Pub Date : 2025-12-09DOI: 10.1038/s41577-025-01257-z
Yvonne Bordon
{"title":"Parental allergy and early life infection combine to promote asthma in childhood.","authors":"Yvonne Bordon","doi":"10.1038/s41577-025-01257-z","DOIUrl":"https://doi.org/10.1038/s41577-025-01257-z","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"17 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145710785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-08DOI: 10.1038/s41577-025-01259-x
Teresa Neuwirth,Barbara B Maier
{"title":"Type I interferon at the crossroads of metastatic dissemination.","authors":"Teresa Neuwirth,Barbara B Maier","doi":"10.1038/s41577-025-01259-x","DOIUrl":"https://doi.org/10.1038/s41577-025-01259-x","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"6 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145704663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1038/s41577-025-01251-5
Ezekiel Olumuyide, Robert Samstein
{"title":"Somatic mutations in T cells promote antitumour response","authors":"Ezekiel Olumuyide, Robert Samstein","doi":"10.1038/s41577-025-01251-5","DOIUrl":"https://doi.org/10.1038/s41577-025-01251-5","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"171 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145599440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1038/s41577-025-01253-3
Mehdi Chaib, James P. Allison
{"title":"Local Treg cell loss reprogrammes systemic antitumour immunity without breaking tolerance","authors":"Mehdi Chaib, James P. Allison","doi":"10.1038/s41577-025-01253-3","DOIUrl":"https://doi.org/10.1038/s41577-025-01253-3","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"7 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145609481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-26DOI: 10.1038/s41577-025-01252-4
Meredith Ramba, Dusan Bogunovic
{"title":"Targeting autoreactive B cells in SLE with anti-9G4 synthetic immune receptor T cells","authors":"Meredith Ramba, Dusan Bogunovic","doi":"10.1038/s41577-025-01252-4","DOIUrl":"https://doi.org/10.1038/s41577-025-01252-4","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"368 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145599441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-18DOI: 10.1038/s41577-025-01238-2
David Masopust, Amit Awasthi, Rémy Bosselut, David G. Brooks, Marcus Buggert, Kenji Chamoto, Weiguo Cui, Chen Dong, Donna L. Farber, Thomas Gebhardt, Carmen Gerlach, Ananda Goldrath, Philip D. Greenberg, J. Scott Hale, Adrian Hayday, Dirk Homann, Matteo Iannacone, Stephen C. Jameson, Marc K. Jenkins, Nikhil S. Joshi, Susan M. Kaech, Axel Kallies, Alice O. Kamphorst, Mark H. Kaplan, Paul Klenerman, Marco Künzli, Antonio Lanzavecchia, Georg M. Lauer, Enrico Lugli, Andrew D. Luster, Laura K. Mackay, M. Juliana McElrath, Scott N. Mueller, Zaza Ndhlovu, Thumbi Ndung’u, Pamela S. Ohashi, Annette Oxenius, Giuseppe Pantaleo, Marion Pepper, Louis J. Picker, Clare F. Quarnstrom, Gustavo Reyes-Terán, Mario Roederer, Pamela C. Rosato, Gonzalo Salgado-Montes de Oca, Federica Sallusto, Ton N. Schumacher, Daniella M. Schwartz, Eui-Cheol Shin, Andrew G. Soerens, Daniela S. Thommen, Vaiva Vezys, João P. B. Viola, Bruce D. Walker, Tania H. Watts, Casey T. Weaver, E. John Wherry, Hai-Hui Xue, Ben Youngblood, Rafi Ahmed
{"title":"Guidelines for T cell nomenclature","authors":"David Masopust, Amit Awasthi, Rémy Bosselut, David G. Brooks, Marcus Buggert, Kenji Chamoto, Weiguo Cui, Chen Dong, Donna L. Farber, Thomas Gebhardt, Carmen Gerlach, Ananda Goldrath, Philip D. Greenberg, J. Scott Hale, Adrian Hayday, Dirk Homann, Matteo Iannacone, Stephen C. Jameson, Marc K. Jenkins, Nikhil S. Joshi, Susan M. Kaech, Axel Kallies, Alice O. Kamphorst, Mark H. Kaplan, Paul Klenerman, Marco Künzli, Antonio Lanzavecchia, Georg M. Lauer, Enrico Lugli, Andrew D. Luster, Laura K. Mackay, M. Juliana McElrath, Scott N. Mueller, Zaza Ndhlovu, Thumbi Ndung’u, Pamela S. Ohashi, Annette Oxenius, Giuseppe Pantaleo, Marion Pepper, Louis J. Picker, Clare F. Quarnstrom, Gustavo Reyes-Terán, Mario Roederer, Pamela C. Rosato, Gonzalo Salgado-Montes de Oca, Federica Sallusto, Ton N. Schumacher, Daniella M. Schwartz, Eui-Cheol Shin, Andrew G. Soerens, Daniela S. Thommen, Vaiva Vezys, João P. B. Viola, Bruce D. Walker, Tania H. Watts, Casey T. Weaver, E. John Wherry, Hai-Hui Xue, Ben Youngblood, Rafi Ahmed","doi":"10.1038/s41577-025-01238-2","DOIUrl":"https://doi.org/10.1038/s41577-025-01238-2","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"3 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145536189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-18DOI: 10.1038/s41577-025-01246-2
David Masopust, Andrew G. Soerens, Clare F. Quarnstrom, Rafi Ahmed
{"title":"T cell nomenclature: from subsets to modules","authors":"David Masopust, Andrew G. Soerens, Clare F. Quarnstrom, Rafi Ahmed","doi":"10.1038/s41577-025-01246-2","DOIUrl":"https://doi.org/10.1038/s41577-025-01246-2","url":null,"abstract":"","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"224 1","pages":""},"PeriodicalIF":100.3,"publicationDate":"2025-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145536187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1038/s41577-025-01245-3
Yvonne Bordon
Short-chain fatty acids generated by the gut microbiota can support T cell ‘stemness’ and lead to improved cancer immunotherapy outcomes.
肠道菌群产生的短链脂肪酸可以支持T细胞的“干性”，从而改善癌症免疫治疗的效果。
{"title":"Butyrate promotes T cell ‘stemness’ to support immunity to melanoma","authors":"Yvonne Bordon","doi":"10.1038/s41577-025-01245-3","DOIUrl":"10.1038/s41577-025-01245-3","url":null,"abstract":"Short-chain fatty acids generated by the gut microbiota can support T cell ‘stemness’ and lead to improved cancer immunotherapy outcomes.","PeriodicalId":19049,"journal":{"name":"Nature Reviews Immunology","volume":"25 12","pages":"865-865"},"PeriodicalIF":60.9,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145509024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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