Polymer alloying is particularly important due to the possibility of choosing a wide range of materials and the ability to design a product with desired properties. In case of incompatibility between the components, the resulting alloy cannot meet the set of desired properties and shows poor performance. In this research, alloys of polyvinyl chloride and polylactic acid were prepared in an internal mixer and nanoclay and maleic anhydride-grafted styrene-ethylene/butylene-styrene (SEBS-g-MAH) compatibilizer were used to improve the properties. In order to investigate the morphology and phase distribution of polylactic acid, scanning electron microscope images were taken. Tensile and dynamic mechanical thermal analysis tests were performed to evaluate the properties of the samples. The scanning electron microscope test images show the improvement of system uniformity by adding compatibilizer to the alloy. Adding nanoclay to the alloy increased the storage modulus and uniformity of the system. An increase in glass transition temperature and storage modulus was observed in the samples containing compatibilizer, and the uniformity of the system was also improved. The tensile test results showed that by adding nanoclay up to 3 % by weight, the tensile strength and Young′s modulus increase. Addition of compatibilizer up to 5 % by weight increased the physical and mechanical properties.