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Tinospora cordifolia a Medicinal plant with many roles: A Review 一种具有多种用途的药用植物:综述
Pub Date : 2023-03-17 DOI: 10.52711/0975-4385.2023.00013
Rushikesh Said, S. Jadhav, S. C. Kamble
Ancient time of human civilization, medicinal plants are utilized by humans for its therapeutic and medicinal property. Nature is great source of medicinal plants from thousands of year and so many drugs are now isolated and extracted from medicinal plants. Traditional medicine is affordable and easily accessible source for many treatment in the primary healthcare system to treat many poor communities in India and different countries. Currently the interest is to seek out Nutraceuticals from medicinal plants to avoid adverse effect of synthetic drugs and for economic purpose. India is great resource of medicinal herbs. Tinospora cordifolia is a extensively used shrub in Ayurveda systems of medicine all over India. Almost all of its part have medicinal property and used in traditional systems of medicine but Leaves, stem and roots are the most important parts which are used medicinally. Tinospora cordifolia is a versatile resource of medicinal plant used for many purpose in life. It belongs to family Menispermaceae. Recently the discovery and new research of active components from the Tinospora cordifolia and its biological function for disease controlling property has led to active interest in the plant across the globe. The scope of these review in future is to exploit biochemical and signaling pathways affect which is isolated from Tinospora and from these we can prepare new and effective formulation in disease eradication. The review paper will highlight the various ethnobotanical and traditional uses. It also focused on various pharmacological, phytochemical and clinical reports on Tinospora cardifolia.
在人类文明的远古时代,药用植物就因其治疗和药用的特性而被人类所利用。自然界是数千年来药用植物的重要来源,现在从药用植物中分离和提取了许多药物。传统医学是印度和其他国家许多贫困社区的初级卫生保健系统中许多治疗的负担得起和容易获得的来源。从药用植物中寻找营养药品,以避免合成药物的不良反应,并达到经济目的是目前的兴趣。印度是巨大的草药资源。Tinospora cordifolia是印度阿育吠陀医学系统中广泛使用的灌木。它的几乎所有部分都具有药用价值,在传统的医学系统中使用,但叶子、茎和根是最重要的药用部分。堇青花是一种用途广泛的药用植物资源。它属于menispermacae科。近年来,堇青花有效成分的发现和新研究及其防治病害的生物学功能引起了全球对该植物的积极关注。今后的研究方向是利用从Tinospora中分离得到的生物化学和信号通路,制备新的有效的根治制剂。这篇评论文章将强调各种民族植物学和传统用途。它还集中在各种药理学,植物化学和临床报告的Tinospora cardifolia。
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引用次数: 0
Formulation and Evaluation of Antimicrobial Herbal Ointment containing Colocasia esculenta 含土芋草抗菌药膏的配方及评价
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00048
Mohini R. Shelke, Pankaj Sonawane, Ganesh R. Bharskar, S. D. Mankar
Herbal medicine refers to the use of any plant's seeds, berries, roots, leaves, bark, or flowers for medicinal purposes. The objective of the study was to formulate and evaluate the antimicrobial herbal ointment from ethanolic extracts of leaves of Colocasia esculenta. The ointment base was created, and the ointment was made by using the levigation process to incorporate the extract into the base. It was assessed for physicochemical criteria such as colour, odour, pH, spreadability, extrudability, consistency, diffusion studies, solubility, and washability once the formulation was completed. The formulation was further tested for stability at various temperatures, revealing no differences in irritancy, spreadability.
草药指的是任何植物的种子、浆果、根、叶、树皮或花的药用用途。本研究的目的是制备并评价土芋叶乙醇提取物的抗菌药膏。软膏的基础是创建的,软膏是通过使用levigation过程将提取物纳入基础。在配方完成后,对其进行了物理化学标准评估,如颜色,气味,pH值,铺展性,可压缩性,一致性,扩散研究,溶解度和可水洗性。进一步测试了该配方在不同温度下的稳定性,显示在刺激性和涂抹性方面没有差异。
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引用次数: 0
Evaluation of White fleshed sweet potato (Ipomoea batatas (L) Lam) Genotypes in different agro-ecologies of Southwest Ethiopia 埃塞俄比亚西南部不同农业生态环境下白肉甘薯基因型的评价
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00042
Tewodros Mulualem, Getachew Etanna, Neim Semman
A multi-locational evaluation trial of six white fleshed sweet potato genotypes was conducted in four locations during 2019 and 2020 cropping seasons. The objective of this study was to determine the magnitude of genotype by environment interaction (GEI) for storage root yield and yield-related traits of sweet potato genotypes and to assess the adaptability and stability of sweet potato genotypes in different production environments in southwest Ethiopia. Six genotypes were evaluated across eight diverse environments using a randomized complete block design (RCBD) with three replications. Data were collected on yield and yield components in all tested locations. The results showed highly significant difference (p<0.01) for genotype effect, environmental affect and environment by genotype interaction (GEI) for all the traits studied. The analysis also revealed that the magnitude of the mean square of environment was higher than those of the genotype and GEI for all the traits studied indicating the uniqueness of the tested environments. The genotypes Hawassa-83, and Tula were identified both high mean root yield and high stability, closest to the ideal genotype for root performance and consistency of performance across environments. This study provides valuable information that could be utilized in a breeding program to ameliorate genotypes of sweet potato in Ethiopia.
在2019年和2020年种植季,在4个地点对6个白肉甘薯基因型进行了多地点评价试验。本研究的目的是通过环境相互作用(GEI)确定甘薯基因型对贮藏、根产量和产量相关性状的影响程度,并评估甘薯基因型在埃塞俄比亚西南部不同生产环境下的适应性和稳定性。采用随机完全区组设计(RCBD)进行3次重复,在8种不同环境中评估6种基因型。收集了所有测试地点的产量和产量组成部分的数据。结果表明,各性状的基因型效应、环境效应和环境基因型互作(GEI)差异极显著(p<0.01)。分析还发现,环境均方的大小均大于基因型和GEI的大小,表明所测环境具有独特性。基因型Hawassa-83和Tula均具有较高的平均根产量和高稳定性,最接近于根系性能和跨环境性能一致性的理想基因型。本研究为埃塞俄比亚甘薯基因型改良育种提供了有价值的信息。
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引用次数: 0
Spectroscopic Analysis and ADME prediction of Phytochemicals in Methanolic Leaves Extract of Avicennia marina 海棠叶甲醇提取物中植物化学物质的光谱分析及ADME预测
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00041
Sachin Vanpure, Nishant Nandkhile, R. Bhondwe, Suresh Palve
Phytochemicals are biologically active compounds found in plants. Phytochemicals of medicinal plant can cure various diseases thus phytochemical screening of plants is necessary for the discovery and devlopment of therapeutic agents. In present study. The FTIR spectrum of crude extract confirmed the presence of alkanes, carboxylic acid, alcohol, aromatics and esters. The HPLC analysis of methanolic extract shows 11 peaks at 254nm, it may be phenolic and alcoholic compounds. The plant extract was scanned by using UV-VIS spectrophotometer ranging from 200-700nm and characteristic peaks were detected with different absorption respectively. The ADME study particularly focuses on important properties like lipophilicity, water solubility, pharmacokinetic, drug likeness, medicinal chemistry and this study carried out by using insilico ADME tool called Swiss ADME.
植物化学物质是在植物中发现的具有生物活性的化合物。药用植物的植物化学物质可以治疗多种疾病,因此植物的植物化学筛选是发现和开发治疗剂的必要条件。在目前的研究中。粗提物的FTIR光谱证实了其存在烷烃、羧酸、醇、芳烃和酯类。甲醇提取物在254nm处有11个峰,可能为酚类和醇类化合物。采用紫外-可见分光光度计对提取液进行扫描,在200 ~ 700nm范围内分别检测不同吸收度的特征峰。ADME研究特别关注亲脂性、水溶性、药代动力学、药物相似性、药物化学等重要性质,本研究使用名为Swiss ADME的insilico ADME工具进行。
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引用次数: 1
Conspectus on Tephrosia purpurea: An Introduction 紫荆概述:导论
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00049
Roman Kumar Aneshwari, A. Vyas, Vishal Jain
Tephrosia purpurea, which is also termed as sharpunkha in Ayurveda, is a wild herb of family Fabaceae. Geographically it is found at an altitude between 400 m to 1300 m in countries like India, Sri Lanka, China and Australia. Natural habitat of Tephrosia purpurea is in dry, sandy or rocky soil. It is seen growing along the roadside and places where waste are dump. Phytochemical investigations on Tephrosia purpurea shows the presence of constituents such as carbohydrates, protein, amino acid, tannins, saponins, terpenes, flavanones, rotenoids, chalcones, isoflavones, glycosides, alkaloids, flavanols, and sterols. It has also shown the presence of lupeol, lanceolatins A and B semiglabrin, rutin, sitosterol and pongamole. Flavonoids such as (+)-tephrosin A and B, (+)-tephrosone, isoflavone, 7, 4' dihydroxy-3', 5'-dimethoxyflavone and a chalcone, (+)-tephropurpurin were present in the whole plant and that was isolated from it. Different parts of the whole plant has shown variety of pharmacological actions ranging from anti-inflammatory to antitumor along with activities such as antiulcer , hepatoprotective, antioxidant, antimicrobial and antiallergic. Moreover it has also shown insect repellent activity. This review has summarized the literature related to phytochemical and pharmacological study of Tephrosia purpurea (L.) Pers. till August 2012. Tephrosia purpurea is regarded as folk medicine due to several therapeutic properties like anti-daibetic, anticancer, antipyretic. It also has pharmacological importance due to the potent chemical constituent.
Tephrosia purpurea,在印度吠陀语中也被称为sharpunkha,是一种豆科野生草本植物。在地理上,它在印度、斯里兰卡、中国和澳大利亚等国家的海拔400米至1300米之间。毛茛的自然栖息地在干燥、沙质或岩石土壤中。它生长在路边和垃圾倾倒的地方。对紫毛豆的植物化学研究表明其含有碳水化合物、蛋白质、氨基酸、单宁、皂苷、萜烯、黄烷酮、类鱼素、查尔酮、异黄酮、苷类、生物碱、黄烷醇和甾醇等成分。它还显示出了芦皮醇、松皮素A和B、半乳糖素、芦丁、谷甾醇和蓬加莫里的存在。黄酮类化合物(+)-tephrosin A和B、(+)-tephrosin、异黄酮、7,4 '二羟基-3'、5'-二甲氧基黄酮和查尔酮、(+)-tephropurpurin等均从该植物中分离得到。整个植物的不同部位显示出多种药理作用,从抗炎到抗肿瘤,并具有抗溃疡、保肝、抗氧化、抗菌和抗过敏等活性。此外,它还具有驱虫活性。本文对紫荆植物化学和药理研究的相关文献进行了综述。珀耳斯。至2012年8月。紫荆具有抗糖尿病、抗癌、解热等功效,被认为是民间药材。由于其强大的化学成分,它也具有药理意义。
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引用次数: 0
Antiobesity Activity of Zingiber officinale 生姜的抗肥胖作用
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00044
Sagar B. Patil, Snehal D. Kothavale
Obesity is a metabolic disorder that is linked to a wide spectrum of chronic diseases, increasing comorbidity and mortality significantly. The rhizome of Zingiber officinale Roscoe (Zingiberaceae) is widely used in Indian traditional medicine to cure a variety of ailments. The current study looked at the antiviral, radioprotective, anti-inflammatory, anticancer, and antioxidant properties of Z officinale, with an emphasis on Ayurvedic prescriptions. Metabolic syndromes (MetSs), which include diabetes, dyslipidemia, and cardiovascular disease, have emerged as a prevalent health concern in both industrialised and developing nations in recent years.
肥胖是一种代谢紊乱,与多种慢性疾病有关,显著增加了合并症和死亡率。姜的根茎(姜科)在印度传统医学中被广泛用于治疗各种疾病。目前的研究着眼于Z officinale的抗病毒、防辐射、抗炎、抗癌和抗氧化特性,重点是阿育吠陀处方。代谢综合征包括糖尿病、血脂异常和心血管疾病,近年来已成为工业化国家和发展中国家普遍关注的健康问题。
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引用次数: 0
Response of Weed Management on Growth, Yield and Yield Attributes of Kharif maize (Zea mays L.) 杂草管理对丰收玉米生长、产量及产量属性的响应
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00047
Gavande V. S., Mundphane D. S., Jadhav K. T.
The present investigation entitled “Weed management in kharif maize (Zeamays L)” was carried out during kharif 2019 at College Farm, College of Agriculture, Badnapur, Dist.- Jalna. Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhnai Maharashtra (India). Randomized Block design used for study which comprises ten treatments. Among treatments, weed free treatment attributed more number of leaves, maximum plant height, dry matter production and leaf area per plant followed by treatment of topramezone 33.6% SC @ 25.2g a.i.ha-1 + atrazine 50% WP @ 250g a.i.ha-1. Poor growth attributes were recorded in weedy check. Significantly maximum values of yield attributes were recorded in treatment of topramezone 33.6 % SC @ 25.2g a.i.ha-1 + atrazine 50% WP @ 250 (g) a.i. ha-1 followed by treatment of tembotrione 42% SC @ 105g a.i.ha-1 + atrazine 50% WP @ 250 g a,i. ha-1. Minimum values of yield attributes were attributed in weedy check. Treatment of topramezone + atrazine @ 25.2 + 250g a.i ha-1 as PoE (T6) found effective in limiting weed growth and recorded lower weed index, weed dry matter with higher weed control efficiency followed by tembotrione + atrazine @ 105 + 250(g) a.i.ha-1 as PoE (T7) at all growth stages of crop. Lower uptake of nitrogen, phosphorous and potassium by weeds were recorded in treatment of topramezone + atrazine @ 25.2+ 250g a.i.ha-1 as PoE followed by tembotrione + atrazine @ 105 +250g a.i. ha-1 as PoE. The benefit cost ratio was highest (2.94) with application of topramezone + atrazine @ 25.2 + 250g a.i ha-1 followed by tembotrione + atrazine @ 105 + 250g a.i. ha-1 as PoE (2.81) whereas weedy check recorded significantly lower B:C ratio (1.50) over other treatments.
本调查题为“收割玉米(Zeamays L)的杂草管理”,于2019年收割期间在贾尔纳邦巴德那普尔农业学院的学院农场进行。Vasantrao Naik Marathwada Krishi Vidyapeeth, Parbhnai Maharashtra(印度)随机区组设计用于研究,包括10个处理。无杂草处理对单株叶片数、最高株高、干物质产量和叶面积的贡献最大,其次是施用33.6% SC @ 25.2g a.i.ha-1 + 50%阿特拉津@ 250g a.i.ha-1。在杂草检查中记录了不良的生长属性。产率最高的是topamezone处理33.6% SC @ 25.2g a.i.ha-1 +阿特拉津50% WP @ 250 (g) a.i.ha-1,其次是tembotrione处理42% SC @ 105g a.i.ha-1 +阿特拉津50% WP @ 250 g a,i。农业的。在杂草检查中对产量属性的最小值进行了赋值。topramezone + atrazine @ 25.2 + 250g a.i.ha-1作为PoE (T6)处理对杂草生长有一定的限制作用,杂草指数较低,杂草干物质控制效率较高,其次是tembotrione + atrazine @ 105 + 250(g) a.i.ha-1作为PoE (T7)。以托拉米宗+阿特拉津(25.2+ 250g a.i.ha-1)为PoE处理,杂草对氮、磷、钾的吸收量较低,其次是替博曲酮+阿特拉津(105 +250g a.i.ha-1)为PoE。使用topramezone +阿特拉津(25.2 + 250g a.i. ha-1)的效益成本比最高(2.94),其次是tembotrione +阿特拉津(105 + 250g a.i. ha-1)作为PoE(2.81),而weeedy check记录的B:C比明显低于其他处理(1.50)。
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引用次数: 0
Study of Metals and Element characterization of Andrographis paniculata plant of Khordha region, Odisha 奥里萨邦科尔达地区穿心莲植物金属及元素特征研究
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00045
Shreetam Parida, D. Sahoo, Pratima Kumari Mishra
This study represents characterization of different metals present in Andrographis paniculata (a medicinal herb). The plant samples were collected from urban and rural areas of Khordha district, Odisha, India. The solid powdered samples from different parts of the plants were analyzed using various chemical and physical characterization techniques and all the data provides a clear description about the metal and mineral contents in the plant parts qualitatively and quantitatively as well. X-ray Fluorescence study was done to know the presence of different metals (including other elements) qualitatively. The collected samples were taken for ashing, followed by acid digestion and analyzed by AAS and ICP-OES (Pb, Cr, Mn, Co, Zn, Cu, Cr, V, Na, Ca, and Mg), FES (Ca, Na, and K) respectively. It has been found that leaves of the plants of both the regions are rich in Fe, Mg, Ca, K, Mn etc. In addition to these metals Pb, Cr, Co, Pd, and V also exists, but in low concentrations which have negligible impact on the medicinal characteristics of the plant (but are toxic). Structural characterization (FESEM) is under process.
本文研究了穿心莲(一种中药)中不同金属的特征。植物样本采集自印度奥里萨邦科尔达区的城市和农村地区。利用各种化学和物理表征技术对植物不同部位的固体粉末样品进行了分析,所有数据都提供了对植物各部位金属和矿物含量的定性和定量的清晰描述。x射线荧光研究定性地了解不同金属(包括其他元素)的存在。采用原子吸收光谱法、ICP-OES法(Pb、Cr、Mn、Co、Zn、Cu、Cr、V、Na、Ca、Mg)和FES法(Ca、Na、K)对样品进行灰化、酸消解分析。研究发现,这两个地区的植物叶片都富含铁、镁、钙、钾、锰等元素。除了这些金属外,还存在Pb、Cr、Co、Pd和V,但浓度较低,对植物的药用特性影响微不足道(但有毒)。结构表征(FESEM)正在进行中。
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引用次数: 0
Astilbe rivularis: Phytoconstituent and Pharmacological activity 江蓠:植物成分及药理活性
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00040
Sushilta Pradhan, Bibhas Pandit, Safal Sharma, J. Priya Mohanty
Astilbe rivularis is a medically rich species belonging to the family Saxifragaceae. An herb that can grow up to 2.5 meters tall and has nearly 20 species in the genus, it is commonly and traditionally used as medicine in Nepal and the Eastern Himalayan regions of Darjeeling and Sikkim. Astilbe rivularis have been medically used in the treatment of swelling, spasm, gastric ulcer, diarrhea, and bleeding. Due to the presence of phytoconstituents like alkaloids, flavonoids, terpenoids, and coumarin, medical activity can be triggered and below a comprehensive review of its chemical constituents, ethnomedical use and pharmacological profit as a medical plant has been given. Separation of these compounds leads to the affirmation of particular biological activities like anti-inflammation, anti-bacterial, anti-oxidant, and anti-peptic ulcer as that its potential use can be better evaluated.
芦笋是一种具有丰富药用价值的沙盆科植物。这种草药可以长到2.5米高,有近20种,在尼泊尔和大吉岭和锡金的东喜马拉雅地区,它通常被传统地用作药物。黄曲霉在医学上被用于治疗肿胀、痉挛、胃溃疡、腹泻和出血。由于生物碱、黄酮类化合物、萜类化合物和香豆素等植物成分的存在,可以引发医学活性,下面对其化学成分、民族医学用途和作为药用植物的药理价值进行了全面的综述。这些化合物的分离使其具有抗炎、抗菌、抗氧化、抗消化性溃疡等特殊的生物活性,从而更好地评价其潜在的用途。
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引用次数: 0
Phytochemical Study and Anxiolytic activity of Hibiscus cannabinus leaves 大麻木槿叶的植物化学研究及抗焦虑活性
Pub Date : 2022-11-12 DOI: 10.52711/0975-4385.2022.00046
Chitrarekha A Jadhav, Ravindra S. Jadhav, Sunaina R Vikhe
As a result of high experience from the past generations, today, all over the world’s cultures have an extensive knowledge of herbal medicine. Traditional medicines have great importance in our culture. Hibiscus cannabinus plant has therapeutic used in traditional system of medicines in India. Hibiscus cannabinus L. (Malvaceae) is an herbaceous annual plant with high potential. This plant contains different phytoconstituents such as Alkaloids, Carbohydrates, steroids, tannins, phenols, proteins, saponins. This information described and discussed the chemical constituents, pharmacognostic and phytochemical study of Hibiscus cannabinus leaf.
由于过去几代人的丰富经验,今天,世界各地的文化都有广泛的草药知识。传统医学在我们的文化中占有重要地位。在印度,大麻植物木槿在传统医药体系中具有治疗作用。木槿(malvacae)是一种极具潜力的一年生草本植物。这种植物含有不同的植物成分,如生物碱、碳水化合物、类固醇、单宁、酚类、蛋白质、皂苷。本文介绍并讨论了木槿叶的化学成分、生药学和植物化学研究。
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引用次数: 0
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Research Journal of Pharmacognosy and Phytochemistry
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