Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1638378
Ruchi Kohli, Anu Mittal, A. Mittal
The hydrogen-bonded dimers and 1:1 complexes formed between glyoxylic acid (GA) and H2O have been investigated employing computational techniques like Natural Bond Orbital (NBO) analysis and Atoms in Molecules (AIM) etc. All calculations are carried at B3LYP/6-311++G** level. Seven dimers and four monohydrates are located on the potential energy surface (PES) each for intramolecular hydrogen bonding (IHB) stabilized G3 and non-IHB stabilized rotamer G1. The most stable dimer and hydrate are formed by non-IHB stabilized rotamer G1. In the most stable dimer, two GA units interact in a duo of C=O…H-O hydrogen bonds forming an eight-membered ring structure. In most stable hydrate, H2O acts as a hydrogen bond acceptor and GA acts as an HB donor. The stabilization energies are calculated and the effect of basis set superposition errors (BSSE) is also considered. A good correlation is found between S.E. and the sum of AIM electron densities at bond critical points for both dimers and hydrates. The gas phase hydration and clustering of GA drive new particle formation for atmospheric aerosols, which affect climate, weather, and human health, hence the study has a significant environmental concern.
{"title":"DIMERIZATION AND HYDRATION OF GLYOXYLIC ACID: A COMPUTATIONAL STUDY","authors":"Ruchi Kohli, Anu Mittal, A. Mittal","doi":"10.31788/rjc.2023.1638378","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638378","url":null,"abstract":"The hydrogen-bonded dimers and 1:1 complexes formed between glyoxylic acid (GA) and H2O have been investigated employing computational techniques like Natural Bond Orbital (NBO) analysis and Atoms in Molecules (AIM) etc. All calculations are carried at B3LYP/6-311++G** level. Seven dimers and four monohydrates are located on the potential energy surface (PES) each for intramolecular hydrogen bonding (IHB) stabilized G3 and non-IHB stabilized rotamer G1. The most stable dimer and hydrate are formed by non-IHB stabilized rotamer G1. In the most stable dimer, two GA units interact in a duo of C=O…H-O hydrogen bonds forming an eight-membered ring structure. In most stable hydrate, H2O acts as a hydrogen bond acceptor and GA acts as an HB donor. The stabilization energies are calculated and the effect of basis set superposition errors (BSSE) is also considered. A good correlation is found between S.E. and the sum of AIM electron densities at bond critical points for both dimers and hydrates. The gas phase hydration and clustering of GA drive new particle formation for atmospheric aerosols, which affect climate, weather, and human health, hence the study has a significant environmental concern.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1638350
Aieshri Swargiary
Benzylamine to imine conversion through oxidative coupling reaction has been achieved with almost 91% yield under very mild conditions by applying a one-dimensional coordination polymer as a catalyst and tert-butyl hydroperoxide (TBHP) as an oxidizing agent. The 1D-coordination polymer, [{Cu2(2,3-pydc)2(2,2ʹ-bpy) (H2O)2}.4H2O]n(A) has been re-synthesized by different synthetic process using the ligands 2,3- pyridinedicarboxylic acid (2,3-pydc) and 2,2Ꞌ-bipyridine (2,2Ꞌ-bpy) and it has been characterized by utilizing different physicochemical techniques such as IR-spectroscopy, UV-Vis spectroscopy, elemental analysis and TGDTA analysis including reestablishment of X-ray single crystal structure. The proposed mechanism of the reaction indicates that the catalytic reaction is facilitated by a flexible and coordinatively unsaturated Cu(II) center and through the formation of tert-butyl peroxy radical.
{"title":"EXPLORATION OF COPPER-BASED COORDINATION POLYMER AS CATALYST: HIGH YIELD OXIDATIVE COUPLING OF BENZYLAMINE TO IMINE","authors":"Aieshri Swargiary","doi":"10.31788/rjc.2023.1638350","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638350","url":null,"abstract":"Benzylamine to imine conversion through oxidative coupling reaction has been achieved with almost 91% yield under very mild conditions by applying a one-dimensional coordination polymer as a catalyst and tert-butyl hydroperoxide (TBHP) as an oxidizing agent. The 1D-coordination polymer, [{Cu2(2,3-pydc)2(2,2ʹ-bpy) (H2O)2}.4H2O]n(A) has been re-synthesized by different synthetic process using the ligands 2,3- pyridinedicarboxylic acid (2,3-pydc) and 2,2Ꞌ-bipyridine (2,2Ꞌ-bpy) and it has been characterized by utilizing different physicochemical techniques such as IR-spectroscopy, UV-Vis spectroscopy, elemental analysis and TGDTA analysis including reestablishment of X-ray single crystal structure. The proposed mechanism of the reaction indicates that the catalytic reaction is facilitated by a flexible and coordinatively unsaturated Cu(II) center and through the formation of tert-butyl peroxy radical.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2021.1618165
N. Rani, P. Pavani, Chebolu Naga Sesha Sai Pavan Kumar, Satwinder Singh Marok, S. Tulasi
Water pollution has recently become a serious global problem and hence researchers were focusing to develop innovative methods for the purification of water and then getting access to purified water by reducing pollution. As a result, the current study concentrated on synthesizing cobalt-doped zinc oxide nanoparticles by accumulating cobalt ions on Pistia (Pistiastratiotes L.) plant tissue and combining them with zinc acetate precursor. Further, the synthesized particles were analyzed for their efficiency in photo-desulphurization of organo sulphur compounds such as Dibenzothiophene and 2,5-dimethyl thiophene. Various characterization studies proved that the nanoparticles were oval in shape and had particle sizes of 8-34 nm and the particles were distributed with less aggregation. The particles have 47 % of zinc element and 21% cobalt with hexagonal (wurtzite) crystalline structure. The synthesized Co-doped ZnO nanoparticles were utilized for the desulfurization of Sulphur containing pollutants such as dibenzothiophene and 2,5-dimethyl thiophene. The results proved that rapid desulfurization was observed during the initial time of the study. The % desulfurization of 14.36±0.136 and 19.63±0.201% was observed within 5 min of the study for dibenzothiophene and 2,5-dimethyl thiophene. Whereas the high % desulfurization was noticed within less time of 25 min wherein the % desulfurization was observed to be 95.61±0.279 and 93.66±0.137 for dibenzothiophene and 2,5-dimethyl thiophene respectively. The removal of harmful heavy metals utilizing the Pistia plant and recycling in the wastewater treatment process may therefore be inferred as being highly valued. Additionally, the Co-doped ZnO photocatalysts might improve photocatalytic activity owing to the catalysts' porosity and the hole recombination and electron suppression.
{"title":"GREEN SYNTHESIS AND CHARACTERIZATION OF CODOPED ZnO NANOPARTICLES VIA THE ACCUMULATION OF COBALT ION ONTO PISTIA (Pistia stratiotes L.,) PLANT TISSUE AND ITS PHOTOCATALYTIC ACTIVITY TOWARD ORGANOSULFUR POLLUTANTS","authors":"N. Rani, P. Pavani, Chebolu Naga Sesha Sai Pavan Kumar, Satwinder Singh Marok, S. Tulasi","doi":"10.31788/rjc.2021.1618165","DOIUrl":"https://doi.org/10.31788/rjc.2021.1618165","url":null,"abstract":"Water pollution has recently become a serious global problem and hence researchers were focusing to develop innovative methods for the purification of water and then getting access to purified water by reducing pollution. As a result, the current study concentrated on synthesizing cobalt-doped zinc oxide nanoparticles by accumulating cobalt ions on Pistia (Pistiastratiotes L.) plant tissue and combining them with zinc acetate precursor. Further, the synthesized particles were analyzed for their efficiency in photo-desulphurization of organo sulphur compounds such as Dibenzothiophene and 2,5-dimethyl thiophene. Various characterization studies proved that the nanoparticles were oval in shape and had particle sizes of 8-34 nm and the particles were distributed with less aggregation. The particles have 47 % of zinc element and 21% cobalt with hexagonal (wurtzite) crystalline structure. The synthesized Co-doped ZnO nanoparticles were utilized for the desulfurization of Sulphur containing pollutants such as dibenzothiophene and 2,5-dimethyl thiophene. The results proved that rapid desulfurization was observed during the initial time of the study. The % desulfurization of 14.36±0.136 and 19.63±0.201% was observed within 5 min of the study for dibenzothiophene and 2,5-dimethyl thiophene. Whereas the high % desulfurization was noticed within less time of 25 min wherein the % desulfurization was observed to be 95.61±0.279 and 93.66±0.137 for dibenzothiophene and 2,5-dimethyl thiophene respectively. The removal of harmful heavy metals utilizing the Pistia plant and recycling in the wastewater treatment process may therefore be inferred as being highly valued. Additionally, the Co-doped ZnO photocatalysts might improve photocatalytic activity owing to the catalysts' porosity and the hole recombination and electron suppression.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69405206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1616951
Ruslan, J. Hardi, M. Mirzan, Muliana, M. Ganti
Meti shell contains calcium carbonate which can be calcined into CaO and used as a heterogeneous catalyst in biodiesel synthesis. This study evaluated the ability of CaO catalyst from Meti shell with concentrations of 1, 2, 3, 4, and 5% for the synthesis of biodiesel from Moringa seed oil at various transesterification times (1, 2, 3, and 4 hours). The presence of CaO in the Meti shell was indicated by diffraction at 2θ angles of 32.47o , 37.74o , 54.22o , 64.65o , and 67.67oC. Utilizing CaO 3% and a transesterification reaction time of 3 hours resulted in an Rf value corresponding to the standard biodiesel Rf ranges, i.e. 0.69 and 0.66, respectively. The synthesized biodiesel has the highest methyl oleate content of 59.16% with characteristics that have met Indonesian National Standard (SNI 04-7182-2006), including water content of 0.004%, an acid number of 0.06 mg KOH/g, saponification number 273.6 mgKOH/g, iodine number 78.678 g iodine/100 g, the cloud point is 10oC, the pour point is 21oC, however, the cetane number is still below the minimum number of 51.
{"title":"APPLICATION OF HETEROGENEOUS CATALYST OF Meti SHELLS (Batissa violecea L. von Lamark 1818) IN THE PRODUCTION OF BIODIESEL BASED ON MORINGA SEED OIL","authors":"Ruslan, J. Hardi, M. Mirzan, Muliana, M. Ganti","doi":"10.31788/rjc.2023.1616951","DOIUrl":"https://doi.org/10.31788/rjc.2023.1616951","url":null,"abstract":"Meti shell contains calcium carbonate which can be calcined into CaO and used as a heterogeneous catalyst in biodiesel synthesis. This study evaluated the ability of CaO catalyst from Meti shell with concentrations of 1, 2, 3, 4, and 5% for the synthesis of biodiesel from Moringa seed oil at various transesterification times (1, 2, 3, and 4 hours). The presence of CaO in the Meti shell was indicated by diffraction at 2θ angles of 32.47o , 37.74o , 54.22o , 64.65o , and 67.67oC. Utilizing CaO 3% and a transesterification reaction time of 3 hours resulted in an Rf value corresponding to the standard biodiesel Rf ranges, i.e. 0.69 and 0.66, respectively. The synthesized biodiesel has the highest methyl oleate content of 59.16% with characteristics that have met Indonesian National Standard (SNI 04-7182-2006), including water content of 0.004%, an acid number of 0.06 mg KOH/g, saponification number 273.6 mgKOH/g, iodine number 78.678 g iodine/100 g, the cloud point is 10oC, the pour point is 21oC, however, the cetane number is still below the minimum number of 51.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1617074
M. F. Lubis, P. Hasibuan, V. E. Kaban, R. Astyka
The use of chemotherapy such as cisplatin in treating cancer alone can cause many problems, including side effects and resistance. Therefore, currently, efforts are being made to combine cisplatin with natural ingredients such as ethanol extract from duku leaves. Then extracted using ethanol as a solvent. The secondary metabolites of the extract were identified using LC-MS/MS with mobile phase A (0.1 percent formic acid in water) and phase B (0.1 percent formic acid in acetonitrile). The extract and cisplatin were determined by their IC50 values as the basis for carrying out the combination test using the MTT method. All data obtained were processed with Microsoft Excel and analyzed with SPSS 23. The ethanol extract of duku leaves contains about 15 compounds that cannot be clearly identified because they are not listed in the LC-MS/MS library used. Interestingly, there were 5 compounds that gave a sufficiently large absorption each at a retention time of 1.08; 5.18; 9.45; 9.57; 10.70; and 10.82. Cisplatin has stronger cytotoxic properties than the extract with IC50 values of 3.02±0.05 µg/mL and 28.61±0.13 µg/mL, respectively. The combination of these two substances is synergistic with a combination index <1. the combination of extract and cisplatin at doses of 1.75:0.75 and 1.75:0.375 had very strong synergy with a combination index of 0.01 (p>0.05). However, the mechanism of action of this combination is not yet known clearly, so further research is needed on it.
{"title":"PHYTOCHEMICALS ANALYSIS AND CYTOTOXIC ACTIVITY OF Lansium domesticum Corr EXTRACT-CISPLATIN COMBINATION AGAINST PANC-1 CELL LINE","authors":"M. F. Lubis, P. Hasibuan, V. E. Kaban, R. Astyka","doi":"10.31788/rjc.2023.1617074","DOIUrl":"https://doi.org/10.31788/rjc.2023.1617074","url":null,"abstract":"The use of chemotherapy such as cisplatin in treating cancer alone can cause many problems, including side effects and resistance. Therefore, currently, efforts are being made to combine cisplatin with natural ingredients such as ethanol extract from duku leaves. Then extracted using ethanol as a solvent. The secondary metabolites of the extract were identified using LC-MS/MS with mobile phase A (0.1 percent formic acid in water) and phase B (0.1 percent formic acid in acetonitrile). The extract and cisplatin were determined by their IC50 values as the basis for carrying out the combination test using the MTT method. All data obtained were processed with Microsoft Excel and analyzed with SPSS 23. The ethanol extract of duku leaves contains about 15 compounds that cannot be clearly identified because they are not listed in the LC-MS/MS library used. Interestingly, there were 5 compounds that gave a sufficiently large absorption each at a retention time of 1.08; 5.18; 9.45; 9.57; 10.70; and 10.82. Cisplatin has stronger cytotoxic properties than the extract with IC50 values of 3.02±0.05 µg/mL and 28.61±0.13 µg/mL, respectively. The combination of these two substances is synergistic with a combination index <1. the combination of extract and cisplatin at doses of 1.75:0.75 and 1.75:0.375 had very strong synergy with a combination index of 0.01 (p>0.05). However, the mechanism of action of this combination is not yet known clearly, so further research is needed on it.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69409795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1618129
V. Ragunathan, Meenambiga Setti Sudharsan, Roshini S.R., Gomathy Sundar, Chithra K.
This research scintillates the synthesis of silver nanoparticles from chitosan (C-AgNps) from squid pens as a reducing and stabilizing agent and assesses its antioxidant, antibacterial, and anticancer potentials. The nanoparticles were 240 to 290 nm with excellent stability of +98.2 mV. The C-AgNps possessed an excellent 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity with an IC50 of 6.65 µg/mL. The C-AgNps showed exceptional antibacterial properties against S. aureus, B. subtilis, P. aeruginosa, and E. coli using a good diffusion assay. The C-AgNps also showed outstanding anticancer properties against A375 human skin malignant melanoma. Thus, the C-AgNps could be used as antimicrobial and anticancer agents for novel therapeutics after lead optimization and in-vivo clinical trials.
{"title":"SQUID PENS MEDIATED SILVER NANOPARTICLES SYNTHESIS, ITS CHARACTERISATION, AND BIOLOGICAL ACTIVITIES","authors":"V. Ragunathan, Meenambiga Setti Sudharsan, Roshini S.R., Gomathy Sundar, Chithra K.","doi":"10.31788/rjc.2023.1618129","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618129","url":null,"abstract":"This research scintillates the synthesis of silver nanoparticles from chitosan (C-AgNps) from squid pens as a reducing and stabilizing agent and assesses its antioxidant, antibacterial, and anticancer potentials. The nanoparticles were 240 to 290 nm with excellent stability of +98.2 mV. The C-AgNps possessed an excellent 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity with an IC50 of 6.65 µg/mL. The C-AgNps showed exceptional antibacterial properties against S. aureus, B. subtilis, P. aeruginosa, and E. coli using a good diffusion assay. The C-AgNps also showed outstanding anticancer properties against A375 human skin malignant melanoma. Thus, the C-AgNps could be used as antimicrobial and anticancer agents for novel therapeutics after lead optimization and in-vivo clinical trials.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69410573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1628147a
K. Laavanya, B. Manju, D. A. Shirmila, M. Priya, J. Hemalatha, G. Usha
The recent global COVID-19 pandemic has drawn awareness among the people towards Kabasura Kudineer (KSK) and its healthcare benefits in Tamil Nadu, India. It has been traditionally used for effective management of respiratory ailments such as flu and colds. Nine Phytochemicals were identified through the Gas ChromatographyMass Spectrometry (GCMS) study, from the KSK extract with ethanol. Fourier transforms infrared (FT-IR), FTRAMAN, and UV studies were carried out for spectral investigations on the same KSK extract. The in vitro evaluation reveals the antimicrobial, cytotoxicity, and anticancer activity against human carcinoma (HT29) cells. One of the compounds was utilized for AutoDocking to check the anticancer efficacy of the KSK extract.
{"title":"GC-MS AND OPTICAL CHARACTERIZATION, BIOLOGICAL PROPERTY STUDIES OF ETHANOLIC EXTRACT OF KABASURAKUDINEER AND MOLECULAR DOCKING INVESTIGATION OF (E)-3-PHENYL-1-(2, 2, 4- TRIMETHYLQUINOLIN-1-YL) PROP-2-EN-1-ONE","authors":"K. Laavanya, B. Manju, D. A. Shirmila, M. Priya, J. Hemalatha, G. Usha","doi":"10.31788/rjc.2023.1628147a","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628147a","url":null,"abstract":"The recent global COVID-19 pandemic has drawn awareness among the people towards Kabasura Kudineer (KSK) and its healthcare benefits in Tamil Nadu, India. It has been traditionally used for effective management of respiratory ailments such as flu and colds. Nine Phytochemicals were identified through the Gas ChromatographyMass Spectrometry (GCMS) study, from the KSK extract with ethanol. Fourier transforms infrared (FT-IR), FTRAMAN, and UV studies were carried out for spectral investigations on the same KSK extract. The in vitro evaluation reveals the antimicrobial, cytotoxicity, and anticancer activity against human carcinoma (HT29) cells. One of the compounds was utilized for AutoDocking to check the anticancer efficacy of the KSK extract.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1628174
Shahabaj M. Bagwan, M. Farooqui, M. A. Pathan, Satish M Patil, Mohamad Asif
One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reaction of o-amino phenol and substituted aryl aldehydes by using amla fruit extract at room temperature or under microwave radiation. Amla fruit extract is a biocatalyst associated with low-cost, inexpensive, non-volatile, and environmentally friendly. The prepared catalyst shows many chemical, phytochemical, and anti-oxidant constituents, which are unfavorable to increase the acidic contents of water extract. The noteworthy benefits of this process are simple, easy methodology, an excellent yield of product, minimum time of reaction, ease of separation, easy work, and green catalyst. The prepared compound where characterized by analytical or spectroscopic techniques such as FT-IR (infrared) spectrum, H1-NMR, C13-NMR, and LC-MS (Mass) analysis.
{"title":"GREEN APPROACH FOR THE PREPARATION OF 2-ARYL-1, 3-BENZOXAZOLE DERIVATIVES BY USING Amla Fruit EXTRACT","authors":"Shahabaj M. Bagwan, M. Farooqui, M. A. Pathan, Satish M Patil, Mohamad Asif","doi":"10.31788/rjc.2023.1628174","DOIUrl":"https://doi.org/10.31788/rjc.2023.1628174","url":null,"abstract":"One pot, rapid and green preparation of 2-aryl-1,3-benzoxazole and their derivatives via the reaction of o-amino phenol and substituted aryl aldehydes by using amla fruit extract at room temperature or under microwave radiation. Amla fruit extract is a biocatalyst associated with low-cost, inexpensive, non-volatile, and environmentally friendly. The prepared catalyst shows many chemical, phytochemical, and anti-oxidant constituents, which are unfavorable to increase the acidic contents of water extract. The noteworthy benefits of this process are simple, easy methodology, an excellent yield of product, minimum time of reaction, ease of separation, easy work, and green catalyst. The prepared compound where characterized by analytical or spectroscopic techniques such as FT-IR (infrared) spectrum, H1-NMR, C13-NMR, and LC-MS (Mass) analysis.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1618193
Pravin S. Bodkhe, Sushil K. Pagariya, Prafulla P.Chaudhari
In synthetic chemistry,propane-1,3-diones or β-diketones act as significant intermediates for the synthesis of core heterocycles due to their specific chemoselectivity properties as well as provide convenient building blocks to biologically active substituents. In the present work, a new series of β-diketones namely 1-(5’-Formyl-2’-hydroxy3’-methoxyphenyl)-3-(substitutedphenyl) propane-1,3-diones 4(a-e) have been synthesized from versatile 4- hydroxy-3-methoxybenzaldehyde viz. vanillin and studied their invitro anti-inflammatory and antioxidant potential by performing inhibition of protein denaturation assay and reducing power assay method respectively. All the newly synthesized compounds exhibit notable and satisfactory anti-inflammatory potential as well as potent antioxidant activity due to the presence of vanillin moiety in their molecular structure
{"title":"In-vitro ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF NOVEL 1-SUBSTITUTED-3-SUBSTITUTED PROPANE-1,3-DIONES (β-DIKETONES) DERIVED FROM VANILLIN","authors":"Pravin S. Bodkhe, Sushil K. Pagariya, Prafulla P.Chaudhari","doi":"10.31788/rjc.2023.1618193","DOIUrl":"https://doi.org/10.31788/rjc.2023.1618193","url":null,"abstract":"In synthetic chemistry,propane-1,3-diones or β-diketones act as significant intermediates for the synthesis of core heterocycles due to their specific chemoselectivity properties as well as provide convenient building blocks to biologically active substituents. In the present work, a new series of β-diketones namely 1-(5’-Formyl-2’-hydroxy3’-methoxyphenyl)-3-(substitutedphenyl) propane-1,3-diones 4(a-e) have been synthesized from versatile 4- hydroxy-3-methoxybenzaldehyde viz. vanillin and studied their invitro anti-inflammatory and antioxidant potential by performing inhibition of protein denaturation assay and reducing power assay method respectively. All the newly synthesized compounds exhibit notable and satisfactory anti-inflammatory potential as well as potent antioxidant activity due to the presence of vanillin moiety in their molecular structure","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69411130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.31788/rjc.2023.1638383
H. Nguyen, H. Nguyen, Tuyet-Mai Tran-Thuy, L. Nguyen, H.H. Lam, D. V. Nguyen
Dragon fruit branches are an abundant and underutilized waste released from the annual pruning of dragon fruit. In this study, dragon fruit branches were used for the first time as a raw material for producing magnetic biochar through one-pot pyrolysis. The results showed that zero-valent iron and magnetite particles were generated in the carbon matrix, providing a saturation magnetization of 5.92 emu/g. Due to FeCl3 activation, magnetic biochar possessed a total pore volume of 0.15 cm3 /g and a specific surface area of 203 m2 /g. Subsequently, magnetic biochar was explored as a catalyst for enhanced ozonation of sunset yellow. 95% of sunset yellow (50 ppm) was treated within 80 min at pH 7.0. From the calculation results using pseudo-first-order kinetics, the sunset yellow decolorization constant was improved by 79% by using the magnetic biochar catalyst compared to ozone alone. Overall, dragon fruit branchderived magnetic biochar is a promising material, especially as a green catalyst, because of its magnetic separability and potential catalytic activity for the treatment of sunset yellow by ozone.
{"title":"ONE-POT PREPARATION OF MAGNETIC BIOCHAR FROM DRAGON FRUIT BRANCH FOR CATALYTIC OZONATION OF SUNSET YELLOW","authors":"H. Nguyen, H. Nguyen, Tuyet-Mai Tran-Thuy, L. Nguyen, H.H. Lam, D. V. Nguyen","doi":"10.31788/rjc.2023.1638383","DOIUrl":"https://doi.org/10.31788/rjc.2023.1638383","url":null,"abstract":"Dragon fruit branches are an abundant and underutilized waste released from the annual pruning of dragon fruit. In this study, dragon fruit branches were used for the first time as a raw material for producing magnetic biochar through one-pot pyrolysis. The results showed that zero-valent iron and magnetite particles were generated in the carbon matrix, providing a saturation magnetization of 5.92 emu/g. Due to FeCl3 activation, magnetic biochar possessed a total pore volume of 0.15 cm3 /g and a specific surface area of 203 m2 /g. Subsequently, magnetic biochar was explored as a catalyst for enhanced ozonation of sunset yellow. 95% of sunset yellow (50 ppm) was treated within 80 min at pH 7.0. From the calculation results using pseudo-first-order kinetics, the sunset yellow decolorization constant was improved by 79% by using the magnetic biochar catalyst compared to ozone alone. Overall, dragon fruit branchderived magnetic biochar is a promising material, especially as a green catalyst, because of its magnetic separability and potential catalytic activity for the treatment of sunset yellow by ozone.","PeriodicalId":21063,"journal":{"name":"Rasayan Journal of Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69412204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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