In the realm of petrochemical and other industries, metal materials face threats such as impact and high-temperature electrochemical corrosion. Consequently, there has been significant attention towards organic coatings that effectively attenuate impact forces while simultaneously providing a barrier against corrosive agents. The thermosetting phenolic resin 2130, known for the facile curing process, exceptional thermal stability, water resistance, corrosion resistance, and superior mechanical properties post-curing, finds extensive applications in the field of coatings. To address the challenge of depositing a complete and uniform resin coating on complex workpieces, coatings with varying thicknesses on the surface of 304 stainless steel were deposited via rotary evaporation combined with long-term low-temperature drying. The relationship between coating thickness and mechanical properties, as well as corrosion resistance, was investigated and analyzed through a comprehensive approach involving mechanical testing, electrochemical analysis, and long-term service weight loss assessment. The results demonstrated that the coatings deposited on the metal surface exhibited excellent integrity and compactness. Moreover, an increase in coating thickness led to a significant reduction in material corrosion rate. The coatings exhibited excellent substrate adhesion and flexibility, thereby providing effective protection against impact on the metal substrate. The relationship between the thickness of the coating and the surface roughness was evident, while the flexibility of the coating first increased and then decreased with the increase of coating thickness. When the coating thickness was 7 μm, the maximum surface roughness of the coating measured 0.44 μm. Under these conditions, the impact toughness of the coating reached the peak, exhibiting a ductile fracture mode and showcasing superior comprehensive mechanical properties. The findings of this study will offer theoretical support for the investigation and formulation of resin coatings in subsequent industrial production.
{"title":"Effect of Phenolic Resin Coating Thickness on Mechanical Properties and Corrosion Resistance of Metal Materials","authors":"Diyao Zhang, L. Yuan, Jingkun Yu","doi":"10.37358/mp.23.4.5684","DOIUrl":"https://doi.org/10.37358/mp.23.4.5684","url":null,"abstract":"\u0000In the realm of petrochemical and other industries, metal materials face threats such as impact and high-temperature electrochemical corrosion. Consequently, there has been significant attention towards organic coatings that effectively attenuate impact forces while simultaneously providing a barrier against corrosive agents. The thermosetting phenolic resin 2130, known for the facile curing process, exceptional thermal stability, water resistance, corrosion resistance, and superior mechanical properties post-curing, finds extensive applications in the field of coatings. To address the challenge of depositing a complete and uniform resin coating on complex workpieces, coatings with varying thicknesses on the surface of 304 stainless steel were deposited via rotary evaporation combined with long-term low-temperature drying. The relationship between coating thickness and mechanical properties, as well as corrosion resistance, was investigated and analyzed through a comprehensive approach involving mechanical testing, electrochemical analysis, and long-term service weight loss assessment. The results demonstrated that the coatings deposited on the metal surface exhibited excellent integrity and compactness. Moreover, an increase in coating thickness led to a significant reduction in material corrosion rate. The coatings exhibited excellent substrate adhesion and flexibility, thereby providing effective protection against impact on the metal substrate. The relationship between the thickness of the coating and the surface roughness was evident, while the flexibility of the coating first increased and then decreased with the increase of coating thickness. When the coating thickness was 7 μm, the maximum surface roughness of the coating measured 0.44 μm. Under these conditions, the impact toughness of the coating reached the peak, exhibiting a ductile fracture mode and showcasing superior comprehensive mechanical properties. The findings of this study will offer theoretical support for the investigation and formulation of resin coatings in subsequent industrial production.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sana Ben Khlifa, Ltaief Lammari, Wajdi Chtourou, H. Kharroubi
This article presents a finite element study based on tests of characterizations to find the properties of the materials studied, the injection-blowing technique, chosen in this case, is characterized by the bi-axial of the material, and one benefits from the orientation of the macromolecules in the directions of use of the material. The objective of this work is to link all the mechanical and thermal parameters during the treatment of molten polymer materials subjected to high-stress rates that can lead to significant temperature increases due to viscous heating in the order of 200�C. Predicting the temperature range is essential for good temperature control and is a major factor in determining the quality of the final product. This forces us to choose an adequate law of behavior, capable of translating the mechanical evolution under the thermal effect while explaining the rheological response of the viscoelastic metal. So this process is usually accompanied by geometric defects resulting from the original residual stresses cooling speed and the process itself. In the packaging of food products, as in this case, the bottles require to have a stable filling and a certain storage capacity.
{"title":"Finite Element Modeling of the Thermomechanical Behavior of Polyethylene","authors":"Sana Ben Khlifa, Ltaief Lammari, Wajdi Chtourou, H. Kharroubi","doi":"10.37358/mp.23.4.5686","DOIUrl":"https://doi.org/10.37358/mp.23.4.5686","url":null,"abstract":"\u0000This article presents a finite element study based on tests of characterizations to find the properties of the materials studied, the injection-blowing technique, chosen in this case, is characterized by the bi-axial of the material, and one benefits from the orientation of the macromolecules in the directions of use of the material. The objective of this work is to link all the mechanical and thermal parameters during the treatment of molten polymer materials subjected to high-stress rates that can lead to significant temperature increases due to viscous heating in the order of 200�C. Predicting the temperature range is essential for good temperature control and is a major factor in determining the quality of the final product. This forces us to choose an adequate law of behavior, capable of translating the mechanical evolution under the thermal effect while explaining the rheological response of the viscoelastic metal. So this process is usually accompanied by geometric defects resulting from the original residual stresses cooling speed and the process itself. In the packaging of food products, as in this case, the bottles require to have a stable filling and a certain storage capacity.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne-Marie Beatrice Poenariu, Roberto Angelo Postelnicu, M. Ciocîlteu, Gabriela Rau, Mariana Popescu, A. Simionescu, Ionela Andreea Neacsu, C. Nicolicescu, D. Amzoiu
Combining polimers with polyphenols such as gallic acid opens up new directions in healthcare system. By encapsulating secondary metabollites within PLGA nanoparticles, we tried to enhance their stability, solubility, and obtain a targeted delivery system. In this study, we synthesized a PLGA-gallic acid sustained release system, using the solvent evaporation method. This approach improved the therapeutic efficacy of gallic acid. The numerical distribution showed that most PLGA-GA nanoparticles have a size of 10 nm. Through the method of solvent evaporation, an incorporation efficiency of 49% was obtained.
{"title":"PLGA - gallic Acid Advanced Drug Delivery System as New Functional Material","authors":"Anne-Marie Beatrice Poenariu, Roberto Angelo Postelnicu, M. Ciocîlteu, Gabriela Rau, Mariana Popescu, A. Simionescu, Ionela Andreea Neacsu, C. Nicolicescu, D. Amzoiu","doi":"10.37358/mp.23.4.5688","DOIUrl":"https://doi.org/10.37358/mp.23.4.5688","url":null,"abstract":"\u0000Combining polimers with polyphenols such as gallic acid opens up new directions in healthcare system. By encapsulating secondary metabollites within PLGA nanoparticles, we tried to enhance their stability, solubility, and obtain a targeted delivery system. In this study, we synthesized a PLGA-gallic acid sustained release system, using the solvent evaporation method. This approach improved the therapeutic efficacy of gallic acid. The numerical distribution showed that most PLGA-GA nanoparticles have a size of 10 nm. Through the method of solvent evaporation, an incorporation efficiency of 49% was obtained.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139450272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virtual reality technologies are important auxiliary tools in the process of learning and acquiring the manual skills necessary for clinical maneuvers in dental prosthodontics. This study shows the particularities in the use of the virtual simulation system designed for dental prosthodontics, compared to the classically preparations performed on resin models. The interactively simulation systems reproduce real clinical situations in which students practice specific dental prosthetics maneuvers. Resin models do not reproduce the accuracy of the dental structures at the time of the preparation. The advantages of using virtual technology are efficient clinical training, allowing for repeatability, self-assessment of procedures and the acquisition of manual skills. In this way, the advantages conferred by virtual simulators are superior to those resulting from the use of resin models in the acquirement of manual skills.
{"title":"Virtual Preparations Versus Classic Preparations on Resin Models in Prosthodontics","authors":"Simona andreea Sandu","doi":"10.37358/mp.23.4.5692","DOIUrl":"https://doi.org/10.37358/mp.23.4.5692","url":null,"abstract":"\u0000Virtual reality technologies are important auxiliary tools in the process of learning and acquiring the manual skills necessary for clinical maneuvers in dental prosthodontics. This study shows the particularities in the use of the virtual simulation system designed for dental prosthodontics, compared to the classically preparations performed on resin models. The interactively simulation systems reproduce real clinical situations in which students practice specific dental prosthetics maneuvers. Resin models do not reproduce the accuracy of the dental structures at the time of the preparation. The advantages of using virtual technology are efficient clinical training, allowing for repeatability, self-assessment of procedures and the acquisition of manual skills. In this way, the advantages conferred by virtual simulators are superior to those resulting from the use of resin models in the acquirement of manual skills.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mihaela Aradoaei, A. Lucaci, R. Ciobanu, Cristina-Mihaela Schreiner, Bogdan-George Rusu, G. Hitruc, Magdalena Aflori, Marius Paulet, A. Caramitu, A. Borş
The piezocomposites from poly-(vinylidene fluoride) (PVDF) with BaTiO3 (BT) are largely presented in literature, but the composites from polydimethylsiloxane (PDMS) with BT consist a very new scientific preoccupation. The novelty of the paper lies in a new simpler route of preparation of the two composites with PDMS and respectively PVDF matrix, with tailored deposition on specific substrates for microelectronic use (e.g. indium-tin-oxide ITO/glass, Si/Pt, polyethylene terephthalate PET), along with an extensive comparation of their dielectric features, a consistent comparison of the influence of polymer matrix upon the piezoelectric features, and a demonstration of direct use for microelectronic applications of the composites of BT with PDMS. An interesting effect is observed around 100 kHz domain, determined by the activity and architecture of BT particles mainly for the BT-PDMS composites, which induce an additional ionic-dipolar conjugated polarization, as a displacement due to the balance between the resonance and anti-resonance frequency. Such phenomena explain the potential use of such composites as resonators/filters, and BT-PDMS composites should be further investigated for tailored applications in radiofrequency electronic field. We can appreciate that superior piezoelectric features are offered by the composites of BT with PDMS, comparing to the composites with PVDF, which means that the composites of BT with PDMS were worth to study, leading to more versatile variants of electronic characteristics and with superior values.
{"title":"Piezoelectric thin Film Composites with BaTiO3 for Microelectronics","authors":"Mihaela Aradoaei, A. Lucaci, R. Ciobanu, Cristina-Mihaela Schreiner, Bogdan-George Rusu, G. Hitruc, Magdalena Aflori, Marius Paulet, A. Caramitu, A. Borş","doi":"10.37358/mp.23.4.5683","DOIUrl":"https://doi.org/10.37358/mp.23.4.5683","url":null,"abstract":"\u0000The piezocomposites from poly-(vinylidene fluoride) (PVDF) with BaTiO3 (BT) are largely presented in literature, but the composites from polydimethylsiloxane (PDMS) with BT consist a very new scientific preoccupation. The novelty of the paper lies in a new simpler route of preparation of the two composites with PDMS and respectively PVDF matrix, with tailored deposition on specific substrates for microelectronic use (e.g. indium-tin-oxide ITO/glass, Si/Pt, polyethylene terephthalate PET), along with an extensive comparation of their dielectric features, a consistent comparison of the influence of polymer matrix upon the piezoelectric features, and a demonstration of direct use for microelectronic applications of the composites of BT with PDMS. An interesting effect is observed around 100 kHz domain, determined by the activity and architecture of BT particles mainly for the BT-PDMS composites, which induce an additional ionic-dipolar conjugated polarization, as a displacement due to the balance between the resonance and anti-resonance frequency. Such phenomena explain the potential use of such composites as resonators/filters, and BT-PDMS composites should be further investigated for tailored applications in radiofrequency electronic field. We can appreciate that superior piezoelectric features are offered by the composites of BT with PDMS, comparing to the composites with PVDF, which means that the composites of BT with PDMS were worth to study, leading to more versatile variants of electronic characteristics and with superior values.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Todor, Razvan Fluieras, Dan Florin Bonta, I. Olariu, I. Lile, Otilia Lavinia Stana, R. Popovici, Sergiu Andrei Todor, Daniela Domocos, Ana Maria Matichescu
Among the properties of materials for direct coronal restorations, water absorption is particularly important, influencing the mechanical properties, color and adhesion of the restorations made.The aim of this study was to compare the water absorption of six dental restorative materials, two composite, two compomers and two glass ionomers. Water absorption was determined on disk samples. 30 discs were prepared, 5 of each studied material, with a diameter of 15 mm and a thickness of 1 mm. The water absorption test was carried out based on the ISO 4049 specification. The composites and compomers showed a water absorption within the standard limits (40 �g/mm3). Glass ionomers show high water absorption, therefore to be used as coronal restorative materials they need to be coated with a protective varnish.
{"title":"In vitro Study on Water Absorption of Dental Restorative Materials","authors":"L. Todor, Razvan Fluieras, Dan Florin Bonta, I. Olariu, I. Lile, Otilia Lavinia Stana, R. Popovici, Sergiu Andrei Todor, Daniela Domocos, Ana Maria Matichescu","doi":"10.37358/mp.23.4.5693","DOIUrl":"https://doi.org/10.37358/mp.23.4.5693","url":null,"abstract":"\u0000Among the properties of materials for direct coronal restorations, water absorption is particularly important, influencing the mechanical properties, color and adhesion of the restorations made.The aim of this study was to compare the water absorption of six dental restorative materials, two composite, two compomers and two glass ionomers. Water absorption was determined on disk samples. 30 discs were prepared, 5 of each studied material, with a diameter of 15 mm and a thickness of 1 mm. The water absorption test was carried out based on the ISO 4049 specification. The composites and compomers showed a water absorption within the standard limits (40 �g/mm3). Glass ionomers show high water absorption, therefore to be used as coronal restorative materials they need to be coated with a protective varnish.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In this study, hybrid composite material composed of Poly Lactic Acid (PLA) and Cassia Auriculata (CA) were fabricated and the mechanical properties were evaluated to assess the impact of bio filler loading in the bio polymer (PLA) matrix. In order to fabricate the composite specimens, the CA bio filler was added to the PLA matrix in proportions of 10%, 20%, 30%, 40% and 50% by volume. In line with ASTM specifications, experiments were conducted to establish how the hybrid bio matrix, which was composed of both PLA and CA influenced the composite s mechanical characteristics. The test results indicated that adding 30 percent CA to PLA enhanced the material s mechanical, dynamic mechanical analysis, thermogravimetric properties. The composite composition with better properties was considered for further fabrication of a colposcopy fixture, the component was fabricated using additive manufacturing methodology.
本研究制作了由聚乳酸（PLA）和决明子（CA）组成的混合复合材料，并对其机械性能进行了评估，以评估生物填料在生物聚合物（PLA）基体中的添加量对其性能的影响。为了制作复合材料试样，在聚乳酸基体中按体积比 10%、20%、30%、40% 和 50%的比例添加了 CA 生物填料。根据美国材料与试验协会（ASTM）的规范，我们进行了实验，以确定由聚乳酸和 CA 组成的混合生物基质如何影响复合材料的机械特性。测试结果表明，在聚乳酸中添加 30% 的 CA 可提高材料的机械、动态力学分析和热重特性。性能更佳的复合材料被考虑用于进一步制造阴道镜夹具，该部件采用添加制造方法制造。
{"title":"Mechanical Properties, DMA and Structural Analysis of Cassia Auriculata/PLA Blended Hybrid bio Matrix Composite","authors":"Sengalani Perumal Srinivasan, Raghavendran Giri, Vajjiram Santhanam, Paulraj Prabhu","doi":"10.37358/mp.23.4.5689","DOIUrl":"https://doi.org/10.37358/mp.23.4.5689","url":null,"abstract":"\u0000In this study, hybrid composite material composed of Poly Lactic Acid (PLA) and Cassia Auriculata (CA) were fabricated and the mechanical properties were evaluated to assess the impact of bio filler loading in the bio polymer (PLA) matrix. In order to fabricate the composite specimens, the CA bio filler was added to the PLA matrix in proportions of 10%, 20%, 30%, 40% and 50% by volume. In line with ASTM specifications, experiments were conducted to establish how the hybrid bio matrix, which was composed of both PLA and CA influenced the composite s mechanical characteristics. The test results indicated that adding 30 percent CA to PLA enhanced the material s mechanical, dynamic mechanical analysis, thermogravimetric properties. The composite composition with better properties was considered for further fabrication of a colposcopy fixture, the component was fabricated using additive manufacturing methodology.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This article examines the impact of surface treatment of glass fibers on the strength of a composite material with an unsaturated polyester polymer matrix reinforced with glass fibers. The strength tests conducted include tensile, bending, and impact strength tests, as well as weight loss measurements. The research was conducted in two stages: in the first stage, the time was kept constant while the fibers were treated with varying concentrations of an alkaline NaOH solution; in the second stage, the concentration was fixed and the variable parameter was the treatment time. The results of the study indicate that surface treatment of glass fibers significantly improves their adhesion to the matrix materials, resulting in improved strength test results for the composite samples. The impact resistance, bending resistance, and tensile strength values all increased compared to the reference samples. However, certain changes in the individual parameters of fiber processing led to a slight decrease in tensile strength when it fell below the reference values. Additionally, it was observed that as the concentration of the solution and treatment time increased, the weight of the fibers decreased.
{"title":"The Study of the Glass Fiber Surface Treatment Effect on the Base Strength Characteristics of the Composite Material","authors":"Imad Rezakalla Antypas, A. Dyachenko","doi":"10.37358/mp.23.4.5695","DOIUrl":"https://doi.org/10.37358/mp.23.4.5695","url":null,"abstract":"\u0000This article examines the impact of surface treatment of glass fibers on the strength of a composite material with an unsaturated polyester polymer matrix reinforced with glass fibers. The strength tests conducted include tensile, bending, and impact strength tests, as well as weight loss measurements. The research was conducted in two stages: in the first stage, the time was kept constant while the fibers were treated with varying concentrations of an alkaline NaOH solution; in the second stage, the concentration was fixed and the variable parameter was the treatment time. The results of the study indicate that surface treatment of glass fibers significantly improves their adhesion to the matrix materials, resulting in improved strength test results for the composite samples. The impact resistance, bending resistance, and tensile strength values all increased compared to the reference samples. However, certain changes in the individual parameters of fiber processing led to a slight decrease in tensile strength when it fell below the reference values. Additionally, it was observed that as the concentration of the solution and treatment time increased, the weight of the fibers decreased.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139450061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Andreea Ghenciu (Bolintineanu), Sorin Lucian Bolintineanu, F. Borcan, D. Zăhoi
Simvastatin, a lipid-lowering drug from the statins group, is used in various dyslipidemias. It appears like a very useful medication to decrease the level of total cholesterol, of the low-density-lipids and triglycerides from blood, but it is well-known that the administration of statins have serious side effects, like muscle pain and weakness that can lead to kidney damage, rash on the skin and inflammation of the joints and of the blood vessels, shortness of breath, inflammation of the liver, dark urine, anemia, memory and sleep disorders, and problems in performing the sexual act. The main aims of this research were to obtain and to characterize a polymer carrier used for the transmembrane transfer of simvastatin. Hepatic arterial variations are common knowledge and it has been studied that these types of arteries have a narrower endoluminal diameter, therefore the patients may be prone to develop atherosclerosis more rapid that the ones with standard hepatic arterial patterns. The samples based on polyurethane structures with and respectively without the active agent were synthesized and characterized by measurements of pH, encapsulation efficacy, cumulative drug release in a simulated body fluid, scanning electron microscopy, Zetasizer measurements, thermal stability, cytotoxicity assay, and non-invasive skin irritation assessment. The results indicate the obtaining of heterogenous polyurethane structures with mean sizes between 80-440 nm and neutral pH, that have a good stability against the agglomeration tendency and a prolonged release rate. The results on structures cytotoxicity and their non-irritative potential are important clues that can be used in further clinical investigations.
{"title":"Surface-modified Polyurethane Structures Used as a Carrier for Simvastatin for the Possible Treatment of Atherosclerosis in Patients with Hepatic Arterial Variations","authors":"Laura Andreea Ghenciu (Bolintineanu), Sorin Lucian Bolintineanu, F. Borcan, D. Zăhoi","doi":"10.37358/mp.23.4.5690","DOIUrl":"https://doi.org/10.37358/mp.23.4.5690","url":null,"abstract":"\u0000Simvastatin, a lipid-lowering drug from the statins group, is used in various dyslipidemias. It appears like a very useful medication to decrease the level of total cholesterol, of the low-density-lipids and triglycerides from blood, but it is well-known that the administration of statins have serious side effects, like muscle pain and weakness that can lead to kidney damage, rash on the skin and inflammation of the joints and of the blood vessels, shortness of breath, inflammation of the liver, dark urine, anemia, memory and sleep disorders, and problems in performing the sexual act. The main aims of this research were to obtain and to characterize a polymer carrier used for the transmembrane transfer of simvastatin. Hepatic arterial variations are common knowledge and it has been studied that these types of arteries have a narrower endoluminal diameter, therefore the patients may be prone to develop atherosclerosis more rapid that the ones with standard hepatic arterial patterns. The samples based on polyurethane structures with and respectively without the active agent were synthesized and characterized by measurements of pH, encapsulation efficacy, cumulative drug release in a simulated body fluid, scanning electron microscopy, Zetasizer measurements, thermal stability, cytotoxicity assay, and non-invasive skin irritation assessment. The results indicate the obtaining of heterogenous polyurethane structures with mean sizes between 80-440 nm and neutral pH, that have a good stability against the agglomeration tendency and a prolonged release rate. The results on structures cytotoxicity and their non-irritative potential are important clues that can be used in further clinical investigations.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Recent progress in Material Extrusion-based Additive Manufacturing (MEX) has introduced active foaming agents in filaments composition, thus allowing for the tuning, by various process parameters, the hardness and the mechanical behavior of 3D-printed parts. In case of thermoplastic polyurethane (TPU) filaments, these advances significantly broaden the range of applications, particularly in the domains of comfort and orthotics (wrist-hand orthoses, insoles), offering the dual benefits of design flexibility inherent in MEX and the comfort of lightweight and customizable structures. However, the field is still in its early stages, with only a limited number of research efforts dedicated to characterizing these novel materials. In this context, this study is focused on determining the influence of printing temperature (190�C, 220�C, 240�C), infill density (25%, 35%, 45%) and infill pattern (honeycomb, gyroid) over the hardness of cylindrical specimens made of Colorfabb varioShore TPU. A comprehensive methodology of calibration is also presented as mandatory for obtaining good quality and accurate products by establishing correlations between flow rate and printing temperatures. The findings showed that the printing temperature is the most relevant factor impacting the hardness of varioShore TPU prints. At a printing temperature of 190�C, which corresponds to less foamed prints, the honeycomb infill yielded higher hardness compared to the gyroid infill, but the difference was not significant. Also, at 220�C and 240�C, the mean values of hardness remain relatively consistent, regardless of infill density and pattern.
{"title":"Effect of Process Parameters on the Hardness of 3D-printed Thermoplastic Polyurethane that Includes Foaming Agent","authors":"Mariana Cristiana Iacob, Diana Popescu, F. Baciu","doi":"10.37358/mp.23.4.5694","DOIUrl":"https://doi.org/10.37358/mp.23.4.5694","url":null,"abstract":"\u0000Recent progress in Material Extrusion-based Additive Manufacturing (MEX) has introduced active foaming agents in filaments composition, thus allowing for the tuning, by various process parameters, the hardness and the mechanical behavior of 3D-printed parts. In case of thermoplastic polyurethane (TPU) filaments, these advances significantly broaden the range of applications, particularly in the domains of comfort and orthotics (wrist-hand orthoses, insoles), offering the dual benefits of design flexibility inherent in MEX and the comfort of lightweight and customizable structures. However, the field is still in its early stages, with only a limited number of research efforts dedicated to characterizing these novel materials. In this context, this study is focused on determining the influence of printing temperature (190�C, 220�C, 240�C), infill density (25%, 35%, 45%) and infill pattern (honeycomb, gyroid) over the hardness of cylindrical specimens made of Colorfabb varioShore TPU. A comprehensive methodology of calibration is also presented as mandatory for obtaining good quality and accurate products by establishing correlations between flow rate and printing temperatures. The findings showed that the printing temperature is the most relevant factor impacting the hardness of varioShore TPU prints. At a printing temperature of 190�C, which corresponds to less foamed prints, the honeycomb infill yielded higher hardness compared to the gyroid infill, but the difference was not significant. Also, at 220�C and 240�C, the mean values of hardness remain relatively consistent, regardless of infill density and pattern.\u0000","PeriodicalId":18360,"journal":{"name":"Materiale Plastice","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139449755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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