Antioxidants is contained in various types of fruit and vegetables included of juice tomatoes (Lycopersicum esculentum Mill)that have nutritional value and benefits for the body like lycopene, and vitamin C as antioxidants. Lycopene is function as a strong antioxidant to control free radical. Tumeric (Curcuma domestica Vall) is known have enough curcumin and strong antioxydants content too, and so it has some pharmacological effects. Tomatoes and Tumeric extract (EKSBT) can be made as pharmaceutical preparations in hand and body lotion (H&B lotion),because antioxidants are important components that are used for body protection from ultra violet light and can be applied in the form of a lotion. The purpose of this study was to saw the stability of the H&B lotion combination of that Variations.Combination tomatoes and turmeric extract formulated with concentrations lotion are of 5%, 10%, and 15%. The lotion of EKSBT these combination were evaluated some test there are organoleptic, homogeneity, pH test, spreadability, irritation and preference test.EKSBT combination can be formulated into lotion preparations. The various of all concentrations lotion EKSBT showed that stable during instorage, give a homogeneous yellow color with pH of 5-6 and a spread of 5-6 cm, does not irritate the skin and is preferably the volunteer.Physical stability EKSBT lotion test all concentration are stable, the preferred test of odor, easy to be smeared and moisturizing shows that the most preferred EKSBT lotion is the highest concentration 15%.
{"title":"FORMULASI DAN UJI STABILITAS LOTION SARI BUAH TOMAT (licopersicon esculentum mill) KOMBINASI KUNYIT (Curcuma domestica Vall) SEBAGAI PELEMBAB KULIT","authors":"Nina Irmayanti Harahap","doi":"10.36656/JPFH.V3I2.607","DOIUrl":"https://doi.org/10.36656/JPFH.V3I2.607","url":null,"abstract":"Antioxidants is contained in various types of fruit and vegetables included of juice tomatoes (Lycopersicum esculentum Mill)that have nutritional value and benefits for the body like lycopene, and vitamin C as antioxidants. Lycopene is function as a strong antioxidant to control free radical. Tumeric (Curcuma domestica Vall) is known have enough curcumin and strong antioxydants content too, and so it has some pharmacological effects. Tomatoes and Tumeric extract (EKSBT) can be made as pharmaceutical preparations in hand and body lotion (H&B lotion),because antioxidants are important components that are used for body protection from ultra violet light and can be applied in the form of a lotion. The purpose of this study was to saw the stability of the H&B lotion combination of that Variations.Combination tomatoes and turmeric extract formulated with concentrations lotion are of 5%, 10%, and 15%. The lotion of EKSBT these combination were evaluated some test there are organoleptic, homogeneity, pH test, spreadability, irritation and preference test.EKSBT combination can be formulated into lotion preparations. The various of all concentrations lotion EKSBT showed that stable during instorage, give a homogeneous yellow color with pH of 5-6 and a spread of 5-6 cm, does not irritate the skin and is preferably the volunteer.Physical stability EKSBT lotion test all concentration are stable, the preferred test of odor, easy to be smeared and moisturizing shows that the most preferred EKSBT lotion is the highest concentration 15%. ","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89448954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dragon fruit contain high antosianin, sources of antosianin can be optained from pink colored fruit and vegetables to red. The natural properties of antosianin can be used as natural dyes in cosmetic preparation were chosen because it is a cosmetic that is quite popular and most comfortable to use. The purpose of this research is to find out whether dragon fruit can be blush on, not irritated and to find out the best formulations. The methode of this research was done by making dragon fruit extract by maceration for 24 hours using etanol. The extract formulation used is 15%, 25%, and 40%. Ingridienst for making blush on include kaolin, parrafin liquid, zink oxyd, and talcum. Evaluation of blus on preparations include homogenty, pH, dispersion, irritation, polish and hedonic. The results of research 3 blush on formulation, the preparation met the homogenity test with no vissible coarse grains and particlesevently mixed. The pH of the preparation producted is still in the normal pH range of spearat evenly and easily attached to the skin, with each application three time polishing. Based on the favorite test after processing statistical data, formulation the most preferred panelish is blush on formulation 3. Key words: Dragon fruit, blush on, antosianin.
{"title":"FORMULASI EKSTRAK BUAH NAGA MERAH (Hylocereus polyrhizus ) SEBAGAI SEDIAAN PEMERAH PIPI (BLUSH ON)","authors":"Herviani Sari","doi":"10.36656/JPFH.V3I2.649","DOIUrl":"https://doi.org/10.36656/JPFH.V3I2.649","url":null,"abstract":"Dragon fruit contain high antosianin, sources of antosianin can be optained from pink colored fruit and vegetables to red. The natural properties of antosianin can be used as natural dyes in cosmetic preparation were chosen because it is a cosmetic that is quite popular and most comfortable to use. The purpose of this research is to find out whether dragon fruit can be blush on, not irritated and to find out the best formulations. The methode of this research was done by making dragon fruit extract by maceration for 24 hours using etanol. The extract formulation used is 15%, 25%, and 40%. Ingridienst for making blush on include kaolin, parrafin liquid, zink oxyd, and talcum. Evaluation of blus on preparations include homogenty, pH, dispersion, irritation, polish and hedonic. The results of research 3 blush on formulation, the preparation met the homogenity test with no vissible coarse grains and particlesevently mixed. The pH of the preparation producted is still in the normal pH range of spearat evenly and easily attached to the skin, with each application three time polishing. Based on the favorite test after processing statistical data, formulation the most preferred panelish is blush on formulation 3. \u0000Key words: Dragon fruit, blush on, antosianin.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73096768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives : The purpose of this study to determine the effect and dose of effective use of rhizome extract of turmeric as antidiarrhea in male mice induced castor oil and the use of rhizome extract of turmeric equivalent to Loperamid HCl. Method : This research method is carried out experimentally with the research stages of sample preparation, sample characterization, simplicia screening, preparation of extracts, preparation of animal experiments and testing of antidiarrheal effects in experimental animals. Results : The results showed that the results of phytochemical screening of simplicia powder and turmeric rhizome extract contained flavonoids and tannins. SPSS statistical test results (statistical package for the social science) continued with defference test of Duncan average, the duration of the occurrence of diarrhea showed that the control group of Loperamid HCl dose 1 mg/kg bw gave significant effect on turmeric rhizome extract at doses of 40 mg/ kg bw and doses 80 mg/kg bw. The shorter the time of diarrhea, the stronger the antidiarrheal effect. Conclusion : Turmeric rhizome extract dose 20 mg/kgbw showed that dose 20 mg/kgbw has antidiarrhea effect more than lower than Loperamid HCl dose 1 mg/kg bw. Turmeric rhizome extract dose 40 mg/kg bb has same effect with Loperamid HCl dose 1 mg/kgbb. And turmeric rhizome extract dose 80 mg/kgbb has effect more potencial that Loperamid HCl dose 1mg/kg bw. There is a relationship between the size of the dose with the antidiarrheal effect that occurs.
{"title":"UJI EFEK ANTIDIARE EKSTRAK RIMPANG KUNYIT (Curcuma domestica val.) PADA MENCIT JANTAN","authors":"Linta Meliala, W. Sari, P. Tarigan","doi":"10.36656/jpfh.v2i2.208","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.208","url":null,"abstract":"Objectives : The purpose of this study to determine the effect and dose of effective use of rhizome extract of turmeric as antidiarrhea in male mice induced castor oil and the use of rhizome extract of turmeric equivalent to Loperamid HCl. \u0000Method : This research method is carried out experimentally with the research stages of sample preparation, sample characterization, simplicia screening, preparation of extracts, preparation of animal experiments and testing of antidiarrheal effects in experimental animals. \u0000Results : The results showed that the results of phytochemical screening of simplicia powder and turmeric rhizome extract contained flavonoids and tannins. SPSS statistical test results (statistical package for the social science) continued with defference test of Duncan average, the duration of the occurrence of diarrhea showed that the control group of Loperamid HCl dose 1 mg/kg bw gave significant effect on turmeric rhizome extract at doses of 40 mg/ kg bw and doses 80 mg/kg bw. The shorter the time of diarrhea, the stronger the antidiarrheal effect. \u0000Conclusion : Turmeric rhizome extract dose 20 mg/kgbw showed that dose 20 mg/kgbw has antidiarrhea effect more than lower than Loperamid HCl dose 1 mg/kg bw. Turmeric rhizome extract dose 40 mg/kg bb has same effect with Loperamid HCl dose 1 mg/kgbb. And turmeric rhizome extract dose 80 mg/kgbb has effect more potencial that Loperamid HCl dose 1mg/kg bw. There is a relationship between the size of the dose with the antidiarrheal effect that occurs.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85327392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
African leaves (Gymnanthemum amygdalina Del.) and palm leaves (Elaeis guineensis Jacq.) which is contain flavonoid, saponin, alkaloid, and tannin can be used to decrease cholesterol levels and reduced the risk of cardiovascular disease. This study aims to determine the effect of EEDA dan EEDKS combination on blood cholesterol levels in hypercholesterolemic mice. Sample in this study was African leaves and palm leaves which were taken purposively without comparing samples from other regions, then extracted by maceration using ethanol 96%. The results of data analysis from the three EEDA and EEDKS groups effected cholesterol reduction due to the sig value <0.05. Based on ANOVA one way analysis of the five most effective treatments is simvastatin then dose 400-600mg/kgBB, dose 200-300mg/kgBB, dose 100-150mg/kgBB and CMC Na 1%. The combination of EEDA and EEDKS has an antihypercholesterol effect, the combination of EEDA and EEDKS has an antihypercholesterol effect that is comparable to the positive control, and the finding from this study that the most effective dosage of EEDA and EEDKS as antihypercholesterol is at dosage 400-600 mg/kgBB.
{"title":"UJI EFEKTIVITAS ANTIKOLESTEROL KOMBINASI EKSTRAK ETANOL DAUN AFRIKA (Gymnanthemum amygdalina Del.) DENGAN EKSTRAK ETANOL DAUN KELAPA SAWIT (Elaeis guineensis Jacq.) PADA TIKUS HIPERKOLESTEROL","authors":"Herviani Sari, Nurmaulia Nurmaulia, Wahyudi Wahyudi, Firdaus Fahdi","doi":"10.36656/jpfh.v2i2.206","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.206","url":null,"abstract":"African leaves (Gymnanthemum amygdalina Del.) and palm leaves (Elaeis guineensis Jacq.) which is contain flavonoid, saponin, alkaloid, and tannin can be used to decrease cholesterol levels and reduced the risk of cardiovascular disease. This study aims to determine the effect of EEDA dan EEDKS combination on blood cholesterol levels in hypercholesterolemic mice. Sample in this study was African leaves and palm leaves which were taken purposively without comparing samples from other regions, then extracted by maceration using ethanol 96%. The results of data analysis from the three EEDA and EEDKS groups effected cholesterol reduction due to the sig value <0.05. Based on ANOVA one way analysis of the five most effective treatments is simvastatin then dose 400-600mg/kgBB, dose 200-300mg/kgBB, dose 100-150mg/kgBB and CMC Na 1%. The combination of EEDA and EEDKS has an antihypercholesterol effect, the combination of EEDA and EEDKS has an antihypercholesterol effect that is comparable to the positive control, and the finding from this study that the most effective dosage of EEDA and EEDKS as antihypercholesterol is at dosage 400-600 mg/kgBB.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84463569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Inflammation is a protective response of the body from the injury of the cell. Edema is one of the inflammation symptoms. Drumstick (Moringa oleifera L.) contains flavonoid a major of a bioactive constituent. Flavonoids inhibit COX-2 in inflammatory in mice. Objective: This study aims to investigate and to determine the anti-inflammatory activity and its effective dose extract. Method: Experimental. The extract was prepared by maceration method using ethanol 80%. An anti-inflammatory activity test was performed in five different groups. Each group consisted of 5 rats. The 1st group (negative control) was given 0,5% CMC-Na suspension, the 2nd group (positive control) was given diclofenac sodium 2,25 mg/kg BW, the 3rd, 4th, and 5th groups were successively given the drumstick leaf extract as much as 100, 150, and 200 mg/kg BW. Each rat was then induced by 1% carrageenan and tested using the subplantar method. The inflamed paw volume was measured using plestymometer. The measurements were done for 3 hours long with intervals of 30 minutes. The data were statistically analyzed using ANOVA (Analysis of Variance). Results: The results showed that the negative control had a significant difference with the other treatment groups which did not show any anti-inflammatory effect. Conclusion: Extract of a drumstick at a dose of 200 mg/kg BW has a better anti-inflammatory effect than ethanolic of a drumstick at dose of 100, 150 mg/kg BW, but still under sodium diclofenac.
{"title":"UJI AKTIVITAS INFLAMASI EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) TERHADAP TIKUS PUTIH JANTAN (Galur wistar)","authors":"D. Simorangkir, Jenti Hutagalung, Palas Tarigan","doi":"10.36656/jpfh.v2i2.236","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.236","url":null,"abstract":"Background: Inflammation is a protective response of the body from the injury of the cell. Edema is one of the inflammation symptoms. Drumstick (Moringa oleifera L.) contains flavonoid a major of a bioactive constituent. Flavonoids inhibit COX-2 in inflammatory in mice. Objective: This study aims to investigate and to determine the anti-inflammatory activity and its effective dose extract. Method: Experimental. The extract was prepared by maceration method using ethanol 80%. An anti-inflammatory activity test was performed in five different groups. Each group consisted of 5 rats. The 1st group (negative control) was given 0,5% CMC-Na suspension, the 2nd group (positive control) was given diclofenac sodium 2,25 mg/kg BW, the 3rd, 4th, and 5th groups were successively given the drumstick leaf extract as much as 100, 150, and 200 mg/kg BW. Each rat was then induced by 1% carrageenan and tested using the subplantar method. The inflamed paw volume was measured using plestymometer. The measurements were done for 3 hours long with intervals of 30 minutes. The data were statistically analyzed using ANOVA (Analysis of Variance). Results: The results showed that the negative control had a significant difference with the other treatment groups which did not show any anti-inflammatory effect. Conclusion: Extract of a drumstick at a dose of 200 mg/kg BW has a better anti-inflammatory effect than ethanolic of a drumstick at dose of 100, 150 mg/kg BW, but still under sodium diclofenac. \u0000 \u0000 ","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81500534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahma Shufyani, Sara Yudistira, Muhammad Mabrur, Armaliza Permata Sari
Jackfruit leaf is (Artocarpus heterophyllus L) is one of the natural ingredients that can be used as a therapeutic treatment of acne. To facilitate its use the extract is made in the form of a cream. This study aims to determine the antibacterial activity of anti-acne cream jackfruit leaf extract against propionibacterium acne with concentrations of 30%, 50%, 70%, and 90%. Compounds that act as antibacterials on jackfruit leaves include flavonoids, tannins, saponins. This research method is an ANOVA one way method. The extraction method used is the maceration method. The tests include physical stability test and anti-acne activity test. Physical preparation stability test is carried out every 6 days for 3 weeks. While the anti-acne activity observation test was carried out on Propionibacterium acne bacteria. Based on the observation of organoleptic preparations of formulations 1 and 2 there was no change, while 3,4,5 there was a change. Anti- acne activity test showed that formulations 1 and 2 were more effective than formulations 3, 4, 5 with an average inhibition zone of 9.5 mm.
{"title":"FORMULASI KRIM EKSTRAK DAUN NANGKA (Artocarpus heterophyllus L.) TERHADAP BAKTERI Propionibacterium acne","authors":"Fahma Shufyani, Sara Yudistira, Muhammad Mabrur, Armaliza Permata Sari","doi":"10.36656/jpfh.v2i2.258","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.258","url":null,"abstract":"Jackfruit leaf is (Artocarpus heterophyllus L) is one of the natural ingredients that can be used as a therapeutic treatment of acne. To facilitate its use the extract is made in the form of a cream. This study aims to determine the antibacterial activity of anti-acne cream jackfruit leaf extract against propionibacterium acne with concentrations of 30%, 50%, 70%, and 90%. Compounds that act as antibacterials on jackfruit leaves include flavonoids, tannins, saponins. This research method is an ANOVA one way method. The extraction method used is the maceration method. The tests include physical stability test and anti-acne activity test. Physical preparation stability test is carried out every 6 days for 3 weeks. While the anti-acne activity observation test was carried out on Propionibacterium acne bacteria. Based on the observation of organoleptic preparations of formulations 1 and 2 there was no change, while 3,4,5 there was a change. Anti- acne activity test showed that formulations 1 and 2 were more effective than formulations 3, 4, 5 with an average inhibition zone of 9.5 mm.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86556153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ascorbic acid is one of the nutrients that acts as an antioxidant to effectively overcome free radicals that can damage cells or tissues, including protecting the lens from oxidative damage caused by radiation. Ascorbic acid is abundant in fruits and vegetables, one of which is chili and pappers.The purpose of this study was to determine the content of the content and differences in levels of ascorbic acid content in several types of chillies and peppers. The method used in this study is the Iodimetry method, because ascorbic acid is a reducing agent which is strong enough, easily oxidized and iodine is easily reduced. This is one of the requirements of the compound can be done by the Iodimetry method. This research included descriptive research, with samples of red chili, cayenne pepper, curly green chili, red peppers, yellow peppers and green peppers obtained in the market of the old deli and its surroundings. This research begins with making samples, then performs qualitative tests, making standard solutions and determining ascorbic acid levels. During the titration process replication is done 6 times to compare the results of each titration. The results showed levels of ascorbic acid Red Chilli = 0.1856%, Cayenne pepper = 0.0739%, Curly green Chili = 0.0882%, Red peppers = 0.1945%, Yellow paprika = 0.1886%, and Green peppers = 0.1631%. Conclusions showed that the highest ascorbic acid levels were found in red pappers samples which were 0.1945% and the lowest ascorbic acid levels were in the cayenne sample which was 0.0739%. Suggestions for future researchers should be continued with other parameters and samples.
{"title":"PENETAPAN KADAR VITAMIN C PADA BEBERAPA JENIS CABE (CAPSICUM ANNUM L.) DAN PAPRIKA (CAPSICUM ANNUM L. VAR. GROSUM) DENGAN METODE TITRASI IODIMETRI","authors":"B. Sembiring, Anggi Pramono Siregar","doi":"10.36656/jpfh.v2i2.219","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.219","url":null,"abstract":"Ascorbic acid is one of the nutrients that acts as an antioxidant to effectively overcome free radicals that can damage cells or tissues, including protecting the lens from oxidative damage caused by radiation. Ascorbic acid is abundant in fruits and vegetables, one of which is chili and pappers.The purpose of this study was to determine the content of the content and differences in levels of ascorbic acid content in several types of chillies and peppers. The method used in this study is the Iodimetry method, because ascorbic acid is a reducing agent which is strong enough, easily oxidized and iodine is easily reduced. This is one of the requirements of the compound can be done by the Iodimetry method. This research included descriptive research, with samples of red chili, cayenne pepper, curly green chili, red peppers, yellow peppers and green peppers obtained in the market of the old deli and its surroundings. This research begins with making samples, then performs qualitative tests, making standard solutions and determining ascorbic acid levels. During the titration process replication is done 6 times to compare the results of each titration. The results showed levels of ascorbic acid Red Chilli = 0.1856%, Cayenne pepper = 0.0739%, Curly green Chili = 0.0882%, Red peppers = 0.1945%, Yellow paprika = 0.1886%, and Green peppers = 0.1631%. Conclusions showed that the highest ascorbic acid levels were found in red pappers samples which were 0.1945% and the lowest ascorbic acid levels were in the cayenne sample which was 0.0739%. Suggestions for future researchers should be continued with other parameters and samples.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72940719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Senggani plants also have a reddish purple flower, ripe fruit will break the color purple and reddish brown beans. However, the utilization of senggani leaves is still not getting attention, therefore, to increase the economic value and utilization of this plant, senggani leaf can be formulated in the extract ointment of senggani leaf ethanol to healing the cut on the rabbit so it is expected to give healing effect on the rabbit wound.The purpose of this research is to know the concentration of ethanol extract of senggani leaf in the formulation of the ointment which is most effective in healing the rabbit wound in rabbit and to know the ointment ratio of ethanol extract of senggani leaves with betadine ointment .The samples in this study were extract from senggani leaf extracted by maceration using 80% ethanol solvent and formulated in ointment preparation using ingredients of adeps lanae and vaseline album. All data were tested statistically using ANOVA ONE WAY.Preparation of ointment extract of ethanol senggani leaf can accelerate the healing process of the wound and the most effective is the syrup leaf extract of 50% with an average healing for 11 days while betadine ointment does not experience healing until day 14.Indicating differences between treatment groups were more effective in healing of cuts on rabbits and 50% extracts of ethanol extracts of senggani leaf were more effective than with betadine ointment.
{"title":"EFEKTIVITAS PENYEMBUHAN LUKA SAYAT MENGGUNAKAN SALEP EKSTRAK ETANOL DAUN SENGGANI (Melastoma malabathricum L.) PADA KELINCI","authors":"Vera Estefania Kaban, Jessi Octavia Aritonang, Yulia Citra Hasibuan, Dian Ika Perbina Meliala","doi":"10.36656/jpfh.v2i2.207","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.207","url":null,"abstract":"Senggani plants also have a reddish purple flower, ripe fruit will break the color purple and reddish brown beans. However, the utilization of senggani leaves is still not getting attention, therefore, to increase the economic value and utilization of this plant, senggani leaf can be formulated in the extract ointment of senggani leaf ethanol to healing the cut on the rabbit so it is expected to give healing effect on the rabbit wound.The purpose of this research is to know the concentration of ethanol extract of senggani leaf in the formulation of the ointment which is most effective in healing the rabbit wound in rabbit and to know the ointment ratio of ethanol extract of senggani leaves with betadine ointment .The samples in this study were extract from senggani leaf extracted by maceration using 80% ethanol solvent and formulated in ointment preparation using ingredients of adeps lanae and vaseline album. All data were tested statistically using ANOVA ONE WAY.Preparation of ointment extract of ethanol senggani leaf can accelerate the healing process of the wound and the most effective is the syrup leaf extract of 50% with an average healing for 11 days while betadine ointment does not experience healing until day 14.Indicating differences between treatment groups were more effective in healing of cuts on rabbits and 50% extracts of ethanol extracts of senggani leaf were more effective than with betadine ointment.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72975095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunscreen is a cosmetic ingredient that can physically resist UV A and UV B rays. UV A radiation can cause brown color on the skin and UV B rays can cause skin burn. Although the skin has protection against sunlight, it is still necessary to use sunscreen on the skin. Substances Antioxidants are substances that at small concentrations can significantly inhibit oxidation on the substrate caused by free radicals. One plant that contains natural antioxidants is cocoa beans.To determine the value of Sun Protection Factor (SPF) from cocoa bean extract formulated in cream form and in combination with Avobenxone and Octyl Methoxycinnamate (OMC). Making cocoa bean extract was extracted by maceration using 80% ethanol solvent, making sunscreen extract of cocoa bean extract made in three formulations with concentrations of 10%, 15% and 20%, evaluating cream preparations and determining SPF values (Sun Protection Factor). using UV-Vis spectrophotometry.The results of the study showed differences in SPF values between cocoa bean extract creams. The concentration that has the highest SPF value is 20% with an SPF value of 15.22. The SPF value obtained from each formula is in the maximum category, the recommended value is 15.00. The best SPF value is found at a concentration of 20%, which is 15.22.
{"title":"FORMULASI DAN UJI AKTIVITAS KRIM TABIR SURYA EKSTRAK BIJI KAKAO (Theobroma cacao L.) DENGAN KOMBINASI AVOBENZONE DAN OCTYL METHOXYCINNAMATE","authors":"Dian Ika Perbina Meliala, W. Wahyudi, Nelva Nelva","doi":"10.36656/jpfh.v2i2.278","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.278","url":null,"abstract":"Sunscreen is a cosmetic ingredient that can physically resist UV A and UV B rays. UV A radiation can cause brown color on the skin and UV B rays can cause skin burn. Although the skin has protection against sunlight, it is still necessary to use sunscreen on the skin. Substances Antioxidants are substances that at small concentrations can significantly inhibit oxidation on the substrate caused by free radicals. One plant that contains natural antioxidants is cocoa beans.To determine the value of Sun Protection Factor (SPF) from cocoa bean extract formulated in cream form and in combination with Avobenxone and Octyl Methoxycinnamate (OMC). Making cocoa bean extract was extracted by maceration using 80% ethanol solvent, making sunscreen extract of cocoa bean extract made in three formulations with concentrations of 10%, 15% and 20%, evaluating cream preparations and determining SPF values (Sun Protection Factor). using UV-Vis spectrophotometry.The results of the study showed differences in SPF values between cocoa bean extract creams. The concentration that has the highest SPF value is 20% with an SPF value of 15.22. The SPF value obtained from each formula is in the maximum category, the recommended value is 15.00. The best SPF value is found at a concentration of 20%, which is 15.22.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85097122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction : Fish is a food that is easily damaged by enzymes or microorganism’s biological decay, thus requiring special handling. The process of spoilage of fish can be caused mainly by the activity of enzymes found in the body. This study aims to find out whether there are contaminants of Escherichia coli on mackerel (Rastrelliger sp) and dencis fish (Decapterus russelli) which are sold at the Deli Tua traditional market. Method : This type of research is true experimental with a Post Test Only Control Group Design. Sample was collected from the traditional market in Deli Tua with purposive sampling. Result : from the observation of the number of bacterial colonies on the PCA media with mackerel and dencis fish samples in accordance with SNI because it exceeds 5,0X105 CFU/g. Conclusion : From the results of the study note that there is the contamination of Escherichia coli bacteria in mackerel (Rastrelliger sp) and Dencis fish (Decapterus russelli) which are sold in the Deli Tua traditional market.
{"title":"IDENTIFIKASI CEMARAN BAKTERI (Escherichia coli) TERHADAP IKAN KEMBUNG DAN IKAN DENCIS YANG DIJUAL DI PASAR TRADISIONAL DELI TUA","authors":"Firdaus Fahdi, Dwi Pratiwi, Helviani Sari","doi":"10.36656/jpfh.v2i2.224","DOIUrl":"https://doi.org/10.36656/jpfh.v2i2.224","url":null,"abstract":"Introduction : Fish is a food that is easily damaged by enzymes or microorganism’s biological decay, thus requiring special handling. The process of spoilage of fish can be caused mainly by the activity of enzymes found in the body. This study aims to find out whether there are contaminants of Escherichia coli on mackerel (Rastrelliger sp) and dencis fish (Decapterus russelli) which are sold at the Deli Tua traditional market. Method : This type of research is true experimental with a Post Test Only Control Group Design. Sample was collected from the traditional market in Deli Tua with purposive sampling. Result : from the observation of the number of bacterial colonies on the PCA media with mackerel and dencis fish samples in accordance with SNI because it exceeds 5,0X105 CFU/g. Conclusion : From the results of the study note that there is the contamination of Escherichia coli bacteria in mackerel (Rastrelliger sp) and Dencis fish (Decapterus russelli) which are sold in the Deli Tua traditional market.","PeriodicalId":17717,"journal":{"name":"Jurnal Penelitian Farmasi & Herbal","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90525917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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