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Knowledge-based medical image registration 基于知识的医学图像配准
Hui-Hua Wen, Wei-Chung Lin, Chin-Tu Chen
Describes a new framework for surface-based medical image registration. By implementing a fuzzy logic system, this method allows the incorporation of human expert knowledge to evaluate the confidence level of two matching points using their multiple local image properties such as gradient direction and curvature. The proposed technique can be applied to both intra- and inter-subject medical image registration. It can also relax the performance requirement on the contour extraction process.
描述了一种新的基于表面的医学图像配准框架。通过实现模糊逻辑系统,该方法允许结合人类专家知识,利用两个匹配点的多个局部图像属性(如梯度方向和曲率)来评估其置信度。该方法可应用于医学图像的学科间配准和学科内配准。它还可以放宽对轮廓提取过程的性能要求。
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引用次数: 7
Measurement of shear waves in tissue 组织中剪切波的测量
J. Greenleaf, V. Dutt, R. Muthupillai, A. Manduca, R. Ehman
The wavelength of a propagating pulse of shear wave within tissue is related to the local shear modulus and density through the speed of propagation. If the pulse does not produce standing waves, then the wavelength is a function of the tissue properties and not boundary conditions. Methods for imaging such waves using ultrasound and magnetic resonance imaging have recently been developed. The MRI method, termed Magnetic Resonance Elastography, can measure displacements in all three dimensions and is sensitive to motion of the order of 100 nanometers. The ultrasound method can measure in one plane very quickly and is sensitive to displacements of fractions of micrometers. Local wavelength of the propagating shear waves can be measured using specially modified filters. Shear modulus can then be estimated if density is known or assumed. Applications of this method reminiscent of palpation but in three dimensions and at any depth in the tissue are possibilities.
剪切波脉冲在组织内的传播波长通过传播速度与局部剪切模量和密度有关。如果脉冲不产生驻波,那么波长是组织特性的函数,而不是边界条件的函数。利用超声和磁共振成像对这种波进行成像的方法最近得到了发展。MRI方法,称为磁共振弹性成像,可以测量所有三个维度的位移,并且对100纳米量级的运动很敏感。超声方法可以在一个平面内快速测量,并且对微米级的位移敏感。用特殊改良的滤光片可以测量传播的横波的局部波长。如果密度已知或假设,则可以估计剪切模量。这种方法的应用让人想起触诊,但在三维和任何深度的组织是可能的。
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引用次数: 2
A combination of AR and neural network technique for EMG pattern identification 结合AR和神经网络技术的肌电模式识别
A. Asres, H. Dou, Zhaoying Zhou, Yuli Zhang, Sencun Zhu
The EMG data acquired during voluntary movement of the active muscles of the disabled may provide useful control commands and information in functional electrical stimulation or in artificial prosthesis provided that the raw EMG data are property processed and identified. This technique may be used by the patients to transfer commands to their paralyzed extremities or artificial limbs. Combination of autoregressive and neural network technique to identify various functional hand movements is proposed. Functional hand movements such as palmar flexion and dorsiflexion, wrist pronation and supination, wrist flexion and extension, are identified. A fourth order parametric model is employed to evaluate the set of coefficients. The coefficients are then used as input for the neural network to identify the functional movement. Experiment was done on three healthy individuals and the rate of identification is shown to be adequate to be used in the development of either neural prostheses or artificial limbs.
在残疾人主动肌肉运动过程中获得的肌电图数据可以为功能性电刺激或人工假体提供有用的控制命令和信息,前提是原始肌电图数据经过适当处理和识别。这项技术可用于病人将指令传递给瘫痪的肢体或假肢。提出了将自回归与神经网络相结合的方法来识别各种手部功能动作。功能性手部运动,如手掌屈曲和背屈,手腕旋前和旋后,手腕屈曲和伸展,被识别。采用四阶参数模型对系数集进行求解。然后将这些系数作为神经网络的输入来识别功能运动。在三个健康个体上进行的实验表明,识别率足以用于神经假体或假肢的开发。
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引用次数: 23
Extraction of brain tissues by non-parametric region growing method 非参数区域生长法提取脑组织
M. Yanase, M. Hasegawa, T. Ikeguchi, T. Matozaki
It is desirable to process the brain images by computers in order to extract brain region from MRI. When these method are applied to MRI, it has been necessary to experimentally decide parameters in order to get best performances. In this paper, we propose a novel algorithm for the automatic extraction of brain tissues from MRI. This algorithm is called the non-parametric region growing (NPRG) method which does not need the parameter. By NPRG, we can get the same extracted brain regions as the conventional method that has to experimentally decide the parameters.
为了从MRI中提取脑区,需要对脑图像进行计算机处理。当这些方法应用于MRI时,为了获得最佳的性能,必须通过实验确定参数。在本文中,我们提出了一种新的从MRI中自动提取脑组织的算法。该算法不需要参数,称为非参数区域生长法(NPRG)。通过NPRG,我们可以得到与传统方法相同的提取脑区域,但必须通过实验确定参数。
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引用次数: 2
Active wireless electrodes for surface electromyography 用于表面肌电图的有源无线电极
M. Ohyama, Y. Tomita, S. Honda, H. Uchida, N. Matsuo
An active electrode with a built-in transmitter (named wireless electrode) is presented, which derives surface EMG without any skin preparation and conductive paste due to impedance transforming. Subjects are less restricted with the present wireless electrode than with the conventional telemetry system because of no connecting wires between the electrode and the transmitter. Moreover, it is not affected by noise caused by the movement of wires.
提出了一种内置变送器的有源电极(称为无线电极),该电极无需任何皮肤制备和阻抗转换的导电膏即可获得表面肌电信号。由于在电极和发射器之间没有连接线,受试者使用本发明的无线电极比使用传统遥测系统受到的限制更少。此外,它不受电线运动产生的噪音的影响。
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引用次数: 8
The design of a portable fetal heart rate and uterine contraction monitor 便携式胎儿心率和子宫收缩监测仪的设计
Chih-lung Lin, Tz-Yi Liu, Han-Chang Wu, S. Young, Maw-huei Lee, T. Kuo
A new portable fetal heart rate (FHR) and uterine contraction (UC) monitor has been developed. The system is portable, light weight, small size, battery powered. It provides a predetermined "long-term" monitoring, and stores abnormal data. Only one 9 V commercial battery is used for the whole system, so it could be used safely by the high risk pregnant woman to monitor the abnormal FHR and UT activities, when she is not in the hospital. When the microprocessor-based system detects a predetermined "long-term" abnormal activity, it can activate the appropriate alarm to advise the pregnant woman to go to hospital as soon as possible. The abnormal data from the monitor are not transmitted to the hospital's personal computer till the pregnant woman receives medical treatment. A PC-based software to display the long-term abnormal FHR and UT data from the portable monitor by using window figures or graphs has also been provided, and these figures could help clinical doctors make diagnoses.
研制了一种新型便携式胎儿心率(FHR)和子宫收缩(UC)监护仪。该系统便于携带,重量轻,体积小,由电池供电。它提供预定的“长期”监控,并存储异常数据。整个系统只使用一个9v商用电池,因此高危孕妇在不住院的情况下,可以安全使用,监测异常的FHR和UT活动。当基于微处理器的系统检测到预定的“长期”异常活动时,它可以激活适当的警报,建议孕妇尽快去医院。在孕妇接受治疗之前,监视器上的异常数据不会传输到医院的个人计算机上。本文还提供了一种基于pc的软件,以窗口图形或图形的方式显示便携式监护仪的长期异常FHR和UT数据,这些数据可以帮助临床医生进行诊断。
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引用次数: 6
Bispectral analysis of EEG burst patterns from piglets during recovery from asphyxia 仔猪窒息恢复期脑电图爆发模式的双谱分析
J. Muthuswamy, D. Sherman, N. Thakor
The aim of this study was to study phase coupling among different frequency components in EEC burst patterns observed in piglets during recovery from asphyxia and to compare them with those of the awake baseline EEG data. Phase coupling was quantitated by determining the average bicoherence index within the delta band along the main diagonal in the bifrequency plane. Multiple instances of burst patterns from each experiment were analyzed for phase coupling and compared with the corresponding baseline EEG data. The baseline EEG data did not show any significant phase coupling within the delta band of frequencies in any of the experiments. The raw averaged bicoherence indices within the delta band of bursts was higher than that of corresponding baseline in almost all instances. The authors, therefore, conclude that the delta frequency components of the EEG tend to become more phase coupled during the initial phase of recovery of the brain from an asphyxic injury.
本研究的目的是研究仔猪在窒息恢复期间观察到的脑电图爆发模式中不同频率成分的相位耦合,并将其与清醒基线脑电图数据进行比较。通过测量双频平面上沿主对角线的δ波段内的平均双相干指数来定量相位耦合。对每个实验的多个突发模式实例进行相位耦合分析,并与相应的基线EEG数据进行比较。基线EEG数据在任何实验中都没有显示出任何显著的δ频带内的相位耦合。在几乎所有情况下,脉冲δ带内的原始平均双相干指数都高于相应的基线。因此,作者得出结论,在大脑从窒息性损伤恢复的初始阶段,脑电图的δ频率成分倾向于变得更加相位耦合。
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引用次数: 3
A validation study of stroke volume measurement by means of electrical impedance tomography 电阻抗断层成像测量脑行程容积的验证研究
A. Janse, A. Vonk Noordegraaf, J. T. Marcus, R. Heethaar, P. Postmus, T. Faes, P. de Vries
ECG-gated electrical impedance tomography (EIT) has been developed to monitor blood volume changes. The aim of this study was to compare stroke volume measurements by EIT with established methods of thermodilution and magnetic resonance imaging (MRI). After right cardiac catheterization, EIT measurements were performed in 26 patients. Regression analysis was used to analyze the relation between the EIT results and stroke volume. From the regression line an equation was derived to estimate stroke volume (in ml) by EIT. In a group of eleven healthy subjects this equation was validated to MRI. A strong correlation was found between EIT and stroke volume measured by the thermodilution method (r=0.86). The reproducibility coefficient for EIT measurements was 0.98. The average standard deviation between stroke volume measured by EIT and MRI is 5.4 ml, the mean difference between both methods is 0.7 ml and the coefficient of variation is 8.4%. We conclude that EIT is a valid and reproducible method for the assessment of stroke volume in healthy controls and cardiological patients.
心电图门控电阻抗断层扫描(EIT)已经发展到监测血容量的变化。本研究的目的是比较脑电成像与热稀释和磁共振成像(MRI)的既定方法的脑卒中体积测量。26例患者右心导管置管后进行EIT测量。采用回归分析分析EIT结果与脑划量之间的关系。从回归线推导出EIT估算笔划体积(ml)的方程。在一组11名健康受试者中,该方程被核磁共振验证。热稀释法测得EIT与脑卒中容积之间有很强的相关性(r=0.86)。EIT测量的重现系数为0.98。脑电成像与MRI测量的脑卒中容积的平均标准差为5.4 ml,两者的平均差值为0.7 ml,变异系数为8.4%。我们得出结论,EIT是一种有效的、可重复的方法,用于评估健康对照和心脏病患者的脑卒中容量。
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引用次数: 0
Electro-oculography mouse for amyotrophic lateral sclerosis patients 肌萎缩性侧索硬化症患者眼电扫描小鼠
Y. Tomita, Y. Igarashi, S. Honda, N. Matsuo
Severe amyotrophic lateral sclerosis (ALS) patients cannot move their muscles, and sometimes even respiratory muscles are affected so that they are obliged to mount artificial respiratory devices. Of course, patients of this severity stage cannot speak. These patients' remaining motor function consists of eye movement. Thus, the communication means for these patients is via their eye movement. Patients have previously used a transparent alphabetic table. But this is cumbersome for both the patients and the help givers, and it is also time consuming. A computer mouse whose cursor can be controlled by eye movement has been developed. The eye movement is detected by electro-oculography, and its click is realized by a voluntary blinking. By pointing a cursor to a specified letter on an alphabetic table on a monitor screen, a patient can describe his/her intention. This method has been found to be useful for severe ALS patients.
严重的肌萎缩性侧索硬化症(ALS)患者无法活动肌肉,有时甚至呼吸肌也受到影响,因此他们不得不安装人工呼吸装置。当然,这个严重阶段的病人不能说话。这些病人剩下的运动功能包括眼球运动。因此,这些病人的交流方式是通过他们的眼球运动。患者以前使用的是透明的字母表。但这对病人和提供帮助的人来说都很麻烦,而且也很耗时。一种可以通过眼球运动控制光标的电脑鼠标已经研制成功。眼球运动由眼电术检测,眼球的点击是通过自发的眨眼来实现的。通过将光标指向显示器屏幕上的字母表上的指定字母,患者可以描述他/她的意图。这种方法已被发现对严重的ALS患者是有用的。
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引用次数: 17
Adaptive cancellation of the pacing stimulus artifact in the gastric myoelectrical recordings 自适应消除胃肌电记录中的起搏刺激伪影
Zhiyue Lin, J. Chen, R. Mccallum
To evaluate the effects of gastric pacing, several electrodes are usually placed on the serosal surface of the stomach along the greater curvature so that one can be used for delivering electrical currents and others for recording gastric myoelectrical activity. One of problems with these recordings is the pacing stimulus artifact superimposed on the natural gastric myoelectrical signals which make it difficult to analyze accurately. This paper presents an effective transform-domain adaptive filtering method for the cancellation of the pacing stimulus artifact in the gastric myoelectrical signals obtained through serosal electrodes during gastric pacing. Results from both simulations and real signals demonstrated that the pacing stimulus artifact could be effectively canceled while the natural gastric myoelectrical signal was not affected by adaptive filtering.
为了评估胃起搏的效果,通常在胃的浆膜表面沿大弯曲放置几个电极,这样一个电极可以用于输送电流,另一个电极用于记录胃肌电活动。这些记录的问题之一是与自然胃肌电信号叠加的起搏刺激伪影,使其难以准确分析。本文提出了一种有效的变换域自适应滤波方法,用于消除胃起搏过程中浆膜电极获取的肌电信号中的起搏刺激伪影。仿真和实际信号的结果表明,自适应滤波可以有效地消除起搏刺激伪影,同时不影响自然肌电信号。
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引用次数: 3
期刊
Proceedings of 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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