Haniyeh Yousefzadeh, R. Fathi, Ellahe Talebi Gorkani, A. Hosseini
Background and Objectives Omentin-1 is a new adipokine with a potential to increase insulin sensitivity, and is associated with lipid profile. There are limited studies on the effect of exercise on the serum level of Omentin-1. The present study aims to investigate the effect of progressive resistance training (PRT) on plasma level of omentin-1 and glycemic control in diabetic male rats. Subjects and Methods In this study, 24 male Wistar rats were randomly divided into three groups: Control, diabetic, and diabetic+PRT. The training group performed a PRT program using a ladder (three days a week, for 4 weeks). Body weight, glucose level, amentin-1 level, insulin level, and lipid profile were measured. Results The PRT significantly increased plasma levels of omentin-1 and triglycerides in the diabetic + PRT group compared to the diabetic group (P=0.017). There was no significant difference in high-density lipoprotein (F=0.318, P>0.05), low-density lipoprotein (F=0.612, P>0.05) and cholesterol (F=0.049, P>0.05) levels between the study groups. Conclusion The PRT improves omentin-1 and insulin resistance in diabetic rats.
{"title":"Effect of 4 Weeks of Progressive Resistance Training on Plasma Levels of Omentin-1 and Metabolic Factors in Diabetic Male Rats","authors":"Haniyeh Yousefzadeh, R. Fathi, Ellahe Talebi Gorkani, A. Hosseini","doi":"10.32598/jsmj.21.2.2507","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2507","url":null,"abstract":"Background and Objectives Omentin-1 is a new adipokine with a potential to increase insulin sensitivity, and is associated with lipid profile. There are limited studies on the effect of exercise on the serum level of Omentin-1. The present study aims to investigate the effect of progressive resistance training (PRT) on plasma level of omentin-1 and glycemic control in diabetic male rats. Subjects and Methods In this study, 24 male Wistar rats were randomly divided into three groups: Control, diabetic, and diabetic+PRT. The training group performed a PRT program using a ladder (three days a week, for 4 weeks). Body weight, glucose level, amentin-1 level, insulin level, and lipid profile were measured. Results The PRT significantly increased plasma levels of omentin-1 and triglycerides in the diabetic + PRT group compared to the diabetic group (P=0.017). There was no significant difference in high-density lipoprotein (F=0.318, P>0.05), low-density lipoprotein (F=0.612, P>0.05) and cholesterol (F=0.049, P>0.05) levels between the study groups. Conclusion The PRT improves omentin-1 and insulin resistance in diabetic rats.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88763940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Banin Azrnoush, Zinat Nikaeen, Farideh Ashraf Ganjouei, Zahra Haji Anzahaei
Background and Objectives Physical activity is one of the main lifestyle variables related to health. This study aims to investigate the effectiveness of an educational program based on the theory of planned behavior (TPB) in improving the attitude and intention of male adolescents regarding physical activity. Subjects and Methods In the present study, 40 male high school students were divided into two groups of intervention (n=20) and control (n=20). The educational package was designed and provided to them at 10 sessions. Two 18-item TPB-based questionnaires related to attitude towards physical activity and intention to participate in sports activities were used. Results The educational program explained 0.238% of changes in attitudes, 0.189% of changes in knowledge, 0.247% of changes in subjective norms, 0.071% of changes in perceived behavioral control, 0.261% of changes in behavioral intentions. In total, it explained 0.458% of changes in intention to participate in/attitude towards sports activities. The educational program explained 0.609% of changes in attitude, 0.363% of changes in knowledge, 0.017% of changes in perceived behavioral control, and 0.015% of changes in behavioral intention. In total, it explained 0.731% of changes in students’ intention to participate in/attitude towards sports events. Conclusion The TPB-based educational program is effective in promoting high school students’ attitude towards physical activity and their intention to participate in sports events and thus improve their health.
{"title":"Modifying the Pattern of Tendency to Health-related Behaviors in Adolescent Boys","authors":"Banin Azrnoush, Zinat Nikaeen, Farideh Ashraf Ganjouei, Zahra Haji Anzahaei","doi":"10.32598/jsmj.21.2.2817","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2817","url":null,"abstract":"Background and Objectives Physical activity is one of the main lifestyle variables related to health. This study aims to investigate the effectiveness of an educational program based on the theory of planned behavior (TPB) in improving the attitude and intention of male adolescents regarding physical activity. Subjects and Methods In the present study, 40 male high school students were divided into two groups of intervention (n=20) and control (n=20). The educational package was designed and provided to them at 10 sessions. Two 18-item TPB-based questionnaires related to attitude towards physical activity and intention to participate in sports activities were used. Results The educational program explained 0.238% of changes in attitudes, 0.189% of changes in knowledge, 0.247% of changes in subjective norms, 0.071% of changes in perceived behavioral control, 0.261% of changes in behavioral intentions. In total, it explained 0.458% of changes in intention to participate in/attitude towards sports activities. The educational program explained 0.609% of changes in attitude, 0.363% of changes in knowledge, 0.017% of changes in perceived behavioral control, and 0.015% of changes in behavioral intention. In total, it explained 0.731% of changes in students’ intention to participate in/attitude towards sports events. Conclusion The TPB-based educational program is effective in promoting high school students’ attitude towards physical activity and their intention to participate in sports events and thus improve their health.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90276166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Hashemibeni, M. Izadi, A. Valiani, E. Esfandiari, H. Bahramian, M. Pourentezari
Background and Objectives Cartilage tissue engineering, by using stem cells, scaffolding and appropriate growth factors, seek to produce natural cartilage tissue to replace damaged tissue and solve the problems that exist in the treatment of cartilage damage. This study aims to compare chondrogenic differentiation of adipose-derived stem cells under the influence of the transforming growth factor beta 3 (TGF-β3), Kartogenin, and avocado/soybean unsaponifiables (ASU) on the fibrin scaffold in the laboratory and animal models. Subjects and Methods In this experimental laboratory study, after extraction of stem cells from human adipose tissue, induction of chondrogenic differentiation was done for 14 days on the fibrin scaffold in laboratory. The cells differentiated in the fibrin scaffold were transplanted subcutaneously under the skin of male rats for two weeks. Then, comparison of histological and immunohistochemical studies was performed in both laboratory and animal models. Results A significant increase in the density of Toluidine blue dye accumulation was observed in TGF-β3, Kartogenin and ASU groups in the animal model compared to the laboratory model. Immunohistochemical results for the collagen type X accumulation in the TGF-β3 group showed a significant increase in the animal model compared to the laboratory model. In the Kartogenin and ASU groups, the accumulation of collagen type Χ showed a significant decrease in the animal model compared to the laboratory model. Conclusion The implantation of differentiated cartilage cells in laboratory before subcutaneous transfer to the skin can help mature and complete the characteristics of the constructed cartilage.
{"title":"Comparison of Chondrogenesis Induction by TGF-β3, Kartogenin and Avocado/ soybean Unsaponifiables Between Laboratory and Animal Models","authors":"B. Hashemibeni, M. Izadi, A. Valiani, E. Esfandiari, H. Bahramian, M. Pourentezari","doi":"10.32598/jsmj.21.2.2296","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2296","url":null,"abstract":"Background and Objectives Cartilage tissue engineering, by using stem cells, scaffolding and appropriate growth factors, seek to produce natural cartilage tissue to replace damaged tissue and solve the problems that exist in the treatment of cartilage damage. This study aims to compare chondrogenic differentiation of adipose-derived stem cells under the influence of the transforming growth factor beta 3 (TGF-β3), Kartogenin, and avocado/soybean unsaponifiables (ASU) on the fibrin scaffold in the laboratory and animal models. Subjects and Methods In this experimental laboratory study, after extraction of stem cells from human adipose tissue, induction of chondrogenic differentiation was done for 14 days on the fibrin scaffold in laboratory. The cells differentiated in the fibrin scaffold were transplanted subcutaneously under the skin of male rats for two weeks. Then, comparison of histological and immunohistochemical studies was performed in both laboratory and animal models. Results A significant increase in the density of Toluidine blue dye accumulation was observed in TGF-β3, Kartogenin and ASU groups in the animal model compared to the laboratory model. Immunohistochemical results for the collagen type X accumulation in the TGF-β3 group showed a significant increase in the animal model compared to the laboratory model. In the Kartogenin and ASU groups, the accumulation of collagen type Χ showed a significant decrease in the animal model compared to the laboratory model. Conclusion The implantation of differentiated cartilage cells in laboratory before subcutaneous transfer to the skin can help mature and complete the characteristics of the constructed cartilage.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"8 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75497989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objectives Motor competence (MC) in fundamental motor skills (FMS) is needed for children to participate in physical activities. This study aims to investigate the relationship between body mass index (BMI) and MC in children aged 7-10 years. Subjects and Methods This is a correlational study with a cross-sectional design. Participants were 828 children aged 7-10 years in Ahvaz, Iran who were selected by cluster random sampling method. The test of gross motor development-3, a digital scale, and a stadimeter were used to collect data. Descriptive statistics, Pearson correlation test, and two-way analysis of variance were used in data analysis. Results The prevalence of overweight and obesity in children was high. There was a significant negative relationship between BMI and MC in locomotor skills and in total FMS (P<0.05), but no significant relationship was observed between BMI and MC in ball skills (P>0.05). The effect of age was significant on the MC in both locomotor and ball skills and in total FMS (P<0.05). The effect of gender was not significant on the MC in locomotor skills (P>0.05), but was significant on the MC in ball skills and in total FMS (P<0.05). Conclusion Children’s BMI is associated with their low MC in FMS. The increase of MC in FMS with the increase of age confirms the developmental nature of FMS. Due to the lower MC of girls in ball skills, they are at higher risk of delayed motor development. It is recommended to improve their delayed motor development and MC in ball skills by developing appropriate interventions.
{"title":"Relationship Between Body Mass Index and Motor Competence in Children Aged 7-10 Years: A Cross-sectional Study","authors":"Farzad Mohammadi","doi":"10.32598/jsmj.21.2.2641","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2641","url":null,"abstract":"Background and Objectives Motor competence (MC) in fundamental motor skills (FMS) is needed for children to participate in physical activities. This study aims to investigate the relationship between body mass index (BMI) and MC in children aged 7-10 years. Subjects and Methods This is a correlational study with a cross-sectional design. Participants were 828 children aged 7-10 years in Ahvaz, Iran who were selected by cluster random sampling method. The test of gross motor development-3, a digital scale, and a stadimeter were used to collect data. Descriptive statistics, Pearson correlation test, and two-way analysis of variance were used in data analysis. Results The prevalence of overweight and obesity in children was high. There was a significant negative relationship between BMI and MC in locomotor skills and in total FMS (P<0.05), but no significant relationship was observed between BMI and MC in ball skills (P>0.05). The effect of age was significant on the MC in both locomotor and ball skills and in total FMS (P<0.05). The effect of gender was not significant on the MC in locomotor skills (P>0.05), but was significant on the MC in ball skills and in total FMS (P<0.05). Conclusion Children’s BMI is associated with their low MC in FMS. The increase of MC in FMS with the increase of age confirms the developmental nature of FMS. Due to the lower MC of girls in ball skills, they are at higher risk of delayed motor development. It is recommended to improve their delayed motor development and MC in ball skills by developing appropriate interventions.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76992567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melika Khoshbin, S. Naghibi, Mohammad ShariatzadehJoneydi, Maryam Vatandoost, A. Zare Banaadkouki
Background and Objectives This study aims to evaluate the effect of different intensities of aerobic training on the expression of transcription factor 4 (TCF4) and C/EBP homologous protein (CHOP10) genes in subcutaneous adipose tissue of male Wistar rats. Subjects and Methods In this experimental study, 32 male Wistar rats with a mean age of 6 weeks and a weight of 237±33 gr were used. Then, they were randomly divided into four groups of 8, including control group, moderate-intensity aerobic training (MIT), high-intensity aerobic training (HIT), and highintensity interval aerobic training (HIIT). The MIT group trained at an intensity of 65% VO2max for 47 minutes. The HIT group running at a speed of 20 meters per minute with an increasing inclination for 40 minutes. The HIIT group trained at an intensity of 90-100% VO2max for 37 minutes. Adipose tissue sample was collected 24 hours after the last training session to evaluate the expression of TCF4 and CHOP10 genes by real-time PCR method. Results There was a significant difference in the expression of CHOP10 gene in the subcutaneous tissue of male Wistar rats in the HIIT group compared to the MIT and control group (P=0.004). However, no significant difference was observed between HIIT and HIT groups (P=1). In addition, there was a significant difference in TCF4 gene expression in the HIIT group compared to the control group (P=0.006). However, no significant difference was observed between HIIT and HIT groups (P=1) Conclusion The expression level of adipogenic genes decreased after HIIT. These findings indicate that this exercise is effective in controlling the expression of genes involved in fat metabolism.
{"title":"The Effect of 8 Weeks of High Intensity Training vs High Volume Training on TCF4/CHOP10 Gene Complexes of Subcutaneous Fat Tissue in Male Rats","authors":"Melika Khoshbin, S. Naghibi, Mohammad ShariatzadehJoneydi, Maryam Vatandoost, A. Zare Banaadkouki","doi":"10.32598/jsmj.21.2.2552","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2552","url":null,"abstract":"Background and Objectives This study aims to evaluate the effect of different intensities of aerobic training on the expression of transcription factor 4 (TCF4) and C/EBP homologous protein (CHOP10) genes in subcutaneous adipose tissue of male Wistar rats. Subjects and Methods In this experimental study, 32 male Wistar rats with a mean age of 6 weeks and a weight of 237±33 gr were used. Then, they were randomly divided into four groups of 8, including control group, moderate-intensity aerobic training (MIT), high-intensity aerobic training (HIT), and highintensity interval aerobic training (HIIT). The MIT group trained at an intensity of 65% VO2max for 47 minutes. The HIT group running at a speed of 20 meters per minute with an increasing inclination for 40 minutes. The HIIT group trained at an intensity of 90-100% VO2max for 37 minutes. Adipose tissue sample was collected 24 hours after the last training session to evaluate the expression of TCF4 and CHOP10 genes by real-time PCR method. Results There was a significant difference in the expression of CHOP10 gene in the subcutaneous tissue of male Wistar rats in the HIIT group compared to the MIT and control group (P=0.004). However, no significant difference was observed between HIIT and HIT groups (P=1). In addition, there was a significant difference in TCF4 gene expression in the HIIT group compared to the control group (P=0.006). However, no significant difference was observed between HIIT and HIT groups (P=1) Conclusion The expression level of adipogenic genes decreased after HIIT. These findings indicate that this exercise is effective in controlling the expression of genes involved in fat metabolism.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"45 2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90279991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objectives This study aims to assess changes in anterior chamber parameters after prophylactic laser peripheral iridotomy (LPI) in patients with primary angle-closure suspect (PACS). Subjects and Methods In this study, 43 patients (86 eyes) with PACS (Mean age: 55.16±9.14 years) participated. The anterior chamber parameters including anterior chamber volume (ACV), anterior chamber angle (ACA) and central anterior chamber depth (CACD) were extracted from the Pentacam map at 0-180° meridian before and one month after prophylactic LPI. Results The only parameter that had a significant increase after LPI was ACV, which increased from 99.26±19.57 mm3 to 113.09±19.712 mm3 after LPI (P<0.001). The relationship between age and ACV changes after LPI was statistically significant (P=0.014), indicating that the increase of age is associated with the increased of ACV after LPI. The relationship of ACV and ACD with their initial values was statistically significant, such that with the increase of the initial values of ACV and ACD, their changes decrease. Due to the lack of significant increase in CACD after LPI, the relationship between its changes after LPI and its initial value cannot be relied upon. Conclusion ACV is the only anterior chamber parameter that changes significantly after prophylactic LPI. This parameter can be used as a measurable scale to evaluate and monitor the eyes of patients with PACS. Among the PACS cases, older patients and patients with lower initial ACV have greater increase of ACV after LPI
{"title":"Changes in Anterior Chamber Volume, Depth and Angle After Prophylactic Laser Peripheral Iridotomy in Patients With Primary Angle-closure Suspect","authors":"Fereydoun Farrahi, F. Ostadian, Rooyan Farrahi","doi":"10.32598/jsmj.21.2.2390","DOIUrl":"https://doi.org/10.32598/jsmj.21.2.2390","url":null,"abstract":"Background and Objectives This study aims to assess changes in anterior chamber parameters after prophylactic laser peripheral iridotomy (LPI) in patients with primary angle-closure suspect (PACS). Subjects and Methods In this study, 43 patients (86 eyes) with PACS (Mean age: 55.16±9.14 years) participated. The anterior chamber parameters including anterior chamber volume (ACV), anterior chamber angle (ACA) and central anterior chamber depth (CACD) were extracted from the Pentacam map at 0-180° meridian before and one month after prophylactic LPI. Results The only parameter that had a significant increase after LPI was ACV, which increased from 99.26±19.57 mm3 to 113.09±19.712 mm3 after LPI (P<0.001). The relationship between age and ACV changes after LPI was statistically significant (P=0.014), indicating that the increase of age is associated with the increased of ACV after LPI. The relationship of ACV and ACD with their initial values was statistically significant, such that with the increase of the initial values of ACV and ACD, their changes decrease. Due to the lack of significant increase in CACD after LPI, the relationship between its changes after LPI and its initial value cannot be relied upon. Conclusion ACV is the only anterior chamber parameter that changes significantly after prophylactic LPI. This parameter can be used as a measurable scale to evaluate and monitor the eyes of patients with PACS. Among the PACS cases, older patients and patients with lower initial ACV have greater increase of ACV after LPI","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72784269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Mohtasham, Amanollah Zarei Ahmadi, Mohsen Alisamir, N. S. Maram, A. Larki
Background and Objectives Antihistamine drugs for acute upper respiratory tract infection treatment in children have many side effects. In this study, a anti-cough syrup was prepared from Cordia (Sepestan in Persian) extract and its effect was compared to that of diphenhydramine syrup on cough relief of children with upper respiratory tract infection. Subjects and Methods This double-blind randomized clinical trial was conducted on 124 children with upper respiratory tract infection aged 6-12 years referred to Abouzar Hospital in Ahvaz, Iran during 2019- 2021 in two treatment groups. The first group was given Sepestan syrup at a dose of 20 mg/kg/day and the second group received diphenhydramine syrup at a dose of 5 mg/kg/day in four dosages. For three days, the number and severity of day-time and night-time coughs were examined and the data were analyzed with independent t-test and chi-square test in SPSS software, version 24. Results The number and severity of day-time and night-time coughs in the group received Sepestan syrup significantly decreased compared to the diphenhydramine group, without any side effects (P<0.001). Conclusion High polysaccharides, strong antioxidants, and anti-inflammatory compounds of Sepestan can reduce throat irritation and soften the chest. The mucilage in the Sepestan extract can dissolve in water and produce a viscous substance such as gelatin that cause softening of the breast and expectoration.
{"title":"Preparation of Sepestan Anti-cough Syrup and Comparison of its Effectiveness With Diphenhydramine Syrup in Treating Cough in Children With Upper Respiratory Tract Infection: A Double-blind Randomized Clinical Trial","authors":"N. Mohtasham, Amanollah Zarei Ahmadi, Mohsen Alisamir, N. S. Maram, A. Larki","doi":"10.32598/jsmj.21.4.2923","DOIUrl":"https://doi.org/10.32598/jsmj.21.4.2923","url":null,"abstract":"Background and Objectives Antihistamine drugs for acute upper respiratory tract infection treatment in children have many side effects. In this study, a anti-cough syrup was prepared from Cordia (Sepestan in Persian) extract and its effect was compared to that of diphenhydramine syrup on cough relief of children with upper respiratory tract infection. Subjects and Methods This double-blind randomized clinical trial was conducted on 124 children with upper respiratory tract infection aged 6-12 years referred to Abouzar Hospital in Ahvaz, Iran during 2019- 2021 in two treatment groups. The first group was given Sepestan syrup at a dose of 20 mg/kg/day and the second group received diphenhydramine syrup at a dose of 5 mg/kg/day in four dosages. For three days, the number and severity of day-time and night-time coughs were examined and the data were analyzed with independent t-test and chi-square test in SPSS software, version 24. Results The number and severity of day-time and night-time coughs in the group received Sepestan syrup significantly decreased compared to the diphenhydramine group, without any side effects (P<0.001). Conclusion High polysaccharides, strong antioxidants, and anti-inflammatory compounds of Sepestan can reduce throat irritation and soften the chest. The mucilage in the Sepestan extract can dissolve in water and produce a viscous substance such as gelatin that cause softening of the breast and expectoration.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90501645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marjan Mansouridara, Niloofar Rajai GhasemGheshlagi, Faezeh Heydari, F. Ghazalian, S. Ebrahimi, Roshan Askari, Farjam Rashedi
Background and Objectives Obesity is one of the most important concerns and problems that threaten health all over the world, and sports activity and healthy diet are the most important ways to treat and prevent it. so, this study aims to evaluate the effect of 12 weeks of high-intensity interval training (HIIT) and Ellagic Acid (EA) supplementation on oxidative/antioxidant markers in obese women. Subjects and Methods In this randomized clinical trial, 56 inactive obese women were randomly divided into four groups of HIIT, EA, EA+HIIT, and Control. The HIIT groups performed the training for 12 weeks including four 4-minute interval running at 85-95% HRpeak, 3 minutes of running at 50-60% HRpeak and 7 minutes of rest interval. EA supplement was administered at a dose of 50 mg/day for 12 weeks. Blood samples were collected from the subjects before and 48 hours after the last session to assess serum levels of glutathione peroxidase (GPx), Malondialdehyde (MDA), and total antioxidant capacity (TAC). Results There was a significant difference between EA+HIIT and HIIT groups in MDA (P=0.005), TAC (P=0.003) and GPx (P=0.0001) after intervention. There was a significant difference between the MDA and TAC values of the subjects in the studied groups after 12 weeks of HIIT with EA supplementation (P=0.0001). And this was the difference between the combined group (EA+HIIT) and other groups. Conclusion Twelve weeks of HIIT and EA supplementation can significantly improve antioxidant and oxidant factors in obese women.
{"title":"Randomized Double-blind Clinical Trial Examining the High Intensity Interval Training and Ellagic Acid Effects on Antioxidant, and Oxidative Stress Factors in 0bese Women","authors":"Marjan Mansouridara, Niloofar Rajai GhasemGheshlagi, Faezeh Heydari, F. Ghazalian, S. Ebrahimi, Roshan Askari, Farjam Rashedi","doi":"10.32598/jsmj.21.4.2515","DOIUrl":"https://doi.org/10.32598/jsmj.21.4.2515","url":null,"abstract":"Background and Objectives Obesity is one of the most important concerns and problems that threaten health all over the world, and sports activity and healthy diet are the most important ways to treat and prevent it. so, this study aims to evaluate the effect of 12 weeks of high-intensity interval training (HIIT) and Ellagic Acid (EA) supplementation on oxidative/antioxidant markers in obese women. Subjects and Methods In this randomized clinical trial, 56 inactive obese women were randomly divided into four groups of HIIT, EA, EA+HIIT, and Control. The HIIT groups performed the training for 12 weeks including four 4-minute interval running at 85-95% HRpeak, 3 minutes of running at 50-60% HRpeak and 7 minutes of rest interval. EA supplement was administered at a dose of 50 mg/day for 12 weeks. Blood samples were collected from the subjects before and 48 hours after the last session to assess serum levels of glutathione peroxidase (GPx), Malondialdehyde (MDA), and total antioxidant capacity (TAC). Results There was a significant difference between EA+HIIT and HIIT groups in MDA (P=0.005), TAC (P=0.003) and GPx (P=0.0001) after intervention. There was a significant difference between the MDA and TAC values of the subjects in the studied groups after 12 weeks of HIIT with EA supplementation (P=0.0001). And this was the difference between the combined group (EA+HIIT) and other groups. Conclusion Twelve weeks of HIIT and EA supplementation can significantly improve antioxidant and oxidant factors in obese women.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73872223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Yazdizadeh, Ali Habibi Kia, Pouya Kavianpour, Parnian Alavinejad
Background and Objectives The digital radiography offers a variety of image processing techniques. Due to the importance of the accuracy of this method and its widespread applications, in this study we aim to investigate the diagnose of vertical root fracture (VRF) by conventional digital radiography with and without unsharp masking (UM) filter. Subjects and Methods Radiographs were taken from 24 extracted anterior teeth before and after VRF induction. The root canal was prepared with passive step-back technique, and then the teeth were divided into two halves buccolingually with a very thin disk. The two halves were re-attached to each other and mounted in a mixture of gypsum and sawdust. After processing by the UM filter, the radiographs were evaluated by two observers to detect the presence or absence of VRF. Results For the first observer, the sensitivity of both methods was the same, while the specificity of the UM filtering mode was higher. For the second observer, the sensitivity of the unfiltered mode was higher, while the specificity of the two methods was the same. Conclusion There is no significant difference between digital radiography with and without the UM filter in diagnosing VRF. Due to the high sensivity and specifity of the UM filtering method, the specialist can use this filter based on personal preferences.
{"title":"Diagnosis of Vertical Root Fracture by Digital Radiography With and Without Unsharp Masking Filter: An In-vitro Study","authors":"M. Yazdizadeh, Ali Habibi Kia, Pouya Kavianpour, Parnian Alavinejad","doi":"10.32598/jsmj.21.4.2692","DOIUrl":"https://doi.org/10.32598/jsmj.21.4.2692","url":null,"abstract":"Background and Objectives The digital radiography offers a variety of image processing techniques. Due to the importance of the accuracy of this method and its widespread applications, in this study we aim to investigate the diagnose of vertical root fracture (VRF) by conventional digital radiography with and without unsharp masking (UM) filter. Subjects and Methods Radiographs were taken from 24 extracted anterior teeth before and after VRF induction. The root canal was prepared with passive step-back technique, and then the teeth were divided into two halves buccolingually with a very thin disk. The two halves were re-attached to each other and mounted in a mixture of gypsum and sawdust. After processing by the UM filter, the radiographs were evaluated by two observers to detect the presence or absence of VRF. Results For the first observer, the sensitivity of both methods was the same, while the specificity of the UM filtering mode was higher. For the second observer, the sensitivity of the unfiltered mode was higher, while the specificity of the two methods was the same. Conclusion There is no significant difference between digital radiography with and without the UM filter in diagnosing VRF. Due to the high sensivity and specifity of the UM filtering method, the specialist can use this filter based on personal preferences.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87025767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and Objectives Hypochondriasis (Illness anxiety disorder) is one of somatic disorders where a person has a fear of having a serious disease for at least 6 months, despite having physical health. Its prevalence is higher in people aged 20-30 years. This study aims to determine the prevalence of hypochondriasis and its related factors during the COVID-19 pandemic in medical students of Mazandaran University of Medical Sciences (MUMS) Subjects and Methods This descriptive study with a cross-sectional design was conducted in 2021. The study population consists of all students of MUMS. Of these, 125 students participated in the study, including 75 females (60%) and 50 males (40%) aged 19-27 years (mean age=22.80±2.54 years). The data collection tool was a questionnaire adapted from a hypochondriasis awareness questionnaire developed by Evans in 1980. The collected data were analyzed in SPSS software, version 26. Results It was found that 36.8% had no hypochondriasis, 28% were at risk of hypochondriasis, 18.2% had mild hypochondriasis, 13.6% had moderate hypochondriasis, and 3.2% had severe hypochondriasis. The relationship between age and hypochondriasis was statistically significant (P=0.025). Conclusion Due to the COVID-19 pandemic and being in quarantine, most of the MUMS students has hypochondriasis, where older students have higher level of hypochondriasis.
{"title":"Prevalence of Self-morbidity and Its Related Factors in COVID-19 Pandemic Conditions in Mazandaran Medical Students in 2021","authors":"Reza Salehinia, Reza Pourmohammad, Ebrahim Nasiri Formi","doi":"10.32598/jsmj.21.4.2571","DOIUrl":"https://doi.org/10.32598/jsmj.21.4.2571","url":null,"abstract":"Background and Objectives Hypochondriasis (Illness anxiety disorder) is one of somatic disorders where a person has a fear of having a serious disease for at least 6 months, despite having physical health. Its prevalence is higher in people aged 20-30 years. This study aims to determine the prevalence of hypochondriasis and its related factors during the COVID-19 pandemic in medical students of Mazandaran University of Medical Sciences (MUMS) Subjects and Methods This descriptive study with a cross-sectional design was conducted in 2021. The study population consists of all students of MUMS. Of these, 125 students participated in the study, including 75 females (60%) and 50 males (40%) aged 19-27 years (mean age=22.80±2.54 years). The data collection tool was a questionnaire adapted from a hypochondriasis awareness questionnaire developed by Evans in 1980. The collected data were analyzed in SPSS software, version 26. Results It was found that 36.8% had no hypochondriasis, 28% were at risk of hypochondriasis, 18.2% had mild hypochondriasis, 13.6% had moderate hypochondriasis, and 3.2% had severe hypochondriasis. The relationship between age and hypochondriasis was statistically significant (P=0.025). Conclusion Due to the COVID-19 pandemic and being in quarantine, most of the MUMS students has hypochondriasis, where older students have higher level of hypochondriasis.","PeriodicalId":17808,"journal":{"name":"Jundishapur Journal of Medical Sciences","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80588475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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