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The impact of the Breast Screen NSW transition from film to digital mammography, 2002–2016: a linked population health data analysis 2002-2016年新南威尔士州乳房筛查从胶片乳房x光检查到数字乳房x光检查的影响:相关人口健康数据分析。
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-17 DOI: 10.5694/mja2.70107
Rachel Farber, Nehmat Houssami, Katy J L Bell
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引用次数: 0
Defining “cure” for the asthmas 定义哮喘的“治愈”
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70088
Dennis Thomas, Vanessa M McDonald, Peter G Gibson, Richard Y Kim
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引用次数: 0
Who gets asthma, and why? 谁会得哮喘,为什么?
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70085
Denby J Evans, Peter D Sly, Paul Foster, Chantal Donovan
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引用次数: 0
Evidence from Australian cohort studies about asthma trajectories and transitions across the life course: a narrative review 来自澳大利亚队列研究的哮喘轨迹和生命历程过渡的证据:叙述性回顾
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70086
Caroline Lodge, Xin Dai, Ingrid A. Laing, Michael P Menden, Anthony Flynn, Gary P Anderson, Sarath Ranganathan, Shyamali C Dharmage

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引用次数: 0
Technological advances in the search for a CURE for asthma 寻找治疗哮喘方法的技术进步
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70084
Sara Quon, Timothy M Johanson, Ridhima Wadhwa, Alen Faiz, Anthony Flynn, Gary P Anderson, Amanda J Cox, Nicholas P West, Michael P Menden, Rhys S Allan

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引用次数: 0
Finding cures for asthma: new paradigms for drug discovery and therapy 寻找治疗哮喘的方法:药物发现和治疗的新范例
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70089
Aowen Zhuang, Dennis Thomas, Caroline Lodge, Jane E Bourke, John W Upham, Vanessa M McDonald, Peter AB Wark, Gary P Anderson
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引用次数: 0
Widening the lens of the social and commercial determinants of health 扩大健康的社会和商业决定因素的视野
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70100
Elizabeth Zuccala

Alcohol, tobacco, ultra-processed foods and sugar-sweetened beverages — these are the types of harmful products that tend to spring to mind when we think about the role of commercial actors and behavioural factors in influencing health. And for good reason. In Australia, for instance, smoking is estimated to kill more than 24 000 people each year.1 Alcohol contributes substantially to a wide range of diseases, including cancer, liver disease, heart disease, and suicide and self-harm, and overall accounts for around 4% of the nation’s total disease burden.2 Reducing the consumption of sugar via a sugar-sweetened beverage tax is predicted to substantially reduce the number of cases of type 2 diabetes, heart disease and stroke, while also cutting the prevalence of obesity in children and adolescents.3

Traditionally, scholarship in this area has focused on industries that produce and sell products with obvious health harming impacts. More recently, the understanding of the commercial determinants of health has expanded to encompass the “pathways through which commercial actors drive health and equity”.4 This shift has enabled more deliberate exploration of how many other sectors of the economy can influence health, including gambling, social media, housing and education, to name but a few.5

This issue of the MJA illuminates our evolving understanding of the role that social and commercial factors have on health in Australia. Two articles in this issue address how rising rates of homelessness — which includes sleeping rough, as well as reliance on emergency and temporary accommodation, couch surfing, and substandard housing — demand greater consideration from health policy makers and practitioners. First, Stearn and colleagues6 explain how housing insecurity adversely affects cancer care and outcomes and put forward several possible pathways towards achieving more equitable cancer outcomes for people experiencing homelessness. Second, English and colleagues7 explore the intersection between the worsening climate crisis and homelessness. They outline the evidence on how people experiencing homelessness are more vulnerable than people with secure housing to the health impacts of extreme heat and describe emerging public health responses, including their world first co-designed mobile cooling hub.

Turning to health care, a perspective article by Murphy8 explores the rise in out-of-pocket costs for accessing non-general practitioner specialists. “Doctors have, not unreasonably, had an expectation of earning high incomes, given the training required for each specialty fellow,” Murphy argues. “However, these incomes, and the fees that generate them, have created a number of challenges.” Several possible solutions are discussed, with Murphy c

酒精、烟草、超加工食品和含糖饮料——当我们想到商业行为者和行为因素在影响健康方面的作用时,往往会想到这些有害产品。这是有原因的。例如,在澳大利亚,据估计每年有超过2.4万人死于吸烟酒精在很大程度上导致了一系列疾病,包括癌症、肝病、心脏病、自杀和自残,总体上约占全国疾病总负担的4%通过征收含糖饮料税来减少糖的消费量,预计将大大减少2型糖尿病、心脏病和中风的病例数量,同时还能降低儿童和青少年的肥胖患病率。传统上,这一领域的学术研究主要集中在生产和销售对健康有明显危害的产品的行业。最近,对健康的商业决定因素的理解已扩大到包括“商业行为体推动健康和公平的途径”这种转变使人们能够更审慎地探索经济中有多少其他部门可以影响健康,包括赌博、社交媒体、住房和教育等等。5 .这一期的《澳大利亚健康评估报告》阐明了我们对社会和商业因素对澳大利亚健康所起作用的不断发展的理解。本期的两篇文章讨论了无家可归率的上升——包括露宿街头、依赖紧急和临时住所、沙发冲浪和不合标准的住房——如何要求卫生政策制定者和从业人员更多地考虑。首先,斯登和他的同事解释了住房不安全如何对癌症治疗和结果产生不利影响,并提出了几种可能的途径,使无家可归的人获得更公平的癌症治疗结果。其次,英格利什和他的同事探讨了日益恶化的气候危机和无家可归者之间的交集。他们概述了无家可归者如何比拥有安全住房的人更容易受到极端高温对健康影响的证据,并描述了新兴的公共卫生应对措施,包括他们在世界上第一个共同设计的移动冷却中心。谈到医疗保健,Murphy8的一篇观点文章探讨了非全科医生专家自费费用的上升。墨菲认为:“考虑到每个专业人员需要接受的培训,医生们理所当然地期望获得高收入。”“然而,这些收入以及由此产生的费用带来了许多挑战。”他们讨论了几种可能的解决方案,墨菲总结道:“自我监管是最简单的选择。鉴于社区和政府对这个问题的担忧,专家们应该好好反思他们的收费对病人的影响……(以)改善病人的就诊机会,减少政府干预的风险。”本期MJA的其他工作包括埃格及其同事对青少年吸烟流行趋势的新研究,该研究表明,电子烟可能会减缓澳大利亚的烟草控制进展。此外,Cortes-Ramirez及其同事的一篇叙述性综述研究了采矿活动对澳大利亚人健康的相对未被充分研究的影响,Gong及其同事的整个人口普查数据分析描述了社会经济地位与十种主要慢性疾病流行之间的关系。尽管我们对健康的社会和商业决定因素的了解在不断扩大,但直到最近,新闻媒体行业还很少引起公共卫生学者的注意弗雷德里克斯和他的同事们在本期《美国医学会杂志》上撰文,提出了将新闻业确立为健康决定因素,并将新闻业作为公共健康利益来保护的理由。他们认为:“我们日益不可靠和不安全的新闻和信息环境对卫生部门和社区的健康和福祉产生了深刻而广泛的影响。”然而,“与此同时,公益新闻的能力已经大大削弱”。弗雷德里克斯和他的同事概述了如何应对与健康有关的错误信息和虚假信息的传播,这些信息的焦点往往过于狭隘。诸如改善科学传播或卫生素养等战略是重要的,但它们本身将无法解决所起作用的问题的复杂性和连通性。相反,需要有系统的方法,承认公益新闻在“追究损害新闻和信息系统安全性和可靠性的商业和政治利益”方面的核心作用。
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引用次数: 0
CURE Asthma: a unique opportunity for Australia 治疗哮喘:澳大利亚的独特机会
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70093
Anthony Flynn, Wendy Edmondson, Alan James, Caroline Lodge, Vanessa M McDonald, Christine R Jenkins, John Blakey, Gary P Anderson
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引用次数: 0
The CURE Asthma roadmap 治愈哮喘路线图
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-16 DOI: 10.5694/mja2.70094
Gary P Anderson, Anthony Flynn, Phil G Bardin, John D Blakey, Shyamali C Dharmage, Paul Foster, Peter G Gibson, Adam Jaffe, Alan James, Christine R Jenkins, Sundram Sivamalai, Peter D Sly, Guy B Marks, Vanessa M McDonald, Judy Wetttenhall
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引用次数: 0
The early implementation phase of the Omega-3 Test-and-Treat Program for reducing the risk of preterm birth, South Australia, 2021–22: an implementation evaluation study 降低早产风险的Omega-3测试和治疗计划的早期实施阶段,南澳大利亚,2021-22:实施评估研究。
IF 8.5 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-11-11 DOI: 10.5694/mja2.70101
Karen P Best, Celine Northcott, Lucy A Simmonds, Philippa Middleton, Lisa N Yelland, Vanessa Moffa, Khoa Lam, Penelope Coates, Cornelia Späth, Carol WK Siu, Karen Glover, Rhiannon Smith, Robert Gibson, Maria Makrides
<div> <section> <h3> Objective</h3> <p>To assess the feasibility of embedding omega-3 fatty acid testing and targeted supplementation (the Omega-3 Test-and-Treat Program) into routine antenatal care to reduce the risk of preterm birth.</p> </section> <section> <h3> Study design</h3> <p>Prospective implementation evaluation study, using the Quality Enhancement Research Initiative (QUERI) framework.</p> </section> <section> <h3> Setting, participants</h3> <p>Women with singleton pregnancies undergoing routine antenatal screening during early pregnancy (before 20 weeks’ gestation) and their health care providers, South Australia, 19 April 2021 – 30 June 2022.</p> </section> <section> <h3> Intervention</h3> <p>Addition of omega-3 fatty acid testing option to SA Pathology test referral forms for the South Australian Maternal Serum Antenatal Screening (SAMSAS) program, with the aim of identifying women with low omega-3 fatty acid levels during early pregnancy and providing evidence-based supplementation guidance for reducing the risk of preterm birth.</p> </section> <section> <h3> Main outcome measures</h3> <p>Program feasibility (uptake and fidelity); representativeness of women tested for omega-3 fatty acid status; and omega-3 fatty acid status, by proportion of total serum fatty acids (low, < 3.7%; moderate, 3.7–4.3%; sufficient, > 4.3%).</p> </section> <section> <h3> Results</h3> <p>A total of 4801 requests for omega-3 fatty acid tests (26.1% of 18 362 SAMSAS referrals) were submitted to SA Pathology during the initial implementation phase of the Omega-3 Test-and-Treat Program. The monthly number of test requests increased from 15 (2.4% of 627 SAMSAS referrals) in April 2021 to 340 (29.4% of 1156 SAMSAS referrals) in June 2022. The socio-demographic and clinical characteristics of women referred for omega-3 fatty acid testing were similar to those for women who were not. Serum samples were insufficient for omega-3 fatty acid testing in 19 cases; of the 4782 tests performed, omega-3 fatty acid levels were low in 702 (14.7%), moderate in 1638 (34.2%), and sufficient in 2442 tests (51.1%). Of 5057 samples received by the Omega-3 Laboratory, 4935 (97.6%) were analysed within 72 hours. Thirty-three of 4801 omega-3 fatty acid test referrals (0.7%) were for women beyond 20 weeks of pregnancy; 58 referrals (1.2%) were for women with non-singleton pregn
目的:探讨将omega-3脂肪酸检测和靶向补充(omega-3测试和治疗计划)纳入常规产前保健以降低早产风险的可行性。研究设计:前瞻性实施评估研究,采用质量提高研究倡议(QUERI)框架。背景,参与者:在妊娠早期(妊娠20周之前)接受常规产前检查的单胎妊娠妇女及其保健提供者,南澳大利亚,2021年4月19日至2022年6月30日。干预措施:在南澳大利亚州孕产妇血清产前筛查(SAMSAS)项目的SA病理学检查转诊表中增加了omega-3脂肪酸测试选项,目的是识别怀孕早期omega-3脂肪酸水平低的妇女,并为降低早产风险提供循证补充指导。主要评价指标:项目可行性(接受度和保真度);测试omega-3脂肪酸状态的妇女的代表性;omega-3脂肪酸状态,按总血清脂肪酸的比例(低,4.3%)。结果:在omega-3测试和治疗计划的初始实施阶段,共有4801例omega-3脂肪酸测试请求(18362例SAMSAS转诊患者中的26.1%)提交给SA Pathology。每月的考试申请数量从2021年4月的15个(占627个SAMSAS申请的2.4%)增加到2022年6月的340个(占1156个SAMSAS申请的29.4%)。接受omega-3脂肪酸检测的妇女的社会人口学和临床特征与没有接受omega-3脂肪酸检测的妇女相似。19例患者血清中omega-3脂肪酸检测不足;在进行的4782项测试中,omega-3脂肪酸水平低的有702项(14.7%),中等的有1638项(34.2%),充足的有2442项(51.1%)。在Omega-3实验室收到的5057份样本中,4935份(97.6%)在72小时内进行了分析。在4801例omega-3脂肪酸测试中,有33例(0.7%)是怀孕20周以上的女性;58例转诊(1.2%)是非单胎妊娠妇女。结论:Omega-3测试和治疗计划是一种可行的方法,可以通过有针对性的营养干预来降低早产风险,可以纳入澳大利亚的常规产前保健。
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Medical Journal of Australia
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