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Response by Author to Reader's Comment "Hand Functions Following Prone-weight Bearing on Upper Limb with Active Elbow Extension versus Modified Constraint-Induced Movement Therapy in Children with Unilateral Cerebral Palsy: A Randomized Clinical Trial" by Narayan et al. (2025). 作者对Narayan等人(2025)的读者评论“单侧脑瘫儿童上肢负重活动与改良约束诱导运动治疗的手部功能:一项随机临床试验”的回应。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-12 DOI: 10.1177/10538135251367202
Amitesh Narayan
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引用次数: 0
Comment on "Hand Functions Following Prone-weight Bearing on Upper Limb with Active Elbow Extension Versus Modified Constraint-Induced Movement Therapy in Children with Unilateral Cerebral Palsy: A Randomized Clinical Trial" by Narayan et al. (2025). 评论Narayan等人(2025)的“单侧脑瘫儿童主动肘部伸展后上肢倾向负重后的手功能与改良的约束诱导运动疗法:一项随机临床试验”。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-04 DOI: 10.1177/10538135251363326
Hafsa Tariq, Tayba Arab Farooqi
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引用次数: 0
Commentary on "Hand functions following prone-Weight bearing on upper limb with active elbow extension versus modified constraint induced Movement therapy in children with unilateral cerebral palsy - a randomised clinical trial". 对“单侧脑瘫儿童主动肘部伸展和改良约束诱导运动治疗上肢倾向负重后的手功能-一项随机临床试验”的评论。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-04 DOI: 10.1177/10538135251363329
Jyoti James, Antar Das, Sidharth Bansal
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引用次数: 0
A Quality Improvement Initiative to Optimize Early Mobilization in Acute Intracerebral Hemorrhage: A Pre-Post Intervention Study. 优化急性脑出血早期动员的质量改进倡议:干预前后研究。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-06-09 DOI: 10.1177/10538135251344930
Hsiao-Ching Yen, Yun-Chen Tsai, Guan-Shuo Pan

BackgroundPrimary intracerebral hemorrhage (ICH) carries high mortality and disability risks. Although early mobilization is beneficial, concerns about physiological instability often delay mobilization.ObjectiveTo evaluate whether a structured early mobilization protocol improves functional mobility and reduces adverse events in critically ill ICH patients.MethodThis retrospective pre-post study included 192 patients with ICH (ICH score 0-4) admitted to a dedicated stroke center. In the pre-implementation phase in 2022, patients received standard care. In the post-implementation phase in 2023, a standardized mobility protocol, incorporating time-based stratification, neurological thresholds, and safety criteria to guide activity progression, was introduced. Primary outcomes included the Modified ICU Mobility Scale (MIMS) score at intensive care unit (ICU) discharge and the occurrence of adverse events.ResultsThe post-implementation group (99 patients) showed higher MIMS scores at ICU discharge, with a greater proportion achieving out-of-bed sitting during their ICU stay compared to the pre-implementation group (93 patients). Non-serious adverse events in the former decreased significantly; ICU and hospital lengths of stay were shorter but not statistically significant.ConclusionThe structured pathway enabled safer, earlier mobilization and improved ICU functional outcomes. While mobility benefits were observed, caution is warranted in interpreting non-significant trends in length of stay.

背景原发性脑出血(ICH)具有高死亡率和致残风险。虽然早期活动是有益的,但对生理不稳定的担忧往往会推迟活动。目的评价结构化的早期活动方案是否能改善脑出血危重症患者的功能活动能力并减少不良事件。方法回顾性研究纳入192例脑出血患者(脑出血评分0-4分)。在2022年实施前阶段,患者接受了标准护理。在2023年的实施后阶段,引入了标准化的活动方案,包括基于时间的分层、神经阈值和安全标准,以指导活动进展。主要结局包括重症监护病房(ICU)出院时修改的ICU活动能力量表(MIMS)评分和不良事件的发生。结果与实施前组(93例)相比,实施后组(99例)在ICU出院时的MIMS评分更高,在ICU住院期间实现床下坐的比例更高。前者的非严重不良事件显著减少;ICU和住院时间较短,但无统计学意义。结论:结构化通路可使活动更安全、更早,并改善ICU功能预后。虽然观察到移动性的好处,但在解释住院时间的非显著趋势时,需要谨慎。
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引用次数: 0
Analysis of Warm Acupuncture Combined with Rehabilitation Training for Lower Limb Motor Dysfunction in Cerebral Infarction Patients. 温针结合康复训练治疗脑梗死患者下肢运动功能障碍的疗效分析。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-14 DOI: 10.1177/10538135251339348
Man Li, Nan Su

ObjectiveTo evaluate the efficacy of warm acupuncture combined with rehabilitation training on lower-limb motor dysfunction in cerebral infarction (CI) patients.MethodsSixty CI patients with lower-limb motor dysfunction (Feb 2019 to Apr 2021) were enrolled. The control group received rehabilitation training, while the study group received warm acupuncture plus rehabilitation. The outcomes, including Functional Independence Measure (FIM), 10-meter maximum walking speed (MWS), Berg-balance scale (BBS), Barthel index, and Holden walking ability rating scale, were compared.ResultsThe study group showed significantly better results than the control group. After treatment, the study group's FIM and BBS scores were higher at 1-, 4-, and 6-week follow-ups. MWS scores of the study group improved significantly, while the control group showed less improvement. The Holden walking ability rating scale was also more favorable for the study group.ConclusionWarm acupuncture combined with rehabilitation training significantly improves lower-limb motor dysfunction in CI patients, demonstrating superior outcomes compared to rehabilitation alone.

目的评价温针结合康复训练治疗脑梗死患者下肢运动功能障碍的疗效。方法入选2019年2月至2021年4月60例下肢运动功能障碍CI患者。对照组采用康复训练,研究组采用温针加康复治疗。比较功能独立性量表(FIM)、10米最大步行速度量表(MWS)、Berg-balance量表(BBS)、Barthel指数(Barthel index)和Holden步行能力评定量表(Holden walking ability rating scale)。结果研究组的治疗效果明显优于对照组。治疗后,研究组的FIM和BBS评分在1周、4周和6周随访时均较高。研究组的MWS评分有明显改善,而对照组改善较少。霍尔顿行走能力评定量表对研究组也更有利。结论温针联合康复训练可显著改善CI患者下肢运动功能障碍,效果优于单纯康复。
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引用次数: 0
Identifying Fall Risk within 6 Months Post-Discharge Through Balance Tasks Analysis in Inpatients with Subacute Stroke: Prospective Cohort Study. 通过平衡任务分析确定亚急性卒中住院患者出院后6个月内的跌倒风险:前瞻性队列研究
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-07-08 DOI: 10.1177/10538135251356173
Tatsuya Igarashi, Yuta Tani, Hironobu Kakima, Shota Hayashi

BackgroundBalance impairments, stemming from disruptions in motor, and cognitive systems, are key contributors to fall risk.ObjectiveThis study aimed to identify balance tasks associated with fall risk within 6 months of discharge in inpatients with subacute stroke.MethodsThis prospective cohort study included patients with subacute stroke who completed the Mini-Balance Evaluation Systems Test (Mini-BESTest), Fugl-Meyer Assessment for the Lower Extremities, and Mini-Mental State Examination before discharge. Falls were self-reported via telephone survey six months post-discharge. Logistic regression was used to identify significant predictors, with sensitivity analyses to evaluate robustness.ResultsAmong 50 patients, 30% experienced falls within six months. Regression analysis identified stand on one leg (OR = 4.70, 95% CI 1.31-16.85, p = 0.018), compensatory stepping correction of backward (OR = 3.48, 95% CI 1.36-8.92, p = 0.009) and lateral (OR = 3.00, 95% CI 1.02-8.84, p = 0.046) as significant balance tasks associated with fall risk. Forward compensatory stepping corrections were associated with increasing age, whereas standing with eyes closed and walking with head turned horizontally were associated with fall risk in interaction with motor paresis and cognitive integration.ConclusionsOne leg standing and compensatory stepping correction of backward and lateral were significant balance tasks related to fall risk.

运动和认知系统紊乱导致的平衡障碍是导致跌倒风险的关键因素。目的:本研究旨在确定亚急性脑卒中住院患者出院后6个月内与跌倒风险相关的平衡任务。方法本前瞻性队列研究纳入亚急性脑卒中患者,这些患者在出院前完成了迷你平衡评估系统测试(Mini-BESTest)、下肢Fugl-Meyer评估和迷你精神状态检查。出院后6个月通过电话调查自我报告跌倒情况。采用Logistic回归识别显著的预测因子,并用敏感性分析评估稳健性。结果50例患者中有30%在6个月内跌倒。回归分析发现单腿站立(OR = 4.70, 95% CI 1.31-16.85, p = 0.018)、补偿性后退步矫正(OR = 3.48, 95% CI 1.36-8.92, p = 0.009)和侧步矫正(OR = 3.00, 95% CI 1.02-8.84, p = 0.046)是与跌倒风险相关的重要平衡任务。向前补偿性步进矫正与年龄增长有关,而闭眼站立和水平转动头部行走与运动性神经麻痹和认知整合相互作用与跌倒风险相关。结论单腿站立和后侧补偿性步进矫正是与跌倒风险相关的重要平衡任务。
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引用次数: 0
Are Virtual Reality Interventions Effective in Improving Outcomes in People with Multiple Sclerosis? A Cochrane Review Summary with Commentary. 虚拟现实干预能有效改善多发性硬化症患者的预后吗?Cochrane综述综述及评论。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-09-04 DOI: 10.1177/10538135251372057
Bhasker Amatya, Fary Khan

BackgroundA wide range of virtual reality (VR) applications are currently used in rehabilitation to support people with multiple sclerosis (pwMS) in improving limb function, balance, postural control, gait training, and cognitive abilities. Despite its widespread use, there is a lack of systematic evaluation for the effectiveness of VR in the rehabilitation.ObjectiveCommentary on the systematic review by De Keersmaecker et al. (2025) which assessed the effects of VR interventions on lower limb and gait function, and balance and postural control in pwMS.MethodsThis review conducted a comprehensive search of the health science databases for (quasi-) randomized controlled trials (RCTs) that assessed virtual reality (VR) interventions in adult pwMS.ResultsThe review included 33 RCTs with a total of 1,294 participants. VR interventions varied across studies, including immersive and non-immersive approaches targeting motor and cognitive rehabilitation. Compared to no intervention, VR demonstrated a moderate positive effect on upper limb function and quality of life, suggesting that it could be a viable rehabilitation tool for improving motor performance and patient well-being. Compared with conventional therapy, VR interventions were more effective in improving balance and postural control. However, for other rehabilitation outcomes, such as gait function, cognitive function, and fatigue management, VR did not show significant differences compared to conventional therapy.ConclusionsVR can be a useful adjunct to traditional rehabilitation, but it may not be superior in all aspects of MS rehabilitation, unambiguous evidence regarding the effect of virtual reality training in multiple sclerosis is still missing. The authors emphasized the need for further research, particularly high-quality, large-scale RCTs, to strengthen the evidence base for VR in MS rehabilitation.

目前,广泛的虚拟现实(VR)应用于康复,以支持多发性硬化症(pwMS)患者改善肢体功能,平衡,姿势控制,步态训练和认知能力。尽管VR的应用非常广泛,但目前还缺乏对其康复效果的系统评价。目的对De Keersmaecker等人(2025)的系统综述进行评论,该综述评估了VR干预对pwMS患者下肢和步态功能以及平衡和姿势控制的影响。方法:本综述对健康科学数据库中评估虚拟现实(VR)干预成人pwMS的(准)随机对照试验(rct)进行了全面检索。结果纳入33项随机对照试验,共1294名受试者。VR干预在不同的研究中有所不同,包括针对运动和认知康复的沉浸式和非沉浸式方法。与不进行干预相比,VR对上肢功能和生活质量有中度的积极影响,这表明它可能是一种可行的康复工具,可以改善运动表现和患者的幸福感。与常规治疗相比,VR干预在改善平衡和姿势控制方面更有效。然而,对于其他康复结果,如步态功能、认知功能和疲劳管理,VR与常规治疗相比没有显着差异。结论虚拟现实训练可以作为传统康复的辅助手段,但并非在MS康复的各个方面都有优势,虚拟现实训练在多发性硬化症康复中的效果尚缺乏明确的证据。作者强调需要进一步的研究,特别是高质量、大规模的随机对照试验,以加强VR在MS康复中的证据基础。
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引用次数: 0
Validation of the Arabic Version of Multiple Sclerosis Quality of Life-29 (MSCOL-29-Ar): Cross-cultural Adaptation and Psychometric Analysis. 阿拉伯版多发性硬化症生活质量量表29 (MSCOL-29-Ar)的验证:跨文化适应和心理测量分析。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-27 DOI: 10.1177/10538135251344929
Afaf Am Shaheen As, Jude A Alsharafi, Mishel M Aldaihan, Asma S Alrushud, Asma A Aldera, Mai A Alder, Saad Alhammad, Ahmed Farrag, Walaa Elsayed, Muneera Almurdi, Maha Algabbani

Background and objectivesTo translate and adapt the Multiple Sclerosis Quality of Life-29 into Arabic (MSQOL-29-Ar) and assess its psychometric properties in people with multiple sclerosis (MS).MethodsGenerally, 101 Arabic-speaking adults with MS aged 21 to 60 were recruited. Construct validity was tested by correlating MSQOL-29-Ar with the Arabic Functional Assessment of Multiple Sclerosis (FAMS-AR) and Multiple Sclerosis International Quality of Life (MusiQOL). Known-group validity was assessed by correlating the scale's Physical Health Composite (PHC) and Mental Health Composite (MHC) scores with the demographic and clinical data. Test-retest reliability, internal consistency, standard error of measurement (SEM), minimal detectable change (MDC95), limit of agreement (LOA), responsiveness, and floor/ceiling effects were also investigated.ResultsPHC and MHC scores correlated strongly with FAMS-ARA (r = 0.76 and 0.70, respectively).PHC scores were associated with age, employment, and MS chronicity, while MHC scores correlated with the Expanded Disability Status Scale. Internal consistency was acceptable (PHC α = 0.80; MHC α = 0.90), with excellent test-retest reliability (PHC r = 0.76; MHC r = 0.90). SEM (1.4-1.6) and MDC95 (4.3-3) were low. Responsiveness analysis indicated moderate accuracy (AUC = 0.70-0.75) with on-floor/ceiling effects.ConclusionMSQOL-29-Ar is valid and reliable for assessing HQOL in people with MS, making it suitable for clinical and rehabilitation settings.

背景与目的将多发性硬化症生活质量量表(MSQOL-29-Ar)翻译成阿拉伯文,并评估其在多发性硬化症(MS)患者中的心理测量特性。方法一般招募101例21 ~ 60岁阿拉伯语多发性硬化症患者。通过将MSQOL-29-Ar与阿拉伯语多发性硬化症功能评估(FAMS-AR)和多发性硬化症国际生活质量(musiol)相关联来检验结构效度。已知组效度是通过将量表的生理健康综合(PHC)和心理健康综合(MHC)得分与人口学和临床数据相关联来评估的。测试-重测信度、内部一致性、测量标准误差(SEM)、最小可检测变化(MDC95)、一致性限(LOA)、响应性和下限/上限效应也进行了调查。结果sphc和MHC评分与FAMS-ARA相关性较强(r分别为0.76和0.70)。PHC评分与年龄、就业和MS慢性程度相关,而MHC评分与扩展残疾状态量表相关。内部一致性可接受(PHC α = 0.80;MHC α = 0.90),重测信度极好(PHC r = 0.76;MHC r = 0.90)。SEM(1.4-1.6)和MDC95(4.3-3)较低。响应性分析显示准确度中等(AUC = 0.70-0.75),具有地板/天花板效应。结论msqol -29- ar评价MS患者HQOL有效、可靠,适用于临床和康复治疗。
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引用次数: 0
From Concept to Practice: Integrating Contextual Factors into Neurorehabilitation Among Physical Therapists. 从概念到实践:将环境因素融入物理治疗师的神经康复。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-05-28 DOI: 10.1177/10538135251344927
Maha Almarwani, Emtenan Alsadhan

BackgroundNeurological disorders are the leading cause of global disability. To enhance neurorehabilitation effectiveness, it is essential to consider contextual factors that influence patient outcomes and the overall experience.ObjectiveThis study aimed to examine the integration of contextual factors into neurorehabilitation practice among physical therapists, focusing on their frequency of use, associated beliefs, ethical considerations, and communication strategies.MethodsA cross-sectional web-based survey was disseminated to a convenience sample of physical therapy professionals via various online platforms. The survey collected demographic data and information regarding the integration of contextual factors into neurorehabilitation practice.ResultsA total of 369 physical therapists completed the survey. Respondents reported moderate use of contextual factors (43%), with verbal communication (85%), positive attitude (82%), and physical contact (75%) the most frequently employed factors. The strongest beliefs about the influence of contextual factors on therapeutic outcomes were linked to verbal communication and optimistic behavior. No significant correlations were found between respondents' characteristics and the use of contextual factors.ConclusionPhysical therapists recognize the importance of contextual factors such as verbal communication, positive attitudes, and a professional approach in neurorehabilitation. Enhanced training is recommended to further integrate these factors into neurorehabilitation practice and optimize patient outcomes.

背景:神经系统疾病是全球致残的主要原因。为了提高神经康复的有效性,必须考虑影响患者预后和整体体验的环境因素。目的本研究旨在探讨环境因素在物理治疗师神经康复实践中的整合,重点关注其使用频率、相关信念、伦理考虑和沟通策略。方法通过各种网络平台向方便的物理治疗专业人员分发一份基于网络的横断面调查。该调查收集了人口统计数据和有关将环境因素整合到神经康复实践中的信息。结果共有369名物理治疗师完成调查。受访者表示适度使用情境因素(43%),其中最常使用的因素是语言交流(85%)、积极态度(82%)和身体接触(75%)。关于情境因素对治疗结果影响的最强烈信念与语言交流和乐观行为有关。被调查者的特征与语境因素的使用之间没有显著的相关性。结论物理治疗师认识到语言沟通、积极态度和专业方法等环境因素在神经康复中的重要性。建议加强训练,进一步将这些因素整合到神经康复实践中,并优化患者的预后。
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引用次数: 0
Effectivity of neuromuscular electrical stimulation and oral sensorimotor stimulation as therapeutic interventions for pediatric dysphagia: A comparative study of swallowing outcomes. 神经肌肉电刺激和口腔感觉运动刺激作为儿童吞咽困难的治疗干预措施的有效性:吞咽结果的比较研究。
IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2025-09-01 Epub Date: 2025-06-17 DOI: 10.1177/10538135251336048
Rizky Kusuma Wardhani, Luh Karunia Wahyuni, Budiati Laksmitasari, Mohamad Yanuar Amal, Chika Carnation Tandri, You Gyoung Yi

BackgroundPediatric dysphagia poses risks to feeding safety, nutrition, and overall health, especially in those with developmental or neurological disorders. While various treatments exist, including therapeutic, medical, and surgical options, oral sensorimotor stimulation (OSMS) and neuromuscular electrical stimulation (NMES) are commonly used non-invasive interventions. However, their relative effectiveness remains uncertain, with limited evidence on their advantages in managing specific types of dysphagia.ObjectiveThis prospective cohort study aimed to compare the effectiveness of NMES and OSMS in managing pediatric dysphagia.MethodsThis study recruited pediatric dysphagia patients for a two-month rehabilitation program, with either NMES or OSMS with pre- and post-intervention evaluations using video-fluoroscopic swallow studies, Modified Barium Swallow Impairment Profile (MBSImP) scores, and the 8-point Penetration-Aspiration Scale (PAS).ResultsA total of 26 children participated in the study. NMES significantly reduced MBSImP scores in both oral and pharyngeal impairments, and PAS. OSMS showed significant improvement in MBSImP scores, particularly in oral impairment.ConclusionsThe study suggests NMES benefits oropharyngeal dysphagia and reduces penetration and aspiration, while OSMS is effective for improving oral dysphagia.

儿童吞咽困难对喂养安全、营养和整体健康构成风险,特别是对那些患有发育或神经障碍的儿童。虽然存在各种治疗方法,包括治疗,医学和手术选择,但口腔感觉运动刺激(OSMS)和神经肌肉电刺激(NMES)是常用的非侵入性干预措施。然而,它们的相对有效性仍然不确定,关于它们在治疗特定类型吞咽困难方面的优势的证据有限。目的:本前瞻性队列研究旨在比较NMES和OSMS治疗小儿吞咽困难的有效性。方法:本研究招募儿童吞咽困难患者进行为期两个月的康复计划,采用NMES或OSMS进行干预前和干预后评估,使用视频透视吞咽研究、改良钡吞咽损伤评分(MBSImP)和8点渗透-吸入量表(PAS)。结果共26名儿童参与研究。NMES显著降低了口腔和咽损伤以及PAS的MBSImP评分。OSMS显示MBSImP评分有显著改善,尤其是在口腔损伤方面。结论NMES有利于口咽部吞咽困难,减少渗透和误吸,而OSMS对改善口咽部吞咽困难有效。
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引用次数: 0
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NeuroRehabilitation
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