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Features of the formation and course of late acquired myopia 晚期获得性近视的形成及病程特点
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-306-311
N. A. Nefedov, A. S. Aleksandrov, K.S. Korneva, Z. Kushim, V.V. Sukhanov
Introduction. In the modern world, the load on vision has significantly increased, the widespread introduction of computer technology has led to additional visual load, both during working hours and at home. Prolonged and strenuous visual work can lead to the emergence of professional ophthalmopathy, one of the leading manifestations of which is myopia, which develops in persons with visually strenuous work. Goal. To investigate the features of the formation and course of myopia in adults. Material and methods. A retrospective study was conducted based on ophthalmological examination data during the medical examination of the attached contingent in the period 2020-2023 (n=1506). Among them there were 1202 men (79.8%) and 304 women (20.2%). During the examination 416 people (27.6%) were found to be healthy. Refraction and accommodation disorders were detected in 1076 people (71.6%), other visual diseases – in 14 people (0.8%). Among the violations of refraction and accommodation, the leading (50.3%) were: myopia (29.9%), myopic astigmatism (17.6%) and mixed astigmatism (2.8%). The age at which myopia occurred, the degree of clinical refraction, the rate of progression, and the magnitude of anisometropia were evaluated. Results. In 153 people (20.2%), myopia manifested at the age of 34.3+7.2 years (18;52). At the time of examination, the duration of myopia was 7.3+5.9 years (0; 30). In the period 2020-2021, the proportion of late myopia left 14.0%, and in 2022-2023 – 28.8% (p<0.001). Stationary course of late myopia was noted in 5.9% of cases, progression – in 90.2% (slow (0.5 dptr per year or less) – 77.8%; fast (more than 0.5 dptr per year – 7.2%). The proportion of mild myopia was 92.9%, medium – 6.5%, high – 0.7%. Isometropia was observed in 44.4% of cases, anisometropia up to 0.5 dpt – in 34.7% of cases, anisometropia with a degree of 0.75 dpt and more – in 20.9% of cases Conclusion. During the medical examination, 71.6% of the examined contingent revealed violations of refraction and accommodation, including 50.3% of individuals diagnosed with myopic refraction. Nearsightedness manifested at the age of 18 and older was observed in 20.2% of people with myopia. The data obtained confirm the need for therapeutic and preventive measures to prevent the formation and progression of myopia in adults. Keywords: myopia, adults, professional ophthalmopathy, refraction, accommodation
介绍。在现代社会,视觉负荷显著增加,计算机技术的广泛采用导致了额外的视觉负荷,无论是在工作时间还是在家里。长时间和艰苦的视觉工作可导致专业眼病的出现,其中一个主要表现是近视,这发生在视觉艰苦工作的人身上。的目标。目的:探讨成人近视的形成和发展特点。材料和方法。根据2020-2023年附队体检期间眼科检查资料(n=1506)进行回顾性研究。其中男性1202人(79.8%),女性304人(20.2%)。在检查期间,416人(27.6%)被发现是健康的。屈光和适应障碍1076人(71.6%),其他视力疾病14人(0.8%)。屈光不正和屈光不正发生率最高的是近视(29.9%)、近视散光(17.6%)和混合性散光(2.8%),占50.3%。评估发生近视的年龄、临床屈光程度、进展速度和屈光参差程度。结果。153人(20.2%)在34.3+7.2岁时出现近视(18;52)。检查时,近视持续时间为7.3+5.9年(0;30). 2020-2021年晚期近视比例为14.0%,2022-2023年为28.8% (p<0.001)。5.9%的病例有迟发性近视病程,90.2%的病例有进展(缓慢(每年0.5 dptr或更少)77.8%;快速(每年超过0.5 DPTR - 7.2%)。轻度近视占92.9%,中度- 6.5%,高度- 0.7%。屈光参差达0.5 dpt者占34.7%,屈光参差达0.75 dpt者占20.9%。在体检期间,71.6%被检查的特遣队发现违反屈光和调节规定,其中50.3%的人被诊断为近视屈光。在18岁及以上的近视患者中,有20.2%的人表现为近视。所获得的数据证实需要采取治疗和预防措施来防止成人近视的形成和发展。关键词:近视,成人,专业眼病,屈光,调节
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引用次数: 0
Efficacy of intrastromal corneal ring segments in the treatment of keratoconus with irregular asymmetric paracentral astigmatism 角膜间环段治疗圆锥角膜不规则不对称中央旁散光的疗效观察
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-199-204
S. Volik, S.V. Kren, A. N. Khalilov
Purpose. To evaluate the efficacy and safety of implantation of intrastromal corneal ring segments ICRS (IRS NEP MNTC) in patients with keratoconus with irregular asymmetric paracentral astigmatism. Material and methods. 14 patients (16 eyes) with keratoconus stage II–III with irregular asymmetric paracentral astigmatism were evaluated before and after ICRS (IRS NEP MNTC). The tunnels for ICRS implantation were created with a femtosecond laser. ICRSThe effectiveness was assessed on the basis of an increase in uncorrected and corrected visual acuity in the postoperative period, as well as the absence of keratectasia progression in the period from 10 to 18 months after ICRS implantation. Results. All ICRS were implanted in 16 eyes without intra and postoperative complications. Uncorrected distance visual acuity (UDVA) increased from 0.16 ± 0.12 preoperatively to 0.54 ± 0.24 at the 6th month of postoperative follow-up. Corrected distance visual acuity (CDVA) increased from 0.38 ± 0.2 to 0.72 ± 0.34 at the 6th month of postoperative follow-up. The refractive index decreased from preoperative mean –3.56 ± 2.4 D to –2.02 ± 1.4D at the 6th month of postoperative follow-up. The average maximum value of the K index decreased from the preoperative 54.60 ± 3.25 D (in the range from 46.25 to 64.50 D) to the 6-month postoperative value of 45.54 ± 2.72D. Conclusions. The implantation of OCRS in eyes with keratoconus stage II-III with irregular asymmetric paracentral astigmatism is an effective and safe method of increasing visual acuity and reducing refractive errors. Keywords: keratoconus, intrastromal corneal ring segments
目的。评价角膜环段ICRS (IRS NEP MNTC)植入术治疗不规则非对称圆锥角膜中央旁散光的疗效和安全性。材料和方法。对14例(16眼)伴有不规则非对称中央旁散光的II-III期圆锥角膜患者进行ICRS (IRS NEP MNTC)前后评价。利用飞秒激光建立了ICRS植入通道。ICRS的有效性评估基于术后未矫正和矫正视力的增加,以及ICRS植入后10至18个月期间无角膜扩张进展。结果。所有ICRS植入16只眼,无术中及术后并发症。未矫正距离视力(UDVA)由术前的0.16±0.12提高到术后6个月的0.54±0.24。术后6个月矫正距离视力(CDVA)由0.38±0.2提高至0.72±0.34。术后6个月屈光指数由术前平均-3.56±2.4 D降至-2.02±1.4D。K指数的平均最大值从术前的54.60±3.25 D (46.25 ~ 64.50 D)下降到术后6个月的45.54±2.72D。结论。晶状体圆锥角膜II-III期不规则非对称旁中心散光患者植入术是一种安全有效的提高视力和减少屈光不正的方法。关键词:圆锥角膜;角膜间环段
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引用次数: 0
Analysis of the volume and structure of emergency surgical care in severe mechanical trauma of the eyeball 重型机械性眼球外伤急诊外科护理的体积与结构分析
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-280-285
A.A. Buldygin, A. V. Tereshchenko, I. G. Trifanenkova, N. Yudina, N. Shilov
Purpose. To analyze the volume and structure of emergency surgical care for patients admitted to the admission department of the S. Fyodorov Eye Microsurgery Federal State Institution with severe mechanical trauma to the eyeball. Material and methods. In total, for the period from 2020 to 2022, 92 patients with an eye injury were admitted to the admission department of the S. Fyodorov Eye Microsurgery Federal State Institution. Results. Gender and age analysis showed that the average age of the group of patients from 18 to 78 years was 37.4 years. The patients were men in the vast majority of cases (86%). The domestic eye injury occupies the leading position – 81%. The source of injuries in a greater percentage of cases (30%) are electrical construction tools, in second place (19%) is mechanical impact with a blunt object, in third place (16%) are manual construction tools. Among the types of injuries, the most common injury is the cornea (37%), as well as a large percentage of patients with contusion and ruptures due to contusion (29.3%). The total number of patients who applied to the emergency department with uveitis and endophthalmitis was 18 or 19.57% of the total. Among them, there were 6 patients after primary surgical treatment of the eye at the place of residence – (33.3%). Primary surgical treatment of the eye was carried out in the period from 1 to 4 days. The period of application to the S. Fyodorov Eye Microsurgery Federal State Institution ranged from 5 to 93 days. In patients with self-referral (12 patients or 66.7%), the referral period was from 3 to 7 days. Conclusion. Eye injury is a socially significant problem, as it affects people of working age. The performed analysis allows to speak about a wide variety of injury mechanisms and traumatic agents. In almost 20% of cases, severe mechanical trauma of the eye was complicated by uveitis or endophthalmitis. This, in most cases, was due to the late treatment of patients for specialized medical care. Keywords: mechanical injury of the eye, mechanism of eye injury, structure of emergency surgical care
目的。目的分析S. Fyodorov眼科显微外科联邦州立机构住院部收治的眼球严重机械损伤患者的急诊外科护理的数量和结构。材料和方法。在2020年至2022年期间,总共有92名眼部损伤患者入住S. Fyodorov眼科显微外科联邦国家机构的住院部。结果。性别和年龄分析显示,18 ~ 78岁的患者平均年龄为37.4岁。绝大多数病例(86%)为男性。国内眼外伤占领先地位——81%。在大多数情况下,造成伤害的原因是电气施工工具(30%),其次是钝器的机械撞击(19%),第三位是手动施工工具(16%)。在损伤类型中,最常见的损伤是角膜(37%),挫伤和挫伤导致的破裂也占很大比例(29.3%)。以葡萄膜炎和眼内炎向急诊科申请的患者总数为18例,占总数的19.57%。其中,原发居住地眼部手术治疗后6例(33.3%)。术后1 ~ 4天进行眼部手术治疗。向S. Fyodorov眼科显微外科联邦州立机构申请的期限为5至93天。自我转诊患者(12例,占66.7%),转诊时间为3 ~ 7天。结论。眼伤是一个重大的社会问题,因为它影响到工作年龄的人。所进行的分析允许谈论各种各样的损伤机制和创伤因素。在近20%的病例中,严重的眼机械损伤并发葡萄膜炎或眼内炎。在大多数情况下,这是由于病人接受专门医疗护理治疗较晚所致。关键词:眼机械损伤,眼损伤机制,急诊外科护理结构
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引用次数: 0
Algorithm for the diagnosis of keratoectasias developed after refractive surgery 屈光术后角膜扩张的诊断算法
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-293-297
H. M. Kamilov, M. S. Kasymova, G. Khamraeva, D.F. Ismailova
Purpose. On the basis of modern methods of clinical examination to develop an optimal diagnostic algorithm for early detection of keratoectasia. Material and methods. We observed 73 patients (110 eyes) with keratoectasia developed after refractive surgery. The age of the patients ranged from 22 to 64 years, of which 36 were women and 37 were men. All patients underwent general ophthalmological and special research methods. Results. Keratotopography of patients with keratectasia revealed thinning in the central part of the cornea, an increase in the posterior surface of the cornea was found in the posterior elevation map, and the curvature of the cornea averaged 42.8 dpt. In keratoectasia, the average loss of endothelial cells was 65 % of the norm, while the average density of endothelial cells was 1189 ± 91.9 cells/mm², with a norm of 2863.7 ± 54.29 cells/ mm². This is 58.5 % lower than normal. Conclusions. Early application of endothelial microscopy, keratotopography, optical coherence tomography allows to assess the condition of the cornea and take the necessary measures in the early stages of keratectasia developed after refractive surgery. Keywords: cornea, iatrogenic keratoectasia, keratoconus, endothelial microscopy, keratotopography, optical coherence tomography
目的。在现代临床检查方法的基础上,发展出早期发现角膜扩张症的最佳诊断算法。材料和方法。我们观察了73例(110只眼)屈光手术后发生的角膜扩张。患者年龄22 ~ 64岁,其中女性36例,男性37例。所有患者均行普通眼科学和特殊研究方法。结果。角膜扩张患者的角膜地形图显示角膜中部变薄,角膜后立面图显示角膜后表面增加,角膜曲率平均42.8 dpt。在角膜扩张症中,内皮细胞的平均损失为正常值的65%,内皮细胞的平均密度为1189±91.9个细胞/mm²,正常值为2863.7±54.29个细胞/mm²。这比正常情况低58.5%。结论。早期应用内皮显微镜、角膜地形学、光学相干断层扫描可以评估角膜状况,并在屈光手术后发生的角膜扩张的早期阶段采取必要的措施。关键词:角膜,医源性角膜扩张,圆锥角膜,内皮显微镜,角膜地形图,光学相干断层扫描
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引用次数: 0
The influence of antiglaucoma drugs and its components on cultured human corneal endothelial cells 抗青光眼药物及其成分对培养人角膜内皮细胞的影响
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-85-91
N. Fisenko, A. Subbot, G. A. Osipyan
Purpose. Evaluation of cytotoxicity of antiglaucoma drugs and preservative – benzalkonium chloride (BAK) in human corneal endothelial cells (CECs) in vitro. Material and methods. High-CEC-density colonies were used as a monolayer (intact endothelium in vivo) and single CECs were regarded as low-HCEC-density layer in bullous keratopathy. Dorzolamide, brimonidine, timolol (preserved and BAK-free) were diluted with medium up to 1/10000, 1/1000, 1/100. BAK was diluted according to its concentration in these solutions. Following exposure to test solutions for 24 hours, morphological features of both CEC-models were identified with phase-contrast microscope, CECs survival was measured using MTS assay. Results. Dorzolamide and Timolol, preservative-free, 1/1000 and 1/100 dilutions, induced structural changes of single CECs. Timolol, preservative-free, 1/1000 and 1/100 dilutions, caused changes of CEC-monolayer. Dorzolamide, brimonidine and timolol (preservative-free, 1/100 dilutions) have not caused the decline of CEC viability in both models. Dorzolamide, preserved, 1/100 dilution, was toxic to CEC-monolayer. Brimonidine and timolol (preserved, 1/100 dilutions) induced CECs'death in monolayer. Low single CECs viability (29%) was detected after exposure to Dorzolamide, preserved, 1/100 dilution. High cytotoxicity of brimonidine and timolol (both preserved, 1/100 dilutions) to CEC-monolayer was confirmed by MTS-test – 25% and 3%, respectively and to single CECs – 23,4% and 4,2%, respectively. BAK showed similar level of CECs'toxicity as preserved drugs. So, the cytotoxicity of these drugs was induced by BAK as a component. Conclusions. High concentrations of preserved antiglaucoma ophthalmic solutions may disturb CECs. Administration of such drugs is not reasonable in eyes with low corneal endothelial cell density. Keywords: dorzolamide, brimonidine, timolol, benzalkonium chloride, corneal endothelium, cytotoxicity
目的。抗青光眼药物和防腐剂苯扎氯铵(BAK)体外对人角膜内皮细胞的细胞毒性评价。材料和方法。在大疱性角膜病变中,高CECs密度的菌落被视为单层(体内完整的内皮细胞),而单个CECs被视为低CECs密度的层。Dorzolamide, brimonidine, timolol(保存和无bak)用培养基稀释至1/10000,1/1000,1/100。根据BAK在这些溶液中的浓度进行稀释。实验溶液暴露24小时后,用相差显微镜观察两种CECs模型的形态学特征,用MTS法测定CECs存活率。结果。Dorzolamide和Timolol,不含防腐剂,1/1000和1/100稀释,诱导单个cec的结构变化。替莫洛尔,不含防腐剂,1/1000和1/100稀释,引起cec单层的变化。Dorzolamide, brimonidine和timolol(不含防腐剂,1/100稀释)在两种模型中均未引起CEC活力下降。经1/100稀释保存的多唑胺对cec单层细胞有毒性。溴莫尼定和噻莫洛尔(保存,1/100稀释)单层诱导CECs死亡。暴露于Dorzolamide,保存,1/100稀释后,检测到低单个CECs活力(29%)。mts试验证实溴胺定和噻莫洛尔(均为保存,1/100稀释度)对单层CECs的细胞毒性分别为25%和3%,对单层CECs的细胞毒性分别为23.4%和4.2%。BAK显示出与保存药物相似的CECs毒性水平。因此,这些药物的细胞毒性是由BAK作为一个成分诱导的。结论。高浓度保存的抗青光眼眼液可能会干扰cec。在角膜内皮细胞密度低的眼睛中使用这类药物是不合理的。关键词:多唑胺,溴莫尼定,替莫洛尔,苯扎氯铵,角膜内皮,细胞毒性
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引用次数: 0
The results of amnioplasty using two-component autofibrin glue in surgical treatment of pterygium 双组份自体纤维蛋白胶羊膜成形术治疗翼状胬肉的效果
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-109-114
Y. Kozlova, S. V. Churashov, A. Kulikov, A. Malafeeva
The only effective way of pterygium treatment is its removal with defect plasty by different tissues, including amniotic membrane. The choice of fixation method that will ensure maximum efficiency and minimize recurence risk remains actual. Using sutures increases operation time and leads to discomfort of patient in postoperative period. A comparative analysis of effectiveness of surgical treatment using designed by us two-component autofibrin glue and sutures for fixing the amniotic membrane was done. The study included 32 patients, they were divided into 2 groups depending on the method of fixing the amniotic membrane: the 1st group was the main group (22 patients), where the amniotic membrane was fixed with a two-component autofibrin glue, the 2nd group (10 patients) was the control group, where the sutures were used. Before and after surgery all patients underwent biomicroscopy and optical coherence tomography of the anterior segment, the groups were compared by the time spent on the operation, duration of epithelization and rehabilitation, as well as presence of discomfort in postoperative period. The presence of pterygium recurrence in the study groups was assessed during 12-month observation. During our study we found statistically significant differences between groups, which show the advantages of fixing amniotic membrane with two-component autofibrin glue. During 12-month observation one case of recurrence was fixed after using fixation by sutures. This makes possible to choose two-component autofibrin glue as a fixation method of amniotic membrane in pterygium surgery. Keywords: pterygium, autofibrin glue, surgical treatment, amniotic membrane, fixation
治疗翼状胬肉的唯一有效方法是用不同组织(包括羊膜)进行缺损切除。固定方法的选择将确保最大的效率和最小的复发风险仍然是实际的。使用缝线增加了手术时间,导致患者术后不适。比较分析了我们设计的双组分自体纤维蛋白胶与缝线固定羊膜的手术治疗效果。本研究纳入32例患者,根据羊膜固定方法分为两组:第一组为主组(22例),采用双组分自体纤维蛋白胶固定羊膜;第二组(10例)为对照组,采用缝线固定羊膜。所有患者术前、术后均行生物显微镜及前段光学相干断层扫描,比较两组手术时间、上皮化及康复时间、术后不适情况。在12个月的观察中评估研究组中翼状胬肉复发的情况。在我们的研究中,我们发现组间差异有统计学意义,这表明双组分自体纤维蛋白胶固定羊膜的优势。在12个月的观察中,1例复发采用缝合固定。这使得在翼状胬肉手术中选择双组分自体纤维蛋白胶作为羊膜固定方法成为可能。关键词:翼状胬肉;自体纤维蛋白胶;手术治疗
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引用次数: 0
Analysis of the causes of eye removal surgeries at the present stage 现阶段眼球摘除手术的原因分析
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-149-151
I. A. Yakovlev, A. M. Revta, D. Seliverstova, A. M. Bezhanidze
Retrospective analysis of the case histories of 243 patients (111 men and 132 women) aged 6 months to 96 years who underwent eye removal operations (22 eviscerations and 221 enucleations) was conducted. In the structure of clinical indications for enucleation and evisceration of the eye dominated severe pyo-inflammatory processes (infectious ulcer with corneal perforation, endophthalmitis, panophthalmitis, chronic sluggish uveitis with the threat of sympathetic ophthalmia) – 46.5 %. The percentage of malignant neoplasm (melanoma and retinoblastoma) is 27.9 %. Painful absolute glaucoma was the cause of enucleation in 18.9 %, severe eye injury in 6.5 % of patients. Radical surgeries were more often performed in women of the older age group with inflammatory pathology and oncopathology, men were more often operated on for painful absolute glaucoma and eye injury. Keywords: еnucleation; еvisceration; аnophthalmia
回顾性分析243例(男111例,女132例)6个月~ 96岁行眼球摘除手术(摘除22例,剜出221例)的病例史。在临床指征结构中,眼球摘除术和内脏切除主要是严重的脓性炎症过程(感染性溃疡伴角膜穿孔、眼内炎、全眼炎、慢性迟滞性葡萄膜炎伴交感眼炎威胁)- 46.5%。恶性肿瘤(黑色素瘤和视网膜母细胞瘤)的比例为27.9%。疼痛性绝对青光眼占18.9%,严重眼外伤占6.5%。根治性手术多见于有炎症病理和肿瘤病理的老年女性,男性多见于疼痛性青光眼和眼损伤。关键词:е成核;еvisceration;аnophthalmia
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引用次数: 0
Analysis of the effectiveness of surgical treatment of malignant glaucoma 恶性青光眼手术治疗效果分析
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-376-380
D.B. Danzandorzhieva, A. Trofimov, V.I. Grigorichev, T. Iureva
Purpose. To analyze the types of treatment of malignant glaucoma and their effectiveness using clinical examples. Material and methods. 3 patients with malignant glaucoma were included, with a history of phacoemulsification with implantation of an intraocular lens at different times. All patients underwent a complete ophthalmological examination, including visometry, tonometry, biometry, ultrasound B-scan, biomicroscopy, and surgical treatment of malignant glaucoma, consisting of posterior closed vitrectomy 25 G, iridectomy and capsulotomy. Results. All cases resulted in a favorable outcome after the treatment. Conclusion. The study proved that an effective surgical treatment patients diagnosed with malignant glaucoma, after cataract phacoemulsification with intraocular lens implantation, is to perform a posterior closed vitrectomy 25 G with iridectomy and capsulotomy. Keywords: malignant glaucoma, a posterior closed vitrectomy
目的。结合临床实例分析恶性青光眼的治疗方法及疗效。材料和方法。3例恶性青光眼患者,均有不同时间的超声乳化术合并人工晶状体植入术。所有患者均行完整的眼科检查,包括粘度计、眼压计、生物计、b超、生物显微镜检查,并行恶性青光眼手术治疗,包括后路闭式玻璃体切除术25g、虹膜切除术和囊膜切除术。结果。所有病例经治疗后均获得良好的预后。结论。本研究证实,对确诊为恶性青光眼的白内障超声乳化术合并人工晶状体植入术后行后路闭式玻璃体切除术25g联合虹膜切除术和囊膜切除术是一种有效的手术治疗方法。关键词:恶性青光眼,闭合性玻璃体切除术
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引用次数: 0
Features of diagnosis and treatment of glaucoma in young people 青光眼的诊断与治疗特点
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-273-279
A. A. Bratchuk, S. Anisimova, L. Arutyunyan, S. Anisimov
Purpose. To reveal the features of diagnosis and treatment of glaucoma in a group of young patients. Material and methods. Complex ophthalmological examination of 10 young patients diagnosed with glaucoma. Among them, three are on conservative treatment, the rest underwent non-penetrating deep sclerectomy with Xenoplast drainage implantation. Results. Patients who have undergone surgical treatment, especially in the early stages of glaucoma, are able to stabilize the pathological process, while maintaining visual functions at a high level. In an unoperated patient with myopia and nNDST, on maximum antihypertensive therapy, a negative trend was noted according to OCT. In the only case, a patient with emmetropia has stable indicators for several years on drug treatment (prostaglandin analogues). Conclusion. Timely diagnosis and implementation of nonpenetrating deep sclerectomy in the early stages are the main links in the successful treatment of young glaucoma. Patients with axial myopia and glaucoma should be evaluated cardiologically and orthopedically for signs of connective tissue damage. Undifferentiated connective tissue dysplasia may be the pathophysiological basis of the glaucoma process. Key words: glaucoma of a young age, inherited disorders of connective tissue, juvenile glaucoma
目的。目的:探讨青光眼的诊断与治疗特点。材料和方法。10例青光眼青年患者的复杂眼科检查。其中保守治疗3例,其余行非穿透性深部巩膜切除术联合Xenoplast引流植入术。结果。接受手术治疗的患者,特别是青光眼早期患者,能够在稳定病理过程的同时,将视觉功能维持在较高水平。在一例近视和nNDST的未手术患者中,在最大限度的降压治疗下,根据oct发现阴性趋势。在唯一一例斜视患者中,药物治疗(前列腺素类似物)几年来指标稳定。结论。早期及时诊断和实施非穿透性深巩膜切除术是青光眼成功治疗的主要环节。轴型近视眼和青光眼患者应进行心脏学和骨科评估结缔组织损伤的迹象。未分化结缔组织发育不良可能是青光眼发病的病理生理基础。关键词:青光眼;结缔组织遗传性疾病;青光眼
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引用次数: 0
Clinical laboratory evaluation of the toxoplasmosis retinochorioiditis'diagnosis 弓形体病视网膜绒毛膜炎诊断的临床实验室评价
Pub Date : 2023-05-29 DOI: 10.25276/2312-4911-2023-2-330-336
M. A. Poroshina, M.A. Yunina, E. Pedanova
Purpose. To present OCT features of toxoplasmosis retinochorioiditis'diagnosis in patients with different immune status. Material and methods. The patients B. and K., male 44 and female 35 years old, with a decrease of visual acuity. The comprehensive ophthalmologic examinations ware carried out, including the examination of best corrected visual acuity (BCVA), slit lamp indirect ophthalmoscopy, microperimetry, optical coherence tomography (OCT), OCT – angiography, fundus autofluorescence (AF). Results. According to the anamnesis, clinical findings and OCT features the toxoplasmosis retinochorioiditis was diagnosed. Treatment was administrated with antibacterial drugs. Conclusions. Despite of the negative serology, the toxoplasmosis retinochorioididtis diagnosis was proved. It was diagnosed by the anamnesis, specific clinical findings and OCT features. Keywords: ocular toxoplasmosis, posterior uveitis, retinochorioiditis, optical coherence tomography
目的。探讨不同免疫状态下弓形虫病视网膜绒毛膜炎诊断的OCT特征。材料和方法。患者b、K,男44岁,女35岁,视力下降。进行了全面的眼科检查,包括最佳矫正视力检查(BCVA)、裂隙灯间接眼镜检查、显微视野检查、光学相干断层扫描(OCT)、OCT血管造影、眼底自体荧光(AF)检查。结果。根据患者的记忆、临床表现及OCT表现,诊断为弓形虫病视网膜绒毛膜炎。给予抗菌药物治疗。结论。尽管血清学阴性,但证实了视网膜绒毛膜炎的诊断。通过记忆、特殊临床表现和OCT特征进行诊断。关键词:眼弓形虫病,后葡萄膜炎,视网膜绒毛膜炎,光学相干断层扫描
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Modern technologies in ophtalmology
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