Pub Date : 2023-04-22DOI: 10.3889/oamjms.2023.11624
Made Asmara Yoga, Ketut Siki Kawiyana, Made Bramantya Karna
BACKGROUND: Distal radius fractures are the most common upper extremity fractures with a prevalence of 20% of all limb fractures. According to the distal radius fracture guidelines by the American Academy of orthopedic surgeons, conservative therapy can be used in the management of distal radius fractures that are well reduced. AIM: The purpose of this study was to compare conservative therapy of short arm cast (SAC) and long arm cast (LAC) in the management of intraarticular distal radius fractures. METHODS: A prospective cohort observational study with consecutive sampling was conducted on 24 intraarticular distal fracture patients who underwent SAC and LAC procedures. The parameters measured were Interleukin-6 (IL-6) score, ulnar variance (UV), dorsal tilt (DT), articular step-off (SO), radiological union score system (RUSS), and patient-rated wrist evaluation (PRWE) score. RESULTS: The dominance of patients was males aged 46 years, with an average IL-6 levels at 0–24 was 1139.23 ± 266.82 SAC and 1082.64 ± 255.85 LAC, and IL-6 levels at 48 h was 102.98 ± 39.31 SAC and 118.38 ± 39.15 LAC; 2 patients with SAC and 1 patient with LAC obtained unacceptable reduction at week 2 based on UV, DT, SO which did not differ significantly from each follow-up; RUSS 6.08 ± 0.76 SAC and 5.71 ± 0.61 LAC; and PRWE 73.23 ± 4.42 SAC and 71.86 ± 4.07 LAC. Based on statistical analysis, there were insignificant differences in IL-6, UV, DT, SO, RUSS, and PRWE levels between the SAC and LAC groups (p > 0.05). CONCLUSION: Conservative therapy with SAC may be an option for immobilization of distal radius fracture similar to LAC.
{"title":"Differences in Inflammation, Radiological and Clinical Outcomes between Short Arm Cast and Long Arm Cast in Intraarticular Distal Radius Fractures","authors":"Made Asmara Yoga, Ketut Siki Kawiyana, Made Bramantya Karna","doi":"10.3889/oamjms.2023.11624","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11624","url":null,"abstract":"BACKGROUND: Distal radius fractures are the most common upper extremity fractures with a prevalence of 20% of all limb fractures. According to the distal radius fracture guidelines by the American Academy of orthopedic surgeons, conservative therapy can be used in the management of distal radius fractures that are well reduced. AIM: The purpose of this study was to compare conservative therapy of short arm cast (SAC) and long arm cast (LAC) in the management of intraarticular distal radius fractures. METHODS: A prospective cohort observational study with consecutive sampling was conducted on 24 intraarticular distal fracture patients who underwent SAC and LAC procedures. The parameters measured were Interleukin-6 (IL-6) score, ulnar variance (UV), dorsal tilt (DT), articular step-off (SO), radiological union score system (RUSS), and patient-rated wrist evaluation (PRWE) score. RESULTS: The dominance of patients was males aged 46 years, with an average IL-6 levels at 0–24 was 1139.23 ± 266.82 SAC and 1082.64 ± 255.85 LAC, and IL-6 levels at 48 h was 102.98 ± 39.31 SAC and 118.38 ± 39.15 LAC; 2 patients with SAC and 1 patient with LAC obtained unacceptable reduction at week 2 based on UV, DT, SO which did not differ significantly from each follow-up; RUSS 6.08 ± 0.76 SAC and 5.71 ± 0.61 LAC; and PRWE 73.23 ± 4.42 SAC and 71.86 ± 4.07 LAC. Based on statistical analysis, there were insignificant differences in IL-6, UV, DT, SO, RUSS, and PRWE levels between the SAC and LAC groups (p > 0.05). CONCLUSION: Conservative therapy with SAC may be an option for immobilization of distal radius fracture similar to LAC.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135415182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-20DOI: 10.3889/oamjms.2023.11599
I. Nyoman, Yuda Raditya, K. G. M. Ridia, I. W. Aryana, Ni Nengah, Dwi Fatmawati, I. Suyasa, Ksenija Bogoeva-Kostovska
BACKGROUND: An open fracture is an emergency case that must be treated quickly to prevent infection. The use of an irrigation solution containing 0.1% of the antimicrobial polyhexanide and 0.1% of the surfactant betaine has been associated with more satisfactory wound healing. AIM: This study was comparing irrigation with polyhexanide 0.1% and betaine 0.1% (P + B) in reducing bacterial colonization of open fractures compared to using 0.9% natrium chloride (NaCl) solution. METHODS: This study uses a pre- and post-control group design. Sampling was carried out in the operation room of the emergency care installation, inpatient installation, and outpatient installation of prof. Hospital. Dr. I.G.N.G Ngoerah Denpasar, between September and November 2022. From a sample population suffering from open fractures of the lower extremities, samples of patients were taken who were irrigated with 0.9% NaCl solution with a mixture of polyhexanide 0.1% and betaine 0.1%. The presence or absence of bacterial colonization was examined using a surgical wound base swab with the Levine technique. RESULTS: In the 30 patients in this study, there was a significant decrease in bacterial levels (Log colony-forming unit [CFU]/g) after irrigation, both from irrigation with NaCl (p = 0.04) and NaCl + P + B (p < 0.001). The reduction in bacterial levels was more significant with NaCl + P + B compared with NaCl alone, at post-irrigation (p < 0.001), H+3 (p = 0.003), and H + 7 (p < 0.001). CONCLUSION: Wound irrigation using a combination of 0.9% NaCl, 0.1% polyhexanide, and 0.1% betaine reduced bacterial colonization more than using 0.9% NaCl-only solution in open fractures of long bones.
{"title":"Differences in Decreasing Bacteria Colonization Wound Irrigation using 0.9% Nacl Compared with Wound Irrigation using Active Ingredients Polyhexanide 0.1% and 0.1% Betaine in Open Fractures of Long Bone","authors":"I. Nyoman, Yuda Raditya, K. G. M. Ridia, I. W. Aryana, Ni Nengah, Dwi Fatmawati, I. Suyasa, Ksenija Bogoeva-Kostovska","doi":"10.3889/oamjms.2023.11599","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11599","url":null,"abstract":"BACKGROUND: An open fracture is an emergency case that must be treated quickly to prevent infection. The use of an irrigation solution containing 0.1% of the antimicrobial polyhexanide and 0.1% of the surfactant betaine has been associated with more satisfactory wound healing.\u0000AIM: This study was comparing irrigation with polyhexanide 0.1% and betaine 0.1% (P + B) in reducing bacterial colonization of open fractures compared to using 0.9% natrium chloride (NaCl) solution.\u0000METHODS: This study uses a pre- and post-control group design. Sampling was carried out in the operation room of the emergency care installation, inpatient installation, and outpatient installation of prof. Hospital. Dr. I.G.N.G Ngoerah Denpasar, between September and November 2022. From a sample population suffering from open fractures of the lower extremities, samples of patients were taken who were irrigated with 0.9% NaCl solution with a mixture of polyhexanide 0.1% and betaine 0.1%. The presence or absence of bacterial colonization was examined using a surgical wound base swab with the Levine technique.\u0000RESULTS: In the 30 patients in this study, there was a significant decrease in bacterial levels (Log colony-forming unit [CFU]/g) after irrigation, both from irrigation with NaCl (p = 0.04) and NaCl + P + B (p < 0.001). The reduction in bacterial levels was more significant with NaCl + P + B compared with NaCl alone, at post-irrigation (p < 0.001), H+3 (p = 0.003), and H + 7 (p < 0.001).\u0000CONCLUSION: Wound irrigation using a combination of 0.9% NaCl, 0.1% polyhexanide, and 0.1% betaine reduced bacterial colonization more than using 0.9% NaCl-only solution in open fractures of long bones.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46089813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUND: Cardiac disease is the number one cause of death in the world, including in Indonesia. According to the 2018 Riskesdas data, the prevalence of cardiac disease in Indonesian society based on doctor’s diagnosis is 1.5%. This means that out of one hundred Indonesians, 1.5 people suffer from cardiac disease. AIM: The aim of this study was to determine the relationship between smoking habits, physical activity, and drinking alcohol with the cardiac disease in Indonesia. METHODS: This is a further data analysis of BASIC Health Research 2018, a national cross-sectional study in Indonesia. The research samples were all members in selected households. The samples analyzed were household members aged 10 years and over. The data were collected through interview using a structured questionnaire. The analysis was done using the Chi-square and multivariate logistic regression methods with complex sample approach. RESULTS: The results showed that the characteristics of the respondents, which were age, gender, education, occupation, and place of residence, had a significant relationship with cardiac disease (p < 0.001). Smoking habits, physical activity, and drinking alcohol also had a significant relationship with cardiac disease (p < 0.001). The results of the multivariate test showed that smoking habits and lack of physical activity were the factors that most influence the incidence of cardiovascular disease (p < 0.001). CONCLUSION: Smoking habits, physical activity, and drinking alcohol are significantly associated with the cardiac disease in people aged 10 years and over in Indonesia.
{"title":"The Relationship between Smoking Habits, Physical Activity, and Drinking Alcohol with Cardiac Disease: A Cross-sectional Study","authors":"Made Ayu Lely Suratri, Vivi Setiawaty, Noer Endah Pracoyo, Delima Delima, Raharni Raharni, Rudi Hendro Putranto, Nurhayati Nurhayati, Telly Purnamasari Agus, Aris Yulianto, Anni Yulianti","doi":"10.3889/oamjms.2023.11615","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11615","url":null,"abstract":"BACKGROUND: Cardiac disease is the number one cause of death in the world, including in Indonesia. According to the 2018 Riskesdas data, the prevalence of cardiac disease in Indonesian society based on doctor’s diagnosis is 1.5%. This means that out of one hundred Indonesians, 1.5 people suffer from cardiac disease. AIM: The aim of this study was to determine the relationship between smoking habits, physical activity, and drinking alcohol with the cardiac disease in Indonesia. METHODS: This is a further data analysis of BASIC Health Research 2018, a national cross-sectional study in Indonesia. The research samples were all members in selected households. The samples analyzed were household members aged 10 years and over. The data were collected through interview using a structured questionnaire. The analysis was done using the Chi-square and multivariate logistic regression methods with complex sample approach. RESULTS: The results showed that the characteristics of the respondents, which were age, gender, education, occupation, and place of residence, had a significant relationship with cardiac disease (p < 0.001). Smoking habits, physical activity, and drinking alcohol also had a significant relationship with cardiac disease (p < 0.001). The results of the multivariate test showed that smoking habits and lack of physical activity were the factors that most influence the incidence of cardiovascular disease (p < 0.001). CONCLUSION: Smoking habits, physical activity, and drinking alcohol are significantly associated with the cardiac disease in people aged 10 years and over in Indonesia.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136244422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-14DOI: 10.3889/oamjms.2023.11611
Maria Yasintha Lihawa, E. A. Datau, E. Surachmanto, J. Soekarno, Budi Tulaka
BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic has been going on for more than 2 years, with various treatments and diagnostic methods available. One of the most prized structures, the receptor-binding domain (RBD) of the spike protein in severe acute respiratory syndrome coronavirus 2 has long been thoroughly researched for its function and becoming the target for various diagnostic methods and treatments, including a vaccine. The spike-RBD (sRBD) antibody count might be the parameter for antibody response in vaccinated and infected individuals. However, no direct comparison is made. AIM: The study aims to compare the sRBD antibody count in the naturally infected individuals to the vaccinated ones. METHODS: We conducted a cross-sectional study with 49 participants of the infected patients, and vaccinated individuals were included in this study from Prof. Dr. R. D. Kandou Hospital, Manado. The participants underwent a COVID-19 antibody test, using enhanced “Chemiluminescence” Immuno assay to analyze the anti-sRBD IgG quantitatively. Results were then analyzed and compared using IBM Statistical Package for Social Sciences ver 25.0 with Mann−Whitney non-parametric test. RESULTS: The study shows a higher median antibody count in the naturally infected group compared to the vaccinated group (132.70 vs. 11.95 U/mL; p < 0.001). Further studies on the topic should be conducted to determine the comparison on a larger scale. CONCLUSION: The s-RBD antibody titer is significantly higher in naturally infected patients than in vaccinated individuals.
{"title":"Quantitative SARS-CoV-2 Spike Receptor-Binding Domain on Vaccinated Individuals Compared to Natural Infection","authors":"Maria Yasintha Lihawa, E. A. Datau, E. Surachmanto, J. Soekarno, Budi Tulaka","doi":"10.3889/oamjms.2023.11611","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11611","url":null,"abstract":"BACKGROUND: Coronavirus disease 2019 (COVID-19) pandemic has been going on for more than 2 years, with various treatments and diagnostic methods available. One of the most prized structures, the receptor-binding domain (RBD) of the spike protein in severe acute respiratory syndrome coronavirus 2 has long been thoroughly researched for its function and becoming the target for various diagnostic methods and treatments, including a vaccine. The spike-RBD (sRBD) antibody count might be the parameter for antibody response in vaccinated and infected individuals. However, no direct comparison is made.\u0000AIM: The study aims to compare the sRBD antibody count in the naturally infected individuals to the vaccinated ones.\u0000METHODS: We conducted a cross-sectional study with 49 participants of the infected patients, and vaccinated individuals were included in this study from Prof. Dr. R. D. Kandou Hospital, Manado. The participants underwent a COVID-19 antibody test, using enhanced “Chemiluminescence” Immuno assay to analyze the anti-sRBD IgG quantitatively. Results were then analyzed and compared using IBM Statistical Package for Social Sciences ver 25.0 with Mann−Whitney non-parametric test.\u0000RESULTS: The study shows a higher median antibody count in the naturally infected group compared to the vaccinated group (132.70 vs. 11.95 U/mL; p < 0.001). Further studies on the topic should be conducted to determine the comparison on a larger scale.\u0000CONCLUSION: The s-RBD antibody titer is significantly higher in naturally infected patients than in vaccinated individuals.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42746347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-14DOI: 10.3889/oamjms.2023.11160
Mustika Marwah, B. Wispriyono, D. Susanna, A. Kusuma, Eli Djulejic
BACKGROUND:Coronavirus disease 2019 (COVID-19) is thought to be transmitted primarily through droplets and contaminated surfaces through aerosols. AIM: Therefore, this study aims to identify the risk of COVID-19 agents in aerosol form and how indoor air control technique plays a role in the risk of disease transmission. It also examines the existing policies as administrative controls in managing the risk of COVID-19 transmission through indoor air control techniques. METHODS: This is a systematic review and policy study carried out in line with the preferred reporting item for systematic review and meta-analysis guidelines using ProQuest, PubMed, ScienceDirect, and Scopus databases. Furthermore, the search strategy was carried out using keywords with the Boolean AND and OR operations, namely, “COVID-19 AND (Transmission OR Spread) AND (aerosol OR airborne OR microdroplet) AND (Indoor OR Indoor Air OR Ventilation). RESULTS: In the policy review, the analysis unit was obtained from the official websites of the Indonesian Government and World Health Organization in the form of regulations, recommendations, guidelines, or other protocols that regulate indoor activities during the pandemic. There is a risk of COVID-19 agents from aerosols in indoor air. Meanwhile, the control of indoor air techniques plays a role in reducing the risk of transmission through aerosols by (1) increasing the exchange of indoor with outdoor air, (2) using air purifiers, and (3) paying attention to the layout of ventilation devices, airflow direction and distribution, as well as the flow of clean and dirty air in a room. CONCLUSION: Based on the results, the existing policies are still minimal in preventing transmission risk through indoor aerosols; hence, policy development is needed.
{"title":"Factors Affecting Indoor Air against the Transmission Risk of Coronavirus Disease 2019: Systematic Review and Policy Analysis","authors":"Mustika Marwah, B. Wispriyono, D. Susanna, A. Kusuma, Eli Djulejic","doi":"10.3889/oamjms.2023.11160","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11160","url":null,"abstract":"BACKGROUND:Coronavirus disease 2019 (COVID-19) is thought to be transmitted primarily through droplets and contaminated surfaces through aerosols.\u0000AIM: Therefore, this study aims to identify the risk of COVID-19 agents in aerosol form and how indoor air control technique plays a role in the risk of disease transmission. It also examines the existing policies as administrative controls in managing the risk of COVID-19 transmission through indoor air control techniques.\u0000METHODS: This is a systematic review and policy study carried out in line with the preferred reporting item for systematic review and meta-analysis guidelines using ProQuest, PubMed, ScienceDirect, and Scopus databases. Furthermore, the search strategy was carried out using keywords with the Boolean AND and OR operations, namely, “COVID-19 AND (Transmission OR Spread) AND (aerosol OR airborne OR microdroplet) AND (Indoor OR Indoor Air OR Ventilation).\u0000RESULTS: In the policy review, the analysis unit was obtained from the official websites of the Indonesian Government and World Health Organization in the form of regulations, recommendations, guidelines, or other protocols that regulate indoor activities during the pandemic. There is a risk of COVID-19 agents from aerosols in indoor air. Meanwhile, the control of indoor air techniques plays a role in reducing the risk of transmission through aerosols by (1) increasing the exchange of indoor with outdoor air, (2) using air purifiers, and (3) paying attention to the layout of ventilation devices, airflow direction and distribution, as well as the flow of clean and dirty air in a room.\u0000CONCLUSION: Based on the results, the existing policies are still minimal in preventing transmission risk through indoor aerosols; hence, policy development is needed.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41447028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-14DOI: 10.3889/oamjms.2023.11595
Septa Katmawanti, Muhammad Al-Irsyad, Anita Sulistyorini, Siti Khuzaimah A. Sharoni, Dea Aflah Samah, Purnama Devita Sari, Aquila Ghafriel Azizah, Yuanda Putri Rizki Ramadhani
BACKGROUND: The increase in dengue cases in the coronavirus disease (COVID-19) pandemic is affected by restrictions on human movement, climate, human behavior, and knowledge. Animated film for communication media based on digital technology as a promotional and preventive tool regarding dengue hemorrhagic fever (DHF) in the era of the COVID-19 pandemic. AIM: The purpose of this study is to increase knowledge and attitudes among productive-age youth as part of efforts to prevent DHF cases during the COVID-19 pandemic and in the future. METHODS: A pre-experimental study design with a one-group pre-test and post-test design was used in this study, so only one group was studied. In this study, using total sampling, as many as 30 respondents from the total population who are Grade 1 students at one of the junior high schools in Malang City. RESULTS: The difference test on knowledge produced an asymptotic sig value of 0.000, which is (<0.05). This means that the average post-test score obtained is higher and significantly different from the pre-test. In addition, based on the results of the difference test on attitudes, an Asymp Sig value of 0.001 is obtained, which is (<0.05). This means that the average post-test score obtained is higher and significantly different from the pre-test. CONCLUSION: Animated films as digital-based socialization media can help increase students’ knowledge and attitudes in efforts to prevent DHF outbreaks.
{"title":"Utilization of Animated Films as Digital-based Socialization Media for Prevention of Dengue Hemorrhagic Fever Outbreaks in the Malang City Region during the COVID-19 Pandemic","authors":"Septa Katmawanti, Muhammad Al-Irsyad, Anita Sulistyorini, Siti Khuzaimah A. Sharoni, Dea Aflah Samah, Purnama Devita Sari, Aquila Ghafriel Azizah, Yuanda Putri Rizki Ramadhani","doi":"10.3889/oamjms.2023.11595","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11595","url":null,"abstract":"BACKGROUND: The increase in dengue cases in the coronavirus disease (COVID-19) pandemic is affected by restrictions on human movement, climate, human behavior, and knowledge. Animated film for communication media based on digital technology as a promotional and preventive tool regarding dengue hemorrhagic fever (DHF) in the era of the COVID-19 pandemic.\u0000AIM: The purpose of this study is to increase knowledge and attitudes among productive-age youth as part of efforts to prevent DHF cases during the COVID-19 pandemic and in the future.\u0000METHODS: A pre-experimental study design with a one-group pre-test and post-test design was used in this study, so only one group was studied. In this study, using total sampling, as many as 30 respondents from the total population who are Grade 1 students at one of the junior high schools in Malang City.\u0000RESULTS: The difference test on knowledge produced an asymptotic sig value of 0.000, which is (<0.05). This means that the average post-test score obtained is higher and significantly different from the pre-test. In addition, based on the results of the difference test on attitudes, an Asymp Sig value of 0.001 is obtained, which is (<0.05). This means that the average post-test score obtained is higher and significantly different from the pre-test.\u0000CONCLUSION: Animated films as digital-based socialization media can help increase students’ knowledge and attitudes in efforts to prevent DHF outbreaks.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135085876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-14DOI: 10.3889/oamjms.2023.11576
Maria Clarissa Wiraputranto, Irma Bernadette S. Sitohang, Windy Keumala Budianti, Adhimukti T. Sampurna
BACKGROUND: Acne vulgaris (AV) is an inflammatory disease of the pilosebaceous unit with various pleomorphic lesions. In Indonesia, AV is the third most common case that makes patients come to seek treatment at the Hospital. The diagnosis can be established clinically and the AV grading system can be used to assess the severity. Until now, there are many AV grading systems and guidelines for AV. At Dr. Cipto Mangunkusumo Hospital uses Lehmann’s grading system. AIM: The aims of this review were to summarize the current guidelines for AV therapy in Indonesia and assess the efficacy of various therapeutic regimens. METHODS: We conducted a comprehensive literature search using the search engines PubMed, Scopus, Research Gate, and Google Scholar in the time frame 2015 until 2022 with a total of 431 articles, and 29 studies met the inclusion criteria. The studies reported a total of 8245 participants. RESULTS AND DISCUSSION: AV management may differ according to the conditions of each country. There are two therapeutic modalities for AV medication management, topical and systemic. The choice of therapy must be adjusted to the patient’s needs, AV severity, and drug efficacy, taking into account the risk and benefit factors of the drug, as well as psychosocial factors. CONCLUSION: Management of AV is still a challenge because the therapy in different countries is not the same. It is necessary to know the etiopathogenesis, understand patient’s condition and the severity of AV, also know the efficacy of AV therapy, and consider treatment recommendations based on existing guidelines so that the treatment results can be achieved optimally.
{"title":"Acne Vulgaris Medicament Management in Indonesia and the Efficacy of Various Therapeutic Regimens","authors":"Maria Clarissa Wiraputranto, Irma Bernadette S. Sitohang, Windy Keumala Budianti, Adhimukti T. Sampurna","doi":"10.3889/oamjms.2023.11576","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11576","url":null,"abstract":"BACKGROUND: Acne vulgaris (AV) is an inflammatory disease of the pilosebaceous unit with various pleomorphic lesions. In Indonesia, AV is the third most common case that makes patients come to seek treatment at the Hospital. The diagnosis can be established clinically and the AV grading system can be used to assess the severity. Until now, there are many AV grading systems and guidelines for AV. At Dr. Cipto Mangunkusumo Hospital uses Lehmann’s grading system. AIM: The aims of this review were to summarize the current guidelines for AV therapy in Indonesia and assess the efficacy of various therapeutic regimens. METHODS: We conducted a comprehensive literature search using the search engines PubMed, Scopus, Research Gate, and Google Scholar in the time frame 2015 until 2022 with a total of 431 articles, and 29 studies met the inclusion criteria. The studies reported a total of 8245 participants. RESULTS AND DISCUSSION: AV management may differ according to the conditions of each country. There are two therapeutic modalities for AV medication management, topical and systemic. The choice of therapy must be adjusted to the patient’s needs, AV severity, and drug efficacy, taking into account the risk and benefit factors of the drug, as well as psychosocial factors. CONCLUSION: Management of AV is still a challenge because the therapy in different countries is not the same. It is necessary to know the etiopathogenesis, understand patient’s condition and the severity of AV, also know the efficacy of AV therapy, and consider treatment recommendations based on existing guidelines so that the treatment results can be achieved optimally.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":"36 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135085877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-13DOI: 10.3889/oamjms.2023.11569
C. Yanti, E. Susanti, Dina Ediana
BACKGROUND: Blood pressure may cause 7.5 million deaths and around 12.8% are deaths. The hypertension will continue and it is predicted in 2025, there are 29% of adults worldwide will be affected by hypertension. Based on data from Arosuka District Hospital in Solok, there were 133 (14.31%) patients with hypertension. AIM: The purpose of this research was to determine factors influence hypertension. METHODS: The type of this research was cross-sectional. The populations were all of hypertensive patients who visited the Arosuka District Hospital. They were 133 samples. They had been chosen using total sampling. Then, the data were analyzed by univariate and bivariate through Chi-square and multivariate tests with binary logistic regression. RESULTS: The results showed that the variables related to hypertension were age (elderly = 66.2%, p = 0.0001, OR = 0.107), gender (female = 63.9%, p = 0.0001, OR = 3.917), index body mass (overweight = 69.2%, p = 0.0001, OR = 4.451), exercise (not exercising = 57.9%, p = 0.020, OR = 2.296), smoking (not smoking = 63.9%, p = 0.0001, OR = 0.255), and heart disease (undiagnosed = 87.2%, p = 0.005, OR = 7.000). In short, the variable related to hypertension were age (p = 0.0001, OR = 0.114), body mass index (p = 0.032, OR = 2.737), and heart disease (p = 0.002, OR = 12.231). CONCLUSION: In conclusion, the most influential factor toward hypertension was heart disease. Prevention is done by having a heart-healthy diet, controlling blood pressure, maintaining a normal body weight, quitting smoking, and being diligent in doing physical activity.
{"title":"Modifiable and Unmodifiable Variable Analysis of Hypertension Incidence","authors":"C. Yanti, E. Susanti, Dina Ediana","doi":"10.3889/oamjms.2023.11569","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11569","url":null,"abstract":"BACKGROUND: Blood pressure may cause 7.5 million deaths and around 12.8% are deaths. The hypertension will continue and it is predicted in 2025, there are 29% of adults worldwide will be affected by hypertension. Based on data from Arosuka District Hospital in Solok, there were 133 (14.31%) patients with hypertension.\u0000AIM: The purpose of this research was to determine factors influence hypertension.\u0000METHODS: The type of this research was cross-sectional. The populations were all of hypertensive patients who visited the Arosuka District Hospital. They were 133 samples. They had been chosen using total sampling. Then, the data were analyzed by univariate and bivariate through Chi-square and multivariate tests with binary logistic regression.\u0000RESULTS: The results showed that the variables related to hypertension were age (elderly = 66.2%, p = 0.0001, OR = 0.107), gender (female = 63.9%, p = 0.0001, OR = 3.917), index body mass (overweight = 69.2%, p = 0.0001, OR = 4.451), exercise (not exercising = 57.9%, p = 0.020, OR = 2.296), smoking (not smoking = 63.9%, p = 0.0001, OR = 0.255), and heart disease (undiagnosed = 87.2%, p = 0.005, OR = 7.000). In short, the variable related to hypertension were age (p = 0.0001, OR = 0.114), body mass index (p = 0.032, OR = 2.737), and heart disease (p = 0.002, OR = 12.231).\u0000CONCLUSION: In conclusion, the most influential factor toward hypertension was heart disease. Prevention is done by having a heart-healthy diet, controlling blood pressure, maintaining a normal body weight, quitting smoking, and being diligent in doing physical activity.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45618396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-13DOI: 10.3889/oamjms.2023.11566
M. Qattan
Introduction: Non-Hodgkin’s lymphoma (NHL) consists of several hematologic malignancies arising from B, T lymphocytes or natural killer lymphocytes, and nearly 85–90% originates from B lymphocytes. This current study illustrates frequency of diagnosed NHL cases, age-standardized incidence rate (ASIR) and crude incidence rate (CIR) by age group, year of diagnosis and administrative regions for identifying the distribution, pattern and real condition of NHL in Saudi Arabia. Methodology: In this study, an epidemiological analysis of NHL cases is conducted on registered cases between 2006 and 2016 from Saudi cancer registry (SCR). For statistical analysis, t-test, sex ratio, Kruskal–Wallis and descriptive statistics were performed by SPSS version 20.0. Results: A total of 8019 NHL cases were documented from reported from January 2006 to December 2016. Among males, Riyadh region had the highest overall ASIR at 7.9 followed by Eastern region at 6.9 per 100,000 males and lowest overall ASIRs were observed in Jazan and Hail region at 3.5, and the Northern region at 3.9 per 100,000 males. The highest overall ASIR among females was reported in the Riyadh region at 6.9 and Eastern region at 5.2 per 100,000 females and lowest overall ASIR was documented in the Jazan region at 2.2, followed by Hail at 2.4. The overall age-standardized incidence sex ratio of NHL was found to be 1.3 per100,000 in Saudi Arabia. Conclusion: This study concluded an increase in crude incidence rates and age-standardized incidence rates NHL among Saudi population. Highest overall ASIRs for NHL among males and females from 2006 to 2016 were documented in Riyadh and Eastern region. While, lowest overall ASIRs among males and females were documented in the Jazan and Hail region.
{"title":"The Incidence Rate of Non-Hodgkin’s Lymphoma in Saudi Arabia: An Observational Descriptive Population Based Epidemiological Study from the Saudi Cancer Registry (2006–2016)","authors":"M. Qattan","doi":"10.3889/oamjms.2023.11566","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11566","url":null,"abstract":"Introduction: Non-Hodgkin’s lymphoma (NHL) consists of several hematologic malignancies arising from B, T lymphocytes or natural killer lymphocytes, and nearly 85–90% originates from B lymphocytes. This current study illustrates frequency of diagnosed NHL cases, age-standardized incidence rate (ASIR) and crude incidence rate (CIR) by age group, year of diagnosis and administrative regions for identifying the distribution, pattern and real condition of NHL in Saudi Arabia. \u0000Methodology: In this study, an epidemiological analysis of NHL cases is conducted on registered cases between 2006 and 2016 from Saudi cancer registry (SCR). For statistical analysis, t-test, sex ratio, Kruskal–Wallis and descriptive statistics were performed by SPSS version 20.0. \u0000Results: A total of 8019 NHL cases were documented from reported from January 2006 to December 2016. Among males, Riyadh region had the highest overall ASIR at 7.9 followed by Eastern region at 6.9 per 100,000 males and lowest overall ASIRs were observed in Jazan and Hail region at 3.5, and the Northern region at 3.9 per 100,000 males. The highest overall ASIR among females was reported in the Riyadh region at 6.9 and Eastern region at 5.2 per 100,000 females and lowest overall ASIR was documented in the Jazan region at 2.2, followed by Hail at 2.4. The overall age-standardized incidence sex ratio of NHL was found to be 1.3 per100,000 in Saudi Arabia. \u0000Conclusion: This study concluded an increase in crude incidence rates and age-standardized incidence rates NHL among Saudi population. Highest overall ASIRs for NHL among males and females from 2006 to 2016 were documented in Riyadh and Eastern region. While, lowest overall ASIRs among males and females were documented in the Jazan and Hail region.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47928911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-13DOI: 10.3889/oamjms.2023.11537
Lamya Mallasi, Fatimah A. Alsaeed, Dina M. D. Badr, S. Salama
Coronavirus disease is a serious viral infection that is characterized by severe inflammation and lymphopenia. The virus attacks many organs causing acute respiratory distress and malfunctioning of the organs leading to death. Through strengthening of the innate immune system, a balanced diet plays a critical role in defense against bacterial and viral diseases. A healthy diet before, during and after an infection can lessen the severity of the symptoms and speed up the recovery of damaged cells. Due to the Mediterranean diet’s high concentration of bioactive polyphenols, which have antioxidant, anti-inflammatory, and antithrombic properties, numerous studies have suggested that it is a preventative dietary strategy against many diseases including coronavirus disease. Nutrition and herbal plants play a key role to enhance the immunity of people to protect and fight against coronavirus. Diet rich in antioxidants and phytochemicals represents perfect barrier to the virus through elevation of the innate immunity of the body. In addition, gut microbiota including prebiotics, probiotics, and synbiotics were found to enhance immunity to reduce the symptoms of the disease during infection. Protein-rich foods and honey bee products reported significant role during and post-coronavirus infection. This review presents updated information from original pre-clinical and clinical researches, and review articles as well to expose the nutritive strategies including breastfeeding benefits to infants pre-infection, during, and post-infection with coronavirus.
{"title":"Nutrition Strategies Pre-infection, during, and Post-infection with Coronavirus Disease","authors":"Lamya Mallasi, Fatimah A. Alsaeed, Dina M. D. Badr, S. Salama","doi":"10.3889/oamjms.2023.11537","DOIUrl":"https://doi.org/10.3889/oamjms.2023.11537","url":null,"abstract":"Coronavirus disease is a serious viral infection that is characterized by severe inflammation and lymphopenia. The virus attacks many organs causing acute respiratory distress and malfunctioning of the organs leading to death. Through strengthening of the innate immune system, a balanced diet plays a critical role in defense against bacterial and viral diseases. A healthy diet before, during and after an infection can lessen the severity of the symptoms and speed up the recovery of damaged cells. Due to the Mediterranean diet’s high concentration of bioactive polyphenols, which have antioxidant, anti-inflammatory, and antithrombic properties, numerous studies have suggested that it is a preventative dietary strategy against many diseases including coronavirus disease. Nutrition and herbal plants play a key role to enhance the immunity of people to protect and fight against coronavirus. Diet rich in antioxidants and phytochemicals represents perfect barrier to the virus through elevation of the innate immunity of the body. In addition, gut microbiota including prebiotics, probiotics, and synbiotics were found to enhance immunity to reduce the symptoms of the disease during infection. Protein-rich foods and honey bee products reported significant role during and post-coronavirus infection. This review presents updated information from original pre-clinical and clinical researches, and review articles as well to expose the nutritive strategies including breastfeeding benefits to infants pre-infection, during, and post-infection with coronavirus.","PeriodicalId":19562,"journal":{"name":"Open Access Macedonian Journal of Medical Sciences","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49178917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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