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Colloquium: Inclusions, boundaries, and disorder in scalar active matter 学术讨论会:标量活性物质中的夹杂物、边界和无序状态
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-09-30 DOI: 10.1103/revmodphys.96.031003
Omer Granek, Yariv Kafri, Mehran Kardar, Sunghan Ro, Julien Tailleur, Alexandre Solon
Active systems are driven out of equilibrium by exchanging energy and momentum with their environment. This endows them with anomalous mechanical properties that are reviewed in this Colloquium. The case of dry scalar active matter is considered, which encompasses systems whose large-scale behaviors are entirely captured by their density—a scalar field. Arguably the simplest of active-matter systems, they have attracted considerable attention due to their unusual properties when put in contact with boundaries, inclusions, tracers, or disordered potentials. Indeed, studies of the mechanical pressure of active fluids and of the dynamics of passive tracers have shown that active systems impact their environment in nontrivial ways, for example, by propelling and rotating anisotropic inclusions. Conversely, the long-range density and current modulations induced by localized obstacles show how the environment can have a far-reaching impact on active fluids. This is best exemplified by the propensity of bulk and boundary disorder to destroy bulk phase separation in active matter, thereby showing active systems to be much more sensitive to their surroundings than passive ones. This Colloquium aims to provide a unifying perspective on the rich interplay between active systems and their environments.
有源系统通过与环境交换能量和动量而打破平衡。这赋予了它们反常的机械特性,本学术讨论会将对这些特性进行评述。干标量活性物质的情况被考虑在内,它包括其大尺度行为完全由其密度--标量场--所捕获的系统。它们可以说是最简单的活性物质系统,但由于在与边界、夹杂物、示踪剂或无序电势接触时具有不同寻常的特性,因此吸引了相当多的关注。事实上,对活性流体的机械压力和被动示踪剂的动力学研究表明,活性系统会以非同寻常的方式影响其环境,例如推动各向异性夹杂物旋转。相反,局部障碍物引起的长程密度和电流调制显示了环境如何对活性流体产生深远影响。最能体现这一点的是,块体和边界紊乱会破坏活性物质中的块体相分离,从而表明活性系统对周围环境比被动系统更加敏感。本次研讨会旨在提供一个统一的视角,探讨活性系统与其环境之间丰富的相互作用。
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引用次数: 0
FLASH: New intersection of physics, chemistry, biology, and cancer medicine FLASH:物理学、化学、生物学和癌症医学的新交叉点
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-09-19 DOI: 10.1103/revmodphys.96.035002
Marie-Catherine Vozenin, Billy W. Loo, Jr., Sami Tantawi, Peter G. Maxim, Douglas R. Spitz, Claude Bailat, Charles L. Limoli
Ultrahigh dose rate, FLASH radiotherapy has emerged as one of the most promising innovations over the past decade in the field of radiation oncology, with the potential to eradicate radiation resistant primary tumors and improve the therapeutic outcome for cancer patients. FLASH is based on delivering radiation doses at ultrahigh dose rates (UHDR; >40Gy/s), more than 1000 times faster than irradiation at conventional dose rates (CONV). The experimental evidence demonstrating the differential effect of dose rate modulation on tumors and normal tissue is reviewed. Preclinical data consistently show that the antitumor efficacy of cytotoxic doses is not dependent on dose rate, but in normal tissues UHDR significantly reduces normal tissue toxicities compared to CONV, as observed in vivo. These observations define the FLASH effect. The FLASH effect has been reported to occur when using single or hypofractionated dose regimens in several experimental animal models (mice, rat, zebrafish, pig, and cats) and in multiple organs (lung, skin, gut, and brain) by numerous groups worldwide. Note that the FLASH effect has been demonstrated with electron, photon, and hadron (proton and heavier ion) beams. The current status and future technological development are reviewed, with an emphasis on critical beam parameters, future beam modalities, and prerequisites for safe clinical translation in terms of dosimetry, radioprotection, and treatment planning systems. Mechanistic investigations at the physicochemical and biological levels are presented, as are strategies to support and initiate clinical translation. This comprehensive review provides multidisciplinary radiation scientists with a road map of the technological, physical, chemical, biological, and clinical considerations that have made FLASH topical. These considerations are presented with a realistic and practical backdrop of the limitations and challenges that lie ahead.
超高剂量率 FLASH 放射疗法是过去十年来放射肿瘤学领域最有前途的创新技术之一,有望根除耐放射的原发性肿瘤,改善癌症患者的治疗效果。FLASH以超高剂量率(UHDR; >40Gy/s)照射剂量为基础,比常规剂量率(CONV)照射速度快1000多倍。本文回顾了证明剂量率调制对肿瘤和正常组织产生不同影响的实验证据。临床前数据一致表明,细胞毒性剂量的抗肿瘤效果并不依赖于剂量率,但在正常组织中,超高剂量率辐照比常规剂量率辐照显著降低了正常组织的毒性,正如在体内观察到的那样。这些观察结果定义了 FLASH效应。据报道,全球许多研究小组在多个实验动物模型(小鼠、大鼠、斑马鱼、猪和猫)和多个器官(肺、皮肤、肠道和大脑)中使用单剂量或低分剂量方案时,都出现了 FLASH 效应。请注意,FLASH 效应已在电子、光子和强子(质子和重离子)束中得到证实。本文回顾了目前的状况和未来的技术发展,重点是关键的射束参数、未来的射束模式,以及在剂量测定、放射防护和治疗计划系统方面实现安全临床转化的先决条件。此外,还介绍了物理化学和生物学层面的机理研究,以及支持和启动临床转化的策略。这篇全面的综述为多学科辐射科学家提供了一份技术、物理、化学、生物和临床考虑因素的路线图,这些考虑因素使 FLASH 成为热门话题。在介绍这些考虑因素的同时,还以现实和实用为背景,介绍了未来的局限性和挑战。
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引用次数: 0
Nobel Lecture: The route to attosecond pulses 诺贝尔演讲:阿秒脉冲之路
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-08-28 DOI: 10.1103/revmodphys.96.030503
Anne L’Huillier
DOI:https://doi.org/10.1103/RevModPhys.96.030503
DOI:https://doi.org/10.1103/RevModPhys.96.030503
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引用次数: 0
Nobel Lecture: Sub-atomic motions 诺贝尔演讲亚原子运动
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-08-28 DOI: 10.1103/revmodphys.96.030502
Ferenc Krausz
The written version of my lecture is a personal reflection on decades of research on electron-light interactions, culminating in their control and observation in real time at the turn of the millennium. Electrons and light attracted my attention when attending the lectures of György Marx on quantum mechanics and Károly Simonyi on electrodynamics during the 1980s in Budapest. This interest was solidified by my mentor, Arnold Schmidt, and deepened by Paul Corkum, during the 1990s in Vienna. They have influenced my path most profoundly. It has been a tremendous privilege to stand on the shoulders of scientists, including many Nobel laureates, who made seminal contributions to our understanding of electrons and light, when walking the path to exploring sub-atomic motions. To eventually exploit them for addressing grand challenges. To the benefit of humankind.
我的演讲稿是对数十年来电子-光相互作用研究的个人反思,最终在千年之交实现了对电子-光相互作用的实时控制和观测。20 世纪 80 年代,我在布达佩斯聆听捷尔吉-马克思(György Marx)关于量子力学和卡洛里-西蒙尼(Károly Simonyi)关于电动力学的讲座时,电子和光引起了我的注意。20 世纪 90 年代在维也纳,我的导师阿诺德-施密特(Arnold Schmidt)和保罗-科库姆(Paul Corkum)加深了我的兴趣。他们对我的人生道路影响至深。在探索亚原子运动的道路上,能够站在包括许多诺贝尔奖获得者在内的科学家的肩膀上,他们为我们理解电子和光做出了开创性的贡献,我深感荣幸。最终利用它们来应对巨大的挑战。造福人类。
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引用次数: 0
Nobel Lecture: Genesis and applications of attosecond pulse trains 诺贝尔讲座:阿秒脉冲串的起源与应用
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-08-28 DOI: 10.1103/revmodphys.96.030501
Pierre Agostini
DOI:https://doi.org/10.1103/RevModPhys.96.030501
DOI:https://doi.org/10.1103/RevModPhys.96.030501
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引用次数: 0
Colloquium: Eigenvector continuation and projection-based emulators 学术讨论会:特征向量延续和基于投影的仿真器
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-08-14 DOI: 10.1103/revmodphys.96.031002
Thomas Duguet, Andreas Ekström, Richard J. Furnstahl, Sebastian König, Dean Lee
Eigenvector continuation is a computational method for parametric eigenvalue problems that uses subspace projection with a basis derived from eigenvector snapshots from different parameter sets. It is part of a broader class of subspace-projection techniques called reduced-basis methods. In this Colloquium, the development, theory, and applications of eigenvector continuation and projection-based emulators are presented. The basic concepts are introduced, the underlying theory and convergence properties are discussed, and recent applications for quantum systems and future prospects are presented.
特征向量延续是参数特征值问题的一种计算方法,它使用从不同参数集的特征向量快照中提取的基础进行子空间投影。它是更广泛的子空间投影技术的一部分,被称为还原基础方法。本次研讨会将介绍特征向量延续和基于投影的仿真器的发展、理论和应用。介绍了基本概念,讨论了基础理论和收敛特性,并介绍了量子系统的最新应用和未来前景。
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引用次数: 0
Ultimate Rayleigh-Bénard turbulence 终极瑞利-贝纳德湍流
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-08-06 DOI: 10.1103/revmodphys.96.035001
Detlef Lohse, Olga Shishkina
Thermally driven turbulent flows are omnipresent in nature and technology. A good understanding of the physical principles governing such flows is key for numerous problems in oceanography, climatology, geophysics, and astrophysics for problems involving energy conversion, heating and cooling of buildings and rooms, and process technology. In the physics community, the most popular system to study wall-bounded thermally driven turbulence has been Rayleigh-Bénard flow, i.e., the flow in a box heated from below and cooled from above. The dimensionless control parameters are the Rayleigh number Ra (the dimensionless heating strength), the Prandtl number Pr (the ratio of kinematic viscosity to thermal diffusivity), and the aspect ratio Γ of the container. The key response parameters are the Nusselt number Nu (the dimensionless heat flux from the bottom to the top) and the Reynolds number Re (the dimensionless strength of the turbulent flow). While there is good agreement and understanding of the dependences Nu(Ra,Pr,Γ) up to Ra1011 (the “classical regime”), for even larger Ra in the so-called ultimate regime of Rayleigh-Bénard convection the experimental results and their interpretations are more diverse. The transition of the flow to this ultimate regime, which is characterized by strongly enhanced heat transfer, is due to the transition of laminar-type flow in the boundary layers to turbulent-type flow. Understanding this transition is of the utmost importance for extrapolating the heat transfer to large or strongly thermally driven systems. Here the theoretical results on this transition to the ultimate regime are reviewed and an attempt is made to reconcile the various experimental and numerical results. The transition toward the ultimate regime is interpreted as a non-normal–nonlinear and thus subcritical transition. Experimental and numerical strategies are suggested that can help to further illuminate the transition to the ultimate regime and the ultimate regime itself, for which a modified model for the scaling laws in its various subregimes is proposed. Similar transitions in related wall-bounded turbulent flows such as turbulent convection with centrifugal buoyancy and Taylor-Couette turbulence are also discussed.
热驱动湍流在自然界和技术领域无处不在。对于海洋学、气候学、地球物理学和天体物理学中涉及能源转换、建筑物和房间的加热和冷却以及工艺技术的众多问题来说,很好地理解支配这类流动的物理原理是关键所在。在物理学界,研究壁面热驱动湍流最常用的系统是瑞利-贝纳德流,即在一个从下往上加热和从上往下冷却的盒子中的流动。无量纲控制参数为雷利数 Ra(无量纲加热强度)、普朗特数 Pr(运动粘度与热扩散率之比)和容器的长宽比 Γ。关键的响应参数是努塞尔特数 Nu(从底部到顶部的无量纲热流量)和雷诺数 Re(湍流的无量纲强度)。虽然在 Ra∼1011 ("经典制度")范围内,Nu(Ra,Pr,Γ) 的相关性有很好的一致性和理解,但在所谓雷利-贝纳德对流的终极制度中,对于更大的 Ra,实验结果及其解释则更加多样化。流动过渡到这一终极对流状态的特点是热传递强烈增强,这是由于边界层中的层流型流动过渡到了湍流型流动。了解这种过渡对于推断大型或强热驱动系统的传热至关重要。这里回顾了向极限状态过渡的理论结果,并试图协调各种实验和数值结果。向极限状态的过渡被解释为非正态非线性过渡,因此是次临界过渡。提出的实验和数值策略有助于进一步阐明向终极制度和终极制度本身的过渡,并为此提出了一个关于其各种子制度中缩放规律的修正模型。此外,还讨论了相关壁界湍流中的类似过渡,如带离心浮力的湍流对流和泰勒-库埃特湍流。
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引用次数: 0
Colloquium: Quantum batteries 学术讨论会:量子电池
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-07-09 DOI: 10.1103/revmodphys.96.031001
Francesco Campaioli, Stefano Gherardini, James Q. Quach, Marco Polini, Gian Marcello Andolina
Recent years have witnessed an explosion of interest in quantum devices for the production, storage, and transfer of energy. This Colloquium concentrates on the field of quantum energy storage by reviewing recent theoretical and experimental progress in quantum batteries. Provided first is a theoretical background discussing the advantages that quantum batteries offer with respect to their classical analogs. The existing quantum many-body battery models are then reviewed and a thorough discussion of important issues related to their “open nature” is presented. The Colloquium concludes with a discussion of promising experimental implementations, preliminary results available in the literature, and perspectives.
近年来,人们对用于生产、存储和传输能量的量子设备的兴趣激增。本次研讨会通过回顾量子电池的最新理论和实验进展,集中讨论量子能量存储领域。首先是理论背景,讨论量子电池与其经典类似物相比所具有的优势。然后回顾了现有的量子多体电池模型,并对与其 "开放性 "相关的重要问题进行了深入讨论。研讨会最后讨论了有前景的实验实施、文献中的初步结果和展望。
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引用次数: 0
Catalysis in quantum information theory 量子信息论中的催化作用
IF 44.1 1区 物理与天体物理 Q1 PHYSICS, MULTIDISCIPLINARY Pub Date : 2024-06-27 DOI: 10.1103/revmodphys.96.025005
Patryk Lipka-Bartosik, Henrik Wilming, Nelly H. Y. Ng
Catalysts open up new reaction pathways that can speed up chemical reactions while not consuming the catalyst. A similar phenomenon has been discovered in quantum information science, where physical transformations become possible by utilizing a quantum degree of freedom that returns to its initial state at the end of the process. In this review, a comprehensive overview of the concept of catalysis in quantum information science is presented and its applications in various physical contexts are discussed.
催化剂开辟了新的反应途径,在不消耗催化剂的情况下加快了化学反应的速度。量子信息科学中也发现了类似的现象,即利用量子自由度,在过程结束时返回其初始状态,从而使物理转换成为可能。本综述全面概述了量子信息科学中的催化概念,并讨论了它在各种物理环境中的应用。
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引用次数: 0
Neutrinos from dense environments: Flavor mechanisms, theoretical approaches, observations, and new directions 来自高密度环境的中微子:味道机制、理论方法、观测和新方向
IF 44.1 1区 物理与天体物理 Q1 Physics and Astronomy Pub Date : 2024-06-24 DOI: 10.1103/revmodphys.96.025004
M. Cristina Volpe
Neutrino masses and mixings produce vacuum oscillations, an established quantum mechanical phenomenon. In matter, the Mikheev-Smirnov-Wolfenstein effect, due to neutrino interactions with the background particles, triggers resonant flavor modification. In dense environments, such as core-collapse supernovae and compact mergers, sizable neutrino-neutrino interactions, shock waves, and turbulence impact the neutrino flavor content under a variety of phenomena. Theoretical approaches of neutrino propagation range from the mean-field approximation to the full quantum kinetic equations. Interesting connections have been uncovered between weakly interacting dense neutrino gases and other many-body systems and domains, from condensed matter and nuclear physics to quantum computing. Besides the intrinsic theoretical interest, establishing how neutrinos change flavor contributes to answering the long-standing open questions of how massive stars explode and of the r-process sites. It is also important for future observations of core-collapse supernova neutrinos and of the diffuse supernova neutrino background that should be discovered in the foreseeable future.
中微子的质量和混合会产生真空振荡,这是一种公认的量子力学现象。在物质中,由于中微子与背景粒子的相互作用,米赫耶夫-斯米尔诺夫-沃尔芬斯坦效应引发了共振频率的改变。在高密度环境中,如核坍缩超新星和紧凑合并,中微子与中微子之间相当大的相互作用、冲击波和湍流会在各种现象下影响中微子的味道含量。中微子传播的理论方法从平均场近似到完整的量子动力学方程不等。弱相互作用致密中微子气体与其他多体系统和领域(从凝聚态和核物理到量子计算)之间的有趣联系已经被发现。除了内在的理论兴趣之外,确定中微子如何改变味道也有助于回答长期以来关于大质量恒星如何爆炸以及r过程场所的悬而未决的问题。这对未来观测核心坍缩超新星中微子和在可预见的未来发现的弥散超新星中微子背景也很重要。
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引用次数: 0
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