When all three belonging dimensions were considered simultaneously, ITL remained strongly related with experiences of a supportive "institutional culture" (odds ratio 0.41, p < 0.0001), while it became much less strongly related with supportive experiences in the other two dimensions. Conclusions: These findings suggest a dominant role of institutional culture in attrition risk in women health care professionals. Interventions that foster an institutional culture of diversity, opportunities for career advancement, and inclusivity might be effective in improving retention of women health care professionals.

目的:女性医疗保健专业人员的流失率很高,威胁到病人护理和医疗保健科学的发展。女性医疗保健专业人员经常表示,在工作场所遇到的挑战降低了她们的归属感,并可能导致她们流失。本研究旨在确定女性医护专业人员的工作场所归属感维度,并确定这些归属感维度与离职意向(ITL)的相对关联强度。研究方法对参加关于女性在医疗保健领域的领导技能的继续教育课程的人员进行了关于其 ITL 和工作场所归属感经历的调查。通过因子分析确定了工作场所归属感的各个维度。在序数回归分析中评估了 ITL 与每个工作场所归属感维度之间的关联强度,以及它们之间的相对关联强度。结果显示99% 的调查参与者为女性。确定了工作场所归属感的三个维度:"机构文化"、"与主管的互动 "和 "人际关系"。在这三个归属感维度中的任何一个维度上获得更多支持的经历都与较低的 ITL 密切相关。当同时考虑所有三个归属感维度时,ITL 仍然与 "机构文化 "的支持性体验密切相关(几率比 0.41,p < 0.0001),而与其他两个维度的支持性体验的相关性则大大降低。结论这些研究结果表明,机构文化在女性医护人员的流失风险中起着主导作用。促进机构文化多样性、职业发展机会和包容性的干预措施可能会有效提高女性医护专业人员的留任率。
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引用次数: 0
Describing Adverse Pregnancy Events and Pregnancy-Associated Death Among Veterans. 描述退伍军人中的不良妊娠事件和与妊娠相关的死亡。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-20 DOI: 10.1089/jwh.2023.1046
Deirdre A Quinn, Florentina E Sileanu, Maria K Mor, Lisa S Callegari, Sonya Borrero

Background: Veterans who use VA pregnancy benefits may be at high risk for adverse pregnancy outcomes; however, little is known about rates of adverse pregnancy events or pregnancy-associated death among Veterans. Methods: We conducted a retrospective cohort study using VA national administrative data for Veterans ages 18-45 with at least one pregnancy outcome between October 2009 and September 2016 and a VA primary care visit within one year prior to pregnancy. We identified adverse events during pregnancy and up to 42 days after pregnancy and all-cause mortality within one year of pregnancy and compared prevalence of adverse events by Veteran race/ethnicity using adjusted logistic regression. Results: Pregnancies among Black Veterans had 69% higher odds of any adverse event than those among White Veterans (aOR = 1.69, 95% CI: 1.43, 2.00). All-cause mortality during pregnancy or within one year of pregnancy was recorded for 18 pregnancies, resulting in an estimated overall pregnancy-associated mortality rate of 76 deaths per 100,000 live births. Conclusions: We identified high overall rates of adverse pregnancy events and pregnancy-associated death among Veterans using VA benefits. As in non-VA populations, there were stark racial disparities in adverse pregnancy events among Veterans.

背景:使用退伍军人妊娠津贴的退伍军人可能是不良妊娠结局的高危人群;然而,人们对退伍军人中不良妊娠事件或妊娠相关死亡的发生率知之甚少。研究方法我们利用退伍军人事务部的国家管理数据开展了一项回顾性队列研究,研究对象为年龄在 18-45 岁之间、在 2009 年 10 月至 2016 年 9 月期间至少有一次妊娠结果、且在妊娠前一年内接受过退伍军人事务部初级保健就诊的退伍军人。我们确定了妊娠期间和妊娠后 42 天内的不良事件以及妊娠一年内的全因死亡率,并使用调整后的逻辑回归比较了不同退伍军人种族/族裔的不良事件发生率。结果显示黑人退伍军人怀孕后发生任何不良事件的几率比白人退伍军人高 69%(aOR = 1.69,95% CI:1.43, 2.00)。有 18 例妊娠记录了妊娠期间或妊娠后一年内的全因死亡率,估计每 10 万活产婴儿中与妊娠相关的总死亡率为 76 例。结论:我们发现,在使用退伍军人福利的退伍军人中,不良妊娠事件和妊娠相关死亡的总体发生率很高。与非退伍军人群体一样,退伍军人中的不良妊娠事件也存在明显的种族差异。
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引用次数: 0
Trends in Adverse Pregnancy Events Among Veterans: Racial Disparities and Care Coordination. 退伍军人妊娠不良事件的趋势:退伍军人中的不良妊娠事件趋势:种族差异和护理协调。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-20 DOI: 10.1089/jwh.2024.0690
Lynette Hamlin
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引用次数: 0
The Affordable Care Act Dependent Coverage Provision and Unintended Pregnancy. 平价医疗法案》受抚养人承保条款与意外怀孕。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-18 DOI: 10.1089/jwh.2023.0956
Colleen L MacCallum-Bridges,Robert Kaestner,Zhehui Luo,Claudia Holzman,Tim A Bruckner,Claire E Margerison
Background: Nearly half of all pregnancies in the United States are considered unintended (mistimed or unwanted), and this rate is even higher among younger and lower income women. The Affordable Care Act (ACA) dependent coverage provision may have influenced the frequency of unintended pregnancies by increasing accessibility to and affordability of family planning services among young adults. Furthermore, the impact of this provision may differ by young adult income level as those with lower income are less likely to be insured and thus more likely to benefit from this provision. Our objective was to estimate the association between the ACA dependent coverage provision and unintended pregnancy, overall, and by young adult income level. Methods: We applied a difference-in-differences approach to data from multiple cycles of the National Survey of Family Growth (n = 10,104) and compared trends in unintended pregnancy between those who were eligible to benefit (ages 18-25 years) and those who were ineligible to benefit (ages 26-33 years) from the provision, overall, and among income subgroups. Results: We found evidence that the dependent coverage provision was associated with a -7.4 percentage point reduction (95% CI: -13.5, -1.3) in the prevalence of unintended pregnancy among young adults with lower income (<100% of the federal poverty level). There was limited evidence, however, that the provision was associated with unintended pregnancy among young adults with higher income levels. Conclusions: These findings suggest the ACA dependent coverage provision may have reduced unintended pregnancy among a particularly high-risk group (i.e., young adults with lower income).
背景:在美国,近一半的怀孕被认为是意外怀孕(时机不当或不想要),而这一比例在年轻和低收入妇女中甚至更高。平价医疗法案》(ACA)中的 "受抚养人保险 "条款可能会通过提高计划生育服务在年轻人中的可及性和可负担性来影响意外怀孕的频率。此外,这一规定的影响可能因年轻成年人的收入水平而异,因为收入较低的人投保的可能性较小,因此更有可能从这一规定中受益。我们的目标是估算 ACA 受抚养人保险条款与意外怀孕之间的关系,包括总体关系和不同年轻成年人收入水平之间的关系。方法:我们对《全国家庭成长调查》多个周期的数据(n = 10,104 人)采用了差分法,比较了有资格从该条款中受益的人群(18-25 岁)和无资格受益的人群(26-33 岁)之间的意外怀孕趋势、总体情况以及不同收入亚群之间的趋势。结果:我们发现有证据表明,在收入较低(低于联邦贫困线的 100%)的年轻成年人中,受抚养人参保规定与意外怀孕率下降 -7.4 个百分点(95% CI:-13.5,-1.3)相关。然而,在收入水平较高的青壮年中,该规定与意外怀孕相关的证据有限。结论:这些研究结果表明,《联邦医疗保险法》的受抚养人保险规定可能减少了高危人群(即收入较低的年轻人)的意外怀孕。
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引用次数: 0
Risk Prediction Model for Child Sex Trafficking Among Female Child Welfare-Involved Youth: Welfare-Involved Female Sexual Exploitation Risk Assessment Tool. 涉及儿童福利的女性青少年中儿童性贩运的风险预测模型:涉及福利的女性性剥削风险评估工具》(Welfare-Involved Female Sexual Exploitation Risk Assessment Tool)。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-17 DOI: 10.1089/jwh.2024.0415
Jaya Prakash,Rishi Goel,Yi Mu,Bernard Rosner,Hanni Stoklosa
Background: Female child welfare-involved youths who are removed from the home are at risk of commercial sexual exploitation of children (CSEC). The aim of this study was to develop a prediction model to identify those at greatest risk of trafficking. Methods: Data were from the Florida Department of Children and Families' Florida Safe Families Network Database. A Cox proportional hazard regression of 60 cases and 3857 controls generated the proposed risk model. Results: Factors found to be associated with a higher risk of trafficking were quantified into point scores, generating the Welfare-Involved Female Sexual Exploitation Risk Assessment (WISER) tool with a cutoff of 20 points: first out-of-home placement at ≥15 years of age (11 points); run away from home in past year and age <15 years (40 points) or ≥15 years (16 points); English spoken as other language (14 points); on a psychotropic drug (17 points); congregate first placement (14 points); runaway/abducted status first "placement" (16 points); psychiatric facility experience (9 points); residential facility experience (7 points); and no time in temporary shelter (9 points). Of those who experienced CSEC, 92% had a WISER score above 20. Discussion: The WISER tool achieved good discrimination and calibration ability with a receiver operating characteristic for the validation data set of 0.923. The WISER tool can (1) inform risk assessment for CSEC among child welfare-involved females and (2) identify youths at greatest risk before they are harmed by trafficking.
背景:从家中带走的涉及儿童福利的女性青少年面临着对儿童进行商业性剥削(CSEC)的风险。本研究旨在开发一个预测模型,以识别那些面临最大贩运风险的青少年。研究方法数据来自佛罗里达州儿童和家庭部的佛罗里达州安全家庭网络数据库。通过对 60 例病例和 3857 例对照进行考克斯比例危险回归,建立了建议的风险模型。结果将发现的与较高人口贩运风险相关的因素量化为点数,生成了福利牵涉女性性剥削风险评估(WISER)工具,分界点为 20 点:首次家庭外安置年龄≥15 岁(11 分);过去一年离家出走且年龄小于 15 岁(40 分)或≥15 岁(16 分);英语为其他语言(14 分);服用精神药物(17 分);首次集中安置(14 分);离家出走/被绑架身份首次 "安置"(16 分);精神病院经历(9 分);寄宿机构经历(7 分);未在临时庇护所待过(9 分)。在经历过对儿童商业性剥削的人中,92%的人的 WISER 得分超过 20 分。讨论情况:WISER 工具具有良好的辨别和校准能力,验证数据集的接收器操作特征为 0.923。WISER 工具可以:(1)为涉及儿童福利的女性中的 CSEC 风险评估提供信息;(2)在贩运行为对青少年造成伤害之前识别出风险最大的青少年。
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引用次数: 0
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Journal of women's health
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