Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.651845
D.S. Hsu, C. Riviere, N. Thakor
An adaptive filter designed to cancel pathological tremor in computer pen input is tested on-line. The adaptive filter, called the WFLC (weighted-frequency Fourier linear combiner) filter, estimates tremor frequency as well as amplitude and then cancels the tremor. The WFLC algorithm was implemented into pen driver software and tested with subjects with pathological tremor. A standard low-pass filter which is commonly used to attenuate tremor was also tested and compared with the WFLC filter. Tests were conducted through a series of quantitative target objectives. Best results were obtained when the WFLC filter was used.
{"title":"On-line canceling of pathological tremor for computer interface","authors":"D.S. Hsu, C. Riviere, N. Thakor","doi":"10.1109/IEMBS.1996.651845","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.651845","url":null,"abstract":"An adaptive filter designed to cancel pathological tremor in computer pen input is tested on-line. The adaptive filter, called the WFLC (weighted-frequency Fourier linear combiner) filter, estimates tremor frequency as well as amplitude and then cancels the tremor. The WFLC algorithm was implemented into pen driver software and tested with subjects with pathological tremor. A standard low-pass filter which is commonly used to attenuate tremor was also tested and compared with the WFLC filter. Tests were conducted through a series of quantitative target objectives. Best results were obtained when the WFLC filter was used.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"41 1","pages":"521-522 vol.2"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77662617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.656945
Q. Bai, K. Wise, J. Hetke, D. Anderson
A practical microassembly process has been developed to create three-dimensional (3D) microelectrode arrays for recording and stimulation in the central nervous system using micromachined 2D probe components. Orthogonal lead transfers between the probes and a cortical surface platform are formed by attaching gold beams on the probes to pads on the platform using wire-free ultrasonic bonding. The low-profile (150 /spl mu/m) outrigger design of the probes allows the bonding of fully-assembled high-density arrays. Micromachined microtools allow full array assembly in about 30 minutes. Arrays having up to 8/spl times/16-shanks on 200 /spl mu/m centers have been realized and used to record cortical single units successfully. Dynamic insertion devices have also been explored to allow the implantation of these high-density probe arrays into feline cortex at high speed.
{"title":"A microassembly structure for intracortical three-dimensional electrode arrays","authors":"Q. Bai, K. Wise, J. Hetke, D. Anderson","doi":"10.1109/IEMBS.1996.656945","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.656945","url":null,"abstract":"A practical microassembly process has been developed to create three-dimensional (3D) microelectrode arrays for recording and stimulation in the central nervous system using micromachined 2D probe components. Orthogonal lead transfers between the probes and a cortical surface platform are formed by attaching gold beams on the probes to pads on the platform using wire-free ultrasonic bonding. The low-profile (150 /spl mu/m) outrigger design of the probes allows the bonding of fully-assembled high-density arrays. Micromachined microtools allow full array assembly in about 30 minutes. Arrays having up to 8/spl times/16-shanks on 200 /spl mu/m centers have been realized and used to record cortical single units successfully. Dynamic insertion devices have also been explored to allow the implantation of these high-density probe arrays into feline cortex at high speed.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"84 1","pages":"264-265 vol.1"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79456038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.651967
K. Cheng, Bae-horng Chen, Han-Seng Tong
In this paper, a genetic based reconstruction algorithm (GA) is proposed for producing the electrical impedance image. This method has the potential in parallelized hardware implementation. The impedance image reconstruction is cast as a minimization problem. The cost function is defined as the errors between the measured and estimated boundary voltages in least square sense. The image is considered as the bit strings. From the results, it is demonstrated to be feasible for producing the dynamic image. In order to reduce the number of degrees of freedom of this proposed method, a guided technique based upon the voltage measurements is also designed. In addition, the noise effect of the voltage measurement is also investigated. From the simulation results, the proposed algorithm has the some extent of the noise immunity.
{"title":"Electrical impedance image reconstruction using the genetic algorithm","authors":"K. Cheng, Bae-horng Chen, Han-Seng Tong","doi":"10.1109/IEMBS.1996.651967","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.651967","url":null,"abstract":"In this paper, a genetic based reconstruction algorithm (GA) is proposed for producing the electrical impedance image. This method has the potential in parallelized hardware implementation. The impedance image reconstruction is cast as a minimization problem. The cost function is defined as the errors between the measured and estimated boundary voltages in least square sense. The image is considered as the bit strings. From the results, it is demonstrated to be feasible for producing the dynamic image. In order to reduce the number of degrees of freedom of this proposed method, a guided technique based upon the voltage measurements is also designed. In addition, the noise effect of the voltage measurement is also investigated. From the simulation results, the proposed algorithm has the some extent of the noise immunity.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"4 1","pages":"768-769 vol.2"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80980071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.646506
D. Sherman, Y. Tsai, L. Rossell, M. Mirski, N. Thakor
A new method of measuring coherence between EEG channels is proposed for modeling the level of linear association during epileptic seizures. This method relies upon modelling the clonic seizure activity as a sum of sinusoids. The authors estimate contributions from correlated and uncorrelated sinusoidal components from information contained in auto- and cross-correlation matrices. Coherence estimates are formed from the ratio of correlated to total power. The authors illustrate the value of this method by examination of the strength of correlation between seizure EEG from specific thalamic nuclei and cortex in an animal model of generalized epilepsy.
{"title":"A thalamus-to-cortex seizure pathway: a new coherence approach using sinusoidal modelling","authors":"D. Sherman, Y. Tsai, L. Rossell, M. Mirski, N. Thakor","doi":"10.1109/IEMBS.1996.646506","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.646506","url":null,"abstract":"A new method of measuring coherence between EEG channels is proposed for modeling the level of linear association during epileptic seizures. This method relies upon modelling the clonic seizure activity as a sum of sinusoids. The authors estimate contributions from correlated and uncorrelated sinusoidal components from information contained in auto- and cross-correlation matrices. Coherence estimates are formed from the ratio of correlated to total power. The authors illustrate the value of this method by examination of the strength of correlation between seizure EEG from specific thalamic nuclei and cortex in an animal model of generalized epilepsy.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"5 1","pages":"2222-2223 vol.5"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81847008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.652832
P. Kerkhof, E. Pijnenburg
The aim of this study is to analyze how the End-Systolic Pressure-Volume Relationship (ESPVR) depends on ventricular volume in the diseased left ventricle. Ventricular end-systolic elastance (Emax) varies with the prevailing values of ejection pressure (ESP), end-systolic volume (ESV), and an unstressed volume term (Vo). Measurements on humans as reported in the literature are used to investigate the full range of this relationship. The authors' results indicate that considering Emax alone, as is usually done in clinical practice, is an insufficient approach to characterize ventricular function. Rather the authors propose to consider the easily attainable yet more powerful index ESV. Interestingly, ESV is also significantly correlated with the term (ESV-Vo), suggesting that ESV in itself already embodies information on this elementary index Vo.
{"title":"Determinants of end-systolic elastance of the left ventricle and their relationship with volumetric indices","authors":"P. Kerkhof, E. Pijnenburg","doi":"10.1109/IEMBS.1996.652832","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.652832","url":null,"abstract":"The aim of this study is to analyze how the End-Systolic Pressure-Volume Relationship (ESPVR) depends on ventricular volume in the diseased left ventricle. Ventricular end-systolic elastance (Emax) varies with the prevailing values of ejection pressure (ESP), end-systolic volume (ESV), and an unstressed volume term (Vo). Measurements on humans as reported in the literature are used to investigate the full range of this relationship. The authors' results indicate that considering Emax alone, as is usually done in clinical practice, is an insufficient approach to characterize ventricular function. Rather the authors propose to consider the easily attainable yet more powerful index ESV. Interestingly, ESV is also significantly correlated with the term (ESV-Vo), suggesting that ESV in itself already embodies information on this elementary index Vo.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"23 1","pages":"1322-1323 vol.3"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87224440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.656974
B. Familoni, T. Abell, D. Nemoto, G. Voeller, B. Johnson
Electrical stimulation or pacing of the stomach has been advocated as a possible treatment for gastric motor dysfunction. To date, researchers have employed frequencies similar to, or slightly higher than the native electrical control activity frequency in gastric stimulation with little success. In the present study, the efficacy of electrical stimulation at frequencies ranging from 3 to 30 cycles/min was investigated in a dog model. The study compared the relative efficiency of the "low-frequency" stimulating signal (3 to 9 cycles/min) versus the "high-frequency" signal (20 and 30 cycles/min) in generating contractions.
{"title":"A canine model of gastric electrical stimulation","authors":"B. Familoni, T. Abell, D. Nemoto, G. Voeller, B. Johnson","doi":"10.1109/IEMBS.1996.656974","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.656974","url":null,"abstract":"Electrical stimulation or pacing of the stomach has been advocated as a possible treatment for gastric motor dysfunction. To date, researchers have employed frequencies similar to, or slightly higher than the native electrical control activity frequency in gastric stimulation with little success. In the present study, the efficacy of electrical stimulation at frequencies ranging from 3 to 30 cycles/min was investigated in a dog model. The study compared the relative efficiency of the \"low-frequency\" stimulating signal (3 to 9 cycles/min) versus the \"high-frequency\" signal (20 and 30 cycles/min) in generating contractions.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"80 1","pages":"323-324 vol.1"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86147665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.652828
J.K. Li, Y. Zhu, J. Wang, H. Pijnenburg, P. Kerkhof
The pressure-dependent compliance and viscoelastic characteristics of arteries can be observed from experimentally determined pressure-diameter relations. These relations reveal the limitations in the use of linear arterial system models for the determination of systemic arterial compliance for the purpose of evaluating the dynamic load of the left ventricle.
{"title":"Pressure-diameter relation and linear model derived systemic arterial compliance","authors":"J.K. Li, Y. Zhu, J. Wang, H. Pijnenburg, P. Kerkhof","doi":"10.1109/IEMBS.1996.652828","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.652828","url":null,"abstract":"The pressure-dependent compliance and viscoelastic characteristics of arteries can be observed from experimentally determined pressure-diameter relations. These relations reveal the limitations in the use of linear arterial system models for the determination of systemic arterial compliance for the purpose of evaluating the dynamic load of the left ventricle.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"9 1","pages":"1314-1315 vol.3"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81958364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.647651
S. Honda, Y. Tornita, T. Suzuki
With a generalized method of projections onto convex sets (g-POCS), a distribution of peripheral nerve conduction velocities and a single fiber action potential are deconvolved from two compound action potentials, which are evoked at two stimulating sites, and observed with a surface electrode. The iterative estimation procedure consists of alternating projections of each least square solution onto corresponding constraint set; a non-negative distribution with finite support and a single fiber action potential with finite duration are assumed. The proposed method is applied to measure the distribution of the conduction velocities, and compared with the collision method, resulting high correlation. The method is also applied to measure the distribution of the sensory nerve conduction velocities. The useful information about the peripheral nerve can be obtained by the present method and the application to the clinical field is expected.
{"title":"Estimation of conduction velocity distribution in human nerve trunks with generalized POCS method","authors":"S. Honda, Y. Tornita, T. Suzuki","doi":"10.1109/IEMBS.1996.647651","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.647651","url":null,"abstract":"With a generalized method of projections onto convex sets (g-POCS), a distribution of peripheral nerve conduction velocities and a single fiber action potential are deconvolved from two compound action potentials, which are evoked at two stimulating sites, and observed with a surface electrode. The iterative estimation procedure consists of alternating projections of each least square solution onto corresponding constraint set; a non-negative distribution with finite support and a single fiber action potential with finite duration are assumed. The proposed method is applied to measure the distribution of the conduction velocities, and compared with the collision method, resulting high correlation. The method is also applied to measure the distribution of the sensory nerve conduction velocities. The useful information about the peripheral nerve can be obtained by the present method and the application to the clinical field is expected.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"17 1","pages":"1764-1765 vol.4"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85721387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.646255
K. Momose, K. Komiya, A. Uchiyama
In order to investigate the characteristics of luminance channels in the human color visual system, the binary kernel method was applied to VEPs elicited by luminance-modulated stimuli of constant chromaticity. Binary kernels of VEPs measured from normal subjects were estimated, and the relationship between the waveforms of kernels and stimuli was examined. The results showed that the waveforms of kernels were independent of the chromaticity of stimuli, and that they reflected the characteristics of the luminance channel. Since binary kernels up to the 3rd order were typical, the luminance-VEP system can be described by a 3rd-order nonlinear system. Waveforms of 1st- and 2nd order kernels depended on the mean luminance and contrast of the stimulus, and the amplitudes of 3rd-order kernels increased according to contrast.
{"title":"Binary kernels of VEPs elicited by luminance-modulated stimuli","authors":"K. Momose, K. Komiya, A. Uchiyama","doi":"10.1109/IEMBS.1996.646255","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.646255","url":null,"abstract":"In order to investigate the characteristics of luminance channels in the human color visual system, the binary kernel method was applied to VEPs elicited by luminance-modulated stimuli of constant chromaticity. Binary kernels of VEPs measured from normal subjects were estimated, and the relationship between the waveforms of kernels and stimuli was examined. The results showed that the waveforms of kernels were independent of the chromaticity of stimuli, and that they reflected the characteristics of the luminance channel. Since binary kernels up to the 3rd order were typical, the luminance-VEP system can be described by a 3rd-order nonlinear system. Waveforms of 1st- and 2nd order kernels depended on the mean luminance and contrast of the stimulus, and the amplitudes of 3rd-order kernels increased according to contrast.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"39 1","pages":"1786-1787 vol.5"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85739698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1996-12-01DOI: 10.1109/IEMBS.1996.647542
W. Finn, P. Lopresti
The current project seeks to address the problem of constructing models with which to guide the development and evaluation of retinal prosthesis designs. In particular, the efforts described in this paper are intended to develop a more complete understanding of how electrical stimulation of ganglion cells by external electrodes interacts with retinal surface tissues, and how specific stimuli are encoded by the retinal and optic nerve processing systems. Toward this end, novel surgical techniques, optic tecturm recording from live animals, correlational analysis, and systematic electrophysiological recording of stimulation are utilized. Microsurgical methods for providing a repeatable, chronic implantation of stimulating prostheses have been developed. An optoelectronic processor capable of reliably encoding wavelength-dependent intensity information, including sensitivity changes with light adaptation has also been constructed.
{"title":"An amphibian model for developing and evaluating retinal prostheses","authors":"W. Finn, P. Lopresti","doi":"10.1109/IEMBS.1996.647542","DOIUrl":"https://doi.org/10.1109/IEMBS.1996.647542","url":null,"abstract":"The current project seeks to address the problem of constructing models with which to guide the development and evaluation of retinal prosthesis designs. In particular, the efforts described in this paper are intended to develop a more complete understanding of how electrical stimulation of ganglion cells by external electrodes interacts with retinal surface tissues, and how specific stimuli are encoded by the retinal and optic nerve processing systems. Toward this end, novel surgical techniques, optic tecturm recording from live animals, correlational analysis, and systematic electrophysiological recording of stimulation are utilized. Microsurgical methods for providing a repeatable, chronic implantation of stimulating prostheses have been developed. An optoelectronic processor capable of reliably encoding wavelength-dependent intensity information, including sensitivity changes with light adaptation has also been constructed.","PeriodicalId":20427,"journal":{"name":"Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"11 1","pages":"1540-1541 vol.4"},"PeriodicalIF":0.0,"publicationDate":"1996-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87450551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：