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Improvement of Organisms by Biomimetic Mineralization: A Material Incorporation Strategy for Biological Modification 仿生矿化改良生物体:一种生物修饰的材料掺入策略
Pub Date : 2020-07-03 DOI: 10.2139/ssrn.3552444
Yueqi Zhao, R. Tang
Biomineralization, a bio-organism controlled mineral formation process, plays an important role in linking biological organisms and mineral materials in nature. Inspired by biomineralization, biomimetic mineralization is used as a bridge tool to integrate biological organisms and functional materials together, which can be beneficial for the development of diversified functional organism-material hybrids. In this review, recent progresses on the techniques of biomimetic mineralization for organism-material combinations are summarized and discussed. Based upon these techniques, the preparations and applications of virus-, prokaryotes-, and eukaryotes-material hybrids have been presented and they demonstrate the great potentials in the fields of vaccine improvement, cell protection, energy production, environmental and biomedical treatments, etc. We suggest that more researches about functional organism and material combination with more biocompatible techniques should be developed to improve the design and applications of specific organism-material hybrids. These rationally designed organism-material hybrids will shed light on the production of "live materials" with more advanced functions in future. Statement of significance This review summaries the recent attempts on improving biological organisms by their integrations with functional materials, which can be achieved by biomimetic mineralization as the combination tool. The integrated materials, as the artificial shells or organelles, confer diversified functions on the enclosed organisms. The successful constructions of various virus-, prokaryotes-, and eukaryotes-material hybrids have demonstrated the great potentials of the material incorporation strategy in vaccine development, cancer treatment, biological photosynthesis and environment protection etc. The suggested challenges and perspectives indicate more inspirations for the future development of organism-material hybrids.
生物矿化作用是生物有机体控制的矿物形成过程,在自然界中起着连接生物有机体与矿物材料的重要作用。受生物矿化的启发,仿生矿化作为将生物有机体和功能材料整合在一起的桥梁工具,有利于发展多样化的功能有机体-材料杂交体。本文综述了生物与物质结合的仿生矿化技术的最新进展。在这些技术的基础上,病毒、原核生物和真核生物材料杂交体的制备和应用已经得到了介绍,它们在疫苗改良、细胞保护、能源生产、环境和生物医学治疗等领域显示出巨大的潜力。我们建议开展更多的功能生物和材料组合方面的研究,以提高特定生物材料杂交的设计和应用。这些合理设计的生物-材料混合体将为未来生产具有更先进功能的“活材料”提供启示。本文综述了近年来以仿生矿化为组合手段,通过与功能材料的结合来改善生物有机体的研究进展。合成材料,如人造外壳或细胞器,赋予被封闭的生物体多种功能。各种病毒-、原核生物-和真核生物-材料杂交体的成功构建,显示了材料结合策略在疫苗开发、癌症治疗、生物光合作用和环境保护等方面的巨大潜力。提出的挑战和前景为未来生物材料混合材料的发展提供了更多的灵感。
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引用次数: 28
Cluster Model of the Porosity of Spongy Titanium Briquettes at the Stage of Pressing 海绵钛型煤受压阶段孔隙率的聚类模型
Pub Date : 2020-06-30 DOI: 10.15587/1729-4061.2020.206715
L. Klymenko, V. Andreev, O.I. Sluchak, Oleg Pryshchepov, O. Shchesiuk
The main factors of the formation of porosity of pressed products based on spongy titanium were studied. Three types of pores were studied and separated – cluster (in the place of particles), inter-cluster, and natural pores of the material. The cluster models of particles packing at the stages of pressing were developed (from bulk density, or the formation of temporary structures to the formation of stable structures). The number of cluster faces in the models depends on coordination number λ, which means tetrahedral (λ=4) clusters at the initial stage and cuboctahedral (λ=12) at the later ones. Based on the Gaussian rule, for spheres packing, it was found that the most correct form of clusters for later pressing stages is cuboctahedral, as the pores between the spheres at the maximum tight packing with the coordination number of 12 have the shape close to cuboctahedrons and octahedrons, but with concave faces. Based on the difference between the volume of spheres, for which particles and clusters in the model were accepted, based on calculated volumes of intercluster octahedrons and cuboctahedrons, the volume of pores in the shape of the Steiner octahedron or cuboctahedron was calculated. In calculating the strength of adhesion between the particles, the proper porosity of spongy titanium is determined through the assumption that a part of the powder is a conglomerate that is formed from hollow spheres of the regular shape at the stage of titanium reduction by the magnesium thermal method. Accordingly, in the formula for calculating the strength of adhesion, the force that influences a particle will consist of the difference between forces of elastic deformation and the destruction of hollow spheres contained in the deformed volume. The developed models were proved by the results of practical research. Actual measurements show the average exponential ratio of the porosity to pressing pressure, which makes it possible to calculate s maximum inter-cluster porosity at the maximum compaction of 66 % and the compression factor of the studied material of 0.15
研究了海绵状钛压制制品气孔形成的主要因素。研究并分离了三种类型的孔隙——簇状孔隙(代替颗粒)、簇间孔隙和材料的天然孔隙。建立了颗粒在挤压阶段堆积的团簇模型(从体积密度,或临时结构的形成到稳定结构的形成)。模型中的簇面数取决于配位数λ,即初始阶段为四面体(λ=4),后期为立方体(λ=12)。基于高斯规则,对于球体的填充,发现对于后期压制阶段最正确的团簇形式是立方体,因为在最大紧密填充时,配位数为12的球体之间的孔隙具有接近立方体和八面体的形状,但具有凹面。根据模型中可接受的颗粒和团簇球体的体积差异,根据团簇间八面体和立方体的计算体积,计算出斯坦纳八面体或立方体形状的孔隙体积。在计算颗粒间的粘附强度时,假设部分粉末是用镁热法还原钛时由规则形状的空心球体形成的砾岩,从而确定海绵钛的适当孔隙率。因此,在计算粘附强度的公式中,影响颗粒的力将由弹性变形力与变形体积中包含的空心球体的破坏力之差组成。所建立的模型得到了实际研究结果的验证。实际测量结果显示孔隙度与压紧压力的平均指数比,从而可以计算出最大压实度为66%时团簇间的最大孔隙度,所研究材料的压缩系数为0.15
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引用次数: 0
Rheology and Flow of Complex Fluids: Fundamental and Experimental Aspects 流变学和复杂流体的流动:基础和实验方面
Pub Date : 2020-06-30 DOI: 10.2139/ssrn.3639136
A. Maazouz
The study of the rheological behavior of complex fluids in relation to their molecular structure is a primary tool to predict their flow behavior. Such study is often conducted under high shear gradients equivalent to those present in the processes. The ultimate goal of this paper is to introduce the fundamental aspects of shear rheology. The experimental aspects include showing how to establish flow curves (stress versus shear gradients or viscosity versus shear gradients) necessary for any numerical simulation of the flows.
研究复杂流体的流变行为与分子结构的关系是预测其流动行为的主要工具。这种研究通常是在与过程中存在的等高剪切梯度下进行的。本文的最终目的是介绍剪切流变学的基本方面。实验方面包括展示如何建立流动曲线(应力与剪切梯度或粘度与剪切梯度),这是任何流动数值模拟所必需的。
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引用次数: 0
Research of the Milling Process of a Cylindrical Surface by an Oriented Instrument 定向仪铣削圆柱面工艺研究
Pub Date : 2020-06-30 DOI: 10.15587/2706-5448.2020.202793
V. Kalchenko, V. Kalchenko, N. Sira, Ya.V. Kuzhelnyi, Volodymyr Vynnyk
The object of research is the milling process with the crossed axes of the cylindrical surface and the tool. During the research, general modular three-dimensional models of the tool surface, the processes of removing the allowance and the shaping of the cylindrical surface are used on the basis of three unified modules: tool, shaping and orientation. Computer simulation is also used to build a three-dimensional model of the milling process of a cylindrical surface with an oriented tool. A graphic scheme of milling a cylindrical surface with an oriented tool has been created. The developed cylindrical module for shaping the tool surface, which is described by the product of the displacement matrices along the corresponding axes and the surface of the machined part, is represented by the product of the radius of the tool vector and its orientation module in the shaft coordinate system. The resulting graph of the distribution of the specific productivity of the milling process along the tooth profile of the tool during processing with crossed axes of the cutter and part. An analysis of this graph shows that the milling method with an oriented tool makes it possible to increase the accuracy of the shaping process due to uniform wear of the tool. The intersection angle of the cylindrical surface and the tool is also determined, the value of which is taken from the condition of ensuring the maximum removal of the material layer with uniform loading of the end part of the cutter. For this, a three-dimensional model of the process of milling a cylindrical surface with crossed axes of the tool and the part is developed, in which rough milling is carried out by the end part of the tool, and the finish – by the peripheral. In the course of the research, it is found that when finishing milling, the value of the rotation angle of the cutter is taken from the condition that the peripheral part of the cutter is fully loaded. Improving the processing efficiency is achieved by crossing the axes of the tool and the part, which allows to program the intersection point, and uniform wear of the cutter, which improves the quality of the machined surface. It is also possible to use high-speed milling to provide increased processing productivity.
研究的对象是圆柱面与刀具轴向交叉的铣削过程。在研究过程中,在刀具、成形和定位三个统一模块的基础上,采用了刀具面、去除余量和圆柱面成形的通用模块化三维模型。利用计算机仿真建立了定向刀具铣削圆柱面过程的三维模型。建立了用定向刀具铣削圆柱表面的图形方案。所开发的刀面成形圆柱模块,用相应轴向位移矩阵与被加工零件表面的乘积来描述,在轴坐标系中用刀具矢量半径与其方向模块的乘积来表示。在刀具与零件轴向交叉的情况下,铣削过程的比生产率沿刀具齿形的分布图。对该图的分析表明,由于刀具的均匀磨损,使用定向刀具的铣削方法可以提高成形过程的精度。还确定了圆柱面与刀具的交角,其取值是在保证刀具端部均匀载荷下最大去除材料层的条件下取的。为此,建立了刀具与零件轴向交叉的圆柱面铣削过程的三维模型,其中刀具的端部进行粗铣,外围部分进行精铣。在研究过程中发现,在精铣时,刀具旋转角度的取值是在刀具外围部分满载的情况下取的。提高加工效率是通过刀具和零件的轴线交叉来实现的,这样可以对交点进行编程,并且刀具的磨损均匀,从而提高了加工表面的质量。也可以使用高速铣削来提高加工生产率。
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引用次数: 1
Force Calibration of a Hemispherical Model Using Reddy Shock Tube 用Reddy激波管标定半球形模型的力
Pub Date : 2020-06-26 DOI: 10.2139/ssrn.3703919
Samprada S. Kumbhare, Devyani Kumar Kundurthi, J. Sura, G. Joshi
Shock tube study is done to understand the characteristic behavior of various types of shock wave, pressure and temperature variations observed at hypersonic speed. To study these characteristics in an inexpensive and simplified way, an instrument called Reddy Shock tube was designed, also known as Table-Top shock tube. Shock waves are generated purely by the application of manual force. In the test section, a flow of Mach upto 6.5 is generated. The attempt here was made to calculate force acting on a hemispherical model at hypersonic flow regime. It is an impulse facility, where the flow operates only for a fractional second. The pressure transducers were used to characterize the shock wave properties. Similarly, an accelerometer was connected to the model, which determined the acceleration value required to find the axial force.
对激波管进行了研究,以了解在高超声速下观察到的各种类型激波、压力和温度变化的特征行为。为了以一种廉价和简化的方式研究这些特性,设计了一种称为Reddy激波管的仪器,也称为桌面激波管。冲击波纯粹是由人工施加的力产生的。在试验段中,产生了高达6.5马赫的气流。本文试图在高超声速流态下计算作用在半球形模型上的力。这是一个脉冲装置,其中的流体只运行一小部分秒。利用压力传感器对冲击波特性进行了表征。同样地,一个加速度计连接到模型上,它确定了求轴向力所需的加速度值。
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引用次数: 0
Combined Material, Pump Design and Manufacturing Method Gives Good Results in Fertilizer Industry 材料与泵相结合的设计制造方法在肥料工业中取得了良好的效果
Pub Date : 2020-06-26 DOI: 10.2139/ssrn.3636043
Merja Pärssinen
Cost saving is not the best way to achieve good results, but investing in the right products and materials is. Different metallic pump materials and manufacturing methods have been developed for various fertilizer processes. They build on the raw materials used in the production, process conditions in different pumping stages, process know-how, and the material itself. To specify the material of construction based on corrosion resistance alone is not enough, but mechanical properties also need to be considered when selecting pump materials for different pumping stages in the production process for fertilizers. The effect of different components on the abrasion and corrosion resistance in the microstructure of various types of cast irons used in the industry is decisive as well. Pump design features such as flow velocity, wall thickness and seal cavity combined with application knowhow and material selection gives the best result. The development of new coatings and 3D printing technology opens new opportunities for both equipment suppliers and end users.
节约成本并不是取得好结果的最佳途径,但投资于正确的产品和材料才是。针对不同的施肥工艺,开发了不同的金属泵材料和制造方法。它们建立在生产中使用的原材料、不同泵送阶段的工艺条件、工艺诀窍和材料本身的基础上。仅根据耐腐蚀性来指定施工材料是不够的,在选择肥料生产过程中不同泵送阶段的泵材料时,还需要考虑机械性能。在工业上使用的各种类型的铸铁的显微组织中,不同成分对其耐磨性和耐腐蚀性的影响也是决定性的。泵的设计特点,如流速,壁厚和密封腔结合应用技术和材料的选择,使最好的结果。新涂料和3D打印技术的发展为设备供应商和最终用户带来了新的机遇。
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引用次数: 0
Use of Air Cooling Method for Slurry Cooling for WPA Production Units 水渍水生产装置用风冷法进行浆液冷却
Pub Date : 2020-06-26 DOI: 10.2139/ssrn.3636079
E. Kuznetsov, A. Kiselev
One of the most important issues in wet phosphoric acid technology is maintenance of the set temperature of slurry. Excess process heat is taken away mainly by evaporation of water from slurry. There are two main ways of cooling – evaporation under vacuum and air cooling method. Both ways have advantages and disadvantages. The main advantages of air cooling method are: it’s rather simple, and requires low capital cost for implementation, use of cooling water for condensation of secondary steam is excluded, cooling tower isn't required for cooling water, etc. Since 1980-s JSC “NIUIF” is engaged in elaboration and improvement of air cooling systems for slurry cooling. As a result of these researches air cooling units of various types for dihydrate and hemi-hydrate processes of WPA were constructed. Use of air cooling method is an essential part of elaborated by JSC “NIUIF” hemi-hydrate WPA process technology from Kola apatite concentrate, as well as high-temperature dihydrate process from Karatau phosphate rock which are carried out at temperatures of 90-94°C. Modern system of air cooling is comprised of: low pressure (LP 800-1000 mm) slurry supply axial pump of high capacity (5000-10000 m3/h), air cooling unit, FDF and/or IDF. Due to optimization of heat&mass exchange conditions and design of air cooling unit (ACA), moisture saturation of cooling air can be achieved up to high extent (up to 400 g/kg of dry air) that allows to minimize its consumption. High consumption of slurry for cooling provides rather low gradient of temperatures (∆t ≤ 3°C) at inlet and outlet from ACA and rather low manual labor efforts for cleaning of the equipment from incrusting sediment. The loop of supply for cooling can be combined with circulation loop inside the reactor that contributes to homogenization of slurry in reactionary volume. Air cooling units for slurry cooling based on researches by JSC “NIUIF” are successfully introduced at modernized and newly constructed WPA systems in Russia, Belarus, Kazakhstan, Lithuania. WPA single line process system capacity with air cooling of reactors reaches 1500 tpd of Р2О5.
湿式磷酸工艺中最重要的问题之一是保持浆料的设定温度。多余的工艺热量主要通过浆料中的水分蒸发带走。冷却方式主要有真空蒸发和空气冷却两种。两种方式都有优点和缺点。空冷法的主要优点是:操作简单,实施资金成本低,不需要冷却水冷凝二次蒸汽,不需要冷却塔提供冷却水等。自20世纪80年代以来,JSC“NIUIF”一直致力于精细化和改进用于泥浆冷却的空气冷却系统。在此基础上,建立了不同类型的水冷法二水和半水工艺空冷装置。采用风冷法是JSC公司以Kola磷灰石精矿为原料的“NIUIF”半水合WPA工艺技术和以Karatau磷灰岩为原料在90-94℃高温下进行的高温二水合工艺的重要组成部分。现代风冷系统由:低压(LP 800- 1000mm)高容量(5000- 10000m3 /h)浆料供应轴流泵、风冷机组、FDF和/或IDF组成。由于优化了热交换条件和空气冷却装置(ACA)的设计,冷却空气的水分饱和度可以达到很高的程度(高达400g /kg干空气),从而最大限度地减少其消耗。用于冷却的浆料的高消耗提供了ACA入口和出口相当低的温度梯度(∆t≤3°C),并且相当低的人工劳动来清洗设备中的结块沉积物。冷却供给回路可与反应器内循环回路相结合,有利于浆料在反应体积内的均匀化。在俄罗斯、白俄罗斯、哈萨克斯坦、立陶宛等国的现代化和新建水厂系统中,成功地引进了由JSC“NIUIF”研制的用于浆液冷却的空冷机组。带风冷堆的WPA单线工艺系统容量可达1500 tpd Р2О5。
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引用次数: 0
Study of Surface Quality During End Milling of SiC Reinforced Aluminium Metal Matrix Composite SiC增强铝基复合材料立铣削表面质量研究
Pub Date : 2020-06-26 DOI: 10.2139/ssrn.3683054
S. Sagar
In today’s world the composites materials are replacing many conventional materials due to their excellent properties. Aluminum is a less weight and cheap metal that is available in plenty. Silicon carbide is hard abrasive material with good mechanical properties. The aluminum silicon carbide metal matrix composite is finding increased applications in many fields such as automobile and aeronautical applications due to its excellent mechanical properties like high strength, light weight, high specific stiffness and good coefficient of thermal expansion. But their usage is restricted due to the difficulty in the machinability. In this paper two Al/SiC metal matrix composites (Al6061/10-SiCp and Al6061/5-SiCp) by varying the composition of SiC. The composites consist Silicon Carbide (SiC) of 5% and 10% by weight. The composites are prepared by stir casting process. Shell moulding technique is used in manufacturing of the composite materials. The microstructure, tensile strength, compression strength and hardness of the composites are studied. End milling operation is performed on the metal matrix composite slabs by varying the machining parameters. Feed rate and depth of cut were varied by fixing a single spindle speed. The number of experiments is determined using design of experiments (DOE). The effect of the machining parameters on the surface finish is observed by measuring the surface roughness. This process is done on the two metal matrix composites. The effect of SiC percentage in composite and variations in machining parameters on the surface finish was observed.
在当今世界,复合材料以其优异的性能正在取代许多传统材料。铝是一种重量更轻、价格更便宜的金属,而且储量丰富。碳化硅是一种硬质磨料,具有良好的机械性能。铝碳化硅金属基复合材料由于具有高强度、轻量化、高比刚度和良好的热膨胀系数等优异的机械性能,在汽车和航空等许多领域的应用越来越广泛。但由于加工难度大,限制了其使用。本文通过改变SiC的组成制备了两种Al/SiC金属基复合材料(Al6061/10-SiCp和Al6061/5-SiCp)。复合材料由5%和10%重量的碳化硅(SiC)组成。采用搅拌铸造法制备了复合材料。复合材料的制造采用壳体成型技术。研究了复合材料的显微组织、抗拉强度、抗压强度和硬度。通过改变加工参数对金属基复合板材进行立铣削加工。通过固定一个主轴转速来改变进给速度和切削深度。实验数由实验设计(DOE)决定。通过测量表面粗糙度,观察加工参数对表面光洁度的影响。该工艺是在两种金属基复合材料上进行的。观察了复合材料中SiC含量和加工参数的变化对表面光洁度的影响。
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引用次数: 0
Methanol-Assisted Flash Sintering of ZnO 甲醇辅助氧化锌的闪蒸烧结
Pub Date : 2020-06-18 DOI: 10.2139/ssrn.3630430
Jiuyuan Nie, Jian Luo
In a prior work [Nie et al., Scripta Materialia 142, 79-82 (2018)], we have demonstrated that water vapor can trigger flash sintering of ZnO powder pellets at room temperature to achieve ~98% of the theoretical density in 30 seconds without any external furnace heating. Here, we further extend this “water-assisted flash sintering (WAFS)” to “solvent-assistant flash sintering (SAFS)” using methanol as an example. Specifically, we successfully demonstrated that methanol vapor can also trigger a flash at room temperature to subsequently sinter ZnO to ~ 93 – 96% of the theoretical density in <30 seconds. We further revealed a couple of interesting new phenomena, including bifurcation in kinetic pathways and self-termination of flash sintering.
在之前的一项研究中[Nie et al., Scripta Materialia 142, 79-82(2018)],我们证明了水蒸气可以在室温下触发ZnO粉末颗粒的闪速烧结,在30秒内达到理论密度的98%,而无需任何外部炉加热。在这里,我们以甲醇为例,将这种“水助速烧结(WAFS)”进一步扩展为“溶剂助速烧结(SAFS)”。具体来说,我们成功地证明了甲醇蒸气也可以在室温下触发闪光,随后在<30秒内将ZnO烧结到理论密度的~ 93 - 96%。我们进一步发现了一些有趣的新现象,包括动力学路径的分岔和闪速烧结的自终止。
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引用次数: 0
Process Digitalisation 过程数字化
Pub Date : 2020-06-15 DOI: 10.48216/9788269203325ch14
J. Lamb
Process plant control and operations have undergone significant developments over early analogue regulatory schemes. Computer-based supervisory regulation was attempted in the late 1950s. The microprocessor implemented the first distributed control systems in the 1970s. In this chapter, an overview of current digitalization approaches to manufacturing and production is given for process plant control in general.
与早期的模拟监管方案相比,过程工厂控制和操作经历了重大发展。以计算机为基础的监管在20世纪50年代末进行了尝试。微处理器在20世纪70年代实现了第一个分布式控制系统。在本章中,概述了目前制造和生产的数字化方法,一般用于过程工厂控制。
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引用次数: 0
期刊
MatSciRN: Process & Device Modeling (Topic)
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