Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.520
K. Ishikawa, Takahiro Matsuo, Masumi Suzuki-Shimizu, Y. Uehara, Nobuyoshi Mori
St Luke's International Hospital had been accepting a large number of patients with mild to severe COVID-19, before COVID-19 became a designated infectious disease on February 1, 2020 The first patient with COVID-19 admitted to our hospital was a man in his 40s from Wuhan, the second case of COVID-19 registered in Japan, and officially, the first case in a person of Chinese origin in Japan The third patient, a Canadian man in his 60s who contracted the infection in the cruise ship, Diamond Princess, had very severe disease However, his clinical symptoms improved and he was discharged from the hospital In this paper, we discuss four cases of COVID-19
{"title":"Four Case Reports of Coronavirus Disease 2019 (COVID-19) in Two Wuhan-resident Chinese and Two Cruise Ship Passengers Admitted to Our Hospital","authors":"K. Ishikawa, Takahiro Matsuo, Masumi Suzuki-Shimizu, Y. Uehara, Nobuyoshi Mori","doi":"10.11150/KANSENSHOGAKUZASSHI.94.520","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.520","url":null,"abstract":"St Luke's International Hospital had been accepting a large number of patients with mild to severe COVID-19, before COVID-19 became a designated infectious disease on February 1, 2020 The first patient with COVID-19 admitted to our hospital was a man in his 40s from Wuhan, the second case of COVID-19 registered in Japan, and officially, the first case in a person of Chinese origin in Japan The third patient, a Canadian man in his 60s who contracted the infection in the cruise ship, Diamond Princess, had very severe disease However, his clinical symptoms improved and he was discharged from the hospital In this paper, we discuss four cases of COVID-19","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83624956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Patient with COVID-19 Pneumonia Who Developed Ventricular Fibrillation during Treatment with Hydroxychloroquine, Azithromycin and Favipiravir","authors":"Kazuhiro Oshima, Gaku Kuwahara, Waki Imoto, Kazushi Yamairi, Wataru Shibata, Koichi Yamada, Ayako Kiritoshi, Shinichiro Kaga, Tetsuro Nishimura, Y. Mizobata, H. Kakeya","doi":"10.11150/KANSENSHOGAKUZASSHI.94.600","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.600","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73778112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.568
Y. Miyazawa, K. Yanagisawa, Y. Ogawa, H. Koiso, Y. Tokue, H. Handa
As no specific therapeutic agents have been established yet for coronavirus disease 2019 (COVID-19), the illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), symptomatic therapy is the mainstay of treatment Although the “Concept of antiviral treatment for COVID-19, First edition” published by the Japanese Association for Infectious Diseases recommends the use of antiviral medication for infected individuals over the age of 50 years, we have documented the case of a 73-year-old woman with COVID-19 pneumonia who improved without antiviral medication The patient became infected with SARS-CoV-2 on the cruise ship, Diamond Princess, and first tested positive for SARS-CoV-2, by the RT-PCR test, on February 15, 2020 She was admitted to another hospital with fever and pneumonia on February 16, and on February, the pneumonia worsened in severity, she was transferred to our hospital However, her condition improved spontaneously within a few days, without any antiviral medication This report is very valuable for documenting the natural history of COVID-19 pneumonia and can be considered as a reference case for formulating strategies for antiviral drug administration for COVID-19 patients in the future
{"title":"COVID-19 Pneumonia in a Patient in Her Seventies that Improved without Antiviral Drug Treatment： A Case Study","authors":"Y. Miyazawa, K. Yanagisawa, Y. Ogawa, H. Koiso, Y. Tokue, H. Handa","doi":"10.11150/KANSENSHOGAKUZASSHI.94.568","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.568","url":null,"abstract":"As no specific therapeutic agents have been established yet for coronavirus disease 2019 (COVID-19), the illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), symptomatic therapy is the mainstay of treatment Although the “Concept of antiviral treatment for COVID-19, First edition” published by the Japanese Association for Infectious Diseases recommends the use of antiviral medication for infected individuals over the age of 50 years, we have documented the case of a 73-year-old woman with COVID-19 pneumonia who improved without antiviral medication The patient became infected with SARS-CoV-2 on the cruise ship, Diamond Princess, and first tested positive for SARS-CoV-2, by the RT-PCR test, on February 15, 2020 She was admitted to another hospital with fever and pneumonia on February 16, and on February, the pneumonia worsened in severity, she was transferred to our hospital However, her condition improved spontaneously within a few days, without any antiviral medication This report is very valuable for documenting the natural history of COVID-19 pneumonia and can be considered as a reference case for formulating strategies for antiviral drug administration for COVID-19 patients in the future","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74711467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.514
T. Tsuchida, Yukitaka Yamasaki, H. Kunishima, Masanori Hirose, S. Fujitani, T. Matsuda
On April 5, 2020, guidelines for COVID-19 were issued that allowed asymptomatic carriers and mildly ill persons to remain at home However, due to the unexpected increase in the number of symptomatic patients, many patients are now hospitalized We accepted COVID-19 patients from the cruise ship, Diamond Princess We focused on 6 cases with mild symptoms and evaluated the results of chest computed tomography (CT) and blood tests, the clinical course, the period until two consecutive negative test results of RT-PCR, and the length of hospitalization in these patients
{"title":"Clinical Course of Patients with a Positive Test Result for SARS-CoV-2： Presence or Absence of Pneumonia and the Time until a Negative Result of PCR in 6 Cases","authors":"T. Tsuchida, Yukitaka Yamasaki, H. Kunishima, Masanori Hirose, S. Fujitani, T. Matsuda","doi":"10.11150/KANSENSHOGAKUZASSHI.94.514","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.514","url":null,"abstract":"On April 5, 2020, guidelines for COVID-19 were issued that allowed asymptomatic carriers and mildly ill persons to remain at home However, due to the unexpected increase in the number of symptomatic patients, many patients are now hospitalized We accepted COVID-19 patients from the cruise ship, Diamond Princess We focused on 6 cases with mild symptoms and evaluated the results of chest computed tomography (CT) and blood tests, the clinical course, the period until two consecutive negative test results of RT-PCR, and the length of hospitalization in these patients","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80177713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.490
H. Shimizu, Yuki Ikeda, T. Imai, T. Osumi, K. Kasai, Hiroki Watanabe, M. Masuda, T. Takasaki, O. Akasaka, M. Nishikawa, Hideaki Anan, Y. Tokita
The outbreak of the novel coronavirus infection in Wuhan City, Hubei Province, China, in December 2019, has spread rapidly around the world, and the number of cases with no apparent route of transmission (cases of community transmission) is increasing in Japan We have encountered 45 cases of COVID-19 infection, including 33 male and 12 female patients The average age of the patients was 50 6 years The symptoms were fever in 39 (86 7%) cases, cough in 33 (73 3%) cases, malaise in 24 (53 3%) cases, and diarrhea in 5 (11 1%) cases In addition, according to the Kanagawa-model severity classification constructed by Kanagawa Prefecture to avoid collapse of the medical infrastructure caused by a sudden increase in patients, 30 cases were classified as having mild disease, 14 as having moderately severe disease, and 1 as having severe disease Of the 30 patients with mild disease, 1 (3 3%) showed deterioration to moderately severe disease during the clinical course, and of the 14 patients with moderately severe disease, 6 (42 9%) showed deterioration to severe disease The findings in respect of the subsequent clinical course of the patients suggest that the Kanagawa-model severity classification is a reasonable classification for satisfactory triage of patients
{"title":"Clinical Study of 45 Cases of COVID-19 and a Consideration of Severity Classification by the Kanagawa Model","authors":"H. Shimizu, Yuki Ikeda, T. Imai, T. Osumi, K. Kasai, Hiroki Watanabe, M. Masuda, T. Takasaki, O. Akasaka, M. Nishikawa, Hideaki Anan, Y. Tokita","doi":"10.11150/KANSENSHOGAKUZASSHI.94.490","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.490","url":null,"abstract":"The outbreak of the novel coronavirus infection in Wuhan City, Hubei Province, China, in December 2019, has spread rapidly around the world, and the number of cases with no apparent route of transmission (cases of community transmission) is increasing in Japan We have encountered 45 cases of COVID-19 infection, including 33 male and 12 female patients The average age of the patients was 50 6 years The symptoms were fever in 39 (86 7%) cases, cough in 33 (73 3%) cases, malaise in 24 (53 3%) cases, and diarrhea in 5 (11 1%) cases In addition, according to the Kanagawa-model severity classification constructed by Kanagawa Prefecture to avoid collapse of the medical infrastructure caused by a sudden increase in patients, 30 cases were classified as having mild disease, 14 as having moderately severe disease, and 1 as having severe disease Of the 30 patients with mild disease, 1 (3 3%) showed deterioration to moderately severe disease during the clinical course, and of the 14 patients with moderately severe disease, 6 (42 9%) showed deterioration to severe disease The findings in respect of the subsequent clinical course of the patients suggest that the Kanagawa-model severity classification is a reasonable classification for satisfactory triage of patients","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80312904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.535
Heita Kitajima, Yoshitaka Tamura, Shoji Hashimoto, Tsuyoshi Arai, T. Nagai
The disease outbreak caused by the novel coronavirus, SARS-CoV-2, in December 2020 in Wuhan, China, has spread worldwide, threatening global health While SARS-CoV-2 is now established as the cause of coronavirus disease 2019 (now named COVID-19), a respiratory illness, it has also become clear that some people with SARS-CoV-2 infection may exhibit no symptoms at all We report the clinical characteristics and course of three asymptomatic patients who contracted SARS-CoV-2 infection on the cruise ship, Diamond Princess The three patients did not have any symptoms at admission, however, all showed bilateral ground-glass opacities, predominantly distributed in the lung periphery, with occasional consolidation, on the plain chest radiograph All three showed a smooth clinical course, and remained asymptomatic throughout the course of the infection These cases serve to emphasize that patients without any symptoms could have COVID-19 pneumonia, and should be noted the possibility that mild cases and early onset of severe cases are included even in asymptomatic patients According to one published paper, chest CT may be useful for early detection of COVID-19 pneumonia In addition, other reports have documented the changes on chest CT associated with COVID-19 pneumonia from onset until recovery From our experience of these cases and the published reports mentioned above, we consider that CT may be useful for the diagnosis of COVID-19 and determining the timing of onset of the disease
{"title":"Three Asymptomatic Patients with SARS-CoV-2 Infection","authors":"Heita Kitajima, Yoshitaka Tamura, Shoji Hashimoto, Tsuyoshi Arai, T. Nagai","doi":"10.11150/KANSENSHOGAKUZASSHI.94.535","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.535","url":null,"abstract":"The disease outbreak caused by the novel coronavirus, SARS-CoV-2, in December 2020 in Wuhan, China, has spread worldwide, threatening global health While SARS-CoV-2 is now established as the cause of coronavirus disease 2019 (now named COVID-19), a respiratory illness, it has also become clear that some people with SARS-CoV-2 infection may exhibit no symptoms at all We report the clinical characteristics and course of three asymptomatic patients who contracted SARS-CoV-2 infection on the cruise ship, Diamond Princess The three patients did not have any symptoms at admission, however, all showed bilateral ground-glass opacities, predominantly distributed in the lung periphery, with occasional consolidation, on the plain chest radiograph All three showed a smooth clinical course, and remained asymptomatic throughout the course of the infection These cases serve to emphasize that patients without any symptoms could have COVID-19 pneumonia, and should be noted the possibility that mild cases and early onset of severe cases are included even in asymptomatic patients According to one published paper, chest CT may be useful for early detection of COVID-19 pneumonia In addition, other reports have documented the changes on chest CT associated with COVID-19 pneumonia from onset until recovery From our experience of these cases and the published reports mentioned above, we consider that CT may be useful for the diagnosis of COVID-19 and determining the timing of onset of the disease","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75512612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.563
Nobuaki Suzuki, Yoshitaka Shiratori, T. Yokoi, Takahiro Kimura, Shinji Takahashi, S. Nishide, Takashi Aoyagi, N. Hayami, N. Iso-o, T. Kohyama, Minoru Yoshida, K. Kikuchi, M. Hara
We report the case of an 85-year-old woman who was transported to our hospital by ambulance with progressively worsening dyspnea and hypoxia She had no history of contact with any patient with coronavirus disease 2019 (COVID-19) The peripheral arterial oxygen saturation level on a 10 L/min non-rebreather-type mask was as low as 80% Chest auscultation revealed coarse crackles After emergency intubation, it was surmised that the probability of heart failure was low because of the lack of pink, frothy sputum Bacterial pneumonia was also considered to be unlikely, as the sputum was not purulent Moreover, laboratory data revealed a normal white blood cell count (6,100/μL) and no elevation of the serum procalcitonin level (0 63 ng/mL), which were also consistent with the condition not likely to be a bacterial infection Pulmonary thromboembolism was ruled out by the presence of coarse crackles on chest auscultation and normal blood pressure Thereafter, the possibility of COVID-19 was considered and the patient was immediately isolated Two days later, the polymerase chain reaction test for COVID-19 returned positive There was no evidence of transmission of the virus to the healthcare personnel who had treated this patient, including the 6 with medium-risk exposure, during the 3-week period after the exposure In the COVID-19 pandemic era, rapid differential diagnosis of hypoxia is essential to prevent further transmission of SARS-CoV-2 infection Our case highlights the importance of the sputum appearance/characteristics and laboratory data for rapidly ruling out diseases other than COVID-19
{"title":"Rapid Diagnosis of COVID-19 in A Patient without A Positive History of Contact Who Presented with Severe Hypoxia：Case Report","authors":"Nobuaki Suzuki, Yoshitaka Shiratori, T. Yokoi, Takahiro Kimura, Shinji Takahashi, S. Nishide, Takashi Aoyagi, N. Hayami, N. Iso-o, T. Kohyama, Minoru Yoshida, K. Kikuchi, M. Hara","doi":"10.11150/KANSENSHOGAKUZASSHI.94.563","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.563","url":null,"abstract":"We report the case of an 85-year-old woman who was transported to our hospital by ambulance with progressively worsening dyspnea and hypoxia She had no history of contact with any patient with coronavirus disease 2019 (COVID-19) The peripheral arterial oxygen saturation level on a 10 L/min non-rebreather-type mask was as low as 80% Chest auscultation revealed coarse crackles After emergency intubation, it was surmised that the probability of heart failure was low because of the lack of pink, frothy sputum Bacterial pneumonia was also considered to be unlikely, as the sputum was not purulent Moreover, laboratory data revealed a normal white blood cell count (6,100/μL) and no elevation of the serum procalcitonin level (0 63 ng/mL), which were also consistent with the condition not likely to be a bacterial infection Pulmonary thromboembolism was ruled out by the presence of coarse crackles on chest auscultation and normal blood pressure Thereafter, the possibility of COVID-19 was considered and the patient was immediately isolated Two days later, the polymerase chain reaction test for COVID-19 returned positive There was no evidence of transmission of the virus to the healthcare personnel who had treated this patient, including the 6 with medium-risk exposure, during the 3-week period after the exposure In the COVID-19 pandemic era, rapid differential diagnosis of hypoxia is essential to prevent further transmission of SARS-CoV-2 infection Our case highlights the importance of the sputum appearance/characteristics and laboratory data for rapidly ruling out diseases other than COVID-19","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76119705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.587
M. Miyajima, K. Nakaharai, T. Hoshina, Y. Nakazawa, Yukie Mishima, K. Sawaki, Y. Sakamoto, Kwang-Gyun Lee, Y. Hosaka, T. Horino, Masaki Yoshida, S. Hori
{"title":"A Report on Changes in The Viral Load in Pharyngeal and Nasopharyngeal Swab Specimens in A Patient with Community-acquired Coronavirus Infection 2019 (COVID-19)","authors":"M. Miyajima, K. Nakaharai, T. Hoshina, Y. Nakazawa, Yukie Mishima, K. Sawaki, Y. Sakamoto, Kwang-Gyun Lee, Y. Hosaka, T. Horino, Masaki Yoshida, S. Hori","doi":"10.11150/KANSENSHOGAKUZASSHI.94.587","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.587","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81615099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.608
Hidenori Takahashi, Y. Iwasaki, T. Yokozawa, N. Ichinose, T. Oda
{"title":"A Case of COVID-19 Pneumonia without Respiratory Symptoms, Referred for “suspected pyogenic spondylitis”","authors":"Hidenori Takahashi, Y. Iwasaki, T. Yokozawa, N. Ichinose, T. Oda","doi":"10.11150/KANSENSHOGAKUZASSHI.94.608","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.608","url":null,"abstract":"","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89143374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-07-20DOI: 10.11150/KANSENSHOGAKUZASSHI.94.553
K. Takada, J. Takatsuka, Chihiro Onagi, Kimi Yoshida, Kazuo Ueda, N. Tokura, Taro Nakano, T. Kinoshita, A. Oki, T. Fujii, A. Ebihara
Our hospital was introduced in the media as the hospital at which the first patient who died of COVID-19 infection in Japan was hospitalized Patients with pneumonia associated with COVID-19 sometimes show rapid deterioration of the respiratory status, with a poor prognosis The cases encountered by us that we report here also needed intensive long-term respiratory management ARDS is an important pathological condition complicating COVID-19 pneumonia From the perspective of the continuing pathology of ARDS, we treated the patients with a steroid and sivelestat However, it became clear that the respiratory pathology in the patients could not be adequately addressed by the uniform treatment protocol for ARDS In conclusion, inpatient treatment in a local community-based small hospital without an ICU can be extremely difficult
{"title":"Report on the Difficulty in Infection Control and Treatment of Patients with Severe COVID-19 Pneumonia Who Required Assisted Ventilation and Ventilator Management at a Local Community-based Hospital in Japan","authors":"K. Takada, J. Takatsuka, Chihiro Onagi, Kimi Yoshida, Kazuo Ueda, N. Tokura, Taro Nakano, T. Kinoshita, A. Oki, T. Fujii, A. Ebihara","doi":"10.11150/KANSENSHOGAKUZASSHI.94.553","DOIUrl":"https://doi.org/10.11150/KANSENSHOGAKUZASSHI.94.553","url":null,"abstract":"Our hospital was introduced in the media as the hospital at which the first patient who died of COVID-19 infection in Japan was hospitalized Patients with pneumonia associated with COVID-19 sometimes show rapid deterioration of the respiratory status, with a poor prognosis The cases encountered by us that we report here also needed intensive long-term respiratory management ARDS is an important pathological condition complicating COVID-19 pneumonia From the perspective of the continuing pathology of ARDS, we treated the patients with a steroid and sivelestat However, it became clear that the respiratory pathology in the patients could not be adequately addressed by the uniform treatment protocol for ARDS In conclusion, inpatient treatment in a local community-based small hospital without an ICU can be extremely difficult","PeriodicalId":17724,"journal":{"name":"Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91084656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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