Pub Date : 2023-01-01DOI: 10.5455/medscience.2022.12.276
Erdem Ozden, A. Aybar
The navicular bone of the hand is the most frequently fractured bone among the carpal bones, and if not treated well, it may result in nonunion. Dorsal, volar open, or percutaneous approaches can be used in surgical treatment. We aimed to evaluate the results of internal fixation of scaphoid fractures with the dorsal mini-open technique. Patients with acute proximal and waist fractures who have been treated with cannulated compression screws with a dorsal mini open approach without grafting between 2015 and 2020 were included. Functional outcomes were analyzed with the DASH questionnaire and MAYO wrist performance scores and compared with the contralateral wrists. The mean age of the patients was 35.6 ±10.8 years (range 20-55), seven were proximal, and 13 were waist fractures. The mean time to surgery was 16±7.3 days (range 5-30) and the mean follow-up time was 47.5±20.2 weeks (range 20-84). The mean DASH score at the last follow-up was 5.9±3.3 points (range 2.5-11.7), and the Mayo wrist performance score was 96.8±5.2 points (range 85-100). In one proximal pole fracture, cracking occurred on the cartilage surface at the screw insertion site but consolidated without any additional intervention. The mean time to union was 8.5±1.2 weeks (range 7-11). Waist region fractures consolidated faster than proximal pole fractures (p=0.002). No significant difference was found between the fracture site and mid-term functional results. Complications like proximal cartilage fractures during the embedding of the screw head or prominence of the screw head can be avoided with the dorsal mini-open technique which is a safe and effective method.
{"title":"Internal fixation of acute scaphoid proximal pole & waist fractures using the dorsal mini open technique without bone grafting","authors":"Erdem Ozden, A. Aybar","doi":"10.5455/medscience.2022.12.276","DOIUrl":"https://doi.org/10.5455/medscience.2022.12.276","url":null,"abstract":"The navicular bone of the hand is the most frequently fractured bone among the carpal bones, and if not treated well, it may result in nonunion. Dorsal, volar open, or percutaneous approaches can be used in surgical treatment. We aimed to evaluate the results of internal fixation of scaphoid fractures with the dorsal mini-open technique. Patients with acute proximal and waist fractures who have been treated with cannulated compression screws with a dorsal mini open approach without grafting between 2015 and 2020 were included. Functional outcomes were analyzed with the DASH questionnaire and MAYO wrist performance scores and compared with the contralateral wrists. The mean age of the patients was 35.6 ±10.8 years (range 20-55), seven were proximal, and 13 were waist fractures. The mean time to surgery was 16±7.3 days (range 5-30) and the mean follow-up time was 47.5±20.2 weeks (range 20-84). The mean DASH score at the last follow-up was 5.9±3.3 points (range 2.5-11.7), and the Mayo wrist performance score was 96.8±5.2 points (range 85-100). In one proximal pole fracture, cracking occurred on the cartilage surface at the screw insertion site but consolidated without any additional intervention. The mean time to union was 8.5±1.2 weeks (range 7-11). Waist region fractures consolidated faster than proximal pole fractures (p=0.002). No significant difference was found between the fracture site and mid-term functional results. Complications like proximal cartilage fractures during the embedding of the screw head or prominence of the screw head can be avoided with the dorsal mini-open technique which is a safe and effective method.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83474084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.157
Bulent Halaclar
The main purpose of this study is to compare the efficacy of crystallized phenol and laser among treatment options in pilonidal sinus (SPS) discomfort in the sacrococcygeal region. A total of 190 patients were included in this retrospective archive research. Moreover, cases with missing or unclear data were not included in the study. Most patients were men [123 (64.3%) vs. 67 (35.3%); p<0.001]. There was no difference between the two groups in terms of age [31.37±8.92 vs. 31.20±8.85; p=0.92]. The majority of those who have applied laser were men [80 (80%) vs. 20 (20%); p<0.001]. It was determined that the majority of those who underwent laser were smokers [38 (67.9%) vs. 18 (32.1%); p<0.007]. The rate of phenol application was found to be slightly higher in females [47 (52.2%) vs. 43 (47.8%)]. In terms of comorbidity, there was no difference between the cases treated with phenol and laser [14 (40%) vs. 21 (60%); p=0.33]. There was no statistically significant difference in terms of the 12th month [84 (46.4%) vs. 97 (53.6%); p=0.312] or 24th month [82 (46.1%) vs. 92 (53.9%); p=0.167] recurrence rates for cases treated with phenol and laser. Moreover, there was no statistically significant difference between the two groups for cases who had reoperation [phenol: 13 (61.9%) vs. laser: 8 (38.1%); p=0.157]. Bleeding after the procedure was detected only in patients who underwent laser [0 (0.0%) vs. 6 (100%); p<0.03]. There was no difference in terms of infection in both groups [3 (50%) vs. 3 (50%); p=1.00]. With regard to the body mass index, no difference was found between the two groups that were treated with phenol or laser. However, regarding the visual analog scale (VAS), it was significantly lower in the phenol group [1.38±1.63 vs. 0.87±1.37; p=0.002]. In conclusion, while phenol is more advantageous in terms of pain and bleeding complications, laser treatment is preferred in men and smokers.
{"title":"Comparison of success rates of laser surgery and crystallized phenol treatment in pilonidal sinus treatment","authors":"Bulent Halaclar","doi":"10.5455/medscience.2023.08.157","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.157","url":null,"abstract":"The main purpose of this study is to compare the efficacy of crystallized phenol and laser among treatment options in pilonidal sinus (SPS) discomfort in the sacrococcygeal region. A total of 190 patients were included in this retrospective archive research. Moreover, cases with missing or unclear data were not included in the study. Most patients were men [123 (64.3%) vs. 67 (35.3%); p<0.001]. There was no difference between the two groups in terms of age [31.37±8.92 vs. 31.20±8.85; p=0.92]. The majority of those who have applied laser were men [80 (80%) vs. 20 (20%); p<0.001]. It was determined that the majority of those who underwent laser were smokers [38 (67.9%) vs. 18 (32.1%); p<0.007]. The rate of phenol application was found to be slightly higher in females [47 (52.2%) vs. 43 (47.8%)]. In terms of comorbidity, there was no difference between the cases treated with phenol and laser [14 (40%) vs. 21 (60%); p=0.33]. There was no statistically significant difference in terms of the 12th month [84 (46.4%) vs. 97 (53.6%); p=0.312] or 24th month [82 (46.1%) vs. 92 (53.9%); p=0.167] recurrence rates for cases treated with phenol and laser. Moreover, there was no statistically significant difference between the two groups for cases who had reoperation [phenol: 13 (61.9%) vs. laser: 8 (38.1%); p=0.157]. Bleeding after the procedure was detected only in patients who underwent laser [0 (0.0%) vs. 6 (100%); p<0.03]. There was no difference in terms of infection in both groups [3 (50%) vs. 3 (50%); p=1.00]. With regard to the body mass index, no difference was found between the two groups that were treated with phenol or laser. However, regarding the visual analog scale (VAS), it was significantly lower in the phenol group [1.38±1.63 vs. 0.87±1.37; p=0.002]. In conclusion, while phenol is more advantageous in terms of pain and bleeding complications, laser treatment is preferred in men and smokers.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136205102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.128
Nulufer Kilic
In the present study, the purpose was to analyze the applications made to the emergency department of a mental disease hospital in eastern Turkey. The applications to the mental health and diseases hospital emergency department between 01.01.2021 and 01.01.2022 were examined in the study. The demographic data and psychiatric diagnoses of the patients were recorded. The data of 3712 people who applied to the emergency department of the hospital were analyzed. A total of 37.98% of these patients were hospitalized. Men constituted the majority both in all applications and in patients who were hospitalized for observation and treatment. The most frequent application to the emergency department of the hospital was the patients brought by law enforcement officers with a rate of 26.64%. In patients who were hospitalized, schizophrenia and other psychotic disorders were in first place with a rate of 30.35%, bipolar disorder and mood disorders were in second place with a rate of 29.29%, and a general psychiatric examination diagnosis was in third place with a rate of 11.91%. To know the demographic characteristics and clinical diagnoses of people who apply to psychiatric emergency departments in search of help is very important for mental health service planning and development. Larger studies with larger sample groups are needed to generalize and interpret the findings obtained in the present study.
{"title":"Applications to Elazig Mental Hospital Emergency Department in 2021 years","authors":"Nulufer Kilic","doi":"10.5455/medscience.2023.08.128","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.128","url":null,"abstract":"In the present study, the purpose was to analyze the applications made to the emergency department of a mental disease hospital in eastern Turkey. The applications to the mental health and diseases hospital emergency department between 01.01.2021 and 01.01.2022 were examined in the study. The demographic data and psychiatric diagnoses of the patients were recorded. The data of 3712 people who applied to the emergency department of the hospital were analyzed. A total of 37.98% of these patients were hospitalized. Men constituted the majority both in all applications and in patients who were hospitalized for observation and treatment. The most frequent application to the emergency department of the hospital was the patients brought by law enforcement officers with a rate of 26.64%. In patients who were hospitalized, schizophrenia and other psychotic disorders were in first place with a rate of 30.35%, bipolar disorder and mood disorders were in second place with a rate of 29.29%, and a general psychiatric examination diagnosis was in third place with a rate of 11.91%. To know the demographic characteristics and clinical diagnoses of people who apply to psychiatric emergency departments in search of help is very important for mental health service planning and development. Larger studies with larger sample groups are needed to generalize and interpret the findings obtained in the present study.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135651859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.156
Altay Babacan
Iron deficiency anemia (IDA) in children causes both mental and psychomotor impairment. This study was planned to investigate the frequency of iron deficiency anemia in children with poor appetite. Complete blood count and ferritin values of children admitted to the pediatric outpatient clinic due to poor appetite were analyzed retrospectively. Cases with a hemoglobin (Hgb) value below -2 SD and a ferritin level below 12 ng/ml according to the age group were considered as IDA. Four hundred and twenty-eight children aged between 6 months and 18 years were evaluated. 210 (49.06%) and 218 (50.94%) of children were male and female, respectively. Children were examined in four groups according to their age: 1) 6 months-2 years (n=193), 2) 3-6 years (n=142), 3) 7-11 years (n=67) and 4) 12-17 years (n=26). Children were divided into three groups according to their ferritin values: Group 1: ≥12 ng/ml (n=299), Group 2: between 6-12 ng/ml (n=95) and Group 3: ≤6 ng/ml (n=34). The rate of IDA was found to be 28.2% in children with a ferritin value of ≤12 ng/ml. The relationship between age and gender to the frequency of anemia was not statistically significant (p≥0.05). IDA is a common hematological disorder that can be seen at any age, especially in children aged 6-36 months. In children with poor appetite, the presence of iron deficiency should be investigated.
{"title":"Frequency of iron deficiency anemia among children with poor appetite complaint","authors":"Altay Babacan","doi":"10.5455/medscience.2023.08.156","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.156","url":null,"abstract":"Iron deficiency anemia (IDA) in children causes both mental and psychomotor impairment. This study was planned to investigate the frequency of iron deficiency anemia in children with poor appetite. Complete blood count and ferritin values of children admitted to the pediatric outpatient clinic due to poor appetite were analyzed retrospectively. Cases with a hemoglobin (Hgb) value below -2 SD and a ferritin level below 12 ng/ml according to the age group were considered as IDA. Four hundred and twenty-eight children aged between 6 months and 18 years were evaluated. 210 (49.06%) and 218 (50.94%) of children were male and female, respectively. Children were examined in four groups according to their age: 1) 6 months-2 years (n=193), 2) 3-6 years (n=142), 3) 7-11 years (n=67) and 4) 12-17 years (n=26). Children were divided into three groups according to their ferritin values: Group 1: ≥12 ng/ml (n=299), Group 2: between 6-12 ng/ml (n=95) and Group 3: ≤6 ng/ml (n=34). The rate of IDA was found to be 28.2% in children with a ferritin value of ≤12 ng/ml. The relationship between age and gender to the frequency of anemia was not statistically significant (p≥0.05). IDA is a common hematological disorder that can be seen at any age, especially in children aged 6-36 months. In children with poor appetite, the presence of iron deficiency should be investigated.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135651868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.169
Aydin Ocal, Sinem Tekin, Filiz Guleroglu, Omer Eyisoy, Pelin Kulan, Emine Guler, Ali Cetin
The aim of this study was to evaluate fetal lung maturation in term pregnant women with obesity and excessive gestational weight gain using the lamellar body count (LBC) test in amniotic fluid samples obtained during cesarean section. This retrospective study included women experiencing term pregnancies and undergoing cesarean delivery, categorized as normal weight (n=37), overweight (n=59), or obese (n=48) due to body mass index values of 18.5 to 24.9; 25 to 29.9; and ≥30, respectively, as well as presence of excessive weight gain during pregnancy. During cesarean delivery, amniotic fluid samples were obtained without contamination of blood or meconium. Lamellar bodies in these samples were quantified using a standard hematologic counter. No significant difference was found among the LBC of the normal weight, overweight, and obese groups [42 (32-60), 40 (26-63), and 43 (24-52) x103/µL; p=0.307], although there was a subtle decrease in the LBC of the obese group with excessive weight gain. Although it is noteworthy that the LBC in the amniotic fluid of mothers with obesity and excessive weight gain during pregnancy showed a partial decrease, this decrease did not reach statistical significance, likely due to the relatively low number of cases in the study groups. Additional research is warranted to elucidate the relationship between LBC alterations and the severity of obesity and weight gain during pregnancy.
{"title":"Fetal lung maturity assessment with lamellar body count in women with obesity and excessive gestational weight gain","authors":"Aydin Ocal, Sinem Tekin, Filiz Guleroglu, Omer Eyisoy, Pelin Kulan, Emine Guler, Ali Cetin","doi":"10.5455/medscience.2023.08.169","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.169","url":null,"abstract":"The aim of this study was to evaluate fetal lung maturation in term pregnant women with obesity and excessive gestational weight gain using the lamellar body count (LBC) test in amniotic fluid samples obtained during cesarean section. This retrospective study included women experiencing term pregnancies and undergoing cesarean delivery, categorized as normal weight (n=37), overweight (n=59), or obese (n=48) due to body mass index values of 18.5 to 24.9; 25 to 29.9; and ≥30, respectively, as well as presence of excessive weight gain during pregnancy. During cesarean delivery, amniotic fluid samples were obtained without contamination of blood or meconium. Lamellar bodies in these samples were quantified using a standard hematologic counter. No significant difference was found among the LBC of the normal weight, overweight, and obese groups [42 (32-60), 40 (26-63), and 43 (24-52) x103/µL; p=0.307], although there was a subtle decrease in the LBC of the obese group with excessive weight gain. Although it is noteworthy that the LBC in the amniotic fluid of mothers with obesity and excessive weight gain during pregnancy showed a partial decrease, this decrease did not reach statistical significance, likely due to the relatively low number of cases in the study groups. Additional research is warranted to elucidate the relationship between LBC alterations and the severity of obesity and weight gain during pregnancy.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135104938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.153
Mustafa Demir, Davut Guven, Ilhami Ersoy
The aim of this research was to analyze the link between endometrial thickness (EMT), as measured during progesterone administration, and the results observed in individuals who underwent frozenthawed embryo transfer. A retrospective analysis was performed on 233 hormone replacement therapy (HRT) methods of endometrial preparation in frozen-thawed embryo transfer (FET) cycles (HRT-FET). HRT-FET cycles that were conducted between January 2021 and December 2022 at the In vitro fertilization (IVF) Clinic of 19 May University Medical Faculty Training and Research Hospital. The patients' age, infertility duration, basal follicle-stimulating hormone (FSH) level, body mass index (BMI), number and day of embryos transferred, and pregnancy rates were evaluated. Endometrial thickness was measured using transvaginal ultrasound (TV USG) on the day of progesterone administration. The endometrial thickness of patients who achieved clinical pregnancy and those who did not were analyzed. No significant differences in demographic factors were found between the groups in terms of age, infertility duration, basal FSH level, and BMI (p=0.209, p=0.959, p=0.866 and p=0.685, respectively) . The success rates of clinical pregnancy did not strongly correlate with endometrial thickness. The study found that EMT is not a valid indicator for clinical pregnancy in frozen-thawed embryo transfer cycles.
{"title":"Evaluation of the IVF success in frozen-thaw in vitro fertilization cycles in terms of endometrial thickness","authors":"Mustafa Demir, Davut Guven, Ilhami Ersoy","doi":"10.5455/medscience.2023.08.153","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.153","url":null,"abstract":"The aim of this research was to analyze the link between endometrial thickness (EMT), as measured during progesterone administration, and the results observed in individuals who underwent frozenthawed embryo transfer. A retrospective analysis was performed on 233 hormone replacement therapy (HRT) methods of endometrial preparation in frozen-thawed embryo transfer (FET) cycles (HRT-FET). HRT-FET cycles that were conducted between January 2021 and December 2022 at the In vitro fertilization (IVF) Clinic of 19 May University Medical Faculty Training and Research Hospital. The patients' age, infertility duration, basal follicle-stimulating hormone (FSH) level, body mass index (BMI), number and day of embryos transferred, and pregnancy rates were evaluated. Endometrial thickness was measured using transvaginal ultrasound (TV USG) on the day of progesterone administration. The endometrial thickness of patients who achieved clinical pregnancy and those who did not were analyzed. No significant differences in demographic factors were found between the groups in terms of age, infertility duration, basal FSH level, and BMI (p=0.209, p=0.959, p=0.866 and p=0.685, respectively) . The success rates of clinical pregnancy did not strongly correlate with endometrial thickness. The study found that EMT is not a valid indicator for clinical pregnancy in frozen-thawed embryo transfer cycles.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135157659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.170
Sevda Akdeniz, Hatice Kusderci, Senay Adiguzel
This study compares the code blue calls (CBCs) used in our hospital before and during the COVID-19 pandemic. CBCs made between 31.03.2018 and 31.03.2022 in the Samsun Maternity and Child Health Training and Research Hospital were examined retrospectively. The study period was subdivided into two sections, one from March 31, 2018, to March 30, 2020 (Group 1, the pre-pandemic period) and the other from March 31, 2020, to March 31, 2022 (Group 2, the pandemic period). Patients' demographic data, the reason for the CBC and where it was issued, the time elapsed before the team arrived on the scene, and the outcomes were then compared between the groups. Seventy-nine CBCs, 34 (43.1%) of which were ‘false,’ were included in the study. Forty-six calls were made in the pre-pandemic period, 26 (56.5%) of which were true calls, while 33 calls were made during the pandemic, of which 19 (57.6%) were true calls. Twenty-seven (60%) of the 45 true CBCs were for boys and 18 (40%) for girls. The children’s mean age was 73.06±66.85 months, and 57.7% of the CBCs were issued during the pre-pandemic period. No significant difference was observed between groups 1 and 2 in terms of code blue team arrival times (114.03±59.14 vs. 138.1±95.96 sec, respectively (P=.305). The total mortality rate at the end of 30 days was 13.3% (P=.679). No difference was observed in CBC results between the pre-pandemic and pandemic periods in this study. We think that some blue code parameters, such as false calls and blue code team arrival times, can be improved through effective training against potential future pandemics.
{"title":"A comparison of code blue calls in a tertiary pediatric hospital in the pre-pandemic and pandemic periods","authors":"Sevda Akdeniz, Hatice Kusderci, Senay Adiguzel","doi":"10.5455/medscience.2023.08.170","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.170","url":null,"abstract":"This study compares the code blue calls (CBCs) used in our hospital before and during the COVID-19 pandemic. CBCs made between 31.03.2018 and 31.03.2022 in the Samsun Maternity and Child Health Training and Research Hospital were examined retrospectively. The study period was subdivided into two sections, one from March 31, 2018, to March 30, 2020 (Group 1, the pre-pandemic period) and the other from March 31, 2020, to March 31, 2022 (Group 2, the pandemic period). Patients' demographic data, the reason for the CBC and where it was issued, the time elapsed before the team arrived on the scene, and the outcomes were then compared between the groups. Seventy-nine CBCs, 34 (43.1%) of which were ‘false,’ were included in the study. Forty-six calls were made in the pre-pandemic period, 26 (56.5%) of which were true calls, while 33 calls were made during the pandemic, of which 19 (57.6%) were true calls. Twenty-seven (60%) of the 45 true CBCs were for boys and 18 (40%) for girls. The children’s mean age was 73.06±66.85 months, and 57.7% of the CBCs were issued during the pre-pandemic period. No significant difference was observed between groups 1 and 2 in terms of code blue team arrival times (114.03±59.14 vs. 138.1±95.96 sec, respectively (P=.305). The total mortality rate at the end of 30 days was 13.3% (P=.679). No difference was observed in CBC results between the pre-pandemic and pandemic periods in this study. We think that some blue code parameters, such as false calls and blue code team arrival times, can be improved through effective training against potential future pandemics.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135056614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.131
Hamit Kizil, Sinan Bayram, Serdar Ozturk, Umit Karakas
Melanins, which are divided into five different subgroups as eumelanin, pheomelanin, allomelanin, neuromelanin and pyomelanin, are a heterogeneous and amorphous biopolymer family. Although melanin is produced in many different ways today, it is more practical, and more economical to produce melanin using bacterial strains. The eumelanin pigment, which is the subject of this study, was obtained using Streptomyces parvus BSB49 strain, and its antiproliferative effect at various concentrations against small cell (DMS-114) and non-small cell (H-460) lung cancer was determined. According to our results, the synthesized eumelanin molecule was statistically cytotoxic on non-small cell lung cancer cell line (H-460) at concentrations of 3.125 and 1.56 μg/mL after 24 hours of treatment (IC50=8 μg/mL) and only at a concentration of 3.125 μg/mL after 48 hours of treatment (IC50=8.4 μg/mL). In the small cell lung cancer cell line (DMS-114), no statistically cytotoxic concentration was detected (p<0.05).
{"title":"Could eumelanin molecule from Streptomyces parvus BSB49 strain be a potential anticancer agent for lung cancer?","authors":"Hamit Kizil, Sinan Bayram, Serdar Ozturk, Umit Karakas","doi":"10.5455/medscience.2023.08.131","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.131","url":null,"abstract":"Melanins, which are divided into five different subgroups as eumelanin, pheomelanin, allomelanin, neuromelanin and pyomelanin, are a heterogeneous and amorphous biopolymer family. Although melanin is produced in many different ways today, it is more practical, and more economical to produce melanin using bacterial strains. The eumelanin pigment, which is the subject of this study, was obtained using Streptomyces parvus BSB49 strain, and its antiproliferative effect at various concentrations against small cell (DMS-114) and non-small cell (H-460) lung cancer was determined. According to our results, the synthesized eumelanin molecule was statistically cytotoxic on non-small cell lung cancer cell line (H-460) at concentrations of 3.125 and 1.56 μg/mL after 24 hours of treatment (IC50=8 μg/mL) and only at a concentration of 3.125 μg/mL after 48 hours of treatment (IC50=8.4 μg/mL). In the small cell lung cancer cell line (DMS-114), no statistically cytotoxic concentration was detected (p<0.05).","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.5455/medscience.2023.08.178
Mehmet Okyay
Our study aims to investigate the seasonal effects on the breath and quality of life (QoL) of patients who underwent septorhinoplasty (SRP). A total of 52 patients who underwent SRP between 2018-2023 were included in the study. Two groups those who operated in the winter (winter group, n=26) and those who performed in the summer (summer group, n=26) were evaluated with the NOSE (Nasal Obstruction Symptom Evaluation) scale to reveal the QoL after surgery. Compared with the summer group, NOSE scores in the winter group showed a statistically significant difference (p<0.05). Septorhinoplasty is a surgical procedure expected to increase the QoL of patients regardless of the season and climate. The low mean NOSE score observed in the winter showed that the postoperative patient comfort was significantly higher compared who underwent surgery in the summer. Therefore, encouraging patients to undergo surgery intensively during the winter months in SRP will be positive for postoperative QoL. Future studies may reveal more illuminating results for increasing patient comfort by considering different surgical techniques, climates, and months.
{"title":"Effects of seasonal conditions on septorhinoplasty patients","authors":"Mehmet Okyay","doi":"10.5455/medscience.2023.08.178","DOIUrl":"https://doi.org/10.5455/medscience.2023.08.178","url":null,"abstract":"Our study aims to investigate the seasonal effects on the breath and quality of life (QoL) of patients who underwent septorhinoplasty (SRP). A total of 52 patients who underwent SRP between 2018-2023 were included in the study. Two groups those who operated in the winter (winter group, n=26) and those who performed in the summer (summer group, n=26) were evaluated with the NOSE (Nasal Obstruction Symptom Evaluation) scale to reveal the QoL after surgery. Compared with the summer group, NOSE scores in the winter group showed a statistically significant difference (p<0.05). Septorhinoplasty is a surgical procedure expected to increase the QoL of patients regardless of the season and climate. The low mean NOSE score observed in the winter showed that the postoperative patient comfort was significantly higher compared who underwent surgery in the summer. Therefore, encouraging patients to undergo surgery intensively during the winter months in SRP will be positive for postoperative QoL. Future studies may reveal more illuminating results for increasing patient comfort by considering different surgical techniques, climates, and months.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarcomas are a heterogeneous group of malignant tumors of mesenchymal origin. 18 Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET)/Computed Tomography (CT) is a combined imaging modality that could provide an anatomic and functional assessment of many solid tumors. In this study, the association between primary tumor characteristics (grade, histologic type, stage, localization) and the FDG-PET/ CT data of the primary tumor at the diagnosis were evaluated. The study aimed to determine the diagnostic role of numerical metabolic values determined in PET/CT in predicting grade, prognosis, and other patient characteristics of sarcoma patients. Patients with soft tissue and bone sarcoma who applied to the oncology department of Gazi University Faculty of Medicine between 2000 and 2014 were evaluated retrospectively. All patients underwent PET imaging with FDG before initiation of neoadjuvant chemotherapy or resection. Sarcoma patients (27 soft tissue, 18 bone sarcoma) were evaluated retrospectively in this study. Tumor size was found to correlate with SUVmax. Histologic grade was found to be associated with tumor 18F-FDG, but this was not statistically significant because of the small patient number. The optimal cut-off SUVmax value in showing the difference between low and high grades was 5.5. Overall survival was shown to be shorter in patients with SUVmax ≥5.5. In this study, we aimed to show the relationship between histologic grade and tumor metabolic activity. PET-CT could give an idea about tumor histologic grade and predict survival. It has an important role in diagnosis and also in determining the prognosis.
{"title":"PET/CT, an important imaging modality in the management of sarcoma patients","authors":"Esra Erdogan, Aytug Uner, Ozge Gumusay, Umit Akdemir","doi":"10.5455/medscience.2023.09.187","DOIUrl":"https://doi.org/10.5455/medscience.2023.09.187","url":null,"abstract":"Sarcomas are a heterogeneous group of malignant tumors of mesenchymal origin. 18 Fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET)/Computed Tomography (CT) is a combined imaging modality that could provide an anatomic and functional assessment of many solid tumors. In this study, the association between primary tumor characteristics (grade, histologic type, stage, localization) and the FDG-PET/ CT data of the primary tumor at the diagnosis were evaluated. The study aimed to determine the diagnostic role of numerical metabolic values determined in PET/CT in predicting grade, prognosis, and other patient characteristics of sarcoma patients. Patients with soft tissue and bone sarcoma who applied to the oncology department of Gazi University Faculty of Medicine between 2000 and 2014 were evaluated retrospectively. All patients underwent PET imaging with FDG before initiation of neoadjuvant chemotherapy or resection. Sarcoma patients (27 soft tissue, 18 bone sarcoma) were evaluated retrospectively in this study. Tumor size was found to correlate with SUVmax. Histologic grade was found to be associated with tumor 18F-FDG, but this was not statistically significant because of the small patient number. The optimal cut-off SUVmax value in showing the difference between low and high grades was 5.5. Overall survival was shown to be shorter in patients with SUVmax ≥5.5. In this study, we aimed to show the relationship between histologic grade and tumor metabolic activity. PET-CT could give an idea about tumor histologic grade and predict survival. It has an important role in diagnosis and also in determining the prognosis.","PeriodicalId":18541,"journal":{"name":"Medicine Science | International Medical Journal","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135058844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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