Background: PPE is a tool used to protect yourself or the body against the dangers of work accidents. The factors that influence adherence are K3 training, knowledge, behavior, age, gender. The Pharmacy Installation is a part of the hospital that manages the hospital's pharmaceutical needs, medicines, (BMHP), and medical devices. handling and controlling B3 as well as hospital injection drugs which of course have a risk of exposure to hazardous biological substances (biohazard). The purpose of this study was to analyze the factors associated with the compliance of pharmacy installation staff with the use of PPE at Kisaran Regional Hospital in 2021.Methods: This type of research used quantitative research using a cross sectional approach. The number of samples in this study were 30 people. The sample was determined by a simple technique of selecting the sample using purposive sampling. The results of the study: The data was collected using a questionnaire sheet and then processed using a statistical computer program with the chi square test with a significance level of α = 0.05 (95%). The results of the study found that the relationship of compliance with PPE use with age (p = 0.002 <α 0.05), gender (p = 0.127> α 0.05), K3 training (p = 0.004 <α 0.05), Knowledge (p = 0.018 <α 0.05) and Behavior (p = 0.011 <α 0.05). It is recommended for Kisaran Hospital to further improve the Compliance with the Use of PPE, especially for Pharmacy Installation employees.
{"title":"ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN KEPATUHAN PEGAWAI INSTALASI FARMASI DENGAN PENGGUNAAN ALAT PELINDUNG DIRI ( APD) DI RSUD KISARAN TAHUN 2021","authors":"S. Sulasmi","doi":"10.36656/jpfh.v4i1.759","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.759","url":null,"abstract":"Background: PPE is a tool used to protect yourself or the body against the dangers of work accidents. The factors that influence adherence are K3 training, knowledge, behavior, age, gender. The Pharmacy Installation is a part of the hospital that manages the hospital's pharmaceutical needs, medicines, (BMHP), and medical devices. handling and controlling B3 as well as hospital injection drugs which of course have a risk of exposure to hazardous biological substances (biohazard). The purpose of this study was to analyze the factors associated with the compliance of pharmacy installation staff with the use of PPE at Kisaran Regional Hospital in 2021.Methods: This type of research used quantitative research using a cross sectional approach. The number of samples in this study were 30 people. The sample was determined by a simple technique of selecting the sample using purposive sampling. The results of the study: The data was collected using a questionnaire sheet and then processed using a statistical computer program with the chi square test with a significance level of α = 0.05 (95%). The results of the study found that the relationship of compliance with PPE use with age (p = 0.002 <α 0.05), gender (p = 0.127> α 0.05), K3 training (p = 0.004 <α 0.05), Knowledge (p = 0.018 <α 0.05) and Behavior (p = 0.011 <α 0.05). It is recommended for Kisaran Hospital to further improve the Compliance with the Use of PPE, especially for Pharmacy Installation employees.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78900089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Leaf suji (Dracaena angustifolia) is a native plant of Indonesia that is used as a natural food coloring. However, ethnobotany and pharmacologicalreviews reveaed that this plant had potential as amedicinal ingredient one of them is for anti-inflamatory because it contains saponins that can reduce swelling. Methods: The objective of thE study to determine the gel from suji leaf extract works effectively as an anti-inflmatory against the feet of white male rays and to determine at what concentration the gel preparation from suji leaf ekstract is good as an anti-inflamatory. The method of the study used experimental. The results of the study: The gel preparation of suji leaf extract works effectively as an anti- inflamatory because it can inhibit inflamation in the feet of male white wistar rats well and the concentration of carrageenan induction, which is at a concentration of 20%. Keyword : Gel preparation, daun suji, anti-inflamatory
{"title":"UJI FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN PACAR (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus DAN Pseudomonas aeruginosa","authors":"D. Simorangkir, Linta Meliala","doi":"10.36656/jpfh.v4i1.766","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.766","url":null,"abstract":"Background: Leaf suji (Dracaena angustifolia) is a native plant of Indonesia that is used as a natural food coloring. However, ethnobotany and pharmacologicalreviews reveaed that this plant had potential as amedicinal ingredient one of them is for anti-inflamatory because it contains saponins that can reduce swelling. \u0000Methods: The objective of thE study to determine the gel from suji leaf extract works effectively as an anti-inflmatory against the feet of white male rays and to determine at what concentration the gel preparation from suji leaf ekstract is good as an anti-inflamatory. The method of the study used experimental. \u0000The results of the study: The gel preparation of suji leaf extract works effectively as an anti- inflamatory because it can inhibit inflamation in the feet of male white wistar rats well and the concentration of carrageenan induction, which is at a concentration of 20%. \u0000Keyword : Gel preparation, daun suji, anti-inflamatory","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78912584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The krokot is a weed that usually grows in plantations. In scientific language, purslane is called Portulaca oleracea L. Purslane is well-known as a nutritious plant in several countries such as China, Mexico, and Greece. In Indonesia, purslane is also known to have uses, or a substitute for ginseng. This aims of the study to determine the effectiveness of purslane herb ethanol extract ointment on wound healing in white rats. This research was conducted using an experimental method. In this study, phytochemical screening and simplicia characterization were carried out. Incision wound healing effect was tested on 25 male white rats with 5 treatment subgroups, namely positive control, negative control, purslane herb ethanol extract ointment 10%, purslane herb ethanol extract ointment 20%, purslane herb ethanol extract ointment 30%. The ointment base used is Vaseline album, liquid paraffin, and solid paraffin. All formulations of purslane herb 10%, 20% and 30%, met the requirements for evaluation of ointment preparations. Phytochemical screening results showed positive containing flavonoids, tannins and saponins. The results of the characterization of purslane herb simplicia powder obtained water content of 8.37%, water soluble extract content of 11.35%, ethanol soluble extract content of 10.99%, total ash content of 7.46% and acid insoluble ash content of 0.88%. The average results of observation of incision wounds in white rats were concentrations of 10% (22 mm) for 14 days, 20% (0.1 mm) for 14 days, 30% (0.04 mm) for 14 days. While the positive control (betadine ointment) was (0 mm) and the negative control (ointment base) was (0.42 mm). It can be concluded that purslane herb ethanol extract can provide effectiveness and antioxidants for wound healing in white rats. The purslane herb 30% ethanol extract has almost comparable effectiveness with betadine ointment in healing incisional wounds in white rats.
{"title":"UJI EFEKTIVITAS EKSTRAK ETANOL HERBA KROKOT (Portulaca oleracea L.) SECARA Topical UNTUK Reepitelisasi PENYEMBUHAN LUKA INSISI PADA TIKUS PUTIH (Rattus norvegicus)","authors":"Rani Ardiani","doi":"10.36656/jpfh.v4i1.750","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.750","url":null,"abstract":"The krokot is a weed that usually grows in plantations. In scientific language, purslane is called Portulaca oleracea L. Purslane is well-known as a nutritious plant in several countries such as China, Mexico, and Greece. In Indonesia, purslane is also known to have uses, or a substitute for ginseng. This aims of the study to determine the effectiveness of purslane herb ethanol extract ointment on wound healing in white rats. This research was conducted using an experimental method. In this study, phytochemical screening and simplicia characterization were carried out. Incision wound healing effect was tested on 25 male white rats with 5 treatment subgroups, namely positive control, negative control, purslane herb ethanol extract ointment 10%, purslane herb ethanol extract ointment 20%, purslane herb ethanol extract ointment 30%. The ointment base used is Vaseline album, liquid paraffin, and solid paraffin. All formulations of purslane herb 10%, 20% and 30%, met the requirements for evaluation of ointment preparations. Phytochemical screening results showed positive containing flavonoids, tannins and saponins. The results of the characterization of purslane herb simplicia powder obtained water content of 8.37%, water soluble extract content of 11.35%, ethanol soluble extract content of 10.99%, total ash content of 7.46% and acid insoluble ash content of 0.88%. The average results of observation of incision wounds in white rats were concentrations of 10% (22 mm) for 14 days, 20% (0.1 mm) for 14 days, 30% (0.04 mm) for 14 days. While the positive control (betadine ointment) was (0 mm) and the negative control (ointment base) was (0.42 mm). It can be concluded that purslane herb ethanol extract can provide effectiveness and antioxidants for wound healing in white rats. The purslane herb 30% ethanol extract has almost comparable effectiveness with betadine ointment in healing incisional wounds in white rats.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82956749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Indonesia is a country rich in natural resources that can be used as traditional medicine. Pacar leaf extract (Lawsonia inermis L.) can be formulated into ointment preparations, can inhibit the growth of staphylococcus aureus (SA) and pseudomonas aeruginosa (PA) bacteria and determine the best inhibitory concentration. Methods: This research method was experimental, the extract was obtained by maceration method with 80% ethanol solvent, then ointment was made using adeps lanae base, vaseline album and Pacar leaf extract ointment hadcombination concentrations 8%, 12% and 16%. The results of the study: The results showed that Pacar Leaf Extract (SEEDP)could be formulated as an ointment preparation and met the requirements for quality testing of ointment preparations, including characterization tests and phytochemical screening tests. The results of the antibacterial activity test showed that the formulation of the ointment preparations of Pacar Extract with concentrations of 8%, 12% and 16% could inhibit the growth of bacteria and good inhibition of 16% with an average diameter of bacteria (SA). 11.93 mm and bacteria (PA) 17.2 mm.It was concluded that the higher the concentration of the extract, the greater the inhibition given. The preparation of pacar leaf extract ointment with concentrations of 8%, 12% and 16% was the best ointment in inhibiting the growth of bacteria (SA) and (PA)
{"title":"UJI FORMULASI SEDIAAN SALEP EKSTRAK ETANOL DAUN PACAR (Lawsonia inermis L.) TERHADAP BAKTERI Staphylococcus aureus DAN Pseudomonas aeruginosa","authors":"Nina Irmayanti Harahap","doi":"10.36656/jpfh.v4i1.767","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.767","url":null,"abstract":"Background: Indonesia is a country rich in natural resources that can be used as traditional medicine. Pacar leaf extract (Lawsonia inermis L.) can be formulated into ointment preparations, can inhibit the growth of staphylococcus aureus (SA) and pseudomonas aeruginosa (PA) bacteria and determine the best inhibitory concentration. \u0000Methods: This research method was experimental, the extract was obtained by maceration method with 80% ethanol solvent, then ointment was made using adeps lanae base, vaseline album and Pacar leaf extract ointment hadcombination concentrations 8%, 12% and 16%. \u0000The results of the study: The results showed that Pacar Leaf Extract (SEEDP)could be formulated as an ointment preparation and met the requirements for quality testing of ointment preparations, including characterization tests and phytochemical screening tests. The results of the antibacterial activity test showed that the formulation of the ointment preparations of Pacar Extract with concentrations of 8%, 12% and 16% could inhibit the growth of bacteria and good inhibition of 16% with an average diameter of bacteria (SA). 11.93 mm and bacteria (PA) 17.2 mm.It was concluded that the higher the concentration of the extract, the greater the inhibition given. The preparation of pacar leaf extract ointment with concentrations of 8%, 12% and 16% was the best ointment in inhibiting the growth of bacteria (SA) and (PA) \u0000 ","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88457196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Agustin, Diana parmaning Comparison of antidiabetic effectiveness tests against crushed bay leaves (Syzygium polyanthum W) and purple sweet potato leaves (Ipomoea batatas L) in mice in 2021. (Supervised by: apt. Bunga Rimta Barus, S.farm.,M.Si ) Diabetes mellitus is a constant metabolic infection portrayed by an expansion in blood glucose levels that can be treated with customary medication got from plants. One illustration of a plant that can decrease blood glucose levels is inlet leaf and purple yam leaf which contain flavonoids to bring down blood glucose by expanding cell affectability to insulin and expanding insulin in pancreatic cells. To decide the impact of the blend of cove leaf concentrate and yam leaf in bringing blood glucose levels contrasted down with glibenclamide. The trial study utilized 15 mice which were initiated by alloxan and partitioned into 5 gatherings. Gathering 1 (negative control) CMC Na 1%, bunch 2 (positive control) glibenclamide at a portion of 0.65 mg/kgBB, bunch 3 a solitary cove leaf remove at a portion of 100 mg/kgBB, bunch 4 a solitary purple yam leaf separate at a portion of 200 mg/kg. kgBB, bunch 5 blend of straight leaf separate at a portion of 150 mg/kgBB and purple yam leaf extricate at a portion of 150 mg/kgBB. Extraction utilizing maceration strategy with 96% ethanol dissolvable. From the aftereffects of the investigation, every treatment bunch encountered a lessening in blood glucose levels. Of the 5 treatment gatherings, the best decrease in blood glucose levels was the three mix gatherings. Among the three mix gatherings, the mix portion of 150 mg/kgBB of inlet leaves and 150 mg/kgBB of purple yam leaves was the best contrasted with glibenclamide in bringing down blood glucose levels.Conclusion: The blend of sound leaf concentrate and purple yam leaf has a more successful impact on bringing down blood glucose levels than glibenclamide and its single concentrate.
{"title":"PERBANDINGAN UJI EFEKTIVITAS ANTIDIABETES TERHADAP LUMATAN DAUN SALAM (Syzygium polyanthum Wight) DAN DAUN UBI JALAR UNGU (Ipomoea batatas L.) PADA MENCIT TAHUN 2021","authors":"Angga Nugraha Sanjaya, Bunga Rimta Barus","doi":"10.36656/jpfh.v4i1.762","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.762","url":null,"abstract":"Background: Agustin, Diana parmaning Comparison of antidiabetic effectiveness tests against crushed bay leaves (Syzygium polyanthum W) and purple sweet potato leaves (Ipomoea batatas L) in mice in 2021. (Supervised by: apt. Bunga Rimta Barus, S.farm.,M.Si ) \u0000Diabetes mellitus is a constant metabolic infection portrayed by an expansion in blood glucose levels that can be treated with customary medication got from plants. One illustration of a plant that can decrease blood glucose levels is inlet leaf and purple yam leaf which contain flavonoids to bring down blood glucose by expanding cell affectability to insulin and expanding insulin in pancreatic cells. To decide the impact of the blend of cove leaf concentrate and yam leaf in bringing blood glucose levels contrasted down with glibenclamide. The trial study utilized 15 mice which were initiated by alloxan and partitioned into 5 gatherings. Gathering 1 (negative control) CMC Na 1%, bunch 2 (positive control) glibenclamide at a portion of 0.65 mg/kgBB, bunch 3 a solitary cove leaf remove at a portion of 100 mg/kgBB, bunch 4 a solitary purple yam leaf separate at a portion of 200 mg/kg. kgBB, bunch 5 blend of straight leaf separate at a portion of 150 mg/kgBB and purple yam leaf extricate at a portion of 150 mg/kgBB. Extraction utilizing maceration strategy with 96% ethanol dissolvable. From the aftereffects of the investigation, every treatment bunch encountered a lessening in blood glucose levels. Of the 5 treatment gatherings, the best decrease in blood glucose levels was the three mix gatherings. Among the three mix gatherings, the mix portion of 150 mg/kgBB of inlet leaves and 150 mg/kgBB of purple yam leaves was the best contrasted with glibenclamide in bringing down blood glucose levels.Conclusion: The blend of sound leaf concentrate and purple yam leaf has a more successful impact on bringing down blood glucose levels than glibenclamide and its single concentrate.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74222183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gel hand sanitizer telah banyak digunakan sebagai salah satu cara untuk menjaga kesehatan dan kebersihan tangan yang praktis dan mudah dibawa. Umumnya gel handsanitizer mengandung senyawa alkohol sebagai antiseptik untuk membunuh bakteri, tetapi penggunaan gel antiseptik yang mengandung alkohol dalam jangka panjang dapat menimbulkan iritasi. Oleh karena itu, diperlukan bahan alternatif alami yang ramah di kulit. dan tidak mengiritasi kulit,.salah satu tanaman yang memiliki daya antibakteri adalah daun lidah mertua (sansevieria trifasciata prain). Tujuan penelitian ini untuk mengetahui formulasi dan uji sifat fisik gel handsanitizer dari ekstrak daun lidah mertua (sansevieria trifasciata prain). Penelitian ini merupakan penelitian eksperimen dengan data hasil penelitian disajikan secara deskriptif. Gel dibuat dalam tiga formula dengan kosentrasi yang berbeda yaitu 10%, 20%, 30%. Evaluasi fisik gel yang dilakukan meliputi uji organoleptik, homogenitas, daya lekat, pH, viskositas, dan hedonik. Hasil evaluasi menunjukan formula 1 (10%) dan formula 2 (20%) dan formula 3 (30%). memenuhi semua syarat pada evaluasi sifat fisik gel yang meliputi uji organoleptik, homogenitas, daya lekat, pH, viskositas, dan hedonik.
{"title":"Formulasi Dan Uji Sifat Fisik Gel Hand Sanitizer Ekstrak Etanol Daun Lidah Mertua(Sansevieria Trifasciata Prain)","authors":"B. Barus","doi":"10.36656/jpfh.v4i1.763","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.763","url":null,"abstract":"Gel hand sanitizer telah banyak digunakan sebagai salah satu cara untuk menjaga kesehatan dan kebersihan tangan yang praktis dan mudah dibawa. Umumnya gel handsanitizer mengandung senyawa alkohol sebagai antiseptik untuk membunuh bakteri, tetapi penggunaan gel antiseptik yang mengandung alkohol dalam jangka panjang dapat menimbulkan iritasi. Oleh karena itu, diperlukan bahan alternatif alami yang ramah di kulit. dan tidak mengiritasi kulit,.salah satu tanaman yang memiliki daya antibakteri adalah daun lidah mertua (sansevieria trifasciata prain). Tujuan penelitian ini untuk mengetahui formulasi dan uji sifat fisik gel handsanitizer dari ekstrak daun lidah mertua (sansevieria trifasciata prain). Penelitian ini merupakan penelitian eksperimen dengan data hasil penelitian disajikan secara deskriptif. Gel dibuat dalam tiga formula dengan kosentrasi yang berbeda yaitu 10%, 20%, 30%. Evaluasi fisik gel yang dilakukan meliputi uji organoleptik, homogenitas, daya lekat, pH, viskositas, dan hedonik. Hasil evaluasi menunjukan formula 1 (10%) dan formula 2 (20%) dan formula 3 (30%). memenuhi semua syarat pada evaluasi sifat fisik gel yang meliputi uji organoleptik, homogenitas, daya lekat, pH, viskositas, dan hedonik.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79572514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: the Sapodilla leaves (Manilkara zapota L.) contain chemical compounds of tannins and flavonoids which have antidiarrheal activity. Tannins are astringent and flavonoids inhibit intestinal motility which can reduce fluid and electrolytes. Methods: This purpose research is to determine the effectiveness and comparison of sapodilla leaf extract syrup with Diapet Kids syrup as antidiarrheal against white mice induced by castor oil. The research used experimental method, the sample was macerated using 70% ethanol as solvent. The thick extract was formulated in syrup dosage form, and stability test was carried out. The syrup doses used were 60 mg/kg BW, 90 mg/kg BW, and 120 mg/kg BW, syrup without extract as a negative control and Diapet Kids syrup as a comparison syrup. The effectiveness of antidiarrhea was carried out by using the diarrhea protection method for 6 hours and comparing the effectiveness of the sapodilla leaf extract syrup with the Diapet Kids syrup. The results of research : is showed that the stability of sapodilla leaf extract syrup met the standard requirements. The data analysis using one way ANOVA then continued with Tukey HSD test. The antidiarrheal activity of sapodilla leaf extract syrup at 90 and 120 mg/kg BW and Diapet Kids syrup have significant different with positive control and syrup of sapodilla leaf extract at 60 mg/kg BW dose (p < 0.05). The comparison of syrup of sapodilla leaf extract dose of 120 mg/kg BW with syrup Diapet Kids was not in significantly difference (p > 0.05). The Sapodilla leaf extract syrup at 90 and 120 mg/kg BW had antidiarrheal activity and Sapodilla leaf extract syrup at 120 mg/kg BW had no significant difference with Diapet Kids syrup (p > 0.05).
{"title":"PERBANDINGAN SEDIAAN SIRUP ANTIDIARE EKSTRAK DAUN SAWO (Manilkara zapota L.) DENGAN SEDIAAN SIRUP ANTIDIARE DI PASARAN TERHADAP MENCIT PUTIH (Mus musculus L.)","authors":"Linta Meliala, Anggun Syafitri","doi":"10.36656/jpfh.v4i1.746","DOIUrl":"https://doi.org/10.36656/jpfh.v4i1.746","url":null,"abstract":"Background: the Sapodilla leaves (Manilkara zapota L.) contain chemical compounds of tannins and flavonoids which have antidiarrheal activity. Tannins are astringent and flavonoids inhibit intestinal motility which can reduce fluid and electrolytes. Methods: This purpose research is to determine the effectiveness and comparison of sapodilla leaf extract syrup with Diapet Kids syrup as antidiarrheal against white mice induced by castor oil. The research used experimental method, the sample was macerated using 70% ethanol as solvent. The thick extract was formulated in syrup dosage form, and stability test was carried out. The syrup doses used were 60 mg/kg BW, 90 mg/kg BW, and 120 mg/kg BW, syrup without extract as a negative control and Diapet Kids syrup as a comparison syrup. The effectiveness of antidiarrhea was carried out by using the diarrhea protection method for 6 hours and comparing the effectiveness of the sapodilla leaf extract syrup with the Diapet Kids syrup. The results of research : is showed that the stability of sapodilla leaf extract syrup met the standard requirements. The data analysis using one way ANOVA then continued with Tukey HSD test. The antidiarrheal activity of sapodilla leaf extract syrup at 90 and 120 mg/kg BW and Diapet Kids syrup have significant different with positive control and syrup of sapodilla leaf extract at 60 mg/kg BW dose (p < 0.05). The comparison of syrup of sapodilla leaf extract dose of 120 mg/kg BW with syrup Diapet Kids was not in significantly difference (p > 0.05). The Sapodilla leaf extract syrup at 90 and 120 mg/kg BW had antidiarrheal activity and Sapodilla leaf extract syrup at 120 mg/kg BW had no significant difference with Diapet Kids syrup (p > 0.05).","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90892538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daun Bau-Bau (Chromolanea odorata (L) King & H Robins) mengandung senyawa minyak atsiri, flavonoid, alkaloid, fenol, saponin, dan tannin. Temu putih (Curcuma zedoria (Berog.)Rosc) mengandung kurkumin, tritepenoid, flavonoida, saponin dan minyak astiri. Tujuan penelitian ini untuk membandingkan efektivitas Ekstrak Etanol Daun Bau-Bau dan Ekstrak Etanol Rimpang Temuputih. Ekstraksi sampel menggunakan etanol 96%. Hasil ekstraksi dibagi 7 kelompok konsentrasi yaitu 25%,15%, 10% dan Aquadest sebagai kontrol negatif.Menurut Hasil Analisis Data Anova One Way (Uji Tuckeys B) Diameter luka bakar dari hari pertama sampai ke 14 hari pengamatan mengalami penurunan, kelompok kelinci yang diberi perlakuan dengan ekstrak daun bau-bau konsentrasi 25% pada hari ke- 14 diameter luka bakar mengalami perubahan dengan efektifitas 2 cm (p=0,0). Pada kelompok ekstrak etanol temuputih konsentrasi 25% pada hari ke-14 diameter luka bakar mengalami perubahan dengan efektifitas 1,08 cm (p=0,64). Ekstrak Etanol Daun Bau-Bau Lebih Efektif untuk menyembuhkan luka bakar dibandingkan dengan Ekstrak Etanol Temu Putih.
{"title":"Perbandingan Konsentrasi Ekstrak Etanol Daun Bau-Bau (Chromolaena odorata (L.) King & H.E. Robins) Dan Ekstrak Etanol Temu Putih (Curcuma zedoria (Berog) Rosc) terhadap Penyembuhan Luka Bakar pada Kelinci","authors":"Bunga Rimta Barus","doi":"10.36656/JPFH.V3I2.638","DOIUrl":"https://doi.org/10.36656/JPFH.V3I2.638","url":null,"abstract":"Daun Bau-Bau (Chromolanea odorata (L) King & H Robins) mengandung senyawa minyak atsiri, flavonoid, alkaloid, fenol, saponin, dan tannin. Temu putih (Curcuma zedoria (Berog.)Rosc) mengandung kurkumin, tritepenoid, flavonoida, saponin dan minyak astiri. Tujuan penelitian ini untuk membandingkan efektivitas Ekstrak Etanol Daun Bau-Bau dan Ekstrak Etanol Rimpang Temuputih. Ekstraksi sampel menggunakan etanol 96%. Hasil ekstraksi dibagi 7 kelompok konsentrasi yaitu 25%,15%, 10% dan Aquadest sebagai kontrol negatif.Menurut Hasil Analisis Data Anova One Way (Uji Tuckeys B) Diameter luka bakar dari hari pertama sampai ke 14 hari pengamatan mengalami penurunan, kelompok kelinci yang diberi perlakuan dengan ekstrak daun bau-bau konsentrasi 25% pada hari ke- 14 diameter luka bakar mengalami perubahan dengan efektifitas 2 cm (p=0,0). Pada kelompok ekstrak etanol temuputih konsentrasi 25% pada hari ke-14 diameter luka bakar mengalami perubahan dengan efektifitas 1,08 cm (p=0,64). Ekstrak Etanol Daun Bau-Bau Lebih Efektif untuk menyembuhkan luka bakar dibandingkan dengan Ekstrak Etanol Temu Putih. \u0000 ","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82627843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hati ungu contain natural dyes derived from anthocyanins. Anthocyanin is a pigment that is classified into flavonoids which in general gives a specific color to plants. The natural color found in this purple liver plant can be used as a natural coloring agent in cosmetics. Hair dye cream preparations were chosen because they are popular and easy to use. The purpose of this study is to determine ethanol extracts of hati ungu can be made as a preparation for hair dye creams, and which formula gives the best color. The research method was carried out including making ethanol extract of hati ungu (Tradescantia pallida) by maceration using 96% ethanol.The results of research on 4 hair dye cream formulations, preparations met the test requirements. The results of the basting test on hair with a vulnerable time for 1-4 hours showed that at the fourth hour the results of hair coloring give a good color. In the color stability test of washing, after washing with shampoo fifteen times all four formulas have a fixed color up to 9 times washing. The results of color stability to sunlight show that after the hair is exposed to sunlight the color looks slightly changed, hair color becomes darker than before. From the results of the research the concentration of ethanol extract of hati ungu which gives the best purple color is ethanol extract cream of hati ungu 20%.
{"title":"FORMULASI KRIM PEWARNA RAMBUT EKSTRAK ETANOL DAUN HATI UNGU (Tradescantia pallida)","authors":"W. Wahyuni","doi":"10.36656/jpfh.v3i2.653","DOIUrl":"https://doi.org/10.36656/jpfh.v3i2.653","url":null,"abstract":"Hati ungu contain natural dyes derived from anthocyanins. Anthocyanin is a pigment that is classified into flavonoids which in general gives a specific color to plants. The natural color found in this purple liver plant can be used as a natural coloring agent in cosmetics. Hair dye cream preparations were chosen because they are popular and easy to use. The purpose of this study is to determine ethanol extracts of hati ungu can be made as a preparation for hair dye creams, and which formula gives the best color. The research method was carried out including making ethanol extract of hati ungu (Tradescantia pallida) by maceration using 96% ethanol.The results of research on 4 hair dye cream formulations, preparations met the test requirements. The results of the basting test on hair with a vulnerable time for 1-4 hours showed that at the fourth hour the results of hair coloring give a good color. In the color stability test of washing, after washing with shampoo fifteen times all four formulas have a fixed color up to 9 times washing. The results of color stability to sunlight show that after the hair is exposed to sunlight the color looks slightly changed, hair color becomes darker than before. From the results of the research the concentration of ethanol extract of hati ungu which gives the best purple color is ethanol extract cream of hati ungu 20%.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88468823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kecombrang (Etlingera elatior) leaves contain flavonoid compounds, saponins, alkoloid, and tannins. Based on the compounds owned kecombrang leaves can be used as a peel off gel mask. The purpose of this study was to make a peel off gel mask formulation of kecombrang (Etlingera elatior) leaf extract as a treatment for facial skin. The gel peel off mask formulation was made with 4 formulations, F0 = 0%, FI = 10%, FII = 15%, FIII = 20%. Extraction method is done using maceration method with 96% ethanol solvent. Evaluation of peel off gel mask preparations, including organoleptic tests (color, odor, shape), pH measurement of preparations, homogeneity test, dry time test, spreadability test. Peel off gel mask preparations that have effectiveness as treatments for facial skin are FIII formulations with a concentration of 15% that meet the evaluation test requirements, and positive control (Naturgo) which has had better effectiveness test results. The results of the evaluation test of peel off gel mask preparation, including organoleptic test (color, odor, shape), pH measurement of the preparation, homogeneity test, dry time test, dispersion test according to the gel preparation parameters.
{"title":"FORMULASI SEDIAAN MASKER GEL Peel-off EKSTRAK DAUN KECOMBRANG (Etlingera elatior) SEBAGAI PERAWATAN PADA KULIT WAJAH","authors":"B. Sembiring","doi":"10.36656/JPFH.V3I2.676","DOIUrl":"https://doi.org/10.36656/JPFH.V3I2.676","url":null,"abstract":"Kecombrang (Etlingera elatior) leaves contain flavonoid compounds, saponins, alkoloid, and tannins. Based on the compounds owned kecombrang leaves can be used as a peel off gel mask. The purpose of this study was to make a peel off gel mask formulation of kecombrang (Etlingera elatior) leaf extract as a treatment for facial skin. The gel peel off mask formulation was made with 4 formulations, F0 = 0%, FI = 10%, FII = 15%, FIII = 20%. Extraction method is done using maceration method with 96% ethanol solvent. Evaluation of peel off gel mask preparations, including organoleptic tests (color, odor, shape), pH measurement of preparations, homogeneity test, dry time test, spreadability test. Peel off gel mask preparations that have effectiveness as treatments for facial skin are FIII formulations with a concentration of 15% that meet the evaluation test requirements, and positive control (Naturgo) which has had better effectiveness test results. The results of the evaluation test of peel off gel mask preparation, including organoleptic test (color, odor, shape), pH measurement of the preparation, homogeneity test, dry time test, dispersion test according to the gel preparation parameters.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"353 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75494974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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