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Review article on Role of Artificial Intelligence in Radiology 人工智能在放射学中的作用综述
Pub Date : 2023-08-05 DOI: 10.52711/0975-4385.2023.00041
Shraddha Jain, Sanket Jain, Sujit Pillai, Rampal Singh Mandloi
Artificial intelligence is gradually changing the landscape of healthcare and biomedical research. Artificial Intelligence is a field of science that pursue the goal of creating intelligent application and machine that can be mimic human cognitive functions, such as learning and problem solving machine learning {NL} and deep learning {DL} are subsets of artificial intelligence{AI}. Life expectancy has been increasing worldwide due to significant improvements in healthcare, and medicine, as well as due to growing consciousness about personal and environmental hygiene. In this paper e discussed about Radiology, Specific trends, Autonomous robotic surgery, Technical challenges in AI developments, Role of AI in last decades, applications of AI and future aspect of AI.
人工智能正在逐渐改变医疗保健和生物医学研究的格局。人工智能是一个科学领域,追求创造智能应用程序和机器的目标,可以模仿人类的认知功能,如学习和解决问题的机器学习{NL}和深度学习{DL}是人工智能{AI}的子集。由于医疗保健和医学的显著改善,以及对个人和环境卫生的意识日益增强,世界范围内的预期寿命一直在增加。在本文中,我们讨论了放射学,特定趋势,自主机器人手术,人工智能发展中的技术挑战,人工智能在过去几十年的作用,人工智能的应用和人工智能的未来方面。
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引用次数: 0
Pharmacognostical studies on the leaves and stems of Hibiscus hispidissimus Griffith 木槿叶和茎的生药学研究
Pub Date : 2023-08-05 DOI: 10.52711/0975-4385.2023.00033
Soorya L S, Indira G, Omanakuttan Reshma
Traditionally medicinal plants have been used for the prevention and treatment of various diseases. Hibiscus hispidissimus Griffith is one of the unexplored medicinal plants, distributed in the Western Ghats of India and also found in China, Thailand, Sri Lanka, etc. Common names include ‘Comfort root’, or ‘Hill hemp bendy’. Vernacular names are Uppanacham in Malayalam and Sathambasthi in Sanskrit. It is used as food and medicine. Tribal healers traditionally use this plant for anthelmintic, antibacterial, antioxidant, anti-inflammatory, antidiabetic, anti-arthritic, diuretic, nephroprotective, and hepatoprotective activities1. The present study is focused on the evaluation of macroscopical, microscopical characters and physicochemical parameters of leaves and stems of Hibiscus hispidissimus Griffith belongs to the family Malvaceae. The result of the study can be used to develop pharmacognostic standards for the drug, which helps in determining the identity and purity of the drug. The microscopical characters and physico chemical parameters are useful in preparing herbal monograph for particular species of medicinal plants.
传统上药用植物被用来预防和治疗各种疾病。Hibiscus hispidissimus Griffith是一种未被开发的药用植物,分布在印度的西高止山脉,在中国、泰国、斯里兰卡等地也有发现。常见的名字包括“舒适根”,或“山麻弯曲”。当地的名字是马拉雅拉姆语的Uppanacham和梵语的Sathambasthi。它被用作食物和药物。部落治疗师传统上使用这种植物来驱虫药、抗菌、抗氧化、抗炎、抗糖尿病、抗关节炎、利尿剂、保护肾脏和保护肝脏。本文对锦葵科木槿(hispidissimus Griffith)叶、茎的宏观、微观性状和理化参数进行了评价。研究结果可用于制定该药物的生药学标准,有助于确定该药物的特性和纯度。其显微特征和理化参数对特定种类药用植物的草药专著的编制具有重要意义。
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引用次数: 0
Brummit, Peristrophe paniculata (Forssk.) – A Common Tropical Medicinal Herb 一种常见的热带草本植物
Pub Date : 2023-08-05 DOI: 10.52711/0975-4385.2023.00039
Mekala K, Jagitha Banu K, Vasundra L, Kanniga V
Peristrophe paniculata is a traditional medicinal plant with a variety of medicinal applications. Its leaf has long been used to treat eye and ear diseases, bacterial infections, and as an antidote to insect stings and bites. It is a Dicotyledonous plant. Herbs that stand upright, with 6-angular, hispid stems. Leaves simple, opposite, ovate, apex acute, base rounded or truncate. Flowers in axillary trichotomous cymes with pedicels up to 2cm long. The phytochemical analysis using hexane, ethyl acetate and hydroalcoholic extracts revealed the presence of carbohydrates in stem, sterols and carbohydrates in leaves, terpenoids, alkaloids, phenols in root respectively in all extracts. An ethanolic extract of P. paniculata inhibited the growth of Escherichia coli (E. coli), Bacillus cereus, and Staphylococcus aureus. The leaf and stem extract significantly reduced the radial growth of Colletotrichum capsicum. Hydroalcoholic extracts of P. paniculata stem part have the highest activity when compared to other extracts such as the standard drug rifampicin. Hexane extract was more active against Escherichia coli (E. coli) than ethyl acetate extract for Klebsiella pneumoniae and hydroalcoholic extract for Salmonella typhi. The cold-water extract is the most active because it completely immobilizes the parasites in the shortest time (35min) compared to the other extracts. P. bicalyculata extracts can induce cytotoxicity and cell death in cancer cells. The extracts were able to target cancer cells more selectively than normal cells. Methanolic leaf extract increased antioxidant capacity and prevented neuroinflammation in experimental animals.
秋葵是一种具有多种药用价值的传统药用植物。它的叶子长期以来被用来治疗眼睛和耳朵疾病,细菌感染,以及作为昆虫叮咬的解毒剂。它是一种双子叶植物。直立的草本,具6角,具硬毛的茎。单叶,对生,卵形,先端锐尖,基部圆形或截形。花腋生三分生聚伞花序,花梗可达2厘米长。用正己烷、乙酸乙酯和水醇提取物进行植物化学分析,发现茎中含有碳水化合物,叶中含有甾醇和碳水化合物,根中含有萜类、生物碱和酚类物质。葡萄球菌的乙醇提取物抑制大肠杆菌、蜡样芽孢杆菌和金黄色葡萄球菌的生长。茎叶提取物显著降低了辣椒的径向生长。与标准药物利福平等其他提取物相比,金银花茎部的水醇提取物具有最高的活性。己烷提取物对大肠杆菌的抑菌活性高于乙酸乙酯提取物对肺炎克雷伯菌的抑菌活性和对伤寒沙门氏菌的抑菌活性。与其他提取物相比,冷水提取物在最短的时间内(35min)完全固定寄生虫,因此活性最高。双柳花提取物可诱导癌细胞的细胞毒性和细胞死亡。这些提取物能够比正常细胞更有选择性地靶向癌细胞。乙醇叶提取物可提高实验动物的抗氧化能力,预防神经炎症。
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引用次数: 0
A Review on Pharmacological activities of Colocasia esculenta 土芋草药理活性研究进展
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00019
Khush Jain, Fariah Rizwani, S. Thakkar
Mother Nature has always given us essential medicinal plants for long decades. Today modern world has started its dependability on medicinal agents obtained from traditionally used plants. Colocasia esculenta is a magnificent source of fiber and starch, which is responsible for number of health benefits, such as for improved blood sugar levels, for better skin care, helps to reduce obesity. Colocasia esculenta also contains a variety of antioxidants and polyphenols. Leaves are caloriedeficient, rich in proteins, micronutrients, dietary fiber and good carbohydrates which enhance the metabolism of our digestive system and it helps to provide healthy weight loss, even they have abundant presence of anti-nutrients such as tannins, oxalates. It consists of high levels of Vit.E, Vit.C, and Vit. B6 also contributes to maintain a better immune system and may eradicate free radicals. All parts of Colocasia esculenta have essential properties including some levels of toxicity which are overcome by cooking and steamed boiling. It has several health benefits like anti-hepatotoxic and hepatoprotective activity, anti-inflammatory activity, neuropharmacological activity, anti-fungal activity and anti-metastatic activity. In India major Colocasia esculenta production occurs in states like Uttar-Pradesh, Kerala, Maharashtra, Tamil Nadu, Himachal-Pradesh, Gujarat, etc. The present review includes detail study of pharmacological activity of plant- Colocasia esculenta [Taro].
大自然母亲几十年来一直给我们提供必需的药用植物。今天,现代世界已经开始依赖从传统使用的植物中获得的药物。土芋草是纤维和淀粉的绝佳来源,对健康有很多好处,比如改善血糖水平,更好地护理皮肤,有助于减少肥胖。土芋草还含有多种抗氧化剂和多酚。叶子缺乏热量,富含蛋白质、微量营养素、膳食纤维和有益的碳水化合物,它们能促进我们消化系统的新陈代谢,有助于健康减肥,甚至它们还含有大量抗营养物质,如单宁酸、草酸盐。它含有高水平的维生素d。E, c,和。B6还有助于维持更好的免疫系统,并可能消除自由基。土芋草的所有部分都具有基本的特性,包括一定程度的毒性,这些毒性可以通过烹饪和蒸煮来克服。它具有多种健康益处,如抗肝毒性和肝保护活性,抗炎活性,神经药理活性,抗真菌活性和抗转移活性。在印度,主要的大白菜生产发生在北方邦、喀拉拉邦、马哈拉施特拉邦、泰米尔纳德邦、喜马偕尔邦、古吉拉特邦等邦。本文对植物芋的药理活性进行了较详细的研究。
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引用次数: 0
A Review on Polyherbal Formulation Used in the Treatment of Gastric Acidity 中药复方治疗胃酸的研究进展
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00027
Prerana Musale, S. D. Mankar
Acidity is a medical condition caused by an excess of acid production. This acid is produced by the stomach glands. Acidity causes symptoms such as stomach ulcers, gastric inflammation, heartburn, and dyspepsia. Acidity is a global issue caused by an imbalance between the acid-secreting mechanisms of the stomach and the proximal intestine. It causes a lot of problems in the lives of many people. An antacid reduces acidity and provides relief. This review article discusses different polyherbal formulations (PHF) used to treat gastric acidity. Due to its role in medicine and therapy, PHF has been used all over the world. The current study discusses a variety of commercial and non-commercial polyherbal formulations used worldwide to treat gastric acidity, as well as their therapeutic potential, clinical and preclinical outcomes, and safety and efficacy. This review will make it easier to learn everything about the previous scientific research as well as the crucial details about the antacid properties of polyherbal preparations, which will encourage young researchers to conduct additional studies in the future to protect people from gastric acidity. Natural herbs and their extracts are used in herbal treatment as an alternative to conventional medication to treat various conditions. It has been demonstrated that several medications contain medicinal components useful for treating ulcers or stomach acidity. The subject of the current work is the claim that a polyherbal formulation can be utilised as an alternative to currently available antacid formulations on the market. As a result, those plants that can reduce stomach acid are chosen, and a formulation is created.
酸度是由过量的酸产生引起的一种医学状况。这种酸是由胃腺产生的。酸度会引起胃溃疡、胃炎、胃灼热和消化不良等症状。胃酸是一个全球性的问题,是由胃和近端肠道分泌酸机制的不平衡引起的。它给许多人的生活带来了很多问题。抗酸剂能降低酸度,缓解疼痛。本文综述了治疗胃酸的多种中药制剂。由于其在医学和治疗中的作用,PHF已在世界各地使用。目前的研究讨论了世界范围内用于治疗胃酸的各种商业和非商业多草药配方,以及它们的治疗潜力、临床和临床前结果、安全性和有效性。这篇综述将使我们更容易了解以前的科学研究以及关于多草药制剂抗酸特性的关键细节,这将鼓励年轻的研究人员在未来进行更多的研究,以保护人们免受胃酸的侵害。天然草药及其提取物在草药治疗中被用作常规药物的替代品来治疗各种疾病。已经证明,几种药物含有治疗溃疡或胃酸的有效成分。当前工作的主题是声称多草药制剂可以用作市场上目前可用的抗酸制剂的替代品。因此,选择那些可以减少胃酸的植物,并创建一个配方。
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引用次数: 0
Review on Herbal Excipients 草药赋形剂综述
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00018
Nida Mulla Mam, Sanjay Bias, Mahajan Manasi
The fact that herbal or natural excipients are non-toxic, inexpensive, and readily available gives them a significant advantage over their synthetic analogues. The pharmaceutical industries are becoming more inclined toward using these herbal excipients, which are mainly polymers of natural origin, in formulation development as awareness of these excipients grows. The plant-derived gums and mucilages from natural sources, such as tragacanth, carrageenan, thaumatin, lard, storax, and agar, meet many of the specifications for pharmaceutical excipients. These can be chosen over their synthetic counterparts for formulation development since they are more stable and come with less regulatory concerns. They are a powerful and affordable method of administering active pharmacological ingredients because they can be easily changed to match the demands of each individual patient. In view of their biocompatibility and capacity to provide additional nutrition to the established dosage form, natural excipients have the potential to be utilised as diluents, binder, disintegrants, and lubricants in a variety of formulations.
事实上,草药或天然赋形剂是无毒的,便宜的,并且容易获得,这使它们比它们的合成类似物具有显著的优势。随着对这些赋形剂认识的提高,制药工业越来越倾向于在配方开发中使用这些主要是天然聚合物的草药赋形剂。来自天然来源的植物胶和粘液,如黄花胶、卡拉胶、牛油、猪油、storax和琼脂,满足许多药用辅料的规格。在配方开发中,可以选择这些物质,而不是它们的合成物,因为它们更稳定,监管问题也更少。它们是一种有效且负担得起的管理活性药理成分的方法,因为它们可以很容易地改变以匹配每个患者的需求。鉴于其生物相容性和为既定剂型提供额外营养的能力,天然赋形剂具有在各种配方中用作稀释剂、粘合剂、崩解剂和润滑剂的潜力。
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引用次数: 0
A Review on: Phytoconstituents, Traditional and Medicinal uses of Taraxacum offinale (Dandelion) 蒲公英(Taraxacum offinale)植物成分、传统及药用研究进展
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00021
Umair Akhtar, Anjali M. Wankhade, Jugalkishor V. Vyas, Vivek V. Paithankar
Since 5000 BC, medicinal plants have been used in India as part of the Ayurvedic medical system. Medical professionals frequently use herbal remedies. Taraxacum officinale, commonly called dandelion, is a perennial plant belonging to the family Asteraceae. It is also known as wet-a-bed, lion’s tooth, priest’s crown, blowball, milk gowan, wild endive, white endive, puffball, and Irish daisy. Long and upright flowering stalks with a single terminal inflorescence are present. It has numerous medicinal properties due to phytochemicals found in the plant's flower, leaf, stem, and roots. Sesquiterpenes found in dandelion root extracts. The root also includes a number of phenolic substances. The two sesquiterpenes taraxinic acid b-Dglucopyranoside and 11, 13-dihydrotaraxinic acid b-Dglucopyranoside An extract of combined dandelion leaves and flowers has been found to contain a number of flavonoid glycosides. Dandelion roots and leaves have historically been used to treat liver issues. Additionally, Native Americans used dandelion to treat heartburn, swelling, skin issues, kidney disease, and upset stomach. Research has been conducted to back up the descriptions of taraxacum that have been made so far. Up to doses of 10 g/kg (per oral) and 4 g/kg (intraperitoneal) of dried drug -per kilogramme body weight- in rats and mice, ethanolic extracts demonstrated very low toxicity.
自公元前5000年以来,药用植物已经在印度被用作阿育吠陀医疗系统的一部分。医疗专业人员经常使用草药治疗。蒲公英,俗称蒲公英,是一种多年生植物,属于菊科。它也被称为wet-a-bed,狮子的牙齿,牧师的皇冠,blowball, milk gowan,野生菊苣,白菊苣,puffball和爱尔兰雏菊。具有单顶生花序的长而直立的花柄。由于在植物的花、叶、茎和根中发现的植物化学物质,它具有许多药用特性。蒲公英根提取物中的倍半萜素。根中还含有许多酚类物质。两种倍半萜蒲公英酸b-Dglucopyranoside和11,13 -二氢蒲公英酸b-Dglucopyranoside是蒲公英叶和花的提取物,已被发现含有许多类黄酮苷。蒲公英的根和叶历来被用来治疗肝脏问题。此外,美洲原住民用蒲公英治疗胃灼热、肿胀、皮肤问题、肾脏疾病和胃部不适。已经进行了研究来支持迄今为止对蒲公英的描述。在大鼠和小鼠中,高达每公斤体重10克/公斤(每次口服)和4克/公斤(腹腔注射)的干燥药物剂量,乙醇提取物显示出非常低的毒性。
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引用次数: 0
A Review on Argemone maxicana Linn.
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00023
P. Morey, A. Wankhade, J. Vyas, V. Paithankar
Argemone mexicana Linn belonging to family papaveraceae is widely distributed plant in tropical and sub-tropical regions of the world. The Papaveraceae, also known as the poppy family, is a family of flowering plants with 44 genera and about 760 species that is significant from an ethnopharmacological perspective. In India, It can be found alongside roads, in fields, and near bodies of water. It has roots, flowers, and leaves. It also goes by the name "Mexican Poppy." The current paper provides a review of Argemone mexicana Linn. thorough chemistry and pharmacology. This plant is one of the most important species in traditional systems of medicine. Despite the fact that alkaloids are mostly prevalent, the plant is a source of a wide variety of chemical elements. Some plant parts have hazardous consequences in addition to pharmacological efficacies. In this article, phytochemical, morphological, microscopical, and pharmacological investigations are reviewed. Current knowledge about this plant's chemistry and pharmacology may be useful for directing researchers who want to conduct additional research in these areas.
墨西哥银花属木瓜科,是一种广泛分布于全球热带和亚热带地区的植物。罂粟科,也被称为罂粟科,是开花植物的一个科,有44属,约760种,从民族药理学的角度来看是重要的。在印度,可以在路边、田野和水体附近找到它。它有根、花和叶。它也被称为"墨西哥罂粟"本文综述了墨西哥凤尾草的研究进展。全面的化学和药理学。这种植物是传统医学体系中最重要的物种之一。尽管生物碱普遍存在,但这种植物是多种化学元素的来源。一些植物部分除了具有药理功效外,还具有有害的后果。在本文中,植物化学,形态学,显微和药理学研究综述。目前对这种植物的化学和药理学的了解可能有助于指导想要在这些领域进行进一步研究的研究人员。
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引用次数: 0
Formulation and Evaluation of Herbal Hair Serum in Treatment of Various Hair- Related Problems 草本毛发血清治疗各种毛发相关问题的配方及评价
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00016
Gayatri M. Penkar, Maithilee R. Salkar, Prachi S. Chavan, Maitrey S. Ambade, Sanchit A. Parab, Manasvi M. Sawant, Vijay A. Japgap
In this expeditious world, cosmetics are in great demand. Cosmeceuticals in Pharmaceutical industry is booming day-by-day. Cosmetics are used on daily basis. Cosmetics are intended for skincare, hair care, nails and for teeth as well. Also, to take the note, toothpastes, hair oils, hair dyes are classified into the cosmetics that is been used by every individual on everyday basis. The synthetic or chemical products have side effects and adverse effects of when used, thus now people have high approach towards organic, natural and herbal formulations that show no or minimum side effects. Generally herbal preparations are known for its “No side effect” property. Various problems are experienced by the people such as hair fall, split ends, dandruff, increased sebum production, hair thinning, premature hair greying etc. Thus, people are looking for ways to increase hair development, their prevention and care. A hair serum helps to lock the moisture and keep the scalp hydrated and healthy. Trigonella foenum graecum (Fenugreek) is a popular homemade remedy for hair growth and also improves hair density. Flaxseed is beneficial in treatment of dandruff and boosts hair growth. Citrus sinensis is rich in anti-oxidants that are very effective in treatment of spilt ends. Ginger has high content of gingerol which improves the blood circulation and boosts hair growth. Castor oil, Vitamin E, Hibiscus is also useful in treating dry and damaged hair, provides hydration to the scalp. Thus, preparation of the herbal formulation using natural products will help in treatment of various hair diseases.
在这个瞬息万变的世界里,化妆品需求量很大。医药工业中的药妆品日益繁荣。化妆品每天都在使用。化妆品是用来护肤、护发、指甲和牙齿的。此外,牙膏、发油、染发剂被归类为每个人每天都在使用的化妆品。合成或化学产品在使用时有副作用和不良反应,因此现在人们对有机,天然和草药配方有很高的态度,这些配方没有或最小的副作用。一般来说,草药制剂以其“无副作用”的特性而闻名。人们会遇到各种各样的问题,比如头发脱落、分叉、头皮屑、皮脂分泌增加、头发稀疏、头发过早变白等。因此,人们正在寻找促进头发发育、预防和护理的方法。护发精华有助于锁住水分,保持头皮水分和健康。葫芦巴(葫芦巴)是一种受欢迎的促进头发生长的自制药物,也能改善头发密度。亚麻籽有利于治疗头皮屑,促进头发生长。柑桔含有丰富的抗氧化剂,对处理果皮外溢非常有效。生姜含有高含量的姜辣素,可以改善血液循环,促进头发生长。蓖麻油,维生素E,芙蓉花对治疗干燥和受损的头发也很有用,为头皮提供水分。因此,使用天然产品制备草药制剂将有助于治疗各种头发疾病。
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引用次数: 0
Pharmacognostic and Phytochemical Screening of Lantana camara Linn. roots collected from Karnataka, India 山楂的生药学和植物化学筛选。从印度卡纳塔克邦采集的根
Pub Date : 2023-05-20 DOI: 10.52711/0975-4385.2023.00015
A. Ali, M. Malipatil
Lantana camara is an evergreen plant found throughout the world. Traditionally it has been used in the treatment of various ailments and has been supported by scientific investigation. Phytoconstituents present in almost all parts of this plant have been reported in various literature. In this work, we attempt to establish parameters to scientifically identify the root part of Lantana camara, with morphological details and high-resolution photomicrographs to identify microscopical characters and key elements, microscopic studies have revealed the presence of a wavy intact rhizodermal layer, characteristic xylem and phloem, distinctive vessels with perforation etc., phytochemical investigations, such as extractive values in different solvents, detect and report the presence or absence of alkaloids, flavonoids, phenols, saponins, tannins, terpenoids, anthraquinone glycosides and steroids from extracts with different solvents.
山楂是一种常绿植物,遍布世界各地。传统上,它被用于治疗各种疾病,并得到了科学研究的支持。在各种文献中都报道了这种植物几乎所有部分的植物成分。在这项工作中,我们试图建立参数来科学地鉴定山药的根部分,通过形态学细节和高分辨率显微照片来鉴定显微特征和关键元素,显微镜研究发现了波浪状完整的根皮层,特征木质部和韧皮部,独特的血管穿孔等,植物化学研究,如在不同溶剂中的提取值,检测并报告不同溶剂萃取物中生物碱、黄酮类、酚类、皂苷、单宁、萜类、蒽醌苷和类固醇的存在或缺失。
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引用次数: 1
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Research Journal of Pharmacognosy and Phytochemistry
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