Therapeutic goals are reducing cardiovascular risk and and improving the circulation in the leg. Therapeutic options are surgical and endovascular procedures as well as conservative treatment. The main focus for patients with intermittent claudication is to enhance quality of life. Patients with critical ischemia however are threatened by the loss of an extremity. In these cases, a conservative treatment is usually not sufficient and circulation must be quickly ameliorated by an endovascular or surgical procedure.
{"title":"Peripheral artery disease: Introduction and conservative treatment.","authors":"Christine Espinola-Klein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Therapeutic goals are reducing cardiovascular risk and and improving the circulation in the leg. Therapeutic options are surgical and endovascular procedures as well as conservative treatment. The main focus for patients with intermittent claudication is to enhance quality of life. Patients with critical ischemia however are threatened by the loss of an extremity. In these cases, a conservative treatment is usually not sufficient and circulation must be quickly ameliorated by an endovascular or surgical procedure.</p>","PeriodicalId":18540,"journal":{"name":"Medizinische Monatsschrift fur Pharmazeuten","volume":"40 3","pages":"100-1"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 56 year old person presents with pain when walking. A peripheral artery disease in the iliacic vessels is diagnosed. Endovascular therapy results in a significant improvement. The following conservative treatment aims at reducing the cardiovascular risk. Especially stopping smoking turns out to be hard to achieve.
{"title":"A patient with peripheral artery disease.","authors":"Christine Espinola-Klein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 56 year old person presents with pain when walking. A peripheral artery disease in the iliacic vessels is diagnosed. Endovascular therapy results in a significant improvement. The following conservative treatment aims at reducing the cardiovascular risk. Especially stopping smoking turns out to be hard to achieve.</p>","PeriodicalId":18540,"journal":{"name":"Medizinische Monatsschrift fur Pharmazeuten","volume":"40 3","pages":"107-8"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syphilis is a chronic, multi-stage bacterial infection disease caused by the spirochate Treponema pallidum subsp. pallidum. In the primary stage of the disease, there is usually an ulcer formation (primary affection) in the genitoanal region. During the secondary stage, numerous, mainly skin-related disorders may appear. After a latency lasting up to several decades, a further stage can develop, in which the skin, the heart or the nervous system (neurosyphilis) is particularly affected. Applying an adequate antibacterial treatment regime with benzylpenicillin derivatives, syphilis can be cured in most cases at any stage of the disease. Exposure prophylaxis is most important in the prevention of syphilis.
{"title":"Syphilis – an update.","authors":"Ingo Stock","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Syphilis is a chronic, multi-stage bacterial infection disease caused by the spirochate Treponema pallidum subsp. pallidum. In the primary stage of the disease, there is usually an ulcer formation (primary affection) in the genitoanal region. During the secondary stage, numerous, mainly skin-related disorders may appear. After a latency lasting up to several decades, a further stage can develop, in which the skin, the heart or the nervous system (neurosyphilis) is particularly affected. Applying an adequate antibacterial treatment regime with benzylpenicillin derivatives, syphilis can be cured in most cases at any stage of the disease. Exposure prophylaxis is most important in the prevention of syphilis.</p>","PeriodicalId":18540,"journal":{"name":"Medizinische Monatsschrift fur Pharmazeuten","volume":"40 3","pages":"113-9"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36265457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peripheral artery disease is characterized by a limited blood circulation caused by stenosis or occlusion of peripheral arteries of the extremities. It is considered as a marker-disease of an advance atherosclerosis. Comorbidity with other manifestations of atherosclerosis like myocardial infarction or stroke is high.
{"title":"Peripheral artery disease: basic knowledge.","authors":"Christine Espinola-Klein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Peripheral artery disease is characterized by a limited blood circulation caused by stenosis or occlusion of peripheral arteries of the extremities. It is considered as a marker-disease of an advance atherosclerosis. Comorbidity with other manifestations of atherosclerosis like myocardial infarction or stroke is high.</p>","PeriodicalId":18540,"journal":{"name":"Medizinische Monatsschrift fur Pharmazeuten","volume":"40 3","pages":"95-7"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36266008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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