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OTH-1 SARS-CoV-2 Infection in patients with autoimmune hepatitis 自身免疫性肝炎患者的OTH-1 SARS-CoV-2感染
Pub Date : 2021-11-01 DOI: 10.1136/gutjnl-2021-bsg.13
T. Marjot, G. Buescher, M. Sebode, Eleanor Barnes, A. Barritt, M. Armstrong, Luke Baldelli, J. Kennedy, C. Mercer, A. Ozga, C. Casar, C. Schramm, A. Moon, G. Webb, A. Lohse
OTH-1 Figure 1(A) AIH v non-AIH CLD (B) AIH v non-CLD[Figure omitted. See PDF]ConclusionDespite immunosuppressive treatment, AIH patients were not at increased risk of adverse outcomes from COVID-19 compared to other causes of CLD and to matched cases without liver disease.
图1(A) AIH vs non-AIH CLD (B) AIH vs non-CLD[图略。结论:尽管进行了免疫抑制治疗,与其他原因的CLD和无肝脏疾病的匹配病例相比,AIH患者的不良后果风险并未增加。
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引用次数: 0
OTH-7 Integrated care plans for alcohol-related high impact service users reduces hospital attendances and admissions OTH-7 .针对与酒精有关的高影响服务使用者的综合护理计划减少了住院率和入院率
Pub Date : 2021-11-01 DOI: 10.1136/gutjnl-2021-bsg.14
S. Masson, S. Forrest, L. Jopson
eight (83%) of AIH patients were taking one or more immunosuppressive drug. There were no differences in rates of major outcomes between AIH and non-AIH CLD including hospitalisation (76% vs 85%; p=0.06), ICU admission (29% vs. 23%; p=0.240), and death (23% vs. 20%; p=0.643). Fac-tors associated with death within the AIH cohort included age (OR 2.16/10 years; 1.07 – 3.81), Child-Turcotte-Pugh (CTP) class B (OR 42.48; 4.40 – 409.53), and CTP-C cirrhosis (OR 69.30; 2.83 – 1694.50), but not use of immunosuppression. Propensity score matched (PSM) analysis
8例(83%)AIH患者正在服用一种或多种免疫抑制药物。AIH和非AIH CLD的主要结局发生率无差异,包括住院(76% vs 85%;p=0.06), ICU住院率(29% vs. 23%;P =0.240)和死亡(23% vs. 20%;p = 0.643)。AIH队列中与死亡相关的因素包括年龄(OR 2.16/10年;1.07 - 3.81), child - turcote - pugh (CTP) B类(OR 42.48;4.40 - 409.53), CTP-C型肝硬化(OR 69.30;2.83 - 1694.50),但不使用免疫抑制。倾向评分匹配(PSM)分析
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引用次数: 0
OTH-10 Lipid monitoring and hyperlipidaemia in patients on home parenteral nutrition 家庭肠外营养患者的OTH-10血脂监测和高脂血症
Pub Date : 2021-11-01 DOI: 10.1136/gutjnl-2021-bsg.27
Thomas Rowland, S. Heasman, Emma Priestley, L. Gemmell, C. Mountford, N. Thompson
OFR-6 Table 1 Diagnostic Yield, n (%) of Pathogenic/Likely Pathogenic Variants in Polyposis and Colorectal Cancer Associated Genes in MCRA patients. Presented as overall diagnostic yield and diagnostic yield in each associated gene of interest stratified by adenoma burden Abstracts A16 Gut 2021;70(Suppl 4):A1–A220 on N ovem er 0, 2021 by gest. P rocted by coright. http/gut.bm jcom / G t: frst pulished as 10.113utjnl-2021-B S G 28 on 7 N ovem er 221. D ow nladed fom
表1 MCRA患者息肉病和结直肠癌相关基因致病性/可能致病性变异的诊断率n (%)按腺瘤负荷分层显示每个相关基因的总体诊断率和诊断率[摘要]A16 Gut 2021;70(补品4):A1-A220在N - ovem上,2021年。P由赖特保护。http /直觉。jj.com / gt:首次出版号10.113utjnl-2021- bsg28,出版日期:2011年7月7日。我们从
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引用次数: 0
The Utility and Feasibility of Routine Use of a Patient-Reported Outcome Measure in Paediatric Dentistry 儿科牙科常规使用患者报告结果测量的实用性和可行性
A. Graham, R. Knapp, H. Rodd, Z. Marshman, H. Zaitoun, F. Gilchrist
Within healthcare services, there is increasing emphasis to incorporate patient-reported outcome measures (PROMs), rather than relying solely on clinical outcomes. A 12-item caries-specific measure (CARIES-QC) has been developed and validated for children aged 5–16 years. To date, the routine use of PROMs in paediatric dentistry new patient clinics (NPC) has not been reported. The aim was to conduct a pilot study to assess the feasibility, utility and validity of routine use of a PROM in paediatric dentistry NPC in a UK teaching hospital. Children attending NPC over a four-week period were asked to complete CARIES-QC with an additional free-text box. Interviews were held with members of staff to assess the feasibility of using a PROM routinely. CARIES-QC was completed by 99 children. Almost half of the participants had caries (n = 49, 49.5%). CARIES-QC demonstrated good internal consistency (Cronbach’s alpha = 0.9) and reliability with the global question (r = 0.75, p = 0.01). Clinical staff valued the information provided by the PROM. An electronic delivery method would be beneficial to both clinical and administrative staff. CARIES-QC was able to capture impacts for children with a range of oral conditions. Its use aided treatment planning and future studies should investigate the use of an electronic delivery system to reduce the administrative burden.
在医疗保健服务中,越来越强调纳入患者报告的结果测量(PROMs),而不是仅仅依赖临床结果。针对5-16岁儿童制定并验证了12项龋齿专项测量(龋齿- qc)。迄今为止,在儿科牙科新患者诊所(NPC)常规使用PROMs尚未见报道。目的是进行一项试点研究,以评估在英国一家教学医院儿科牙科NPC中常规使用PROM的可行性、实用性和有效性。参加为期四周的NPC的儿童被要求完成CARIES-QC和一个额外的自由文本框。与工作人员进行了面谈,以评估例行使用PROM的可行性。99名儿童完成了CARIES-QC。几乎一半的参与者有龋齿(n = 49, 49.5%)。CARIES-QC具有良好的内部一致性(Cronbach’s alpha = 0.9)和整体问题的信度(r = 0.75, p = 0.01)。临床工作人员重视PROM提供的信息。电子传送方法将有利于临床和行政人员。龋齿质量控制能够捕捉到对患有一系列口腔疾病的儿童的影响。它的使用辅助治疗计划和未来的研究应调查使用电子传送系统,以减少行政负担。
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引用次数: 1
Stress Distribution in Modified Veneer Crowns: 3D Finite Element Analysis 改良牙冠的应力分布:三维有限元分析
C. Madruga, G. F. Ramos, A. Borges, G. Saavedra, R. Souza, R. Marinho, M. Penteado
(1) Background: to propose a new approach for crown veneers, with the use of an aesthetic porcelain coating, only in part of the zirconia infrastructure, and to analyze its biomechanical behavior to minimize chipping failures. (2) Methods: a maxillary molar was modeled using CAD software, preparing for traditional crowns and veneer crowns with various lengths. Five groups were formed: M—control group (monolithic crown of ultra-translucent zirconia); B—conventional (bilayer crown of ultra-translucent zirconia and ceramic covering); V—veneer (ultra-translucent zirconia crown with reduction only in the buccal and application of covering ceramics); V1—ultra-translucent zirconia crown with buccal reduction and 1 mm occlusal extension for covering ceramic application); V1.5—ultra-translucent zirconia crown with buccal reduction and 1.5 mm occlusal extension for application of covering ceramics. A load of 600 N was performed axially to a fossa bottom to simulate parafunction, and 300 N to the cusp tip to obtain the maximum principal stress results. (3) Results: group B showed a higher stress concentration in the occlusal region of the restorations, while the other groups absorbed the stress and dissipated it throughout the crown, presenting a higher stress concentration in the interface region with the tooth. (4) Conclusion: the highly translucent zirconia ceramic only associated with buccal covering ceramic could add aesthetic gain and rigidity to the system and could be a good option to restore maxillary molars in patients who do not have parafunction.
(1)背景:提出一种冠贴面的新方法,使用美观的瓷涂层,仅在部分氧化锆基础结构中使用,并分析其生物力学行为,以减少切屑失败。(2)方法:采用CAD软件对上颌磨牙进行建模,制备不同长度的传统冠和贴面冠。分为五组:m -对照组(超半透明氧化锆整体冠);b -常规(超透明氧化锆和陶瓷覆盖的双层冠);v -贴面(超半透明氧化锆冠,仅在颊部还原,并应用覆盖陶瓷);v1 -超半透明氧化锆冠,下颌复位,咬合延伸1mm,用于覆盖陶瓷应用);v1.5 -超半透明氧化锆冠,下颌复位,咬合延伸1.5 mm,用于覆盖陶瓷。对凹底施加600 N的轴向载荷以模拟副功能,对尖尖施加300 N的轴向载荷以获得最大主应力结果。(3)结果:B组修复体咬合区应力集中较高,而其他组在全冠上吸收并消散应力,与牙体界面区应力集中较高。(4)结论:高度半透明的氧化锆陶瓷仅与颊覆盖陶瓷联合使用,可增加系统的美观性和刚性,是无功能障碍患者上颌磨牙修复的良好选择。
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引用次数: 2
Association between Diabetes and Dental Caries in Spanish Adults: A Cross-Sectional Study Including 23,089 Adults 西班牙成年人糖尿病与龋齿之间的关系:一项包括23,089名成年人的横断面研究
L. Jacob, J. Shin, I. Grabovac, J. Haro, A. Koyanagi, M. Tully, M. Trott, Jong Yeob Kim, S. Pardhan, Lee Smith, G. F. López Sánchez
The aim of the study was to investigate the cross-sectional association between diabetes and dental caries in a representative sample of 23,089 adults residing in Spain. Data from the Spanish National Health Survey 2017 were analysed. Diabetes (independent variable) and dental caries (dependent variable) were evaluated through a self-reported questionnaire. The association between diabetes and dental caries in the overall sample was assessed using logistic regression models adjusted for sex, age, marital status, education, smoking, alcohol consumption, obesity, hypertension, and hypercholesterolemia. The prevalence of dental caries was 20.6% in the overall population and was significantly higher in men and in young (≤40 years) and middle-aged adults (41–65 years) than in women and older adults (>65 years), respectively. After adjusting for control variables, there was a positive and significant association between diabetes and dental caries in the overall population (OR = 1.30, 95% CI = 1.15–1.46). The relationship between diabetes and dental caries was particularly strong in women (OR = 1.45, 95% CI = 1.22–1.71) and in adults aged ≤40 years (OR = 1.80, 95% CI = 1.05–3.05). In conclusion, in this large representative sample of Spanish adults, diabetes was associated with having a higher prevalence of dental caries, with females and younger adults at greatest risk. Patients with diabetes and dental practitioners should be aware of these associations and act accordingly. Future research should aim to investigate the mediating factors involved in the observed association between diabetes and dental caries.
该研究的目的是调查糖尿病和龋齿之间的横断面关系,研究对象为23,089名居住在西班牙的成年人。分析了2017年西班牙国家健康调查的数据。糖尿病(自变量)和龋齿(因变量)通过自我报告问卷进行评估。在整个样本中,糖尿病和龋齿之间的关系通过调整性别、年龄、婚姻状况、教育程度、吸烟、饮酒、肥胖、高血压和高胆固醇血症等因素的logistic回归模型进行评估。总体人群龋齿患病率为20.6%,男性、青年(≤40岁)和中年人(41-65岁)的龋齿患病率分别高于女性和老年人(>65岁)。在调整控制变量后,总体人群中糖尿病和龋齿之间存在显著正相关(OR = 1.30, 95% CI = 1.15-1.46)。糖尿病与龋齿之间的关系在女性(OR = 1.45, 95% CI = 1.22-1.71)和≤40岁的成年人(OR = 1.80, 95% CI = 1.05-3.05)中尤为明显。总之,在这个西班牙成年人的大型代表性样本中,糖尿病与更高的龋齿患病率相关,女性和年轻人的风险最大。糖尿病患者和牙科医生应该意识到这些关联,并采取相应的行动。未来的研究应着眼于探讨糖尿病与龋病之间的关联的中介因素。
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引用次数: 0
Expansion of Preventive Dental Service Coverage for Certain Medicaid Beneficiaries in Texas: A Call for Dental Policy Effectiveness Action 扩大预防牙科服务覆盖某些医疗补助受益人在得克萨斯州:牙科政策有效性行动的呼吁
Naiya Patel, Neel Patel
Background: It is vital to provide evidence-based research documentation to guide policy decision-making. There is a limited number of studies that participate in dental policy evidence-based research. Case Description: Texas is one of the states with limited dental service coverage for its Medicaid Beneficiaries. The recent senate bill 87R 1152 proposes expansion of dental preventive service to disability status Medicaid Beneficiaries. It is vital to understand how effective the extensive dental service under Medicaid coverage is through evidence-based research. True causal analysis of such public policies by utilizing observational data is only feasible through limited identification strategies. The current paper identifies that. Practical Implication: Through the identified research plan and conceptual framework, it can be established if extensive Medicaid dental service coverages effectively prevent dental disease burden in Texas.
背景:提供基于证据的研究文件对指导政策决策至关重要。参与牙科政策循证研究的研究数量有限。案例描述:德克萨斯州是有限的牙科服务覆盖其医疗补助受益人的州之一。最近的参议院法案87R 1152提议将牙科预防服务扩大到残疾医疗补助受益人。通过基于证据的研究,了解医疗补助覆盖范围内广泛的牙科服务的有效性是至关重要的。只有通过有限的识别策略,才能利用观测数据对此类公共政策进行真正的因果分析。当前的论文确认了这一点。实践意义:通过确定的研究计划和概念框架,它可以建立如果广泛的医疗补助牙科服务覆盖有效地预防牙科疾病负担在得克萨斯州。
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引用次数: 0
BASILAR INVAGINATION: IMPORTANCE OF CRANIOMETRIC MEASUREMENT 颅底凹陷:颅测量的重要性
Pub Date : 2021-09-01 DOI: 10.1016/J.OOOO.2021.04.031
N. Manila, H. Liang, M. Nair, M. Tahmasbi
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引用次数: 0
MORPHOLOGIC VARIATIONS OF THE INFERIOR ALVEOLAR NERVE CANAL THROUGH THREE-DIMENSIONAL COMPUTED TOMOGRAPHY 三维计算机断层扫描下牙槽神经管的形态学变化
Pub Date : 2021-09-01 DOI: 10.1016/J.OOOO.2021.04.048
D. Alhazmi, T. Allareddy, S. Venugopalan
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引用次数: 0
PLEXIFORM SCHWANNOMA INVOLVING THE ANTERIOR MANDIBLE 累及前下颌的丛状神经鞘瘤
Pub Date : 2021-09-01 DOI: 10.1016/J.OOOO.2021.04.045
M. Shinde, Veeratrishul Allareddy, S. Anamali
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引用次数: 0
期刊
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
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