Pub Date : 2023-01-01DOI: 10.29261/10.29261/pakvetj/2023.071
{"title":"Molecular Characterization of Cryptosporidium Infection and Analysis of Hematological and Biochemical Changes in Diarrheic Pre-weaned Calves in Egypt","authors":"","doi":"10.29261/10.29261/pakvetj/2023.071","DOIUrl":"https://doi.org/10.29261/10.29261/pakvetj/2023.071","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135057428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.028
Schizont-infected nucleated cells and anemia-induced hypoxia may cause acute kidney injury (AKI) in cattle with tropical theileriosis. In most cases, serum creatinine (sCr) fails to detect early kidney injury. Recently, urine biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL), Cystatin C (CysC), and Clusterin (Clu) have outperformed sCr in identifying AKI in various animal species. However, these markers have not been tested in cattle for AKI detection. This study investigated AKI in cattle with tropical theileriosis using serum and urinary NGAL, CysC, and Clu and compared them to standard renal function markers such as sCr, urine protein to creatinine (uPC) ratio and urine-specific gravity (USG). Seventeen cattle were infected with Theileria annulata (Th) and ten were controls (CTRL) in this investigation. The urinary NGAL (uNGAL) in the Th group was considerably (P<0.001) greater than that in the CTRL group. uCysC increased significantly in the Th group compared to CTRL group (P<0.001). The Th group had higher sClu than the CTRL group (P<0.001). There was a significant difference (p=0.005) in sCr concentrations between Th and CTRL groups, but the values were within the reference range in both groups. Th group had a higher uPC ratio than CTRL (p= 0.002), whereas USG was lower in Th group than in CTRL group (P<0.001). These results suggested that cattle with tropical Theileriosis have acute tubular injury.
{"title":"Urinary Neutrophil Gelatinase-Associated Lipocalin, Cystatin C and Clusterin as Biomarkers for Acute Kidney Injury in Cattle with Tropical Theileriosis","authors":"","doi":"10.29261/pakvetj/2023.028","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.028","url":null,"abstract":"Schizont-infected nucleated cells and anemia-induced hypoxia may cause acute kidney injury (AKI) in cattle with tropical theileriosis. In most cases, serum creatinine (sCr) fails to detect early kidney injury. Recently, urine biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL), Cystatin C (CysC), and Clusterin (Clu) have outperformed sCr in identifying AKI in various animal species. However, these markers have not been tested in cattle for AKI detection. This study investigated AKI in cattle with tropical theileriosis using serum and urinary NGAL, CysC, and Clu and compared them to standard renal function markers such as sCr, urine protein to creatinine (uPC) ratio and urine-specific gravity (USG). Seventeen cattle were infected with Theileria annulata (Th) and ten were controls (CTRL) in this investigation. The urinary NGAL (uNGAL) in the Th group was considerably (P<0.001) greater than that in the CTRL group. uCysC increased significantly in the Th group compared to CTRL group (P<0.001). The Th group had higher sClu than the CTRL group (P<0.001). There was a significant difference (p=0.005) in sCr concentrations between Th and CTRL groups, but the values were within the reference range in both groups. Th group had a higher uPC ratio than CTRL (p= 0.002), whereas USG was lower in Th group than in CTRL group (P<0.001). These results suggested that cattle with tropical Theileriosis have acute tubular injury.","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135057822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.093
{"title":"The Tumor Architecture and Mitotic Index of Canine Cutaneous Mast Cell Tumors as a Prognostic Indicator","authors":"","doi":"10.29261/pakvetj/2023.093","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.093","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135953731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.068
{"title":"Neuraminidase Inhibitors Resistance: The Irrational Use of Oseltamivir Can Lead to Genesis of Mutant Avian Influenza Viruses in The Field","authors":"","doi":"10.29261/pakvetj/2023.068","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.068","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69870212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.098
{"title":"Improved Gut Microbiota Escalates Muscle Function Rehabilitation and Ameliorates Oxidative Stress Following Mechanically Induced Peripheral Nerve Injury in Mice","authors":"","doi":"10.29261/pakvetj/2023.098","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.098","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135105625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.085
{"title":"The Effect of the Combination of Peste Des Petits Ruminants (PPR) Vaccine with Different Doses of Lentinan on Cytokines and Antibody Levels of Sheep","authors":"","doi":"10.29261/pakvetj/2023.085","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.085","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135500990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29261/pakvetj/2023.097
{"title":"Study on the Relationship between TGF-β1, MMP-9 and Diabetic Retinopathy in Diabetic Rat Model","authors":"","doi":"10.29261/pakvetj/2023.097","DOIUrl":"https://doi.org/10.29261/pakvetj/2023.097","url":null,"abstract":"","PeriodicalId":19845,"journal":{"name":"Pakistan Veterinary Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136367520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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