Pub Date : 2023-10-12DOI: 10.1103/revmodphys.95.045001
Mira L. Pöhlker, Christopher Pöhlker, Ovid O. Krüger, Jan-David Förster, Thomas Berkemeier, Wolfgang Elbert, Janine Fröhlich-Nowoisky, Ulrich Pöschl, Gholamhossein Bagheri, Eberhard Bodenschatz, J. Alex Huffman, Simone Scheithauer, Eugene Mikhailov
Knowing the physicochemical properties of exhaled droplets and aerosol particles is a prerequisite for a detailed mechanistic understanding and effective prevention of the airborne transmission of infectious human diseases. This review provides a critical consideration and synthesis of scientific knowledge on the number concentrations, size distributions, composition, mixing state, and related properties of respiratory particles emitted upon breathing, speaking, singing, coughing, and sneezing. A parametrization of respiratory particle size distributions is derived and presented based on five log-normal modes related to different origins in the respiratory tract, which can be used to trace and localize the sources of infectious particles. This approach may support the medical treatment as well as the risk assessment for aerosol and droplet transmission of infectious diseases. It was applied to analyze which respiratory activities may drive the spread of specific pathogens, such as Mycobacterium tuberculosis, influenza viruses, and severe acute respiratory syndrome coronaviruses 2 (SARS-CoV-2). The results confirm the high relevance of vocalization for the transmission of SARS-CoV-2, as well as the usefulness of physical distancing, face masks, room ventilation, and air filtration as preventative measures against coronavirus disease 2019 and other airborne infectious diseases.
{"title":"Respiratory aerosols and droplets in the transmission of infectious diseases","authors":"Mira L. Pöhlker, Christopher Pöhlker, Ovid O. Krüger, Jan-David Förster, Thomas Berkemeier, Wolfgang Elbert, Janine Fröhlich-Nowoisky, Ulrich Pöschl, Gholamhossein Bagheri, Eberhard Bodenschatz, J. Alex Huffman, Simone Scheithauer, Eugene Mikhailov","doi":"10.1103/revmodphys.95.045001","DOIUrl":"https://doi.org/10.1103/revmodphys.95.045001","url":null,"abstract":"Knowing the physicochemical properties of exhaled droplets and aerosol particles is a prerequisite for a detailed mechanistic understanding and effective prevention of the airborne transmission of infectious human diseases. This review provides a critical consideration and synthesis of scientific knowledge on the number concentrations, size distributions, composition, mixing state, and related properties of respiratory particles emitted upon breathing, speaking, singing, coughing, and sneezing. A parametrization of respiratory particle size distributions is derived and presented based on five log-normal modes related to different origins in the respiratory tract, which can be used to trace and localize the sources of infectious particles. This approach may support the medical treatment as well as the risk assessment for aerosol and droplet transmission of infectious diseases. It was applied to analyze which respiratory activities may drive the spread of specific pathogens, such as <i>Mycobacterium tuberculosis</i>, influenza viruses, and severe acute respiratory syndrome coronaviruses 2 (SARS-CoV-2). The results confirm the high relevance of vocalization for the transmission of SARS-CoV-2, as well as the usefulness of physical distancing, face masks, room ventilation, and air filtration as preventative measures against coronavirus disease 2019 and other airborne infectious diseases.","PeriodicalId":21172,"journal":{"name":"Reviews of Modern Physics","volume":"7 5","pages":""},"PeriodicalIF":44.1,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50165194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-28DOI: 10.1103/revmodphys.95.035006
Walter Kutschera, A. J. Timothy Jull, Michael Paul, Anton Wallner
Accelerator mass spectrometry (AMS) was born in the late 1970s, when it was realized at nuclear physics laboratories that the accelerator systems can be used as a sensitive mass spectrometer to measure ultralow traces of long-lived radioisotopes. It soon became possible to measure radioisotope-to-stable-isotope ratios in the range from to by counting the radioisotope ions “atom by atom” and comparing the count rate with ion currents of stable isotopes ( singly charged ions/s). It turned out that electrostatic tandem accelerators are best suited for this, and there are now worldwide about 160 AMS facilities based on this principle. This review presents the history, technological developments, and research areas of AMS through the 45 yr since its discovery. Many different fields are touched by AMS measurements, including archaeology, astrophysics, atmospheric science, biology, climatology, cosmic-ray physics, environmental physics, forensic science, glaciology, geophormology, hydrology, ice core research, meteoritics, nuclear physics, oceanography, and particle physics. Since it is virtually impossible to discuss all fields in detail in this review, only specific fields with recent advances are highlighted in detail. For the others, an effort is made to provide relevant references for in-depth studies of the respective fields.
{"title":"Atom counting with accelerator mass spectroscopy","authors":"Walter Kutschera, A. J. Timothy Jull, Michael Paul, Anton Wallner","doi":"10.1103/revmodphys.95.035006","DOIUrl":"https://doi.org/10.1103/revmodphys.95.035006","url":null,"abstract":"Accelerator mass spectrometry (AMS) was born in the late 1970s, when it was realized at nuclear physics laboratories that the accelerator systems can be used as a sensitive mass spectrometer to measure ultralow traces of long-lived radioisotopes. It soon became possible to measure radioisotope-to-stable-isotope ratios in the range from <math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mrow><msup><mn>10</mn><mrow><mo>−</mo><mn>1</mn><mn>2</mn></mrow></msup></mrow></math> to <math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mrow><msup><mn>10</mn><mrow><mo>−</mo><mn>1</mn><mn>6</mn></mrow></msup></mrow></math> by counting the radioisotope ions “atom by atom” and comparing the count rate with ion currents of stable isotopes (<math display=\"inline\" xmlns=\"http://www.w3.org/1998/Math/MathML\"><mrow><mn>1.6</mn><mtext> </mtext><mtext> </mtext><mi mathvariant=\"normal\">μ</mi><mi mathvariant=\"normal\">A</mi><mo>=</mo><mn>1</mn><mo>×</mo><msup><mrow><mn>10</mn></mrow><mrow><mn>1</mn><mn>3</mn></mrow></msup></mrow></math> singly charged ions/s). It turned out that electrostatic tandem accelerators are best suited for this, and there are now worldwide about 160 AMS facilities based on this principle. This review presents the history, technological developments, and research areas of AMS through the 45 yr since its discovery. Many different fields are touched by AMS measurements, including archaeology, astrophysics, atmospheric science, biology, climatology, cosmic-ray physics, environmental physics, forensic science, glaciology, geophormology, hydrology, ice core research, meteoritics, nuclear physics, oceanography, and particle physics. Since it is virtually impossible to discuss all fields in detail in this review, only specific fields with recent advances are highlighted in detail. For the others, an effort is made to provide relevant references for in-depth studies of the respective fields.","PeriodicalId":21172,"journal":{"name":"Reviews of Modern Physics","volume":"53 24","pages":""},"PeriodicalIF":44.1,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50166620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-27DOI: 10.1103/revmodphys.95.025005
O. Hurricane, P. Patel, R. Betti, D. Froula, S. Regan, S. Slutz, M. Gomez, M. A. Sweeney
{"title":"Physics principles of inertial confinement fusion and U.S. program overview","authors":"O. Hurricane, P. Patel, R. Betti, D. Froula, S. Regan, S. Slutz, M. Gomez, M. A. Sweeney","doi":"10.1103/revmodphys.95.025005","DOIUrl":"https://doi.org/10.1103/revmodphys.95.025005","url":null,"abstract":"","PeriodicalId":21172,"journal":{"name":"Reviews of Modern Physics","volume":" ","pages":""},"PeriodicalIF":44.1,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45678297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-15DOI: 10.1103/RevModPhys.95.031001
M. Zaletel, M. Lukin, C. Monroe, C. Nayak, F. Wilczek, N. Yao
The spontaneous breaking of time translation symmetry has led to the discovery of a new phase of matter - the discrete time crystal. Discrete time crystals exhibit rigid subharmonic oscillations, which result from a combination of many-body interactions, collective synchronization, and ergodicity breaking. This Colloquium reviews recent theoretical and experimental advances in the study of quantum and classical discrete time crystals. We focus on the breaking of ergodicity as the key to discrete time crystals and the delaying of ergodicity as the source of numerous phenomena that share many of the properties of discrete time crystals, including the AC Josephson effect, coupled map lattices, and Faraday waves. Theoretically, there exists a diverse array of strategies to stabilize time crystalline order in both closed and open systems, ranging from localization and prethermalization to dissipation and error correction. Experimentally, many-body quantum simulators provide a natural platform for investigating signatures of time crystalline order; recent work utilizing trapped ions, solid-state spin systems, and superconducting qubits will be reviewed. Finally, this Colloquium concludes by describing outstanding challenges in the field and a vision for new directions on both the experimental and theoretical fronts.
{"title":"Colloquium\u0000: Quantum and classical discrete time crystals","authors":"M. Zaletel, M. Lukin, C. Monroe, C. Nayak, F. Wilczek, N. Yao","doi":"10.1103/RevModPhys.95.031001","DOIUrl":"https://doi.org/10.1103/RevModPhys.95.031001","url":null,"abstract":"The spontaneous breaking of time translation symmetry has led to the discovery of a new phase of matter - the discrete time crystal. Discrete time crystals exhibit rigid subharmonic oscillations, which result from a combination of many-body interactions, collective synchronization, and ergodicity breaking. This Colloquium reviews recent theoretical and experimental advances in the study of quantum and classical discrete time crystals. We focus on the breaking of ergodicity as the key to discrete time crystals and the delaying of ergodicity as the source of numerous phenomena that share many of the properties of discrete time crystals, including the AC Josephson effect, coupled map lattices, and Faraday waves. Theoretically, there exists a diverse array of strategies to stabilize time crystalline order in both closed and open systems, ranging from localization and prethermalization to dissipation and error correction. Experimentally, many-body quantum simulators provide a natural platform for investigating signatures of time crystalline order; recent work utilizing trapped ions, solid-state spin systems, and superconducting qubits will be reviewed. Finally, this Colloquium concludes by describing outstanding challenges in the field and a vision for new directions on both the experimental and theoretical fronts.","PeriodicalId":21172,"journal":{"name":"Reviews of Modern Physics","volume":" ","pages":""},"PeriodicalIF":44.1,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42662129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}