Pub Date : 2026-01-17DOI: 10.1016/j.ophtha.2026.01.009
Richard Kha, Andrew White, Shweta Kaushik, George Burlutsky, Gerald Liew, Paul Mitchell, Paul R. Healey, Anne Lee
PURPOSETo assess the 15-year cumulative incidence of open-angle glaucoma (OAG) in an older Australian population.DESIGNPopulation-based cohort study.PARTICIPANTS3654 Blue Mountains Eye Study participants from Australia, aged 49-97 years were examined during 1992-1994. Of these, 2335 (75.8% of survivors) were re-examined after 5 years (1997-1999), 1952 (76.7% of survivors) after 10 years (2002-2004), and 1149 (56.1% of survivors) after 15 years (2007-2010).METHODSGoldmann applanation tonometry, stereoscopic optic disc photography and automated perimetry were performed at baseline and follow-up studies. Glaucoma suspects returned for perimetry, gonioscopy and repeat perimetry and tonometry. After excluding persons with OAG at baseline, incident definite OAG was diagnosed when glaucomatous optic disc changes were congruous with visual field defects at any follow-up study. Incident probable OAG included participants with structural glaucomatous optic disc changes with inconsistent visual field loss. Cumulative and age-standardised incidence rates were estimated using Kaplan-Meier estimates.MAIN OUTCOME MEASURESCumulative and age-standardised 15-year incidence of definite and probable OAG, and associated risk factors.RESULTSIncident definite OAG developed in 116 subjects and probable OAG in 24 subjects, a total of 140 cases. The age-standardised 15-year incidence was 5.67% (95% confidence interval (CI): 4.65-6.68) for definite and probable OAG, and 4.72% (95% CI: 3.79-5.64) for definite OAG. After adjusting for competing risks, incidence of definite and probable OAG was 5.57% (95% CI: 4.66-6.47) and definite OAG was 4.81% (95% CI: 3.96-5.66). Age, pseudoexfoliation, myopia (≥3D) and IOP were strong risk factors for 15-year incidence of OAG.CONCLUSIONThis study documented the 15-year incidence of OAG and associated risk factors in an older Australian population. These data are useful for long term planning of glaucoma-related health services delivery.
{"title":"Fifteen-year Incidence of Open-Angle Glaucoma: the Blue Mountains Eye Study","authors":"Richard Kha, Andrew White, Shweta Kaushik, George Burlutsky, Gerald Liew, Paul Mitchell, Paul R. Healey, Anne Lee","doi":"10.1016/j.ophtha.2026.01.009","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.009","url":null,"abstract":"PURPOSETo assess the 15-year cumulative incidence of open-angle glaucoma (OAG) in an older Australian population.DESIGNPopulation-based cohort study.PARTICIPANTS3654 Blue Mountains Eye Study participants from Australia, aged 49-97 years were examined during 1992-1994. Of these, 2335 (75.8% of survivors) were re-examined after 5 years (1997-1999), 1952 (76.7% of survivors) after 10 years (2002-2004), and 1149 (56.1% of survivors) after 15 years (2007-2010).METHODSGoldmann applanation tonometry, stereoscopic optic disc photography and automated perimetry were performed at baseline and follow-up studies. Glaucoma suspects returned for perimetry, gonioscopy and repeat perimetry and tonometry. After excluding persons with OAG at baseline, incident definite OAG was diagnosed when glaucomatous optic disc changes were congruous with visual field defects at any follow-up study. Incident probable OAG included participants with structural glaucomatous optic disc changes with inconsistent visual field loss. Cumulative and age-standardised incidence rates were estimated using Kaplan-Meier estimates.MAIN OUTCOME MEASURESCumulative and age-standardised 15-year incidence of definite and probable OAG, and associated risk factors.RESULTSIncident definite OAG developed in 116 subjects and probable OAG in 24 subjects, a total of 140 cases. The age-standardised 15-year incidence was 5.67% (95% confidence interval (CI): 4.65-6.68) for definite and probable OAG, and 4.72% (95% CI: 3.79-5.64) for definite OAG. After adjusting for competing risks, incidence of definite and probable OAG was 5.57% (95% CI: 4.66-6.47) and definite OAG was 4.81% (95% CI: 3.96-5.66). Age, pseudoexfoliation, myopia (≥3D) and IOP were strong risk factors for 15-year incidence of OAG.CONCLUSIONThis study documented the 15-year incidence of OAG and associated risk factors in an older Australian population. These data are useful for long term planning of glaucoma-related health services delivery.","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"23 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145995267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.ophtha.2025.12.017
Risha Patel, Tatyana Milman, Paul D Langer
{"title":"Placoid Lesions in Eosinophilic Granulomatosis with Polyangiitis.","authors":"Risha Patel, Tatyana Milman, Paul D Langer","doi":"10.1016/j.ophtha.2025.12.017","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.12.017","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.ophtha.2025.12.020
Meghana Tanwar, Vedant Sharma, Usha Kim
{"title":"Ectopic Canine Tooth in the Superior Orbit.","authors":"Meghana Tanwar, Vedant Sharma, Usha Kim","doi":"10.1016/j.ophtha.2025.12.020","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.12.020","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.ophtha.2025.07.035
James O Robbins, Nathan T Tagg, Lejla Vajzovic
{"title":"Ocular Calciphylaxis in a 46-year-old Man on Hemodialysis.","authors":"James O Robbins, Nathan T Tagg, Lejla Vajzovic","doi":"10.1016/j.ophtha.2025.07.035","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.07.035","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1016/j.ophtha.2025.12.005
Rohun Yarala, Dhruv Manik, Susannah Rowe, Tomas Andersen
{"title":"Re: Tan et al.: Ophthalmic drop waste due to self-imposed use cessation dates (Ophthalmology. 2024;131:1345-1347).","authors":"Rohun Yarala, Dhruv Manik, Susannah Rowe, Tomas Andersen","doi":"10.1016/j.ophtha.2025.12.005","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.12.005","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-13DOI: 10.1016/j.ophtha.2025.12.006
Gareth M C Lema, David J Palmer, John M Tan, Paul A Sidoti, James C Tsai, Louis R Pasquale
{"title":"REPLY.","authors":"Gareth M C Lema, David J Palmer, John M Tan, Paul A Sidoti, James C Tsai, Louis R Pasquale","doi":"10.1016/j.ophtha.2025.12.006","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.12.006","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145959684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-12DOI: 10.1016/j.ophtha.2026.01.003
Wenjun Jiang PhD, Yuanyuan Hu MD PhD, Yanke Ai PhD, Ching-Yu Cheng MD PhD, Furu Xu MS, Liyun He MD PhD, Jike Song MD PhD, Yi Qu MD, Xun Xu MD, Jia Qu MD, Xuan Liao PhD, Mengjiao Diao MS, Tailiang Lu MD, Minglian Zhang MD, Longhui Han MD, Xiangdong Chen MD, Jiachao Yan MD, Wei Shi MD, Rui Guo MD, Yingxin Yang PhD, Chao Yang MS, Haiqiang Zhao MR, Jianfeng Wu MD, Dadong Guo PhD, Wei Sun PhD, Zhiyi Sun MS, Guangjun Wang MD, Baoyan Liu MD PhD, Mingguang He MD PhD, Hongsheng Bi MD PhD
The pre-myopia stage represents a critical window for early intervention and prevention, as myopia, once developed, is irreversible and associated with long-term visual complications. Our study aimed to evaluate the efficacy of eye‐transcutaneous electrical acupoint stimulation (ETEAS) in reducing myopia incidence in children with pre‐myopia.
{"title":"Effect of Eye-Transcutaneous Electrical Acupoint Stimulation on Myopia Incidence in Children: A Randomized Clinical Trial","authors":"Wenjun Jiang PhD, Yuanyuan Hu MD PhD, Yanke Ai PhD, Ching-Yu Cheng MD PhD, Furu Xu MS, Liyun He MD PhD, Jike Song MD PhD, Yi Qu MD, Xun Xu MD, Jia Qu MD, Xuan Liao PhD, Mengjiao Diao MS, Tailiang Lu MD, Minglian Zhang MD, Longhui Han MD, Xiangdong Chen MD, Jiachao Yan MD, Wei Shi MD, Rui Guo MD, Yingxin Yang PhD, Chao Yang MS, Haiqiang Zhao MR, Jianfeng Wu MD, Dadong Guo PhD, Wei Sun PhD, Zhiyi Sun MS, Guangjun Wang MD, Baoyan Liu MD PhD, Mingguang He MD PhD, Hongsheng Bi MD PhD","doi":"10.1016/j.ophtha.2026.01.003","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.003","url":null,"abstract":"The pre-myopia stage represents a critical window for early intervention and prevention, as myopia, once developed, is irreversible and associated with long-term visual complications. Our study aimed to evaluate the efficacy of eye‐transcutaneous electrical acupoint stimulation (ETEAS) in reducing myopia incidence in children with pre‐myopia.","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"53 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145956637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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