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Targeted Muscle Reinnervation and Regenerative Peripheral Nerve Interfaces Versus Standard Management in the Treatment of Limb Amputation: A Systematic Review and Meta-Analysis. 靶向肌肉神经移植和再生周围神经界面与标准管理在截肢治疗中的对比:系统回顾和荟萃分析
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-06-16 DOI: 10.1177/22925503221107462
Morgan Yuan, Matteo Gallo, Lucas Gallo, Minh Hq Huynh, Mark McRae, Matthew C McRae, Achilleas Thoma, Christopher J Coroneos, Sophocles H Voineskos

Introduction: Painful neuromas are a common postoperative complication of limb amputation often treated with secondary reinnervation. Surgical reinnervation include Targeted Muscle Reinnervation (TMR) and Regenerative Peripheral Nerve Interface (RPNI), and can be primary and secondary. The aim of this review is to assess the effects of primary TMR/RPNI at the time of limb amputation on the incidence and intensity of post-operative neuroma and pain. Methods: This review was registered a priori on PROSPERO (CRD42021264360). A search of the following databases was performed in June 2021: Medline, EMBASE, and CENTRAL. Unpublished trials were searched using clinicaltrials.gov. All randomized and non-randomized studies assessing amputation with a reinnervation strategy (TMR, RPNI) were included. Outcomes evaluated included the incidences of painful neuroma, phantom limb pain (PLP), residual limb pain (RLP), as well as severity of pain, and Pain intensity, behavior, and interference (PROMIS). Results: Eleven studies were included in this systematic review, and five observational studies for quantitative synthesis. Observational study evidence suggests that TMR/RPNI results in a statistically significant reduction in incidence, pain scores and PROMIS scores of PLP and RLP. Decreased incidence of neuromas favored primary TMR/RPNI, but this did not achieve statistical significance (p = 0.07). Included studies had moderate to critical risk of bias. Conclusion: The observational data suggests that primary TMR/RPNI reduces incidence, pain scores and PROMIS scores of PLP and RLP. Going forward, randomized trials are warranted to evaluate this research question, particularly to improve the certainty of evidence.

引言:疼痛性神经瘤是截肢术后常见的并发症,通常采用二次神经再支配治疗。手术再支配包括靶向肌肉再支配(TMR)和再生周围神经接口(RPNI),可以是原发性和继发性的。本综述的目的是评估截肢时原发性TMR/RPNI对术后神经瘤和疼痛的发生率和强度的影响。方法:本综述在PROSPERO(CRD42021264360)上预先登记。2021年6月对以下数据库进行了搜索:Medline、EMBASE和CENTRAL。使用clinicaltrials.gov搜索未发表的试验。包括所有用神经再支配策略(TMR,RPNI)评估截肢的随机和非随机研究。评估的结果包括疼痛神经瘤、幻肢疼痛(PLP)、残肢疼痛(RLP)的发生率,以及疼痛的严重程度,以及疼痛强度、行为和干扰(PROMIS)。结果:11项研究被纳入本系统综述,5项观察性研究被纳入定量综合。观察研究证据表明,TMR/RPNI可显著降低PLP和RLP的发病率、疼痛评分和PROMIS评分。神经瘤发生率的降低有利于原发性TMR/RPNI,但这并没有达到统计学意义(p = 0.07)。纳入的研究具有中度至临界的偏倚风险。结论:观察数据表明,原发性TMR/RPNI可降低PLP和RLP的发病率、疼痛评分和PROMIS评分。今后,有必要进行随机试验来评估这一研究问题,特别是提高证据的确定性。
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引用次数: 0
Resident Exposure and Involvement in Core Procedural Competencies within Pediatric Plastic Surgery. 住院医师接触和参与儿科整形外科核心程序能力
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-06-27 DOI: 10.1177/22925503221109072
Josephine A D'Abbondanza, Jessica G Shih, Aaron D C Knox, Nick Zhygan, Mitchell H Brown, Joel S Fish, Douglas J Courtemanche

Introduction: The implementation of competency-based residency training in plastic surgery is underway. Key competencies in plastic surgery have been previously identified, however, within the domain of pediatrics, data suggest limited exposure throughout training for Canadian graduates. This study aims to identify the exposure and involvement of residents in core pediatric cases. Methods: We performed a retrospective, multicenter review of plastic surgery resident case logs (T-Res, POWER, New Innovations) across 10 Canadian, English-speaking training programs between 2004 and 2014. Case logs were coded according to the 8 core pediatric competencies previously identified by a modified Delphi technique. Results: A total of 3061 of 59 405 cases (5.2%) logged by 55 graduating residents were core pediatric procedures with an average of 55.6 ± 23.0 cases logged per resident. The top 3 most commonly logged procedures were cleft lip repair, cleft palate repair, and setback otoplasty. The number of cases per program varied widely with the most at 731 and least at 85 logged cases. Roles across procedures have wide variation and residents are most commonly identified as the assistant rather than surgeon or co-surgeon. Conclusion: These findings highlight variability both within and across residency programs with a paucity of exposure and involvement in pediatric plastic surgery cases. This may present a conflict between current recommendations for residency-specific procedural competencies and true clinical exposure. Further curriculum development and simulation may be of benefit.

导言:在整形外科中实施基于能力的住院医师培训正在进行中。然而,在儿科领域,数据表明,在加拿大毕业生的整个培训过程中,整形外科的关键能力受到了限制。本研究旨在确定住院医师在核心儿科病例中的暴露和参与情况。方法:我们对2004年至2014年间10个加拿大英语培训项目的整形外科住院医师病例日志(T-Res, POWER, New Innovations)进行了回顾性的多中心回顾。病例记录根据先前通过改进的德尔菲技术确定的8项儿科核心能力进行编码。结果:55名毕业住院医师记录的59 405例病例中,共有3061例(5.2%)是核心儿科手术,平均每位住院医师记录的病例为55.6±23.0例。最常记录的前3名手术是唇裂修复、腭裂修复和耳廓成形术。每个项目的案例数量差异很大,最多的是731个,最少的是85个。手术过程中的角色有很大的差异,住院医生通常被认为是助理医生,而不是外科医生或联合外科医生。结论:这些发现突出了住院医师项目内部和跨住院医师项目的可变性,因为缺乏儿科整形手术病例的接触和参与。这可能会导致当前关于住院医师特定程序能力的建议与真实临床暴露之间的冲突。进一步的课程开发和模拟可能是有益的。
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引用次数: 0
Postoperative Prophylactic Antibiotic Use in Breast Reduction Mammoplasty: A Single Centre Retrospective Cohort Study. 乳房缩小术后预防性抗生素应用的单中心回顾性队列研究
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-06-15 DOI: 10.1177/22925503221107220
Véronique M Doucet, Jakob J Weirathmueller, Graham J McLeod, Kenneth A Murray

Introduction: Breast reduction mammoplasty (BRM) is a common procedure performed by plastic surgeons treating patients with hypermastia. It is customary to give preoperative prophylactic intravenous antibiotics for BRM, followed by several days of postoperative prophylactic oral antibiotics, despite the lack of evidence of their effectiveness in preventing surgical site infections (SSIs). The purpose of this study is to determine if the addition of prophylactic postoperative antibiotics is more effective in preventing SSIs in comparison to a single dose of preoperative prophylactic antibiotics in BRM. Methods: A retrospective analysis of 124 elective BRM cases by a single senior plastic surgeon was completed. Two study groups were formed based on the location of surgery and each group was assigned a different antibiotic regimen. The first antibiotic regimen consisted of a single preoperative intravenous dose of antibiotics (group 1), while the second regimen consisted of a preoperative intravenous dose followed by a 5-day course of oral antibiotics (group 2). Results: Overall SSI rate was 5.6%. Infection rate in group 1 was 8.1% in comparison to 3.2% for group 2 (P value .44). Overall, the incidence of complications was 29.0%; 38.7% in group 1 and 19.4% in group 2 (P value .03). Complications consisted of 35 cases of delayed wound healing, 7 SSIs and 2 hematomas requiring evacuation. Conclusion: Study results demonstrated that the use of postoperative prophylactic antibiotics for BRM had no significant effect on the rate of SSIs.

简介:乳房缩小乳房成形术(BRM)是整形外科医生治疗乳房肥大患者的常见手术。尽管缺乏证据表明其在预防手术部位感染(SSIs)方面的有效性,但通常在术前预防性静脉注射BRM抗生素,然后在术后几天预防性口服抗生素。本研究的目的是确定在BRM中,与单剂量术前预防性抗生素相比,添加预防性术后抗生素是否更有效地预防SSI。方法:对一位资深整形外科医生的124例择期BRM病例进行回顾性分析。根据手术地点组成两个研究组,每组被分配不同的抗生素方案。第一种抗生素方案包括术前单次静脉注射抗生素(第1组),而第二种方案包括术后静脉注射抗生素,然后口服抗生素5天(第2组)。结果:总的SSI发生率为5.6%。第1组的感染率为8.1%,而第2组为3.2%(P值.44)。总的来说,并发症的发生率为29.0%;第1组为38.7%,第2组为19.4%(P值.03)。并发症包括35例伤口愈合延迟,7例SSI和2例需要清除的血肿。结论:研究结果表明,BRM术后预防性抗生素的使用对SSIs的发生率没有显著影响。
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引用次数: 0
Reconstruction Using Perforator Propeller Flaps After Malignant Melanoma Resection of the Lower Extremity. 下肢恶性黑色素瘤切除术后穿支螺旋桨皮瓣重建
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-08-01 DOI: 10.1177/22925503221116279
Adela Alvarez Rio, Josep Oriol Roca Mas, Gonzalo Joaquin Soroa Moreno, Daniel Navarro Sanchez, Ivan Monge Castresana, Jaime Estrada Cuxart

Introduction: Surgical excision with margin of 2 cm is the treatment of choice in malignant cutaneous melanoma when Breslow index is >1 mm. When located on the lower limb, these resections can lead to large defects that require complex reconstruction in order to salvage the limb. The use of propeller-perforator flaps has multiple advantages such as the preservation of adjacent muscles, decrease in morbidity in the donor site, and good aesthetic and functional results. Our objective is to expose our experience and results with the use of propeller-perforator flaps for coverage of this kind of defects. Materials and Methods: Patients with malignant cutaneous melanoma of the lower limb who required reconstruction with a propeller-perforator flap between the years 2015 and 2021 in our plastic surgery department were included in this retrospective research. Demographic, reconstructive, oncologic, and functional data were collected and analyzed. Results: The cohort of 22 patients showed 100% of successful reconstructive outcomes. Only 2 patients experienced distal necrosis of the flap that was resolved with local dressings. Fast recovery and early capacity to walk were achieved in the majority of the patients with an average of 10.1 days until weight-baring walking. The 2-year overall and progression-free survival rates were 86.37% and 81.82%, respectively. Conclusion: The use of propeller perforator flaps for oncological defects coverage in the lower limb location has to be considered as a reliable choice as it takes less surgical time and a faster recovery. It allows limb salvage with an adequate length and functionality, with minimal donor site morbidity and a lower index of complications, contributing to improve patient's quality of life and not delaying other oncological treatments.

简介:当Breslow指数为bb10 - 1mm时,手术切除边缘2cm是恶性皮肤黑色素瘤的治疗选择。当位于下肢时,这些切除可能导致大的缺陷,需要复杂的重建才能挽救肢体。螺旋桨穿支皮瓣的使用具有多种优点,如保存邻近肌肉,减少供区发病率,良好的美观和功能效果。我们的目的是揭露我们的经验和结果与使用螺旋桨穿支皮瓣覆盖这类缺陷。材料与方法:选取2015年至2021年在我整形外科行螺旋桨-穿支皮瓣重建的下肢恶性皮肤黑色素瘤患者为研究对象。收集并分析了人口统计学、重建学、肿瘤学和功能数据。结果:22例患者的重建成功率为100%。只有2例患者出现皮瓣远端坏死,并通过局部敷料解决。大多数患者在平均10.1天的时间内实现了快速恢复和早期行走能力。2年总生存率和无进展生存率分别为86.37%和81.82%。结论:采用螺旋桨穿支皮瓣修复下肢肿瘤缺损,手术时间短,恢复快,是一种可靠的选择。它允许保留足够长度和功能的肢体,最小的供体部位发病率和较低的并发症指数,有助于提高患者的生活质量,而不会延迟其他肿瘤治疗。
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引用次数: 0
Impact and Implementation of Plastic Surgery Interest Groups: National Survey of Plastic Surgery Interest Group Leadership. 整形外科兴趣小组的影响和实施:全国整形外科兴趣团体领导调查
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-07-01 DOI: 10.1177/22925503221101955
Nicholas A Elmer, Anamika Veeramani, Natalie Hassell, Eric Shiah, Samuel Manstein, Carly Comer, Valeria Bustos, Samuel J Lin

Background: Plastic surgery interest groups (PSIGs) provide an invaluable opportunity to enhance medical students' exposure to and knowledge of plastic surgery. Despite this, there have been no studies that provide information on the formation of these groups as well as the aspects that make for a productive PSIG. Methods: An anonymous survey was distributed by email via RedCAP to US medical students who hold leadership positions within their medical school's PSIG. Participants were asked baseline medical school information, the structure of their interest group, and perspectives on the most impactful and challenging components of their interest group. Results: Sixteen members (27.6%) of PSIG leadership completed the survey. Eighty percent reported having a membership of greater than 20 students. Fifty percent of the PSIGs were led by advisors who were medical school or hospital-affiliated faculty. Sixty-nine percent of groups were allocated a predetermined amount of money to fund activities and events throughout the academic year. Based on member feedback, groups reported that interactions with plastic surgery faculty, mentorship opportunities, and research opportunities were the most impactful and beneficial components of their PSIG. Forty-four percent reported that the biggest challenge faced by their PSIG was having a small active member group, followed by a lack of funding. Conclusion: Our study provides an in-depth look at the current structure and impact of PSIGs in the United States. It also provides a framework for medical schools that wish to start a PSIG and suggestions for established groups who wish to revitalize their PSIG structure.

背景:整形外科兴趣小组(psig)提供了一个宝贵的机会,以提高医学生对整形外科的接触和知识。尽管如此,还没有研究提供关于这些群体的形成以及构成一个富有成效的PSIG的方面的信息。方法:通过RedCAP向在其医学院PSIG中担任领导职务的美国医学生发送匿名调查。参与者被问及基本的医学院信息、他们兴趣小组的结构,以及对他们兴趣小组中最具影响力和最具挑战性的组成部分的看法。结果:16名PSIG领导成员(27.6%)完成了调查。80%的会员人数超过20人。50%的psig是由医学院或医院附属的教师领导的。69%的小组被分配了一笔预定数额的资金,用于资助整个学年的活动和活动。根据成员的反馈,小组报告说,与整形外科教师的互动、指导机会和研究机会是他们的PSIG中最有影响力和最有益的组成部分。44%的人报告说,他们的PSIG面临的最大挑战是拥有一个小的活跃成员团体,其次是缺乏资金。结论:我们的研究深入了解了美国pigs的当前结构和影响。它还为希望启动PSIG的医学院提供了一个框架,并为希望振兴其PSIG结构的现有团体提供了建议。
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引用次数: 0
Plastic Surgery in the Metaverse. 在超时空做整形手术
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-07-07 DOI: 10.1177/22925503221109714
Nicholas A Elmer, Natalie Hassell, Carly D Comer, Valeria Bustos, Samuel J Lin
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引用次数: 0
Comparison of Negative Pressure Wound Therapy with or without a Split-Thickness Skin Graft in the Surgical Management of Axillary Hidradenitis Suppurativa: A Retrospective Cohort Study. 腋窝化脓性汗腺炎的手术治疗:一项回顾性队列研究:负压伤口治疗加或不加薄皮移植的比较
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-06-27 DOI: 10.1177/22925503221109006
Z Vinnicombe, G V Singh, J Spiers, A L Pouncey, H McEvoy, K Lancaster

Introduction: Negative pressure wound therapy (NPWT) alone or with the addition of a split-thickness skin graft (STSG) are 2 reconstructive options available after surgical excision of axillary hidradenitis suppurativa (HS). The aim of this study was to retrospectively examine patients undergoing these treatments and to assess clinical and patient-related outcome measures. Methods: A single-centre, retrospective analysis was conducted, evaluating surgical excision of axillary HS, with STSG and NPWT, or NPWT alone. Data collected included No. of post-operative clinic visits, time to heal, size of wound, disease recurrence, follow-up time, Dermatology Life Quality Index (DLQI), the Generalised Anxiety Disorder Assessment (GAD-7), the Patient Health Questionnaire Depression Scale (PHQ-9), Pain Visual Analogue Scale (PAINVAS2), the Brief Illness Perception Questionnaire (BIPQ), and Dermatology Visual Analogue Scale (DERMVAS). Two-tailed t-test and Mann-Whitney Wilcoxon U-tests were used to assess for significant relationships. Results: One hundred five patients were included in the study, 44 who received NPWT alone, and 61 who received NPWT + STSG. There was no significant difference in follow-up time (P = .934) or No. of follow-up appointments between groups (P = .287). There was a significant difference in time to heal between groups, with STSG + NPWT observing a mean time of 2.77 months and NPWT alone observing a mean time of 4.40 months (P = .0006). There was no difference in patient-reported outcomes between the 2 groups. Conclusion: There is no difference in patient-reported outcomes with the addition of an STSG to NPWT after surgical excision of HS. Wide excision and use of NPWT alone is an effective procedure for the treatment of axillary HS.

摘要:腋窝化脓性汗腺炎(HS)手术切除后,单用负压创面治疗(NPWT)或联合增厚皮肤移植(STSG)是两种可选择的重建方法。本研究的目的是回顾性检查接受这些治疗的患者,并评估临床和患者相关的结果措施。方法:采用单中心回顾性分析,评价腋窝HS手术切除、STSG联合NPWT或单独NPWT的效果。收集的数据包括:术后就诊次数、愈合时间、伤口大小、疾病复发、随访时间、皮肤病生活质量指数(DLQI)、广泛性焦虑障碍评估(GAD-7)、患者健康问卷抑郁量表(PHQ-9)、疼痛视觉模拟量表(PAINVAS2)、简短疾病感知问卷(BIPQ)、皮肤病视觉模拟量表(DERMVAS)。采用双尾t检验和Mann-Whitney Wilcoxon u检验来评估显著性关系。结果:105例患者纳入研究,其中44例单独接受NPWT, 61例接受NPWT + STSG。两组随访时间差异无统计学意义(P = .934);(P = .287)。两组间愈合时间差异有统计学意义,STSG + NPWT平均时间为2.77个月,NPWT单独治疗平均时间为4.40个月(P = 0.0006)。两组患者报告的结果没有差异。结论:HS手术切除后,在NPWT上添加STSG对患者报告的结果没有影响。广泛切除和单独使用NPWT是治疗腋窝HS的有效方法。
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引用次数: 0
What Technique Results in the Lowest Rate of Velopharyngeal Insufficiency in Patients With Submucous Cleft Palate? A Systematic Review and Meta-Analysis. 什么技术能使黏膜下腭裂患者的口咽功能不全发生率最低?系统综述与荟萃分析
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-07-06 DOI: 10.1177/22925503221110066
Sarah Gardiner, Lindsay Bjornson, Colleen Pawliuk, Marija Bucevska, Jeffrey Bone, Jugpal S Arneja

Objective: To determine which surgical technique offers the lowest rate of velopharyngeal insufficiency (VPI) without the need for further operative intervention, in pediatric patients with nonsyndromic submucous cleft palate (SMCP). Methods: This systematic review and meta-analysis included articles reporting on nonsyndromic pediatric patients treated surgically during childhood for SMCP, with data on postoperative speech outcomes and/or recommendations for secondary surgery. Main outcome measures included rates of unfavorable speech outcomes defined as persistent VPI requiring secondary surgery and speech outcome data. Results: 15 articles met our inclusion criteria, reporting on 383 children who underwent surgical treatment; 343 patients were included in studies reporting recommendations for secondary surgery. There was 1 randomized comparative trial, 4 comparative studies, and 10 single cohort studies. Eight articles used validated speech assessment tools. Our model showed the proportion of patients recommended for secondary surgery varied between techniques, ranging from 0.0% (CI 0.0, 1000) in pharyngeal flap to 17.8% (CI 8.9, 32.5) in straight line repair techniques, but there was no statistically significant difference between treatments (P = .33). Speech improvement ranged from 44.4% to 100%, with 9 studies recommending secondary surgery for some of their patient series. Conclusions: Although not of statistical significance, pharyngeal flap yields the lowest rate of reoperation as a primary technique for pediatric patients with nonsyndromic SMCP. Delayed repair age inherent to SMCP may render operations that rely on a functional levator muscle with less favorable outcomes. The absence of standardized surgical techniques, speech outcomes, speech therapy, and assessment make comparative analysis and recommendation difficult. We advocate for standardized speech assessment tools to improve future quantitative assessment of cleft surgery outcomes and a randomized controlled trial to better elucidate the preferred first-line technique.

目的:探讨在儿童非综合征性粘膜下腭裂(SMCP)患者中,哪种手术技术可提供最低的腭咽功能不全(VPI)发生率,而无需进一步的手术干预。方法:本系统综述和荟萃分析纳入了报告儿童期SMCP手术治疗的非综合征儿童患者的文章,以及术后语言预后和/或二次手术建议的数据。主要结果测量包括需要二次手术的持续性VPI的不良语言结果率和语言结果数据。结果:15篇文章符合我们的纳入标准,报道了383例接受手术治疗的儿童;343名患者被纳入报告二次手术建议的研究。有1项随机比较试验,4项比较研究和10项单队列研究。八篇文章使用了经过验证的语音评估工具。我们的模型显示,推荐二次手术的患者比例在不同的技术之间存在差异,从咽瓣的0.0% (CI 0.0, 1000)到直线修复技术的17.8% (CI 8.9, 32.5),但不同治疗之间没有统计学差异(P = 0.33)。语言改善的范围从44.4%到100%,有9项研究建议对一些患者进行二次手术。结论:咽瓣作为非综合征性SMCP患儿的主要手术手段,其再手术率最低,但无统计学意义。SMCP固有的延迟修复年龄可能导致依赖功能性提上肌的手术预后较差。缺乏标准化的手术技术、语言预后、语言治疗和评估使得比较分析和推荐变得困难。我们提倡使用标准化的语音评估工具来改善未来唇裂手术结果的定量评估,并通过随机对照试验来更好地阐明首选的一线技术。
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引用次数: 0
Ventral Hernia Reconstruction with GORE ENFORM Biomaterial. GORE ENFORM生物材料重建腹侧疝
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-05-01 Epub Date: 2022-08-22 DOI: 10.1177/22925503221120575
Andrew W Hollins, Andrew Atia, Gloria Zhang, Catalin Mateas, Michael Schmidt, Rebecca Fillipo, William W Hope, Howard Levinson

Introduction: Ventral hernia repair (VHR) is one of the most common surgeries performed in the United States. Degradable mesh is the recommended choice for patients presenting with high-risk co-morbidities or increased risk for infection. GORE® ENFORM BiomaterialTM is a biosynthetic degradable mesh that has recently been approved for use in ventral hernia reconstruction with no reports of its clinical outcomes. Methods: This study was a single surgeon case series. Patients were included in the study if they underwent VHR with GORE® ENFORM BiomaterialTM. The decision to use GORE® ENFORM BiomaterialTM was the senior surgeon's decision based on the patient's center for disease control classification. Patient comorbidities, hernia characteristics, postoperative hernia recurrence, and surgical site occurrences (SSOs) were collected at in-patient follow-up appointments and chart review. Patients were asked to complete preoperative and postoperative patient-reported outcomes (PROs) using the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Intensity short form 3a and the hernia-specific quality of life (HerQLes) survey. Results: A total of 15 patients were included in this study. The average length of follow-up was 315 days. Postoperatively, 26.7% of patients had an SSO with 4 surgical site infections. Two patients required an operative washout with mesh removal. One patient experienced hernia recurrence. Eight of the 15 patients completed preoperative and postoperative PROs. Conclusion: This is the first clinical study to report the outcomes of ventral hernia repair using ENFORM mesh. These results show that Enform mesh is an option to consider in complex ventral hernia reconstruction.

腹疝修补术(VHR)是美国最常见的手术之一。可降解补片是推荐的选择,患者呈现高风险合并症或感染风险增加。GORE®ENFORM BiomaterialTM是一种生物合成可降解网状物,最近已被批准用于腹疝重建,尚无临床结果报告。方法:本研究为单外科病例系列研究。如果患者接受GORE®ENFORM BiomaterialTM的VHR,则纳入研究。使用GORE®ENFORM BiomaterialTM的决定是资深外科医生根据患者疾病控制中心的分类做出的决定。患者合并症、疝气特征、术后疝气复发和手术部位发生率(SSOs)在住院随访预约和图表回顾中收集。患者被要求使用患者报告结果测量信息系统(PROMIS)疼痛强度短表3a和疝气特异性生活质量(HerQLes)调查完成术前和术后患者报告结果(PROs)。结果:本研究共纳入15例患者。平均随访时间为315天。术后26.7%的患者发生单点感染并伴有4个手术部位感染。两名患者需要手术冲洗并移除补片。1例患者疝气复发。15例患者中有8例完成了术前和术后的PROs。结论:这是第一个报道使用ENFORM补片修复腹疝的临床研究。这些结果表明,在复杂的腹疝重建中,Enform补片是一种可考虑的选择。
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引用次数: 0
The Impact of Surgical Wait Time and Hospital Stay on the Incidence of Burn Wound Infection and Related Complications at a Single Tertiary Hospital Centre: A 10-Year Experience 一家三级医院中心的手术等待时间和住院时间对烧伤伤口感染及相关并发症发生率的影响:十年经验
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2024-04-29 DOI: 10.1177/22925503241249756
John Milkovich, Isabella F. Churchill, Lucas Gallo, Patrick Kim, Matteo Gallo, Achilles Thoma, Sophocles H. Voineskos, Cheryl Main, Christopher J. Coroneos
Introduction: Admitted patients with burn injuries require prompt treatment and shorter hospital stays to avoid hospital-acquired infections and associated complications. This study aimed to determine the impact of time to the first surgery, and total length of hospital stay on the incidence of BWI and associated complications in adult patients with moderate burn injuries at a single tertiary hospital burn center. Methods: A retrospective chart review identified burn patients admitted to the Burn Unit between January 2011 and January 2021. The incidences of BWI and complications were documented. Univariate logistic regressions were performed, with significance set at P < .05. Results: A total of 171 patients were included in the study. The mean age was 50.8 years (range, 94-18 years), with 64 (37.4%) females. The mean wait time for surgery and total hospital stay was 2.6 days (SD = 2.5; 1-15 days) and 18.6 days (SD = 16.0; 1-125 days), respectively. Precisely, 47 patients (27.5%) were associated with positive burn wound cultures, with 23 patients (13.5%) experiencing clinical burn wound complications. Wait time to surgery did not significantly impact the incidence of BWI (OR = 0.97, P = .72) or related complications (OR = 0.97, P = .61). Total hospital stay was significantly associated with the incidence of BWI (OR = 1.05, P < .001) and related complications (OR = 1.02, P = .03). Conclusions: Delay to surgery may not be a significant risk factor of BWI and related complications in patients with burn injuries. Half of positive burn wound cultures are associated with objective clinical infection and subsequent complications. However, total hospital stay may be clinically important.
导言:入院的烧伤患者需要及时治疗和缩短住院时间,以避免院内感染和相关并发症。本研究旨在确定在一家三甲医院烧伤中心就诊的中度烧伤成人患者中,首次手术时间和总住院时间对BWI和相关并发症发生率的影响。方法通过回顾性病历审查,确定了 2011 年 1 月至 2021 年 1 月期间入住烧伤科的烧伤患者。记录了BWI和并发症的发生率。进行单变量逻辑回归,显著性设定为 P < .05。结果:共有 171 名患者参与了研究。平均年龄为 50.8 岁(94-18 岁),女性 64 人(37.4%)。平均手术等待时间和总住院时间分别为 2.6 天(SD = 2.5;1-15 天)和 18.6 天(SD = 16.0;1-125 天)。确切地说,47 名患者(27.5%)烧伤创面培养呈阳性,23 名患者(13.5%)出现临床烧伤创面并发症。手术等待时间对BWI(OR = 0.97,P = .72)或相关并发症(OR = 0.97,P = .61)的发生率无明显影响。总住院时间与BWI(OR = 1.05,P = .001)和相关并发症(OR = 1.02,P = .03)的发生率有明显关系。结论:延迟手术可能不是烧伤患者发生 BWI 和相关并发症的重要风险因素。一半的烧伤创面培养阳性与客观的临床感染和后续并发症有关。不过,总住院时间可能对临床很重要。
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Plastic surgery
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