The aim of the study is the assessment of the food security status and its association with some risk factors of chronic obesity-related diseases in Ardabil-Iran population. METHODS: This cross-sectional study was done between 500 adults of Ardabil that were selected by random sampling from Persian cohort study participants, in January 2019. Food insecurity of study participants was measured using the United States Department of Agriculture 18-item questionnaire. Some risk factors of chronic diseases including fasting blood glucose, lipid profile, liver enzymes, and dietary information were measured on the day of the interview. To assess the association between variables the correlation and linear regression tests were used. RESULTS: Forty-eight and six percent of the study participants were food secure and 51.4% were in food insecurity status. There were a significant difference in weight, blood glucose, blood pressure, and serum triglyceride levels between the food security status groups (P < 0.05). The food insecurity score had significant association with participants, weight (p = 0.005,β= 1.66), serum triglycerides (p = 0.022,β= 0.027), body mass index (p = 0.003,β= 0.645) and fasting blood sugar (p = 0.0001,β= 0.664). CONCLUSION: About half of the participants were in food insecurity status. Food insecurity status can be associated with obesity and some risk factors of chronic obesity-related diseases. This problem requires main food policies to reduce food insecurity in the community.
{"title":"Food security association with some risk factors of obesity-related diseases in Ardabil-Iran population","authors":"M. Mohajeri, Reza Mohajery","doi":"10.3233/mnm-211522","DOIUrl":"https://doi.org/10.3233/mnm-211522","url":null,"abstract":"The aim of the study is the assessment of the food security status and its association with some risk factors of chronic obesity-related diseases in Ardabil-Iran population. METHODS: This cross-sectional study was done between 500 adults of Ardabil that were selected by random sampling from Persian cohort study participants, in January 2019. Food insecurity of study participants was measured using the United States Department of Agriculture 18-item questionnaire. Some risk factors of chronic diseases including fasting blood glucose, lipid profile, liver enzymes, and dietary information were measured on the day of the interview. To assess the association between variables the correlation and linear regression tests were used. RESULTS: Forty-eight and six percent of the study participants were food secure and 51.4% were in food insecurity status. There were a significant difference in weight, blood glucose, blood pressure, and serum triglyceride levels between the food security status groups (P < 0.05). The food insecurity score had significant association with participants, weight (p = 0.005,β= 1.66), serum triglycerides (p = 0.022,β= 0.027), body mass index (p = 0.003,β= 0.645) and fasting blood sugar (p = 0.0001,β= 0.664). CONCLUSION: About half of the participants were in food insecurity status. Food insecurity status can be associated with obesity and some risk factors of chronic obesity-related diseases. This problem requires main food policies to reduce food insecurity in the community.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44017692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Boutahar, K. Kaoutar, A. Chetoui, Abdessalam El Kardoudi, S. Ihbour, M. Najimi, F. Chigr
BACKGROUND: Adolescent obesity has become a pressing public health issue in Morocco. Along with the increased prevalence of obesity, body weight misperceptions have also increased among adolescents, which may reduce the effectiveness of intervention programs. The main study objective was to establish the relationship between body image perception, anthropometric status and their associated factors among a sample of Moroccan adolescents. METHODS: A cross-sectional school-based survey was conducted during 2018, involving 250 adolescents from Morocco. Data on sociodemographic information, anthropometric characteristics, and weight perception were collected and reported as the means and proportions. Statistical analysis was carried out using Statistical Package for Social Sciences version 19.0 software. RESULTS: The prevalence of overweight and obesity in our study reached 12.8% and 4.8%, respectively. Misperception of body weight compared to body mass index (BMI) was found in 50.4% of young adolescents (χ2 = 54.05; p < 0.001), and dissatisfaction computed by the Feel minus Ideal Discrepancy (FID) index reached 46% with no difference between the sexes (χ2 = 2.55; p > 0.05). The Feel weight status minus Actual weight status Inconsistency (FAI) index was used to determine whether the subjects’ perception of their weight was realistic. The results showed that both sexes tended to underestimate their weight. Only 68.2% of overweight/obese participants reported trying to lose weight (χ2 = 39.74; p < 0.001), while this number increased to 94.7% when the intention to lose weight was related to perceived body image (χ2 = 86.09; p < 0.001). CONCLUSIONS: The results of this study reveal that a mismatch exists between the perception of body weight and actual BMI in adolescents, with a tendency toward underestimation, affirming the early effect of social norms and the vulnerability to sociocultural influences of individuals in this age category. Future interventions and educational programs are thus required to prevent overweight and obesity and to address the mismatch between adolescents’ weight status and their perceived weight.
{"title":"Nutritional status and body image perception in a group of moroccan adolescents","authors":"K. Boutahar, K. Kaoutar, A. Chetoui, Abdessalam El Kardoudi, S. Ihbour, M. Najimi, F. Chigr","doi":"10.3233/mnm-211519","DOIUrl":"https://doi.org/10.3233/mnm-211519","url":null,"abstract":"BACKGROUND: Adolescent obesity has become a pressing public health issue in Morocco. Along with the increased prevalence of obesity, body weight misperceptions have also increased among adolescents, which may reduce the effectiveness of intervention programs. The main study objective was to establish the relationship between body image perception, anthropometric status and their associated factors among a sample of Moroccan adolescents. METHODS: A cross-sectional school-based survey was conducted during 2018, involving 250 adolescents from Morocco. Data on sociodemographic information, anthropometric characteristics, and weight perception were collected and reported as the means and proportions. Statistical analysis was carried out using Statistical Package for Social Sciences version 19.0 software. RESULTS: The prevalence of overweight and obesity in our study reached 12.8% and 4.8%, respectively. Misperception of body weight compared to body mass index (BMI) was found in 50.4% of young adolescents (χ2 = 54.05; p < 0.001), and dissatisfaction computed by the Feel minus Ideal Discrepancy (FID) index reached 46% with no difference between the sexes (χ2 = 2.55; p > 0.05). The Feel weight status minus Actual weight status Inconsistency (FAI) index was used to determine whether the subjects’ perception of their weight was realistic. The results showed that both sexes tended to underestimate their weight. Only 68.2% of overweight/obese participants reported trying to lose weight (χ2 = 39.74; p < 0.001), while this number increased to 94.7% when the intention to lose weight was related to perceived body image (χ2 = 86.09; p < 0.001). CONCLUSIONS: The results of this study reveal that a mismatch exists between the perception of body weight and actual BMI in adolescents, with a tendency toward underestimation, affirming the early effect of social norms and the vulnerability to sociocultural influences of individuals in this age category. Future interventions and educational programs are thus required to prevent overweight and obesity and to address the mismatch between adolescents’ weight status and their perceived weight.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42264644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Koçyiğit, Elif Adanur Uzunlar, Ş. Özer, Hazal Küçükkaraca Zakkour, G. Akbulut
BACKGROUND: The term intuitive eating is a new concept that has emerged in recent years. It is a way of eating that is based on responding to the body’s natural signals of hunger and satiety. OBJECTIVE: The study was conducted to evaluate the relationship between intuitive eating and eating disorders and body image perception in young adult women. METHODS: The study was conducted with 400 women aged 19–35 years. The data were collected with the Figure Rating Scale, the Intuitive Eating Scale-2 (IES-2), and the Eating Attitude Test-26. RESULTS: The mean body mass index was significantly higher in individuals who misperceived their body image. While 51.4% of the participants with normal eating behavior had appropriate body image perception, 38.8% of the participants with abnormal eating behavior had appropriate body image perception. The IES-2 total score was significantly lower in women with abnormal eating behavior and overweight/obese women. CONCLUSIONS: Our findings showed that intuitive eating is negatively associated with abnormal eating behavior and obesity in young adult women and that women with low intuitive eating inclinations misperceived their body image.
{"title":"The relationship between intuitive eating, eating disorders, and body image perceptions in young adult women","authors":"E. Koçyiğit, Elif Adanur Uzunlar, Ş. Özer, Hazal Küçükkaraca Zakkour, G. Akbulut","doi":"10.3233/mnm-211583","DOIUrl":"https://doi.org/10.3233/mnm-211583","url":null,"abstract":"BACKGROUND: The term intuitive eating is a new concept that has emerged in recent years. It is a way of eating that is based on responding to the body’s natural signals of hunger and satiety. OBJECTIVE: The study was conducted to evaluate the relationship between intuitive eating and eating disorders and body image perception in young adult women. METHODS: The study was conducted with 400 women aged 19–35 years. The data were collected with the Figure Rating Scale, the Intuitive Eating Scale-2 (IES-2), and the Eating Attitude Test-26. RESULTS: The mean body mass index was significantly higher in individuals who misperceived their body image. While 51.4% of the participants with normal eating behavior had appropriate body image perception, 38.8% of the participants with abnormal eating behavior had appropriate body image perception. The IES-2 total score was significantly lower in women with abnormal eating behavior and overweight/obese women. CONCLUSIONS: Our findings showed that intuitive eating is negatively associated with abnormal eating behavior and obesity in young adult women and that women with low intuitive eating inclinations misperceived their body image.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44404033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Hamman, S. Garba, T. Jacks, J. V. Zirahei, N. Dibal, M. Attah
BACKGROUND: Chronic hyperglycemia results in decrease glucose metabolism leading to nephropathy, hepatotoxicity and neuropathy. Diabetic complications are regarded globally as one of the leading cause of disability and mortality. OBJECTIVE: The study aims to evaluate the role of Zingiber officinale (ZO) on diabetic nephropathy and hepatotoxicity in rats. METHODS: Thirty diabetic rats and six non-diabetic rats were distributed into six groups (n = 6). Group 1 & 2 (nondiabetic and diabetic) received distilled water at 1 ml/kg. Groups 3–5 received (12.5, 25& 50) mg/kg of ZO respectively while group 6 received 100 mg/kg metformin. All treatments lasted for 28 days and rats were euthanized on day 29. Biochemical parameters, kidney and liver histology were evaluated. RESULTS: No significant change (P > 0.05) was noticed in blood glucose and creatinine levels of diabetic rats treated with 25 mg/kg ZO compared to control. The liver of 25 mg/kg ZO treated diabetic rats showed mild distortion of hepatocytes while kidneys of ZO treated diabetic rats showed mild distortion of renal tubules with few collagen deposits and intact Bowman’s capsule. CONCLUSIONS: ZO ameliorates diabetic complications by regulating biochemical parameters and preventing renal tubules and hepatocytes damage in rats.
{"title":"Zingiber officinale ameliorates diabetic nephropathy and hepatotoxicity in rats by preventing tissue injury and controlling liver/kidney function","authors":"L. Hamman, S. Garba, T. Jacks, J. V. Zirahei, N. Dibal, M. Attah","doi":"10.3233/mnm-211557","DOIUrl":"https://doi.org/10.3233/mnm-211557","url":null,"abstract":"BACKGROUND: Chronic hyperglycemia results in decrease glucose metabolism leading to nephropathy, hepatotoxicity and neuropathy. Diabetic complications are regarded globally as one of the leading cause of disability and mortality. OBJECTIVE: The study aims to evaluate the role of Zingiber officinale (ZO) on diabetic nephropathy and hepatotoxicity in rats. METHODS: Thirty diabetic rats and six non-diabetic rats were distributed into six groups (n = 6). Group 1 & 2 (nondiabetic and diabetic) received distilled water at 1 ml/kg. Groups 3–5 received (12.5, 25& 50) mg/kg of ZO respectively while group 6 received 100 mg/kg metformin. All treatments lasted for 28 days and rats were euthanized on day 29. Biochemical parameters, kidney and liver histology were evaluated. RESULTS: No significant change (P > 0.05) was noticed in blood glucose and creatinine levels of diabetic rats treated with 25 mg/kg ZO compared to control. The liver of 25 mg/kg ZO treated diabetic rats showed mild distortion of hepatocytes while kidneys of ZO treated diabetic rats showed mild distortion of renal tubules with few collagen deposits and intact Bowman’s capsule. CONCLUSIONS: ZO ameliorates diabetic complications by regulating biochemical parameters and preventing renal tubules and hepatocytes damage in rats.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":"1 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70143245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND/AIM: Hypertension is a global public health problem and a leading cause of cardiovascular morbidity and mortality. In this paper, we study the effect of olive cake (OC) on blood pressure, endothelial dysfunction, redox status and vascular remodeling in dexamethasone-induced hypertensive (HT) rats. METHODS: HT rats were divided into two groups fed standard diet supplemented (HT-OC) or not (HT) with OC at 7.5% for 28 days. A control (C) was submitted to standard diet for the same experimental period. RESULTS: Systolic, diastolic and mean blood pressures were higher in the HT vs C and decreased in HT-OC vs HT. Aortic nitric oxide value was decreased in the HT vs the C and increased in HT-OC vs HT. Aortic lipid and protein oxidation products were higher in the HT than C and lower in the HT-OC vs HT. Aortic antioxidant enzymes activities were reduced in HT than control and increased in the HT-OC vs HT. The aortic wall thickness, medial cross-sectional area, media to lumen ratio and the number of VSMCs were higher in the HT and the OC has regressed vascular redemptions. CONCLUSION: In hypertensive rats, OC may alleviate blood pressure and arterial remodeling by suppressing oxidative stress, increasing antioxidant activity, improving endothelial function, preventing smooth muscle proliferation and thickening of the tunica media.
{"title":"Olive cake reduces blood pressure, oxidative stress, aortic endothelial dysfunction and vascular remodeling, in dexamethasone-induced hypertensive rats","authors":"Mansourou Samba Garba, S. Bouderbala","doi":"10.3233/mnm-220001","DOIUrl":"https://doi.org/10.3233/mnm-220001","url":null,"abstract":"BACKGROUND/AIM: Hypertension is a global public health problem and a leading cause of cardiovascular morbidity and mortality. In this paper, we study the effect of olive cake (OC) on blood pressure, endothelial dysfunction, redox status and vascular remodeling in dexamethasone-induced hypertensive (HT) rats. METHODS: HT rats were divided into two groups fed standard diet supplemented (HT-OC) or not (HT) with OC at 7.5% for 28 days. A control (C) was submitted to standard diet for the same experimental period. RESULTS: Systolic, diastolic and mean blood pressures were higher in the HT vs C and decreased in HT-OC vs HT. Aortic nitric oxide value was decreased in the HT vs the C and increased in HT-OC vs HT. Aortic lipid and protein oxidation products were higher in the HT than C and lower in the HT-OC vs HT. Aortic antioxidant enzymes activities were reduced in HT than control and increased in the HT-OC vs HT. The aortic wall thickness, medial cross-sectional area, media to lumen ratio and the number of VSMCs were higher in the HT and the OC has regressed vascular redemptions. CONCLUSION: In hypertensive rats, OC may alleviate blood pressure and arterial remodeling by suppressing oxidative stress, increasing antioxidant activity, improving endothelial function, preventing smooth muscle proliferation and thickening of the tunica media.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":"1 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41470066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Having comprehensive and validated tools to effectively measure levels of Health Literacy (HL) in the general population is of great importance, since HL levels appear to be an crucial determinant of the population’s overall health. OBJECTIVE: The aim of the study was to validate the Greek version of the HLS_EU_Q16 questionnaire. METHODS: A total of 496 participants (81.8% women) participated in a self-administrated online, cross-sectional survey. The participants had to concurrently complete the Greek Version of HLS_EU_Q16 and the New Vital Sign (NVS). Certain socioeconomic and anthropometric characteristics also assessed. For test-retest reliability, 149 of the participants completed the questionnaire twice within a 15-day period. Principal Component Analysis, Cronbach’s a Spearman’s rho were used. RESULTS: All 3 factors assessed by the tool: “Health Care”, “Disease Prevention” and “Health Promotion”, had eigenvalues greater than 1. The Cronbach’s a was 0.884, for the total score of the HLS_EU_Q16 and 0.790, 0.710 and 0.800, for the above 3 subscales, respectively. Finally, test–retest reliability, after 15 days for the HLS_EU_Q16, resulted in Spearman’s correlation coefficient of r = 0.628 (p < 0.0001) which show a high correlation. CONCLUSIONS: Results indicate that the HLS_EU_Q16 is a reliable and valid tool for assessing HL in the Greek population.
{"title":"Validity and reliability of the european health literacy survey questionnaire (HLS_EU_Q16) in the greek language","authors":"M. Michou, V. Costarelli","doi":"10.3233/mnm-211538","DOIUrl":"https://doi.org/10.3233/mnm-211538","url":null,"abstract":"BACKGROUND: Having comprehensive and validated tools to effectively measure levels of Health Literacy (HL) in the general population is of great importance, since HL levels appear to be an crucial determinant of the population’s overall health. OBJECTIVE: The aim of the study was to validate the Greek version of the HLS_EU_Q16 questionnaire. METHODS: A total of 496 participants (81.8% women) participated in a self-administrated online, cross-sectional survey. The participants had to concurrently complete the Greek Version of HLS_EU_Q16 and the New Vital Sign (NVS). Certain socioeconomic and anthropometric characteristics also assessed. For test-retest reliability, 149 of the participants completed the questionnaire twice within a 15-day period. Principal Component Analysis, Cronbach’s a Spearman’s rho were used. RESULTS: All 3 factors assessed by the tool: “Health Care”, “Disease Prevention” and “Health Promotion”, had eigenvalues greater than 1. The Cronbach’s a was 0.884, for the total score of the HLS_EU_Q16 and 0.790, 0.710 and 0.800, for the above 3 subscales, respectively. Finally, test–retest reliability, after 15 days for the HLS_EU_Q16, resulted in Spearman’s correlation coefficient of r = 0.628 (p < 0.0001) which show a high correlation. CONCLUSIONS: Results indicate that the HLS_EU_Q16 is a reliable and valid tool for assessing HL in the Greek population.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45947898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dwi Rahmaisyah, Widya Wasityastuti, Fajar Dwi Astarini, D. I. Widasari
BACKGROUND: Inflammatory Bowel Disease (IBD) causes gastrointestinal tract dysregulation and triggers inflammation. Severe inflammatory events often lead to leukocyte infiltration. Yacon is known to have anti-inflammatory properties, making it a potential alternative treatment for colitis. AIMS: To investigate colonic Interleukin-23 (IL-23) level and leukocyte infiltration profile in 2,4,6-Trinitrobenzene Sulfonic Acid (TNBS)-induced colitis mouse model treated with yacon syrup powder. METHODS: Thirty male BALB/c mice (5 weeks old, body weight: 30.02±1.28 g) were randomly divided into 6 groups (K1-K6). Intra-rectal administration of TNBS was performed to K2-K6 to make the colitis model. K4-K6 were given yacon syrup powder daily for 14 days with the dose of 0.165, 0.331, and 0.662 g/30 g body weight (BW) respectively. IL-23 levels of colonic tissue were measured using ELISA. Leukocyte infiltration profile was calculated through microscopic observation of histology slides and presented in percentage and degree. RESULTS: Significantly different IL-23 levels were observed among the groups (P < 0.001). The percentage and degree of leukocyte infiltration in yacon-treated groups showed a significant decrease compared to colitis groups (P < 0.001). CONCLUSION: Yacon syrup powder provides beneficial effects on colitis mice by lowering the IL-23 level and number of leukocytes at the inflammation site.
{"title":"Protective effects of yacon syrup powder on colonic interleukin-23 and leukocyte infiltration profile in TNBS-induced colitis mouse model","authors":"Dwi Rahmaisyah, Widya Wasityastuti, Fajar Dwi Astarini, D. I. Widasari","doi":"10.3233/mnm-211506","DOIUrl":"https://doi.org/10.3233/mnm-211506","url":null,"abstract":"BACKGROUND: Inflammatory Bowel Disease (IBD) causes gastrointestinal tract dysregulation and triggers inflammation. Severe inflammatory events often lead to leukocyte infiltration. Yacon is known to have anti-inflammatory properties, making it a potential alternative treatment for colitis. AIMS: To investigate colonic Interleukin-23 (IL-23) level and leukocyte infiltration profile in 2,4,6-Trinitrobenzene Sulfonic Acid (TNBS)-induced colitis mouse model treated with yacon syrup powder. METHODS: Thirty male BALB/c mice (5 weeks old, body weight: 30.02±1.28 g) were randomly divided into 6 groups (K1-K6). Intra-rectal administration of TNBS was performed to K2-K6 to make the colitis model. K4-K6 were given yacon syrup powder daily for 14 days with the dose of 0.165, 0.331, and 0.662 g/30 g body weight (BW) respectively. IL-23 levels of colonic tissue were measured using ELISA. Leukocyte infiltration profile was calculated through microscopic observation of histology slides and presented in percentage and degree. RESULTS: Significantly different IL-23 levels were observed among the groups (P < 0.001). The percentage and degree of leukocyte infiltration in yacon-treated groups showed a significant decrease compared to colitis groups (P < 0.001). CONCLUSION: Yacon syrup powder provides beneficial effects on colitis mice by lowering the IL-23 level and number of leukocytes at the inflammation site.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47720877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shilan Babamiri, Mansooreh Sadat Mojani Qomi, M. Shiehmorteza
BACKGROUND: There are growing interests in the use of medicinal mushrooms in controlling overweight and obesity. OBJECTIVE: The aim of the present study was to assess the effect of Lingzhi on anthropometric indices, fasting blood sugar, lipid profile and blood pressure of overweight individuals METHODS: This randomized double-blind clinical trial was performed on seventy-two overweight individuals (Body Mass Index (BMI) = 25–29.9 kg/m2) received 3 capsule Ganoderma Lucidum (each capsule containing 220 mg of whole powder and 30 mg of pure aqueous extract) daily or matching placebo for 6 weeks. Anthropometric indices, metabolic tests (fasting blood sugar (FBS) and serum lipid profile) and blood pressure were measured before and after treatment. RESULTS: Data analyses indicated that body weight and BMI were decreased after 6-week intervention (P < 0.05). The beneficial effect of supplementation was evident on some anthropometric indices. Changes in LDL-cholesterol were significantly different between two treatment and placebo groups (P < 0.05). FBS, other components of lipid profile and blood pressure did not significantly change by Lingzi treatment. CONCLUSIONS: Results showed that Ganoderma Lucidum might have some potential benefits on anthropometric indices and mild effects on lipid profile, but and there is no claim for weight lose function. Hence, further long-term studies are recommended.
{"title":"The Efficacy of Ganoderma lucidum in Overweight Individuals: A Randomized Placebo-controlled trial","authors":"Shilan Babamiri, Mansooreh Sadat Mojani Qomi, M. Shiehmorteza","doi":"10.3233/mnm-211533","DOIUrl":"https://doi.org/10.3233/mnm-211533","url":null,"abstract":"BACKGROUND: There are growing interests in the use of medicinal mushrooms in controlling overweight and obesity. OBJECTIVE: The aim of the present study was to assess the effect of Lingzhi on anthropometric indices, fasting blood sugar, lipid profile and blood pressure of overweight individuals METHODS: This randomized double-blind clinical trial was performed on seventy-two overweight individuals (Body Mass Index (BMI) = 25–29.9 kg/m2) received 3 capsule Ganoderma Lucidum (each capsule containing 220 mg of whole powder and 30 mg of pure aqueous extract) daily or matching placebo for 6 weeks. Anthropometric indices, metabolic tests (fasting blood sugar (FBS) and serum lipid profile) and blood pressure were measured before and after treatment. RESULTS: Data analyses indicated that body weight and BMI were decreased after 6-week intervention (P < 0.05). The beneficial effect of supplementation was evident on some anthropometric indices. Changes in LDL-cholesterol were significantly different between two treatment and placebo groups (P < 0.05). FBS, other components of lipid profile and blood pressure did not significantly change by Lingzi treatment. CONCLUSIONS: Results showed that Ganoderma Lucidum might have some potential benefits on anthropometric indices and mild effects on lipid profile, but and there is no claim for weight lose function. Hence, further long-term studies are recommended.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41938646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Foufa Bouabsa, Aicha Tir touil, M. A. Al Zoubi, Nadia Chelli, A. Léké, B. Meddah
BACKGROUND: Caffeine is a potent central and respiratory acting agent used in neonatology to treat apnea in premature newborns. OBJECTIVE: This study investigates the effects of caffeine orally administered to newborn rats on gastrointestinal permeability, bacterial translocation and different biochemical parameters. METHODS: Newborn rats were divided into different groups (N = 06). The treated newborn rats were orally administered with standard caffeine doses (12 mg/kg per day), and the control groups received a placebo. The animals were weighed daily until sacrifice. Blood samples, mesenteric lymph nodes (MLN) and organs were aseptically collected. Furthermore, different biochemical (D-Lactate) and oxidative stress biomarkers (MDA, CAT, SOD and GSH) levels were examined. Microbiological analyses were performed to assess microbiota alterations and bacterial translocation. RESULTS: Preliminary results showed that caffeine administration decreased the level of bacterial translocation over time. The treatment reduced plasma D-lactate levels (p < 0.05). Additionally, caffeine induced a disturbance in the concentrations of biochemical parameters and oxidative stress biomarkers. Indeed, liver enzymes (AST and ALT) were significantly (p < 0.05) risen after caffeine treatment. Glutathione (GSH) levels were significantly higher in caffeine treated groups (75.12±0.32; 51.98±1.12 U/mg; p < 0.05) comparing to control ones (40.82±0.25; 42.91±0.27 U/mg; p < 0.05) in the ileum and the colon, respectively. CONCLUSIONS: Thus, besides improving gastrointestinal permeability, our data show that caffeine has beneficial effects on the intestinal antioxidant system.
背景:咖啡因是一种有效的中枢和呼吸作用药物，用于新生儿治疗早产儿呼吸暂停。目的:研究新生大鼠口服咖啡因对胃肠通透性、细菌易位及不同生化指标的影响。方法:将新生大鼠分为不同组(N = 06)。接受治疗的新生大鼠口服标准剂量的咖啡因(每天12毫克/公斤)，对照组服用安慰剂。牲畜每天称重，直到献祭。无菌采集血液、肠系膜淋巴结(MLN)及脏器。此外，还检测了不同生化(d -乳酸)和氧化应激生物标志物(MDA、CAT、SOD和GSH)水平。进行微生物学分析以评估微生物群改变和细菌易位。结果:初步结果表明，随着时间的推移，咖啡因的服用降低了细菌易位的水平。治疗降低血浆d -乳酸水平(p < 0.05)。此外，咖啡因还会引起生化参数和氧化应激生物标志物浓度的紊乱。确实，咖啡因处理后肝酶(AST和ALT)显著(p < 0.05)升高。咖啡因处理组谷胱甘肽(GSH)水平显著升高(75.12±0.32;51.98±1.12 U /毫克;P < 0.05)，与对照组(40.82±0.25;42.91±0.27 U /毫克;P < 0.05)。结论:因此，我们的数据表明，除了改善胃肠道通透性外，咖啡因对肠道抗氧化系统也有有益的作用。
{"title":"Caffeine citrate effects on gastrointestinal permeability, bacterial translocation and biochemical parameters in newborn rats after long-term oral administration","authors":"Foufa Bouabsa, Aicha Tir touil, M. A. Al Zoubi, Nadia Chelli, A. Léké, B. Meddah","doi":"10.3233/mnm-211544","DOIUrl":"https://doi.org/10.3233/mnm-211544","url":null,"abstract":"BACKGROUND: Caffeine is a potent central and respiratory acting agent used in neonatology to treat apnea in premature newborns. OBJECTIVE: This study investigates the effects of caffeine orally administered to newborn rats on gastrointestinal permeability, bacterial translocation and different biochemical parameters. METHODS: Newborn rats were divided into different groups (N = 06). The treated newborn rats were orally administered with standard caffeine doses (12 mg/kg per day), and the control groups received a placebo. The animals were weighed daily until sacrifice. Blood samples, mesenteric lymph nodes (MLN) and organs were aseptically collected. Furthermore, different biochemical (D-Lactate) and oxidative stress biomarkers (MDA, CAT, SOD and GSH) levels were examined. Microbiological analyses were performed to assess microbiota alterations and bacterial translocation. RESULTS: Preliminary results showed that caffeine administration decreased the level of bacterial translocation over time. The treatment reduced plasma D-lactate levels (p < 0.05). Additionally, caffeine induced a disturbance in the concentrations of biochemical parameters and oxidative stress biomarkers. Indeed, liver enzymes (AST and ALT) were significantly (p < 0.05) risen after caffeine treatment. Glutathione (GSH) levels were significantly higher in caffeine treated groups (75.12±0.32; 51.98±1.12 U/mg; p < 0.05) comparing to control ones (40.82±0.25; 42.91±0.27 U/mg; p < 0.05) in the ileum and the colon, respectively. CONCLUSIONS: Thus, besides improving gastrointestinal permeability, our data show that caffeine has beneficial effects on the intestinal antioxidant system.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43345628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Taghizadeh, Wanich Suksatan, M. N. Shalaby, Mahdieh Abbasalizad-Farhangi, Ali Hojjati
BACKGROUND: This study aimed to evaluate the eating habits, physical activity, and body size perception by obesity status among 2–18 years old children in Iran. METHODS: This cross sectional study included 250 children and adolescents aged between 2 and 18. Participants’ anthropometric measurements were measured, adherence of Mediterranean Diet was evaluated by a questionnaire, the Mediterranean Diet Quality Index for children and adolescents (KIDMED), body satisfaction, and perception of body size. RESULTS: Mean age of subjects was 9.07±4.80 years, and 52.4% were girls. The KIDMED index score was 16.3% low, 54.3% moderate and 29.4% good. 72.7% of parents with overweight children and 36.4% with obese children, were perceived that their child was normal, and compared with 58.3% of overweight and 7.7% of obese participants perceived normal body size. There were no significant differences between physical activity in any weight status (p > 0.05) and between boys and girls in the KIDMED index and any of foods intake. There was a significant difference in mean differences of KIDMED index in boys in the four obesity statuses (P = 0.04), as well as in food consumption (P = 0.04), except for pulses in boys and girls. CONCLUSION: The percentage of obesity in boys is more compared to girls, the lowest KIDMED index score is for boys in the obesity group. Therefore, adopting healthier dietary habits and lifestyle in childhood is especially important for boys and also for girls.
{"title":"Life style, dietary patterns and physical activity in different obesity phenotypes of 2–18 years old children in Tabriz, Iran","authors":"S. Taghizadeh, Wanich Suksatan, M. N. Shalaby, Mahdieh Abbasalizad-Farhangi, Ali Hojjati","doi":"10.3233/mnm-211515","DOIUrl":"https://doi.org/10.3233/mnm-211515","url":null,"abstract":"BACKGROUND: This study aimed to evaluate the eating habits, physical activity, and body size perception by obesity status among 2–18 years old children in Iran. METHODS: This cross sectional study included 250 children and adolescents aged between 2 and 18. Participants’ anthropometric measurements were measured, adherence of Mediterranean Diet was evaluated by a questionnaire, the Mediterranean Diet Quality Index for children and adolescents (KIDMED), body satisfaction, and perception of body size. RESULTS: Mean age of subjects was 9.07±4.80 years, and 52.4% were girls. The KIDMED index score was 16.3% low, 54.3% moderate and 29.4% good. 72.7% of parents with overweight children and 36.4% with obese children, were perceived that their child was normal, and compared with 58.3% of overweight and 7.7% of obese participants perceived normal body size. There were no significant differences between physical activity in any weight status (p > 0.05) and between boys and girls in the KIDMED index and any of foods intake. There was a significant difference in mean differences of KIDMED index in boys in the four obesity statuses (P = 0.04), as well as in food consumption (P = 0.04), except for pulses in boys and girls. CONCLUSION: The percentage of obesity in boys is more compared to girls, the lowest KIDMED index score is for boys in the obesity group. Therefore, adopting healthier dietary habits and lifestyle in childhood is especially important for boys and also for girls.","PeriodicalId":18424,"journal":{"name":"Mediterranean Journal of Nutrition and Metabolism","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42019767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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