Pub Date : 2023-05-25DOI: 10.1080/10667857.2023.2214775
Bolin Sun, Xizeng Chen, Huiqiang Wang
ABSTRACT Recently, the application of flexible sensors in mechanical equipment has attracted widespread attention. However, the design of vibration sensor materials and structures for complex mechanical environments still faces challenges. Hence, we proposed an annular structure CCTO/PDMS-based triboelectric nanogenerator (CP-TENG) as self-powered triboelectric automotive bolt tightness sensor. Due to the high dielectric properties of CCTO/PDMS film, the CP-TENG device can obtain high electrical output performance to achieve high sensitivity sensing. Through the annular structure design, CP-TENG devices can be integrated into bolt fittings with good structural compatibility. The output voltage and current of CP-TENG can monitor the different accelerations borne by the bolts from 9 to 60 m/s2. Moreover, by installing on the gasket, the CP-TENG device can also monitor bolt looseness to achieve early warning of the safety status of automotive components. This research can promote the development of self-powered sensor in the field of automotive bolt vibration monitoring.
{"title":"A triboelectric vibration sensor for detecting loose bolts in automobile","authors":"Bolin Sun, Xizeng Chen, Huiqiang Wang","doi":"10.1080/10667857.2023.2214775","DOIUrl":"https://doi.org/10.1080/10667857.2023.2214775","url":null,"abstract":"ABSTRACT Recently, the application of flexible sensors in mechanical equipment has attracted widespread attention. However, the design of vibration sensor materials and structures for complex mechanical environments still faces challenges. Hence, we proposed an annular structure CCTO/PDMS-based triboelectric nanogenerator (CP-TENG) as self-powered triboelectric automotive bolt tightness sensor. Due to the high dielectric properties of CCTO/PDMS film, the CP-TENG device can obtain high electrical output performance to achieve high sensitivity sensing. Through the annular structure design, CP-TENG devices can be integrated into bolt fittings with good structural compatibility. The output voltage and current of CP-TENG can monitor the different accelerations borne by the bolts from 9 to 60 m/s2. Moreover, by installing on the gasket, the CP-TENG device can also monitor bolt looseness to achieve early warning of the safety status of automotive components. This research can promote the development of self-powered sensor in the field of automotive bolt vibration monitoring.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"52 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73910907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.1080/10667857.2023.2214776
Junhua Gao, Xiaofeng Zhao, Zhengfu Cheng, L. Tian
ABSTRACT Epitaxial graphene on semiconductor films has potential for various applications due to its thermoelectric properties. We investigated factors affecting its thermo power using a solid-state physics approach, considering the interaction between the substrate and graphene, and exploring the effects of chemical potential, temperature, anharmonic vibrations of atoms, phonon-drag, and film thickness. Our results show that anharmonic effects significantly enhance the thermopower caused by electrons, especially at higher temperatures. Additionally, we observed an increase in total thermopower due to phonon-drag, although it has negligible effects at or above room temperature. We found that the thermopower on size-quantized semiconductor films is significantly higher than on metal conductor films and bulk semiconductor substrates. Decreasing the film thickness further increases the thermo power, providing an effective way to enhance the thermo electric properties of epitaxial graphene. Our findings contribute to a better understanding of the thermoelectric properties of epitaxial graphene on semiconductor films and offer valuable insights for future applications.
{"title":"Thermoelectric transport properties of semiconductor film-based epitaxial monolayer graphene","authors":"Junhua Gao, Xiaofeng Zhao, Zhengfu Cheng, L. Tian","doi":"10.1080/10667857.2023.2214776","DOIUrl":"https://doi.org/10.1080/10667857.2023.2214776","url":null,"abstract":"ABSTRACT Epitaxial graphene on semiconductor films has potential for various applications due to its thermoelectric properties. We investigated factors affecting its thermo power using a solid-state physics approach, considering the interaction between the substrate and graphene, and exploring the effects of chemical potential, temperature, anharmonic vibrations of atoms, phonon-drag, and film thickness. Our results show that anharmonic effects significantly enhance the thermopower caused by electrons, especially at higher temperatures. Additionally, we observed an increase in total thermopower due to phonon-drag, although it has negligible effects at or above room temperature. We found that the thermopower on size-quantized semiconductor films is significantly higher than on metal conductor films and bulk semiconductor substrates. Decreasing the film thickness further increases the thermo power, providing an effective way to enhance the thermo electric properties of epitaxial graphene. Our findings contribute to a better understanding of the thermoelectric properties of epitaxial graphene on semiconductor films and offer valuable insights for future applications.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"4 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84441035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-24DOI: 10.1080/10667857.2023.2211374
A. Krivenko, N. S. Komarova, I. Kostanovskiy, D. Stolyarov, Y.M. Shul’ga, S. Savilov, R. Novotortsev, Y. Dobrovolsky, S. Aldoshin, J. Ni
ABSTRACT Electrochemical behaviour of 4.8 ± 0.2 nm graphene films on nickel and copper foams was investigated by cyclic voltammetry (CV). The graphene films were prepared by chemical vapor deposition and characterized by electron energy loss spectroscopy, elastic peak electron spectroscopy, scanning electron microscopy and X-ray photoelectron spectroscopy. The CV of the [Ru(NH3)6]+2/+3 redox reaction was performed using these substrates. The obtained results demonstrated a high continuity of the deposited graphene film and independence of the electron transfer rate on them from the metal substrate used. The rate of outer-sphere electron transfer on the graphene surface appeared to be substantially less than that on the polished glassy carbon. Partial splitting of graphene layers due to wedged action of 2D adsorption layers, formed by camphor solution, led to the increase in double-layer capacitance.
{"title":"Features of electrochemical behavior of graphene films on metal foams","authors":"A. Krivenko, N. S. Komarova, I. Kostanovskiy, D. Stolyarov, Y.M. Shul’ga, S. Savilov, R. Novotortsev, Y. Dobrovolsky, S. Aldoshin, J. Ni","doi":"10.1080/10667857.2023.2211374","DOIUrl":"https://doi.org/10.1080/10667857.2023.2211374","url":null,"abstract":"ABSTRACT Electrochemical behaviour of 4.8 ± 0.2 nm graphene films on nickel and copper foams was investigated by cyclic voltammetry (CV). The graphene films were prepared by chemical vapor deposition and characterized by electron energy loss spectroscopy, elastic peak electron spectroscopy, scanning electron microscopy and X-ray photoelectron spectroscopy. The CV of the [Ru(NH3)6]+2/+3 redox reaction was performed using these substrates. The obtained results demonstrated a high continuity of the deposited graphene film and independence of the electron transfer rate on them from the metal substrate used. The rate of outer-sphere electron transfer on the graphene surface appeared to be substantially less than that on the polished glassy carbon. Partial splitting of graphene layers due to wedged action of 2D adsorption layers, formed by camphor solution, led to the increase in double-layer capacitance.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"7 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81935420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-23DOI: 10.1080/10667857.2023.2216529
R. Misra, A. Boriek
ABSTRACT The interaction of nanostructured surfaces with cells is complex and has a profound impact on the behaviour of cells by influencing their adhesion, migration, proliferation, and differentiation. Our studies highlighted the contrasting effects of nanostructured and microstructured surfaces on biological functions. Such contrasting effects include the relative influence of physical and chemical attributes of the nanoscale surface compared to the microscale counterpart. These attributes lead to an altered cellular activity at the bio-nano interface through modulating cell adhesion, proliferation of cells and synthesis of functional proteins. Physical and chemical changes induced by the nanostructure are likely to promote cell adhesion, without introducing chemical functionalities on the surface. This represents a significant advance beyond guiding the tailoring of cellular functionality at the bio-nano surface. This would yield an improved understanding of a rational design of biotic/abiotic interfaces that can promote optimal biological responses, leading to the development of new biomedical technologies.
{"title":"Mechanistic understanding of the interaction of cells with nanostructured surfaces within the framework of biological functions","authors":"R. Misra, A. Boriek","doi":"10.1080/10667857.2023.2216529","DOIUrl":"https://doi.org/10.1080/10667857.2023.2216529","url":null,"abstract":"ABSTRACT The interaction of nanostructured surfaces with cells is complex and has a profound impact on the behaviour of cells by influencing their adhesion, migration, proliferation, and differentiation. Our studies highlighted the contrasting effects of nanostructured and microstructured surfaces on biological functions. Such contrasting effects include the relative influence of physical and chemical attributes of the nanoscale surface compared to the microscale counterpart. These attributes lead to an altered cellular activity at the bio-nano interface through modulating cell adhesion, proliferation of cells and synthesis of functional proteins. Physical and chemical changes induced by the nanostructure are likely to promote cell adhesion, without introducing chemical functionalities on the surface. This represents a significant advance beyond guiding the tailoring of cellular functionality at the bio-nano surface. This would yield an improved understanding of a rational design of biotic/abiotic interfaces that can promote optimal biological responses, leading to the development of new biomedical technologies.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"28 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77879194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-19DOI: 10.1080/10667857.2023.2215038
M. Weaver, A. Maldonado, J. Bañuelos, R. Misra
ABSTRACT Currently, there is a significant interest in magnesium (Mg) alloys for structural and functional applications. Mg alloys are lightweight materials (1.7–2.0 g/cm3), whose density is significantly lesser than that of titanium alloys and stainless steels. Furthermore, from the perspective of biomedical devices, they are biodegradable, bioresorbable and biocompatible. The objective of this work is to investigate the transition from grain boundary precipitation behaviour in the as-cast alloy to nanoscale precipitation during triaxial forging, with particular emphasis on exploring the application of small-angle X-ray scattering technique to investigate nanoscale precipitation and complement with the conventional approach of X-ray diffraction and electron microscopy.
{"title":"On precipitation hardening behaviour in a triaxial forged Mg-2Zn-2Gd alloy and relationship to mechanical properties","authors":"M. Weaver, A. Maldonado, J. Bañuelos, R. Misra","doi":"10.1080/10667857.2023.2215038","DOIUrl":"https://doi.org/10.1080/10667857.2023.2215038","url":null,"abstract":"ABSTRACT Currently, there is a significant interest in magnesium (Mg) alloys for structural and functional applications. Mg alloys are lightweight materials (1.7–2.0 g/cm3), whose density is significantly lesser than that of titanium alloys and stainless steels. Furthermore, from the perspective of biomedical devices, they are biodegradable, bioresorbable and biocompatible. The objective of this work is to investigate the transition from grain boundary precipitation behaviour in the as-cast alloy to nanoscale precipitation during triaxial forging, with particular emphasis on exploring the application of small-angle X-ray scattering technique to investigate nanoscale precipitation and complement with the conventional approach of X-ray diffraction and electron microscopy.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"87 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81184478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-25DOI: 10.1080/10667857.2023.2204292
Shangfu Gao, S. Li, Jiazhe Gao, Xuehua Liu, Chunfu Lin
ABSTRACT Li2TiSiO5 is a ‘zero-strain’ anode material with a large theoretical capacity, appropriate operation potential, and good cyclability. However, its low electronic conductivity negatively affects its practical capacity and rate performance. Herein, we improve the electrochemical performance of Li2TiSiO5 by carbon-coating and nanosizing dual modifications, and further explore its lithium-storage and ‘zero-strain’ mechanisms by in-situ XRD. Within 0.2–3.0 V, the carbon-coated Li2TiSiO5 nanowires deliver a large reversible capacity of 257 mAh g−1, high rate performance with a 5000 mA g−1 vs. 50 mA g−1 capacity ratio of 71.6%, and excellent cyclability with 90.0% capacity retention at 5000 mA g−1 over 4000 cycles. The special crystal structure of Li2TiSiO5 with electrochemical active TiO6 octahedra surrounded by inactive SiO4 and LiO6 polyhedra can effectively strengthen the volume-buffering capability, resulting in the ‘zero-strain’ behaviour with a tiny lattice-volume change of only 0.41%. Therefore, this dual-modified Li2TiSiO5 material has great practicability for high-performance lithium storage.
{"title":"Carbon coated “zero-strain” Li2TiSiO5 nanowires for high-performance lithium storage","authors":"Shangfu Gao, S. Li, Jiazhe Gao, Xuehua Liu, Chunfu Lin","doi":"10.1080/10667857.2023.2204292","DOIUrl":"https://doi.org/10.1080/10667857.2023.2204292","url":null,"abstract":"ABSTRACT Li2TiSiO5 is a ‘zero-strain’ anode material with a large theoretical capacity, appropriate operation potential, and good cyclability. However, its low electronic conductivity negatively affects its practical capacity and rate performance. Herein, we improve the electrochemical performance of Li2TiSiO5 by carbon-coating and nanosizing dual modifications, and further explore its lithium-storage and ‘zero-strain’ mechanisms by in-situ XRD. Within 0.2–3.0 V, the carbon-coated Li2TiSiO5 nanowires deliver a large reversible capacity of 257 mAh g−1, high rate performance with a 5000 mA g−1 vs. 50 mA g−1 capacity ratio of 71.6%, and excellent cyclability with 90.0% capacity retention at 5000 mA g−1 over 4000 cycles. The special crystal structure of Li2TiSiO5 with electrochemical active TiO6 octahedra surrounded by inactive SiO4 and LiO6 polyhedra can effectively strengthen the volume-buffering capability, resulting in the ‘zero-strain’ behaviour with a tiny lattice-volume change of only 0.41%. Therefore, this dual-modified Li2TiSiO5 material has great practicability for high-performance lithium storage.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"24 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75602217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-12DOI: 10.1080/10667857.2023.2200660
Qiang Li, C. Jiang, Ye Du
ABSTRACT In this paper, molecular dynamics simulation method was used to establish the atomic model of high entropy alloy. The effect of strain rate on the microstructure evolution and dislocation motion of FeNiCoCrCu high entropy alloy was studied by applying tension and compression loads at different strain rates. The results show that the stress–strain curve of FeNiCoCrCu high entropy alloy presents three stages of elastic deformation, yield and plastic deformation under high strain rate. Under tensile load, Frank dislocation causes plastic deformation of the material, and the dislocation reaction between Shockley dislocation and Hirth dislocation generates Stair-rod dislocation. The mechanism of stress relaxation of materials under compression load is the formation of stacking faults. One of the mechanisms of strain hardening of materials is the formation of twins. In addition, stacking faults intersect with each other to produce dislocation reactions, which generate Stair-rod dislocations, maintaining the development of strain hardening effect.
{"title":"Molecular dynamics study on dynamic mechanical behaviour of FeCoCrCuNi high entropy alloy","authors":"Qiang Li, C. Jiang, Ye Du","doi":"10.1080/10667857.2023.2200660","DOIUrl":"https://doi.org/10.1080/10667857.2023.2200660","url":null,"abstract":"ABSTRACT In this paper, molecular dynamics simulation method was used to establish the atomic model of high entropy alloy. The effect of strain rate on the microstructure evolution and dislocation motion of FeNiCoCrCu high entropy alloy was studied by applying tension and compression loads at different strain rates. The results show that the stress–strain curve of FeNiCoCrCu high entropy alloy presents three stages of elastic deformation, yield and plastic deformation under high strain rate. Under tensile load, Frank dislocation causes plastic deformation of the material, and the dislocation reaction between Shockley dislocation and Hirth dislocation generates Stair-rod dislocation. The mechanism of stress relaxation of materials under compression load is the formation of stacking faults. One of the mechanisms of strain hardening of materials is the formation of twins. In addition, stacking faults intersect with each other to produce dislocation reactions, which generate Stair-rod dislocations, maintaining the development of strain hardening effect.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"11 3 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79577551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.1080/10667857.2023.2199581
Minhui Zhang, Jian Lin, Song Ye, Deping Wang, Aihua Yao, Xuanyu Zhang, Rui Wu, Chengyun Jin
Degradation behaviour of bioactive glass (bioglass) is one of the most important factors affecting bone repair, because an excellent and controllable degradation rate can match the rate of new bone formation. In this research, the derived borosilicate bioglasses based on the 6Na2O-8K2O-8MgO-22CaO-18B2O3-54SiO2-2P2O5 component were synthesized. The effects of B2O3 on the structure, degradation behaviour and cytocompatibility of borosilicate bioglasses were systematically studied. The results showed that with B2O3 addition, the network-forming units became diversified and part of BO4 units transformed into BO3 units. These factors weakened the chemical durability of borosilicate bioglass, thus accelerating the bioglass shedding and altering the ions release, especially B. This study provides a theoretical basis for designing borosilicate bioglass with adjustable degradation rate and ion release behaviour to meet the diverse needs of clinical bone repair.
{"title":"The effects of boron trioxide on the structure and degradation behaviour of borosilicate bioactive glass","authors":"Minhui Zhang, Jian Lin, Song Ye, Deping Wang, Aihua Yao, Xuanyu Zhang, Rui Wu, Chengyun Jin","doi":"10.1080/10667857.2023.2199581","DOIUrl":"https://doi.org/10.1080/10667857.2023.2199581","url":null,"abstract":"Degradation behaviour of bioactive glass (bioglass) is one of the most important factors affecting bone repair, because an excellent and controllable degradation rate can match the rate of new bone formation. In this research, the derived borosilicate bioglasses based on the 6Na2O-8K2O-8MgO-22CaO-18B2O3-54SiO2-2P2O5 component were synthesized. The effects of B2O3 on the structure, degradation behaviour and cytocompatibility of borosilicate bioglasses were systematically studied. The results showed that with B2O3 addition, the network-forming units became diversified and part of BO4 units transformed into BO3 units. These factors weakened the chemical durability of borosilicate bioglass, thus accelerating the bioglass shedding and altering the ions release, especially B. This study provides a theoretical basis for designing borosilicate bioglass with adjustable degradation rate and ion release behaviour to meet the diverse needs of clinical bone repair.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135693611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-30DOI: 10.1080/10667857.2023.2196490
Gauri Chavan, D. Das
ABSTRACT Performing wet bench experiments to search for lead molecules for drug delivery is a long and tedious process where computational tools have played a crucial role. Molecular docking studies have been carried out for selecting the nanocarrier, and the results of the computational studies have been validated using the model protein Ova albumin and anticancer drug 5-Fluorouracil (5-FU) with mesoporous silica (MSNPs) and chitosan nanoparticles (CSNPs) as the nanocarriers. Formulated nanocarriers were tested for in-vitro release, which showed a sustained release of the drugs. In-vitro studies on the lung cancer cell line A459 revealed excellent biocompatibility and non-toxic nature of the designed drug delivery system. This chitosan nanoparticle-based drug delivery system could have the potential for chemotherapeutic treatment of cancer.
{"title":"Design and characterizations of pH-responsive drug delivery vehicles using molecular docking","authors":"Gauri Chavan, D. Das","doi":"10.1080/10667857.2023.2196490","DOIUrl":"https://doi.org/10.1080/10667857.2023.2196490","url":null,"abstract":"ABSTRACT Performing wet bench experiments to search for lead molecules for drug delivery is a long and tedious process where computational tools have played a crucial role. Molecular docking studies have been carried out for selecting the nanocarrier, and the results of the computational studies have been validated using the model protein Ova albumin and anticancer drug 5-Fluorouracil (5-FU) with mesoporous silica (MSNPs) and chitosan nanoparticles (CSNPs) as the nanocarriers. Formulated nanocarriers were tested for in-vitro release, which showed a sustained release of the drugs. In-vitro studies on the lung cancer cell line A459 revealed excellent biocompatibility and non-toxic nature of the designed drug delivery system. This chitosan nanoparticle-based drug delivery system could have the potential for chemotherapeutic treatment of cancer.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"2 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82355361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-29DOI: 10.1080/10667857.2023.2196165
R. Han, Yan Yan, Qian Yu, Zeping Zhang, Qiang Wang, Rui Yang, Y. Bai, Xing Zhang
ABSTRACT Intracranial vascular stent-assisted coil embolization has been widely used for intracranial vascular aneurysm. However, there are serious complication risks, such as thromboembolism, stent migration and spring coil prolapse, due to the inappropriate radial force, poor wall apposition and oversized mesh. Therefore, a locally-reinforced intracranial vascular stent was designed to improve the radial force and wall apposition performance. Based on finite element analysis and substantial measurements, the local radial force has improved 38.9% and thestability of the coil embolism has been enhanced as well. The releasing test in vitro suggests the stent can adhere to the vascular wall very well without the ‘Gator backing’ phenomenon. Furthermore, the implanting test in vivo shows complete endothelialization without restenosis and hyperplasia in 4 weeks. The outcomes of this study provide optimal design of the locally reinforced nitinol stent used for intracranial aneurysm therapy with reduced risks of vascular embolism and haemorrhagic apoplexy after implantation.
{"title":"Fabrication of the locally reinforced open-cell nitinol stents for intracranial vascular aneurysm","authors":"R. Han, Yan Yan, Qian Yu, Zeping Zhang, Qiang Wang, Rui Yang, Y. Bai, Xing Zhang","doi":"10.1080/10667857.2023.2196165","DOIUrl":"https://doi.org/10.1080/10667857.2023.2196165","url":null,"abstract":"ABSTRACT Intracranial vascular stent-assisted coil embolization has been widely used for intracranial vascular aneurysm. However, there are serious complication risks, such as thromboembolism, stent migration and spring coil prolapse, due to the inappropriate radial force, poor wall apposition and oversized mesh. Therefore, a locally-reinforced intracranial vascular stent was designed to improve the radial force and wall apposition performance. Based on finite element analysis and substantial measurements, the local radial force has improved 38.9% and thestability of the coil embolism has been enhanced as well. The releasing test in vitro suggests the stent can adhere to the vascular wall very well without the ‘Gator backing’ phenomenon. Furthermore, the implanting test in vivo shows complete endothelialization without restenosis and hyperplasia in 4 weeks. The outcomes of this study provide optimal design of the locally reinforced nitinol stent used for intracranial aneurysm therapy with reduced risks of vascular embolism and haemorrhagic apoplexy after implantation.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"15 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82553918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：