Pub Date : 2026-02-03DOI: 10.1016/j.ophtha.2026.01.028
David Cui, Divya Srikumaran, Charles Li, Xuan Peng, Priya M. Mathews
{"title":"Current Indications and Outcomes of Penetrating Keratoplasty in the United States: An IRIS® Registry (Intelligent Research in Sight) Study","authors":"David Cui, Divya Srikumaran, Charles Li, Xuan Peng, Priya M. Mathews","doi":"10.1016/j.ophtha.2026.01.028","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.028","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"5 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-02DOI: 10.1016/j.ophtha.2026.01.030
Clément Germanese, Marjolaine Georges, Philippe Bonniaud, Karine Goueslard, Louis Arnould, Catherine Creuzot Garcher, Pierre-Henry Gabrielle
{"title":"Characterization of Retinal Microvascular Changes in Obstructive Sleep Apnea using Optical Coherence Tomography Angiography: Data from the ORNET Study","authors":"Clément Germanese, Marjolaine Georges, Philippe Bonniaud, Karine Goueslard, Louis Arnould, Catherine Creuzot Garcher, Pierre-Henry Gabrielle","doi":"10.1016/j.ophtha.2026.01.030","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.030","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"195 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-23DOI: 10.1016/j.ophtha.2026.01.017
Xuesen Cheng, Francisco Mendes, Kusona Fortingo, Jay M. Jaber, Allison Chen, Mitchell P. Weikert, Li Wang, Douglas D. Koch
{"title":"A new intraocular-lens-power calculation formula for eyes undergoing lens exchange","authors":"Xuesen Cheng, Francisco Mendes, Kusona Fortingo, Jay M. Jaber, Allison Chen, Mitchell P. Weikert, Li Wang, Douglas D. Koch","doi":"10.1016/j.ophtha.2026.01.017","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.017","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"268 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146032816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-22DOI: 10.1016/j.ophtha.2026.01.013
Jaffer Shah, Peyman Razavi, Muhamad Festok, Harris Ahmed, M.Abdallah Mahrous, Kyle D. Kovacs, Szilárd Kiss
{"title":"Tirzepatide and Reduced Risk of Diabetic Retinopathy and Related Complications: A Multicenter U.S. Cohort Study","authors":"Jaffer Shah, Peyman Razavi, Muhamad Festok, Harris Ahmed, M.Abdallah Mahrous, Kyle D. Kovacs, Szilárd Kiss","doi":"10.1016/j.ophtha.2026.01.013","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.013","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"85 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146032819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-21DOI: 10.1016/j.ophtha.2026.01.018
Robert N. Weinreb, Pearse A. Keane, Andrea Cooley, Michael Chaglasian, Aaron Y. Lee, Michael V. McConnell, Theodore Leng, Zohre Hashemi, Daniela Ferrara, David Rhew
{"title":"A Framework for Healthcare from the Eye: Oculomics as a Powerful Window to Systemic Health","authors":"Robert N. Weinreb, Pearse A. Keane, Andrea Cooley, Michael Chaglasian, Aaron Y. Lee, Michael V. McConnell, Theodore Leng, Zohre Hashemi, Daniela Ferrara, David Rhew","doi":"10.1016/j.ophtha.2026.01.018","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.018","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"396 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-21DOI: 10.1016/j.ophtha.2025.11.011
Marcony R. Santhiago, W. Allan Steigleman, Zaina N. Al-Mohtaseb, Omar E. Awad, Kathryn Hatch, Joann J. Kang, Irene C. Kuo, Charles C. Lin, Seth M. Pantanelli, Leejee H. Suh, Jennifer R. Rose-Nussbaumer, Tiarnán D.L. Keenan, Julie M. Schallhorn, Stephen J. Kim, Deborah S. Jacobs
{"title":"LASIK for Hyperopia","authors":"Marcony R. Santhiago, W. Allan Steigleman, Zaina N. Al-Mohtaseb, Omar E. Awad, Kathryn Hatch, Joann J. Kang, Irene C. Kuo, Charles C. Lin, Seth M. Pantanelli, Leejee H. Suh, Jennifer R. Rose-Nussbaumer, Tiarnán D.L. Keenan, Julie M. Schallhorn, Stephen J. Kim, Deborah S. Jacobs","doi":"10.1016/j.ophtha.2025.11.011","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.11.011","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"185 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146014640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-17DOI: 10.1016/j.ophtha.2026.01.009
Richard Kha, Andrew White, Shweta Kaushik, George Burlutsky, Gerald Liew, Paul Mitchell, Paul R. Healey, Anne Lee
PURPOSETo assess the 15-year cumulative incidence of open-angle glaucoma (OAG) in an older Australian population.DESIGNPopulation-based cohort study.PARTICIPANTS3654 Blue Mountains Eye Study participants from Australia, aged 49-97 years were examined during 1992-1994. Of these, 2335 (75.8% of survivors) were re-examined after 5 years (1997-1999), 1952 (76.7% of survivors) after 10 years (2002-2004), and 1149 (56.1% of survivors) after 15 years (2007-2010).METHODSGoldmann applanation tonometry, stereoscopic optic disc photography and automated perimetry were performed at baseline and follow-up studies. Glaucoma suspects returned for perimetry, gonioscopy and repeat perimetry and tonometry. After excluding persons with OAG at baseline, incident definite OAG was diagnosed when glaucomatous optic disc changes were congruous with visual field defects at any follow-up study. Incident probable OAG included participants with structural glaucomatous optic disc changes with inconsistent visual field loss. Cumulative and age-standardised incidence rates were estimated using Kaplan-Meier estimates.MAIN OUTCOME MEASURESCumulative and age-standardised 15-year incidence of definite and probable OAG, and associated risk factors.RESULTSIncident definite OAG developed in 116 subjects and probable OAG in 24 subjects, a total of 140 cases. The age-standardised 15-year incidence was 5.67% (95% confidence interval (CI): 4.65-6.68) for definite and probable OAG, and 4.72% (95% CI: 3.79-5.64) for definite OAG. After adjusting for competing risks, incidence of definite and probable OAG was 5.57% (95% CI: 4.66-6.47) and definite OAG was 4.81% (95% CI: 3.96-5.66). Age, pseudoexfoliation, myopia (≥3D) and IOP were strong risk factors for 15-year incidence of OAG.CONCLUSIONThis study documented the 15-year incidence of OAG and associated risk factors in an older Australian population. These data are useful for long term planning of glaucoma-related health services delivery.
{"title":"Fifteen-year Incidence of Open-Angle Glaucoma: the Blue Mountains Eye Study","authors":"Richard Kha, Andrew White, Shweta Kaushik, George Burlutsky, Gerald Liew, Paul Mitchell, Paul R. Healey, Anne Lee","doi":"10.1016/j.ophtha.2026.01.009","DOIUrl":"https://doi.org/10.1016/j.ophtha.2026.01.009","url":null,"abstract":"PURPOSETo assess the 15-year cumulative incidence of open-angle glaucoma (OAG) in an older Australian population.DESIGNPopulation-based cohort study.PARTICIPANTS3654 Blue Mountains Eye Study participants from Australia, aged 49-97 years were examined during 1992-1994. Of these, 2335 (75.8% of survivors) were re-examined after 5 years (1997-1999), 1952 (76.7% of survivors) after 10 years (2002-2004), and 1149 (56.1% of survivors) after 15 years (2007-2010).METHODSGoldmann applanation tonometry, stereoscopic optic disc photography and automated perimetry were performed at baseline and follow-up studies. Glaucoma suspects returned for perimetry, gonioscopy and repeat perimetry and tonometry. After excluding persons with OAG at baseline, incident definite OAG was diagnosed when glaucomatous optic disc changes were congruous with visual field defects at any follow-up study. Incident probable OAG included participants with structural glaucomatous optic disc changes with inconsistent visual field loss. Cumulative and age-standardised incidence rates were estimated using Kaplan-Meier estimates.MAIN OUTCOME MEASURESCumulative and age-standardised 15-year incidence of definite and probable OAG, and associated risk factors.RESULTSIncident definite OAG developed in 116 subjects and probable OAG in 24 subjects, a total of 140 cases. The age-standardised 15-year incidence was 5.67% (95% confidence interval (CI): 4.65-6.68) for definite and probable OAG, and 4.72% (95% CI: 3.79-5.64) for definite OAG. After adjusting for competing risks, incidence of definite and probable OAG was 5.57% (95% CI: 4.66-6.47) and definite OAG was 4.81% (95% CI: 3.96-5.66). Age, pseudoexfoliation, myopia (≥3D) and IOP were strong risk factors for 15-year incidence of OAG.CONCLUSIONThis study documented the 15-year incidence of OAG and associated risk factors in an older Australian population. These data are useful for long term planning of glaucoma-related health services delivery.","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":"23 1","pages":""},"PeriodicalIF":13.7,"publicationDate":"2026-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145995267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-16DOI: 10.1016/j.ophtha.2025.12.017
Risha Patel, Tatyana Milman, Paul D Langer
{"title":"Placoid Lesions in Eosinophilic Granulomatosis with Polyangiitis.","authors":"Risha Patel, Tatyana Milman, Paul D Langer","doi":"10.1016/j.ophtha.2025.12.017","DOIUrl":"https://doi.org/10.1016/j.ophtha.2025.12.017","url":null,"abstract":"","PeriodicalId":19533,"journal":{"name":"Ophthalmology","volume":" ","pages":""},"PeriodicalIF":9.5,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145990354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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