首页 > 最新文献

Journal of women's health最新文献

英文 中文
Institutional Culture of Belonging and Attrition Risk Among Women Health Care Professionals. 机构归属感文化与女性医疗保健专业人员的流失风险。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-23 DOI: 10.1089/jwh.2024.0321
Judith D Schaechter, Jacqueline R Starr, Julie K Silver

Objective: Attrition of women health care professionals is high, threatening patient care and advances in health care sciences. Women health care professionals have often reported experiencing challenges in the workplace that lower their sense of belonging and may precipitate their attrition. The current study sought to identify dimensions of workplace belonging in women health care professionals and to determine the relative strength of association of these belonging dimensions with intent to leave (ITL) their institution. Methods: Attendees of a continuing education course on women's leadership skills in health care were surveyed about their ITL and workplace belonging experiences. Dimensions of workplace belonging were identified by factor analysis. The strength of association between ITL and each workplace belonging dimension, as well as their relative strengths of association, were assessed in ordinal regression analyses. Results: Women comprised 99% of survey participants. Three dimensions of workplace belonging were identified: "institutional culture," "interactions with supervisor," and "interpersonal relationships." More frequent experiences of support in any of the three belonging dimensions associated strongly with lower ITL. When all three belonging dimensions were considered simultaneously, ITL remained strongly related with experiences of a supportive "institutional culture" (odds ratio 0.41, p < 0.0001), while it became much less strongly related with supportive experiences in the other two dimensions. Conclusions: These findings suggest a dominant role of institutional culture in attrition risk in women health care professionals. Interventions that foster an institutional culture of diversity, opportunities for career advancement, and inclusivity might be effective in improving retention of women health care professionals.

目的:女性医疗保健专业人员的流失率很高,威胁到病人护理和医疗保健科学的发展。女性医疗保健专业人员经常表示,在工作场所遇到的挑战降低了她们的归属感,并可能导致她们流失。本研究旨在确定女性医护专业人员的工作场所归属感维度,并确定这些归属感维度与离职意向(ITL)的相对关联强度。研究方法对参加关于女性在医疗保健领域的领导技能的继续教育课程的人员进行了关于其 ITL 和工作场所归属感经历的调查。通过因子分析确定了工作场所归属感的各个维度。在序数回归分析中评估了 ITL 与每个工作场所归属感维度之间的关联强度,以及它们之间的相对关联强度。结果显示99% 的调查参与者为女性。确定了工作场所归属感的三个维度:"机构文化"、"与主管的互动 "和 "人际关系"。在这三个归属感维度中的任何一个维度上获得更多支持的经历都与较低的 ITL 密切相关。当同时考虑所有三个归属感维度时,ITL 仍然与 "机构文化 "的支持性体验密切相关(几率比 0.41,p < 0.0001),而与其他两个维度的支持性体验的相关性则大大降低。结论这些研究结果表明,机构文化在女性医护人员的流失风险中起着主导作用。促进机构文化多样性、职业发展机会和包容性的干预措施可能会有效提高女性医护专业人员的留任率。
{"title":"Institutional Culture of Belonging and Attrition Risk Among Women Health Care Professionals.","authors":"Judith D Schaechter, Jacqueline R Starr, Julie K Silver","doi":"10.1089/jwh.2024.0321","DOIUrl":"https://doi.org/10.1089/jwh.2024.0321","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Attrition of women health care professionals is high, threatening patient care and advances in health care sciences. Women health care professionals have often reported experiencing challenges in the workplace that lower their sense of belonging and may precipitate their attrition. The current study sought to identify dimensions of workplace belonging in women health care professionals and to determine the relative strength of association of these belonging dimensions with intent to leave (ITL) their institution. <b><i>Methods:</i></b> Attendees of a continuing education course on women's leadership skills in health care were surveyed about their ITL and workplace belonging experiences. Dimensions of workplace belonging were identified by factor analysis. The strength of association between ITL and each workplace belonging dimension, as well as their relative strengths of association, were assessed in ordinal regression analyses. <b><i>Results:</i></b> Women comprised 99% of survey participants. Three dimensions of workplace belonging were identified: \"institutional culture,\" \"interactions with supervisor,\" and \"interpersonal relationships.\" More frequent experiences of support in any of the three belonging dimensions associated strongly with lower ITL. When all three belonging dimensions were considered simultaneously, ITL remained strongly related with experiences of a supportive \"institutional culture\" (odds ratio 0.41, <i>p</i> < 0.0001), while it became much less strongly related with supportive experiences in the other two dimensions. <b><i>Conclusions:</i></b> These findings suggest a dominant role of institutional culture in attrition risk in women health care professionals. Interventions that foster an institutional culture of diversity, opportunities for career advancement, and inclusivity might be effective in improving retention of women health care professionals.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Describing Adverse Pregnancy Events and Pregnancy-Associated Death Among Veterans. 描述退伍军人中的不良妊娠事件和与妊娠相关的死亡。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-20 DOI: 10.1089/jwh.2023.1046
Deirdre A Quinn, Florentina E Sileanu, Maria K Mor, Lisa S Callegari, Sonya Borrero

Background: Veterans who use VA pregnancy benefits may be at high risk for adverse pregnancy outcomes; however, little is known about rates of adverse pregnancy events or pregnancy-associated death among Veterans. Methods: We conducted a retrospective cohort study using VA national administrative data for Veterans ages 18-45 with at least one pregnancy outcome between October 2009 and September 2016 and a VA primary care visit within one year prior to pregnancy. We identified adverse events during pregnancy and up to 42 days after pregnancy and all-cause mortality within one year of pregnancy and compared prevalence of adverse events by Veteran race/ethnicity using adjusted logistic regression. Results: Pregnancies among Black Veterans had 69% higher odds of any adverse event than those among White Veterans (aOR = 1.69, 95% CI: 1.43, 2.00). All-cause mortality during pregnancy or within one year of pregnancy was recorded for 18 pregnancies, resulting in an estimated overall pregnancy-associated mortality rate of 76 deaths per 100,000 live births. Conclusions: We identified high overall rates of adverse pregnancy events and pregnancy-associated death among Veterans using VA benefits. As in non-VA populations, there were stark racial disparities in adverse pregnancy events among Veterans.

背景:使用退伍军人妊娠津贴的退伍军人可能是不良妊娠结局的高危人群;然而,人们对退伍军人中不良妊娠事件或妊娠相关死亡的发生率知之甚少。研究方法我们利用退伍军人事务部的国家管理数据开展了一项回顾性队列研究,研究对象为年龄在 18-45 岁之间、在 2009 年 10 月至 2016 年 9 月期间至少有一次妊娠结果、且在妊娠前一年内接受过退伍军人事务部初级保健就诊的退伍军人。我们确定了妊娠期间和妊娠后 42 天内的不良事件以及妊娠一年内的全因死亡率,并使用调整后的逻辑回归比较了不同退伍军人种族/族裔的不良事件发生率。结果显示黑人退伍军人怀孕后发生任何不良事件的几率比白人退伍军人高 69%(aOR = 1.69,95% CI:1.43, 2.00)。有 18 例妊娠记录了妊娠期间或妊娠后一年内的全因死亡率,估计每 10 万活产婴儿中与妊娠相关的总死亡率为 76 例。结论:我们发现,在使用退伍军人福利的退伍军人中,不良妊娠事件和妊娠相关死亡的总体发生率很高。与非退伍军人群体一样,退伍军人中的不良妊娠事件也存在明显的种族差异。
{"title":"Describing Adverse Pregnancy Events and Pregnancy-Associated Death Among Veterans.","authors":"Deirdre A Quinn, Florentina E Sileanu, Maria K Mor, Lisa S Callegari, Sonya Borrero","doi":"10.1089/jwh.2023.1046","DOIUrl":"https://doi.org/10.1089/jwh.2023.1046","url":null,"abstract":"<p><p><b><i>Background:</i></b> Veterans who use VA pregnancy benefits may be at high risk for adverse pregnancy outcomes; however, little is known about rates of adverse pregnancy events or pregnancy-associated death among Veterans. <b><i>Methods:</i></b> We conducted a retrospective cohort study using VA national administrative data for Veterans ages 18-45 with at least one pregnancy outcome between October 2009 and September 2016 and a VA primary care visit within one year prior to pregnancy. We identified adverse events during pregnancy and up to 42 days after pregnancy and all-cause mortality within one year of pregnancy and compared prevalence of adverse events by Veteran race/ethnicity using adjusted logistic regression. <b><i>Results:</i></b> Pregnancies among Black Veterans had 69% higher odds of any adverse event than those among White Veterans (aOR = 1.69, 95% CI: 1.43, 2.00). All-cause mortality during pregnancy or within one year of pregnancy was recorded for 18 pregnancies, resulting in an estimated overall pregnancy-associated mortality rate of 76 deaths per 100,000 live births. <b><i>Conclusions:</i></b> We identified high overall rates of adverse pregnancy events and pregnancy-associated death among Veterans using VA benefits. As in non-VA populations, there were stark racial disparities in adverse pregnancy events among Veterans.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Adverse Pregnancy Events Among Veterans: Racial Disparities and Care Coordination. 退伍军人妊娠不良事件的趋势:退伍军人中的不良妊娠事件趋势:种族差异和护理协调。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-20 DOI: 10.1089/jwh.2024.0690
Lynette Hamlin
{"title":"Trends in Adverse Pregnancy Events Among Veterans: Racial Disparities and Care Coordination.","authors":"Lynette Hamlin","doi":"10.1089/jwh.2024.0690","DOIUrl":"https://doi.org/10.1089/jwh.2024.0690","url":null,"abstract":"","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142290208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Affordable Care Act Dependent Coverage Provision and Unintended Pregnancy. 平价医疗法案》受抚养人承保条款与意外怀孕。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-18 DOI: 10.1089/jwh.2023.0956
Colleen L MacCallum-Bridges,Robert Kaestner,Zhehui Luo,Claudia Holzman,Tim A Bruckner,Claire E Margerison
Background: Nearly half of all pregnancies in the United States are considered unintended (mistimed or unwanted), and this rate is even higher among younger and lower income women. The Affordable Care Act (ACA) dependent coverage provision may have influenced the frequency of unintended pregnancies by increasing accessibility to and affordability of family planning services among young adults. Furthermore, the impact of this provision may differ by young adult income level as those with lower income are less likely to be insured and thus more likely to benefit from this provision. Our objective was to estimate the association between the ACA dependent coverage provision and unintended pregnancy, overall, and by young adult income level. Methods: We applied a difference-in-differences approach to data from multiple cycles of the National Survey of Family Growth (n = 10,104) and compared trends in unintended pregnancy between those who were eligible to benefit (ages 18-25 years) and those who were ineligible to benefit (ages 26-33 years) from the provision, overall, and among income subgroups. Results: We found evidence that the dependent coverage provision was associated with a -7.4 percentage point reduction (95% CI: -13.5, -1.3) in the prevalence of unintended pregnancy among young adults with lower income (<100% of the federal poverty level). There was limited evidence, however, that the provision was associated with unintended pregnancy among young adults with higher income levels. Conclusions: These findings suggest the ACA dependent coverage provision may have reduced unintended pregnancy among a particularly high-risk group (i.e., young adults with lower income).
背景:在美国,近一半的怀孕被认为是意外怀孕(时机不当或不想要),而这一比例在年轻和低收入妇女中甚至更高。平价医疗法案》(ACA)中的 "受抚养人保险 "条款可能会通过提高计划生育服务在年轻人中的可及性和可负担性来影响意外怀孕的频率。此外,这一规定的影响可能因年轻成年人的收入水平而异,因为收入较低的人投保的可能性较小,因此更有可能从这一规定中受益。我们的目标是估算 ACA 受抚养人保险条款与意外怀孕之间的关系,包括总体关系和不同年轻成年人收入水平之间的关系。方法:我们对《全国家庭成长调查》多个周期的数据(n = 10,104 人)采用了差分法,比较了有资格从该条款中受益的人群(18-25 岁)和无资格受益的人群(26-33 岁)之间的意外怀孕趋势、总体情况以及不同收入亚群之间的趋势。结果:我们发现有证据表明,在收入较低(低于联邦贫困线的 100%)的年轻成年人中,受抚养人参保规定与意外怀孕率下降 -7.4 个百分点(95% CI:-13.5,-1.3)相关。然而,在收入水平较高的青壮年中,该规定与意外怀孕相关的证据有限。结论:这些研究结果表明,《联邦医疗保险法》的受抚养人保险规定可能减少了高危人群(即收入较低的年轻人)的意外怀孕。
{"title":"The Affordable Care Act Dependent Coverage Provision and Unintended Pregnancy.","authors":"Colleen L MacCallum-Bridges,Robert Kaestner,Zhehui Luo,Claudia Holzman,Tim A Bruckner,Claire E Margerison","doi":"10.1089/jwh.2023.0956","DOIUrl":"https://doi.org/10.1089/jwh.2023.0956","url":null,"abstract":"Background: Nearly half of all pregnancies in the United States are considered unintended (mistimed or unwanted), and this rate is even higher among younger and lower income women. The Affordable Care Act (ACA) dependent coverage provision may have influenced the frequency of unintended pregnancies by increasing accessibility to and affordability of family planning services among young adults. Furthermore, the impact of this provision may differ by young adult income level as those with lower income are less likely to be insured and thus more likely to benefit from this provision. Our objective was to estimate the association between the ACA dependent coverage provision and unintended pregnancy, overall, and by young adult income level. Methods: We applied a difference-in-differences approach to data from multiple cycles of the National Survey of Family Growth (n = 10,104) and compared trends in unintended pregnancy between those who were eligible to benefit (ages 18-25 years) and those who were ineligible to benefit (ages 26-33 years) from the provision, overall, and among income subgroups. Results: We found evidence that the dependent coverage provision was associated with a -7.4 percentage point reduction (95% CI: -13.5, -1.3) in the prevalence of unintended pregnancy among young adults with lower income (<100% of the federal poverty level). There was limited evidence, however, that the provision was associated with unintended pregnancy among young adults with higher income levels. Conclusions: These findings suggest the ACA dependent coverage provision may have reduced unintended pregnancy among a particularly high-risk group (i.e., young adults with lower income).","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":"14 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Prediction Model for Child Sex Trafficking Among Female Child Welfare-Involved Youth: Welfare-Involved Female Sexual Exploitation Risk Assessment Tool. 涉及儿童福利的女性青少年中儿童性贩运的风险预测模型:涉及福利的女性性剥削风险评估工具》(Welfare-Involved Female Sexual Exploitation Risk Assessment Tool)。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-17 DOI: 10.1089/jwh.2024.0415
Jaya Prakash,Rishi Goel,Yi Mu,Bernard Rosner,Hanni Stoklosa
Background: Female child welfare-involved youths who are removed from the home are at risk of commercial sexual exploitation of children (CSEC). The aim of this study was to develop a prediction model to identify those at greatest risk of trafficking. Methods: Data were from the Florida Department of Children and Families' Florida Safe Families Network Database. A Cox proportional hazard regression of 60 cases and 3857 controls generated the proposed risk model. Results: Factors found to be associated with a higher risk of trafficking were quantified into point scores, generating the Welfare-Involved Female Sexual Exploitation Risk Assessment (WISER) tool with a cutoff of 20 points: first out-of-home placement at ≥15 years of age (11 points); run away from home in past year and age <15 years (40 points) or ≥15 years (16 points); English spoken as other language (14 points); on a psychotropic drug (17 points); congregate first placement (14 points); runaway/abducted status first "placement" (16 points); psychiatric facility experience (9 points); residential facility experience (7 points); and no time in temporary shelter (9 points). Of those who experienced CSEC, 92% had a WISER score above 20. Discussion: The WISER tool achieved good discrimination and calibration ability with a receiver operating characteristic for the validation data set of 0.923. The WISER tool can (1) inform risk assessment for CSEC among child welfare-involved females and (2) identify youths at greatest risk before they are harmed by trafficking.
背景:从家中带走的涉及儿童福利的女性青少年面临着对儿童进行商业性剥削(CSEC)的风险。本研究旨在开发一个预测模型,以识别那些面临最大贩运风险的青少年。研究方法数据来自佛罗里达州儿童和家庭部的佛罗里达州安全家庭网络数据库。通过对 60 例病例和 3857 例对照进行考克斯比例危险回归,建立了建议的风险模型。结果将发现的与较高人口贩运风险相关的因素量化为点数,生成了福利牵涉女性性剥削风险评估(WISER)工具,分界点为 20 点:首次家庭外安置年龄≥15 岁(11 分);过去一年离家出走且年龄小于 15 岁(40 分)或≥15 岁(16 分);英语为其他语言(14 分);服用精神药物(17 分);首次集中安置(14 分);离家出走/被绑架身份首次 "安置"(16 分);精神病院经历(9 分);寄宿机构经历(7 分);未在临时庇护所待过(9 分)。在经历过对儿童商业性剥削的人中,92%的人的 WISER 得分超过 20 分。讨论情况:WISER 工具具有良好的辨别和校准能力,验证数据集的接收器操作特征为 0.923。WISER 工具可以:(1)为涉及儿童福利的女性中的 CSEC 风险评估提供信息;(2)在贩运行为对青少年造成伤害之前识别出风险最大的青少年。
{"title":"Risk Prediction Model for Child Sex Trafficking Among Female Child Welfare-Involved Youth: Welfare-Involved Female Sexual Exploitation Risk Assessment Tool.","authors":"Jaya Prakash,Rishi Goel,Yi Mu,Bernard Rosner,Hanni Stoklosa","doi":"10.1089/jwh.2024.0415","DOIUrl":"https://doi.org/10.1089/jwh.2024.0415","url":null,"abstract":"Background: Female child welfare-involved youths who are removed from the home are at risk of commercial sexual exploitation of children (CSEC). The aim of this study was to develop a prediction model to identify those at greatest risk of trafficking. Methods: Data were from the Florida Department of Children and Families' Florida Safe Families Network Database. A Cox proportional hazard regression of 60 cases and 3857 controls generated the proposed risk model. Results: Factors found to be associated with a higher risk of trafficking were quantified into point scores, generating the Welfare-Involved Female Sexual Exploitation Risk Assessment (WISER) tool with a cutoff of 20 points: first out-of-home placement at ≥15 years of age (11 points); run away from home in past year and age <15 years (40 points) or ≥15 years (16 points); English spoken as other language (14 points); on a psychotropic drug (17 points); congregate first placement (14 points); runaway/abducted status first \"placement\" (16 points); psychiatric facility experience (9 points); residential facility experience (7 points); and no time in temporary shelter (9 points). Of those who experienced CSEC, 92% had a WISER score above 20. Discussion: The WISER tool achieved good discrimination and calibration ability with a receiver operating characteristic for the validation data set of 0.923. The WISER tool can (1) inform risk assessment for CSEC among child welfare-involved females and (2) identify youths at greatest risk before they are harmed by trafficking.","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":"46 29 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142248133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Primary Human Papillomavirus Screening: Women's Perceptions of New Cervical Cancer Screening Recommendations. 人类乳头瘤病毒初级筛查:妇女对宫颈癌筛查新建议的看法。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-11 DOI: 10.1089/jwh.2023.1180
Nancy T Cannizzaro,Brian S Mittman,Erin E Hahn,Quyen Ngo-Metzger,Michael K Gould,Chunyi Hsu,Ernest Shen,Devansu Tewari,Chun R Chao
Background: Current clinical guidelines recommended primary human papillomavirus (HPV) screening for cervical cancer testing. Previous studies reported patient-level barriers (e.g., limited knowledge and attachment to Pap test) that may hinder wide adoption of primary HPV screening. We assessed these women-level factors following the implementation of primary HPV screening (July 2020) at Kaiser Permanente Southern California (KPSC). Methods: We administered a patient survey (mail and on-line) to female KPSC members aged 30-65 years who received primary HPV screening between October and December 2020. Those who preferred English vs. Spanish language were sampled separately. The survey included domains on knowledge about HPV and HPV screening, awareness of screening guidelines, and attitudes about HPV testing. Demographic data were collected using electronic health records. We used weighted multivariable logistic and modified Poisson regressions for associations between language preference and survey responses. Results: In total, 3,009 surveys were returned (38.0% response rate). Few women (7.0%) found HPV testing as an acceptable screening method. The majority of women (92.2%) remained unaware that HPV testing can replace Pap test for screening. The Pap test was the most preferred screening approach for 33.2% Spanish-speaking women vs. 19.9% English-speaking women. Only 20.6% knew that women aged 30-65 years can be screened every 5 years with cotest or primary HPV screening. Most women (96.4%) did not perceive stigma about taking the HPV test. Conclusion: Proactive patient education will help improve women's knowledge about primary HPV screening, which may facilitate its implementation in additional health care settings.
背景:目前的临床指南推荐在宫颈癌检测中进行人类乳头瘤病毒(HPV)初筛。先前的研究报告了患者层面的障碍(如对巴氏试验的有限了解和依恋),这些障碍可能会阻碍 HPV 初筛的广泛采用。我们在南加州凯撒医疗集团(KPSC)实施 HPV 初筛(2020 年 7 月)后对这些妇女层面的因素进行了评估。方法:我们对 2020 年 10 月至 12 月期间接受 HPV 初筛的 30-65 岁 KPSC 女性会员进行了患者调查(邮寄和在线)。对选择英语和西班牙语的患者分别进行了抽样调查。调查内容包括对 HPV 和 HPV 筛查的了解、对筛查指南的认识以及对 HPV 检测的态度。人口统计学数据通过电子健康记录收集。我们使用加权多变量逻辑回归和修正泊松回归分析了语言偏好与调查回答之间的关联。结果:共收回 3,009 份调查问卷(回复率为 38.0%)。很少有妇女(7.0%)认为 HPV 检测是一种可接受的筛查方法。大多数妇女(92.2%)仍不知道人乳头瘤病毒检测可以取代巴氏试验进行筛查。33.2%的讲西班牙语的妇女(19.9%的讲英语的妇女)最喜欢的筛查方法是子宫颈抹片检查。只有 20.6% 的人知道 30-65 岁的妇女可以每 5 年进行一次联检或 HPV 初筛。大多数妇女(96.4%)不认为接受 HPV 检测是一种耻辱。结论积极主动的患者教育将有助于提高妇女对 HPV 初筛的认识,从而促进其在更多医疗机构的实施。
{"title":"Primary Human Papillomavirus Screening: Women's Perceptions of New Cervical Cancer Screening Recommendations.","authors":"Nancy T Cannizzaro,Brian S Mittman,Erin E Hahn,Quyen Ngo-Metzger,Michael K Gould,Chunyi Hsu,Ernest Shen,Devansu Tewari,Chun R Chao","doi":"10.1089/jwh.2023.1180","DOIUrl":"https://doi.org/10.1089/jwh.2023.1180","url":null,"abstract":"Background: Current clinical guidelines recommended primary human papillomavirus (HPV) screening for cervical cancer testing. Previous studies reported patient-level barriers (e.g., limited knowledge and attachment to Pap test) that may hinder wide adoption of primary HPV screening. We assessed these women-level factors following the implementation of primary HPV screening (July 2020) at Kaiser Permanente Southern California (KPSC). Methods: We administered a patient survey (mail and on-line) to female KPSC members aged 30-65 years who received primary HPV screening between October and December 2020. Those who preferred English vs. Spanish language were sampled separately. The survey included domains on knowledge about HPV and HPV screening, awareness of screening guidelines, and attitudes about HPV testing. Demographic data were collected using electronic health records. We used weighted multivariable logistic and modified Poisson regressions for associations between language preference and survey responses. Results: In total, 3,009 surveys were returned (38.0% response rate). Few women (7.0%) found HPV testing as an acceptable screening method. The majority of women (92.2%) remained unaware that HPV testing can replace Pap test for screening. The Pap test was the most preferred screening approach for 33.2% Spanish-speaking women vs. 19.9% English-speaking women. Only 20.6% knew that women aged 30-65 years can be screened every 5 years with cotest or primary HPV screening. Most women (96.4%) did not perceive stigma about taking the HPV test. Conclusion: Proactive patient education will help improve women's knowledge about primary HPV screening, which may facilitate its implementation in additional health care settings.","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":"1 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142181712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Qualitative Exploration of the "Guilt Gap" Among Physician-Faculty with Caregiving Responsibilities. 对有照顾责任的医生-教师之间 "内疚差距 "的定性探索。
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-11 DOI: 10.1089/jwh.2024.0106
Jamie Takayesu,Lauren Szczygiel,Rochelle D Jones,Lydia Perry,Laura Balcer,Gail Daumit,Wonder Drake,Heather Gatcombe,Christina Mangurian,Bess Marshall,Judith Regensteiner,Reshma Jagsi
Introduction: Differences in time commitments and resources contribute to the difficulties of work-life integration for many physician-scientists, particularly for women with family caregiving responsibilities. Understanding the challenges faced by this population is critical for the retention of these critical members of the workforce. Methods: We conducted semi-structured telephone interviews with recipients of the 2017 Doris Duke Charitable Foundation's Fund to Retain Clinical Scientists (FRCS) and reviewed application narratives from the 2020 award recipients. Award recipients were asked about their caregiving responsibilities and careers, particularly as they related to the impact of the FRCS award and the aftereffects of the COVID-19 pandemic. Analysts then iteratively revised the coding scheme and interpreted the data using qualitative thematic analysis. Results: Of the 14 interviewees and 19 narrative contributors, 25 (76%) were women. The main qualitative themes that emerged were as follows: (1) women experience unrealistically high caregiving burdens, (2) women are overburdened by disadvantageous and undervalued expectations at work, (3) work-life expectations increased during the COVID-19 pandemic, and (4) unrealistic work-life expectations led to guilt and burnout. Conclusions: These findings provide a rich understanding of the factors contributing to guilt and burnout among physician-scientists, particularly women, and how work duties that increase physician obligations exacerbated these challenges. Understanding these experiences is critical to supporting and retaining a diverse workforce in academic medicine.
导言:时间承诺和资源方面的差异造成了许多医生科学家在工作与生活融合方面的困难,尤其是对于需要照顾家庭的女性而言。了解这部分人群所面临的挑战对于留住这些重要的人才至关重要。方法:我们对 2017 年多丽丝-杜克慈善基金会 "留住临床科学家基金"(FRCS)的获奖者进行了半结构化电话访谈,并审查了 2020 年获奖者的申请陈述。获奖者被问及他们的护理责任和职业生涯,特别是与 FRCS 奖项的影响和 COVID-19 大流行的后遗症有关的情况。分析人员随后反复修订了编码方案,并使用定性专题分析法对数据进行了解释。结果:在 14 位受访者和 19 位叙述者中,25 位(76%)为女性。出现的主要定性主题如下:(1) 女性承受着不切实际的高护理负担,(2) 女性在工作中被不利和低估的期望压得喘不过气来,(3) 在 COVID-19 大流行期间,对工作和生活的期望有所提高,(4) 不切实际的工作和生活期望导致内疚和职业倦怠。结论:这些发现提供了一个丰富的视角,让我们了解导致医生科学家(尤其是女性)内疚和职业倦怠的因素,以及增加医生义务的工作职责是如何加剧这些挑战的。了解这些经历对于支持和留住学术医学领域的多元化人才至关重要。
{"title":"Qualitative Exploration of the \"Guilt Gap\" Among Physician-Faculty with Caregiving Responsibilities.","authors":"Jamie Takayesu,Lauren Szczygiel,Rochelle D Jones,Lydia Perry,Laura Balcer,Gail Daumit,Wonder Drake,Heather Gatcombe,Christina Mangurian,Bess Marshall,Judith Regensteiner,Reshma Jagsi","doi":"10.1089/jwh.2024.0106","DOIUrl":"https://doi.org/10.1089/jwh.2024.0106","url":null,"abstract":"Introduction: Differences in time commitments and resources contribute to the difficulties of work-life integration for many physician-scientists, particularly for women with family caregiving responsibilities. Understanding the challenges faced by this population is critical for the retention of these critical members of the workforce. Methods: We conducted semi-structured telephone interviews with recipients of the 2017 Doris Duke Charitable Foundation's Fund to Retain Clinical Scientists (FRCS) and reviewed application narratives from the 2020 award recipients. Award recipients were asked about their caregiving responsibilities and careers, particularly as they related to the impact of the FRCS award and the aftereffects of the COVID-19 pandemic. Analysts then iteratively revised the coding scheme and interpreted the data using qualitative thematic analysis. Results: Of the 14 interviewees and 19 narrative contributors, 25 (76%) were women. The main qualitative themes that emerged were as follows: (1) women experience unrealistically high caregiving burdens, (2) women are overburdened by disadvantageous and undervalued expectations at work, (3) work-life expectations increased during the COVID-19 pandemic, and (4) unrealistic work-life expectations led to guilt and burnout. Conclusions: These findings provide a rich understanding of the factors contributing to guilt and burnout among physician-scientists, particularly women, and how work duties that increase physician obligations exacerbated these challenges. Understanding these experiences is critical to supporting and retaining a diverse workforce in academic medicine.","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":"117 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142181710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Frequently Is Ultrasound Required to Diagnose Polycystic Ovary Syndrome in a Clinical Population? 在临床人群中,超声波诊断多囊卵巢综合征的频率是多少?
IF 3.5 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-10 DOI: 10.1089/jwh.2024.0186
Lauren Pace,Joshua Waldeck,Jessica Chan,Margareta Pisarska,Ricardo Azziz
Background: Polycystic ovary syndrome (PCOS) is a common endocrine condition, affecting up to 20% of reproductive aged women worldwide. Polycystic ovarian morphology (PCOM) may be present, but is not required for diagnosis. Our study seeks to evaluate the utility of ultrasound in diagnosing or excluding PCOS by 2023 International Guidelines Criteria. Materials and Methods: Subjects were patients seen in a tertiary care referral clinic in whom other causes of hyperandrogenism (HA) were ruled out. All underwent complete history, physical, modified Ferriman Gallwey scoring, and serum androgen testing; followed by transvaginal ultrasound (TVUS) to assess ovarian morphology if indicated. PCOM was identified as antral follicle count ≥20 and/or ovarian volume >10 mL in at least one ovary. After clinical classification, PCOS was diagnosed by at least two of three: biochemical/clinical HA, ovulatory dysfunction (OD), and PCOM. Statistics were calculated using Fisher's exact test and chi-square. Results: In total, 454 subjects were included. 299 were classified as group A/B and did not require TVUS for diagnosis. Of 82 subjects with HA alone, 50 (61.0%) were classified as group C after demonstrating PCOM. Fifty-five subjects had OD alone, 37 (67.3%) of which were classified as group D based on PCOM. In total, 137/454, or 30.2% of subjects required TVUS for diagnosis or exclusion of PCOS. Conclusions: TVUS was necessary in less than one-third of subjects, primarily identifying PCOS groups C or D. Selective use of ovarian ultrasonography may reduce the costs and complexity of epidemiological and clinical studies for PCOS.
背景:多囊卵巢综合征(PCOS多囊卵巢综合征(PCOS)是一种常见的内分泌疾病,影响着全球多达 20% 的育龄妇女。多囊卵巢形态(PCOM)可能存在,但并非诊断的必要条件。我们的研究旨在评估超声波在根据 2023 年国际指南标准诊断或排除多囊卵巢综合症方面的效用。材料与方法:受试者是在一家三级医疗转诊诊所就诊并排除了其他高雄激素症(HA)病因的患者。所有受试者均接受了完整的病史、体格检查、改良费里曼-盖尔韦评分和血清雄激素检测;如果有必要,还接受了经阴道超声检查(TVUS)以评估卵巢形态。至少一个卵巢的前卵泡数≥20和/或卵巢体积>10 mL即为多囊卵巢综合征。临床分类后,多囊卵巢综合症的诊断标准为生化/临床 HA、排卵功能障碍 (OD) 和 PCOM 三项中的至少两项。统计采用费雪精确检验和卡方检验。结果共纳入 454 名受试者。其中 299 例被归为 A/B 组,无需 TVUS 诊断。在 82 例仅有 HA 的受试者中,50 例(61.0%)在显示出 PCOM 后被归为 C 组。55 例受试者仅有 OD,其中 37 例(67.3%)根据 PCOM 被归为 D 组。总共有 137/454 例受试者(占 30.2%)需要通过 TVUS 诊断或排除多囊卵巢综合症。结论:选择性使用卵巢超声波检查可降低多囊卵巢综合症流行病学和临床研究的成本和复杂性。
{"title":"How Frequently Is Ultrasound Required to Diagnose Polycystic Ovary Syndrome in a Clinical Population?","authors":"Lauren Pace,Joshua Waldeck,Jessica Chan,Margareta Pisarska,Ricardo Azziz","doi":"10.1089/jwh.2024.0186","DOIUrl":"https://doi.org/10.1089/jwh.2024.0186","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) is a common endocrine condition, affecting up to 20% of reproductive aged women worldwide. Polycystic ovarian morphology (PCOM) may be present, but is not required for diagnosis. Our study seeks to evaluate the utility of ultrasound in diagnosing or excluding PCOS by 2023 International Guidelines Criteria. Materials and Methods: Subjects were patients seen in a tertiary care referral clinic in whom other causes of hyperandrogenism (HA) were ruled out. All underwent complete history, physical, modified Ferriman Gallwey scoring, and serum androgen testing; followed by transvaginal ultrasound (TVUS) to assess ovarian morphology if indicated. PCOM was identified as antral follicle count ≥20 and/or ovarian volume >10 mL in at least one ovary. After clinical classification, PCOS was diagnosed by at least two of three: biochemical/clinical HA, ovulatory dysfunction (OD), and PCOM. Statistics were calculated using Fisher's exact test and chi-square. Results: In total, 454 subjects were included. 299 were classified as group A/B and did not require TVUS for diagnosis. Of 82 subjects with HA alone, 50 (61.0%) were classified as group C after demonstrating PCOM. Fifty-five subjects had OD alone, 37 (67.3%) of which were classified as group D based on PCOM. In total, 137/454, or 30.2% of subjects required TVUS for diagnosis or exclusion of PCOS. Conclusions: TVUS was necessary in less than one-third of subjects, primarily identifying PCOS groups C or D. Selective use of ovarian ultrasonography may reduce the costs and complexity of epidemiological and clinical studies for PCOS.","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":"55 1","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142181711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of Human Papillomavirus Vaccination in the Postpartum Period for Individuals Aged 18-26. 18-26 岁人群产后接种人类乳头瘤病毒疫苗的预测因素。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-06 DOI: 10.1089/jwh.2024.0551
Christine G T Nguyen, Ava Mandelbaum, Lucy Ward, Katherine Bolten, Keenan Yanit, Jessica Currier, Amanda S Bruegl

Background: Human papillomavirus (HPV) vaccination during the postpartum period is an opportunity for vaccine eligible individuals to be vaccinated. Objective: Identify predictors of vaccine acceptance in the postpartum period among patients aged 18-26. Study Design: A retrospective chart review was conducted to evaluate the rate of HPV vaccination to eligible postpartum patients aged 18-26 who delivered between January 2021 and May 2023 at our institution. Clinical and demographic data were extracted. Comparisons were made between fully vaccinated individuals and those who were unvaccinated or incompletely vaccinated. Variables significantly associated with vaccination status or acceptance were included in a multivariable logistic regression model. Results: Of the 1,130 patients who met the study inclusion criteria, 42.1% were eligible for postpartum HPV vaccination. The average age was 23 years, the majority White (74.5%), and English speaking (93.1%). Nineteen percent of eligible patients accepted HPV vaccination, with differences between those who accepted or declined the vaccine identified in: preferred language, tobacco use, delivering provider's specialty, and receiving any vaccination during pregnancy. Spanish-speaking patients had >5× the odds of accepting the vaccine compared with English-speaking patients. Smokers, patients delivered by a family medicine provider, and those who accepted any vaccine during pregnancy had more than twice the odds of receiving the vaccine postpartum. Conclusion(s): The postpartum period remains an opportunity to provide HPV vaccination. Our study identified patients less likely to be vaccinated prior to delivery, as well as patients who are more likely to accept vaccinations postpartum.

背景:产后期间接种人乳头瘤病毒 (HPV) 疫苗是符合疫苗接种条件者接种疫苗的一个机会。目标:确定产后妇女接受疫苗接种的预测因素:确定 18-26 岁患者在产后接受疫苗接种的预测因素。研究设计:对本机构 2021 年 1 月至 2023 年 5 月间分娩的 18-26 岁合格产后患者的 HPV 疫苗接种率进行回顾性病历审查。我们提取了临床和人口统计学数据。对完全接种者和未接种者或未完全接种者进行了比较。在多变量逻辑回归模型中纳入了与疫苗接种状况或接受度明显相关的变量。结果在符合研究纳入标准的 1130 名患者中,42.1% 符合产后接种 HPV 疫苗的条件。平均年龄为 23 岁,大多数为白人(74.5%),讲英语(93.1%)。符合条件的患者中有 19% 接受了 HPV 疫苗接种,接受或拒绝接受疫苗接种的患者在以下方面存在差异:首选语言、吸烟情况、接生医生的专业以及是否在孕期接受过任何疫苗接种。与讲英语的患者相比,讲西班牙语的患者接受疫苗接种的几率是讲英语患者的 5 倍。吸烟者、由家庭医生接生的患者以及在孕期接受过任何疫苗接种的患者在产后接种疫苗的几率是前者的两倍多。结论产后仍是接种 HPV 疫苗的好时机。我们的研究发现了产前不太可能接种疫苗的患者,以及产后更有可能接受疫苗接种的患者。
{"title":"Predictors of Human Papillomavirus Vaccination in the Postpartum Period for Individuals Aged 18-26.","authors":"Christine G T Nguyen, Ava Mandelbaum, Lucy Ward, Katherine Bolten, Keenan Yanit, Jessica Currier, Amanda S Bruegl","doi":"10.1089/jwh.2024.0551","DOIUrl":"https://doi.org/10.1089/jwh.2024.0551","url":null,"abstract":"<p><p><b><i>Background:</i></b> Human papillomavirus (HPV) vaccination during the postpartum period is an opportunity for vaccine eligible individuals to be vaccinated. <b><i>Objective:</i></b> Identify predictors of vaccine acceptance in the postpartum period among patients aged 18-26. <b><i>Study Design:</i></b> A retrospective chart review was conducted to evaluate the rate of HPV vaccination to eligible postpartum patients aged 18-26 who delivered between January 2021 and May 2023 at our institution. Clinical and demographic data were extracted. Comparisons were made between fully vaccinated individuals and those who were unvaccinated or incompletely vaccinated. Variables significantly associated with vaccination status or acceptance were included in a multivariable logistic regression model. <b><i>Results:</i></b> Of the 1,130 patients who met the study inclusion criteria, 42.1% were eligible for postpartum HPV vaccination. The average age was 23 years, the majority White (74.5%), and English speaking (93.1%). Nineteen percent of eligible patients accepted HPV vaccination, with differences between those who accepted or declined the vaccine identified in: preferred language, tobacco use, delivering provider's specialty, and receiving any vaccination during pregnancy. Spanish-speaking patients had >5× the odds of accepting the vaccine compared with English-speaking patients. Smokers, patients delivered by a family medicine provider, and those who accepted any vaccine during pregnancy had more than twice the odds of receiving the vaccine postpartum. <b><i>Conclusion(s):</i></b> The postpartum period remains an opportunity to provide HPV vaccination. Our study identified patients less likely to be vaccinated prior to delivery, as well as patients who are more likely to accept vaccinations postpartum.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cancer Diagnosis During Pregnancy and Livebirth Outcomes in the Adolescent and Young Adult Horizon Study. 青少年地平线研究》(Adolescent and Young Adult Horizon Study)中的孕期癌症诊断与活产结果。
IF 3 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-09-05 DOI: 10.1089/jwh.2024.0064
Caroline Cochrane, Chelsea Anderson, Sara Mitra, Laura Green, Christopher D Baggett, Jennifer E Mersereau, Darios Getahun, Marilyn L Kwan, Chun R Chao, Lawrence H Kushi, Hazel B Nichols

Objective: To describe patterns of cancer treatment and live birth outcomes that followed a cancer diagnosis during pregnancy. Study Design: The Adolescent and Young Adult (AYA) Horizon Study is an observational study evaluating outcomes in survivors of the five most common types of cancer in this age group (15-39 years old). Of the 23,629 individuals identified diagnosed with breast, lymphoma, thyroid, melanoma, or gynecological cancer in North Carolina (2000-2015) and California (2004-2016), we identified 555 live births to individuals who experienced cancer diagnosis during pregnancy. Births to individuals diagnosed with cancer during pregnancy were matched ∼1:5 on maternal age and year of delivery to live births to individuals without a cancer diagnosis (N = 2,667). Multivariable Poisson regression was used to compare birth outcomes between pregnancies affected by a cancer diagnosis and unaffected matched pregnancies. Results: Cancer diagnosis during pregnancy was associated with an increased risk of preterm delivery (prevalence ratio [PR] 2.70; 95% confidence interval [CI] 2.24, 3.26); very preterm delivery (PR 1.74; 95% CI 1.12, 2.71); induction of labor (PR 1.48; 95% CI 1.27, 1.73); low birth weight (PR 1.97; 95% CI 1.55, 2.50); and cesarean delivery (PR 1.18; 95% CI 1.04, 1.34) but not associated with low Apgar score (PR 0.90; 95% CI 0.39, 2.06). In our sample, 41% of patients received chemotherapy, half of whom initiated chemotherapy during pregnancy, and 86% received surgery, 58% of whom had surgery during pregnancy. Of the 19% who received radiation, all received radiation treatment following pregnancy. Conclusion: We identified an increased risk of birth outcomes, including preterm and very preterm delivery, induction of labor, low birth weight, and cesarean delivery, to those experiencing a cancer diagnosis during pregnancy. This analysis contributes to the available evidence for those experiencing a cancer diagnosis during pregnancy.

目的描述怀孕期间确诊癌症后的癌症治疗模式和活产结果。研究设计:青少年地平线研究(AYA Horizon Study)是一项观察性研究,旨在评估该年龄组(15-39 岁)最常见的五种癌症幸存者的治疗效果。在北卡罗来纳州(2000-2015 年)和加利福尼亚州(2004-2016 年)已确诊的 23629 名乳腺癌、淋巴瘤、甲状腺癌、黑色素瘤或妇科癌症患者中,我们发现有 555 名活产婴儿在怀孕期间被诊断出患有癌症。怀孕期间确诊癌症的活产婴儿与未确诊癌症的活产婴儿(N = 2,667)在母亲年龄和分娩年份上进行了 1:5 的匹配。使用多变量泊松回归比较受癌症诊断影响的妊娠与未受影响的匹配妊娠的出生结果。结果显示孕期癌症诊断与早产(患病率比 [PR] 2.70;95% 置信区间 [CI]2.24,3.26)、极早产(患病率比 [PR] 1.74;95% 置信区间 [CI]1.12,2.71)、引产(患病率比 [PR] 2.70;95% 置信区间 [CI]2.24,3.26)、早产风险增加有关。71);引产(PR 1.48;95% CI 1.27,1.73);低出生体重(PR 1.97;95% CI 1.55,2.50);剖宫产(PR 1.18;95% CI 1.04,1.34),但与低 Apgar 评分(PR 0.90;95% CI 0.39,2.06)无关。在我们的样本中,41%的患者接受了化疗,其中半数在孕期开始化疗,86%的患者接受了手术,其中58%的患者在孕期接受了手术。在接受放射治疗的 19% 患者中,所有患者都是在怀孕后接受的放射治疗。结论我们发现,在怀孕期间被诊断出患有癌症的孕妇的分娩风险会增加,包括早产和极早产、引产、低出生体重和剖宫产。这项分析为孕期诊断出癌症的孕妇提供了更多证据。
{"title":"Cancer Diagnosis During Pregnancy and Livebirth Outcomes in the Adolescent and Young Adult Horizon Study.","authors":"Caroline Cochrane, Chelsea Anderson, Sara Mitra, Laura Green, Christopher D Baggett, Jennifer E Mersereau, Darios Getahun, Marilyn L Kwan, Chun R Chao, Lawrence H Kushi, Hazel B Nichols","doi":"10.1089/jwh.2024.0064","DOIUrl":"https://doi.org/10.1089/jwh.2024.0064","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To describe patterns of cancer treatment and live birth outcomes that followed a cancer diagnosis during pregnancy. <b><i>Study Design:</i></b> The Adolescent and Young Adult (AYA) Horizon Study is an observational study evaluating outcomes in survivors of the five most common types of cancer in this age group (15-39 years old). Of the 23,629 individuals identified diagnosed with breast, lymphoma, thyroid, melanoma, or gynecological cancer in North Carolina (2000-2015) and California (2004-2016), we identified 555 live births to individuals who experienced cancer diagnosis during pregnancy. Births to individuals diagnosed with cancer during pregnancy were matched ∼1:5 on maternal age and year of delivery to live births to individuals without a cancer diagnosis (<i>N</i> = 2,667). Multivariable Poisson regression was used to compare birth outcomes between pregnancies affected by a cancer diagnosis and unaffected matched pregnancies. <b><i>Results:</i></b> Cancer diagnosis during pregnancy was associated with an increased risk of preterm delivery (prevalence ratio [PR] 2.70; 95% confidence interval [CI] 2.24, 3.26); very preterm delivery (PR 1.74; 95% CI 1.12, 2.71); induction of labor (PR 1.48; 95% CI 1.27, 1.73); low birth weight (PR 1.97; 95% CI 1.55, 2.50); and cesarean delivery (PR 1.18; 95% CI 1.04, 1.34) but not associated with low Apgar score (PR 0.90; 95% CI 0.39, 2.06). In our sample, 41% of patients received chemotherapy, half of whom initiated chemotherapy during pregnancy, and 86% received surgery, 58% of whom had surgery during pregnancy. Of the 19% who received radiation, all received radiation treatment following pregnancy. <b><i>Conclusion:</i></b> We identified an increased risk of birth outcomes, including preterm and very preterm delivery, induction of labor, low birth weight, and cesarean delivery, to those experiencing a cancer diagnosis during pregnancy. This analysis contributes to the available evidence for those experiencing a cancer diagnosis during pregnancy.</p>","PeriodicalId":17636,"journal":{"name":"Journal of women's health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of women's health
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1