首页 > 最新文献

Revista de Ciencia y Tecnología最新文献

英文 中文
Learnings in the professional initiation of graduates from the Teacher Training Careers at the FCEQyN - UNaM - At Secondary Schools 在FCEQyN - UNaM -中学教师培训职业生涯毕业生的专业入门学习
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.001
Mónica Alicia Oudin
The research had as its object of study the "Learnings in the professional initiation of graduates of the FCEQyN-UNaM - At Secondary Schools". The objectives were: To know and understand the significances that graduates have about their workplace as a field of professional learning. To describe the resources, modalities and processes that enable the learning processes at the moment of initiation into professional life in secondary schools; to detect and analyze the place of graduates learning in school and the meaning they give to their own action; and to provide theoretical underpinnings and referential elements to broaden the conception of professional teacher training. The methodology was framed within the qualitative logic, from an interpretative-critical approach. The actors' perspective was considered, taking into account what they expect, how they are received, what they feel and what they believe they learn. We sought to deepen what is behind these situations and learning.The research had to look at the current institutional context where the graduates work. As research techniques, workshops with the graduates and in-depth interviews with registration were favored.
本研究的研究对象为“福建师范大学中专毕业生的专业入门学习”。目标是:了解和理解毕业生对其工作场所作为专业学习领域的重要性。描述在中学开始进入职业生活的那一刻,使学习过程成为可能的资源、模式和过程;发现和分析毕业生在学校学习的位置和他们给自己的行动的意义;并为拓宽教师专业培训的概念提供理论依据和参考要素。方法论是在定性逻辑框架内,从解释-批判的方法。考虑了演员的观点,考虑了他们的期望,他们如何被接受,他们的感受以及他们认为自己学到了什么。我们试图加深这些情况和学习背后的原因。这项研究必须着眼于毕业生工作的当前制度背景。作为研究方法,与毕业生的研讨会和注册的深度访谈受到青睐。
{"title":"Learnings in the professional initiation of graduates from the Teacher Training Careers at the FCEQyN - UNaM - At Secondary Schools","authors":"Mónica Alicia Oudin","doi":"10.36995/j.recyt.2022.37.001","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.001","url":null,"abstract":"The research had as its object of study the \"Learnings in the professional initiation of graduates of the FCEQyN-UNaM - At Secondary Schools\". The objectives were: To know and understand the significances that graduates have about their workplace as a field of professional learning. To describe the resources, modalities and processes that enable the learning processes at the moment of initiation into professional life in secondary schools; to detect and analyze the place of graduates learning in school and the meaning they give to their own action; and to provide theoretical underpinnings and referential elements to broaden the conception of professional teacher training. \u0000The methodology was framed within the qualitative logic, from an interpretative-critical approach. The actors' perspective was considered, taking into account what they expect, how they are received, what they feel and what they believe they learn. We sought to deepen what is behind these situations and learning.\u0000The research had to look at the current institutional context where the graduates work. As research techniques, workshops with the graduates and in-depth interviews with registration were favored.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"415 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76474454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymeric composite coatings with graphene and graphene oxide for the civil construction – A review 民用建筑用石墨烯和氧化石墨烯聚合物复合涂料综述
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.006
Rithyeli Lage Souza, Igor Martins Coura, S. Silva
Steel is one of the most used materials in civil construction and, although it exhibits a very satisfactory performance in terms of mechanical properties, it has the disadvantage of susceptibility to tribochemical mechanisms. Corrosion of steel of reinforced concrete structures (Standard NBR 7480 - CA50) can affect its structural integrity, decreasing its resistance to external stresses, affecting the service life and, therefore, the durability of the structure. The most common pathological manifestations in steel structures are mainly caused by the accumulation of moisture, deficient drainage of rainwater, and lack of protection against the corrosion process. Polymeric coatings with Graphene and Graphene oxide (GO) can be seen as a solution to these corrosion problems in carbon steel due to its chemical stability combined with its high properties such as the degree of hydrophobicity, impermeability to many types of salts and gases, in addition to its good conductivity, GO additions allow to obtain a coating with greater durability. This work aims to discuss the influence of GO on the improvement of anti-corrosion coatings on carbon steel. The literature points out that the introduction of GO concentration in the mass ratios of 0.1 to 5% w/w in coatings has the potential to improve the tribochemical properties of the coating on carbon steel. In this article, a bibliographical review was carried out about the use of GO applied to carbon steel in civil construction, its main methods of processing composites of a polymeric matrix reinforced with graphene oxide, as well as to check if there is an improvement in the main properties of that material.
钢是民用建筑中使用最多的材料之一,尽管它在机械性能方面表现出非常令人满意的性能,但它的缺点是易受摩擦化学机制的影响。钢筋混凝土结构钢材(标准NBR 7480 - CA50)的腐蚀会影响其结构的完整性,降低其抗外部应力的能力,影响结构的使用寿命,从而影响结构的耐久性。钢结构中最常见的病理表现主要是由于湿气积聚,雨水排水不足,缺乏对腐蚀过程的保护。石墨烯和氧化石墨烯(GO)的聚合物涂层可以被视为解决碳钢腐蚀问题的解决方案,因为它具有化学稳定性和高性能,如疏水性程度,对许多类型的盐和气体的不渗透性,除了具有良好的导电性外,添加GO可以获得具有更高耐久性的涂层。本文旨在探讨氧化石墨烯对改善碳钢防腐涂层的影响。文献指出,在涂层中引入质量比为0.1 ~ 5% w/w的氧化石墨烯浓度,有可能改善碳钢涂层的摩擦化学性能。在本文中,对氧化石墨烯在民用建筑中应用于碳钢的应用进行了文献综述,其主要方法是加工氧化石墨烯增强聚合物基体复合材料,并检查该材料的主要性能是否有改善。
{"title":"Polymeric composite coatings with graphene and graphene oxide for the civil construction – A review","authors":"Rithyeli Lage Souza, Igor Martins Coura, S. Silva","doi":"10.36995/j.recyt.2022.37.006","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.006","url":null,"abstract":"Steel is one of the most used materials in civil construction and, although it exhibits a very satisfactory performance in terms of mechanical properties, it has the disadvantage of susceptibility to tribochemical mechanisms. Corrosion of steel of reinforced concrete structures (Standard NBR 7480 - CA50) can affect its structural integrity, decreasing its resistance to external stresses, affecting the service life and, therefore, the durability of the structure. The most common pathological manifestations in steel structures are mainly caused by the accumulation of moisture, deficient drainage of rainwater, and lack of protection against the corrosion process. Polymeric coatings with Graphene and Graphene oxide (GO) can be seen as a solution to these corrosion problems in carbon steel due to its chemical stability combined with its high properties such as the degree of hydrophobicity, impermeability to many types of salts and gases, in addition to its good conductivity, GO additions allow to obtain a coating with greater durability. This work aims to discuss the influence of GO on the improvement of anti-corrosion coatings on carbon steel. The literature points out that the introduction of GO concentration in the mass ratios of 0.1 to 5% w/w in coatings has the potential to improve the tribochemical properties of the coating on carbon steel. In this article, a bibliographical review was carried out about the use of GO applied to carbon steel in civil construction, its main methods of processing composites of a polymeric matrix reinforced with graphene oxide, as well as to check if there is an improvement in the main properties of that material.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75026843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of quality control system of the in vitro production of sugarcane 甘蔗离体生产质量控制体系的完善
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.007
Miguel Suárez Castellá, C. Galian, J. Cabral, Rafael Gómez Kosky, Aydiloide Bernal Villegas, Irenaldo Delgado Mora, Dunia Nuñez Jaramillo, Midiala Bermúdez Calimano, Edel Toledo Rodríguez
The Sugarcane Biofactory at the Villa Clara Center Sugarcane Research Territorial Station plays a vital role in sugarcane production, since it provides seeds of high genetic and phytosanitary quality obtained by biotechnological methods. For this, strict control of the processes is required, derived from the requirements of environmental and personal asepsis established by in vitro propagation technology. However, the current quality control system presents a group of limitations and insufficiencies related to their information that were not related to each other, which makes it impossible to determine with certainty and speed the causes of production losses. Additionally, it is not complemented with operating procedures of the processes that are carried out in production. This problem was solved with the design and implementation of a group of improvements in the quality control system and operating procedures. These are validated by the results in a group of indicators: 100% customer satisfaction is achieved for the productions delivered, 3.8% lost in vitro production, 95% viable in vitro establishment, 99.3% of culture media produced with quality, 93% survival of in vitro plants during acclimatization, among others. All of this led to 100% compliance with the production plan.
维拉克拉拉中心甘蔗研究领土站的甘蔗生物工厂在甘蔗生产中起着至关重要的作用,因为它提供了通过生物技术方法获得的高遗传和植物检疫质量的种子。为此,根据体外繁殖技术建立的环境和个人无菌要求,需要对过程进行严格控制。然而,目前的质量控制体系存在着一组与它们之间互不相关的信息相关的限制和不足,这使得无法确定和快速确定生产损失的原因。此外,它没有与生产过程的操作规程相辅相成。通过设计和实施一系列质量控制系统和操作程序的改进,这个问题得到了解决。这些通过一组指标的结果得到验证:交付的产品达到100%的客户满意度,体外生产损失3.8%,体外建立存活率95%,培养基质量生产99.3%,体外植物在驯化过程中存活率93%,等等。所有这些都导致了生产计划的100%执行。
{"title":"Improvement of quality control system of the in vitro production of sugarcane","authors":"Miguel Suárez Castellá, C. Galian, J. Cabral, Rafael Gómez Kosky, Aydiloide Bernal Villegas, Irenaldo Delgado Mora, Dunia Nuñez Jaramillo, Midiala Bermúdez Calimano, Edel Toledo Rodríguez","doi":"10.36995/j.recyt.2022.37.007","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.007","url":null,"abstract":"The Sugarcane Biofactory at the Villa Clara Center Sugarcane Research Territorial Station plays a vital role in sugarcane production, since it provides seeds of high genetic and phytosanitary quality obtained by biotechnological methods. For this, strict control of the processes is required, derived from the requirements of environmental and personal asepsis established by in vitro propagation technology. However, the current quality control system presents a group of limitations and insufficiencies related to their information that were not related to each other, which makes it impossible to determine with certainty and speed the causes of production losses. Additionally, it is not complemented with operating procedures of the processes that are carried out in production. This problem was solved with the design and implementation of a group of improvements in the quality control system and operating procedures. These are validated by the results in a group of indicators: 100% customer satisfaction is achieved for the productions delivered, 3.8% lost in vitro production, 95% viable in vitro establishment, 99.3% of culture media produced with quality, 93% survival of in vitro plants during acclimatization, among others. All of this led to 100% compliance with the production plan.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73054286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sustainable management of construction waste in the Metropolitan Area of Misiones 米西奥内斯大都市区建筑垃圾的可持续管理
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.004
C. G. Sambiasi, A. E. Pascual Barrera, Ana María Sambiasi
The Metropolitan Area of Misiones does not have an adequate treatment of construction and demolition waste (CDW) by the municipalities that comprise it, so they do not reach the bases of sustainable development. The aim of the article was to present a model for the quantification of CDW, developing a case study corresponding to the foundations of 154 social housing units located in the reference area by applying the Weighted Transfer Method. The adoption of this method was based on using different construction cost bases and quantifying the CDW expected to be generated in the work, obtaining the information of each element, material of the specifications and the spreadsheet, and the project budget and then organizing it according to the codification of the European Waste List. Finally, the mathematical model generated from the Weighted Transfer Method was applied to convert the resources consumed into the volume of concrete, steel and soil waste generated during the foundation of 154 social housing units. It was concluded that the model fulfils the premises of the work and that its application will support decision making regarding CDW management.
米西奥内斯大都市区的市政当局没有对建筑和拆除废物(CDW)进行适当的处理,因此它们没有达到可持续发展的基础。本文的目的是提出一个量化CDW的模型,通过应用加权转移法对参考区域154个社会住房单元的基础进行案例研究。该方法的采用是基于使用不同的建设成本基础,量化工作中预计产生的CDW,获得每个元素的信息,规格材料和电子表格,以及项目预算,然后根据欧洲废物清单的编纂进行组织。最后,运用加权转移法生成的数学模型,将154套社会保障住房基础建设过程中消耗的资源转化为产生的混凝土、钢材和土壤废弃物体积。结果表明,该模型满足了本研究的前提条件,其应用将为CDW管理决策提供支持。
{"title":"Sustainable management of construction waste in the Metropolitan Area of Misiones","authors":"C. G. Sambiasi, A. E. Pascual Barrera, Ana María Sambiasi","doi":"10.36995/j.recyt.2022.37.004","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.004","url":null,"abstract":"The Metropolitan Area of Misiones does not have an adequate treatment of construction and demolition waste (CDW) by the municipalities that comprise it, so they do not reach the bases of sustainable development. The aim of the article was to present a model for the quantification of CDW, developing a case study corresponding to the foundations of 154 social housing units located in the reference area by applying the Weighted Transfer Method. The adoption of this method was based on using different construction cost bases and quantifying the CDW expected to be generated in the work, obtaining the information of each element, material of the specifications and the spreadsheet, and the project budget and then organizing it according to the codification of the European Waste List. Finally, the mathematical model generated from the Weighted Transfer Method was applied to convert the resources consumed into the volume of concrete, steel and soil waste generated during the foundation of 154 social housing units. It was concluded that the model fulfils the premises of the work and that its application will support decision making regarding CDW management.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83869092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frecuency of carbapenemase-producing enterobacteriaceae in anal swabs from an adult unit intensive care 产碳青霉烯酶肠杆菌科在成人重症监护单位肛门拭子中的频率
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.010
Augusto J. Vallejos, M. F. Tracogna, Mariana C. Carol Rey, Matías E. Bregant, M. Fernández, M. Cattana, María L Gariboglio Vázquez
The carbapenemase-producing enterobacteriaceae (CPE) are one of the main concerns of global health, mainly those that are encoded by plasmids. The aim was to describe the progress of colonization by CPE in anal swabs of patients of intensive care unit (ICU) and COVID-ICU in an adult hospital from Chaco province, Argentina. A descriptive retrospective study was carried out between 2021 January to August. 379 anal swabs were studied, in 26% (n=98) CPE were detected. K. pneumoniae was the more frequent isolate. In January, in COVID-ICU, 18% of anal swabs where positive, being all identified as KPC carbapenemase. In August, in COVID-ICU, the total of positive anal swab raised to 81% and all detected carbapenemase were MBL type. In ICU, the percentage of positive anal swabs increased from 14% in January to 49% in August, where both KPC and MBL carbapenemases were detected. Of The total of colonized patients, 15% developed CPE infection.Active surveillance and control measures are necessary to keep down the spread of CPE.
产生碳青霉烯酶的肠杆菌科(CPE)是全球健康的主要问题之一,主要是那些由质粒编码的肠杆菌。目的是描述CPE在阿根廷查科省一家成人医院重症监护病房(ICU)和COVID-ICU患者肛门拭子中的定植进展。描述性回顾性研究于2021年1月至8月进行,共收集肛拭子379份,检出CPE 26% (n=98)。肺炎克雷伯菌是最常见的分离菌。1月,在COVID-ICU, 18%的肛门拭子呈阳性,全部被确定为KPC碳青霉烯酶。8月,在COVID-ICU,肛门拭子阳性总数上升至81%,检测到的碳青霉烯酶均为MBL型。在ICU,肛门棉签阳性比例从1月的14%上升到8月的49%,同时检测到KPC和MBL碳青霉烯酶。在所有定植的患者中,15%发生CPE感染。必须采取积极的监测和控制措施,以遏制CPE的传播。
{"title":"Frecuency of carbapenemase-producing enterobacteriaceae in anal swabs from an adult unit intensive care","authors":"Augusto J. Vallejos, M. F. Tracogna, Mariana C. Carol Rey, Matías E. Bregant, M. Fernández, M. Cattana, María L Gariboglio Vázquez","doi":"10.36995/j.recyt.2022.37.010","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.010","url":null,"abstract":"The carbapenemase-producing enterobacteriaceae (CPE) are one of the main concerns of global health, mainly those that are encoded by plasmids. The aim was to describe the progress of colonization by CPE in anal swabs of patients of intensive care unit (ICU) and COVID-ICU in an adult hospital from Chaco province, Argentina. A descriptive retrospective study was carried out between 2021 January to August. 379 anal swabs were studied, in 26% (n=98) CPE were detected. K. pneumoniae was the more frequent isolate. In January, in COVID-ICU, 18% of anal swabs where positive, being all identified as KPC carbapenemase. In August, in COVID-ICU, the total of positive anal swab raised to 81% and all detected carbapenemase were MBL type. In ICU, the percentage of positive anal swabs increased from 14% in January to 49% in August, where both KPC and MBL carbapenemases were detected. Of The total of colonized patients, 15% developed CPE infection.\u0000Active surveillance and control measures are necessary to keep down the spread of CPE.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81567261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simulation of the ethylene oxide production process in ChemCAD® simulator 在ChemCAD®模拟器中模拟环氧乙烷生产过程
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.002
Amaury Pérez Sánchez, José G. Baltá García, Jesús R. Montalván Viart, Elizabeth Ranero González, E. J. Pérez Sánchez
Ethylene oxide is an important industrial chemical compound used as an intermediate in the production of glycols and other plastics. In the present work, the process of ethylene oxide (EO) production from the catalytic oxidation of ethylene was simulated using the ChemCAD® simulator. Heat curves were obtained for each of the shell and tube heat exchangers used, while the flow rate and composition of the most important streams involved in the production process were determined. A sensitivity study was also carried out to establish the influence of a decrease in the feed temperature of the wash water to the absorbers on the amount of EO to be obtained in the distillation column. 22,163.5 kg/h of EO is obtained from the top of the distillation column with a purity of 98.29 %. The wash water should be fed to the absorbers at a temperature of 5 ºC to maximise the amount of EO to be obtained in the distillation column.
环氧乙烷是一种重要的工业化合物,用作生产乙二醇和其他塑料的中间体。在本工作中,使用ChemCAD®模拟器模拟了乙烯催化氧化生产环氧乙烷(EO)的过程。得到了所使用的每个管壳式换热器的热曲线,同时确定了生产过程中最重要流的流量和组成。还进行了灵敏度研究,以确定洗涤水进料温度的降低对精馏塔中获得的EO量的影响。精馏塔塔顶所得EO为22163.5 kg/h,纯度为98.29%。洗涤水应在5℃的温度下注入吸收器,以最大限度地提高精馏塔中获得的EO量。
{"title":"Simulation of the ethylene oxide production process in ChemCAD® simulator","authors":"Amaury Pérez Sánchez, José G. Baltá García, Jesús R. Montalván Viart, Elizabeth Ranero González, E. J. Pérez Sánchez","doi":"10.36995/j.recyt.2022.37.002","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.002","url":null,"abstract":"Ethylene oxide is an important industrial chemical compound used as an intermediate in the production of glycols and other plastics. In the present work, the process of ethylene oxide (EO) production from the catalytic oxidation of ethylene was simulated using the ChemCAD® simulator. Heat curves were obtained for each of the shell and tube heat exchangers used, while the flow rate and composition of the most important streams involved in the production process were determined. A sensitivity study was also carried out to establish the influence of a decrease in the feed temperature of the wash water to the absorbers on the amount of EO to be obtained in the distillation column. 22,163.5 kg/h of EO is obtained from the top of the distillation column with a purity of 98.29 %. The wash water should be fed to the absorbers at a temperature of 5 ºC to maximise the amount of EO to be obtained in the distillation column.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77978979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Genetic and epi-genetic alterations of the PTEN gene: key in the relationship between type 2 diabetes and cancer PTEN基因的遗传和表观遗传改变:2型糖尿病和癌症关系的关键
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.009
Alan Rolando Ayala Schimpf, María Mercedes Formichela, M. B. Mascheroni, Donovan Rivero, Marcela Luján Chamorro, Valeria Portillo, P. Zapata, C. Ferri
Cancer pathogenesis has been associated with genetic and epigenetic alterations that may lead to the inactivation or decrease of tumor-suppressor genes, such as the PTEN gene. In particular, alterations in the PI3K/PTEN signaling pathways are related to abnormalities associated with diabetes, metabolic syndrome, obesity and cardiovascular diseases. The aim of the study was to evaluate whether the expression levels of the PTEN gene, the 32-bp deletion in the PTEN gene, and the methylation in the PTEN promoter are associated with Type 2 Diabetes Mellitus(T2DM) and cancer development. Peripheral blood samples were obtained from a total of 70 patients of both sexes: 40 patients with T2DM and 30 patients with T2DM and cancer(T2DM+C). In this a novel report that assesses the upregulation of PTEN in T2DM, we observed that PTEN expression is higher in T2DM patients than in healthy individuals and markedly lower in T2DM patients with cancer than in T2DM patients without cancer. Hypermethylation of the PTEN promoter is more frequent in T2DM patients with cancer. Genetic and epigenetic alterations of the PTEN gene may be a key in the relationship between T2DM and cancer. PTEN expression may serve as a potential candidate biomarker for cancer development in T2DM patients.
癌症的发病机制与可能导致肿瘤抑制基因(如PTEN基因)失活或减少的遗传和表观遗传改变有关。特别是,PI3K/PTEN信号通路的改变与糖尿病、代谢综合征、肥胖和心血管疾病相关的异常有关。该研究的目的是评估PTEN基因的表达水平、PTEN基因32bp缺失和PTEN启动子甲基化是否与2型糖尿病(T2DM)和癌症发展相关。共采集了70例男女患者的外周血样本:40例T2DM患者和30例T2DM合并癌症(T2DM+C)患者。在这篇评估PTEN在T2DM中上调的新报告中,我们观察到PTEN在T2DM患者中的表达高于健康个体,而在T2DM合并癌症患者中的表达明显低于未患癌症的T2DM患者。PTEN启动子的高甲基化在T2DM合并癌症患者中更为常见。PTEN基因的遗传和表观遗传改变可能是T2DM和癌症之间关系的关键。PTEN表达可能作为T2DM患者癌症发展的潜在候选生物标志物。
{"title":"Genetic and epi-genetic alterations of the PTEN gene: key in the relationship between type 2 diabetes and cancer","authors":"Alan Rolando Ayala Schimpf, María Mercedes Formichela, M. B. Mascheroni, Donovan Rivero, Marcela Luján Chamorro, Valeria Portillo, P. Zapata, C. Ferri","doi":"10.36995/j.recyt.2022.37.009","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.009","url":null,"abstract":"Cancer pathogenesis has been associated with genetic and epigenetic alterations that may lead to the inactivation or decrease of tumor-suppressor genes, such as the PTEN gene. In particular, alterations in the PI3K/PTEN signaling pathways are related to abnormalities associated with diabetes, metabolic syndrome, obesity and cardiovascular diseases. The aim of the study was to evaluate whether the expression levels of the PTEN gene, the 32-bp deletion in the PTEN gene, and the methylation in the PTEN promoter are associated with Type 2 Diabetes Mellitus(T2DM) and cancer development. Peripheral blood samples were obtained from a total of 70 patients of both sexes: 40 patients with T2DM and 30 patients with T2DM and cancer(T2DM+C). In this a novel report that assesses the upregulation of PTEN in T2DM, we observed that PTEN expression is higher in T2DM patients than in healthy individuals and markedly lower in T2DM patients with cancer than in T2DM patients without cancer. Hypermethylation of the PTEN promoter is more frequent in T2DM patients with cancer. Genetic and epigenetic alterations of the PTEN gene may be a key in the relationship between T2DM and cancer. PTEN expression may serve as a potential candidate biomarker for cancer development in T2DM patients.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79513166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of clay ceramic microstructure with the glass waste incorporation 掺加玻璃废料的粘土陶瓷微观结构分析
Pub Date : 2022-05-10 DOI: 10.36995/j.recyt.2022.37.003
Alexandre Zaccaron, Ra Frizzo, E. Zanoni, L. Nieves, Fábio Rosso, V. Nandi, O. Montedo, A. Bernardin
The study examined the microstructure of ceramics with the addition of glass waste at different temperatures ranging from 800 to 1000 °C. Samples were molded by piston without vacuum, with the incorporation of 20% (weight) of glass bottles, with coarse particles, for a better identification. The raw materials were analyzed chemically and mineralogically by XRF and XRD. The microstructural characterization was carried out by scanning electron microscopy, SEM and optical microscopy, in order to analyze the behavior of grain boundary and the interaction between the materials. The results showed that there is compatibility between the materials, where the increase in temperature causes a greater interaction, but when this temperature exceeds 900 ° C, pores appear in the glass, a phenomenon known as overfiring.
在800 ~ 1000℃的不同温度下,研究了添加玻璃废料后陶瓷的微观结构。样品采用活塞无真空成型,加入20%(重量)的玻璃瓶,颗粒较粗,便于鉴别。采用XRF和XRD对原料进行了化学和矿物学分析。采用扫描电子显微镜、扫描电子显微镜和光学显微镜对材料进行了微观组织表征,分析了材料的晶界行为和材料间的相互作用。结果表明,材料之间存在相容性,温度升高会导致更大的相互作用,但当温度超过900℃时,玻璃中出现孔隙,这种现象称为过烧。
{"title":"Analysis of clay ceramic microstructure with the glass waste incorporation","authors":"Alexandre Zaccaron, Ra Frizzo, E. Zanoni, L. Nieves, Fábio Rosso, V. Nandi, O. Montedo, A. Bernardin","doi":"10.36995/j.recyt.2022.37.003","DOIUrl":"https://doi.org/10.36995/j.recyt.2022.37.003","url":null,"abstract":"The study examined the microstructure of ceramics with the addition of glass waste at different temperatures ranging from 800 to 1000 °C. Samples were molded by piston without vacuum, with the incorporation of 20% (weight) of glass bottles, with coarse particles, for a better identification. The raw materials were analyzed chemically and mineralogically by XRF and XRD. The microstructural characterization was carried out by scanning electron microscopy, SEM and optical microscopy, in order to analyze the behavior of grain boundary and the interaction between the materials. The results showed that there is compatibility between the materials, where the increase in temperature causes a greater interaction, but when this temperature exceeds 900 ° C, pores appear in the glass, a phenomenon known as overfiring.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86484255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Racionalidad del agricultor de berenjena (Solanum melongena L.) desde el punto de vista de los costos de producción en la Región Caribe de Colombia 哥伦比亚加勒比地区茄子(Solanum melongena L.)农民从生产成本角度的合理性
Pub Date : 2022-01-02 DOI: 10.18779/cyt.v15i1.536
Antonio María Martínez Reina
Dentro de las hortalizas que se cultivan en la Región Caribe, en especial en el Valle del Sinú y la Región de Sabanas, Colombia, la berenjena ha alcanzado altos niveles de adaptación y posee gran aceptación en la dieta de los habitantes. No obstante, son escasos los estudios sobre la eficiencia económica del sistema de producción. Este trabajo tuvo como objetivo determinar la eficiencia técnica del cultivo mediane un análisis del costo de producción en los tres elementos básicos que lo componen como son: la mano de obra, los insumos y los servicios. Con datos obtenidos de una encuesta aplicada a 62 agricultores seleccionados por el método de muestreo simple, la información se analizó a través de estadísticas descriptivas, análisis de correlación y la formulación de un modelo econométrico tipo Cobb Douglas que plantea una relación funcional entre las cantidades de producto y los factores que intervienen en la producción. Los resultados muestran que un aumento del uso de los insumos causa el mayor incremento en el costo total, por su parte la mano de obra lo son en menor proporción y por ultimo los servicios son los que menos inciden en el aumento de los costos. Se concluye que hay ineficiencia en el uso de los factores de producción del 52% como resultado de la diferencia entre los costos reales y los costos potenciales, es decir que por más que el productor trata de usar bien los recursos incurre en cotos adicionales del orden de $ 2.123.283 COP por hectárea.
在加勒比地区种植的蔬菜中,特别是在sinu山谷和哥伦比亚的Sabanas地区,茄子已经达到了高度的适应水平,在居民的饮食中有很大的接受度。然而,关于生产系统的经济效率的研究很少。本研究的目的是确定中位数作物的技术效率,并分析构成中位数作物的三个基本要素的生产成本:劳动力、投入和服务。调查与数据应用到62的农民经过简单的抽样方法,信息通过描述性统计分析、相关分析和制定计量模型类型科布·道格拉斯所构成的函数关系产品数量和参与生产因素。本研究的目的是分析在墨西哥,投入使用的增加导致总成本的增加,而劳动力的增加只占总成本的一小部分,最后,服务对成本增加的影响较小。由此断定有低效使用生产要素52%由于成本和费用的潜在差异,也就是说比尝试使用好的制作人美元的额外资源应负有cotos秩序2123283持久性有机污染物每公顷。
{"title":"Racionalidad del agricultor de berenjena (Solanum melongena L.) desde el punto de vista de los costos de producción en la Región Caribe de Colombia","authors":"Antonio María Martínez Reina","doi":"10.18779/cyt.v15i1.536","DOIUrl":"https://doi.org/10.18779/cyt.v15i1.536","url":null,"abstract":"Dentro de las hortalizas que se cultivan en la Región Caribe, en especial en el Valle del Sinú y la Región de Sabanas, Colombia, la berenjena ha alcanzado altos niveles de adaptación y posee gran aceptación en la dieta de los habitantes. No obstante, son escasos los estudios sobre la eficiencia económica del sistema de producción. Este trabajo tuvo como objetivo determinar la eficiencia técnica del cultivo mediane un análisis del costo de producción en los tres elementos básicos que lo componen como son: la mano de obra, los insumos y los servicios. Con datos obtenidos de una encuesta aplicada a 62 agricultores seleccionados por el método de muestreo simple, la información se analizó a través de estadísticas descriptivas, análisis de correlación y la formulación de un modelo econométrico tipo Cobb Douglas que plantea una relación funcional entre las cantidades de producto y los factores que intervienen en la producción. Los resultados muestran que un aumento del uso de los insumos causa el mayor incremento en el costo total, por su parte la mano de obra lo son en menor proporción y por ultimo los servicios son los que menos inciden en el aumento de los costos. Se concluye que hay ineficiencia en el uso de los factores de producción del 52% como resultado de la diferencia entre los costos reales y los costos potenciales, es decir que por más que el productor trata de usar bien los recursos incurre en cotos adicionales del orden de $ 2.123.283 COP por hectárea.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90251611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Situación actual, problemas fitosanitarios y alternativas de manejo de la teca en Ecuador 厄瓜多尔柚木的现状、植物检疫问题和管理方案
Pub Date : 2021-12-31 DOI: 10.18779/cyt.v14i2.499
Edwin José Borja Borja, Miguel Guara Requena, Danilo Isaac Vera Coello
Tectona grandis L.f. (teca) es un recurso forestal con gran demanda internacional, que en Ecuador representa un importante ingreso que genera anualmente un aproximado de 37 millones de dólares. Sin embargo, en los últimos años se ha visto amenazado por un problema fitosanitario denominado “muerte regresiva”. Con el objeto de determinar el perfil de los productores de teca y la incidencia de la enfermedad, se levantó información mediante una encuesta semiestructurada en 77 plantaciones, considerando los criterios de género, grupo étnico, rango de edad, nivel de educación, provincia y número de hectáreas. De entre los resultados obtenidos, resaltar que la edad de los entrevistados varía entre los 18 y 96 años, donde el 86.15% corresponde al género masculino y el 13.85% al femenino. El 75.33% son de etnia mestiza, el 10.39% montuvio y el 3.9% de otras etnias. La propiedad reside en los hombres en un 75.32%, en las mujeres en un 11.69%, y en la empresa privada o instituciones en un 12.99%. El 61.05% de los productores indicaron tener el problema fitosanitario, pero tras la evaluación del estado de las plantaciones se constató que la enfermedad se presentó en el 92.21%, por tanto, un 31.16% de los productores desconocen de la enfermedad, que varía entre el 0 y el 49% de incidencia entre las provincias ecuatorianas. Dado que este problema fitosanitario está en la mayoría de las plantaciones se recomienda manejos culturales para reducir su dispersión.
柚木是一种国际需求巨大的森林资源,在厄瓜多尔代表着重要的收入,每年产生约3700万美元。然而,近年来,它受到一种被称为“退化死亡”的植物检疫问题的威胁。为了确定柚木生产者的情况和疾病的发病率,考虑到性别、民族、年龄、教育水平、省份和公顷数的标准,对77个种植园进行了半结构化调查,收集了信息。在获得的结果中,值得注意的是,受访者的年龄在18至96岁之间,其中86.15%为男性,13.85%为女性。= =地理= =根据美国人口普查局的数据,该县的总面积为,其中土地和(1.0%)水。75.32%的财产属于男性,11.69%属于女性,12.99%属于私营企业或机构。生产国61.05%表示有麻烦的植物,但种植园的状况进行评估后发现疾病出现在92.21%,因此一个31.16%生产国并不了解,这一疾病发病率的0至49%的厄瓜多尔各省之间。由于这种植物检疫问题存在于大多数种植园,建议采用栽培管理方法来减少其扩散。
{"title":"Situación actual, problemas fitosanitarios y alternativas de manejo de la teca en Ecuador","authors":"Edwin José Borja Borja, Miguel Guara Requena, Danilo Isaac Vera Coello","doi":"10.18779/cyt.v14i2.499","DOIUrl":"https://doi.org/10.18779/cyt.v14i2.499","url":null,"abstract":"Tectona grandis L.f. (teca) es un recurso forestal con gran demanda internacional, que en Ecuador representa un importante ingreso que genera anualmente un aproximado de 37 millones de dólares. Sin embargo, en los últimos años se ha visto amenazado por un problema fitosanitario denominado “muerte regresiva”. Con el objeto de determinar el perfil de los productores de teca y la incidencia de la enfermedad, se levantó información mediante una encuesta semiestructurada en 77 plantaciones, considerando los criterios de género, grupo étnico, rango de edad, nivel de educación, provincia y número de hectáreas. De entre los resultados obtenidos, resaltar que la edad de los entrevistados varía entre los 18 y 96 años, donde el 86.15% corresponde al género masculino y el 13.85% al femenino. El 75.33% son de etnia mestiza, el 10.39% montuvio y el 3.9% de otras etnias. La propiedad reside en los hombres en un 75.32%, en las mujeres en un 11.69%, y en la empresa privada o instituciones en un 12.99%. El 61.05% de los productores indicaron tener el problema fitosanitario, pero tras la evaluación del estado de las plantaciones se constató que la enfermedad se presentó en el 92.21%, por tanto, un 31.16% de los productores desconocen de la enfermedad, que varía entre el 0 y el 49% de incidencia entre las provincias ecuatorianas. Dado que este problema fitosanitario está en la mayoría de las plantaciones se recomienda manejos culturales para reducir su dispersión.","PeriodicalId":21243,"journal":{"name":"Revista de Ciencia y Tecnología","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89268435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Revista de Ciencia y Tecnología
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1